Background: The primary goal of hand hygiene is to reduce infectious disease rates. We examined if a nursing home’s participation in a hand hygiene intervention resulted in residents having fewer healthcare associated infections (HAIs) when compared to nursing homes without the hand hygiene intervention. Methods: This study is a part of a cluster randomized controlled trial (RCT) in 33 nursing homes to improve hand hygiene (HANDSOME). The incidence of five illnesses was followed over 13 months: gastroenteritis, influenza-like illness, pneumonia, urinary tract infections and infections from methicillin-resistant Staphylococcus aureus (MRSA). Incidence rates per study arm were reported for baseline (October–December 2016) and two follow-up periods (January–April 2017, May–October 2017). HAI rates were compared in a Poisson multilevel analysis, correcting for baseline differences (the baseline infection incidence and the size of the nursing home), clustering of observations within nursing homes, and period in the study. Results: There was statistically significantly more gastroenteritis (p < 0.001) and statistically significantly less influenza-like illness (p < 0.01) in the intervention arm when compared to the control arm. There were no statistically significant differences or pneumonia, urinary tract infections, and MRSA infections in the intervention arm when compared to the control arm. In a sensitivity analysis, gastroenteritis was no longer statistically significantly higher in the intervention arm (p = 0.92). Conclusions: As in comparable studies, we could not conclusively demonstrate the effectiveness of an HH intervention in reducing HAIs among residents of nursing homes, despite the use of clearly defined outcome measures, a standardized reporting instrument, and directly observed HH in a multicenter cluster RCT. Trial registration Netherlands Trial Register, trial NL6049 (NTR6188). Registered October 25, 2016, https://www.trialregister.nl/trial/6049.
\nAdditional Metadata doi.org/10.1186/s13756-021-00946-3, hdl.handle.net/1765/135845 Antimicrobial Resistance and Infection Control Organisation Erasmus MC: University Medical Center Rotterdam\nGR (Gwen) Teesing, J.H. (Jan hendrik) Richardus, D. (Daan) Nieboer, MWF Petrignani, V. (Vicki) Erasmus, A Verduijn-Leenman, … H.A.C.M. (Hélène) Voeten. (2021). The effect of a hand hygiene intervention on infections in residents of nursing homes.\nAntimicrobial Resistance and Infection Control, 10(1). doi:10.1186/s13756-021-00946-3", "pred_label": "__label__POS", "pred_score_pos": 0.5132530927658081} +{"content": "A well-adjusted amplifier gain eliminates sound clipping and other poor sound outputs. But adjusting a car amplifier gain has not been the easiest task for car owners. When adjusted to the right frequency, your gain matches your amp input level with your stereo output levels, thereby producing just the right sound for your car. How to adjust car amplifier gain for the best performance?\nAdjusting a car amplifier gain has a simple option and a complex option, which requires a bit of calculation. Nonetheless, you can adjust your car amplifier gain by simply adjusting the stereo volume to reach 70% capacity and the gain volume to a preferred high level, and then readjust the volume button to suit your preference and the current music. This method of gain adjustment can be done without sound tools.\nWhile our ears are great for detecting and adjusting sound, most car owners rely on tools to help them adjust their amp gain.\nOthers Ways Of Adjusting Your Car Amp Gain\nThe only guaranteed means of enjoying quality sound from your stereo system is adjusting it with a tool or music. A well-adjusted amplifier gain means enjoying the full range of any music playing in your car. It also means enjoying the notes, thereby assuring the best music experience in your car.\n● Adjust Gain With Music\nThe easiest way to adjust your amplifier gain is by listening to music in your car.\nPlay a familiar song and find distortions while you adjust the volume and gain buttons. Start by turning both the volume and gain button down. Once you’re sure that your volume and gain buttons are down, turn on your stereo and play your favorite song.\nYou should play a song you’re familiar with as it helps you judge the quality of the sound and aids the discovery of sound distortions. Next, you’ll need to turn the volume button back up, but not to full capacity as it could cause distortions from your amp.\nRather, leave it at 70% while slowly turning up your gain volume to a preferred high volume. Find distortions as you tweak the gain button and then leave the gain control below that level.\nWithout the distortions from the gain, you can simply use your volume button to adjust the music to a preferred level. Note: your gain button is not a volume button. While it might be tempting to tweak your gain button for maximum sound, avoiding it will help prevent distortions in your music.\n● Adjust Gain With Test Tone\nWhile adjusting your amp gain with your favorite song and your ear might yield good results, adjusting with test tone has been known to yield more satisfactory results. A more cumbersome option but one that guarantees amazing sound output.\nA test tone indicates a single note being played at a particular frequency and can be downloaded from trusted websites to test your amp gain. The test results can be derived in two ways, either through a Speaker or an Oscillator.\nA test tone with a speaker is a cheaper and more realistic way to adjust amplifier gain. But first, you should level your amp’s bass boost and EQ receiver volume. Play the test tone and adjust the gain button until there is a buzzing sound. Slightly return the volume and wait for the humming sound a test tone produces.\nThe second option, test tone with an Oscilloscope screen, is considered the best option as it provides the user with a clear image of the sound wavelength, thereby showing the clear points and distorted points. This provides you with accurate data for adjusting your amplifier gain.\n● Adjust Gain With Digital MultiMeter\nA digital multimeter helps to adjust amp gain by accurately matching your amps input level with your stereo’s output level. This method of adjusting amp gain is more accurate but requires a bit of maths to test the output of your amplifier’s AC voltage.\nHere are the steps to follow: 1. Disconnect all accessories\nDisconnect your subwoofers and speakers from your car amplifier, while leaving it plugged in. It is recommended to remove only the positive terminals of your accessories.\n2. Equalizer and Gain setting to zero\nThe next step is to completely turn off your equalizer or turn the settings such as Loudness, Bass Boost, equalizer functions, and Treble.\n3. Measure Speaker Resistance\nNext, test the resistance of your speakers by connecting to your amp using a multimeter. But first, determine the positive and negative terminals of your amp before connecting the black probe to the negative and the red to the positive. Settle for any ohm resistance between 2, 4, 8, or 16 ohms.\n4. Check for the speaker’s recommended wattage\nAfter measuring your speaker’s resistance, the next step is to check for your speaker’s recommended wattage to make sure it is balanced with your ohm resistance for optimal tests results.\n5. Calculate the Required A.C Voltage\nNext, we do the maths. Calculate the target voltage of your amp by using a variation of Ohm’s law where V = √(P.R) and V is the target voltage and P, the wattage with R being the resistance. To derive a conclusion, multiply your Watts with the Ohm, and find the square too of your answer.\n6. Set Volume to ⅔\nNext, set the volume at ⅔ of its full capacity. Most authorities recommend that you set your stereo volume to 70 or 75% to prevent hearing distorted sounds.\n7. Insert Multimedia Probe\nInsert the negative probe and positive probes into the corresponding terminals of your car amplifier.\n8. Play Tone\nAs a last and conclusive step, play a 6p Hz test tone on your stereo. You can buy a CD or download a tone online. Adjust the gain button until the multimedia reads the desired Ac Output voltage. Enjoy music on your Stereo like never before.\nTips for Adjusting Amplifier Gain\nYou should follow the steps as it is for the best results. However, below are some additional tips to help you adjust your amplifier gain correctly.\n1. Don’t Maximize Stereo Volume\nAs mentioned earlier, keep your stereo volume at ⅔ of its full capacity. For example, if your maximum volume is 100, then it should be 70% to avoid sound distortion while testing your amplifier gain.\n2. Set Your Separate Amplifier Gain Individually\nIf you own more than 1 amplifier in your car, setting them individually helps to get the best results. By so doing, you easily identify the amplifier causing the distortion and adjust it accordingly. Adjusting all the gains on all your amplifiers at the same time will only increase your workload and reduce the efficiency of the test.\nHow to tune For Bass Sound?\nMore car owners are constantly looking for new ways of amping up their bass car stereo as it provides them the best in-car listening experience. But how do you tune for bass sound?\nThe first step to tuning for bass sound in your car stereo is eliminating the distortion. Adjust the stereo volume until you notice a distorted sound. Then slightly tune it down until you no longer hear the distortion. Next, turn off the bass boost and low pass filter.\nPlay your music at ¼ and slowly turn up your subwoofers until you hear the distortion, and tune it back down until you can only hear the clear sound of the bass in your music.\nAdjusting your amplifier gain helps you enjoy clear sound. The best methods to adjust your gain includes music (listening), test tone, and a multimeter. However, for the best results, we recommend an oscilloscope to test tone or multimedia, which involves a bit of calculation.\nPay attention to the warnings and use these methods by the stayed precautions by your car manufacturer. Be quick to visit a professional in the case of a malfunction to avoid any further damage to your amplifier.", "pred_label": "__label__POS", "pred_score_pos": 0.571968674659729} +{"content": "In this review, Richard Johnson et al. argue fructose—which makes up half of table sugar and high-fructose corn syrup—has a unique metabolic impact that might directly lead to diabetes, particularly when consumed in excess of 50 grams per day.\nFructose, unlike other sugars, is directly metabolized in the liver, where it increases liver fat, raises triglyceride levels and increases uric acid when consumed chronically. Over time, this can lead to insulin resistance; hypertension; damage to the liver, kidneys and blood vessels; metabolic syndrome; and diabetes. Human, animal and epidemiological studies are reviewed supporting both the correlation between increased sugar intake and metabolic disease on a population level and the various mechanisms by which fructose can lead to metabolic damage.\nThey conclude that the current evidence suggests sugar is detrimental in more ways than merely being “empty calories,” and that if additional research supports the hypothesis that fructose (and so sugars) promotes metabolic disease, it would suggest removing fructose from the diet can prevent obesity and metabolic syndrome, as well as the conditions that follow from them.", "pred_label": "__label__POS", "pred_score_pos": 0.9710870385169983} +{"content": "While it often seems as if IRS rules and regulations are black and white, leaving little room for interpretation, that's not the case. Whenever Congress passes new legislation, much is often left open to interpretation, particularly if the IRS doesn't have time to develop revenue procedures quickly. Rather than simply hope that we're doing it right and cross our fingers, we can develop tax positions with little guidance and still protect ourselves from liability if we explain the position to the IRS and have a “reasonable basis” for the tax position. We use Disclosure Statement, Form 8275, a nifty IRS penalty defense weapon, to explain these positions. With the wide range of changes to the tax code due to COVID-19 pandemic legislation, many of which have no authoritative tax guidance, it's time to take a look at how to protect yourself from accuracy-related tax penalties.\nDisclosure Statement, Form 8275\nTaxpayers and tax preparers use Disclosure Statement, Form 8275, to keep themselves out of trouble. We use this form to disclose tax positions that the tax return doesn't adequately reveal or explain to avoid penalties. If the Disclosure Statement reveals a reasonable basis for a tax reporting position, it can:\nProtect a taxpayer from an accuracy-related penalty that's the result of substantially understating income tax for non-tax shelter items, Remove exposure to a 40% penalty for transactions “lacking in economic substance” and Protect a tax preparer from penalties for tax understatements resulting from unreasonable positions or disregarding the rules.\nWith new COVID-19 tax legislation, we have a breadth of new, hazy tax provisions that aren't clear. In many cases, if we are uncertain about tax treatment for a new provision, the IRS will consider it disclosed if it's properly entered on a return. But if the IRS's revenue procedures don't clear up the uncertainty, it seems safest to use a disclosure statement on Form 8275 to avoid a dispute with the IRS down the line.\nIf you're facing tax preparation uncertainty in the wake of tax regulations stemming from the new Coronavirus tax relief bills, it's time to discuss the matter with an experienced tax professional. You don't have to unravel new IRS regulations, disclosure statements, and revenue procedures on your own. If you need help, call Senior Partner, Tax Controversy Attorney, and former IRS attorney Brandon A. Keim at (602) 200-7399 or contact him online to discuss your options.", "pred_label": "__label__POS", "pred_score_pos": 0.7137725353240967} +{"content": "Assisting to deliver better and more visible content\nPublishers are navigating through a turbulent phase in the market right now. Digital transformation has brought about new players, diverse content formats, new-age users, and emerging business models. The new dynamics in the market present both challenges and opportunities.\nStraive works with publishers across different industry segments, including academic & professional, school, higher education, and trade. Additionally, we support a wide range of products, including journals, books, MRWs, conference proceedings, course material, magazines, and databases.\nWe offer end-to-end management of the content lifecycle from manuscript development to publishing. Our full-service offering includes author management, schedule management, rights management, design services, and print/digital deliverables.\nStraive offers a full suite of technology and digital content services, enabling the digital enrichment of existing products and creating “born-digital” products.\nWe unlock business value from unstructured data for insights, thus enabling better business decisions.\nOur intelligent platforms and the work that we do in our Innovation Labs help in the efficient production of content, digital, and data products.\nWe offer multi-channel, 24x7 support managing fulfillment, helpdesk, technical support, sales & marketing, and community management.\nOur solutioning team is eager to know about your challenge and how we can help.", "pred_label": "__label__POS", "pred_score_pos": 0.9883447289466858} +{"content": "The hardest is foods I am not familiar with. Gyros, I lost that one; I don't like tzatziki sauce very much. I did kimchi in Korea, which was rough: fermented cabbage and spicy.\nI love king crab a lot. I love good Mexican food, good tacos, and chile rellenos.\nI know I hold the contest record for downing the most hot dogs, and the record for most Nathan's Famous Hot Dog Contest championships, but it was really cool to be a part of a Guinness World Records official attempt.\nI know that when I'm fitter, I breathe better. If I breathe better, I can eat more.\nMy weight does fluctuate, and there are extreme highs and lows in my blood sugar, so there is some worry about diabetes.\nThere have always been a lot of critics of competitive eating. You can be a critic of anything. It's easy to be a critic. You can say negative things about golf, the amount of water wasted on golf courses. Or NASCAR. There are wastes in everything.\nThere are times when I'm not eating buns if I'm on a low carb diet. I'll have hot dogs and romaine lettuce, but if I'm at a baseball game, I'm always eating a hot dog.\nSo now I'm 'the hot dog guy,' which isn't bad. I take it in stride. It's not like it was my goal in life. I'm having fun with it.\nThey don't sell the Nathan's hot dogs hardly anywhere in the West Coast. So I have to special order them, and I just end up getting Nathan's to ship them to me.\nI think my body was built to eat 68 hot dogs. It's natural.\nHonoring our nation's heroes and their caregivers is a cause very important to me - especially on Independence Day.\nI've strained some muscles here and there, in my throat, even my jaw. Nothing that doesn't heal quickly.\nThere's nothing pretty about competitive eating. It might be uncouth, but it is fun, and it is lighthearted.\nIt's addicting, beating the heck out of people and eating hot dogs and making people smile. I do feel like garbage afterwards, but so what? Most people feel like garbage after a long day of work.\nI think Peter King... he's kind of narrow-minded.\nI love food, and not surprisingly, I often suffer from stomach upsets when I overeat in general, let alone when I'm competing.\nI have the craziest dreams when I'm digesting a massive amount. It feels so real, it's psychedelic.\nYou need to stay calm the day of the contest. Not let the weather bother me and just relax.\nWhen I'm eating I try to make sure I can breathe through my nose the entire time. If I have to breathe through my mouth, there's no way I'm eating or swallowing.\nMake sure I'm chewing, swallowing, and breathing, my whole body is working together. I can just find a rhythm and keep going and going and going. It's my love of food.", "pred_label": "__label__POS", "pred_score_pos": 0.5166491866111755} +{"content": "To ask the Chancellor of the Exchequer, whether the impact assessments produced by banks when announcing a bank branch closure include an assessment of privacy provision at local post offices for confidentiality purposes.\nAnswered on\n6 September 2021\nThe major high street banks have been signed up to the Access to Banking Standard since May 2017, which commits them to ensure customers are well informed about branch closures, the bank’s reasons for closure and options for continued access to banking services.\nUnder the Access to Banking Standard, banks are expected to publish an Impact Assessment which ensures impacted customers understand what the alternatives are when a branch is closing, how they can be accessed, and what the bank will do to help or assist with all or each of those.\nThe Financial Conduct Authority (FCA) has also published guidance setting out its expectation of firms when they are deciding to reduce the number of their physical branches. The FCA expects firms to carefully consider the impact of a closure on a consumer’s needs and consider possible alternative access arrangements. Consumer needs could comprise physical access requirements, the need for privacy, or security for making transactions. This is particularly important for vulnerable customers, so they are not excluded from using everyday banking services.", "pred_label": "__label__POS", "pred_score_pos": 0.6435084342956543} +{"content": "[A case of necrotizing colitis presenting with hepatic portal venous gas and pneumatosis intestinalis].Song Jong Gyu,Koo Ja Seol,Kang Hyo Sung,Park Jin Yong,Kim Seoung Young,Hyun Jong Jin,Jung Sung Woo,Lee Sang WooThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chiHepatic portal venous gas is a very rare radiologic sign which is characterized by gas accumulation in the portal venous circulation. Pneumatosis intestinalis is also very rare and is characterized by multiple air cysts in the serosal or submucosal layers of the gastrointestinal tract walls. These two findings are caused by various pathological conditions and can develop individually or simultaneously. The latter is clinically more significant because it is frequently related to bowel ischemia or necrosis, and represents a poor prognosis. However, prognosis is more influenced by the severity of underlying disease rather than hepatic portal venous gas or pneumatosis intestinalis itself. If bowel ischemia or necrosis is the primary cause, emergency operation is very important to improve patient's prognosis. Herein, we report a case of necrotizing colitis presenting as hepatic portal venous gas and pneumatosis intestinalis which was successfully managed by early surgery.10.4166/kjg.2015.65.3.177", "pred_label": "__label__POS", "pred_score_pos": 0.9854133725166321} +{"content": "Trouble Eating Difficulty Chewing\nPain or difficulty when eating and chewing can be due to several causes. The trouble could stem from an issue with the teeth, the jaw, facial muscles, or tongue. This article will discuss two of the more common reasons for chewing difficulty along with ways to manage the issue.\nJaw Issue\nThe temporomandibular joint (TMJ) consists of two pairs of joints that connect the skull to lower jaw. The joint allows the jawbone to slide and rotate and can be found in front of the ears on both sides of the head. The joints facilitate talking and chewing and when one or both becomes painful or inflamed, the conditions is known as temporomandibular joint disorder (TMJD).\nThere are numerous causes of TMJD including:\nWear and tear Damage to the teeth surfaces Loose or missing teeth that have caused jawbone damage or misalignment of the lower and upper jaws Misaligned teeth or jaw Overuse of chewing muscles Damage or trauma Arthritis Tumors Infections in the jaw\nTMJD symptoms include:\nPain or tenderness in the jaw; may be present regardless of if TMJ is moving or not Trouble fully opening the mouth Difficulty or pain when chewing Clicking or popping sensation in the joints Headache\nA doctor will diagnose TMJD by taking a medical history, reviewing symptoms, conducting a physical exam, and discussing any recent oral trauma or recent dental procedures. The patient’s bite pattern will also be evaluated to look for misalignment and X-rays could be ordered to check the teeth, joints, and bone structures.\nTreatment options for TMJD varies based on the symptoms but may include:\nArthocentisis – procedure to flush debris causing inflammation from the joint Behavior modification or stress management to stop habits like clenching/grinding the teeth; use of a night guard while sleeping may be recommended Medication to relive pain, swelling, and inflammation Splints to better align the jaw, muscles, and ligaments Surgery to correct jaw abnormalities Tooth/Teeth Issue\nPain when chewing could also stem from an issue with one or more tooth. Common tooth related causes for chewing difficulty include:\nTooth Decay or a Cavity: Cavities are areas of where decay has permanently damaged the tooth enamel creating a pit or hole where food and debris can collect resulting in pressure and pain. Cavities are generally corrected with dental fillings. Tooth Abscess: An infection of the inner tooth pulp, an abscess can result in severe pain. Root canal procedures are often needed to remove the infected pulp tissue and restore the tooth. Periodontal Disease: Pain when biting down could be due to gum disease. Gum disease can lead to receding gums, exposed tooth roots, spaces between the teeth, and loose teeth. Early periodontal disease may be corrected with a deep cleaning (scaling and planing) procedure but if left to progress, surgical interventions may be needed. Cracked Tooth: A cracked tooth is not always obvious (visible) beyond pain when chewing. Severe fractures may be visible or show up on X-ray but hairline fractures are often undetectable. Treating a cracked tooth will vary based on the severity but options include bonding, crowns, and veneers.", "pred_label": "__label__POS", "pred_score_pos": 0.6212509274482727} +{"content": "Abstract:\nUnderstanding the spatial variability of reservoir properties in tight gas sandstones can significantly reduce uncertainties in reservoir characterization. This study focuses on two outcrops of Upper Carboniferous (Westphalian D) fluvial sandstones in the southern part of the Lower Saxony Basin, NW Germany, which are analogues for tight, gas‐producing reservoir rocks at fields in the north of the basin. Large‐scale differences in reservoir quality occur between the two outcrops which are separated by a distance of approximately 15 km and by 600 m of stratigraphy. Smaller‐scale heterogeneities in the form of channel geometries occur within individual fluvial cycles, as evidenced in a 30 m (high) by 150 m (long) porosity‐permeability profile at one of the outcrops studied.\nIn the Woitzel quarry, lower Westphalian D deposits consist of fining‐upwards cycles of channel and bar sandstones with intercalated floodplain sediments and coal seams. In abandoned quarries at the Hüggel location, upper Westphalian D strata are composed of grey and red coloured sandstones which suggest deposition in a fluvial – alluvial plain environment under increasingly arid conditions.\n... mehr\nReservoir quality is higher in the upper Westphalian D sandstones at Hüggel (permeability: up to 1 mD; mean porosity: 19%) than in the lower Westphalian D sandstones at Woitzel (permeability: <0.1 mD; mean porosity: 15%). Due to the high degree of compaction of the upper and lower Westphalian D deposits (intergranular volumes of 21.9% and 19.4% respectively) and the high proportions of pseudomatrix, porosity in these sandstones is mainly secondary with up to 80% microporosity. Reservoir quality is in general higher in the upper Westphalian D sandstones where kaolinite is present. In contrast, intense illitization has degraded the reservoir quality of the lower Westphalian D sandstones.\nA positive correlation between permeability and grain size is exhibited by the kaolinite‐bearing upper Westphalian D sandstones. No such correlation is evident in the illite‐bearing lower Westphalian D sandstones, unless samples with permeabilities of <0.01 mD are excluded from the correlation. However, such a low permeability cut‐off is not related to sorting, grain size or authigenic quartz cementation.\nAt a small scale, permeability varies laterally by two orders of magnitude from 0.001 mD to 0.1 mD in a single, approximately 3 m thick tight sandstone bed over a distance of 150 m. Repeated, centimetre‐scaled fining‐upwards grading and bed‐internal erosion contribute to lateral variations in reservoir flow characteristics.\nIntegrated studies of the depositional environment, diagenesis and sedimentary geometries of the deposited units are a key to the understanding of heterogeneities in tight fluvial sandstones and thus to the successful development of Upper Carboniferous reservoirs in the Lower Saxony Basin and elsewhere.", "pred_label": "__label__POS", "pred_score_pos": 0.5071436166763306} +{"content": "We make every attempt to retain trees in the streets and parklands for as long as possible and in the best possible condition.\nMany residents request the removal of a tree because it sheds berries, nuts, leaves or other material. While we acknowledge that trees will shed, this is seen as a natural occurrence. As such we cannot remove a tree on this basis.\nWhen can I request a tree removal?\nA request can be made when a tree is:\ndead or in severe decline a risk to the community that cannot be mitigated through management techniques identified as part of an asset renewal program.\nTrees will only be removed in accordance with relevant guidelines and procedures.\nWe will engage with the community on street and park tree removal decisions in accordance with the community engagement framework.\nRequest a tree inspection\nYou can request a tree inspection via our online form.", "pred_label": "__label__POS", "pred_score_pos": 0.972818911075592} +{"content": "Over the last 60 years we have seen a significant rise in metabolic disease, especially type 2 diabetes. In the same period, the emergence of electricity and artificial lighting has allowed our behavioural cycles to be independent of external patterns of sunlight. This has led to a corresponding increase in sleep deprivation, estimated to be about 1 hour per night, as well as circadian misalignment (living against the clock).", "pred_label": "__label__POS", "pred_score_pos": 0.9994636178016663} +{"content": "Sept 23 (Reuters) – Euro zone enterprise exercise grew at its weakest tempo in 5 months in September as curbs to restrict the Delta variant of coronavirus hit demand and supply-chain constraints pushed enter prices to a greater than two-decade excessive, a survey confirmed on Thursday.\nRegardless of every day an infection charges slowing considerably over the previous month, most remaining restrictions are unlikely to be lifted anytime quickly in main economies, together with Germany and France, on considerations over how the pandemic would possibly develop within the months forward. read more\nIHS Markit’s Flash Composite Buying Managers’ Index, a great gauge of total financial well being, fell to a five-month low of 56.1 in September from 59.0 in August.\nThough it stayed above the 50 stage separating development from contraction for the seventh consecutive month, it was properly beneath a Reuters ballot estimate of 58.5.\n“September’s flash PMI highlights an unwelcome mixture of sharply slower financial development and steeply rising costs,” stated Chris Williamson, chief enterprise economist at IHS Markit, in an announcement.\n“Progress appears more likely to weaken additional in coming months if the value and provide headwinds present no indicators of abating, particularly if accompanied by any rise in virus instances as we head into the autumn.”\nA sub-index monitoring enter prices hit 70.5, its highest in additional than 20 years. That implies provide distortions – one of many major drivers of costs all through the globe over previous months – are removed from resolved and the pattern of upper inflation is right here to remain no less than for just a few months to return. read more\nCertainly, optimism about future output fell to an eight-month low. That contrasts with enhancing client confidence, in line with the most recent European Fee information.\nA PMI overlaying the bloc’s dominant service trade tumbled to 56.3 in September from 59.0 in August, its lowest since Could and considerably beneath the Reuters ballot forecast of 58.5.\nNew enterprise – a measure that tracks demand within the sector – expanded at its slowest tempo in 5 months.\nAdditionally, the manufacturing PMI declined to 58.7 from 61.4 in August, its lowest since February and beneath the Reuters ballot forecast of 60.3. An index measuring output that feeds into the composite PMI fell to 55.6 from 59.0, the weakest in eight months.\nWeakening demand led corporations to rent on the slowest tempo in six months. In the meantime, backlogs of labor expanded at a sturdy tempo once more, signaling worsening provide constraints.\nReporting by Indradip Ghosh; Modifying by Hugh Lawson\nOur Requirements: The Thomson Reuters Trust Principles.", "pred_label": "__label__POS", "pred_score_pos": 0.6145185828208923} +{"content": "In the final lecture in his series on the twelve ‘minor’ prophets of Israel, the Trei Asar, David examines the prophets who lived during the period after Israel’s return to Zion, following the Babylonian exile, namely:\nHagai\nZechariah\nMalachi.\nWith their unique post-exilic messages, these three prophets addressed the concerns of a population grappling with rebuilding Jerusalem after generations away. Some of the ideas expressed in their powerful prophetic books include:\nthe need to rebuild the leadership of Israel\nthe importance of building a new temple in Jerusalem\na call to do teshuva\nrebuilding oneself through dialogue with God\nthe failure of previous generations\ncreating righteous leadership\necstatic visions\nthe implications of changing geopolitical realities\nfalse prophecy\nthe end of the prophetic epoch.\nDavid closely examines key passages of these biblical texts, explaining their meaning and the implications of their messages.\nAs always, he places the prophets, their lives, and their words in historical context. He also emphasises the lasting importance of their ideas for the Jewish people as a nation and for us all as individuals.\nThis second instalment of David’s series on the Trei Asar, the twelve “minor” prophets, explores the lives and books of:\nOvadiah (Obadiah),\nYonah (Jonah), and\nMichah.\nDavid examines the historical contexts of all three prophets and how they are reflected in the texts. He also discusses the key themes in these three prophetic books, including:\nnational and individual teshuvah\nthe destruction of the Kingdom of Israel\nfalse prophets and prophecy\nEdom and its spiritual and geo-historical connections\ndestinations of exile\nmessianic visions\nthe importance of ethical and just behaviour.\nIn exploring these themes, David also delves into the words of these prophets. He examines, line-by-line, some of the key passages of the books and reveals the remarkable power and substance of these fundamental sacred works.\nThe houses of David and Omri in the kingdoms of Judah and Israel are the focus of this episode. David provides a geo-political picture of the region at this time, including what was happening with Aram, Moab, Edom and Assyria as well as the prophets Elijah and Elisha and the spread of the Baalist cults. As he warns, this lecture is complex – with a number of kings of the same name in different kingdoms at different times. It also contains a lot of battles, assassinations, and general bloodshed.\nThis website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish.AcceptRead More\nPrivacy & Cookies Policy\nPrivacy Overview\nThis website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.6663418412208557} +{"content": "Basic or comprehensive metabolic test: Commonly part of a routine physical, this test measures the body’s blood sugar, kidney function, and other vital organ function. Fasting is usually required for 10-12 hours before the test.\nCan you eat before a comprehensive metabolic panel?\nIf fasting is requested by your physician, it means no eating or drinking for at least eight hours before the test. This may be critical to get accurate results. A metabolic panel can measure the function of these important indicators of whole health: Kidney and liver function.\nDoes comprehensive metabolic panel require fasting?\nBasic or comprehensive metabolic tests: Tests for blood sugar, electrolyte balance, and kidney function. Typically, people will be asked to fast for 10 to 12 hours before having one of these tests.\nCan you drink water before a comprehensive metabolic panel?\nFasting means you don’t eat or drink anything but water usually for 8 to 12 hours beforehand. If your appointment is at 8 a.m. and you’re told to fast for 8 hours, only water is OK after midnight.\nWhat happens if you don’t fast before a blood test?\nWhat happens if I don’t fast before a blood test? If you don’t fast before a test that requires it, the results may not be accurate. If you forget and eat or drink something, call your doctor or lab and ask if the test can still be done. They can then tell you if you need to reschedule your test.\nWhat can a comprehensive metabolic panel detect?\nA comprehensive metabolic panel is a blood test that measures your sugar (glucose) level, electrolyte and fluid balance, kidney function, and liver function. Glucose is a type of sugar your body uses for energy. Electrolytes keep your body’s fluids in balance.\nAre cholesterol tests affected by food eaten the day before?\nFasting for 10 to 12 hours before a cholesterol test ensures that a single food or meal does not affect the outcome of the test. However, if you ate a cheeseburger every day, that probably would affect your numbers. Cholesterol levels are affected by what you eat over time.\nIs 10 hours fasting enough for lipid profile?\nThis test may be measured any time of the day without fasting. However, if the test is drawn as part of a total lipid profile, it requires a 12-hour fast (no food or drink, except water).\nWhat does an abnormal comprehensive metabolic panel mean?\nThese help your body balance its fluids. They also help control your heartbeat and how your muscles and your brain work. Abnormal results could mean you have heart disease or kidney disease, or that you’re dehydrated.\nWhat are normal comprehensive metabolic panel results?\nCreatinine: 0.6 to 1.3 mg/dL (53 to 114.9 µmol/L) Glucose: 70 to 100 mg/dL (3.9 to 5.6 mmol/L) Potassium: 3.7 to 5.2 mEq/L (3.70 to 5.20 mmol/L) Sodium: 135 to 145 mEq/L (135 to 145 mmol/L)\nCan you have coffee before a blood test?\nEven if you drink it black, coffee can interfere with blood test results. That’s because it contains caffeine and soluble plant matter, which might skew your test results. Coffee is also a diuretic, which means that it will increase how much you pee.\nDoes what you eat the night before affect blood test?\nMcKnight also mentioned the food or drinks you consume the day or night before a blood test does not impact your test results, unlike what you eat or drink the morning of your test. “It’s recommended that you avoid coffee and other liquids during your fast,” McKnight said.\nHOW DOES NOT fasting affect your cholesterol test?\nThe truth is, your cholesterol can be tested without fasting. In the past, experts believed fasting ahead of time produces the most accurate results. This is because your low-density lipoproteins (LDL) — also known as “bad” cholesterol — may be affected by what you’ve recently eaten.\nCan you drink lemon water while fasting?\nIs lemon water safe to drink while fasting? In strict terms, consuming any number of calories will break a fast. That said, human metabolism is complex and doesn’t operate like an on-and-off switch ( 2 ). In reality, drinking plain lemon water, which contains minimal calories, is unlikely to affect your fast.\nCan you chew gum while fasting for a blood test?\nChewing gum, even sugar-free gum, should be avoided when fasting for a blood test. This is because it can speed up digestion, which can affect results.\nIs 8 hours enough for fasting blood work?\nHow long do I have to fast before the test? You usually need to fast for 8–12 hours before a test. Most tests that require fasting are scheduled for early in the morning. That way, most of your fasting time will be overnight.", "pred_label": "__label__POS", "pred_score_pos": 0.6023097038269043} +{"content": "Recognizing that the impact of the COVID pandemic has been significant on our region, area residents, businesses, foundations, and organizations have responded generously by donating more than $361,000 to the Parkersburg Area Community Foundation's (PACF) Safety Net Fund and Hunger Fund.\nAs a result, since March, the PACF has awarded $302,000 in grants to area nonprofit organizations to address COVID-19 related needs, including $43,990 in new grants in its sixth round of pandemic response. Several of the recent grants were awarded through partnership with the Sisters Health Foundation (noted with an *). Agencies that received funding during the PACF's sixth round of grants include:\nActors Guild of Parkersburg - $5,000 in operating support to address revenue loss from canceled performances. Boys and Girls Club of Parkersburg - $5,000 to support programs and services for children and youth during school closures.* Community Resources - $1,300 for support for the Doddridge County food pantry. Community Resources - $10,000 for rent, mortgage, and utility assistance to individuals impacted by COVID-19.* Doddridge County Family Resource Network - $250 for the purchase of cleaning products to distribute to Doddridge County residents in need. Downtown PKB - $5,000 in operating support to address revenue loss from cancellation of events and fundraisers and to ensure continuation of programming. EVE, Inc. - $4,000 in operating support to address revenue loss from canceled fundraisers and ensure continuation of programming for victims of domestic violence.* Gilmer County Family Resource Network - $1,000 in operating support to address revenue loss from thrift store. Living Heritage Museum/New Era One Room School - $340 to address revenue loss and assist with facility heating costs. Normantown Historical Community Center - $1,100 to purchase food for the food pantry and supplies to make masks for schools and community organizations. Parkersburg YMCA - $2,500 for technology needs related to childcare services for school-aged children due to school closures and virtual learning. Roane County Committee on Aging - $2,000 for operating support for the organization's Amma and Reedy satellite sites.* The Gathering Church - $1,000 for food purchases for food delivery program. Washington United Methodist Church - $500 to purchase a freezer for new pantry to increase food access during the pandemic. West Virginia Nonprofit Association - $1,000 to support memberships for nonprofit organizations from the PACF service area who are facing financial hardship due to COVID-19. Wood County Senior Citizens Association - $1,500 to purchase shelving and supplies for the Household Goods Pantry to meet the needs of seniors for hygiene and cleaning products.* Wood County Society - $2,500 in operating support to address revenue loss and ensure continuation of programming.\nThe PACF is committed to granting 100% of donations received for COVID-19 relief back into the region. Organizations that have needs related to COVID impact are encouraged to contact the Foundation at info@pacfwv.com or 304-428-4438 to inquire about support.\nDonations to support the PACF's Hunger Fund and Safety Net Fund are tax-deductible and greatly appreciated. To learn more about these funds and the work that the Foundation is doing to address COVID-19 in our region, visit www.pacfwv.com/COVID19.", "pred_label": "__label__POS", "pred_score_pos": 0.9888085126876831} +{"content": "To ask the Secretary of State for Business, Energy and Industrial Strategy, what assessment his Department has made of the adequacy of legislation on ensuring that toys manufactured overseas carry the address of a UK entity responsible for product safety compliance.\nAnswered on\n16 September 2021\nWhere toys manufactured overseas are placed on the UK market, a UK-based importer must ensure that their name or trade name and address are marked on the product.\nHowever, the Government recognises the challenge of third-party sales, where the retailer is based overseas. OPSS is currently conducting a review of the UK’s product safety framework, including in relation to e-commerce and supply chain responsibility, to ensure it remains fit for purpose, protects consumers, and enables businesses to innovate and grow. The Government issued a public Call for Evidence to support the review which closed on 17 June. Officials are currently reviewing the evidence received and we will publish a response in due course.", "pred_label": "__label__POS", "pred_score_pos": 0.9994456171989441} +{"content": "Creating and using the 2015 Kansai inter-regional input-output table Research leader:\nKikuo TAKABAYASHI, Professor, School of Economics, Kwansei Gakuin University\nResearch outline:\nThe inter-regional input-output table allows us to analyze the economic ripple effect caused by inter-regional trade structures and regional interdependence. By focusing on the Greater Kansai area* and by integrating the results of a preliminary survey conducted among residents and visitors to the Kansai region, we obtained a table which offers a more realistic view of the situation**. This fiscal year, we are planning to analyze the ripple effect of the tourism industry, which was hit hard by the COVID-19 pandemic.\n*Greater Kansai area includes the following eight prefectures: Fukui, Mie, Shiga, Kyoto, Osaka, Hyogo, Nara, Wakayama, Tottori, and Tokushima.\n**The input-output table targets every year whose number ends in “0” or “5”, leading to a time lag of approximately five years between the target year and the publication year. As of March 2021, we have almost finished collecting the 2015 data for every Kansai prefecture, and based on it we will create the “2015 Kansai inter-regional input-output table”.", "pred_label": "__label__POS", "pred_score_pos": 0.9913409948348999} +{"content": "Managing Third-Party Personal Injury Claims After Workplace Injuries\nMany people believe that their workplace injuries mean that they are only eligible for workers’ compensation. In reality, many injured workers also have grounds for personal injury claims against third parties that contributed to their suffering.\nAt Connors LLP, we are renowned for our extensive litigation experience. We draw on decades of combined experience to craft highly personalized and effective legal strategies designed specifically to make the most out of your compensation claim. To request a case evaluation, please complete our online contact form.\nUnderstanding The Foundations Of Third-Party Personal Injury Claims\nIn many cases, workplace injuries are not the sole fault of the employer. In cases like this, a skilled attorney can hold other parties accountable for the damages that result. For instance, if a defective table say injures a construction worker, they likely also have a claim against the table saw manufacturer. Similarly, if a truck driver loses control after a tire explodes, the tire company or the truck maintenance company may bear some of the responsibility for the crash.\nA third-party injury claim ensures that those responsible for the root causes of your injury also are held accountable both legally and financially. These cases are often hard-fought and require intimate knowledge of the law but can make a substantial difference in the resources available to you and your loved ones during recovery.\nWelcome To Our Office. Let Us Get Started.\nMany injured workers come to us at the recommendation of their workers’ compensation attorneys, particularly when multiple parties are involved in their case. We are glad to sit down with you and discuss your case at our Buffalo office: 716-852-5533.", "pred_label": "__label__POS", "pred_score_pos": 0.9512882828712463} +{"content": "Scabies outbreaks have been described in hospital settings, nursing homes, and long-term care facilities, but to our knowledge an outbreak of scabies in a neonatal intensive care unit (NICU) has not been reported previously.Reference Buehlmann, Beltraminelli and Strub\n1 –Reference Hewitt, Nalabanda and Cassell 4 We report an outbreak of scabies in the NICU of a children’s hospital, describe the diagnostic and treatment challenges in this subset of patients, and highlight the containment measures implemented to halt transmission.\nAn outbreak of scabies occurred from April through July 2016 in the 104-bed, level 4 NICU of an academic children’s hospital. The index patient was a 35-week preterm newborn admitted to the NICU due to complications of prematurity. On hospital day 54, the infant developed papules and pustules on his right arm. The rash was initially thought to be contact dermatitis, but the infant developed additional papules and pustules on the abdomen, legs and back. Due to the progression of the lesions, dermatology was consulted. On hospital day 61, skin scrapings revealed the presence of a mite, confirming the diagnosis of scabies. Failure to initially consider scabies in the differential diagnosis of the rash resulted in a 7-day delay in diagnosis, isolation, and treatment. The infant was placed on contact precautions upon diagnosis and treated with 5% permethrin lotion.\nA contact investigation was performed by the infection prevention department, utilizing the following definitions. A “confirmed case” of scabies was defined as identification of mites by skin scraping and/or clinical examination. A “probable case” was defined as a person with an epidemiological link to a case and signs and symptoms consistent with scabies. Healthcare personnel (HCP) with skin-to-skin contact or close contact on multiple occasions to the index patient, and the neonates cared for by these HCP were considered exposed to scabies. Incubation period was 2–8 weeks. The attack rate was calculated by dividing the number of confirmed and probable cases by the number of exposed individuals.\nThe parents of the index patient were identified as the source. All exposed HCP and their household contacts underwent preemptive treatment with 5% permethrin. Of the 139 exposed neonates, 39 were ≥2 months old and 100 were <2 months old. All 39 infants ≥2 months old were treated with 5% permethrin. The 100 exposed infants <2 months old were not treated due to the lack of safety data for use of 5% permethrin in this age group. These infants were placed on contact precautions for the remainder of their 8-week incubation period. The care areas for the index case and exposed patients were thoroughly cleaned, and all bed linens and clothing were washed with hot water. Common family waiting areas were also cleaned. During the initial contact investigation, none of the identified exposed HCP, their household contacts, or exposed infants developed clinical signs of scabies. We later identified 3 secondary cases of scabies. This included 2 nurses and 1 occupational therapist who developed scabies 6 weeks after contact with the index case. They were not identified as exposures during the initial investigation and had not received prophylaxis. No further cases were diagnosed during the 6-month follow-up period. This resulted in an overall attack rate of 2%.\nThis outbreak highlights the challenges encountered in the containment of a nosocomial outbreak of scabies in a NICU. In this outbreak, lack of familiarity with the clinical presentation of neonatal scabies led to a 7-day delay in diagnosis. Neonatal scabies typically presents with pustules, vesicles, or papules involving the face, scalp, palms, and soles. This presentation contrasts with that in adults, in whom intertriginous papules and burrows are classically found. The characteristic pruritus may be absent in neonates contributing to delayed diagnosis and ongoing transmission.Reference Hurwitz\n5 –Reference Wilson, Mandell, Bennett and Dolin 7 Failure to consider scabies as the cause of a rash has been previously identified as a factor in the propagation of nosocomial outbreaks.Reference Buehlmann, Beltraminelli and Strub 1 –Reference Vorou, Remoudaki and Maltezou 3 Once considered, early and rapid diagnosis can be achieved by obtaining skin scrapings to identify the mite.Reference Leung and Miller 8 Therefore, to facilitate prompt diagnosis and prevent spread in the NICU, the possibility of scabies should be entertained for any infant, HCP or visitor with an unexplained rash.Reference Nanda, Reddy, Ramji and Pandhi 9\nDuring our investigation, we identified important gaps in our surveillance process. We found 3 secondary cases of scabies who had had contact to with the case patient but were not initially treated because they were missed during the initial investigation. Also, 1 HCP did not routinely work in the NICU, which hampered identification or notification of the exposure. Ensuring that all potential contacts to a case have been identified can be challenging when HCP rotate to different areas within a unit or when non–unit-based HCP provide ancillary services. Reviewing medical records for orders placed to ancillary services may help accurately identify exposed non–unit-based staff. Additionally, targeted communication to key personnel, especially those responsible for staffing, can assist in addressing this potential gap in ascertainment of contacts. This is essential because continued propagation of an outbreak can place a substantial financial burden on an institution.Reference Dik, Dinkelacker and Verner\n10 Although we did not perform a formal cost analysis in this outbreak, our institution incurred costs related to environmental cleaning and disinfection, treatment of neonates and HCP, use of isolation precautions, and hours spent on institutional control measures.\nIn summary, HCP should familiarize themselves with the presentation of neonatal scabies and have a low threshold to evaluate, isolate, and treat neonates with a suspicious rash. A multifaceted approach involving clinicians, hospital administration, and environmental services is essential in preventing nosocomial scabies in the NICU setting.\nAcknowledgements\nNone.\nFinancial support\nNo financial support was provided relevant to this article.\nConflicts of interest\nAll authors report no conflicts of interest relevant to this article.", "pred_label": "__label__POS", "pred_score_pos": 0.664898693561554} +{"content": "Many individuals living with cancer are protected from COVID-19. However, some people living with cancer have increased risk of hospitalisation and mortality from COVID-19.\nVaccination and boosters are recommended for individuals who are on anti-cancer treatments. However, some individuals may have a less effective immune response and lower antibody levels. Research is required to understand the protection provided by antibodies generated following COVID-19 infection and vaccination.\nIt is important to safeguard, monitor and protect people with cancer. In direct response, the National COVID cancer survey was launched in September 2021 across England. The survey will provide crucial insights to aid wider efforts to safeguard, protect and monitor vulnerable groups and those living with and beyond cancer.", "pred_label": "__label__POS", "pred_score_pos": 0.9999094009399414} +{"content": "Without the trust that mAssets should be pegged to oracle prices, mAsset prices could theoretically diverge from oracle prices. Unlike minting liquidation which can create buying pressure to drive prices upwards, the Mirror protocol can only drive downward pressure to the minimum collateral price of an mAsset. For instance, if the MCR of an asset is 150% and the oracle price of XXX is $100, then the price of an mXXX could, in theory, reach $150. However, once the price of mXXX is greater than $150, then arbitrageurs can simply mint mXXX with $150 worth of collateral, sell the mXXX for $160, and forego the collateral. Therefore, the theoretical maximum price of mXXX would be $150. If, in practice, mAsset prices did drift significantly higher than oracle prices, governance could be used to solve this by creating incentives to mint and sell assets. For instance, the MCR could be lowered in order to reign in mAsset prices or negative selling fees could be used to incentivize users to mint assets and sell them in the market. Changing governance, however, would require a proposal and the collective agreement of MIR stakers.", "pred_label": "__label__POS", "pred_score_pos": 0.6078327894210815} +{"content": "OBJECTIVE\nWe describe the baseline characteristics and complications of individuals with influenza in the US FDA's Sentinel System by antiviral treatment timing.\nDESIGN\nRetrospective cohort design.\nPATIENTS\nIndividuals aged ≥6 months with outpatient diagnoses of influenza in June 2014-July 2017, 3 influenza seasons.\nMETHODS\nWe identified the comorbidities, vaccination history, influenza testing, and outpatient antiviral dispensings of individuals with influenza using administrative claims data from 13 data partners including the Centers for Medicare and Medicaid Services, integrated delivery systems, and commercial health plans. We assessed complications within 30 days: hospitalization, oxygen use, mechanical ventilation, critical care, ECMO, and death.\nRESULTS\nThere were 1,090,333 influenza diagnoses in 2014-2015; 1,005,240 in 2016-2017; and 578,548 in 2017-2018. Between 49% and 55% of patients were dispensed outpatient treatment within 5 days. In all periods >80% of treated individuals received treatment on the day of diagnosis. Those treated on days 1-5 after diagnosis had higher prevalences of diabetes, chronic obstructive pulmonary disease, asthma, and obesity compared to those treated on the day of diagnosis or not treated at all. They also had higher rates of hospitalization, oxygen use, and critical care. In 2014-2015, among those aged ≥65 years, the rates of hospitalization were 45 per 1,000 diagnoses among those treated on day 0; 74 per 1,000 among those treated on days 1-5; and 50 per 1,000 among those who were untreated.\nCONCLUSIONS\nIn a large, national analysis, approximately half of people diagnosed with influenza in the outpatient setting were treated with antiviral medications. Delays in outpatient dispensed treatment were associated with higher prevalence of comorbidities and higher rates of complication.", "pred_label": "__label__POS", "pred_score_pos": 0.7921954393386841} +{"content": "As we head into another fall during the pandemic, returning employees to the workplace requires both vigilance and flexibility to navigate uncharted territory. In this webinar, Verrill Employment & Labor Attorneys Rob Brooks and Liz Johnston will discuss legal issues for employers at various stages of returning to the workplace, including those working in a “hybrid” model. The discussion will also include the latest guidance and considerations related to federal vaccine requirements for private-sector employees, as well as health care workers and federal contractors. Attendees will gain insights on navigating their plans for a smooth and safe return to the workplace and best practices for the workplace among the latest COVID-19 developments.\nThe webinar is free, all you need to do is register. Join us on Thursday, Oct. 14 at 10 a.m. for this free webinar.\nThis will be held virtually on Zoom. A link to participate will be sent with your email confirmation.", "pred_label": "__label__POS", "pred_score_pos": 0.9010120034217834} +{"content": "Happy Principal Appreciation Week January 24-30 Great leaders harness personal courage, capture the hearts and minds of others and empower new leaders to make the world a better place. -Maxine Driscoll\nThroughout each school year, our wonderful principal and assistant principal assume the commitment to lead our students to a successful future. They support and guide quality teachers and staff, resulting in safe and productive learning environments for our students. Teachers rely on them to ensure they have the necessary resources to provide engaging and enriching lessons so that each student has the opportunity can learn. Principals truly guide academic success. Our principals work diligently to represent our community. The needs of the community are reflected in the passion our principals instill into our teachers and staff, who strive to meet the academic and social-emotional needs of each student. Our principals listen and learn with parents and students each and every day.\nPrincipals are among the hardest working, yet often least recognized individuals in education. Principals set the academic tone for their schools, and it is their vision, dedication, and determination that provide the mobilizing force for achieving student success.\nMrs. Castillo and Mr. Birge serve as role models for our entire community every day! We are excited to hear about Governor Northam's proclamation and wish them a wonderful week ahead.", "pred_label": "__label__POS", "pred_score_pos": 0.5826069116592407} +{"content": "In the last decade, PSA was all we had. Fortunately, in 2014, that's not the case anymore. The following are tests which can complement the PSA in decision making about whether a prostate biopsy is really needed:\n1) PHI (prostate health index) - blood test\n2) 4Kscore - blood test\n3) PCA3 - urine test\nThere are also various calculators based on PSA, physical exam results, and age which assess the risk of cancer. These include:", "pred_label": "__label__POS", "pred_score_pos": 0.9999052286148071} +{"content": "Feedforward\nPosted September 5, 2020on:\nI had to dive deep into my Diigo archive for this one. It was this recent tweet that sparked my search.\nThe tweeter generously shared her own Diigo-based links to feedforward.\nMy own search was a single JISC article that was first published in December 2013 and then updated in March 2016. So the concept is not new.\nIt is, however, different in mindset and orientation. It is based on the growth of the person receiving it, not the ego and judgement dispensed by the giver. It is a longer term strategy that focuses on future work.\nIn hindsight, I could have used this concept and practice in a course I facilitated earlier this year. I gave my students two assignments that were tightly linked and the second depended heavily on making improvements to the first. Instead of simply focusing on feedback, I should have created the expectation of feedforward instead.", "pred_label": "__label__POS", "pred_score_pos": 0.7255662679672241} +{"content": "Blockchain technology and smart contracts are significant innovations. However, the technology is only as secure as the code written for it. Trader Joe is one of the blockchain projects that, with the help of multi-auditing, avoided a potential catastrophe due to a code vulnerability.\nTrader Joe Gets Multiple Code Reviews, But....\nIt is good to see more DeFi projects undergo code reviews to ensure their project will keep clients' funds safe. As most of these solutions are decentralized and trustless, the code must hold up under pressure and not contain any vulnerabilities. I am glad to see more audits happening, although everyone needs to remember they are not a guarantee for safe and secure code, unfortunately,\nIn the case of Trader Joe, the security audits themselves were rather interesting. Even though the team has undergone more than one of these audits, it appeared most of the verification procedures overlooked one crucial vulnerability. I can understand it is difficult for auditing firms to look at everything and wonder if it works as intended, although when multiple parties miss the same issue, something doesn't appear right.\nPer the explanation, there was a vulnerability in the MasterChefJoeV2 contract. Suppose an attacker took a flash loan and deposited tokens eligible for double rewards. In that case, they could emergency withdraw them, deposit a single token back, and harvest the bonus rewards as they would have with the total amount of initial tokens. That is a significant vulnerability and one that can have severe consequences. Furthermore, if multiple people exploited that option, double rewards would be issued to users who do not provide the necessary liquidity.\nAlthough the TraderJoe team removed the double rewarder contracts, it is still a strong wake-up call. With $25,000 in rewards at stake, pulling the plug is the option I would take as well. Interestingly, this issue was discovered by the SushiSwap team and not an auditing firm. However, TraderJoe has confirmed they will undergo a new audit to re-evaluate the entire protocol's security measures.\nWhy Would SushiSwap Do This?\nFor those unfamiliar, SushiSwap is one of the biggest decentralized exchanges in the world. The protocol initially aimed to compete with Uniswap, although it is challenging to dethrone the undisputed king of decentralized trading. Even so, SushiSwap is a successful platform and a platform I enjoy using for some of my tradings. Competition among DEXes is a good thing, as it fuels ongoing innovation and improvements.\nAs Trader Joe is a DEX and lending platform, it is — in theory — a competitor to SushiSwap. However, if any cog in the DeFi machine fails, the impact on other projects can be rather severe. Keeping all projects safe from harm benefits the broader industry, including services that would otherwise be competitors. Moreover, Trader Joe is an up-and-coming platform that is gaining a lot of Total Value Locked on the Avalanche blockchain, making it a platform worth supporting, in my view.\nMoreover, the open-source nature of smart contracts makes them easy to access and read. Therefore, it is in every developer's best interest to look at how others put their code and functions together. If something seems amiss, alerting the code creator is the courteous thing to do. I find it heartwarming that SushiSwap decided to alert Trader Joe about this issue, even though they had no obligation to do so.\nThe HashEx Angle\nAs one of the companies auditing Trader Joe, HashEx looked at the code for this project and documented a few issues in their initial audit report. The issue affecting the smart contract and double rewards was not discovered at the time. SushiSwap’s team was already notified about the issue, allowing them to offer a helping hand. HashEx offered support and advice regarding the severe bugs and recommendations on what to address.\nThe HashEx team conducted a preliminary smart contract audit for TraderJoe in August 2021. The team notes three high-severity issues and several code improvements to be made. As is courtesy in this industry, the firm included several recommendations to ensure these bugs coil not become critical flaws if left unaddressed.\nFollowing the discovery of the vulnerability, the team looked back at the code and confirmed no one had any time to exploit the vulnerability before Trader Joe removed the double rewards. Moreover, the EmergencyWithdraw function was used three times for small amounts, confirming no funds have been stolen. However, it is evident that multiple audits from several independent companies — something that is largely accepted in the DeFi space — are an absolute must for any self-respecting project.\nConclusion\nIn the end, the vulnerability has been addressed, and no funds have been lost. Trader Joe and its users are happy and can continue using Avalanche's service without any issues. The double rewards are no longer in play, although removing them was the only viable option to guarantee safety for all involved parties.\nI'm glad to see such a quick resolution to this matter, and it highlights the need for multi-auditing. Having multiple sets of eyeballs go through code is essential to ensure the code works as intended and cannot be exploited in any manner. It is also a severe warning to other DeFi projects that either refuse or neglect audits, of which there are many. Having code vetted by official auditing companies or developers is essential to prevent any future mishaps.\nCreate your free account to unlock your custom reading experience.", "pred_label": "__label__POS", "pred_score_pos": 0.9480454325675964} +{"content": "Supplementary Material for: Phenotype Discordance between Primary Tumor and Metastasis Impacts Metastasis Site and Outcome: Results of WSG-DETECT-PriMet\ndatasetposted on 15.12.2020, 10:58 by Kolberg-Liedtke C., Wuerstlein R., Gluz O., Heitz F., Freudenberger M., Bensmann E., duBois A., Nitz U., Pelz E., Warm M., Ortmann M., Sultova E., Brucker S.Y., Kates R.E., Fehm T., Harbeck N.\nTumor biological factors of breast cancer (BC) such as hormone receptor (HR) status, HER2 status, and grade can differ in the metastatic cascade from primary to lymph node (LN) metastasis and to distant metastatic tissue. Systematic data regarding therapeutic consequences are yet limited. Introduction: We conducted a prospectively planned, retrospective cohort study comparing BC phenotype in tissue from primary tumors (PTs), locoregional LN metastases, and disease recurrence (DR). HR and HER2 as well as tumor grade in PTs and DR were obtained by a database search. No centralized biomarker testing was performed. The impact of changes in tumor biological factors on post-recurrence survival (PRS) and overall survival was analyzed. Methods: PriMet comprises 635 patients (LN tissue in 142 patients). Discrepancies for HR or HER2 status between PT and DR were observed in 18.7 and 21.6% of cases, respectively. For HR status, positivity of PT and negativity of DR was seen more often (13.2%) than vice versa (5.5%). For HER2 status, negativity of the primary and positivity of DR was seen more often (14.9%) than vice versa (6.7%). Discordance was more often observed between PT and LN metastasis compared to LN versus DR. However, numbers were small. Compared to concordant non-triple-negative (TN) disease, concordant TN disease showed significantly inferior PRS. Results: We demonstrate receptor discordance to occur relatively frequently between PT, LN metastasis, and DR and to impact patient prognosis. However, clinical consequences of receptor discordance need to be drawn with caution considering clinical aspects as well as tumor biology. Conclusion:", "pred_label": "__label__POS", "pred_score_pos": 0.5189880132675171} +{"content": "A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.The file type is\napplication/pdf.\nT he cardiovascular system is a complex arrangement of hydraulic, yet living, components. The complexity of this system may make it difficult for students to see the \"forest\" instead of the \"trees.\" To better explain the dynamics of cardiovascular function and control, an analogy has been drawn to the operation of a city water supply. In cities that use a water tower, fresh water is pumped up into the tower from a river or other source. The tower serves as a pressure reservoir for providingdoi:10.1152/advances.2000.24.1.43 pmid:11209564 fatcat:wvz56jhixfbe7fruxv75jq3ub4", "pred_label": "__label__POS", "pred_score_pos": 0.5884789228439331} +{"content": "Sesame is one of the most versatile crops. Sesame seeds are a reservoir of healthy fats and protein. The oil extracted from sesame seeds is a premium cooking oil. It's often acknowledged as \"the queen of oils\" due to its high concentration of antioxidants. The September 7 th, 2021 Sustainable, Secure Food Blog explores more about sesame seed cultivation.\nAccording to blogger Gurjinder Baath, there are several reasons farmers choose to grow sesame:\nDue to its short growing season, it can be easily added to various crop rotations.\nSesame requires lower resources and offers more return (less risk) than other crops.\nFarm equipment that farmers already have can be used for growing sesame.\nSesame is known for its heat, drought, disease, and insect tolerance. It is also less susceptible to economic damage from wild hogs, deer, or birds.\nSesame has low water use during the drying phase that leads to more soil water storage for the subsequent crop in double-cropping systems.\nThe brittle sesame residue controls soil erosion like higher residue crops, without the need for excess residue bailing equipment.\nResearchers at Oklahoma State University, where Baath works, have been investigating the potential impacts of different air temperatures on sesame growth, yield, and physiology. They hope to define suitable regions for sesame cultivation as well as develop adaptation strategies for offsetting the impacts of future climate change.\nFuture research will study the factors responsible for temperature tolerance in sesame. Genetic evaluation of sesame is necessary to identify varieties capable of maintaining reproductive development under high temperatures. This will provide a broader geographic adaptation and sustain crop yields under current and future climates.", "pred_label": "__label__POS", "pred_score_pos": 0.9301495552062988} +{"content": "Supplies & Equipment\nOur healthcare cleaning training program details the most efficient and effective technology to be used in the healthcare environment. We are dedicated to providing chemicals, tools, and equipment, are not only safe, but highly proficient in allowing the end users to complete the task to a high quality.\nStandard Operating Procedures\nOur program focuses on the conduct required in the healthcare setting. It details the communication, relationships, and solutions that should be standard throughout the industry. Our healthcare cleaning training programs also outline the surveying, estimating, and pricing procedures that provides the best overall partner with healthcare organizations.\nOur healthcare janitorial training program explains in detail the importance of infection prevention and methods associated with that goal. It provides the proper systems to assist with proven cleaning methods the lower the risk of cross contamination that lead to infection. Our program outlines the concept of Universal Precautions and the correct use of Personal Protective Equipment (PPE).\nOur healthcare janitorial service training program details all associated standards to ensure a safe environment for our cleaning staff, healthcare professionals, and of course the patients. We successful equip our cleaning staff through use of a specific Bloodborne Pathogen (BBP) training program motivating employees to use the correct procedures when potentially infectious materials are present.\nOur healthcare cleaning training program provides the proper methods for cleaning healthcare specific areas, while providing the tools necessary to ensure these methods are used.\nOur healthcare cleaning training program explains the techniques associated with performing quality floor maintenance until not interrupting the care being given to patients. This ensures that staff has an environment they proud of, and provides an appearance that patients and visitors feel comfortable.\nOur healthcare cleaning training program implements a system that relieves healthcare professional of quality standards’ worries. We provide up-to-date, frequent quality inspections that are immediately communicated to the healthcare facility.", "pred_label": "__label__POS", "pred_score_pos": 0.5938659906387329} +{"content": "Conceptual Design Preliminary Design Detailed Design Technical Specifications Bill of Quantities FIDIC Book CoC Water Supply, Wastewater Plants, and Network Systems Urban Infrastructure\nWe prepare designs comprehensively and according to the corresponding stage of the project, and the form of contract selected for the enterprise. We seek to understand the technical and safeguarding issues, the client’s expectations and traditions, as well as the contractor’s abilities when preparing the designs, to minimize any complications during the construction phase, both from the client’s and from the contractor’s side.\nWe bring innovative and established practices from all over the world and integrate our norms and standards to the context specific needs. We aim to avoid adopting a typical bias in the design of water, sanitation, and urban infrastructure to circumvent quick wins. Instead, we take a more progressive stance, adopting long-term views and supporting a progressive management of the assets to be designed and implemented.\nWe offer design services based on the requirement of the projects, For example, FIDIC Condition of Contract or according to the specific standards of the development partner. Our management team has extensive experience in managing design projects following the guidelines of the World Bank, Asian Development Bank, European Union, DANIDA, KfW and JICA.", "pred_label": "__label__POS", "pred_score_pos": 0.7390460968017578} +{"content": "The Nigerian Center for Disease Control (NCDC) declared that the cholera outbreak in Nigeria had claimed the lives of up to 2,323 people across the country since its onset in January.\nOn Tuesday, September 14, the NCDC proclaimed that 46 new deaths were linked to the disease outbreak across the West African country between August 30 and September 5.\nFigures from the public health agency confirmed that a total of 69,925 suspected cases of cholera infection have already been established in over 25 states and the federal capital territory since the beginning of the outbreak.\nThe NCDC acknowledged that so far, the case fatality rate for the outbreak in the country stands presently at 3.3 %.\nIt further stated that a national multi-sectoral emergency system continues to coordinate and oversee the national response regarding the outbreak.\nAccording to health experts, Cholera is a highly virulent disease characterized in its most severe form by a sudden onset of acute watery diarrhea that can cause death due to severe dehydration.\nNigeria has been badly affected by the cholera outbreak, and this has remained quite persistent, occurring yearly. This happens most often during the rainy season and in areas with deplorable sanitation, overcrowding, lack of clean food and potable water, and areas with no good toilets where open defecation is common. These factors contribute greatly to the rapid spread of the disease.", "pred_label": "__label__POS", "pred_score_pos": 0.984917163848877} +{"content": "Perspectives\nDiversity, Equity, Inclusion, and Belonging\nDiversity, Equity, Inclusion, and Belonging are vaulting to the top of the organizational agenda. What are some of the critical success factors for DEI&B in the context of Organizational Talent, Culture, and Transformation?\nWe connected with experts from multiple disciplines, and, the voices within our team, to highlight some critical success factors to consider.\nEMERGING SUCCESS FACTORS TO CONSIDER LISTENING Putting DEI&B front and center within your VOE (voice of employee), VOC (voice of client/customer/candidate) ecosystems resulting in benchmarks, insights, perspectives, and trend analysis. THE MANIFESTO Having a manifesto that sets the context, clearly articulates the ambition, strategic pillars, from>to, journey map, point of view, commitments, and accountability for DEI&B. LEADERSHIP It starts at the top – commitment, composition, communication, and championing. PURPOSE, VALUES, EVP, COLLECTIVE AMBITION Directly embedding DEI&B into the fabric of every aspect of your talent + culture narrative. STORYTELLING Bringing real stories to life is essential to creating emotional connections with DEI&B. Looking beyond video & podcast… to storytelling as a leadership skill + ritual. TOTAL REWARDS INTEGRATION Enhanced programs to address the increase in issues related to mental, physical, and financial well-being along with practical supports like childcare. Pay equity. Incentives & rewards directly linked to DEI&B. TALENT MANAGEMENT Having a clearly articulated strategy for operationalizing DEI&B within the talent management process. Anonymization? Ambitious goals? Bias in tools/process? JOB DESIGN / FUTURE OF WORK Ensuring that job design, skills mapping, remote work, and other such factors are opening doors for DEI&B vs. creating unintended consequences. PARTICIPATION Workforce expectations have shifted with respect to workplace activism, helping set the agenda and drive results. Increased internal + external engagement is critical. INNOVATION & PERFORMANCE Drawing the direct connection between diverse + inclusive teams with organizational performance + innovation… Addressing both the ‘why’ – and the ‘how’. WE ARE MASTER STORYTELLERS. LET US HELP.\nWe help design, and produce storytelling solutions that support and drive your strategic imperatives", "pred_label": "__label__POS", "pred_score_pos": 0.9007947444915771} +{"content": "Gold exports receipts in 2020 increased to US$6.80 billion, from US$6.23 billion in 2019 on account of price increases, Bank of Ghana’s (BoG’s)2020 annual report has stated.\nThe report said the gold price increase was due to a strong investor appetite for the metal arising from the safe-haven status it enjoys in times of economic and political uncertainty.\nThe economic disruptions caused by COVID-19 influenced the price of gold, as investors rebalanced their portfolios.\nAccording to the report, the average realised price increased by 27.2%, to US$1,764.16 per fine ounce, while the volume of gold exported decreased by 14.2% to 3,854,012 fine ounces in the review year.\nCrude oil exports\nCrude oil export receipts declined by 35.2 per cent in the review year. Total export receipts in 2020 was US$2.91 billion compared to US$4.49 billion in 2019.\nThe volume of crude oil exported declined by 3.7%, to 67,458,206 barrels. The average realised price of crude oil in 2020 was US$43.15 per barrel, compared to US$64.14 per barrel in 2019, representing a decline of 32.7%.\nRestrictions on movements and the slow recovery of economies from the COVID-19 pandemic-induced shocks contributed to the price decline.", "pred_label": "__label__POS", "pred_score_pos": 0.5655986666679382} +{"content": "White Papers\nEveryone Stands to Gain – A Checklist for ESG Progress\nMaking meaningful progress on Environmental, Social and Governance (ESG) issues requires visible commitment from the highest levels.\nBoards and senior executives establish the direction and strength of organisations’ actions to become more sustainable. Clearly communicating how ESG is aligned with strategy is essential to engage stakeholders.\nThis checklist is a practical tool to help legal and governance leaders consider how their organisations are progressing along their journey to become more sustainable, from the big picture to the smaller details.", "pred_label": "__label__POS", "pred_score_pos": 0.9984461665153503} +{"content": "The project aims to comparatively study the implementation of national minimum incomes (NMI) in five Regions of Northern Italy: Piedmont, Lombardy, Autonomous Province of Trento, Veneto and Emilia-Romagna.\nThree main research lines are foreseen: providing a detailed account of the territorial contexts in which the implementation of NMI is ongoing, analysing the NMI’s implementation in the context of specific local welfare systems, identifying and explaining the main dynamics related to the NMI’s implementation in the selected local contexts.\nAfter a preliminary analysis of the existing literature and the various sources available, at least three local cases will be selected in each Region, to be investigated in-depth through a mix of quantitative and qualitative methods, through a participatory research path involving the main stakeholders, as well as social workers and beneficiaries.\nThe project intends furthering the scientific debate about minimum schemes in Italy, by assuming a specific analytical perspective focused on the implementation process considered as a social process entailing multiple roles, practices, and conceptions of poverty by different actors and specific interactions among them.\nFinancing period\n2019-2021\nWorking group\nMarco Arlotti, Stefania Sabatinelli\nFunding Institution\nMIUR – Bando Prin 2017\nPartners\nUniversità degli Studi di Trento, Università di Bologna, Università di Torino", "pred_label": "__label__POS", "pred_score_pos": 0.5785038471221924} +{"content": "Our research focuses on the adhesion mechanisms of platelets and neutrophils to sites of vascular injury/ activation. For successful adhesion, both cell types rely on activation-dependent receptors (integrins) expressed on the cell surface. We are particularly interested in the role of calcium (Ca2+) as a signaling molecule that regulates the inside-out activation of integrin receptors. Our studies combine molecular and biochemical approaches with microfluidics and state-of-the-art in vivo imaging (intravital microscopy) techniques.", "pred_label": "__label__POS", "pred_score_pos": 0.86407870054245} +{"content": "VP Bank joins UN-convened Net-Zero Banking Alliance\nRepresenting almost a quarter of global banking assets, with over 50 members from 29 countries and USD 39 trillion in total assets, the NZBA is a critical step in the mobilisation of the financial sector for climate protection. It recognises the vital role of banks in supporting the global transition of the real economy to net-zero emissions, encompassing both operational and attributable emissions (including scope 3 emissions).\nAlliance members commit to:\nSet scenario-based interim targets for 2030 or sooner for priority sectors Prioritise areas of most significant impact, i.e. the most greenhouse gas intensive and emitting sectors Annually publish emissions and emissions intensity Take into account the best available scientific knowledge Set first target(s) within 18 months of signing and report annually thereafter Disclose progress against a board-level reviewed transition strategy\nThe NZBA is convened by the United Nations Environment Programme Finance Initiative and is the banking element of the Glasgow Financial Alliance for Net Zero, chaired by Mark Carney, UN Special Envoy on Climate Action and Finance ahead of COP 26.\nVP Bank is proud to join leading peers from the banking industry in these collective efforts to reach net-zero emissions by 2050. We look forward to engaging with our clients to support them in their transition plans and accelerate action on climate.\nSustainability is integrated into VP Bank's overall group strategy 2026, and joining this alliance is fully aligned with the existing strategy and commitment to sustainability. VP Bank has already set an ambitious target of achieving net-positive impact through its offering. The Bank also set a target of achieving climate neutrality in its operations by 2026 and its approach to sustainable investing is consistently applied in the investment process and advice provided to clients.\nPaul H. Arni, Chief Executive Officer of VP Bank Group: “Joining the Alliance reflects our ambition to play an active role in creating a positive impact for society and the environment. We recognise the urgent need for action on climate change, and this is prominently reflected in our strategy 2026 in our 'Investing for Change' initiative.”", "pred_label": "__label__POS", "pred_score_pos": 0.8465358018875122} +{"content": "10:00 AM - 10:15 AM\n[AHW24-04] Identification of deep groundwater recharge system in an intermontane basin\nKeywords:Groundwater recharge, water quality, Hydrogen and oxygen stable isotope, Radiocarbon, Kathmandu Valley, Nepal\n2. The average altitude of the valley floor is 1350 m above sea level and is surrounded by the hills rising more than 2800 m. Rainfall in the basin is mostly seasonal with roughly 80% of the 1755 mm average annual total arriving between June and September during monsoon season. Groundwater samples were collected from 10 deep tube wells covering almost all parts of the valley and 2 shallow dug wells located at the central part of the valley. All the collected samples were then subjected to the analysis of major dissolved ions, hydrogen and oxygen stable isotopes and radiocarbon.\nGroundwater ion composition using Hexa-diagram showed that the deep groundwater of the Kathmandu Valley tends to be relatively young in the outer peripheral area. Meanwhile for the groundwater located in the central area tends to be older. However, for the shallow wells located at the central area, the higher values of ion composition were derived from the effect of human activities. Relatively high pMC values obtained from radiocarbon were detected from the shallow groundwater at central part of the valley and from the deep groundwater samples those were collected from the peripheral area. On the other hand, the deep groundwater at the central part of valley was observed with low pMC values.\nRelatively heavier stable isotopes of hydrogen were observed from both the deep groundwater and the shallow groundwater in the central part of the valley. Along with the pMC values, these results also suggests the possibility of vertical groundwater recharge from the shallow groundwater to the deep groundwater in central part of the valley. However, isotopically depleted groundwater recorded from the peripheral areas also concludes the recharge in this basin occurs from the mountain areas.\nAKNOWLEDGMENTS: This study was supported by the JSPS KAKENHI Grant Number is 18K11617. It was also partly supported by the Science and Technology Research Partnership for Sustainable Development Program (SATREPS, Project Manager: Professor Narendra Man Shakya and Professor Futaba Kazama) of the Japan International Cooperation Agency (JICA)/Japan Science and Technology Agency (JST).", "pred_label": "__label__POS", "pred_score_pos": 0.7218496799468994} +{"content": "Although there are still a lot questions about where the healthcare IoT security market is headed; we know that these solutions bring innovative asset management and security capabilities, according to a recent KLAS report.\nAs IT and security leaders are learning, managing medical devices isn’t a one-time event, but rather a multifaceted process that requires strong partnerships and a willingness to be nimble.\nDespite the benefits it offers – particularly in terms of patient safety – smart pump and EMR integration has sustained slow growth, according to KLAS. But that could change, depending on a few factors.\nWith remote care becoming increasingly common, CISOs no longer view medical device security as a separate entity; but rather, part of a more holistic approach, according to our expert panelists.\nAs a more diverse array of devices – with an increasingly complex architecture – enter the network, leaders need to adopt different philosophies in order to keep data secure, according to CISOs Art Ream and Ronald Mehring, who shared their thoughts during a recent discussion.", "pred_label": "__label__POS", "pred_score_pos": 0.5139626264572144} +{"content": "The Tensions between Culture and Human Rights: Emancipatory Social Work and Afrocentricity in a Global World Download\nIntroduction: Culture, Human Rights, and Social Work: Colonialism, Eurocentricism, and Afrocentricity (428.4Kb)\n1. Disrupting Popular Discourses on Ilobolo: The Role of Emancipatory Social Work in Engendering Human Rights and Social Justice (418.7Kb)\n3. Socio-Cultural Constructions of Intensive Mothering and Othermothering: Domestic Workers’ Experiences of Distance Parenting and their Conceptualization of Motherhood (406.8Kb)\n4. Misrecognition of the Rights of People with Epilepsy in Zimbabwe: A Social Justice Perspective (409.5Kb)\n5. Harmful Cultural Practices against Women and Girls in Ghana: Implications for Human Rights and Social Work (413.9Kb)\n6. The Intersection of Culture, Religion (Islam), and Women’s Human Rights in Ethiopia: Private Lives in Focus (402.3Kb)\n7. The Implications of a Patriarchal Culture for Women’s Access to “Formal” Human Rights in South Africa: A Case Study of Domestic Violence Survivors (395.7Kb)\n8. Child Marriage among the Apostolic Sects in Zimbabwe: Implications for Social Work Practice (397.1Kb)\n9. “Everybody Here Knows This, If You Want to Go to School then You Must Be Prepared to Work”: Children’s Rights and the Role of Social Work in Ghana (432.6Kb)\n11. Cultural Dimensions of HIV/AIDS and Gender-Based Violence: A Case Study of Alur and Tieng Adhola Cultural Institutions in Uganda (398.6Kb)\n12. When National Law and Culture Coalesce: Challenges for Children’s Rights in Botswana with Specific Reference to Corporal Punishment (499.5Kb)\nAccessioned2021-05-05T21:40:14Z Available2021-05-05T21:40:14Z Copyright2021 Issued2021-05 Typebook MetadataShow full item record\nAbstractA critical interrogation of the relationship between cultural practices and human rights in Africa rooted in Afrocentricity and emancipatory social work. Cultural practices have the potential to cause human suffering. The Tensions between Culture and Human Rights critically interrogates the relationship between culture and human rights across Africa and offers strategies for pedagogy and practice that social workers and educators may use. Drawing on Afrocentricity and emancipatory social work as antidotes to colonial power and dehumanization, this collection challenges cultural practices that violate human rights, and the dichotomous and taken-for-granted assumptions in the cultural representations between the West and the Rest of the world. Engaging critically with cultural traditions while affirming Indigenous knowledge and practices, it is unafraid to deal frankly with uncomfortable truths. Each chapter explores a specific aspect of African cultural norms and practices and their impacts on human rights and human dignity, paying special attention to the intersections of politics, economics, race, class, gender, and cultural expression. Going beyond analysis, this collection offers a range of practical approaches to understanding and intervention rooted in emancipatory social work. It offers a pathway to develop critical reflexivity and to reframe epistemologies for education and practice. This is essential reading not only for students and practitioners of social work, but for anyone seeking a deeper understanding of African cultures and practices. InstitutionUniversity of Calgary\nUniversity of KwaZulu Nata\nUniversity of Stavanger\nUniversity of Johannesburg", "pred_label": "__label__POS", "pred_score_pos": 0.6418254375457764} +{"content": "The VA, which provides health care for 9 million veterans, has faced challenges in managing inventory at its pharmacies. For example, VA medical centers have struggled to accurately account for and update information on medications in stock.\nIn this report, we found that VA cannot fully oversee management of pharmacy inventories system-wide because VA lacks\na comprehensive system to manage pharmacy inventory—a new system will not be implemented for up to10 years\na focal point for system-wide oversight.\nWe recommended that VA designate a focal point to oversee system-wide pharmacy inventory management.\nThis automated medication dispensing machine at a Department of Veterans Affairs medical center allows real-time tracking of inpatient medications.\nThis photo shows rows of containers going from floor to ceiling on both sides of an aisle.\nWhat GAO Found\nSelected Department of Veterans Affairs' (VA) medical centers (VAMC) use generally similar approaches for managing their pharmacy inventories. For example, all VAMCs store certain medications in secured areas. However, GAO found that VAMCs have also taken unique approaches for procuring and tracking medications, as allowed under VA policy. For example, to better address medication shortages, one VAMC pharmacy GAO visited established a shortage committee that meets on a weekly basis. Another VAMC pharmacy uses an automated dispensing machine together with compatible software that allows the pharmacy to track the location of most inpatient medications in real-time (see figure).\nAutomated Dispensing Machine at a Veterans Affairs Medical Center\nGAO also found that VA's oversight of VAMCs' pharmacy inventory management is limited as VA lacks a comprehensive inventory management system or a focal point for system-wide oversight. In May 2018, VA signed a contract for a new electronic health records system that should allow VA to monitor VAMCs' inventories; however, VA officials expect implementation of this system to take up to 10 years. Based on a review of VA policies and interviews with VA officials, GAO found that VA has not designated a focal point with defined responsibilities for system-wide oversight of VAMCs' pharmacy inventory management. This is inconsistent with federal internal control standards for monitoring and establishing structure and authority to achieve an entity's objectives. Without a focal point for system-wide oversight, VA has limited awareness of the unique approaches that VAMCs use to manage their inventories and is missing an opportunity to evaluate these approaches. Additionally, VA cannot effectively share and standardize inventory management best practices as appropriate. Having a focal point is especially important given that VAMCs have historically had challenges in managing their inventories and a comprehensive pharmacy inventory management system may not be available for the foreseeable future.\nWhy GAO Did This Study\nVA provides health care services, including pharmacy services, to approximately 9 million veterans each year. Since 2000, VAMCs have faced recurring challenges in managing their pharmacy inventories, including difficulties with accurately accounting for and updating inventory totals through their pharmacy systems.\nGAO was asked to review VA pharmacy inventory management. This report (1) describes approaches selected VAMCs use to manage their pharmacy inventories and (2) assesses the extent to which VA oversees VAMCs' efforts to manage their pharmacy inventories.\nTo conduct this work, GAO visited a non-generalizable selection of five VAMCs chosen for the complexity of services offered and variation in location. GAO also reviewed VA national policies and local polices for the selected VAMCs and interviewed VA officials at the headquarters, regional, and local levels. GAO assessed VA's oversight of pharmacy management in the context of federal internal control standards.\nRecommendations\nGAO recommends that VA designate a focal point for overseeing VAMCs' pharmacy inventory management efforts system-wide and define the focal point's responsibilities. VA concurred in principle with the recommendation.", "pred_label": "__label__POS", "pred_score_pos": 0.9191008806228638} +{"content": "Relationships is the way in which we experience and cope with life. The concept of relationship can be used in various contexts, including the context of marriage and dating relationships. It refers to any group of people who share a common experience or background, often involving family members or relatives.\nRelationship most often refers to: Personal relationships and relatives: a close, personal, or interpersonal relationship between two people. It may include close relatives such as a brother or a sister, parents, children, and sometimes even grandparents. A romantic relationship might also be included under the term. Interpersonal relationship refers to a close, personal, or interpersonal relationship between two people, often involving two or more persons. Dependence and correlation, relationships in statistics regarding two factors or sets of information.\nTo further understand the meaning of the relationship, we have to understand first what relationships are. To elaborate this concept, let us take into consideration the example of a friendship. In this case, two people share the same experience, view, interests, or values; they also have a positive relationship, at least at the start of the friendship. However, over time the friendship develops into a more romantic one. At high levels of intimacy, the level of support and dependence for the other person grows significantly and in the end it becomes a more enduring form of relationship.\nAccording to a popular definition Civil unions or marriages are “an official union governed by public law that recognizes the civil union between the partners and provides for the legal rights, benefits, and responsibilities of those relationships.” However, as stated above, the meaning of civil union varies from one person to another and even between long-term relationships. For example, in Canada, a civil union is not considered equivalent to a marriage; whereas, in the US, a civil union is considered equivalent to a divorce. Furthermore, while a civil union is recognized in many countries, not all countries recognize same-sex civil unions. This means that there can be significant relationships among civil unions without being considered as a long-term relationship or marriage.\nFinally, we come across the third aspect that refers to the sexual attraction to another person. As previously mentioned, the term does not conform to a particular definition. Thus, same-sex relationships may exist in which one party has a dominant attitude towards the same sex or the other party is not attracted towards the same sex. The expression, “non-monogamous” does not therefore mean a same-sex sexual attraction but rather a person who have a dominant or a non-dominant sexual attraction to the same sex.\nAlthough the definition of romantic relationships differs among the different people use this term, some relationships do have clear and common characteristics. These relationships are referred to by different names like enduring, committed, ongoing, committed/open, ongoing, engaged, and dating relationships. The same-sex relationship has been referred to as a sexual relationship and the non-heterosexual has also been called a non-affective relationship. The persistence of these relationships after a period of time is what prompts people to think of the terms in the way they do.", "pred_label": "__label__POS", "pred_score_pos": 0.6954814195632935} +{"content": "Despite the ongoing challenges of COVID-19, the right to a free appropriate public education (FAPE) for students with disabilities remains in place. As schools shift to more distance learning, teams of educators are left to redesign what FAPE looks like when they cannot be physically present with their students. That’s why the Center, in partnership with the Diverse Learners Cooperative, has created a guide that offers a decision-making model that aims to balance individual student needs within a virtual learning context, as well as a range of exemplars showing how this model can be applied.\nReading Time: < 1 minute", "pred_label": "__label__POS", "pred_score_pos": 1.0000035762786865} +{"content": "No matter how many times I see the fall foliage, it doesn’t cease to amaze me. I’d like to say I appreciate all things with the same awe, but it’s not the case.\nI often wonder if it is the way it looks or the way I look at it, and why do some people, places, things, and experiences become mundane and others continue to inspire us forever.\nMy hiking buddies and I often joke about how we feel bad for squirrels, who aren’t featured in many photos and do not get even a small amount of attention compared to other wildlife. At the same time, I recall when friends and relatives visited Long Island from other countries, they were in awe of these common grey fur balls.\nOur reactions are somewhat based on our perceptions and on values we assign, whether we are aware of it or not.\nRegardless of the reason, I hope the fall foliage never ceases to draw me in, and I continue to appreciate it with wonder year after year.\nPortrait of Fall By Alora M. Knight\nLooking out my window\nIn October’s golden light, I see a beauty unsurpassed, A truly lovely sight.\nLeaves are saying soft good-byes\nAs they come floating down To make a nature’s carpet Of yellow, red, and brown.\nMountain tops, now turned to white,\nForewarn of winter chills, While trees, like golden rivers, Wind their way up through the hills.\nThroughout our world’s creation\nYou will ever find it thus, Kaleidoscopes of color, In God’s hand, the artist’s brush.\nPHOTO: @be_naturae", "pred_label": "__label__POS", "pred_score_pos": 0.5008320808410645} +{"content": "Authors: Elizabeth Fitch, Alison Krentel, Kevin Bardosh, Beth Sutherland, Alyssa Jordan, and Margaret Baker\nThe World Health Organization’s 2021-2030 NTD Road Map advocates for greater domestic ownership, mainstreaming, and integration of NTD programs, which in turn requires more capacity strengthening in the short term. This guide addresses one critical gap of the availability of resources to support the use of qualitative methods to strengthen MDA through a six-step process. It aims to facilitate adaptive program learning for MDA by providing guidance on qualitative study design, implementation, analysis, and prioritization of recommendations, while also triangulating findings with existing knowledge. The main document takes the reader through the six steps and contains links to the relevant annexes for each step of the process.", "pred_label": "__label__POS", "pred_score_pos": 0.9156928062438965} +{"content": "What's better than more eco-friendly products? Fewer products produced overall! The inconvenient truth of the climate crisis might be that we need to rewire our concept of ownership in many parts of our life, including mobility. Shared mobility concepts have become increasingly common, but they still face many obstacles. How can we design for more trust and better incentivize consumers for shared mobility solutions? How can we make them economically feasible? And how can we avoid collateral negative consequences? In this panel discussion, we'll take a look at what it will take for us - as society, industry, and individuals - to truly embrace new concepts of ownership.", "pred_label": "__label__POS", "pred_score_pos": 0.7660409808158875} +{"content": "Meet two of our lovable Community Care Unit residents, Tom and Jack.\nLoved by both staff and residents, this playful duo provide residents with comfort and support as they undergo mental health treatment.\n“As a resident of the CCU I find our two cats therapeutic. I often visit them in my quiet time and find their on-going presence to be beneficial to my mental health journey.”\nIt is well documented that the presence of animals in treatment can cause feelings of calm and optimism in both adults and children.\nThe Frankston Community Care Unit is part of Peninsula Health’s Mental Health Service, offering a program that emphasises personal recovery and a collaborative approach.", "pred_label": "__label__POS", "pred_score_pos": 0.9988402724266052} +{"content": "Overview\nDr. Greger reviews the latest cutting-edge science in this 140-minute video presentation.\nUpon ordering, you will receive\ninstant delivery of multiple, easy-to-view digital video formats:\nStreaming Video\nM4A File\nM4A Zipped\nChapters 1. Best Supplements for Prostate Cancer 2. How Lead Paint Industry Got Away with It 3. Lead in Drinking Water 4. How the Leaded Gas Industry Got Away with It 5. \"Normal\" Blood Lead Levels Can Be Toxic 6. Effects of Low-Level Lead Exposure 7. How to Lower Lead Levels with Diet (Part 1) 8. How to Lower Lead Levels with Diet (Part 2) 9. Best Foods for Lead Poisoning (Part 1) 10. Best Foods for Lead Poisoning (Part 2) 11. Can Vitamin C Help with Lead Poisoning? 12. Yellow Bell Peppers for Male Infertility? 13. The Role of Burger Viruses in Cancer 14. Microbiome We Are What They Eat 15. Best Aromatherapy Herb for Alzheimer's 16. Natural Treatment for Acne 17. Controversy Over the Trans Fat Ban 18. Banning Trans Fat in Processed Foods 19. Best Food for Sexual Dysfunction 20. Food Industry Wants Public Confused 21. What Does Low WBC Count Mean? 22. What is the Ideal WBC Count? 23. Best Supplement for Fibromyalgia? 24. Fermented or Unfermented Soy Foods? 25. Soy Foods for Prostate Cancer Prevention 26. Treating Heart/Kidney Failure with Diet\nAll of these videos are available for free on NutritionFacts.org.", "pred_label": "__label__POS", "pred_score_pos": 0.5247629880905151} +{"content": "Effects of the two-component sensor-regulator pairs DctBD and NtrBC upon the expression of a dctA::phoA fusion from Rhizobium meliloti were determined under excess and limiting nitrogen concentrations in Escherichia coli. Results indicated that NtrBC affected transcription from the dctA promoter on a number of regulatory levels and under different physiological conditions in the heterologous host. However, NtrBC-dependent cross-talk was not observed in free-living R. meliloti under the conditions tested. Comparisons of the predicted amino acid sequences of DctD and NtrC from various sources indicated a specific region of the NtrC from rhizobia, which may have diverged from a consensus NtrC/DctD sequence to minimise interference between the two component systems, NtrBC and DctBD.", "pred_label": "__label__POS", "pred_score_pos": 0.7876033186912537} +{"content": "This report summarises an assessment of a range of leading metrics that can be used to credibly measure and report on performance over time and across multiple spatial scales. The research focuses on six critical sustainability issues: deforestation, biodiversity, water use, forced labour, poverty, and Greenhouse Gas emissions.\nView items\nThis webinar provided an opportunity for those working in the palm oil sector in Asia, including on the demand side, to hear about ongoing efforts in China, India, Indonesia, Malaysia and Singapore that are strengthening demand for sustainable palm oil such as youth engagement, industry platforms, and company rankings.", "pred_label": "__label__POS", "pred_score_pos": 0.9733883142471313} +{"content": "Automotive Industry Trends: Casualty risk landscape Article information and share options\nThe automotive industry is encountering extensive upheavals on multiple fronts due to fundamental disruptions in propulsion technologies and mobility concepts. Electromobility, driving automation, computerised and connected vehicles, and the sharing economy have given rise to a myriad of interconnected trends that are significantly impacting the casualty insurance risk landscape for the automotive industry.\nOur specialist teams of risk engineers partner with the Swiss Re Institute to ensure our knowledge and expertise of the automotive industry remains highly relevant and insightful for our clients and brokers. A tool for reaching this goal is our Industry Trends Report, which aims at supporting your underwriting decisions, helping you to focus on the right risks at the right time.", "pred_label": "__label__POS", "pred_score_pos": 0.9997104406356812} +{"content": "First Paragraph\nJerome Namias (1910–1997) pioneered the art and science of long-range weather forecasting. He also set off the modern era of research in climate and atmospheric science at Scripps Institution of Oceanography. Largely self-taught, Namias developed an exceptional physical intuition for the intricate interplay between atmosphere and ocean. In an era when the skill of weather forecasts was limited to two or three days, Namias advocated the heretical notion that climate, the sum total of weather, might be predictable for weeks, months, or even longer. He was among the first to realize that planetary-scale air-sea interactions strongly influence climate variability and thereby make certain, specialized types of predictions possible far beyond the time horizon of ordinary weather forecasts.", "pred_label": "__label__POS", "pred_score_pos": 0.7407686710357666} +{"content": "As we have already seen, Covid-19 is fundamentally altering what work is performed and how we perform it. With this in mind, now is the time to think about improving your selection process. That begins with the interview.\nDuring this webinar, we discuss the methods and approaches to enhancing interview effectiveness with the goal of improving selection.", "pred_label": "__label__POS", "pred_score_pos": 0.910677969455719} +{"content": "Alcoholics Anonymous\nNo matter how strong your love, if someone is not motivated to help themselves, no matter how much they beg you, you cannot do the work for them.\nI may not be popular for saying this, but guess what -- people relapse; that's a reality on the path to recovery. And if anything, over the years, I've discovered that the more people who know I'm in recovery, the more support I'm exposed to when I might be struggling and prone for a relapse.\nAddiction is misunderstood, and it leaves those suffering from the condition stigmatized. Society makes the assumption that an addict has a personal problem, not a medical one.\nIt was the great Carl Sagan who said: \"If you wish to make an apple pie from scratch, you must first invent the universe", "pred_label": "__label__POS", "pred_score_pos": 0.9948091506958008} +{"content": "For some couples, staying at home during COVID-19 has been a blessing. It has opened up opportunities to improve communication, discover new idiosyncrasies, and spend quality time pursuing mutual interests and hobbies. However, many couples have also noted that being cooped up with their partner has led to the discovery of more areas of improvement within the relationship. With the increase in contact, it is not unusual to experience more frequent arguments and difficulty cop", "pred_label": "__label__POS", "pred_score_pos": 0.9248020052909851} +{"content": "Title Date of this Version\nSpring 4-4-2011\nAbstract\nTen members of Lincoln Fire and Rescue in Lincoln, Nebraska agreed to participate in a thirteen week tactical strength and conditioning fitness program conducted by Athology Inc. that included a Physiological, Physical, and Cognitive Component. Participants completed three workouts per week lasting approximately 90 minutes each, conducted by fitness trainers from Athology Inc. Participants completed lab draws at the beginning and end of the program as well as an EKG at the onset of the program, conducted off-site at a local hospital. Participants completed performance and agility testing at the onset and end of the program. Lastly, participants completed cognitive testing at a baseline, following a workout during the first week of the program, six weeks into the program, and during the final week of the program. Medical, fitness, and agility testing assessed changes in physical performance over the thirteen weeks, and cognitive testing assessed performance on cognitive tasks related to firefighter performance following a physically strenuous task. Finally, significant variables were combined to form an aggregate fitness and experience variable to test their impact on working memory and domain-specific decision making. In conclusion, fitness and experience did not predict performance on a working memory or decision making task for professional firefighters.", "pred_label": "__label__POS", "pred_score_pos": 0.7390865683555603} +{"content": "As Western blood transfusion practices are changing, there is interest and need in anticipating the future demand of blood products and how a blood establishment can actively prepare for various long-term developments. This article provides an overview of how a scenario approach was used to prioritize key categories of drivers for the future demand of red blood cells and the organizational implications thereof for Sanquin, the Dutch national blood establishment.Study Design and Methods\nBased on previously identified drivers from interviews and a literature review (Step 1), we conducted scenario sessions and a survey to rank a list of drivers (“themes”) with its related opportunities and threats (Step 2), to identify mitigating measures per theme through focus groups (Step 3).Results\nIn Step 2, 10 themes were found that were classified in terms of importance and uncertainty. These were plotted on a two-dimensional graph with an ellipse to indicate the interquartile ranges per theme. Experts rated the top three most important themes to be the blood supply organization, precision medicine, and red blood cell replacements. In Step 3, focus groups identified specific mitigating measures per theme. These measures had parallel ideas, such as the need for an innovative mentality, internal and external communication and collaboration, and building Sanquin's reputation and trust with the public.Conclusion\nHaving identified the most important themes with suggestions for mitigating measures, Sanquin can take steps to become adaptive and proactive. Other blood establishments may also use a scenario approach to create contextualized long-term strategies.", "pred_label": "__label__POS", "pred_score_pos": 0.6286742091178894} +{"content": "Fitch Ratings has affirmed Uzbekistan’s long-term foreign-currency Issuer Default Rating (IDR) at BB- with a stable outlook.\nFitch said it was expecting the Uzbek economy to expand by 6.2% in 2021 adding that the growth would maintain strong momentum, averaging 5.7% in 2022-2023 supported by a gradual pace of fiscal consolidation, strong investment, continued access to external financing and reforms positively impacting agriculture, construction and industrial production.\nThe same forecast was earlier unveiled by the World Bank’s Autumn Europe and Central Asia Economic Update.\nFitch forecasts that Uzbekistan’s overall fiscal deficit would increase to 5.2% of GDP in 2021, slightly below the government’s 5.5% target and the BB median forecast of 5.7%.\n“Our 2021 forecast incorporates a moderate increase in the consolidated budget deficit to 3.4% of GDP, up from 2.8% in 2020, but below the government projection of 3.7%”, the agency said.\nIt also forecasts a gradual fiscal consolidation with the overall deficit reaching 4.3% of GDP in 2022 and 3.8% in 2023, as authorities continue to emphasize spending on investment, health and education.\nGovernment debt is set to rise to 42% of GDP in 2021 from 37% in 2020. Fitch projects debt to reach 44% of GDP in 2023, still below the 59% BB median forecast, but more than double its 2018 level of 20%.\nThe rating agency added that Uzbekistan’s current account deficit would remain wider than peers’ (6.5% of GDP in 2021 and average 5.7% in 2022-2023), driven by strong domestic demand, but continued external financing availability, FDI inflows and relative stability in gold prices (62% of international reserves) would prevent significant erosion of reserves.\nFitch added that it was expecting the Central Bank of Uzbekistan to maintain positive real rates, as part of its transition to inflation targeting. The inflation is projected to decline to 9.8% until the end of the year. (Uzreport/Business World Magazine)", "pred_label": "__label__POS", "pred_score_pos": 0.5286626219749451} +{"content": "As a science-based sleep resource, we accompany our readers along their journey to a better night’s sleep. By conducting extensive research, in-house product tests, and academic reviews of journals and publications, we aim to distill scientific information into clear and accessible guides, articles, and recommendations.\nPrior to publication, all content of Sleep Science undergoes a thorough writing and review process.\nWe exclusively use reputable, data-driven sources. For our articles, these include peer-reviewed medical journals, data from academic and scientific research, reports from government agencies, and recommendations from legitimate associations such as The National Sleep Foundation. For our product guides and reviews, we source from in-house product tests, verified customer experiences and direct feedback, and publicly available information from brand websites and product pages.\nAfter our writers draft their original work, our team of reputable Sleep Researchers fact-check and revise these to ensure that they are accurate and scientifically sound. Likewise, all content is regularly reviewed to ensure that every page is up-to-date and validated by the latest findings.", "pred_label": "__label__POS", "pred_score_pos": 0.9804528951644897} +{"content": "Abstract\nReproductive technologies may assist amphibian conservation breeding programs (CBPs) to achieve propagation targets and genetic management goals. However, a trial-and-error approach to protocol refinement has led to few amphibian CBPs routinely employing reproductive technologies with predictable outcomes. Additionally, while injections can be safely administered to amphibians, perceived animal welfare risks, such as injury and disease transmission, warrant the development of alternative hormone administration protocols. The present study investigated the spermiation response of roseate frogs, Geocrinia rosea, administered various doses of human chorionic gonadotropin (hCG) and gonadotropin-releasing hormone agonist (GnRH-a) via subcutaneous injection. This study also quantified the spermiation response of frogs administered both hormones via topical application. Total sperm, sperm concentration and sperm viability were assessed over a 12-h period post hormone administration. Males released sperm in response to the injection of hCG (88-100% response; 5, 10 or 20 IU), but all samples collected from males administered hCG topically (100, 100 + DMSO or 200 IU hCG) were aspermic. In contrast, males consistently released sperm in response to both the injection (100% response; 1, 5 or 10 μg), or topical application (80-100% response; 50, 50 + DMSO or 100 μg) of GnRH-a. Overall, the administration of GnRH-a was more effective at inducing spermiation than hCG. Mean total sperm and sperm concentration were highest in response to the optimal topically applied dose of 100 μg GnRH-a (mean total sperm = 2.44 × 103, sperm concentration = 1.48 × 105 sperm/ml). We provide novel evidence that topical application provides a viable alternative to injection for the administration of GnRH-a to induce spermiation in amphibians.", "pred_label": "__label__POS", "pred_score_pos": 0.699487566947937} +{"content": "Abstract\nEvaluation of the biological control program against\nDiatraea spp. (Lepidoptera: Pyralidae) on sugar cane in Trinidad. AbstractInoculative releases of the imported tachinids Lixophaga diatraeaeand Metagonistylum minensewere conducted in sugarcane plantations in Trinidad over a period of 15 years for the control of Diatraeaspp. (mainly D. saccharalis). However, permanent establishment of the parasitoids has not been recorded. The most effective tachinid has been the indigenous species Paratheresia claripalpis,with a specific parasitism rate of 5.0%, followed by L. diatraeae(0.6%) and M. minense(0.2%). Other parasitoids include Cotesia flavipes(5.0-10.0% parasitism) and Agathis stigmaterus[ Alabargus stigma] (0.5-2.0%). Allorhogas pyralophagus,introduced from Mexico, had a parasitism rate of <5.0%. Following the release of 11 parasitoid species, the overall parasitism rate was 16.3-23.5%. This resulted in a gradual reduction of damage due to Diatraeaspp. from 16.9% in 1984 to 5.7% in 1987. Computer predictions indicated a reduction in damage by Diatraeaspp. to below the accepted economic threshold of 5.0% during 1987-89.", "pred_label": "__label__POS", "pred_score_pos": 0.9979012608528137} +{"content": "Empagliflozin: effects within the heart and vessels. Finally, we focus on practical management issues regarding SGLT2i use in association with additional T2D and HFrEF common pharmacological therapies. Security considerations will also be highlighted. Considering the paradigm shift in T2D management, from a focus on glycaemic control to a broader approach on cardiovascular safety and event reduction, including the potential for wide SGLT2i implementation in HF individuals, with or without T2D, we are facing a encouraging time for major changes in the global management of cardiovascular disease. Electronic supplementary material The online version of this WF 11899A article (10.1007/s10557-020-06973-3) contains supplementary material, which is available to authorized users. value (HR 0.78, 95% WF 11899A CI 0.61C1.00,\np?=?0.05), or all-cause death ((HR 0.83, 95% CI 0.68C1.02, p?=?not available (NA)), but showed a pronounced reduction in HHF (HR 0.61, 95% CI 0.47C0.80, p?0.001). In aggregate, these findings suggest that in individuals with higher renal dysfunction, SGLT2i confer actually higher reductions in HHF, as also suggested from the meta-analysis results [27]. However, the degree of renal dysfunction or presence of founded CVD does not appear WF 11899A to fully explain the observed heterogeneity in terms of mortality amongst the three published SGLT2i CVOTs. Based on this heterogeneity, the 2019 Western Society of Cardiology (ESC) Recommendations [32] on diabetes, pre-diabetes and CVD, developed in collaboration with the Western Association for the Study of Diabetes (EASD), offers given empagliflozin a class IB recommendation to reduce the risk of death in individuals with T2D and CVD. In addition, empagliflozin, dapagliflozin and canagliflozin are recommended in individuals with T2D and CVD or at very high/high CV risk, to reduce CV events, as first-line antidiabetic therapy in naive individuals, not previously treated with metformin [32]. This recommendation is definitely criticized, namely from the convincing beneficial effects (HbA1c 6.5C7.5%) (glycated haemoglobin) of early combination therapy [33]. A CVOT with the SGLT2i ertugliflozin [26] is currently underway, with results expected in the near future (Table ?(Table11). SGLT2i Effects on HF Results in T2D Individuals Additional subanalyses of the three abovementioned CVOTs [20C22] have been published, exposing further data concerning SGLT2i effects on HF results in individuals with T2D. An analysis of the CANVAS system showed that canagliflozin reduced the overall risk of HF events in individuals with T2D and high CV risk, with no obvious difference in effects on HFrEF vs. HFpEF events [34]. A recent analysis of the DECLARE-TIMI 58 trial investigated the effectiveness of dapagliflozin in T2D individuals considering baseline HF status [25]. In individuals with T2D and baseline HFrEF, dapagliflozin reduced HHF, CV death and all-cause mortality, whereas in individuals with T2D without baseline HFrEF, the only reduction observed was in HHF [25]. SGLT2i Rabbit polyclonal to AHCYL1 HF-Dedicated Results Trials in Individuals with or without T2D More recently, the DAPA-HF trial results were published [35]. The trial included 4744 HFrEF individuals with our without T2D adopted over a median of 18.2?weeks. It was shown that dapagliflozin 10?mg daily significantly reduced the primary composite endpoint of worsening HF (including HHF or urgent HF visits) and CV death inside a population highly treated with background disease-modifying HF therapies (HR 0.74, 95% CI 0.65C0.85, p?=?0.001), either in individuals with (HR 0.75, 95% CI 0.63C0.90, p?=?NA) or without diabetes (HR 0.73, 95% CI 0.60C0.88, p?=?NA) [36]. The number of individuals needed to treat (NNT) with dapagliflozin to prevent one main event during the trial duration was 21 (95% CI 15C38). Importantly, inside a post hoc analysis including individuals on concomitant sacubitril/valsartan therapy at baseline (nearly 10% of the trial populace), the HR for the primary outcome was consistent amongst individuals on- or off-sacubitril/valsartan. Despite the low percentage of individuals treated with sacubitril/valsartan at baseline, it appears that the benefits of SGLT2i therapy are additive to the people afforded by neurohormonal modulating providers. Moreover, possible heterogeneity was observed according to New York Heart Association (NYHA) practical class, showing higher treatment benefit in class II individuals, compared with class III or IV [35]. Regarding security, the event of adverse events (AEs) was low and related between dapagliflozin and placebo, except for significantly more severe renal adverse events (AEs) in the placebo group (2.7% vs. 1.6%, p?=?0.009) [36]. Table ?Table22 and Table ?Table33 summarize the ongoing HF-dedicated outcomes [36C38] and functional capacity clinical tests with SGLT2i, that may enhance the body of evidence for these providers in HF populations. Table 2 Summary of published or ongoing dedicated heart failure end result tests of SGLT2i\nNCT quantity0305795103057977036192130303612403794518Active compound/comparatorEmpagliflozin/placeboDapagliflozin/placeboDapagliflozin/placeboPioglitazone + dapagliflozin/placeboPopulationHFpEFHFrEFHFpEF with or without T2DHFrEF with or without.", "pred_label": "__label__POS", "pred_score_pos": 0.9538522362709045} +{"content": "De Dreu and Gross's distinction between attack and defense is complicated in real-world conflicts because competing leaders construe their position as one of defense, and power imbalances place status quo challengers in a defensive position. Their account of defense as vigilant avoidance is incomplete because it avoids a reference to anger which transforms anxious avoidance into collective and unified action.", "pred_label": "__label__POS", "pred_score_pos": 0.5516961812973022} +{"content": "Delaware County, Ohio Print\nJoined the AARP Age-Friendly Network:\n2/12/2018\nLead Agency: My Source Point\nLocal non-profit\nAction Plan\nDelaware County developed its action plan using both qualitative and quantitative community data, focusing on six primary areas. The action plan commits to ensuring that older adults have more affordable, accessible, and safe housing and transportation options. The county is also working to provide safe and accessible gathering spaces for people of all ages, while ensuring that older adults have the community support, health, and safety services they require. The plan highlights that health and social services are well-distributed, conveniently located, and offer an adequate range of community supports that promote, maintain, and restore health for people of all ages and abilities. Delaware County is committed to distributing regular and reliable information to older residents through different sources, such as mail, email, newspaper, and radio, as well as through public meetings, community centers, and clubs.\nAction Plan Highlights HousingFocus on financial concerns and housing affordability for older adults by creating a directory that identifies legal and financial options related to housing, rebooting home safety checks as part of fall prevention, and working with community leaders, development and government officials to increase stock of affordable and accessible housing. TransportationHelp residents find individualized transportation solutions based on their unique circumstances through Mobility Manager consultations that support older adults in meeting their mobility needs with individualized resources. Outdoor SpacesIncrease access to outdoor spaces by creating a color-coded quadrant map of the county that includes all natural and paved trails, Preservation Parks, community municipalities, accessible restrooms, parking and other accessibility accommodations.", "pred_label": "__label__POS", "pred_score_pos": 0.6760320067405701} +{"content": "Women typically earn less yet live longer than men, which suggests they need a different financial plan. Here are 13 strategies to ensure a comfortable retirement\nOf men collecting benefits in 2008, 58% were below the full retirement age. If your husband has been the higher earner, the longer he waits to collect, the bigger your monthly benefit will be after his death.\nNEXT: Retirement: Know what's yours", "pred_label": "__label__POS", "pred_score_pos": 0.9613714814186096} +{"content": "Due to the exponentially increasing amount of data, there is a need to increase areal storage densities beyond ~1 Tb/in2. This requires the thickness of carbon overcoats (COCs) to be <2 nm. However, friction, wear, corrosion, and thermal stability are critical concerns below 2 nm, limiting current technology and restricting COC integration with heat-assisted magnetic recording technology (HAMR).\nIn a new study by the University of Cambridge, scientists used graphene for ultra-high density hard disk drives (HDD). Graphene enables a two-fold reduction in friction and provides better corrosion and wear than state-of-the-art solutions.\nScientists transferred graphene onto hard disks made of iron-platinum as the magnetic recording layer and tried Heat-Assisted Magnetic Recording (HAMR). Existing COCs don’t perform at these high temperatures, yet graphene does. Subsequently, graphene, combined with HAMR, can outflank current HDDs, giving an exceptional data density higher than ten terabytes for each square inch.\nDr. Anna Ott from the Cambridge Graphene Centre, one of the co-authors of this study, said,\n“Demonstrating that graphene can serve as a protective coating for conventional hard disk drives and that it can withstand HAMR conditions is a significant result. This will further push the development of novel high areal density hard disk drives.”\nProfessor Andrea C. Ferrari, Director of the Cambridge Graphene Centre, added:\n“This work showcases the excellent mechanical, corrosion, and wear resistance properties of graphene for ultra-high storage density magnetic media. Considering that in 2020, around 1 billion terabytes of fresh HDD storage was produced, these results indicate a route for mass application of graphene in cutting-edge technologies.”\nThe study was conducted in collaboration with teams at the University of Exeter, India, Switzerland, Singapore, and the US.\nJournal Reference: Dwivedi et al. Graphene Overcoats for Ultra-High Storage Density Magnetic Media. Nature Communications 12, 2854 (2021), DOI: 10.1038/s41467-021-22687-y", "pred_label": "__label__POS", "pred_score_pos": 0.8969639539718628} +{"content": "Impact3 understands at times of rapid Company growth, strategic alignment is essential across all facets of the organisation. Growth requires internal transformation to meet the new market paradigm. However, fractures can emerge if there is a disconnect between the internal business strategy and the external market forces, This can create downstream tension for Management, employees, customers and investment prospects.\nImpact3 collaborates with you to navigate through unchartered waters, where the needs of Management and employees change quickly. Applying our marketing process of listening internally, delving deep into markets and customer testimonies, we document key insights to objectively understand the unique issues you are facing.\nWe identify market opportunities and potential Company gaps. The output is well-documented and meaningful strategic business insights. This empowers your Management team and people to translate insight into business action. The key deliverable is a business positioning strategy, to ensure a clear vision for continued Company growth. .\nBy strengthening the Business positioning and enabling alignment your organisation will prosper. The key outcome for your organisation is that Management and your people will grow and thrive.\nDrop us a line to understand more, and discover how we can support your business journey.\nConnect to Impact3 Partnership\nIn the spirit of reconciliation, the Impact3 acknowledges the Traditional Custodians of country, throughout Australia and their connections to land, sea and community. We pay our respect to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.\nCopyright © 2020 Impact3 Partnership - All Rights\nWe use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.", "pred_label": "__label__POS", "pred_score_pos": 0.6660980582237244} +{"content": "Liberalism is egalitarian in principle, but why doesn't it do more to promote equality in practice? In this book, the distinguished political philosopher Michael Walzer offers a critique of liberal theory and demonstrates that crucial realities have been submerged in the evolution of contemporary liberal thought.\nIn the standard versions of liberal theory, autonomous individuals deliberate about what ought to be done-but in the real world, citizens also organize, mobilize, bargain, and lobby. The real world is more contentious than deliberative. Ranging over hotly contested issues including multiculturalism, pluralism, difference, civil society, and racial and gender justice, Walzer suggests ways in which liberal theory might be revised to make it more hospitable to the claims of equality.\nCombining profound learning with practical wisdom, Michael Walzer offers a provocative reappraisal of the core tenets of liberal thought.Politics and Passionwill be required reading for anyone interested in social justice-and the means by which we seek to achieve it.\neISBN: 978-0-300-12770-6\nSubjects: Political Science\nTable of Contents\nYou are viewing the table of contents\nYou do not have access to thisbookon JSTOR. Try logging in through your institution for access.", "pred_label": "__label__POS", "pred_score_pos": 0.7812298536300659} +{"content": "Yin is a practice that reminds us to slow down, and embrace stillness. In our fast paced (Yang) world, this is not always easy to prioritize—often feeling uncomfortable. Slowing down for mindful connection with ourselves is necessity to live a balanced life. Understanding the practice of Yin can truly help us restore harmony and balance within ourselves.Read now You will often see a colorful diagram showing the chakras and their rainbow-like colors. These colors are very often used during chakra meditations, visualizations, and yoga. Colors have rich, vibrant and healing energies, which affect us psychologically, emotionally and spiritually.Read now", "pred_label": "__label__POS", "pred_score_pos": 0.9262219667434692} +{"content": "This method helps to understand users emotions and thoughts behind actions they can to with the product.\nGet a deeper understanding of the systems requirements by defining use cases with actors, goals and system processes.\nA method to sort ideas or information concerning a topic.\nGuide a discussion with potential users to gather insides about their opinion on a product.\nCreating fictional personas increases empathy for the target group and can help in the design process of a product.\nThis methods aims towards prototyping in all stages of a design process. This might enhance a better understanding of the product.\nThis method helps you to get a deeper look into the target group by defining characteristics and needs.\nThis complex method reveals opportunities for addressing the pain points of customers, alleviating fragmentation and ultimately creating a better experience for your users.\nThis qualitative interview brings findings about the system-to-be's surrounding. Interviewees are potential users. Some skills about interviews are relevant.\nThis method is really helpul subsequently to a brainstorming-type-of-method. After gathering lots of ideas some clustering is needed!", "pred_label": "__label__POS", "pred_score_pos": 0.826324462890625} +{"content": "Key takeaways:\nFashion brands struggle to both measure their own sustainability efforts and communicate their progress to customers.\nMany organisations act both as industry guides and watchdogs, setting guidelines for improvement while also raising questions about trust.\nDespite intentions, these initiatives are often constrained by factors like other industry forces and brands’ own limitations.\nIn the six years leading up to the Rana Plaza disaster in 2013, hundreds of garment workers died in several smaller factory disasters. In most, if not all cases, auditors had inspected the factories, but overlooked clear hazards like structural building flaws and lack of fire escape routes. Factories in Rana Plaza itself had been inspected and deemed in compliance with the monitoring group’s code of conduct.", "pred_label": "__label__POS", "pred_score_pos": 0.9944478869438171} +{"content": "Despite higher inflation, labour shortages, and wage inflation, corporate confidence is growing across the world. There is a consensus that, despite the lingering impact of the pandemic, we are through the worst of times. Consumer confidence is also high and rising, starting with China and the West and gradually spreading to other economies.", "pred_label": "__label__POS", "pred_score_pos": 0.9995269775390625} +{"content": "Sewage sludge is one of the sinks for PAHs accumulation and concerns are growing regarding the environmental risk of the discharge of PAHs in waste activated sludge (WAS) as a major byproduct of sewage treatment. Here, we evaluated the effectiveness of ozone treatment to eliminate the 16 priority PAHs in WAS. The PAHs removal efficiency increased with ozone dosage and was strongly pH dependent. Even at ozone dosage of 40 mg O3·g-1, the PAHs removal efficiency at pH 9.0 (44.5%) was significantly higher than that observed at pH 5.0 and 200 mg O3·g-1 (41.7%). The pH-dependent elimination behavior of PAHs was attributed to the varying yield of hydroxyl radicals (OH) and degree of sludge disintegration (R2 = 0.88-0.92). Over 96% of the PAHs were in the particulate flocs (PF) phase, while the fraction bound to the freely dissolved (FS) and dissolved and colloidal (DC) matters was negligible, indicating the need of WAS disintegration during ozonation to make PAHs more accessible to O3 molecules and OH to initiate oxidation reactions. Failure of the three-compartment model to describe the PAHs sorption behavior in sludge matrix during ozonation implied that oxidation reaction occurred simultaneously with the partitioning of PAHs from PS to DC/FS fraction. Lastly, the results of the intermittent ozonation experiment demonstrated the interference of soluble organic compounds during PAHs degradation, particularly proteins and humic substances, as O3 and OH scavengers. At ozone dosage of 120 mg O3·g-1 (pH 9.0), the PAHs removal efficiency was improved by 19.5% by intermittent ozonation, as compared to continuous ozonation under the same conditions. Copyright © 2021 Elsevier Inc. All rights reserved.\nWenhao Li, Nanwen Zhu, Yanwen Shen, Haiping Yuan.Towards efficient elimination of polycyclic aromatic hydrocarbons (PAHs) from waste activated sludge by ozonation.\nEnvironmental research.2021 Apr;195:110783\nPMID:\n33497683", "pred_label": "__label__POS", "pred_score_pos": 0.7149941325187683} +{"content": "Political Economies and Environmental Futures for the Sharing Economy Summary\nThe sudden rise of the sharing economy has sparked an intense public debate about its definition, its effects and its future regulation. Here, I attempt to provide analytical guidance by defining the sharing economy as the practice that consumers grant each other temporary access to their under-utilized physical assets. Using this definition, the rise of the sharing economy can be understood as occurring at the intersection of three salient economic trends: peer-topeer exchange, access over ownership and circular business models. I shortly discuss some of the environmental impacts of online sharing platforms and then articulate three possible futures of the sharing economy: a capitalist future cumulating in monopolistic super-platforms allowing for seamless services, a state-led future that shifts taxation from labour to capital and redistributes the gains of sharing from winners to losers, and a citizen-led future based on cooperatively owned platforms under democratic control. The nature and size of the social and environmental impacts are expected to differ greatly in each of the three scenarios. This article is part of the themed issue ‘Material demand reduction’\nKeywords: sharing economy, circular economy, access economy, peer-to-peer markets, sustainable consumption, collaborative consumption", "pred_label": "__label__POS", "pred_score_pos": 0.9961134195327759} +{"content": "A recent study examined the changes in lung function in adults with cystic fibrosis using a test called FOT, and determined its efficacy in detecting changes in the respiratory system.\nThe team observed, in agreement with previous studies, that adult Cystic Fibrosis patients are prone to obstructive airway disease. Specifically, Cystic Fibrosis patients exhibited a significant increase in RV (residual volume) and the RV/TLC ratio (residual volume per total lung capacity), when compared to controls. As a result, adults with Cystic Fibrosis have increased respiratory resistance, i.e., higher resistance from the respiratory tract to airflow during inspiration and expiration, accompanied by a decrease in the homogeneity of ventilation throughout the lungs and lung compliance (the ability for lungs to stretch and expand).\nThe authors highlight that these alterations were successfully detected by combining the FOT with the eRIC model. Therefore, FOT, the team suggests, is a new complementary approach to measure and follow pulmonary function in adult patients with Cystic Fibrosis.", "pred_label": "__label__POS", "pred_score_pos": 0.9990050196647644} +{"content": "While the COVID-19 pandemic has led to some older workers taking early retirement, many others remain on the job. They have a living to make, a family that depends on them and bills to pay. However, certain companies do not value experienced and older workers, mistreating them and, occasionally, kicking them to the curb.\nAge discrimination rears its ugly head from time to time in work environments, and employees who are victims should do their best to expose their employer. How does age discrimination emerge in the workplace? Some ways include being passed over for a promotion, and a demotion or termination to clear the way for younger, lower-paid employees.\nFederal law protects workers\nIn 2020, U.S. workers filed nearly 14,200 claims of age discrimination with the U.S. Equal Employment Opportunity Commission (EEOC). It marked the fifth year in a row that such claims had declined. Statistics dating back to 1997 showed that age discrimination claims with the EEOC peaked in 2008 with nearly 24,600 filings.\nDespite the challenges in fighting age discrimination, workers should know that federal law is on their side. The Age Discrimination in Employment Act of 1967 protects workers who are 40 years of age and older from being ousted or demoted due to age. The law makes it illegal for employers to discriminate in work matters such as hiring, training, assignments, promotions, pay and benefits. However, loopholes have limited the law, which also lost some of its bite due to U.S. Supreme Court rulings through the years.\nDifficult to prove\nAge discrimination is difficult to prove. Employers do their best to conceal any defining moments that would show the company made blatant and hostile decisions in getting rid of older workers. Instead, employers claim reasons such as reorganization and cost-cutting in making their decisions.\nIn reality, these companies target workers who are 50 and older – the ones who often make the most money and have the best benefit plans. While employees of any gender face age discrimination on the job, women are confronted with this issue most often.\nIf you are the victim of age discrimination related to your employment, understand that federal law is on your side. Your legal battle will lay the path for others in a similar position.", "pred_label": "__label__POS", "pred_score_pos": 0.6973798274993896} +{"content": "Levocetirizine is an antihistamine used to reduce allergy symptoms brought about by histamine, a natural body chemical. Levocetirizine blocks histamine’s effects, thus lowering allergic symptoms such as runny nose, watery eyes, itching eyes and nose, and sneezing.\nLevocetirizine does not prevent or treat hives or severe allergic reactions like anaphylaxis.\nOne can use this medication for other purposes that this guide does not mention. Nevertheless, always take levocetirizine as directed.\nLevocetirizine should be stopped if these symptoms are noticed:\nIn case of these severe side effects, immediately call your doctor:\nSeek emergency medical help if you have allergic reactions or side effects to the medicine. Contact Yashoda Hospitals for medical help and expert advice if you face unusual problems while taking levocetirizine.\n1. Is levocetirizine a steroid?\nLevocetirizine is an antihistamine medication used to lower symptoms like skin rashes and other allergic reactions occurring in the body due to hay fever, seasonal allergies, etc. The white blood cells produce histamine to defend against an allergen. These cause the said inconvenient allergic reactions. Levocetirizine blocks histamine, and gradually lessens the allergic symptoms.\n2. Does levocetirizine make you sleepy?\nMost antihistamine medications are well recognized to induce sleep, decrease alertness, impair consciousness, and weaken cognitive function with clinical use. Levocetirizine is a new generation antihistamine and improves these events as it does not permeate the blood-brain barrier as much as other antihistamines. It does not induce these side effects for the same reason.\n3. Is Levocetirizine safe during pregnancy?\nLevocetirizine should not be used during pregnancy if not needed. This medication comes under the US FDA pregnancy category: B. No scientific evidence has confirmed that levocetirizine causes fetal disturbance or malformation, or halts the pregnancy. Several animal reproduction studies failed to prove if levocetirizine poses a risk to the fetus.\n4. Is Levocetirizine an antibiotic?\nNo. Levocetirizine has no antibacterial properties. It is simply an antihistamine medication that blocks the production of histamine, a natural chemical in the body. It can treat symptoms of only allergic conditions like itching, rashes, runny nose, and watery eyes. It cannot resist bacterial infection, and thus is not an antibiotic.\n5. How long does levocetirizine stay in your system?\nThe onset of action of levocetirizine lasts for 28 hours. However, it takes 50 hours to be eliminated from your system. You should avoid taking levocetirizine if you are suffering from kidney disease or are undergoing dialysis. Once your symptoms disappear, you should discontinue the medication and watch the weight change.\n6. How long does levocetirizine take to work?\nThe effects of levocetirizine begin after approximately one hour. They reach their peak six hours after administration and remain for 28 hours. In the treatment of allergic rhinitis, the onset of levocetirizine's action remains for one day after taking it.\n7. Why take levocetirizine at night?\nLevocetirizine is often consumed in the morning. You can take it whenever it is suitable, either before or after a meal. However, adequate sleep is needed afterward, as levocetirizine may make you drowsy. It is recommended to avoid activities that require concentration after taking levocetirizine, like driving. Hence, it is best to take levocetirizine at night.\n8. Can I take levocetirizine twice a day?\nNot entirely. Adults and children over 12 years can take levocetirizine 5mg tablets once a day in the evening. In some cases, a 2.5 mg dose (half tablet) is given to patients once again in the evening. Do not exceed the dose of Levocetirizine. Discontinue the tablet if any side effects occur and after the symptoms have disappeared.\n9. Is Levocetirizine safe during breastfeeding?\nSmall doses of levocetirizine are normally acceptable during breastfeeding. However, if the mother exceeds the dosage, it may lead to prolonged effects and drowsiness in infants. Increased dosages can reduce milk supply, especially if consumed with a sympathomimetic drug such as pseudoephedrine.\n10. Does Levocetirizine cause weight gain?\nLevocetirizine blocks histamine to relieve allergic symptoms. This medication has been established to increase appetite in many cases and cause potential weight gain. Post the relief of the symptoms, you should discontinue the medication and watch the weight change.\nFor more detailed information regarding this medication and qualified medical advice, consult our healthcare experts at Yashoda Hospitals.\nNecessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.\nCookie Duration Description cookielawinfo-checkbox-analytics 11 months This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category \"Analytics\". cookielawinfo-checkbox-functional 11 months The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category \"Functional\". cookielawinfo-checkbox-necessary 11 months This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category \"Necessary\". cookielawinfo-checkbox-others 11 months This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category \"Other. cookielawinfo-checkbox-performance 11 months This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category \"Performance\". viewed_cookie_policy 11 months The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.\nFunctional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.\nPerformance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.\nAnalytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.\nAdvertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads.\nOther uncategorized cookies are those that are being analyzed and have not been classified into a category as yet.", "pred_label": "__label__POS", "pred_score_pos": 0.5211043357849121} +{"content": "This guide explains prescription drug monitoring programs (PDMPs), and how they can enhance clinical decision making. The guide also explains how PDMP improves patient safety, while helping to decrease prescription drug misuse and unintentional overdose deaths.\nThis manual offers guidance on how to engage youth during government-sponsored events and meetings. It includes resources to support youth services, youth development, youth leadership, civic engagement, and youth organizing.\nThis guide offers strategies for communities on collaborating with faith-based organizations to address the service needs of people living with mental illness, substance use disorders, or both. It highlights examples, and presents challenges and benefits.\nThis manual offers mental health professionals models and techniques for working with people living with co-occurring disorders. It describes screening and assessment and lists five guiding principles for effective management.", "pred_label": "__label__POS", "pred_score_pos": 1.0000096559524536} +{"content": "President of the General Assembly : Devajna Karan Gopal\nDear delegates and MUN directors,\nAs the advent of the World Wars in the 20th century brought upon years of tempestuous disillusionment, the world witnessed a dramatic rise in the number of Westphalian sovereign polities. This renewed world order inaugurated great expectations: accountable governance was on the horizon, and hurdles to socio-economic development were soon to be overcome. For several states, sovereignty has delivered on these expectations and ushered in an era of better living standards and contentment. However, between the life expectancies of Singapore and Liberia is an alarming gap, a gap that illustrates the dismal failure of sovereignty in less fortunate polities.\nIn these 'failed' states, human rights violations, crime, corruption, and other impediments to development erode the government's legitimacy. Social unrests and conflicts continue to ravage the nations and aggravate internal strife. Nevertheless, large revenue streams from the sale of natural resources and foreign aid along with the proscription of foreign annexation of territories post-WWII, have reduced incentives for corrupt members of these governments to consider and make prudent policy changes.\nWhile the consequences of ineffective governance are grave for most citizens in these countries, cross-border threats that emerge from these conditions, such as terrorism, have provided significant incentives for the leaders in the world's most powerful and successful polities to aid the development of capable governing systems. The deployment of American troops in Iraq and Afghanistan is perhaps the most well-known example of a foreign power allocating significant funds and resources to set up a new governing structure in a poorly governed nation. With the withdrawal of the troops this year marking the recognition of the American government's failure to promote better governance in these countries, another policy option seems to be a promising alternative: Shared Sovereignty.\nAs voluntary agreements between recognized governing bodies in failed states and an external actor, shared sovereignty holds the potential to target specific failures of institutions with the cooperation of local bodies and the resources of an external actor. A clear example of such an agreement was between West Germany and the western allies during the cold war. While it operated as an autonomous state for the most part, its security policies were under the exclusive control of the allied powers. The agreement was mutually beneficial for both parties: the allies could cease the production of weapons of mass destruction in the area, and West Germany could sustain a democracy with a stable military. Furthermore, the Germans enjoyed the added benefits of being part of a market economy system, which had proven to be more successful in the West than the Soviet bloc's planned economies.\nIn recent years, the United Nations has also engaged in such arrangements with countries like Sierra Leone - establishing a Special Court to prosecute war crimes and other crimes against humanity. The court consisted of a few officials, prosecutors and judges designated by the UN Secretary-General to ensure fair trials and establish greater legitimacy to the court's verdicts. By strengthening the local judicial system in Sierra Leone and furthering the UN's progress towards SDG 16, the agreement was, again, mutually beneficial.\nSimilarly, the UN has endorsed and initiated several shared sovereignty agreements to increase equity between the world's polities in recent decades. Unfortunately, leaders often refuse to engage in shared jurisdiction accords that may significantly reduce their control over the local populace, even in failing polities. Thus, while such agreements can be effective, it is important to be practical and consider the fact that they can only exist to fulfil or control fractional aspects of a government's responsibilities. While the provision of incentives by external actors (like the aid provided to Sierra Leone for showing commitment to prosecuting criminal activity) could encourage more significant shared sovereignty agreements, several limitations exist. Would the need for external actors to provide incentives disincentivize potential efforts? Do mutually beneficial endeavours have to benefit both parties equally? Are large incentives feasible in the long term?\nDelegates at DAIMUN 2021 will engage in intense deliberation and debate on issues that highlight the political manifestations of these questions. They will analyze the limitations of shared sovereignty and evaluate its efficacy as a prominent policy option in the 21st century.\nThe Westphalian world order is collapsing.\nA new political era is approaching. DAIMUN 2021 is calling.\nYours sincerely\nDevajna Karan Gopal President of the General Assembly DAIMUN 2021", "pred_label": "__label__POS", "pred_score_pos": 0.9497026205062866} +{"content": "Supplementary Material for: Kinetics of Hepatic Volume Evolution and Architectural Changes after Major Resection in a Porcine Model\ndatasetposted on 13.02.2019, 13:17 by Bekheit M., Bucur P.O., Audebert C., Miquelestorena-Standley E., Vignon-Clementel I., Vibert E.\nThe hepatic volume gain following resection is essential for clinical recovery. Previous studies have focused on cellular regeneration. This study aims to explore the rate of hepatic regeneration of the porcine liver following major resection, highlighting estimates of the early microarchitectural changes that occur during the cellular regeneration. Background: Nineteen large white pigs had 75% resection with serial measurements of the hepatic volume, density, blood flow, and architectural changes. Methods: The growth rate initially was 45% per day, then rapidly decreased and was accompanied by a similar pattern of hepatic fat deposition. The architectural changes showed a significant increase in the Ki67 expression ( Results: p< 0.0001) in the days following resection with a peak on the 2nd day and nearly normalized on day 7. The expression of CD31 increased significantly on the 2nd and 3rd days compared to the pre-resection samples ( p= 0.03). Hepatic artery flow per liver volume remained at baseline ranges during regeneration. Portal flow per liver volume increased after liver resection ( p< 0.001), was still elevated on the 1st postoperative day, then decreased. Correlations were significantly negative between the hepatic volume increase on day 3 and the hepatic oxygen consumption and the net lactate production at the end of the procedure ( r= –0.82, p= 0.01, and r= –0.70, p= 0.03). The volume increase in the first days – a fast process – is not explained by cellular proliferation alone. The liver/body weight ratio is back to 50% of the preoperative value after 3 days to close to 100% volume regain on days 10–15. Conclusion:", "pred_label": "__label__POS", "pred_score_pos": 0.8165100812911987} +{"content": "Both public and private infrastructure actors recognize the importance of infrastructure governance to achieve strategic and sustainable outcomes and to engage all stakeholders in infrastructure planning, investment, and delivery.The final session will summarise the main takeaways from the day, highlight major lessons learned, signal opportunities and present future initiatives by the OECD and partners to ensure infrastructure governance benefits all and contributes to inclusive growth.", "pred_label": "__label__POS", "pred_score_pos": 0.987720251083374} +{"content": "Day Traders` Performance Persistence and Market Efficiency Kyung Suh Park, Young Hyun Cho 데이트레이더의 성과지속성과 시장효율성 박경서, 조영현 Abstract We propose an empirical test of weak-form market efficiency through investigating persistence in individual day traders` performance. Individual day traders buy and sell stocks repetitively within the same trading day, and have a propensity to minimize inventory of the stocks by the end of each trading days. These characteristics support the view that individual day traders base their trading decisions on technical analysis which uses past market data such as stock prices and trading volumes. According to the weak-form efficient market hypothesis, no investor can persistently achieve superior performance by trading based on historical market data. Therefore, we can reject the weak-form market efficiency if there exist some individual day traders who persistently achieve superior performance and if the proportion of superior performers exceeds some cutoff level. We use a simple performance distribution to address the statistical measure of persistent performance and the ratio of persistent superior investors, to test the efficient market hypothesis. We find strong evidence of weak-form market inefficiency. The ratio of day traders achieving persistent performance is exceedingly high, which cannot be expected to be observed in an efficient stock market. Key Words: 데이트레이더,성과분포,성과지속성,이상현상,효율적시장가설,Anomaly,Day Trader,Distribution of Performance,Efficient Market Hypothesis,Performance Persistence", "pred_label": "__label__POS", "pred_score_pos": 0.6666508913040161} +{"content": "This exhibition presents a collection called Beyond Local. It consists of everyday objects for the home that have been created in cooperation with local manufacturers. These manufacturers are all listed on the Skåne local production platform SPOK (Samtida produktion och konsumtion). The objects are what is called “backward designed”. Unlike normal practice, in which an object is designed and then taken as a blueprint to the manufacturer, the design process behind these objects began at the manufacturers.\nUsing visits and discussions to explore which processes and materials the manufacturers work with, Anna has designed these products based on what they know and do best. By investigating the manufacturers’ knowledge and skills it is possible to utilise the manufacturing process to produce more efficiently. The goal is to explore whether the potential exists to product sustainable products on a small scale and with high quality. Small scale but also industrial.\nThe Beyond Local collection consists of seemingly everyday objects, and is an example of what people often automatically buy as disposable items. This is also a product category that designers often overlook. Anna’s collection is not designed solely for function but also for decoration. Unlike their mass-produced counterparts, these objects, which are intended for small-scale production, have both character and provenance.\nThe collection is a master’s degree project by Anna Gudmundsdottir, a graduate of the five-year Master’s Programme in Industrial Design at Lund University. The work as a whole is based on SPOK, which was initiated by designer Jenny Nordberg, who was also a mentor and supervisor for the work. The project takes as a starting point the insights that have been acquired during the time SPOK has been operating. It is part of the ongoing development work that aims to explore how designers can work with local and small-scale manufacturing to foster more sustainable production.\nParticipating manufacturers: Helsingborgs Gummifabrik, ML Borstteknik, Pressmekano, Stålmannen, Herman Andersons plåt, R1 svarvare, AC snickeri", "pred_label": "__label__POS", "pred_score_pos": 0.944923996925354} +{"content": "Since the first exoplanet was discovered in 1992, scientists have identified more than 4,000 of these astronomical bodies. Exoplanets—planets found outside our solar system—have been shown to challenge traditional theories of planet formation, which were based on Earth’s own system. A recent study has revealed that gas giants can form[Read More…]\nTag: exoplanets\nEarth-like planets beyond this solar system, also known as exoplanets, are a popular target of research in the search for extraterrestrial life forms. However, the evolutionary processes that give rise to life depend heavily on the physical and chemical characteristics of habitable environments. The role of climate in shaping the[Read More…]\nScientists believe that planets outside of the solar system capable of supporting life should look a lot like Earth. The theory posits that if the chemical components comprising Earth’s atmosphere can be found in that of distant planets, those worlds could harbour similar carbon-based life-forms. This summer, two McGill University[Read More…]", "pred_label": "__label__POS", "pred_score_pos": 0.8878135681152344} +{"content": "Yesterday, our naval officers, engineers, and military experts graduated from the 51st Command and Staff Course (CSC), and the 14th & 15th CSC (Executive) courses. The graduation ceremony was held at the Goh Keng Swee Command and Staff College in SAFTI Military Institute.\n2020 has not been an easy year. Despite the challenges thrown in their way, our naval officers and engineers remained undeterred. They continued on with their respective courses to hone their leadership skills, sharpen their strategic and organisational thinking, and fine-tune their operational planning.\n\"Our journey in adapting to the COVID-19 situation was truly memorable.\" – MAJ Koh Mao Jiang, Top Navy Graduate from the 51st CSC.\n\"I remember our initial concerns at the start and questioned the effectiveness of conducting the course online. However, we soon realised that there was no other alternative – we had to adapt or risk cancelling the course. We were determined to make it work and sought to maximise every opportunity that came our way. We turned the 'negatives' into 'positives', and demonstrated adaptability and resilience which are essential qualities for the SAF to thrive in an increasingly uncertain and complex environment.\"\nAttending the CSC is not just another course to gain professional knowledge. It is also part of their SAF journey to hone their leadership acumen.\n\"Attending CSC has allowed me to gain better clarity of who I am and what I stand for. I hope that this will enable me to be a better leader, one that will guide and groom the future generations in our organisation.\" – ME5 Looi Wei Chang, Distinguished Navy Graduate from the 51st CSC.\nEchoing ME5 Looi's reflections, MAJ Li Mei Fang from the 14th CSC(E) also shared her takeaway from the course.\n\"I am more acutely aware of my individual leadership effectiveness, style, impact, and influence. While the theoretical concepts were useful, it was the practical sessions when we practiced personal coaching and \"360 feedback\" that really enhanced our self-awareness.\" – MAJ Li\n\"CSC is a pinnacle course for SAF leaders. The programme in itself is already rigorous, but it was my classmates' contributions, different perspectives, and frank conversations that elevated our learning.\"\n\"This is a life-changing course. The knowledge that I gained in this course will definitely stay with me for a lifetime. In fact, it is because of this course that I am more diligent in journaling – it's a good habit that will also help me improve my writing!\" – ME5 Ng Cheng Boon, 15th CSC(E).\nBravo Zulu to all of our navy graduates from the 51st CSC, 14th CSC(E), and 15th CSC(E)! We wish each and every one of you the very best as you continue in your journey in the navy – and we look forward to seeing you achieve great things!\n(Photos courtesy of Arron Koh and Joel Lai from NIC)", "pred_label": "__label__POS", "pred_score_pos": 0.902858555316925} +{"content": "The report identified the increasing need for ecologically friendly, reliable and secure power systems as key drivers of innovation in the sector.\nAn analysis of\nABB, Eaton, HP and other top suppliers' strategies are included in the study that examined market trends per subsector and geographical region from various end-user fields, including banking, healthcare, energy, government and information technology.", "pred_label": "__label__POS", "pred_score_pos": 0.9993451237678528} +{"content": "74,99 € Publisher Description\nMeeting the targets of the UN Sustainable Development Goals (SDGs) requires contributions by scientists focusing on understanding, monitoring, protecting, managing and restoring the natural environment, including geoscientists. This book presents the first detailed discussion on the role of the geological sciences (geosciences) community in the implementation of the SDGs. Unlike traditional geosciences textbooks, it is structured according to development priorities, framed in the context of the 17 SDGs. Written by international experts from diverse range of geosciences / development disciplines, it explores themes linked to both science and the professional practice of science (e.g., ethics, equity, conduct, and partnerships). The book is intended for graduate and senior undergraduate students in the earth sciences, as well as practicing geologists and experts from other sectors involved in sustainability initiatives.", "pred_label": "__label__POS", "pred_score_pos": 0.9949860572814941} +{"content": "Uganda's laws provide for select business rescue mechanisms and liquidation proceedings under both the Companies Act, 2012 and the Insolvency Act, 2011. Investors faced with financial distress can pursue formal insolvency proceedings, winding up or liquidating the business, or pursue an out-of-court settlement. Investors can also elect to pursue mediation and arbitration instead of protracted court proceedings that can be costly and take years to be resolved. Investors are at liberty to tailor their distress response to the prevailing circumstances. Startups are encouraged to elicit expert assistance to prepare a risk management plan to mitigate and enhance both foreseen and unforeseen threats (negative risk) and opportunities (positive risk) that may impact the company's solvency. Founders should be aware of the market reputation risks associated with insolvency proceedings and should act accordingly to consider less risky options, e.g., in the case of debt distress, negotiating and implementing a reorganization plan.", "pred_label": "__label__POS", "pred_score_pos": 0.6565751433372498} +{"content": "'Radical Sustainability: Exploring the need for visualisation methods in geography to aid Innovation in Greening Urban Environments' by Adelina Court\nThe green agenda is high on the national government agenda, with a new £40 million scheme to encourage a sustainable recovery alongside policies, such as the 25 Year Environment Plan and other tools, pushing more investment into the area. With this push, we are now seeing innovation in urban green infrastructure: from pocket parks to the Americanised models of community gardens, becoming more frequent across our cityscapes. This paper critically explores the rise of ‘radical sustainability’ and the need to embrace new forms of urban green infrastructure. We present a case study of a multifunctional forest school in Salford, reflecting on our work in enabling the project, along with its potential impacts. The multidisciplinary team made up of an urban geography, a contextual studies scholar, and an illustrator, also present a visual methodology framework which could be replicated in future studies. The paper demonstrates the transformative nature of radical schemes and calls for more funding to push forward the practice in the North West and beyond.", "pred_label": "__label__POS", "pred_score_pos": 0.890723705291748} +{"content": "抄録\nThe roles of astrocytes in the CNS have been expanding beyond the long held view of providing passive, supportive functions. Recent evidence has identified roles in neuronal development, extracellular matrix maintenance, and response to inflammatory challenges. Therefore, insights into astrocyte secretion are critically important for understanding physiological responses and pathological mechanisms in CNS diseases. Primary astrocyte cultures were treated with inflammatory cytokines for either a short (1 day) or sustained (7 days) exposure. Increased interleukin-6 secretion, nitric oxide production, cyclooxygenase-2 activation, and nerve growth factor (NGF) secretion confirmed the astrocytic response to cytokine treatment. MS/MS analysis, computational prediction algorithms, and functional classification were used to compare the astrocyte protein secretome from control and cytokine-exposed cultures. In total, 169 secreted proteins were identified, including both classically and nonconventionally secreted proteins that comprised components of the extracellular matrix and enzymes involved in processing of glycoproteins and glycosaminoglycans. Twelve proteins were detected exclusively in the secretome from cytokine-treated astrocytes, including matrix metalloproteinase-3 (MMP-3) and members of the chemokine ligand family. This compilation of secreted proteins provides a framework for identifying factors that influence the biochemical environment of the nervous system, regulate development, construct extracellular matrices, and coordinate the nervous system response to inflammation.\nASJC Scopus subject areas 生化学 分子生物学", "pred_label": "__label__POS", "pred_score_pos": 0.8522514700889587} +{"content": "If you're in the hauling business, your livelihood can depend on the condition of your truck tarp. Truck tarps from D.S. Sewing — made of the highest quality vinyl-coated polyester — can last up to three years with proper care. Fortunately, proper care doesn't involve anything complicated. There are just a few simple steps you must take to protect your investment from the worst enemy of tarp fabric: abrasion. \"Since the tarp is a tool that you have to use everyday, it's best to take care of it,\" says D.S. Sewing President Dave Steinhardt.\nTo illustrate how destructive abrasion can be to a truck tarp, Steinhardt likens highway driving to a hurricane. Winds in a hurricane can reach 60 mph and higher — just like your flatbed truck on an Interstate.Even when there is no wind, your entire truck is shaking and rattling all day long as it barrels down the freeway. Under those conditions, objects as small as splinters or burrs can rub against your truck tarp and wear through even the best fabric.\nIf a hole develops, you've got a problem. How are you going to keep rain and salt off a load of lumber? Or paper bags filled with concrete mix? Or skids of nails in cardboard boxes? Here's one suggestion for keeping your tarp in tip-top shape: after your flatbed is loaded with cargo, take a walk around the truck. Look for points sticking out — even small ones, that might rub against the tarp. It is often easy to smooth over these areas if they are noticed in time. For example, metal crimps on bundles of lumber could wreak havoc on a tarp. Use duct tape to cover the crimps, or pound them down with a hammer.\nHarmful abrasion can even result from improper installation of the \"s\" hooks securing a tarp to your truck. Steinhardt once sold a tarp to a truck driver who fastened the hooks with the bottoms facing inward. When Steinhardt noticed the mistake, he had to remove and re-attach every hook — with the bottoms facing outward. If the hooks had remained the way the driver installed them, the sharp edges could have cut right through the tarp in dozens of places.\nFinally, remember that abrasion can work against your tarp even when you're not carrying any cargo. A folded-up tarp sitting directly on your empty flatbed will rub against rocks and other tiny particles at 60 mph until they become lodged in the fabric. To avoid having your tarp resemble a giant piece of sandpaper, place a carpet or piece of cardboard underneath before strapping it to your empty flatbed. Drivers have also been known to place their idle tarps on the deck plates behind their truck cabs. But these areas have rough surfaces to avoid slippage, so use carpet or cardboard there as well. These simple steps will ensure you get the longest possible life out of your D.S. Sewing tarp. \"We're saying, 'Take care of your tarp,'\" Steinhard says. \"Remember, you're in a hurricane all day long.\"", "pred_label": "__label__POS", "pred_score_pos": 0.6148207783699036} +{"content": "Does rap music promote violence?\n210803 | by: Nikki Garcia\nDoes rap music actually promote violence?\nOn my Instagram story, I conducted a poll with a simple question:\nDoes rap music promote violence? Then, I added a box that asked for the user's reasoning. Of course, the votes were divided, with some being reasonable and others being unreasonable.\nAs you can see, 91 percent of those who voted stated that rap music does not inspire violence, while 9 percent thought it did (out of 47 users). Unfortunately, none of the people who voted yes provided a rationale for their decision. Here are a few compelling arguments for why users feel rap does not promote violence:\nMusic at the end of the day are just words. Violence is caused by the person’s doing. -Anonymous There are a lot of artists who rap about topics other than violence/decry violence outright. -Anonymous Not all rap music but some definitely [do], but all music genres can do that though. -Anonymous It depends on the artist, artists like NBA YoungBoy, Chief Keef, Playboi Carti usually do. On the other hand, artist[s] like 2Pac, Mozzy, and Biggie speak about their life experiences. So it truly depends on the artist and what type of art they like to produce. -Anonymous However, according to a study done by Western Connecticut State University, this is not the case. Young individuals who listen to rap music are more likely to engage in violent behavior, according to a study performed by Western Connecticut State University. Eleven people viewed a violent music video, eleven people saw a nonviolent music video, and eleven people didn't watch any music videos at all, serving as the control group. The findings of this experiment were noteworthy, revealing that the furious tone of the music videos displayed, along with the obscene lyrics and exhibition of weaponry, elicited animosity in the study's participants. The Chicago Tribune, on the other hand, presented a compelling case. They claimed that the vast majority of rappers that use violence and obscenity in their songs have experienced the things they rap about and are only expressing their reality. Those listening to the music may be able to relate to it based on their own experiences, causing them to feel more connected and appear more affected.\nIn this case, I agree with The Chicago Tribune because, as many others in my survey indicated, rap raises consciousness and experiences while not totally encouraging violence. Logically, violence can only be created by someone who decides to do so. As a result, I agree with the assertion that rap does not precisely promote violence. After all, it's simply music at the end of the day.\nWriter’s Note: Thank you to everyone who took the time to reply to the poll; I appreciate it!", "pred_label": "__label__POS", "pred_score_pos": 0.7981196641921997} +{"content": "A group of prominent Senators has urged the Joe Biden Government to accelerate visas for international students. If implemented, this decision will benefit innumerable Indian students anxiously waiting to attend classes from the Fall. For example, just emergency visas are being issued at present in Delhi at the U.S. Embassy. As a result, a sizable number of students remain anxious about their academic prospects for the next session starting from this Fall. The Senator group has stated that there are 100,000+ Indian students in the United States, contributing sizably towards the economy.\nRead More: Cost of Studying in USA\nThe letter from the group to Secretary of State, Tony Blinken, stated concerns relating to the slow processing of student visas with the country continuing to heal from the coronavirus pandemic. The State Department has been requested to offer consistent and reliable consular solutions while ensuring maximization of alternatives for in-person interviews for visas through virtual interviews and waivers, authorization of overtime for staff members, increasing hiring, extension of visa eligibility based waivers and initiation of better engagement with external agencies and all stakeholders.\nThe letter highlights the vital juncture in the yearly academic calendar when international aspirants have to make their visa appointments while planning travel to the U.S. Senators also stated that while some consulates are reopening in the U.S., many are still functioning at lower capacities with limited visa appointment access. Potential students cannot remain certain about processing of visas in a timely manner, enabling them to fly to the country for commencing academics.\nThe Senators have expressed their appreciation on the National Interest Exception for international students, timely visa processing is still a major hurdle. International students visiting the U.S. continue to offer considerable value for the country’s higher education framework and the economy as per the letter. Data garnered from the Association of International Educators indicates how $41 billion was contributed to the national economy by 1 million+ international students at U.S. universities and colleges for 2018-2019 alone.\nAt the same time, the Senators have talked about the further and continuing enrichment of educational and academic experiences of U.S. students due to the influx of international peers. This is tough to accomplish with the online format. There are practical hurdles towards online learning for international students who are not in the U.S. These include differences in time zones, reliable internet and electricity access issues and more. Some classes even require students to attend at unearthly hours as per the Senator group. The group has also highlighted how certain countries restrict access to specific data or sites while the U.S. also limits sharing of specific data with other nations.\nCountless Indian students may benefit from faster visa processing and eventually be able to attend classes this Fall if a positive decision is implemented by the Biden Administration.", "pred_label": "__label__POS", "pred_score_pos": 0.9846060872077942} +{"content": "Severe Hypoglycemia, Cardiac Structure and Function, and Risk of Cardiovascular Events among Older Adults with Diabetes Objective:To assess the association of severe hypoglycemia measured at baseline with cardiovascular disease (CVD) among community-dwelling older individuals with diabetes, a group particularly susceptible to hypoglycemia. Methods:Weincluded older adults with diabetes from the Atherosclerosis Risk inCommunities (ARIC) Study who attended visit 5 (2011–2013, baseline). Severehypoglycemia at baseline was defined using first position ICD-9 codes, fromhospitalizations, emergency department visits, and ambulance calls. We examinedcross-sectional associations ofsevere hypoglycemia with echocardiographic indicesof cardiac structure-function. We prospectively evaluated the risks of incidentor recurrent CVD (coronary heart disease, stroke or heart failure) andall-cause mortality, from baselineto 31 December 2018, using negative binomial and Cox regression models. Results:Among2,193 participants (mean age: 76 years [SD: 5], 57% female, 32% blacks), 79 hada history of severe hypoglycemia at baseline. Severe hypoglycemia wasassociated with a lower left ventricular (LV)ejection fraction (adjusted beta coefficient: -3.7 % [95% CI: -5.5, -1.7]), higherLV end diastolic volume (14.8 ml [95% CI: 8.8, 20.8]), higher E/A ratio (0.11 [95% CI: 0.03, 0.18]), and higher septal E/e’ (2.48 [95%CI: 1.13, 3.82]). In adjusted models, severehypoglycemia was associated with incident or recurrent CVD(incidence rate ratio [IRR]: 2.49 (95% CI 1.4, 4.39]) and all-cause mortality(HR 1.70 [95% CI 1.10, 2.67]) among those without prevalent CVD. Conclusions:Our findings suggest that a history severe hypoglycemia is associated withalterations in cardiac function and is an important marker of futurecardiovascular risk in older adults.", "pred_label": "__label__POS", "pred_score_pos": 0.7190709114074707} +{"content": "Researchers from the University of Arizona have investigated the mineral compositions of two near-Earth asteroids (NEAs), finding potential iron, nickel and cobalt resources exceeding Earth’s global reserves.\nResearchers from the University of Adelaide have discovered how a billion-year-old geological mystery could help to locate the critical minerals of today.\nResearchers have found a holistic ‘cradle-to-grave’ approach to mining life cycle assessments could substantially improve an operation’s environment impacts and feasibility.\nThe University of Queensland has partnered with Rio Tinto and Queensland Alumina to turn bauxite residue known as red mud into a plant sustaining soil.\nResearchers from Pennsylvania State University have discovered a new way to detect terbium, a valuable rare earth element, in difficult environments like acid mine waste.\nThe Australian Research Council has provided $83 million in funding for early career projects in areas including mining equipment, critical minerals processing, and resource technology and services.\nResearchers from MIT have begun unprecedented studies into the environmental effects of sediment plumes from deep-sea mining.\nA researcher from the University of Alberta in Canada has found a coal by-product called nano humus to be highly effective for remediating land and water used in mining.\nResearchers have found a way to replace indium in multiple applications such as electronic devices, anti-reflection mirrors and smart architectural windows.\nThe federal government’s Australia-India Indo-Pacific Oceans Initiative Partnership (AIIPOIP) grant program has given the University of Queensland (UQ) an opportunity to research deep seabed mining.\nFrench scientists have dived deeper than ever before into gold and arsenic’s relationship, improving the understanding of gold concentration and how it can be recovered more effectively.\nThe mining of liquid ore containing copper, gold, zinc, silver and lithium from dormant volcanoes could become a reality following research from Oxford University.\nResearchers have developed an effective method to cost-effectively extract lithium from seawater at a purity of 99.94 per cent while also creating freshwater.\nResearchers from Curtin University have delivered a technology that will significantly enhance the leaching rates for gold ore without using cyanide.\nThe adoption of the Internet of Things (IoT) in the mining sector has highlighted the lack of skills needed to deploy it, according to Inmarsat research program, the Rise of IoT in Mining.\nThe Kimberley region of Western Australia could be rife with platinum resources that are yet to be developed by Panoramic Resources, according to a study that is supported by the state government.\nInmarsat research finds 85 per cent organisations struggle to access reliable connectivity for IoT projects across their mine sites.\nMetallic blue crusts within soil and termite mounds could be a signpost for hidden metal deposits in the southern Pilbara region of Western Australia.\nThe Western Australian Government has declared applications for the Minerals Research Institute’s PhD program open.\nAustralian scientists have discovered gold-coated fungi near Boddington, Western Australia that may offer clues for finding gold deposits.", "pred_label": "__label__POS", "pred_score_pos": 0.653713583946228} +{"content": "Important action is being taken across our state to protect honey bees. However, the public is less aware of the critical role Oregon’s native bees play in pollination and maintaining the healthy environment we all enjoy – nor of the threats they face. Did you know eight different species of native bees are currently listed on the United States Endangered Species List?", "pred_label": "__label__POS", "pred_score_pos": 0.9895981550216675} +{"content": "The COVID-19 pandemic has forced restaurants to adjust how they function. One of the biggest changes is the boost in online ordering — delivery platforms for restaurants offer a great way to give food to customers without direct interaction.\nIf you underestimate the value of online delivery, consider this: in 2020, delivery platforms saw a $3 billion increase in revenue. Whether you run a ghost kitchen or a traditional, brick-and-mortar restaurant, it's important to take advantage of these services. Here are the top 5 delivery services of 2021.\nUberEats\nAvailable in 45 countries, including the United States, United Kingdom and Canada, UberEats is one of the most popular delivery apps out there. It's known for providing a personalized customer experience, which includes photographs, pre-ordering and meal tracking.\nPros\nAdvantages of UberEats include:\nLarge service area:UberEats has over 90 million monthly users. Personalization:UberEats lets restaurants publish photos and create a personalized brand. POS Integrations:UberEats can be integrated with most restaurant technology, including POS systems. Cons\nDisadvantages of UberEats include:\nCommission Fees:In NYC, commission fees can reach up to 20% per order. High Delivery Costs:While UberEats offers a network of delivery drivers, you have to pay a commission to use them. DoorDash\nFounded in 2013, DoorDash is a popular delivery service available in 4,000 cities across North America. DoorDash stands out for its commitment to helping local communities — for example, the company created a $500,000 fund to support economically disadvantaged youth.\nPros\nAdvantages of DoorDash include:\nLarge customer base:Currently, DoorDash has over 18 million customers. Lower costs:For the first 30 days of use, DoorDash doesn't charge restaurants a commission fee. Higher profits:65% of restaurants claim that DoorDash helped them increase profits during the COVID-19 pandemic. Cons\nDisadvantages of DoorDash include:\nChanging fees:DoorDash changes commission rates based on the restaurant, which can lead to unpredictable fees. Limited service area:Currently, DoorDash is only available in North America. GrubHub\nGrubHub is prominent in the United States and can be found in over 4,000 cities across all 50 states. It's also available in London. From advanced search tools to multiple payment options, GrubHub does everything possible to create a positive customer experience.\nPros\nAdvantages of GrubHub include:\nAdvanced search options:GrubHub lets customers search by restaurant, location and cuisine, which widens your reach of people. Strong communication:GrubHub offers a notes feature that facilitates communication between users and restaurants. Popularity:GrubHub has high rankings, including a #1 rating from Tom's Guide. Cons\nDisadvantages of GrubHub include:\nCredit card fees:GrubHub charges credit card processing fees and a 20% marketing fee. Customer fees:GrubHub is known for charging various customer fees, which can deter users. Postmates\nOwned by UberEats, Postmates is available across 3,500 American cities. While it's still its own brand for customers, it has merged with UberEats behind the scenes. It's a great option if you're trying to increase your reach, as it's available 24/7.\nPros\nAdvantages of Postmates include:\nVersatility:Postmates is incredibly versatile and supports restaurants, pharmacies and gas stations. Double services:If you partner with Postmates, your business will also be accessible through UberEats. Low fees:Postmates doesn't charge any credit card processing fees. Cons\nDisadvantages of Postmates include:\nChanging fees:Commission fees vary among restaurants, which can make costs unpredictable. Surge pricing:Postmates increases costs during busy hours, which may deter customers. Seamless\nMaking the list of top 5 delivery platforms, this application is owned by Grubhub. Like its mother company, it's available in over 4,000 US cities and in London. From contactless delivery to online communication, Seamless offers plenty of features to help minimize customer interactions.\nPros\nAdvantages of Seamless include:\nStreamlined deliveries:Seamless streamlines your orders to boost efficiency and speed. Versatility:Seamless supports both local businesses and national restaurant chains. Contact-free delivery:Seamless offers a contactless delivery option, which is ideal for the COVID-19 pandemic. Cons\nDisadvantages of Seamless include:\nLimited reach:Seamless is mainly known for its coverage in NYC, which isn't helpful unless you're based there. Changing delivery fees:Seamless can have unpredictable delivery fees. Which Delivery Applications Do I Use?\nIf you hope to successfully connect with new audiences, you should take advantage of all these apps. This is especially important for ghost kitchens, as online ordering is their main source of revenue. On the downside, it can be difficult to manage multiple services. Each delivery applications provide restaurants with a tablet — the more tablets you have, the higher the chance of mistakes.\nTo protect your kitchen's reputation and boost efficiency, it's advisable to streamline orders using an application like Cuboh. In addition to sending multiple delivery platform orders to a single tablet, Cuboh can integrate with your POS system and facilitate communication with delivery drivers. Learn more by booking a demo today.", "pred_label": "__label__POS", "pred_score_pos": 0.962797224521637} +{"content": "The recommendations the InfantRisk Center provides are not meant to replace medical advice from your physician. The ultimate decision to breastfeed while taking medications should be based on an informed decision including available data, discussions between a mother, her physician, and the infants’ pediatrician. The decision to take medications during pregnancy should be based available data and a discussion between a mother and her OB/GYN.\nMomo: There's not much data on Effexor, that is true. What we have suggests levels in milk are low to modes (6-8%) and that continued breastfeeding after delivery might be beneficial. See below.\nAs for other suggestions, Duloxetine is a suggestion. Sertraline(Zoloft) and Escitalopram(Lexapro) are the two most popular for depression, but may not work for you.\nTom Hale Ph.D.\nFrom MMM, 2019:\nHowever, recent data (MedWatch, FDA) has suggested that infants exposed in utero to various serotonin reuptake inhibitors such as venlafaxine, may have adverse effects immediately upon delivery. These include: respiratory distress, cyanosis, apnea, seizures, temperature instability, etc. It is not known if these adverse events are due to a direct toxic effect of venlafaxine on the fetus, or due to a discontinuation (withdrawal) syndrome. Studies have shown that these adverse effects may be partially relieved with venlafaxine received through breastmilk.[1]\n1.Koren G, Moretti, Kapur B. Can Venlafaxine in Breast Milk Attenuate the Norepinephrine and Serotonin Reuptake Neonatal Withdrawal Syndrome? JOGC 2006 April; 28(4):299-302.", "pred_label": "__label__POS", "pred_score_pos": 0.5945106148719788} +{"content": "The National Archives and Records Administration (NARA) released a 2022-2026 Strategic Plan draft to maximize digital records’ access and availability, including a top-line goal of digitizing a half billion pages of records.\nNotably, the strategic plan draft introduces a future vision of all-digital records, and more equitable access and availability for underserved communities.\nThe 2022-2026 Strategy Plan draft focuses primarily on technology, digitization of records, and ensuring equitable access. According to the draft, those focus areas come from the agency’s vision of being recognized as a supplier of “cutting-edge access to extraordinary volumes of government information and unprecedented engagement to bring greater meaning to the many different American experiences.”\nThe draft strategic plan lays out the agency’s objectives for improving equity of digital records, providing world-class customer experiences all around, and accelerating agency IT modernization. These objectives are becoming particularly crucial to NARA, as the agency will no longer accept paper records by the end of this year. And with an increasing digital archive, NARA wants to reach more users, especially those from previously underserved communities.\nTo implement a digital infrastructure, NARA plans by 2026 to digitize 500 million pages of records and make them publicly available online, ensure that 95 percent of customer requests are resolved within the promised time, and organize metadata tagging efforts to promote equity for records related to underrepresented communities.\nAdditionally, NARA pledges to interact with traditionally underserved communities and work with these communities to identify archived records significant to them. Once identified, they will be prioritized for archival processing and describing, digitizing, and accessing online. “We’re at the beginning of a process to build new relationships with underserved communities, and this draft plan reflects our intent to maintain and foster those relationships over time,” the plan states.\nNARA on August 6 released an invitation for comments to gather feedback from agencies and the public on the plan’s current state. Comments are due by August 20.", "pred_label": "__label__POS", "pred_score_pos": 0.9834966659545898} +{"content": "Abstract\nLipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice. Physiol Genomics 52: 314–321, 2020. First published July 6, 2020; doi:10.1152/physi-olgenomics.00118.2019.—Lipocalin 2 (Lcn2) is a multifunctional innate immune protein that limits microbial overgrowth. Our previous study demonstrated that the gut microbiota directly induces intestinal Lcn2 production, and Lcn2-deficient (Lcn2\n-/-) mice exhibit gut dysbiosis. Coincidentally, gut dysbiosis is associated with metabolic syndrome pathogenesis, and elevated Lcn2 levels has been considered a potential clinical biomarker of metabolic syndrome. Yet whether Lcn2 mitigates or exacerbates metabolic syndrome remains inconclu-sive. Our objective was to determine whether Lcn2 deficiency-in-duced compositional changes in gut microbiota contribute to gain in adiposity in aged mice. Utilizing Lcn2 -/- mice and their wild-type (WT) littermates, we measured metabolic markers, including fasting blood glucose, serum lipids, fat pad weight, and insulin resistance at ages 3, 6, and 9 mo old. Relative to WT mice, aged Lcn2 -/- mice exhibited a gain in adiposity associated with numerous features of metabolic syndrome, including insulin resistance and dyslipidemia. Surprisingly, supplementation with a high-fat diet did not further aggravate metabolic syndrome that spontaneously occurs in Lcn2 -/- mice by 6 mo of age. Interestingly, chow-fed Lcn2 -/- mice displayed marked differences in the bacterial abundance and metabolomic profile of the gut microbiota compared with WT mice. Overall, our results demonstrate that Lcn2 is essential to maintain metabolic and gut microbiotal homeostasis, where deficiency induces spontaneous delayed onset of metabolic syndrome.\nOriginal language English (US) Pages (from-to) 314-321 Number of pages 8 Journal Physiological genomics Volume 52 Issue number 8 DOIs State Published - Aug 2020 All Science Journal Classification (ASJC) codes Physiology Genetics", "pred_label": "__label__POS", "pred_score_pos": 0.7393465042114258} +{"content": "Can’t decide between quality, low-volatility, high-alpha? Why not buy all of them?\nOur previous post discussed how you can use the historical performance of different factors to avoid falling into a factor-trap. However, can factor investing be further simplified?\nThe NSE Strategy Indices\nThe NSE has published a whole library of factor indices. Some of them are\npure factors – like quality, low-volatility, etc – and some are hybrids – like alpha-quality-low-volatility (sort of like a shampoo-conditioner-face-wash 3-in-1.) You can explore their website if your curious.\nThe question is, what if you just took quality, low-volatility and high-alpha (a proxy for momentum) and just equal weighted it? Why choose when you can have all? This is the essence of the Multi-Factor approach to factor investing.\nEqual-weighted Factor Portfolio\nEven if you did a quarterly rebalance, you did better than NIFTY 50.\nSince 2010, an equal-weight alpha/low-vol/quality/value factor portfolio gave an annualized return of 12% vs. NIFTY 50’s 8.88%.\nWhile alpha and low-vol are price-based factors, quality and value are based on company fundamentals. What if, we just equal weighted the price-based factors?\nEqual-weighted Alpha and Low-Volatility Factor Portfolio\nGiven the out-performance of the low-volatility factor, we see a significant boost to an equal weighted alpha/low-vol portfolio compared to equal weighting all the factors.\nTo summarize returns since 2010,\nequal-weight all factors: 12.02%\nequal-weight only alpha and low-vol: 13.76%\nNIFTY 50: 8.88%\nCaveats\nBefore transaction costs, we see that factor indices have beaten the NIFTY 50, historically. However, investors should bear these points in mind while looking at index back-tests:\nIndex Inception – the date from which the index was constructed (since 2005.)\nLaunch – the date on which the index was launched (in 2018.)\nInvested – the date from which a significant amount of money gets invested in the index (in 2019.)\nRe-balance frequency – how often does the index rebalance?\nAt launch, these indices have incorporated over 13 years of historical data. One can’t discount the possibility that there might be some over-fitting to increase their marketability.\nTypically, index performance dips once the AUM crosses a tipping point. And given that India has a 0.1% STT (Securities Transaction Tax,) the higher the re-balance frequency, the worse the performance.\nThe true test of these indices will occur when real money is invested in them over two or three complete cycles.\nConclusion\nBoth Factor Rotation and Multi-Factor approaches have their pros and cons. However, the one thing that remains common is that these take time to play-out. There are huge year-over-year variances in performance and investors need to stick to an approach long enough for alpha to emerge.", "pred_label": "__label__POS", "pred_score_pos": 0.7350542545318604} +{"content": "As scheduled, Patrick and I, along with Ocheung Ivan, the intern, and Walter our driver, ventured back to Palaro Sub County to check on the progress of the latrine pit. In just two days after the planning meeting, the parents had managed to make more than a meter’’s depth before striking the water line and had paused there to discuss the next course of action.\nWe arrived late in the afternoon due to morning repairs to our left rear axle on our company Landcruiser which had been subjected to multiple trips to Palaro on a less than desirable roadway. Due to the bumpy, pothole, and rut filled uneven road with ditches for shoulders, we pulled over twice to tighten the battery in place as it was coming lose due to the steady bouncing over the Mars-like terrain. A roadside motorcycle shop had the proper spanning wrench to tighten down the battery, and we continued to Abaka Primary School after two short delays.\nAfter surveying the water-logged latrine pit that the parents broke ground on that morning, Patrick explained that the progress was good for a mere half day’s time and that the water would be easily drained from the pit by the next day. Seems the ground slopes from west to east and water drains toward to this end of the school, and the encounter with the waterline was to be expected.\nTo ensure a proper understanding between all parties involved on the construction and management of the latrine, a small meeting between Patrick of GDPU, the head teacher, the school manager, the contractor, and myself was conducted to go over the MOU (Memorandum of Understanding).\nThe MOU is a basic contractual agreement between the contractor, the school, and GDPU, with me serving as a witness for The Advocacy Project. Dating the 26\nth of June through the expected completion date of August 14 th, David Kinyera will construct a four stance, drainable latrine with a girl’s changing room, as requested in the previous meeting. A 1.5-meter-wide, 40-meter-long walkway will allow for easy access for those students using a wheelchair for mobility. Handrails, ramps, and a hand washing water tank at the appropriate height for wheelchair users will satisfy the specifications desired by the school, the parents, GDPU, and AP.\nOne of the crucial parts of the MOU is laying the responsibility of the water supply, daily monitoring of construction, and security of materials on Abaka school itself. They will also be responsible for conducting awareness workshops with parents, teachers, and the PTA to improve attitudes toward the inclusion of children with disabilities and a steady stream of support and monitoring to ensure their inclusion in the school and hopefully the community at large.\nLastly, there was an emphasis on open, honest, and frequent communication between the contractor, the school, and GDPU to avoid misunderstandings. Transparency and clarity were called upon to resolve any disputes on construction, materials, costs, or material handling, that would include the GDPU board, the contractor, and a senior staff member of the Abaka Primary School. All parties involved desire this project to proceed successfully without delay and within the given timeframe, and if the cooperation and communication is carried from the initial meeting through all stages of construction, The Abaka Primary School Latrine Project will be a success.\nPosted By Spencer Caldwell (Uganda)\nPosted Jun 27th, 2019", "pred_label": "__label__POS", "pred_score_pos": 0.5711814165115356} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nOn June 30, 2021 the National Center on Afterschool and Summer Enrichment (NCASE) facilitated the webinar,\nSupporting and Promoting Mental Health in Out-of-School Time. During the webinar, NCASE introduced a new Voices from the Field brief which shares research\nThe Help Kids Recover website offers important information about federal stimulus funding available through the American Rescue Plan including the funding apportionment per state, examples of how states are using recovery funding, examples of partnerships in action at different levels (e.g., state, school district, school), contacts for afterschool state networks, and evidence-based strategies.\nThis webinar provides an overview of opportunities provided by the federal education funding from the American Rescue Plan, to help children re-engage, re-connect, and recover. The overview describes how much funding is available, how much has been distributed to state departments of education, and what evidence-based interventions are allowed.\nThis webinar, facilitated by Attendance Works, explores how schools, public agencies, and community partners can use attendance and participation data to organize and tailor summer programs. It suggests a 4-step framework: (1) establish a team; (2) identify priority groups of students to reach; (3) craft engagement strategies; and (4) reflect, learn, and improve.\nThe National Summer Learning Association has provided more than 40 webinars called the Voices of Summer Webinar Series. The webinars were held between spring 2019 and spring 2021. Presenters include national thought leaders, program providers offering promising practices, and researchers.\nEarly childhood mental health consultation (ECMHC) is an increasingly popular strategy for improving early childhood classroom climates and reducing suspensions and expulsions. This webinar explores findings from a recent research report from Yale Child Study Center on Ohio's Early Childhood Mental Health Consultation system.\nThis webinar series explores tools, tips, strategies, and resources for programs to deliver high-quality virtual programs. The first webinar is called Transforming from Virtual Bleh to Virtual Yeah! It offers a wealth of concrete tips to provide structured and consistent programming, increase student engagement, and battle virtual burnout, plus a review of online tools.\nThis webinar series explores the importance of trauma-informed and healing-centered approaches in out-of-school time settings and the role they can play in helping youth manage and recover from trauma.\nThis toolkit includes resources that will help build child care supply. It includes six steps: (1) assess and plan; (2) identify resources; (3) generate awareness; (4) develop strategies; (5) implement your plan; and (6) evaluate and implement. The concepts build on recognized strategic planning principles and include stories of success. This resource supports the COVID-19 response.\nWith many school districts providing partial or full online learning, there is increased need for child care for working parents. This collection of online resources includes videos of providers, and identifies recommendations for new supports on funding, shared planning and decision-making, and technical supports. This resource supports the COVID-19 response.", "pred_label": "__label__POS", "pred_score_pos": 0.6533668041229248} +{"content": "Venture Cafe will host an evening of talks on the expanding needs of professional women in Japan. Faced with the most rapidly aging population in the world, Japan’s workforce needs more women to meet future demand. However, 40% of Japanese women cut their careers short after childbirth and the work culture has lead to an increase in mental health issues. The solution lies in offering women more affordable, easy-to-access services designed to ensure their safety, health, and wellbeing throughout their careers. SOMPO Digital Lab, the innovation group of Tokyo-based insurance and health conglomerate Sompo Holdings, is looking to partner with digital health startups focused on women’s health.\nThis event will offer innovators a glimpse into the challenges faced by working women in Japan as well as the opportunity to propose solutions at a follow-up event later this year. The evening will also feature a panel of SOMPO’s current digital health partners as well as Japan experts who will offer valuable insights on entering the Japanese market.\nFor complete details, please visit www.vencaf.org/femtechjapan", "pred_label": "__label__POS", "pred_score_pos": 0.8048220276832581} +{"content": "Data Availability StatementData can be found upon request. teaching, and carrying out a cool-down period. Analyses exposed a significant increase in OT immediately after a high-intensity training, returning to baseline levels following a cool-down period. Additionally, although no significant difference between beginner and advanced martial artists was found, a significantly higher increase in salivary OT followed ground grappling, as compared to punch-kick sparring, indicating an added benefit of close contact tactile interaction. These results suggest that the reportedly socially beneficial effects of traditional martial arts may be in part mediated by OT release and underscore the potentially therapeutic applications of these methods for disorders involving social dysfunction, such as autism, conduct problems, or schizophrenia. component (high-intensity, free-style friendly tournament) in each class. However, whereas in DSJJ typically involves punch-kick sparring, BJJ focuses on ground grappling. Thus, we sought to address the following three questions. First, provided the first recommendations linking physical OT and workout, we examined if the high-intensity aerobic teaching during fighting techinques would bring about exercise-induced raises in OT. Second, as newbie and advanced individuals experienced different degrees of prior fighting techinques teaching considerably, we looked into whether this may result in differential OT reactions. Finally, we analyzed whether the much longer close contact period occurring during floor grappling would bring about higher OT response. LEADS TO examine the OT response between newbie Cycloheximide irreversible inhibition and advanced martial performers, LMM was carried out, with trainee level (newbie vs. advanced), period of saliva collection (baseline, peak-training, cool-down), and their relationships as fixed elements, and an intercept for subject matter as a arbitrary element. These analyses proven a significant aftereffect of period of saliva collection, (2, 120)?=?12.0, (1, 60)?=?0.79, (2, 120)?=?0.10, (sparring vs. grappling), period of saliva collection (baseline, peak-training, cool-down), and their relationships had been entered as set elements and an intercept for subject matter as a arbitrary element. These analyses exposed a significant aftereffect of period of saliva collection, (2, 132)?=?15.6, didn’t reach statistical significance, (1, 66)?=?3.47, was significant, (2, 132)?=?4.69, didn’t reach statistical significance, the interaction between time Cycloheximide irreversible inhibition of saliva type and assortment of randori was significant, reflecting a big change in OT response between sparring and grappling rigtht after peak-training. Discussion The existing research was a pioneering work to examine whether a program of traditional fighting techinques teaching would induce Cycloheximide irreversible inhibition a rise in OT amounts. We discovered a substantial upsurge in OT after a high-intensity program instantly, time for baseline levels carrying out a cool-down period. Additionally, although no factor between newbie and advanced martial performers was found, a substantial interaction between period of saliva collection and kind of indicated that grappling resulted in a significantly higher OT increase than sparring. Given the beneficial effects of traditional martial arts on cognitive and psychological functions30,31, and the reported therapeutic effects of exogenous administration of OT in disorders of social dysfunction, such as autism and schizophrenia12C14, this readily available, non-invasive training program may have wide Cycloheximide irreversible inhibition implications for physical fitness and community health. Several potential mechanisms may underlie OT release during may, in itself, lead to increases in OT. However, another more complex social mechanism that may contribute to OT increase during is the ability of OT to increase the salience of social information33. Early studies in sheep, for example, reported that OT promotes the selective olfactory recognition of offspring4. In humans, administered OT was found to increase gaze toward eye regions, Cycloheximide irreversible inhibition which are considered the most socially communicative part of faces34. Moreover, several neuroimaging studies have shown that the administration of OT can have effects on socially-relevant brain areas including the amygdala35 and the ventral tegmental area33, and studies using fMRI36 found that the tendency toward increasing gaze to the eyes is associated with an increased coupling of amygdala and superior colliculi activity, assisting the look at that OT biases a person toward cultural visual info. These key top features of improved cultural information salience are necessary in the social synchrony, which includes been connected with OT function. The OT molecule was been shown to be critically associated with repeated synchronous behaviors in a variety of living microorganisms, from coordination of reproductive behavior in roundworms to flocking behavior in birds37. Furthermore, in human beings, it’s been proven that improved degrees of OT are linked to improved synchronous gaze Rabbit Polyclonal to NMUR1 between moms and their kids38 and neural synchrony during cultural coordination39. Thus, the focus on dyadic synchronous behaviors in fighting techinques may donate to raises in salivary OT. Of course, additional studies are needed to examine whether this synchronous behavior common in martial arts results in greater OT release, as compared to other, solitary physical activities described above20. It should be noted that although the presumably OT-mediated bias toward social information has commonly been associated.", "pred_label": "__label__POS", "pred_score_pos": 0.5986832976341248} +{"content": "NET energy has developed an original and comprehensive approach for energy system optimization, providing a much-needed systems approach to energy applications. NET energy has developed systems that include renewable power generation, conversion and storage including: wind, solar photovoltaic power, batteries, fuel cells, and Hydrogen.\nNETenergy‘s goal is to minimize the cost and maximize the reliability of renewable energy in stationary and transportation applications.", "pred_label": "__label__POS", "pred_score_pos": 0.7334357500076294} +{"content": "Bank of America is installing solar panels across multiple locations. Our Onsite Solar Initiative is using the sun’s power to bring renewable energy to financial centers, ATMs, office locations and operational buildings, resulting in reduced energy costs and greenhouse gas emissions.\nThe initiative is expected to generate more than 25 megawatts of renewable electricity, which will directly power the bank’s operations in select locations with clean, renewable energy.\nThis initiative is in support of our goal to use 100 percent zero carbon electricity by adding new renewables to reduce operational footprint.\nGoing solar\nTo date, more than 20 financial centers in Arizona, California, Florida, Illinois, Missouri, North Carolina, Pennsylvania, Texas and Virginia, three ATMs in California, North Carolina and Virginia, and two office locations, one each in Nevada and North Carolina, are already benefitting from the emissions savings from the bank’s onsite solar installations. Through 2023, the company is expected to add more than 60 solar installations across its operations.\n“Having solar energy onsite to power our facilities is part of our responsible growth strategy and reduces our operational impact on the environment,” said Andrew Plepler, global head of Environmental, Social and Governance at Bank of America. “This work, along with our LEED certifications at our financial centers and other locations, provides not only an innovative experience for our clients, but is key to our role in helping to accelerate the transition to a sustainable, low-carbon economy while supporting the communities where we work and live.”", "pred_label": "__label__POS", "pred_score_pos": 0.9566226601600647} +{"content": "This ambitious project will likely be the most visible initiative of MOPA’s initial initiatives. Dustbins will be placed in identified locations in the capital, Male’, followed by a mass media campaign to educate and raise awareness on safe disposal of trash, especially plastic waste.\nAs part of this project, a daily collection service will be initiated to pick out PET bottles and other plastic waste from the designated bins, sorting and storage of the plastic, and ultimately moving to recycling facilities.\nMOPA foresees that this project will involve strong stakeholder support and participation, including government and council assistance, haulers involvement and PET recycling specialists.", "pred_label": "__label__POS", "pred_score_pos": 0.9895859956741333} +{"content": "< Terug naar vorige pagina\nPublicatie Productive lifespan and resilience rank can be predicted from on-farm first parity sensor time series but not using a common equation across farms Tijdschriftbijdrage - Tijdschriftartikel\nA dairy cow’s lifetime resilience and her ability torecalve gain importance on dairy farms, as they affectall aspects of the sustainability of the dairy industry.Many modern farms today have milk meters and activitysensors that accurately measure yield and activityat a high frequency for monitoring purposes. Wehypothesized that these same sensors can be used forprecision phenotyping of complex traits such as lifetimeresilience or productive life span. The objective of thisstudy was to investigate whether lifetime resilience andproductive life span of dairy cows can be predicted usingsensor-derived proxies of first-parity sensor data.We used a data set from 27 Belgian and British dairyfarms with an automated milking system containingat least 5 yr of successive measurements. All of thesefarms had milk meter data available, and 13 of thesefarms were also equipped with activity sensors. Thissubset was used to investigate the added value of activitymeters to improve the model’s prediction accuracy.To rank cows for lifetime resilience, a score was attributedto each cow based on her number of calvings, her305-d milk yield, her age at first calving, her calvingintervals, and the DIM at the moment of culling, takingher entire lifetime into account. Next, this lifetimeresilience score was used to rank the cows within theirherd, resulting in a lifetime resilience ranking. Based onthis ranking, cows were classified in a low (last third),moderate (middle third), or high (first third) resiliencecategory within farm. In total, 45 biologically soundsensor features were defined from the time series data,including measures of variability, lactation curve shape,milk yield perturbations, activity spikes indicating estrousevents, and activity dynamics representing healthevents (e.g., drops in daily activity). These features,calculated on first-lactation data, were used to predictthe lifetime resilience rank and, thus, to predict theclassification within the herd (low, moderate, or high).Using a specific linear regression model progressivelyincluding features stepwise selected at farm level (cutoffP-value of 0.2), classification performances werebetween 35.9 and 70.0% (46.7 ± 8.0, mean ± SD) formilk yield features only, and between 46.7 and 84.0%(55.5 ± 12.1, mean ± SD) for lactation and activityfeatures together. This is, respectively, 13.7 and 22.2%higher than what random classification would give.Moreover, using these individual farm models, only 3.5and 2.3% of cows were classified high when they wereactually low, or vice versa, whereas respectively 91.8and 94.1% of wrongly classified animals were predictedin an adjacent category. The sensor features retainedin the prediction equation of the individual farms differedacross farms, which demonstrates the variabilityin culling and management strategies across farms andwithin farms over time. This lack of a common modelstructure across farms suggests the need to considerlocal (and evidence-based) culling management ruleswhen developing decision support tools for dairy farms.With this study we showed the potential of precisionphenotyping of complex traits based on biologicallymeaningful features derived from readily available sensordata. We conclude that first-lactation milk andactivity sensor data have the potential to predict cows’lifetime resilience rankings within farms but that consistencybetween farms is currently lacking.\nTijdschrift: Journal of Dairy Science\nISSN: 0022-0302\nIssue: 8\nVolume: 103\nPagina's: 7155 - 7171\nAantal pagina's: 17\nJaar van publicatie:2020", "pred_label": "__label__POS", "pred_score_pos": 0.6594655513763428} +{"content": "Malaysia is currently undergoing a transformation and aspires to achieve Smart City status. A Smart City is defined as a dynamic development approach enabled by smart infrastructure, services, systems, and people.\nCitizen centricity is at the heart of making a smart city a reality. The Smart Services development plan is guided by the philosophy of promoting stronger social inclusion, actively involving and engaging citizens, and addressing urban challenges using technology as a key enabler. By leveraging technology, the Smart Services development plans aim to address top-priority challenges, stimulate investments, enhance efficiency and create next-generation jobs to fuel sustainable growth and enhance the quality of life for all residents in the country states.\nCableONE Solutions: Safety & Security Solutions Smart Parking System Smart Transportation System Smart City Solutions Smart Home Solutions", "pred_label": "__label__POS", "pred_score_pos": 0.9954853653907776} +{"content": "As caregivers, community members, and early childhood educators, we have a responsibility to ensure each child, family, and caregiver is safe from racism and discrimination and has equitable opportunities to thrive.\nIn order to do this, we must begin with ourselves. Set aside time in your day to do a personal inventory. What thoughts, feelings, and behaviors have you contributed to upholding systems of racism? What assumptions are you making? What actions or inactions have you taken that contribute to systems of oppression?", "pred_label": "__label__POS", "pred_score_pos": 0.8801089525222778} +{"content": "or with a gathering of individuals who have comparable challenges. Regularly \"schoolwork\" is appointed for members to finish between meetings. Prescription Prescription doesn't fix tension issues yet can assist with diminishing side effects. Medicine for tension is endorsed by specialists, like a therapist or essential consideration supplier. A few states additionally permit analysts who have gotten particular preparing to recommend mental prescriptions. The most well-known classes of prescriptions used to battle tension issues are against uneasiness drugs (like benzodiazepines), antidepressants, and beta-blockers. Legal lean Store Hostile to Anxiety Medications Hostile to uneasiness prescriptions can assist with diminishing the indications of tension, alarm assaults, or outrageous dread and stress. The most well-known enemy of uneasiness drugs are called benzodiazepines. In spite of the fact that benzodiazepines are now and again utilized as first-line medicines for summed up tension problem, they have the two advantages and disadvantages. A few advantages of benzodiazepines are that they are compelling in assuaging tension and produce results more rapidly than stimulant meds regularly endorsed for nervousness. A few disadvantages of benzodiazepines are that individuals can develop a resilience to them in case they are assumed control throughout an extensive stretch of time and they might require increasingly elevated dosages to get a similar impact. Certain individuals might even become subject to them. To stay away from these issues, specialists ordinarily recommend benzodiazepines for brief timeframes, a training that is particularly useful for more seasoned grown-ups, individuals who have substance misuse issues, and individuals who become subject to drug without any problem. On the off chance that individuals abruptly quit taking benzodiazepines, they might have withdrawal indications, or their uneasiness might return. Consequently, benzodiazepines ought to be tightened gradually. At the point when you and your primary care physician have concluded the time has come to stop the prescription, the specialist will help you gradually and securely decline your portion. For long haul use, benzodiazepines are frequently viewed as a second-line treatment for tension (with antidepress Particular mutism: A to some degree uncommon confusion related with uneasiness is specific mutism. Particular mutism happens when individuals neglect to talk in explicit social circumstances regardless of having typical language abilities. Particular mutism typically happens before the age of 5 and is regularly connected with outrageous bashfulness, dread of social shame, habitual characteristics, withdrawal, sticking conduct, and fits. Individuals determined to have specific mutism are regularly likewise determined to have other uneasiness issues. Being outside of the home alone Individuals with agoraphobia regularly keep away from these circumstances, to a limited extent, since they believe having the option to leave may be troublesome or inconceivable in the occasion they have alarm like responses or other humiliating side effects. In the most extreme type of agoraphobia, an individual can become housebound.", "pred_label": "__label__POS", "pred_score_pos": 0.7640715837478638} +{"content": "Patent search is an unavoidable element of any successful invention today. The primary marketable component of patents is their exclusivity, so inventors and other entities need to know their product will not infringe upon inventions already in the market. This is also relevant for R&D departments- knowing what competitors are doing and what inventions they already have on their portfolio helps with targeted research, allowing clients to maximize their patent value. This is particularly critical in the Telecommunications field, where multiplicity of inventions and incremental innovations make the landscape a potential minefield.\n1 Answers", "pred_label": "__label__POS", "pred_score_pos": 0.7846804857254028} +{"content": "2020 Volume 14 Issue 5 Pages 232-238\nThe objective of this study was to explore the factors associated symptoms of depression among pregnant women with gestational diabetes mellitus (GDM) in Japan. This cross-sectional study was conducted at a hospital in Toyota, Japan, from January 2015 to June 2016. Pregnant women who visited the hospital and were diagnosed with GDM in the second trimester were enrolled. We analyzed depression symptoms using the Centers for Epidemiological Studies Depression Scale (CES-D) and considered related factors of depression symptoms, such as dietary intake and daily walking. Dietary intake during the past month was assessed using a brief self-administered diet history questionnaire, and daily walking was assessed using an accelerometer. The prevalence rate for GDM was 8.8%, and 25 pregnant women with GDM were analyzed. The CES-D was not significantly correlated with pre-pregnancy BMI, postprandial plasma glucose, hemoglobin A1c, and the number of steps walked. In contrast, a significant negative correlation was observed between the CES-D score and intake of fish with bones, simmered fish, pickles, green leaves, mushrooms, and green tea. Furthermore, a significant positive correlation was found between Coke\n® and CES-D scores. For nutrient intake, a significant negative correlation was found between the CES-D score and vitamin K, folate, and β-carotene levels. The present study suggests that depression symptoms among pregnant women with GDM in the second trimester may be associated with diet.", "pred_label": "__label__POS", "pred_score_pos": 0.9999396800994873} +{"content": "Client Consultation\nComplimentary discussions to identify concerns and limitations which could create financial challenges.\nPolitical upheaval, pandemics, and financial market changes can create unstable economic environments. Many companies struggle without a pathway to improvement and resolution. Most business executives have never studied or experienced distressed situations and need a partner to guide them.\nWe are Business Advisors with a history of consulting in turnaround situations. Our goal is to stabilize your organization, discuss alternatives, and help you return to growth. We work with debtors, lenders, creditors, trustees, and attorneys to help provide strategic and transparent solutions for companies in distress. Turnaround and Restructuring Services are sometimes the best way to maintain a business’ worth and our specialists focus on helping all parties weather difficult times, professionally and expeditiously.\nIt is best to engage early on in a distressed situation to preserve cash and have time to implement change, avoiding or minimizing negative outcomes.\nComplimentary discussions to identify concerns and limitations which could create financial challenges.\nA review of all loan and security agreements and amendments to identify lender covenants, reporting requirements, borrowing base calculations, and other lender requirements. Prepare projections to forecast covenant compliance.\nWe identify concerns, determine strategic alternatives to turnaround results, and develop action plans to ultimately avoid crisis situations. To keep services cost-effective, engagements are customized and may include:\nImplementation of strategies developed in the initial assessment that generally cover one quarter or 90 days. At the conclusion, management will receive an exit report including further recommendations and financial forecast model instructions.\nIf an initial assessment reveals the need for capital or an exit strategy, we have the ability to work with stakeholders and trusted providers to refinance or sell the business. Capital options include debt or equity or working out a deal with a strategic partner. Together, we can discover the potential options and determine what is viable, as well as the timetables to complete such work.\nPKF Mueller offers customized lender services including:\nPKF Mueller offers customized services including:", "pred_label": "__label__POS", "pred_score_pos": 0.7179368734359741} +{"content": "Abstract\nWith a single microtubule attachment, budding-yeast kinetochores provide an excellent system for understanding the coordinated linkage to dynamic microtubule plus ends for chromosome oscillation and positioning. Fluorescent tagging of kinetochore proteins indicates that, on average, all centromeres are clustered, distinctly separated from their sisters, and positioned equidistant from their respective spindle poles during metaphase. However, individual fluorescent chromosome markers near the centromere transiently reassociate with their sisters and oscillate from one spindle half to the other. To reconcile the apparent disparity between the average centromere position and individual centromere proximal markers, we utilized fluorescence recovery after photobleaching to measure stability of the histone-H3 variant Cse4p/CENP-A. Newly synthesized Cse4p replaces old protein during DNA replication. Once assembled, Cse4-GFP is a physically stable component of centromeres during mitosis. This allowed us to follow centromere dynamics within each spindle half. Kinetochores remain stably attached to dynamic microtubules and exhibit a low incidence of switching orientation or position between the spindle halves. Switching of sister chromatid attachment may be contemporaneous with Cse4p exchange and early kinetochore assembly during S phase; this would promote mixing of chromosome attachment to each spindle pole. Once biorientation is attained, centromeres rarely make excursions beyond their proximal half spindle.", "pred_label": "__label__POS", "pred_score_pos": 0.9530074000358582} +{"content": "A hospital in an area in south-west Pakistan where many Afghans have taken shelter has received a facelift thanks to the United Nations High Commissioner for Refugees and its partner, the American Refugee Committee (ARC).\nThe Refugee Affected and Hosting Areas (RAHA) scheme was inaugurated at District Headquarters Hospital in Pishin, Balochistan province, yesterday.\nUNHCR contributed nearly $14,000 for the upgrade of the reproductive health-care unit – including a new labour room – at the facility, where over two-thirds of patients are believed to be Afghan. For its part, the ARC purchased medical equipment and hygiene kits and trained staff.\n“Afghan refugees have been part of the local communities for over 25 years, and the RAHA project is our ongoing programme that is aimed at compensating the local communities that have been affected due to the prolonged presence of refugees,” said John Soleck, who heads the UNHCR office in Quetta.\nMost of the roughly 400,000 registered Afghans in Balochistan live in urban settlements, and the new initiative – which also will cover the North West Frontier Province – seeks to help both the refugees and their host communities by boosting their health, education and water and sanitation facilities.\nUnder this programme, UNHCR has also contributed to other projects in Balochistan, including improving healthcare for mothers and newborns.", "pred_label": "__label__POS", "pred_score_pos": 0.5275682210922241} +{"content": "Qrious, Spark’s data, analytics and AI business, has today announced that it is investing significantly in the Wellington market. This investment is targeted at meeting a growing demand from Government organisations and Wellington-based enterprises for data transformation services and for post-Covid acceleration of digital innovation. It will see a rapid expansion of Qrious’ Wellington consulting practice, as well as nurturing a talent pipeline to build its data, analytics and AI capabilities.\n\"Data and digital technologies are the essential skills we need to build a digital economy\", says Qrious CEO Nathalie Morris. \"We believe that the builders of the future are in tech - and we want to help pave the way to that future. Qrious is taking a leading role in data innovation, by investing in our Wellington-based capability to match our existing strength in Auckland.\"\nNathalie explains, \"We are fostering the complete lifecycle of data, analytics and AI engineers - from high school, where career decisions are first made, through to universities, Qrious internship programmes, first-job mentoring, and by providing career-defining, cutting-edge projects for seasoned practitioners.\"\nQrious is seeing a significant increase in clients, particularly in the Government sector, who need support with projects spanning data, AI and intelligent applications. \"This work requires a diverse range of skilled employees who are passionate about delivering data innovation that can transform New Zealand,\" says Nathalie.\n\"More organisations are recognising data as a key enabler to deliver their strategic objectives. We’re also seeing an increasing pace of cloud adoption. Qrious has the skills and experience to help our organisations on their data modernisation journey and ensure these projects are done well.\"\nTo support Wellington’s growth, Qrious has appointed Samir Parekh to the new role of Managing Consultant. Samir has 20-plus years of expertise as a business intelligence and data warehouse consultant, with extensive experience in data strategy and data solution architecture that supports evidence-based decision-making. He will be responsible for building and leading the Wellington data and analytics consulting team.\nSamir believes organisations understand that the future lies in a modern cloud-based data, analytics and AI approach, however they face certain challenges in getting there with their often-legacy data platforms, significant data assets, and concerns around security of data. \"Navigating those challenges requires the right roadmap and skill-set on the ground to deliver - and that’s what we’re here to do,\" says Samir.\nTwo months into his role, Samir is excited for the future: \"No other company in New Zealand is actively curating a team like Qrious that will represent not just the best talent in New Zealand, but world-leading talent, nurtured from the ground up. This is where you want to be to make your mark in data innovation.\"", "pred_label": "__label__POS", "pred_score_pos": 0.6446493864059448} +{"content": "(MENAFN– Finbold) Sovereign Wealth Funds (SWF) continue to grow with more countries opening funds and investing in various products. However, some regions are taking the lead, accounting for a significant share of the global SWF value.\nAccording to data acquired by Finbold, as of October 2021, the global Sovereign Wealth Funds assets under management stand at $10.3 trillion. Asia and MENA regions account for the highest share of $7.8 trillion or 76.06% of the global value. Asia has $4.5 trillion, while MENA holds $3.2 trillion. Europe ranks third with AUM at $1.6 trillion. Other regions with a significant share of the SWF assets include Oceania ($434 billion), North America ($299 billion), Latin America ($31 billion), and Sub-Saharan Africa ($15 billion). Elsewhere, Norges Bank Investment Management (NBIM) ranks the largest sovereign wealth fund globally with $1.3 trillion. The China Investment Corporation (CIC) ranks second at $1.6 trillion, followed by Abu Dhabi Investment Authority (ADIA) at $829 billion. Overall, the ten most significant Sovereign Funds hold 72.01% of global SWFs value at $7.43 trillion. The State Administration of Foreign Exchange (SAFE) at $817 billion followed by The Government PensionInvestment Fund (GPIF) at $744 billion, while Kuwait Investment Authority (KIA) ranks sixth at $693 billion. The Hong Kong MonetaryAuthority (HKMA) accounts for $520 billion, followed by The National Council for Social Security Fund (NSSF) at $452 billion. The Public Investment Fund (PIF) and The Qatar Investment Authority(QIA) rank in the ninth and tenth spots at $430 billion. Asia’s economic growth influences the region’s SWF The report explores some of the driving factors behind Asia’s position in the SWF scene. According to the research report. “Although the Asian region entered the Sovereign Wealth Fund scene more recently, it accounts for a significant share thanks to rapid economic growth in the last two decades. Several countries like China opted for multi-billion funds that are now competing on a global scale. Notably, China stands out considering that most investment portfolios defy traditions by exploring the private sector.” Despite the growth of SWFs globally, the sector is facing several criticisms from the political class. Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.", "pred_label": "__label__POS", "pred_score_pos": 0.9987306594848633} +{"content": "The primary focus of this research is the poorly understood relationship between water insufficiency and broad-scale social change, in the semi-arid lower Salt River Valley, in central Arizona. The overarching research question guiding this research is if water insufficiency could have prompted sociopolitical change among the Hohokam. Specifically, the research investigates if long-term water deficits were a catalyst for the two most consequential transformations in Hohokam history – the Preclassic/Classic transition (A.D. 1070-1100/1150) and the early to late Classic period transition (ca. A.D. 1300).\nThis research used extensive historical aerial photographs and cultural resource management excavation data to complete the largest-scale reconstruction of Hohokam irrigation. These lines of evidence provided exceptional insight into the developmental histories of eight major irrigation systems along the lower Salt River, four of which are newly defined here. Also, historic Salt River streamflow trends are leveraged to refine previously reconstructed annual flow discharges. The irrigation system reconstruction provided the means for estimating irrigation demand through irrigated acreage, and monthly streamflows supplied the amount of water available during key points in the two agricultural cycles per year. Together, irrigation demand and water availability provided necessary data to identify persistent water shortages during Hohokam history between A.D. 740 and 1450.\nThe findings discussed in this dissertation demonstrate that water insufficiency likely had no notable effect related to either the Preclassic/Classic or early to late Classictransitions in the lower Salt River Valley. Instead, there was possibly enough water through time for Hohokam farmers to meet agricultural demands. Three substantial additional insights were gained from this research. First, an extremely large flood, occurring either during the late Colonial or early Sedentary periods, may have profoundly altered irrigation agriculture and social organization in the valley. Second, during at least the Sedentary and Classic periods, Hohokam irrigation was structured into standardized irrigation units (SIU), a far more complex and efficient method of irrigation than previously perceived along the lower Salt. Third, a bedrock reef located near Canal System 2, and not at other lower Salt irrigation systems, is plausibly a determinate in Canal System 2’s longevity.\nContributors\nCreated\n2020", "pred_label": "__label__POS", "pred_score_pos": 0.9638069868087769} +{"content": "The Nevada Rural Housing Authority reported in mid-September that the organization still had funding available for renters seeking assistance for past due rent and utility bills for qualifying applicants in the rural part of the state.\nNRHA is now accepting applications for its CHAP program, which has emergency rental and utility assistance for tenants in Nevada’s 15 rural counties, including Nye and Esmeralda counties.\nAccording to a release from NRHA, tenants who have had a reduction, or loss, of income due to COVID-19 are encouraged to apply to the program. Landlords are able to initiate the application process on their tenant’s behalf.\nNRHA states in a release that rental assistance can cover up to a year of rent and utilities that are past due; any past due balances will be paid before any future payments, the agency states.\nBut assistance is available for rent going forward as well for eligible tenants.\nLandlords can start the application process on behalf of their tenants by going to NVRural.org/COVID\nTenants can also visit the same website to apply for assistance.\n“Tenants experiencing a reduction in or loss of income due to COVID-19 can get assistance on delinquent rent payments and rent payments in the future for anticipated losses of income,” NRHA states in a release. “Assistance can also cover payments such as late fees, security deposits, application fees, hotel costs, utilities and internet fees.”\nNRHA must verify a tenant’s income, and applicants must provide proof of COVID-19-related losses. The list of acceptable situations, though not exhaustive, includes a reduction in work hours, loss of employment, being furloughed from employment during a stay-at-home order or a reduction of income due to reduced business income.\nApplicants can also call NRHA at its dedicated Cares Housing Assistance Program at 775-302-5090 0r at 833-328-0288.\nFor information on the CHAP program in Clark or Washoe counties, separate from the other rural program, head to HTTP://chap.clarkcountynv.gov or HTTP://www.renoha.org/chap\nNRHA serves Nevada’s 15 rural counties and the rural portions of Clark and Washoe counties and assists with homeownership programs, rental services, community development initiatives and an exclusive weatherization program.\nFunding for the rental and utility assistance program comes from Title V of the 2021 Consolidated Appropriations Act.", "pred_label": "__label__POS", "pred_score_pos": 0.8046302199363708} +{"content": "Delivering Reliable Passenger Information in an Unreliable World\n“The industry has shown a remarkable ability to adapt in response to Covid. Given the expectations of increasing technology disruption in the future, how do we ensure we meet rising passenger expectations for more predictable, reliable bus services?”\nThis was one of the questions addressed by an expert panel during a lively Intelligent Transport webinar on 28 September.\nTransport Focus’s Ian Wright explained that while passenger expectations are naturally rising, the core requirements for bus users remain largely the same: affordability, convenience and control.\nBut as Warwick Goodall from PA Consulting explained, in an increasingly disrupted world this places ever more pressure on transport providers. The task today is to reimagine the bus experience, ensuring it is simpler than the car, cheaper than Uber, as green as cycling, and inclusive for all.\nTo deliver this experience, ‘real-time’ information must also evolve, enhancing the passenger experience, while unlocking improvements for bus drivers and greater efficiency for operators and authorities.\nAs Trapeze Group’s Richard Riley explained, technology is already moving in this direction. In the months to come the concept of ‘true’ real-time will emerge, distinguishing between prediction times which can currently be delivered, and instantly available, completely reliable passenger information.\nRichard explained how the linking of schedule and ITS solutions reduces information latency, ensuring that accurate service information reaches the public even through short-term schedule changes.\nMeanwhile, ‘Delta encoding’ is a way of storing or transmitting data in the form of differences between data rather than complete files, which minimises data transfer requirements – ensuring that even the largest and most complex networks can access accurate information through significant service disruption.\nFinally, by harnessing machine learning we can not only deliver information better; we can deliver better information. Completely accurate full journey prediction times – based on historic and current data – will enable passengers to trust the bus at all times, enabling it to remain the cornerstone of their mobility plans.\nDisruption has become a major part of life over the past two years, and most observers expect this to continue in the future. By harnessing ‘true’ real-time information we can upgrade our ability to adapt to a changing world – ensuring buses remain the reliable, sustainable mobility solution for the next 20 years.\nYou can watch the full webinar here\n(c) 1999 - 2021 Trapeze Software ULC. All rights reserved\nTrapeze Group respects your privacy", "pred_label": "__label__POS", "pred_score_pos": 0.9758573770523071} +{"content": "Reflections beyond words: using auto-driven photo-elicitation to explore the pain management programme journey Average rating Cast your vote You can rate an item by clicking the amount of stars they wish to award to this item. When enough users have cast their vote on this item, the average rating will also be shown.Star rating\nYour vote was cast\nThank you for your feedback\nThank you for your feedback\nAuthorsRoberts, Suzanne AdvisorsCureton, Debra\nLawton, Megan\nWard, Gavin\nIssue Date2021-05\nMetadataShow full item record AbstractIn the UK, around one-third to one-half of the population are estimated to be affected by persistent pain, a long-term complex condition which can have serious implications for an individual’s everyday functioning and quality of life. A biopsychosocial approach to care and pain management programmes can be adopted as a treatment option. A growing body of research supports the effectiveness of Acceptance and Commitment Therapy based pain management programmes. This research, however, is based on analyses of pre-post changes in pre-defined outcome measures. Limited qualitative research has focused on programme evaluation and the notion of acceptance. This study aimed to explore the individuals’ everyday experience of change as they progressed through a pain management programme to enhance understanding of the change process from the individuals’ perspective. This study also aimed to establish how auto-driven photo-elicitation can support participants to articulate their pain management journey. Nine participants who were part of a six-week online pain management programme were asked to generate weekly images representing a meaningful change in their pain management. These images were discussed in photo-elicitation interviews at week two, four and six of the programme. Transcripts were analysed using thematic analysis. The findings represented the way participants created meaning associated with changes in their pain management across the three timepoints of data collection. The significance of these time points in relation to pain management were constructed as: (1) Insight and Awareness, (2) Integration and (3) Reframing. All participants described a shift in their perspective towards pain, which appeared to be facilitated by factors of ‘acceptance’ and ‘empowerment’. Auto-driven photo-elicitation was found to ‘invite reflection’ and held ‘therapeutic value’ which facilitated the change process. Photography was found to be an engaging and valuable method for helping individuals articulate their pain management journey. This provides support for the adaptability of pain management programmes and the use of photography to create therapeutic opportunities. PublisherUniversity of Wolverhampton TypeThesis or dissertation Languageen DescriptionA thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the Professional Doctorate in Health and Wellbeing (DProfHW). Collections\nThe following licence applies to the copyright and re-use of this item:\nCreative Commons\nExcept where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International", "pred_label": "__label__POS", "pred_score_pos": 0.6550662517547607} +{"content": "Identify what capabilities you bring to the challenge of being more inclusive and the steps you can take to develop inclusion competencies with the ICI (Inclusion Competencies Inventory). The ICI measures competencies – factors that predict superior performance related to inclusive behavior. The ICI serves as a catalyst that motivates individuals and teams to improve inclusion behaviors.\nFor more information about administering or taking the ICI, please contact us.", "pred_label": "__label__POS", "pred_score_pos": 0.5734828114509583} +{"content": "Joining World Heart Day 2021 is not just a celebration for Sanofi, but more like hoping that they could reach more people and spread awareness about heart diseases and stroke. Sanofi recognizes that this is a unique time especially when the world is still under a pandemic but knowing and learning what steps to do about having a healthy heart is what matters.\n\"It's heartbreaking to see those with comorbidities battle a critical to severe form of the virus- forcing them to put their lives on hold, be isolated from family, friends and people who matters most to them,\" said Amal Makhloufi Benchouk, Sanofi Philippines Country Lead.\nStatistics have shown that 7 out of 10 people are diagnosed with hypertension, and 2 out to 10 hypertension patients die. Sanofi continues to respond to the challenge of dealing with comorbidities during this time, by emphasizing the need to address the lack of awareness and limited access to cardiovascular disease management.\n\"Cardiovascular Disease remains the number 1 killer in the world, resulting in about 18.6 million deaths worldwide and over 520 million people globally living with cardiovascular disease that has been affected by the pandemic,\" continued Benchouk.\nSanofi's mission has led them to create the Empower Hypertension Program, which aims to deliver awareness, prevention, and management to patient. The program provides enlisted patients with free coaching sessions led by nurse educators to arm them with information that tackles myths and facts about the disease, among others.\nSanofi has also partnered with Omron, a leading medical electronics company, to extend a 20% to 25% discounts to patients, encouraging them to procure the technology in order to monitor their blood pressure regularly.\nSanofi remains committed to its mission to promote hypertension management at the early stages and to inspire individuals to take control of their own health.", "pred_label": "__label__POS", "pred_score_pos": 0.9046976566314697} +{"content": "It pays to have enough spiritual resources\nA person without money thinks twice whether to take a bus or go walking. Someone with a lot does not even think twice about taking a taxi.\nSimilarly, when a situation arises that requires more understanding and tolerance than I have, I find myself out of my depth. If I have a stock of spiritual power and an understanding of the rules of life, I can deal with it without problems.\nUnhappiness is basically due to a lack of spiritual power. If I spend more money than I earn over a long period of time, I go bankrupt. If I spend more spiritual power than I replace daily, I become spiritually bankrupt.\nThe expression, ‘make hay while the sun shines’, refers to taking advantage of a favourable situation to prepare for when it is not. What I have to do is accumulate a stock of spiritual power through daily meditation practice.\nIf I meditate accurately for 15 to 20 minutes as my first act in the morning, then for two to three minutes from time to time during the day, and another 15 to 20 minutes at night, that stock should be sufficient to pass through most situations without tripping up.\nThis power tends to accumulate as I learn to think better. When larger obstacles appear, there is enough to get past them as well. Actually, obstacles appear along the way precisely to test my understanding and strength. Well understood, they always bring good lessons.\nKen O’Donnell, an author and international consultant on strategy and leadership, is the director of Brahma Kumaris’ services in South America.", "pred_label": "__label__POS", "pred_score_pos": 0.8723195195198059} +{"content": "A team led by Dr. Hee Jung Shin from the University of Ulsan in South Korea also found that CESM is comparable to breast MRI in this area.\n\"CESM is a promising modality that shows the potential to assess both morphologies, including microcalcifications and perfusion characteristics, at lower cost and faster acquisition,\" Shin and colleagues wrote.\nWider acceptance of screening mammography is also increasing the rate of DCIS detection, with researchers saying DCIS accounts for 20% of screen-detected breast cancers. However, they also said that between 18% and 39% of DCIS at core-needle biopsy are initially underestimated and are later recategorized as invasive cancers after definitive surgery.\nWhile it's rare that DCIS leads to nodal metastases, it may open the door for unnecessary biopsy, adding cost and inconvenience to patients.\nCESM has shown promise in recent years, with researchers highlighting that images can be obtained within the same session of breast positioning. This allows for direct comparison of enhanced locations on the contrast-enhanced recombined images to the microcalcifications on mammographic images.\nShin et al wanted to compare CESM with conventional mammography, breast ultrasound, and MRI when it comes to visualizing the extent of disease in patients with DCIS. They developed prediction models that utilized the four imaging methods.\nThey looked at data from 108 patients. A total of 113 lesions were analyzed, 50 being pure DCIS and 63 being underestimated DCIS.\nCEMS vs. other modalities for visualizing underestimated DCIS\nMammography\nBreast ultrasound\nBreast MRI\nCESM\nPure DCIS\n44%\n76%\n80%\n58%\nUnderestimated DCIS\n73%\n81%\n92%\n86%\nDetection rates for both pure and underestimated DCIS were found to be significantly different for mammography and CESM, but not for breast ultrasound and MRI.\nAdditionally, no significant difference was found in the ability to predict DCIS underestimation based on models that included disease extent on breast MRI or CESM.\nUnderestimated DCIS was more likely to present as calcified lesions on mammography and enhancing lesions on CESM. Fibroglandular tissue density on mammography and background parenchymal enhancement on CESM and breast MRI were not found to be significantly different between pure and underestimated DCIS.\nUnderestimated DCIS was also associated with higher nuclear grade (p = 0.001), the presence of comedonecrosis (p = 0.026), and suspected invasion (p = 0.004) on preoperative core biopsy.\nThe researchers said their preoperative prediction model may be useful for surgeons who want to estimate the benefit of performing upfront sentinel lymph node biopsy.\n\"A further study comparing CESM and breast MRI in the prediction of DCIS underestimation in a larger population would be useful in validating our prediction model,\" the study authors wrote.\nCopyright © 2021 AuntMinnie.com", "pred_label": "__label__POS", "pred_score_pos": 0.6311265230178833} +{"content": "Explorations of Genesis 2 intent on recovering God's ideal for the interrelationship between male and female often zoom in on the creation of Eve. We are better able to appreciate how the narrative supports that ideal when we engage the whole chapter.\nAs a change agent in the community, the body of Christ must come to an understanding of the biblical concept of the image of God. An understanding of humanity as the bearer of that image—regardless of any classification society or culture might impose—is intrinsic to the church’s engagement in seeking justice.\nCultures of hierarchy maintain authority by claiming ontological distinction. The power and dominance inherent in hierarchy, which directly conflict with ontological equality, perpetuates abuse. This session will examine the abuse that results from hierarchical human relationships and the biblical response to dominance.\nHow can we better serve and inform a growing diverse community with an egalitarian theology message that is clearly understood? What are better ways to create bridges of conversation that are not intrusive or divisive?", "pred_label": "__label__POS", "pred_score_pos": 0.9473326802253723} +{"content": "Abstract\nWe measured the magnetization of glacial and interglacial ice from the Vostok core to estimate the meteoric smoke concentration in Antarctic ice. We have found that, within the uncertainty of the method, the smoke concentration in ice in Antarctica is equivalent to that previously measured in Greenland ice. The virtually identical smoke concentrations despite the different ice accumulation rates in Greenland and Antarctica suggest that wet deposition is the main deposition mechanism for such ultra-small particles. Given the typical scavenging ratios for atmospheric aerosols, this would imply that previous estimates of accretion rate based on dry deposition are likely to be appreciably overestimated.\nAll Science Journal Classification (ASJC) codes Geophysics Earth and Planetary Sciences(all)", "pred_label": "__label__POS", "pred_score_pos": 0.521865725517273} +{"content": "Klippel-Trenaunay syndrome (KTS) is a rare complex vessel malformation syndrome characterized by venous varicosities, capillary malformations, and limb hypertrophy. However, extensive heterotopic ossification (HO) secondary to this syndrome is extremely rare. We report the case of a patient with previously undiagnosed KTS and extensive HO who presented with a femoral fracture secondary to a motor vehicle accident. Extensive ossification, which leads to compulsive contracture deformity and dysfunction of the leg, was distributed on the flexor muscle side, as revealed by the radiograph. The diagnosis was finally established by combining imaging and histological analysis with classical clinical symptoms. Amputation was performed at the fracture site proximal to the infected necrotic foci. Open management of the fracture was challenging owning to the pervasive ossification and tendency for excessive bleeding. Gene sequencing analysis showed homozygous mutation of FoxO1 gene. Definitive diagnosis of a combination of KTS and extensive HO requires detailed imaging analysis and pathologic evidence. Mutation of the FoxO1 gene, which regulates bone formation by resistance to oxidative stress in osteoblasts, is a potential factor in the microenvironment of malformed vessels caused by KTS.\nWanbo Zhu, Kai Xie, Jiazhao Yang, Li Li, Xujin Wang, Lei Xu, Shiyuan Fang.Diagnosis of Klippel-Trenaunay syndrome and extensive heterotopic ossification in a patient with a femoral fracture: a case report and literature review.\nBMC musculoskeletal disorders.2020 Apr 11;21(1):223\nPMID:\n32278353", "pred_label": "__label__POS", "pred_score_pos": 0.5241085886955261} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis issue brief explores Elementary and Secondary School Emergency Relief Funds (ESSER) and how these funds can support summer and afterschool programs. It reviews amount of ESSER funds for each state, what the funds can be used for, and how programs can access these funds through grants and contracts. It also includes examples of how CT, GA, NH, UT, and WV are using the funds.\nThis webinar explores best practices in providing older youth with supportive and meaningful employment experiences and paid internships. The panel includes representatives from National Youth Employment Coalition, Summer Youth Employment Program from Charlotte, NC, College to Congress, and Community Relations Manager from Bank of America.\nThe National Summer Learning Association has provided more than 40 webinars called the Voices of Summer Webinar Series. The webinars were held between spring 2019 and spring 2021. Presenters include national thought leaders, program providers offering promising practices, and researchers.\nThese webinars feature thought leaders, researchers, journalists, and award-winning program leaders who share practices and research. November 16, 2020 included providers sharing promising practices during the pandemic. November 17 included journalists to explore how the election might shape the landscape and leaders who talked about legislation needed right now.\nThe purpose of this playbook is to provide a long-term and sustainable framework for planning and executing evidence-based practices and partnerships for high-quality summer programs. It has a user-friendly design and includes sections on quality, safety, policies and funding, planning, and partnerships.\nThis webinar features Dr. Gil Noam from Partnerships in Education and Resilience (PEAR) who explores what the field might expect regarding an increase in mental health issues since the pandemic.\nThis virtual press conference brought together leading experts to explore summer solutions emerging in the pandemic. It begins with a review of the findings from the report by the National Academies of Sciences, Engineering, and Medicine on Shaping Summertime Experiences.\nThis video is a keynote speech delivered by Dr. Shawn Ginwright. He explores stories and research related to his healing-centered framework to overcome trauma by building hope through relational, restorative, and political strategies.\nThis issue brief is an interview with the evaluator of a STEM project with middle and high school tribal youth, working with tribal leaders and STEM professionals on a research project about salmon restoration. The evaluation shows how involving youth in an engaging and authentic research project built their STEM skills in a possible career path. There is a link to the full research report.", "pred_label": "__label__POS", "pred_score_pos": 0.8016537427902222} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis webinar series explores tools, tips, strategies, and resources for programs to deliver high-quality virtual programs. The first webinar is called Transforming from Virtual Bleh to Virtual Yeah! It offers a wealth of concrete tips to provide structured and consistent programming, increase student engagement, and battle virtual burnout, plus a review of online tools.\nThis issue brief provides background information about the structures of child care costs and revenues and shows how the pandemic has affected the financial picture of providers. The paper also describes implementation issues for allocating financial resources to stabilize child care programs and the workforce. This resource supports the COVID-19 response.\nThis report summarizes survey data collected in 2020, both before and during the pandemic; it is the fourth survey, preceded by findings from 2004, 2009, 2014.\nThis webinar series explores the importance of trauma-informed and healing-centered approaches in out-of-school time settings and the role they can play in helping youth manage and recover from trauma.\nThis policy brief summarizes findings from 22 focus groups with family child care (FCC) providers in CA, FL, MA, and WI during spring 2020. It reviews challenges that FCC providers faced as they provided care during the pandemic and the strengths they have that make them uniquely suited to respond to child care needs.\nThis report from National Summer Learning Association (NSLA) examines data from focus groups and interviews conducted with 21 leaders representing 15 national award-winning summer learning programs in September 2020 and data from a survey of 1,047 afterschool and summer providers conducted in partnership with Afterschool Alliance in July and August 2020.\nThis toolkit includes resources that will help build child care supply. It includes six steps: (1) assess and plan; (2) identify resources; (3) generate awareness; (4) develop strategies; (5) implement your plan; and (6) evaluate and implement. The concepts build on recognized strategic planning principles and include stories of success. This resource supports the COVID-19 response.\nThe Afterschool Alliance's webpage on COVID-19 offers a rich array of resources to help support Out-of-School Time (OST) system builders, administrators, and practitioners in navigating the challenges of the pandemic as they strive to effectively serve children, families, and providers.\nWith many school districts providing partial or full online learning, there is increased need for child care for working parents. This collection of online resources includes videos of providers, and identifies recommendations for new supports on funding, shared planning and decision-making, and technical supports. This resource supports the COVID-19 response.\nThis review of state plans for school reopening provides examples for ways states and districts can coordinate with afterschool programs to support their capacity, leverage resources, and support students and families.", "pred_label": "__label__POS", "pred_score_pos": 0.9554418325424194} +{"content": "Authors: LIXIN ZHANG, MEI GAO, SHENGXIU LI, ASHOK KUMAR ALVA, MUHAMMAD ASHRAF Abstract: In the present study, the role of potassium (K) in mitigating the adverse effects of drought stress (DS) on 2 maize (Zea mays L.) cultivars, 'Shaandan 9' (S_{9}; drought-tolerant) and 'Shaandan 911' (S_{911}; drought-sensitive), was assessed. K application increased dry matter (DM) across all growth stages and grain yield (GY) in both cultivars under DS, but not under control conditions. Drought-tolerant cultivar S_9 was superior to drought-sensitive cultivar S_{911} under DS in terms of DM and GY regardless of K addition. Additionally, K application increased relative water content, nitrate reductase activity, and concentrations of potassium ion, free proline, soluble protein, and endogenous glycine betaine in both cultivars. These positive effects due to K fertilization under DS were greater for S_{911} than for S_{9}. In contrast, the differences in the above parameters between K-treated plants and plants under control conditions were either nonsignificant or marginal. This study provides direct evidence of the beneficial physiological function of K fertilization in mitigating the adverse effects of DS by increased nitrate assimilation and osmotic regulation, but not due to its nutritive role.\nKeywords: Relative water content, nitrate reductase activity, osmotic solutes, Poaceae, potassium fertilizer Full Text: PDF", "pred_label": "__label__POS", "pred_score_pos": 0.9737040400505066} +{"content": "Knowledge collaboration and proximity - The spatial organization of biotech innovation projects\nForskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift\nAbstract\nThis article addresses the role of proximity for knowledge collaboration between dedicated biotechnology firms (DBFs) and related actors. Innovation projects managed by a selection of eight Swedish DBFs are analysed in detail and classified with regard to their specific knowledge characteristics. Based on this classification, explanations to the relative importance of functional and relational proximity to collaborators are sought. The findings indicate that knowledge collaboration in projects characterized by embodied knowledge are more sensitive to functional proximity than projects characterized by embrained and encoded knowledge. The findings also indicate that even though functional proximity is facilitative, global knowledge collaboration is indispensable for most DBFs. The convenience of local collaboration can never replace the extreme requirements of specialized knowledge, which forces them to seek collaborators on a global arena despite the impediments they face in these situations. Policy resources aimed at promoting bioregions are therefore better used to enhance local resources and to provide conditions for DBFs to link up with global sources of knowledge rather than to boost the formation of 'second best' local networks.\nDetaljer\nFörfattare Enheter & grupper Forskningsområden Ämnesklassifikation (UKÄ) – OBLIGATORISK Nyckelord\nOriginalspråk engelska Sidor (från-till) 115-131 Tidskrift European Urban and Regional Studies Volym 14 Utgåva nummer 2 Status Published - 2007 Publikationskategori Forskning Peer review utförd Ja", "pred_label": "__label__POS", "pred_score_pos": 0.625074028968811} +{"content": "The UK’s fresh produce imports from Spain rose 6% in value during the first 3 months of 2021 to reach €675 million. However, the UK’s departure from the EU has increased the administrative costs of managing shipments and documentary formalities. FEPEX reports that despite the increase in the value of exports, volumes decreased during the indicated period by 6%, to just under 462,000 tons.\nThe situation compounds an already challenging one for Spain, given the 3.5% fall in overall export volumes, as reported by the Customs and Excise Department in mid-May.", "pred_label": "__label__POS", "pred_score_pos": 0.997317910194397} +{"content": "Technology\nThird-Party Integrations\nREDO REDO REDO our Government customers often look to third-party integrations to support quick deployment, decreased costs, and minimal IT support. This is understandable due to the increased manageability of cloud technology implementation through common APIs. However, third-party integrations present multiple risks to strategic, regulatory, cybersecurity, and financial results. We help your agency proactively address, mitigate, and manage these risks.\nFirst, we ensure all third-party integrations have gone through the rigorous FedRAMP authorization program. FedRAMP allows government agencies to adopt cutting-edge cloud technology to improve customer experience while reducing procurement costs. However, third-party vendor utilization often means data is being transferred outside firewalls. By walking you through security and risk assessments, we take the guesswork out of FedRAMP requirements and ensure program compliance.\nWe develop strategies to manage communications, operations, change management, and integration rollback plans. We facilitate collaboration among all cross-functional teams to capture executive guardrails, success criteria, business requirements, and milestones, while always keeping customer experience at the forefront.\nTactical Deliverable Examples:", "pred_label": "__label__POS", "pred_score_pos": 0.9998054504394531} +{"content": "Global nickel mine production is expected to grow by 6.8% to reach 2,427.4 thousand tonnes (kt) in 2021, after registering an estimated 4.2% decline to 2,272kt in 2020, owing to the Covid-19 related lockdowns and restrictions. Output from Indonesia (+16.3%), the Philippines (+5.1%) and Brazil (+24%) will be significant contributors to the overall growth this year. In contrast, production is expected to decline in Russia (-13.8%) and South Africa (-15.8%).\nCombined production from Indonesia, the Philippines and Brazil is expected to increase from a collective 1,160kt in 2020 to 1,316.8kt in 2021 – an increase of 13.5%. The increase in production will be supported by the expansion of Indonesia’s nickel industry, the resumption of production at various mines in the Philippines and the ramp-up at the Santa Rita mine in Brazil, which was previously halted in 2015.\nOverall, Indonesia and the Philippines will remain as the largest sources of nickel globally. Together with Russia, New Caledonia and Australia, these five countries account for almost three-quarters of the global total. Looking ahead, nickel production over the forecast period is expected to grow at a compound annual growth rate (CAGR) of 3%, to reach 2,730.6kt in 2025. Indonesia, Russia, Canada and the Philippines will be the key contributors to this growth. Combined production in these countries is expected to increase from a forecasted 1,607kt in 2021 to 1,818.4kt in 2025.\nProjects with potential to commence operations during the forecast period include the Araguaia Nickel project in Brazil, which is wholly owned by Horizonte Minerals, and is currently awaiting a final investment decision (FID). The $402.1m project will have an annual nickel production capacity of 14.5kt and is expected to commence operations in 2022. During early 2021, the project’s infrastructure, including the award of construction licences for the transmission line and the water pipeline, was approved by the company. Tenders for the supply of key equipment and services have been completed for approximately $230m.\nThe Aquila Nickel project in Indonesia, which is wholly owned by Solway Investment Group, has obtained its regulatory approvals and permissions. The $57m project will have an annual nickel production capacity of 16.6kt and is expected to commence operations in 2023.", "pred_label": "__label__POS", "pred_score_pos": 0.9884178638458252} +{"content": "If you're choosing new gutters for a new roof, you're likely to get caught in between seamless and seamed gutter options. But which is the best gutter system for your modern home? Ideally, you should select gutters that offer excellent functionality, stunning aesthetics, and low maintenance.\nWhen you opt for seamless gutters, you don't have to spend on sealants, fasteners, and clips. This type of gutter guarantees minimum repairs since there are no weak points or vulnerable seams. You should work with a seamless gutter installer to help you design a system that performs optimally.\nHere are reasons why you need seamless gutters in your new home.\nSeamless Gutters Offer Durability\nIf you choose seamless gutters, you can rest knowing that they'll secure your walls from water damage for the long term. These gutters won't clog easily, and they won't fail like other gutters with endless joints. For instance, if you select aluminum gutters, you'll enjoy minimum maintenance and the aluminum is weather-resistant. You'll enjoy hardy gutters that don't require replacing until decades later.\nThey're Custom Designed\nDid you know that seamless gutters present endless customization options for your property? These gutters fit your property's specifications, and you don't need to refit them. This means they'll perform outstandingly to keep water from leaking off the eaves. Given the range of shades, you can engage a roofing professional to assist you in finding ideal gutter colors that complement your home's decor and style.\nCustomized seamless gutters present proper workmanship during installation. They offer a highly functional system and an impressive look. If you're a minimalist, seamless gutter provides the simplicity you prefer on your fascia board.\nThey Prevent Leaks\nGutters that safeguard your foundation from water seepage save you the money you'd have spent to repair a water-damaged basement or foundation. Seamless gutters rank as the perfect option if you want to lead runoff farther from the foundation. Since they don't have joints, they won't trap debris like seamed gutters. An experienced gutter installer will mount your gutters the right way to eliminate possible leaks.\nSeamless Gutters Are Low Maintenance\nDirt and debris are the number one enemy to your gutter system. When they sit inside your seamless gutter trough, they won't accumulate, especially at the joints. Runoff clears the leaves and debris, and you don't have to call roof maintenance services all the time. You should get skilled roofers to install seamless gutters professionally to save money.\nWhen you want something built, who do you turn to? Okay, maybe you answered that question with a particular person's name, and that's an acceptable answer. But the answer we were really looking for was \"construction contractors.\" This profession is full of people who can build this and that, and who can customize the things they build to meet your unique needs. Working with a construction team is like working with a bunch of people who just want to make you happy. We love that aspect of the industry, and it's something we plan on focusing on more as we write this blog.", "pred_label": "__label__POS", "pred_score_pos": 0.991391122341156} +{"content": "BWIC Volumes\nSeptember BWIC volumes were muted, with posted BWICs totaling just over $2.0 Bn and traded at $1.8 Bn. Posted and traded volumes continue in close tandem, with over 90% of posted BWICs trading during September. This trend is a good indicator of demand and a positive for the CLO market liquidity.\nTRACE* Volumes\nReported CLO trading volumes jumped to $14 Bn in September, a sharp $5.5 Bn increase over August. The increase was attributed to the non-IG volume, which was the largest YTD.\nBWICs as % of TRACE\n$1 Bn daily TRACE volume is a rare occurrence. An average month has 1 to 3 days with over $1 Bn in trades. September 22 saw over $6 Bn in non-IG trades reported to TRACE- a sharp outlier. Due to such volume, only 6% of non-IG securities traded via BWICs in August, while IG bonds returned to a longer-term average of 29% in September.\nBWIC Volumes By Rating\nOnly half of the typical AAA volume traded; $550 million of AAA securities were sold via BWIC compared to the trailing 12-month average of $1.1 Bn. Similar drops in volumes were seen across the capital stack, with $220 million of AAs trading on BWIC. CLO equity, on the other hand, was slightly higher than its trailing 12-month average with $240 million trading via BWICs.\nDNT Rates\nWe see low DNT rates across investment-grade securities including a 0% DNT rate for AAAs, AAs and As. Low DNT rates are indicative of strong market demand and sellers being happy with the prices they’re receiving. Lower in the cap stack, the positive trend has returned in September and we observed lower than average DNT rates for BBB, BB and equity.\nDealer’s Inventory\nDealers purchased over $6 Bn from clients in September 2021, a sharp increase that seems to be driven by a single trade on September 22 in non-IG-rated securities.\nPrices** Across the Stack\nFrom August to September we saw price increases across the stack. The bottom part of the capital structure saw bigger improvements where BB-rated bonds were up 3 points.\nCLO Equity IRRs\nThe last few months have seen an increased volume of CLO equity traded via BWIC. The average September equity IRR% based on the 18 trades with public color was 12.6% according to the standard secondary market pricing assumptions.\n*TRACE reports all CLO trades involving FINRA members.\n**Prices are based on trades that provided color and are likely to underestimate actual traded levels.", "pred_label": "__label__POS", "pred_score_pos": 0.8190856575965881} +{"content": "Laser treatment shows potential for reducing industrial chemical processing for vehicles\nLong-lasting protection from corrosion is essential for materials used for vehicles and aircraft to ensure structural integrity amid extreme operating conditions. Two chemical pre-treatment processes are widely used in industrial settings to prepare for coating adhesion and protect aluminum alloy surfaces against corrosion. While highly regulated, both processes use large quantities of hazardous compounds with known environmental and health risks.\nA multidisciplinary team of scientists at the Department of Energy's Oak Ridge National Laboratory has applied a laser-interference structuring, or LIS, technique that makes significant strides toward eliminating the need for these hazardous chemicals. The novel application of the LIS method answers a call from the U.S. Department of Defense for research projects that explore nonchemical alternatives for corrosion protection in military vehicles and aircraft systems.\nChromate conversion coating, or CCC, uses hexavalent chromium, a known carcinogen, to inhibit corrosion. Sulfuric acid anodizing, SAA, uses sulfuric acid, which can severely irritate skin and eyes, and when inhaled, can lead to permanent lung damage. Millions of gallons of used chemical solutions are disposed of annually as hazardous waste.\nThe military operates more than 12,000 aircraft, 10,000 tanks, hundreds of ships and a multitude of other vehicles and weapons systems. DoD owns and operates hundreds of industrial facilities that manufacture and repair these vehicles and equipment, spending more than $20 billion in corrosion protection annually. The agency's Strategic Environmental Research and Development Program, or SERDP, planned and executed with the Department of Energy and the Environmental Protection Agency, is \"focused on developing alternative technologies to eliminate materials and processes that are of environmental concern,\" said Robin Nissan, program manager of SERDP and its sister program, the Environmental Security Technology Certification Program.\n\"Our defense systems require repair and refurbishment,\" he said. \"Our programs are investing in the development of alternative processes that can ensure robust performance, sustainable practices and eliminate environmental risk.\"\nIn three successive publications, ORNL materials scientist Adrian Sabau and a team of chemists and manufacturing scientists described, demonstrated and analyzed an LIS technique and compared its performance to the traditional solvent-intensive methods. Co-authors on the research included ORNL's Jiheon Jun, Mike Stephens, Dana McClurg, Harry Meyer III, Donovan Leonard and Jian Chen.\nSabau—who specializes in materials processing such as metal casting and solidification—and his team had recently completed a project using LIS for bonding in automotive applications. When he read DoD's call for research on nonsolvent surface preparation, Sabau recognized that a similar technique could be effective for coating adhesion as well.\nIn their experiments, they treated aluminum alloy sheets by splitting the primary beam of a pulsed nanosecond laser into two beams and focusing them on the same spot on the specimen surface. This process roughened the surface with periodic structures, changed the surface chemistry and sub-surface microstructure.\n\"In laser processing, you're impacting lots of energy on the top surface, and we need to understand what's happening to the substrate. Is it damaged? Does it crack? Are there any microstructure effects that are not beneficial to corrosion protection?\" Sabau said.\nMeyer, a physical chemist, and Leonard, a microscopist, contributed to the characterization work outlined in\nOptics and Laser Technology. Meyer conducted surface chemical analysis using X-ray photoelectron spectroscopy, or XPS.\n\"XPS is a material characterization technique that can determine what elements are on the surface—the top 5 to 8 nanometers—of solid materials,\" Meyer said. \"Before laser processing, XPS was used to determine the chemical composition of the as-received aluminum alloy sheets, which showed high amounts of carbon. XPS was used again to determine if the laser processing cleaned the surface. The results showed a significant reduction of the carbon and was one of our key findings. XPS, along with electron microscopy results, helped us to understand how the native oxide was altered through laser processing.\"\nSabau added, \"In looking at subsurface characterization, we found a beneficial aspect that we bumped into by accident. In the top layer, we saw the dissolution of copper-rich precipitates, where corrosion can initiate.\"\nAfter an aluminum alloy sheet is cleaned, often the surface energy prohibits the coating from sticking properly, a known issue in industrial surface coatings. The team's next publication, for the\nInternational Journal of Adhesion and Adhesives, looked at coating adhesion and found that the LIS method provided adhesion as well as the industry-standard and solvent-intensive CCC and SAA techniques. A patent for coating adhesion was awarded in 2021 based on this LIS technique.\nFor the adhesion study, McClurg conducted profilometry on the materials, a technique that maps surface contours and provides roughness measurements.\nThe third paper, published in\nCorrosion: The Journal of Science and Engineering, outlined the final tests that Sabau's team conducted with an epoxy primer used by the U.S. military for airplane wings and bodies.\nTechnician Mike Stephens completed the delicate and time-sensitive task of applying spray coatings of primers and topcoats to exacting DoD specifications on alloy sheets that had been prepared with different treatments. He then exposed the samples to 2,000 hours of salt spray to examine corrosion resistance at multiple periods. Jun led the corrosion testing, investigating how the LIS-prepared surfaces compared to conventionally prepared alloy substrates, both with and without primer and a topcoat.\n\"The laser interference-treated substrate exhibited higher corrosion resistance,\" said Jun, who attributed the result to copper-rich precipitates dissolving. However, on the samples coated with primer or primer and topcoat, LIS did not perform as well as the chemical solvent techniques, with some samples showing blisters within 96 hours of salt spray exposure. However, those blisters were small and remained stable through hundreds of hours of exposure.\nThe team tested a second set of samples that were simply wiped down with acetone prior to the application of primer, resulting in very little corrosion, and the formation of blisters was delayed by hundreds of hours.\nJun said further investigation to optimize LIS would be worthwhile.\n\"Our research approach, combining lab-scale electrochemical measurements and industrially adopted ASTM [American Society for Testing Materials] salt spray testing, was very successful and aided in-depth understanding of the effects of laser interference treatment,\" he said.\n\"For a process that was conducted at ambient temperature without solvents, most of the samples performed extremely well,\" Sabau said. \"This technique is a huge step in the right direction towards nonchemical intensive surface preparation for coatings.\"\nExplore further\nMore information:Adrian S. Sabau et al, Laser-interference pulse number dependence of surface chemistry and sub-surface microstructure of AA2024-T3 alloy, Optics & Laser Technology(2020). DOI: 10.1016/j.optlastec.2020.106457\nAdrian S. Sabau et al, Coating adhesion of a chromate-containing epoxy primer on Al2024-T3 surface processed by laser-interference,\nInternational Journal of Adhesion and Adhesives (2020). DOI: 10.1016/j.ijadhadh.2020.102641\nJiheon Jun et al, Corrosion Behavior of Laser-Interference Structured AA2024 Coated with a Chromate-Containing Epoxy Primer,\nCorrosion (2021). DOI: 10.5006/3717 Citation: Laser treatment shows potential for reducing industrial chemical processing for vehicles (2021, September 23) retrieved 16 October 2021 from https://phys.org/news/2021-09-laser-treatment-potential-industrial-chemical.html", "pred_label": "__label__POS", "pred_score_pos": 0.5202019214630127} +{"content": "Going through a divorce can certainly throw one or both parties off balance. However, if there is a power struggle or imbalance in the marriage, this can make the divorce even more challenging. If you live in Illinois, here are some crucial things you should know about power imbalances and how you can handle them in the best possible way as you prepare to end your marriage.\nWhat is a power imbalance?\nMarriage should ideally be a relationship between two equals. Even though each spouse is different and may carry out different duties in the household and the relationship, they should have equal value and worth. A healthy marriage requires both spouses to discuss decisions and come to a conclusion they are both satisfied with, or to come to a compromise that works for both parties. However, if there is a power imbalance in the relationship, one spouse has control in certain matters. The spouse who is more powerful will often force their way of doing things on the other spouse, and this often leads to divorce.\nDivorce and power imbalances\nEven if one or both spouses don’t exhibit controlling behavior in a marriage, they may do so during the divorce. For instance, if one spouse was making all or the majority of the money in the marriage, this spouse may try to take the retirement funds, marital home, and family cars in the divorce.\nA spouse may also use their relationship with the children to exercise control over the other spouse. If the children are more loyal to or spend more time with one parent, the parent who is ‘more loved’ will often demand custody of the children in the divorce. Spouses can also try to be controlling in a divorce from an emotional standpoint. This occurs when one spouse is no longer emotionally invested in the marriage and the other is still holding out hope that the relationship can work.", "pred_label": "__label__POS", "pred_score_pos": 0.7701836228370667} +{"content": "►▼Show Figures\nHeart rate variability (HRV) is a simple, non-invasive, real-time analyzable, and highly reproducible measurement that captures incidences for assessing a person’s health and physical condition. Public security jobs are characterized by major exposure to risk factors known to influence the cardiovascular response to stimuli, e.g., night shifts, highly physically demanding activity, and acute stress activity. This study aimed to evaluate the HRV parameters in a population of 112 male personnel of the special forces and public order of the Carabinieri, aged 25–59, when engaged in several duty tasks, such as paratroopers, night shift police station officers, night shift patrol, dynamic precision shooting evaluative team, dynamic precision shooting non-evaluative team, and office clerks (used as control group). During the specific task of each participant, the HRV parameters were collected with wearable devices and processed. The HRV parameters in the time and frequency domains collected were average heart rate, standard deviation of all normal RR intervals, root mean square of successive differences in adjacent normal-to-normal (NN) intervals, very-low-frequency power, low-frequency power, high-frequency power, stress index, parasympathetic nervous system activity index, and sympathetic nervous system activity index. Parametric tests for independent series to compare the HRV parameters by subgroups within the study subjects were used. A multivariate linear regression analysis was conducted to evaluate the association between the HRV parameters and some personal and organizational factors. The comparison between different subgroups showed that activities with a high demand for concentration and precision, as is the case with paratroopers and dynamic precision shooters, differ significantly from activities that can be defined as routine, such as office work. Other activities, such as patrolling or remote management from operations centers, although including critical elements, did not deviate significantly from the control group. The study of HRV parameters is therefore a useful tool for occupational physicians, both for addressing work suitability assessments and for better targeting health promotion campaigns, to be considered as being aimed at monitoring the subject’s physiological parameters, and not at the diagnosis of any pathological condition, which should always be carried out by the medical specialist.View Full-Text\nThis is an open access article distributed under the Creative Commons Attribution License\nwhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited", "pred_label": "__label__POS", "pred_score_pos": 0.5069981217384338} +{"content": "Govt. sets Ethanol production & EV sales target Govt. of India aims to achieve electric car sales penetration of 30% by 2030.\nMr. Nitin Gadkari, the minister of road transport and highways, has announced new targets for ethanol production and EV sales to reduce pollution levels in the country.\nThe minister stated that flex-fuel vehicles would play a crucial role in decarbonising the transport sector. The government is aiming at an Rs. 2 lakh crore ethanol economy from its present size of Rs. 20,000 crore. The development of an extensive ethanol industry would mean new markets for the country’s biomass and agriculture sector.\nThe use of bio-CNG and green hydrogen is also expected to reduce air pollution. The government aims to set up 10,000 CNG stations in the country.\nFurther, the government intends to achieve electric vehicle sales penetration of 30% for private cars, 70% for commercial vehicles, 40% for buses, and 80% for 2-wheelers and 3-wheelers by 2030.\nSource: Read Full Article", "pred_label": "__label__POS", "pred_score_pos": 0.8978199362754822} +{"content": "The retail mortgage lender Guaranteed Rate is creating a Bilingual Diversity Processing Team to lead their new Language Access Program (LAP). LAP aims to connect more meaningfully with Spanish-speaking customers and guide them throughout the mortgage process. And as part of this initiative, industry veteran Arlyn J. Kalinski has been hired as the compliance director for the Limited English Proficiency (LEP) Program.\nIn this role, Kalinski will oversee key aspects of LAP. This includes training and recruiting new LAP specialists as well as reaching out to the community to educate members on financial literacy. And within Guaranteed Rate, Kalinski will oversee internal programs to provide further opportunities those employees who are invested in supporting limited English-speaking communities.\nLAP was launched this October, in time for National Hispanic Heritage Month and will begin with a primary focus on Spanish speakers — particularly as the demographic of Hispanic homebuyers expands. The Urban Institute predicts that over the next 20 years, 70% of new homebuyers will be Latino. The National Association of Hispanic Real Estate Professionals has also released data which illustrates the fast-growing pace of investment property ownership among the Latino community.\nThese trends indicate an imperative necessity to communicate effectively with Spanish-speaking clients. Speaking on the topic, Kalinski said, “Hispanic homeownership is at a tipping point. This is an opportunity to meet the moment by addressing the homeownership needs of this expanding population and provide additional resources, education and outreach to diverse communities throughout the country.” Kalinski herself is a native of Puerto Rico.\n“I’m excited to join Guaranteed Rate and help lead efforts to create greater access to affordable mortgages while reducing inherent challenges often faced by underserved communities,” she added.\nGuaranteed Rate’s executive director of diverse segments, Camilo Escalante, also looks forward to Kalinski’s possibilities at the company. “Adding Arlyn to drive our efforts ensures that we’re on the forefront of the industry with our commitment to LEP consumers,” he said. “She’s the key piece to helping us win in this marketplace and set a model for the entire industry to follow.”", "pred_label": "__label__POS", "pred_score_pos": 0.9516763687133789} +{"content": "Feminist media scholars have historically centered gender and identity on thebody and visual texts, with the voice exercised as metaphor - immaterial or interpretedsolely as the words spoken. Representative of agency, the voice gets defined as what isbeing said rather than how one is saying it. My thesis addresses this gap through an earorientedanalysis of women’s voice within the Canadian radio and podcasting industry.Centred on the experiences of individual women in Toronto’s broadcast soundscape, Ibring a feminist phenomenological approach to my work to explore the intersection ofvoice as both material sound -an extension of the body and thus individual identities- andthe weight of the women’s voice as politically and historically coded. I aim to expand mywork beyond the individual experiences of the women within the broadcast industry andinto the broader discourse surrounding gendered representation for the future of ourCanadian media soundscape.", "pred_label": "__label__POS", "pred_score_pos": 0.9242881536483765} +{"content": "Author(s):Muhammad Zubair Khan | Amanullah Khan Miankhel | Allah Nawaz Journal:Acta Universitatis Danubius : Communicatio\nISSN 1844-7562\nVolume:6; Issue:2; Start page:143; Date:2012;\nOriginal page\nKeywords:ICTs | Digital Divide | Economic divide | Integrative technologies | Ris ing affordability ABSTRACTA consensus is swiftly emerging regarding the democratizing impacts of moderncommunication technologies. However, the major challenge in this perspective comes from ‘digitaldivide’ which refers to ‘haves’ and ‘have not’ of the modern communication technologies and accessto information. This divide, primarily stems from the existing socioeconomic divides. However, inperspective of existing scholarly research and quantitative data on the issue, it is argued that digitaldivide is diminishing gradually. The advancements in technology particularly the integrative featuresof modern technology along with increasing affordability is denting the digital divide. The ebbingaway of digital divide has various implications for individual, civil society and state.This articleelaborates this issue at length by juxtaposing the findings from the existing research and presents acompact schematic model for better comprehension of the issue.", "pred_label": "__label__POS", "pred_score_pos": 0.9998514652252197} +{"content": "Improving Outcomes by Modifying Approaches for Those with Fetal Alcohol Spectrum Disorders (FASD) Dan Dubovsky, MSW\nThis training builds on the first FASD training provided. Due to the brain damage caused by prenatal alcohol exposure, which spans the intellectual spectrum, evidence-based practices that rely on verbal interactions and reward and consequence approaches such as point, level, and privilege systems, are often not successful with them and set them up to fail. As a result, interventions for them in mental health and substance use treatment, vocational services, child welfare, education, and corrections are often ineffective.\nThis training discusses the importance of developing a true strengths-based approach to working with individuals with an FASD. Strategies for modifying approaches to improve outcomes for the individual, family, and service providers are highlighted.\nLearning Objectives: Describe a positive focused system of care. List five strengths often seen in individuals with an FASD. List four strategies to improve outcomes for individuals with an FASD. Webinar Recording:\nAfter viewing the webinar above, you have the option to download a Certificate of Viewing by Completing a brief evaluation and attesting that you viewed the webinar in its entirety. However, this is not a Certificate of Attendance for the webinar when it was live broadcasted. Additionally, viewing the webinar through the website does not permit applying for or issuing Continuing Education Credits.\nPlease\nto start the evaluation and download your Certificate of Viewing. Click Here PDF Version of PowerPoint", "pred_label": "__label__POS", "pred_score_pos": 0.9631281495094299} +{"content": "This rule, which has been in effect for decades under the federal Clean Air Act, measures and regulates limits for six pollutants often attributed with acid rain, smog, air pollution, and human health hazards.\nCopy and paste this URL into your WordPress site to embed\nCopy and paste this code into your site to embed", "pred_label": "__label__POS", "pred_score_pos": 0.9226399064064026} +{"content": "Translation by Yehoshua Siskin\nI was listening to the news yesterday and it occurred to me that what we need most at this moment is trust. We need to trust that if a rabbi is beaten up on Yafo Street or a youth is slapped on the light rail, the police will respond quickly to such incidents and prevent them from happening again. We need to trust that if a soldier in the IDF is wounded, whether physically or psychologically, he will receive proper rehabilitation. We need to trust that when we order dessert in a meat restaurant, the dessert served will not be dairy. We need politicians to trust each other, while it seems that they are insincere and are just trying to fool each other. And we need politicians and the people to trust each other too.\nIn the synagogue on Shabbat, we will read parasha Kedoshim: \"You shall be holy,\" the Torah declares. Yet this exhortation is not about dry or abstract laws, but is a call to being truly spiritual, where we care deeply for one another. Being holy concerns our relationships and how we create a positive atmosphere of mutual respect, which is only possible where people fully trust each other.\n\"You shall rise before the aged, and respect the elderly.\nYou shall not steal; you shall not deal deceitfully or falsely with one another.\nYou shall not defraud your fellow. You shall not commit robbery.\nYou shall not withhold the day laborer's wages overnight.\nYou shall not curse the deaf, nor place a stumbling block before the blind.\nYou shall not render an unjust judgment. You shall neither favor the poor nor show deference to the rich. You shall judge your fellow fairly.\nYou shall not speak gossip among your people.\nYou shall not stand idly by your brother's blood.\nYou shall not hate your brother in your heart. You shall love your neighbor as yourself.\"\nThe above constitutes a social policy of trust and, if implemented here, would bring glory to the State of Israel.", "pred_label": "__label__POS", "pred_score_pos": 0.9771513342857361} +{"content": "Given the convenience and effectiveness it offers, spray tan is emerging as a popular choice among tanning enthusiasts. It can help achieve a smooth and even tan quickly without having to expose yourself to sunlight or radiation.\nHowever, a majority of people have concerns about sweating after spray tan sessions. Are you wondering if you can sweat after a spray tan? No, because sweating can adversely affect the spray tan solution leading to uneven results.\nRead on to find out how sweating interferes with your spray tan and how you can minimize sweating.\nIs It Okay to Sweat After Tanning?\nUnfortunately, sweating after a spray tan is not an ideal situation. The spray tan is immensely vulnerable, especially within the first few hours.\nWhen you head for your spray tan appointment, the technician will spray a solution all over your skin. It contains DHA and bronzer that helps you achieve a darker skin tone.\nIf you expose yourself to heat or exercise, you can start sweating. When the solution comes in contact with moisture, it can lead to a streaky, patchy, and uneven tan. You might even have to go for another spray tan session to cover it up. Each spray tan appointment costs from $18-$100, making it an expensive mistake to make.\nCan you sweat with a spray tan? No, since it can affect your tan, and sometimes it might even turn green, giving you undesirable results.\nHow Can You Prevent Sweating After Spray Tanning?\nThe most significant risk to your tan can be your own sweat and body moisture. Wondering how long after spray tan can I sweat? Since the spray tan solution can take anywhere from 4 to 5 hours to settle in, even minor exposure to sweat or moisture can lead to an uneven tan.\nIf you’re wondering how to avoid that, here are a few tips to prevent sweating:\nGo For Tanning Late Afternoon:\nYou sweat more in the morning and afternoon when the sun is bright. It is wise to schedule your tanning appointment in the late afternoon or evening, especially in summers. This might help reduce the chances of sweating and ensure you get an even tan.\nAvoid Sun Exposure:\nAnother basic yet essential tip is to stay cool and avoid getting exposed to sunlight. The sun can increase your body temperature, leading to sweating.\nIf you have to step out in the sun, make sure you use a broad-spectrum sunscreen that is waterproof to avoid sweating and prevent damage to your spray tan.\nSkip Exercising:\nCan I work out after a spray tan? Exercising is synonymous with sweating. If you have gone for a spray tan appointment, you must give it at least 3-4 hours to settle or in an ideal case 24 hours. You can continue your exercise regime after a day. Avoid swimming in water that contains chlorine to protect your tan.\nChoose a Salon With Ventilation:\nIt is imperative to choose a suitable tanning salon. While picking a salon for your next tanning appointment, make sure it has a cooling system, ceiling fans, or natural ventilation to allow your tan to dry properly. It will prevent sweating even in humid weather conditions.\nApply Talcum Powder:\nAnother trick that helps prevent sweating is using talcum powder. You can ask your tanning technician to apply talcum powder all over your body using a body brush. It will not only allow easy movement of your body parts but also prevents moisture or sweat from ruining your tan.\nWe Recommend: Imperial Leather Talcum Powder Go for Light Tan:\nIf you opt for a darker tan, there is an increased chance of you ending up with a patchy tan. The ones who have an active lifestyle and tend to sweat a lot must opt for a lighter tan. With a lighter tan, even if you end up with patches or streaks, it will be easier to hide and less noticeable.\nIf you’re not satisfied, you can go in the next day for another spray tan appointment; however, you must not spray tan too often.\nLet It Dry Completely:\nA crucial thing to identify is how long to let a spray tan dry. Once the technician has applied the tanning solution, wait for a little while (10-15 minutes) for it to dry before you get dressed. It will ensure the solution gets enough time to set and doesn’t crack.\nRelated Questions: Does Sweating Ruin a Spray Tan?\nYes, sweating or exposure to moisture right after the appointment can ruin a spray tan. Here, it is natural to wonder how long for a spray tan to set. Well, the tanning solution can take 3-4 hours to settle, and if you sweat during that time, it may lead to steaks, patches, and uneven tan.\nHow Long Until You Can Sweat After a Spray Tan?\nThe time your tan needs to settle can depend on a variety of factors, ranging from the tan shade, your skin type, and tanner used. However, it is ideal to wait for around 8 hours before you can sweat after a spray tan.\nWhat Not to Do After Spray Tan?\nAfter your spray tan appointment, you must not take a shower too soon. Washing off the tan early will affect the results, and you might end up with an uneven tan. Wait for 6-8 hours before taking a shower after spray tanning.\nYou must also avoid exfoliating or shaving your skin post tan as it will strip away the color though before a tan exfoliating the skin is recommended. Wear loose clothes and moisturize the skin for a smooth and even tan.", "pred_label": "__label__POS", "pred_score_pos": 0.7566316723823547} +{"content": "As a travel writer and sustainable tourism consultant, I work closely with travel businesses, tourism boards, non-profits, governments and sustainability-minded brands to help achieve their environmental and social impact goals.\nI believe in the potential of tourism as a tool for sustainable development, environmental conservation and meaningful cultural exchange. I’ve spent the past decade developing digital storytelling techniques, writing about environmentally and socially conscious travel experiences (without necessarily using the word ‘sustainable’), and creating market linkages for travel enterprises from Guatemala to Goa.\nDuring the pandemic, I co-founded Voices of Rural India, a not-for-profit initiative that works with rural communities across India to build alternate livelihoods through digital storytelling.\nInterest areas Community-owned tourism (CBT) Sustainable tourism solutions in mountain ecosystems Eco-luxury tourism development Regenerative travel\nIf you’re a tourism or sustainability professional, I’d love to connect with you on Linkedin.\nTo discuss a project, please reach out to me at shivyanath@gmail.com.", "pred_label": "__label__POS", "pred_score_pos": 0.6901881694793701} +{"content": "This book contributes an analysis of UK-based non-governmental organisations engaged in transnational lesbian, gay, bisexual, and trans (LGBT) activism, within a broader recognition of the complexities that British colonial legacies perpetuate in contemporary international relations.\nFrom this analysis, the book suggests that greater engagement with intersectional and decolonial approaches to transnational activism would allow for a more transformative solidarity that challenges the broader impacts of coloniality on LGBT people's lives globally.\nCase studies are used to explore UK actors' participation in the complexities of contemporary transnational LGBT activism, including activist responses to developments in Brunei between 2014 and 2019, and the use of LGBT aid conditionality by Western governments.\nActivist engagements with legacies of British colonialism are also explored, including a focus on 'sodomy laws' and the Commonwealth, as well as the challenges faced by LGBT people seeking asylum in the UK.\nAll items are delivered directly to your door in plain discreet packaging.\nFor UK deliveries we use Royal Mail 48 Hour Service. Quantities of stock are displayed on the product page. Items that are in stock will normally be dispatched within\n1-2 working days, with the exception of bank holidays. Some items may be shipped directly from the distributor.\nInternational delivery times may vary depending on that countries delivery service. Please allow 14 days before contacting us to chase your delivery.\nInternational orders may be subject to customs and duty charges at the recipients end.\nFor items displayed as\nBackorder Now, these will be dispatched once they return to stock. We will keep you updated on their progress.", "pred_label": "__label__POS", "pred_score_pos": 0.9804906845092773} +{"content": "Due to disease complexity, cancer research is a multidisciplinary field that spans basic, translational, and clinical research. Advancements depend on an increased understanding of the tumor cell environment and cancer biological, etiologic, clinical, and genetic heterogeneity. Insights into the causes and mechanisms of cancer development and progression have yielded new methods for cancer prevention, detection, and treatment. Improved detection methods have increased the rate of early detection and contributed to decreased cancer mortality for several cancer types, but a significant gap remains in asymptomatic and population-based screening methods.", "pred_label": "__label__POS", "pred_score_pos": 0.9633966684341431} +{"content": "The ASP Urban Interlock System has been designed for applications where stone or tile finishes are to be applied. The panels specially designed interlock edge profile ensures panels remain locked together, eliminating movement.\nThe Urban Interlock System has been scientifically designed to disseminate load transference through the system to ensure there are zero stress rises and zero deflection within the system.\nDeflection and stress rises were a great problem for access floors in the 1970’s, 80’s and 90’s due to the basic design and lack of understanding of building movement and design.\nASP has designed a proprietary interlock system that is able to take great loads both static and dynamic. This has provided the perfect solution imitating a secondary slab effect that ensures tiles and stone finishes do not crack.\nThe Interlock system provides an interlocked design, which ensures no movement and so eliminates the need for substrates. This elimination of substrates means the Interlock is a cost and time efficient design solution.\nThe Urban Interlock Panel is a composition panel with its main core ingredients of gypsum and fibre. A galvanized steel base plate is adhered to the core, creating a strong durable panel suitable for various environments.\nThe use of the Urban Interlock system provides the following benefits:\nOutstanding static and live load performance\nPrevents cracking in tiled and stone areas\nEliminates movement\nNon-combustible\nMoisture resistant\nEase of maintenance and serviceability with interchangeable panels\nGreat durability and lifespan contributing to a significant reduction in life cycle costs\nHigh recycled content\nLCA & EPD\nCreates a quiet and comfortable underfoot solution", "pred_label": "__label__POS", "pred_score_pos": 0.5229440331459045} +{"content": "- 40 % fewer calories than sugar\n- Low glycaemic index of approx. 10 - 100% natural birch sugar from Finland - no genetic engineering: produced from hardwoods and not from corn starch - Positive influence on dental health - Can be used 1:1 like sugar\nBirch sugar (xylitol) is a natural sugar substitute. It has the same sweetening power and texture as granulated sugar, and has 40% fewer calories. Xylitol is tooth-friendly and has a low glycemic index (approx. 10). Our birch sugar is extracted from wood, not from corn and without genetic engineering! Trees are not felled for the production of xylitol. Xylitol is also suitable during pregnancy and for children from the age of two. Xylitol is not suitable for babies and animals!\nIngredients: Xylitol (E967) Origin: Finland May have a laxative effect if consumed in excess.", "pred_label": "__label__POS", "pred_score_pos": 0.9348036050796509} +{"content": "The Syphilis Rapid Test Device (Serum/Plasma) is a rapid visual immunoassay for the qualitative, presumptive detection of IgM and IgG antibodies to Treponema Pallidum (TP) in human Whole Blood, serum or plasma specimens. This kit is intended for use as an aid in the diagnosis of syphilis.\nPrinciple\nThe Syphilis Rapid Test Device (Serum/Plasma) detects IgM and IgG antibodies to Treponema Pallidum (TP) through visual interpretation of color development on the internal strip. Specific recombinant TP antigens are immobilized on the test region of the membrane. During testing, the specimen reacts with recombinant TP-specific antigen conjugated to colored particles and precoated onto the sample pad of the test. The mixture then migrates through the membrane by capillary action and interacts with reagents on the membrane. If there are sufficient antibodies to Treponema Pallidum (TP) in the specimen, a colored band will form at the test region of the membrane. The presence of this colored band indicates a positive result, while its absence indicates a negative result. The appearance of a colored band at the control region serves as a procedural control, indicating that the proper volume of specimen has been added and membrane wicking has occurred.\nSpecimen Collection:\nFor serum, collect blood into a container without anticoagulant. Allow the blood to clot and separate the serum from the clot. Use the serum for testing.\nIf the specimen cannot be tested on the day of collection, store the serum specimen in a refrigerator or freezer.\nBring the specimens to room temperature before testing. Do not freeze and thaw the specimen repeatedly.\nTest Procedure:\n1.Allow the sealed Anti-Syphilis test Device, serum specimens and control solution to reach room temperature (18-30°C).\n2.Remove the test device from the sealed pouch.\n3.2.Using the provided disposable pipette, transfer 3 drops of serum/plasma specimen (approximately 75 µL) to the specimen well (S) of the device and start the timer.\n4.Wait 10-15 minutes and read results. Do not read results after 20 minutes\nSpecimen:Plasma/Serum Sensitivity: >99% Accuracy: >99% Model No: TP-P02B Certificate: CE, ISO9001, ISO13485 Read Time: in 15 minutes", "pred_label": "__label__POS", "pred_score_pos": 0.6027599573135376} +{"content": "I refer to the article, \"S'pore explores all options with nurses in short supply\" (July 11), and the letter, \"Train S'porean women to be nursing aides\" (July 14).\nGiven the need to grow the local nursing workforce, I find it ironic that my daughter, who is deeply passionate about becoming a nurse, has been rejected from nursing courses in polytechnics.\nThis is because she failed mathematics in her O levels with a D7 score, while the course requires a C6 grade or above.\nShe even retook the O-level maths exam just to be able to enrol in a nursing course, but as she has no flair for the subject, she once again scored a D7.\nI would appreciate if the authorities could clarify why nursing courses in polytechnics require a pass for O-level maths?\nThe entry requirements state that one needs at least a D7 for English and a higher grade of C6 for maths.\nMy niece graduated this year from Ngee Ann Polytechnic's nursing course.\nShe mentioned that one needs to know only simple calculations using formulas for the computation of intravenous drugs.\nI am confident that my daughter would make a good nurse even though her maths skills are sub-par.\nAfter all, will the concepts learnt in O-level maths be used in a nurse's daily working life?\nI would think that English is more important as it is needed for communication.\nI urge the authorities to review the entry requirements so they are more relevant to current times and needs.\nAbdul Rahim Darman", "pred_label": "__label__POS", "pred_score_pos": 0.9214738011360168} +{"content": "Non-communicable diseases (NCDs) contribute to 71% of all deaths globally and disproportionately affect people in low- and middle-income countries. SUNI-SEA project aims at tackling NCDs through the synergy between community and primary healthcare facility. An evidence-based research is conducted in Indonesia, Myanmar and Vietnam looking at effectiveness, cost-effectiveness as well as best practices.\nThis video highlighted the vision and progresses we have made in 2019-2020. The team are currently implementing the prospective phase of the project. The overall findings will contribute to the global NCD evidence based and the data can be used for improving health policies, access to healthcare and provision of early NCD intervention, to ensure a better health for all.", "pred_label": "__label__POS", "pred_score_pos": 0.9437925815582275} +{"content": "The world is becoming increasingly diverse. Yet, many people still hold on to the beliefs that “different in dangerous”. Understanding the importance of a diverse and inclusive society can influence us to take action and stop ignorance and hate from spreading. (Estimated reading time: 7-8 minutes) “Our ability to reach unity in diversity will be…\nArchives for August 2017\nBeing a beginner is uncomfortable. It demands more attention, care and a willingness to make mistakes. But the only way to make progress in life is by engaging in new learning. Every master was once a beginner who ploughed through the discomfort. Take these five steps to become a good beginner who learns things quickly…\nTradition brings a sense of belonging and comfort. It brings families and friends together in a spirit of kinship. However, we need to balance tradition with our independent thought. When our customary ways of doing things become restrictive and block our growth, we need to revisit them and question if they’re still working for us…\nFinding your tribe will not only affirm your sense of identity and validate your belief system, but it will give you a sense of home. If you’ve always wanted to find your own tribe, this post provides five steps to find these special people. (Estimated reading time: 7 minutes) “Call it a clan, call it…", "pred_label": "__label__POS", "pred_score_pos": 0.5236292481422424} +{"content": "Over the last decade, tightening regulations have increased the number of documents in the mortgage process, leading to the efficiency of a mortgage underwriter plummeting. Underwriter productivity has decreased from an average of 193 applications per underwriter per month in 2002, to only 27 per month in 2017 (Stratmor Group). That is just over one underwrite per work day, and companies in mortgage have carried the cost of that efficiency decrease.\nInstead of being able to focus on the more complex side of the origination process, underwriters are being bogged down in manual data entry and the “stare and compare” of documents. They now spend up to 80% of their time checking data, and only 20% of their time on risk assessment.\nHowever, technology can now change all that.\nSee how Capsilon Digital Underwriter, a new mortgage solution developed in collaboration with Home Point Financial, can increase underwriting capacity and minimize risk, with automation tools that calculate income, analyze credit, and assess eligibility based on business rules. Learn how the Capsilon Digital Underwriter platform empowers underwriters to make rapid, informed loan eligibility decisions, by minimizing or removing the redundant manual work, allowing them to not only underwrite more loans, but do so more effectively.\nNOTE: This is replay of a previously recorded HousingWire Webinar. Cost: $0.00 Publisher: HousingWire Original Webinar Date: April 24, 2019\nWatch an on-demand replay:", "pred_label": "__label__POS", "pred_score_pos": 0.5679243803024292} +{"content": "Hot water cylinders are a crucial appliance when it comes to heating systems, they store and heat hot water until it is needed. In the UK, there are two main types of hot water cylinders available: vented and unvented. The type of cylinder you need is heavily dependant on your the type of boiler and heating requirements you have. Vented vs Unvented Cylinders: What is the difference? Vented Hot Water Cylinders\nThese cylinders require a cold water tank, which is usually installed in a loft. The water travels down from the tank to the hot water cylinder. As the water heats up, it expands, which is why vent pipes and the tank offers to store the excess. The hot water is also stored in the cylinder until you need it.\nThe reason they need to be installed in the loft is becuase they heavily rely on gravity and the higher the cylinder is placed, the more powerful the water pressure is.\nUnvented Hot Water Cylinders\nWhen unvented cylinders are installed, heating engineers carefully connect this to the mains. Due to this, you do not require a water in in your loft but alongisde your boiler, creating a stronger pressure for your water. They do not have a tank or vent pipe to take care of the excess when the water heats and expends, which is why they have an expension unit or an air bubble to deal with this.\nThe greatest advantage for both these cylinders is that they can be heated directly with an immersion heater in the cylinder, by the boiler or even a solar thermal system.\nSo which one should you choose?\nWhen choosing a cylinder, there are a few things that you need to take into consideration which will help you make your decision. This includes:\n- How strong is your existing mains pressure?\n- How big is your house?\n- How much will is cost to install and maintain?", "pred_label": "__label__POS", "pred_score_pos": 0.5275064706802368} +{"content": "Dental Sealants (Cavities)\nDisparities still exist. Low-income children without sealants have about 60% more cavities in their 1st permanent molars than higher-income children.\n82% of low-income children without dental sealants had cavities in their first molars, compared to 52% of higher-income children without sealants.\nAmong children with sealants, 29% of low-income children had first molar cavities compared to 19% for higher-income children.\nData from NHANES 1999–2004 and 2011–2014.", "pred_label": "__label__POS", "pred_score_pos": 0.9998964071273804} +{"content": "28/3/21\nKey considerations on the potential impacts of the COVID-19 pandemic on antimicrobial resistance research and surveillance\nRodríguez-Baño, Jesús; Rossolini, Gian Maria; Schultsz, Constance; Tacconelli, Evelina; Murthy, Srinivas; Ohmagari, Norio; Holmes, Alison; Bachmann, Till; Goossens, Herman; Canton, Rafael; Roberts, Adam P; Henriques-Normark, Birgitta; Clancy, Cornelius J; Huttner, Benedikt; Fagerstedt, Patriq; Lahiri, Shawon; Kaushic, Charu; Hoffman, Steven J; Warren, Margo; Zoubiane, Ghada; Essack, Sabiha; Laxminarayan, Ramanan; Plant, Laura\nTransactions of The Royal Society of Tropical Medicine and Hygiene, trab048 (2021)\nAntibiotic use in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients during the COVID-19 pandemic has exceeded the incidence of bacterial coinfections and secondary infections, suggesting inappropriate and excessive prescribing. Even in settings with established antimicrobial stewardship (AMS) programmes, there were weaknesses exposed regarding appropriate antibiotic use in the context of the pandemic. Moreover, antimicrobial resistance (AMR) surveillance and AMS have been deprioritised with diversion of health system resources to the pandemic response. This experience highlights deficiencies in AMR containment and mitigation strategies that require urgent attention from clinical and scientific communities. These include the need to implement diagnostic stewardship to assess the global incidence of coinfections and secondary infections in COVID-19 patients, including those by multidrug-resistant pathogens, to identify patients most likely to benefit from antibiotic treatment and identify when antibiotics can be safely withheld, de-escalated or discontinued. Long-term global surveillance of clinical and societal antibiotic use and resistance trends is required to prepare for subsequent changes in AMR epidemiology, while ensuring uninterrupted supply chains and preventing drug shortages and stock outs. These interventions present implementation challenges in resource-constrained settings, making a case for implementation research on AMR. Knowledge and support for these practices will come from internationally coordinated, targeted research on AMR, supporting the preparation for future challenges from emerging AMR in the context of the current COVID-19 pandemic or future pandemics.", "pred_label": "__label__POS", "pred_score_pos": 0.989205539226532} +{"content": "If you're new to saving it can be hard to know where to start. Here are 5 ways to get into the habit.\nCreate a budget\nIdentify opportunities to save by creating a budget, if you don’t already have one. We show you how here.\nKeep savings separate from regular income\nIt's often easier to build up savings if you keep them in a dedicated savings account, and separate them from your everyday banking.\nGet into a savings habit by putting a regular amount each month into a savings account\nUse a personal finance or banking app to monitor and track what you spend. Frequent, small purchases soon add up, and you may spot areas to cut back on spending and save more instead.\nSave a little and often\nSaving any amount of money, however small, is worthwhile. It can help you get into the habit of saving. You could make saving easier by setting up an automated transfer, from your main bank account into a savings account, for the same day each month. Choose the day you're paid, and you'll save money before you're tempted to spend it.\nCompare and save\nUse comparison sites to check if you could be paying less for your household expenses, like utilities, phone, internet or groceries. If you switch to a cheaper deal, try putting the amount you’ve saved each month into your savings account.\nFinancial wellbeing\nHSBC has partnered with Everfi to create a series of modules on a variety of topics, including Savings, Banking, Credit Cards & Interest Rates, Credit Scores, Financing Higher Education, Renting vs. Owning, Taxes and Insurance, Consumer Protection, and Investing, giving you the tools to better manage your financial future. We hope these interactive digital modules can support your choices.\nAdditionally, HSBC has created the YourMoneyCounts financial wellness program which is presented by HSBC staff to the community in a classroom setting. Participant workbooks covering Budgeting, Credit, and Identity Theft and a budgeting worksheet are found through the YourMoneyCount link above. This program was created in partnership with the national nonprofit Greenpath Financial Wellness, and they provide free individualized support focused on your personal situation and financial wellness.", "pred_label": "__label__POS", "pred_score_pos": 0.8788565397262573} +{"content": "Influential metaphors for understanding the environment serve as a bridge between traditional conservatism and outright ecofascism.\nWe have so far introduced the ideas of thinkers we find useful, such as Murray Bookchin’s philosophy of technology, and James O’Connor’s notion of the second contradiction. Here we want to look at how ecological ideas can be deployed to support deeply reactionary politics. We will do this with a critical introduction to the oft-cited, though less often read, biologist Garrett Hardin.", "pred_label": "__label__POS", "pred_score_pos": 0.9870677590370178} +{"content": "Climate change is expected to alter regional hydroclimates, with consequences for water availability and extreme events such as floods and droughts. Past and future changes in hydroclimate remain uncertain over many regions, despite much effort to understand the different aspects of hydroclimate, including precipitation and evaporation patterns. Recent advances in modelling and observational records offer opportunities to revisit hydroclimatic changes to better inform water and risk management and planning decisions. This session invites contributions exploring past and future hydroclimatic changes both in Australia and globally. We welcome a broad range of studies using observations and models, as well as approaches such as machine learning.\nKey topics: Climate change, Trends, Water resources, Extreme events", "pred_label": "__label__POS", "pred_score_pos": 0.586355447769165} +{"content": "Natural disasters affected about 94.94 million people in China over the first three quarters of this year, with direct economic losses of $44 billion, the country's Ministry of Emergency Management said Sunday.\nIn a report, the ministry stated that about 5.26 million people were relocated to safe places during the Jan.-Sept. period, due to extreme weather-triggered disasters.\nChina experienced extremely heavy rainfall 39 times in the first three quarters, leading to floods and road waterlogging, especially in the provinces of Henan and Shaanxi, according to the ministry.\nEarthquakes, typhoons, droughts, snow disasters and forest fires also caused damage to various extents.\nHowever, the overall impact of natural disasters over the past nine months was smaller than during the same period over the past five years, with the affected population and direct economic losses down 31 percent and 14 percent, respectively.\nSource: Jordan News Agency", "pred_label": "__label__POS", "pred_score_pos": 0.9716588258743286} +{"content": "Click here to view the original article and list of winners.\nVayyar, the global leader in 4D imaging radar, has been honored at the Automotive News PACE Awards, with its best-in-class in-cabin solution earning a coveted accolade in the ‘Innovations to Watch’ category.\nThe annual awards, now in their 27th year, evaluate a wide range of industry innovations addressing challenges ranging from electrification and autonomy to road safety.\nThe judging panel recognized Vayyar’s leading-edge automotive-grade in-cabin monitoring platform, which enables OEMs and Tier 1s to meet rapidly rising safety standards, reduce complexity and cut costs for entry-level cars and high-end models alike. With its flagship ‘multifunctionality on a single-chip platform,’ Vayyar technology is driving a paradigm shift that’s making high-end safety affordable and achievable for all vehicles.\nThe 4D imaging radar-based hardware-software platform is the first to cover three rows, footwells and the trunk with one chip, detecting up to eight passengers. In addition to its detection capabilities, Vayyar’s platform differentiates between children and adults, as well as people and objects. It offers a lifesaving Euro NCAP-compliant Child Presence Detection (CPD) and Seat Belt Reminder (SBR) combo, while also enabling features including advanced eCall, seatbelt pretensioners indications, optimized airbag deployment, occupant status, intruder alerts and more.\nVayyar’s high-performance, single-chip 4D imaging radar supports an ultra-wide field and unparalleled imaging resolution, minimizing false alarms and replacing up to seven other in-cabin safety sensors. Just one RFIC can earn any vehicle 7.5 Euro NCAP safety points, enhancing safety while reducing costs.\nSince the platform is not based on cameras or optics, it doesn’t require line of sight and maintains privacy at all times. Production-ready, it’s AEC-Q100 qualified, ASIL-B compliant and projected to save countless lives.", "pred_label": "__label__POS", "pred_score_pos": 0.8758845329284668} +{"content": "Murialdo Maxwell | 19-LW-056 Project Overview\nFour-dimensional (4D) printing adds a new dimension to additive manufacturing, specifically, the ability for an object to transform its shape after it has been printed. These prints are often comprised of shape memory polymers, which are actuated by heating, sometimes using resistive heating from electric currents through the filament. However, the applications of 4D prints have been limited by the crudeness of their actuation methods. Controllably actuating only specific regions of a 4D print using internal mechanisms (e.g., electrical resistive heating) has proven challenging. Nevertheless, the precise signal control offered by percolating electronics would exponentially amplify the versatility of 4D prints by allowing for complex, origami-inspired transformations of fully printed parts, orchestrated in real time.\nWe investigated a new paradigm for controlling the actuation of a 4D print using internally propagated signals. This new approach (i.e., percolating electronics) entails mixing micron-scale, high-aspect-ratio active electronics components known as chiplets into 4D-printable feedstock inks prior to printing. The active electronics are designed to form randomly percolating electrical pathways within the feedstock ink itself. These electrical pathways have built-in logic components that allow an operator to selectively address and actuate individual regions of a 4D-printed object in real time, without the need for post-processing.\nIn this project we conceptualized, designed, fabricated, characterized, and tested the fundamental components necessary for signal control by percolating electronics. Our steps included (1) simulating high-aspect-ratio chiplets subjected to the shear flows present in a non-Newtonian ink extruded by direct-ink-write (DIW) printing; (2) designing and simulating a finite-state-machine (FSM) circuit to control each chiplet; (3) fabricating and testing this complementary metal-oxide-semiconductor (CMOS) circuit; (4) fabricating over one million chiplets on silicon wafers; (5) developing and implementing a chiplet-release protocol; (6) characterizing the chiplets; and (7) studying the printability of mock-chiplet-loaded inks. These experiments indicate the viability of using signal control of percolating electronics for numerous applications.\nMission Impact\nThis project builds on Lawrence Livermore National Laboratory's core competency in advanced materials and manufacturing. The percolating electronics signal control paradigm studied in this project can be applied to (co-printed with) many advanced printable inks developed at the Laboratory and elsewhere, including reactive/energetic inks, gas-absorbing inks, biological-substrate inks, catalysis-substrate inks, color-changing inks, and porous inks. Potential applications of the technology include medical devices, wearables, soft robotics, adaptive packaging, self-assembling structures, custom adaptive parts, tunable mechanical properties, and safety controls.\nPublications, Presentations, and Patents\nMaxwell Murialdo, Y. Kanarska, and Andrew Pascall. 3D Printable Feedstock Inks for Signal Control or Computation. U.S. Patent Application No. 16/219,188.\nKanarska, Y., et al. 2020. \"Numerical Simulations of Conductive Percolating Chiplets Embedded in a Non-Newtonian Polymer Subjected to a Shear Flow.\"\nJournal of Non-Newtonian Fluid Mechanics 286. LLNL-JRNL-802729", "pred_label": "__label__POS", "pred_score_pos": 0.6726617813110352} +{"content": "Abstract Date Presented 04/05/19\nThe purpose of this phenomenological study was to explore how individuals with Parkinson’s disease (PD) perceived noncontact boxing to influence their social and community engagement. This study found that those with PD who perceived noncontact boxing positively were positively influenced by it in both their social engagement and their physical and cognitive abilities. This study supports the feasibility of clinicians to utilize community-based, movement-focused activities to assist in the management of PD symptomology.\nPrimary Author and Speaker: Casey Humphrey Additional Authors and Speakers: Dana Howell Contributing Authors: Melba Custer", "pred_label": "__label__POS", "pred_score_pos": 0.9681528806686401} +{"content": "The Police in Gulu has rallied the public to back up theircommunity policing efforts to curb a new wave of gang rape and defilementcases.\nThis follows an increase in the activities of criminal youth gangs.The offenders flout restrictions on night movements, waylay young girls andkidnap them.\nMoses Ogwang, the Gulu City Community Liaison Officer disclosedthat the criminal gangs abduct their victims into rented rooms usually inisolated locations where they commit their acts especially in the outskirts ofGulu City Divisions.\nOgwang revealed that many parents have relinquished parentalobligations leaving children with a lot of liberty to control themselves whichpropels them into conflict with the law.\n//Cue in...\"Parents have left….”\nCue out… area of Layibi.”//\nBallingtone Ongwech, the Secretary for Health, Education and Community Servicessays needy parents are threatening leaders who try to investigate rape,defilement and early marriages in the community, a trend that will make it hardto stamp out the vice.\n//Cue in...\"Parents would….”\nCue out… they are there.”//\nThe Community Development Officer, Goretti Oketch, regretted that no arrestshave so been made to bring the perpetrators to book. She emphasized the needfor different partners and the district to collaboratively devise acomprehensive strategy to eradicate the vice.\n//Cue in...\"Parents would….”\nCue out… they are there.”//\nThe leaders are worried that if the trend of such crime is not averted, it willaggravate teenage pregnancies and child marriages in Aswa Region.\nAccording to the police statistics, over 2,000 underage girls have been defiledand impregnated in Gulu alone, while the statistics are over 20,000 for theentire Acholi sub-region during the period of lockdown spanning March 2020 toAugust 2021.\nAnnually, sexual offences including rape and defilement top thepolice annual crime reports.\nFor instance, in 2020, the crime indicates that a total of 1,521women were victims of rape. However, up to 1,519 cases were registered unlike 1,528cases in 2019.\nAccording to the Center for Domestic Violence Prevention –CEDOVIP, a local civil society organization committed to preventing violenceagainst women in 2018, at least 644 cases were taken to court, and 16 securedconvictions, with one case acquitted, seven dismissed and 620 cases pending,and 618 were still under investigations.", "pred_label": "__label__POS", "pred_score_pos": 0.8160414695739746} +{"content": "Measuring Interoception: The CARdiac Elevation Detection Task Ponzo S., Morelli D., Suksasilp C., Cairo M., Plans D.\nInteroception has increasingly been the focus of psychiatric research, due to its hypothesized role in mental health. Existing interoceptive tasks either suffer from important methodological limitations, impacting their validity, or are burdensome and require specialized equipment, which limits their usage in vulnerable populations. We report on the development of the CARdiac Elevation Detection (CARED) task. Participants’ heart rate is recorded by a wearable device connected to a mobile application. Notifications are sent to participants’ mobile throughout the day over a period of 4 weeks. Participants are asked to state whether their heart rate is higher than usual, rate their confidence and describe the activity they were involved in when the notification occurred. Data (N = 30) revealed that 1/3 of the sample was classified as interoceptive and that participants presented overall good insight into their interoceptive abilities. Given its ease of administration and accessibility, the CARED task has the potential to be a significant asset for psychiatric and developmental research.", "pred_label": "__label__POS", "pred_score_pos": 0.6043137311935425} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis comprehensive guide on preventing child abuse and neglect uses a strength-based framework and recognizes that there are actions we can take to address root causes and provide meaningful support. The guide provides information on resources and partners, and how to build protective systems and policies using a public health approach, acknowledging families' lived wisdom.\nThis newly updated and expanded report provides a framework for understanding social and emotional learning (SEL). It can be used as a reference to compare the content and evidence of effectiveness of 33 SEL programs for elementary-age and preschool-age children.\nThis report provides a synthesis of 76 high quality studies on the impact of COVID-19 on young children and early childhood education programs. The studies and accompanying evidence-based and equity-centered policy recommendations were created by 10 leading scholars and 10 leaders in policy and practice for early childhood.\nThis report provides a seven-step equity and inclusion framework for understanding different dimensions of racism. It addresses how to identify and analyze the root causes of racial inequities and how to establish shared values and a common understanding to advance and embed race equity and inclusion in an organization.\nThis report summarizes survey data collected in 2020, both before and during the pandemic; it is the fourth survey, preceded by findings from 2004, 2009, 2014.\nThis report captures what was shared at an October 2019 Conference about the challenges of teaching social and emotional learning (SEL) in afterschool programs. It provides a brief history of the growing focus on SEL, along with a summary of remarks by national leaders.\nThis report is the third edition that investigates how the early childhood education (ECE) field is cultivating leaders within the field. Based on a survey, it examines the role of 57 self-identified leadership development programs in supporting staff learning of leadership skills.\nWith an emphasis on equity and inclusion, this white paper outlines promising practices for engaging families in STEM as a means of increasing youth participation and retention in STEM pathways. Parents play a critical role in engaging youth in STEM activities and careers, especially for girls, youth of color, low-income youth, and youth with disabilities.\nThis report aims to challenge the prevailing discourse about Black children from one that overemphasizes limitations and deficits to one that draws upon strengths, assets, and resilience.\nThis classic report clarifies the cost of quality out-of-school time programs, based on data from 111 quality programs in six cities. It provides the mean and range for hourly and daily cost per slot, with an analysis of factors that bring differences to cost.", "pred_label": "__label__POS", "pred_score_pos": 0.884009063243866} +{"content": "Cosmetic Testing on Animals\n213.4 x 213.4 cm\nNot For Sale\nCosmetic testing on animals is an issue that has been going on for a while, and has recently become a more public issue. It is the practice of testing beauty products on animals to deem the safety of the product for consumers. This can range from shampoos, makeup, perfume, and lotions. In the United States, a large percentage of the animals used in cosmetic testing are laboratory-bred rats and mice, rabbits, and guinea pigs, all of which receive no protection under the Animal Welfare Act. I choose this topic because I believe strongly there is no need for this practice anymore. We have plenty of technology that could help us determine whether a product is safe, instead of involving innocent lives. These poor animals, after these tests, face death either by asphyxiation, neck-breaking or decapitation, and pain relief is not provided. The sad thing about this is that the results from these tests often come back inconclusive and don’t really help with figuring out if the product is safe for consumers. I want to bring light to this topic because I really want to be aware as a consumer what type of companies I am supporting, and want to help people realize they can stop this issue by using the power of their wallet, not supporting companies who practice inhumane practices for their products.\nExhibitions with this piece Unmute Joining the conversation on world matters, virtually.\nThe ASU Visual Communication Design Class of 2021 is thrilled to launch the first ever virtual senior exhibition, Unmute. This project is a culmination of months of work, forty-four passionate designers, two supportive professors, and a dedication to learn more about the world around us - all while collaborating and designing entirely online. Join us virtually, as we’ve partnered with VR-All-Art to create an immersive, interactive exhibition experience. Use the arrows on your keyboard to explore the virtual space, walking through each student’s unique exhibit. Click on highlighted items on each panel to dive deeper into the conversation.", "pred_label": "__label__POS", "pred_score_pos": 0.5083020925521851} +{"content": "As market volatility continues, investors are looking for the currencies where central banks are raising interest rates. Paths of monetary policy are still highly dependent on how successful the economies fight against the new delta strain and the potential risks from a fresh autumn wave. The Reserve Bank of Australia was the first bank to indicate that scaling back asset purchases may be premature at this point. The Bank of Canada keeps policy on hold while monitoring closely. The European Central Bank intends to slow its PEPP’s asset purchases.\nRBA extends Asset Purchases to support Recovery\nThe Reserve Bank of Australia kept the interest rate at 0.10% in its September meeting as widely expected. However, the policy statement reflected a shift in the bank’s evaluation of the economy during the coming months. The bank stated that recovery in the Australian economy has been interrupted by the Delta outbreak and the associated restrictions on activity. GDP is expected to decline in the third quarter and the unemployment rate will move higher over coming months.\nThe statement acknowledged that prior to the Delta outbreak the Australian economy had considerable momentum with GDP increasing by 0.7% in the June quarter and by nearly 10% over the year. Business investment was picking up and the labour market had strengthened. The unemployment rate had fallen below 5% and job vacancies were at a high level.\nThe bank has kept its optimistic view of the economy, stating that this setback to the economic expansion is expected to be only temporary. The Delta outbreak is expected to only delay the recovery. It sees the economy bouncing back as vaccination rates increase and restrictions are eased.\nDue to the recent economic developments, the bank announced an extension to the bond purchases at a weekly pace of $4 billion until at least February 2022. The decision reflects the delay in the economic recovery and the increased uncertainty associated with the Delta outbreak.\nThe board expects the economy to pursue its growth again in the December quarter and is expected to be back around its pre-Delta path in the second half of next year. And again, the statement stressed that the conditions for raising rates will not be met before 2024.\nBoC Cautiously on Hold\nThe Bank of Canada held its overnight interest rate at 0.25% in line with forecasts, and maintained its asset purchases at $2 billion per week, following a $1 billion cut in the previous meeting. The bank expects the economy to strengthen in the second half of 2021, after a 1% contraction in the June quarter. Although the fourth wave of COVID-19 infections and ongoing supply disruptions could weigh on the recovery.\nThe central bank sees the inflationary pressures as transitory, but their persistence and magnitude are uncertain and will be monitored closely.\nThe BoC judges that the recovery still requires extraordinary monetary support as the Canadian economy still has considerable excess capacity. While reiterating its commitment to hold the interest rate at the effective lower bound until economic slack is absorbed so that the 2% inflation target is achieved. In the Bank’s July projection, this happens in the second half of 2022.\nECB Tapers Bond Buying under PEPP\nThe European Central Bank will conduct a moderately lower pace of net asset purchases under the pandemic emergency purchase programme (PEPP) than in the previous two quarters. During its September’s meeting, the bank decided to keep the interest rates on the marginal lending facility and the deposit facility unchanged at 0.00%, 0.25% and -0.50% respectively.\nThe bank expects inflation to stabilize at 2% over the medium term, after a transitory period in which inflation is moderately above target.\nMeanwhile, the bank will continue net purchases under the APP at a monthly pace of €20 billion. The Council expects asset purchases under the APP to run for as long as necessary to reinforce the accommodative impact of its policy rates, and to end shortly before it starts raising the key ECB interest rates.\nThe ECB also updated its growth and inflation forecasts. Inflation is now seen at 2.2% in 2021 vs 1.9% estimated in June, 1.7% in 2022 vs 1.5%, and 1.5% in 2023 vs 1.4% previously. The bloc’s growth is expected to expand by 5% in 2021 vs 4.6%, for 2022 growth was downgraded from 4.7% to 4.6% and forecasts for 2023 growth was maintained at 2.1%.\nJoin the Market and Trade the News\nStart trading today! Choose now from various forex account types, based on your trading strategy, experience, and capital designed for investment. Explore the best trading conditions with AximTrade, a global leading broker with flexible leverage up to 1:3000, which is one of the top competitive leverage conditions.\nAximTrade is a fast-growing brokerage service provider in the global markets with a highly advanced MT4 execution and CopyTrade platform. One of the core values of AximTrade is to enable forex traders with easy-to-use technology, educational resources, technical analysis, ongoing promotions, and a highly competitive trading environment with the best trading conditions. Learn how to open forex account with easy few steps and join the financial markets now!", "pred_label": "__label__POS", "pred_score_pos": 0.6245124340057373} +{"content": "Background Existence of inequalities in quality and access to healthcare services at subnational levels has been identified despite a decline in maternal and perinatal mortality rates at national levels, leading to the need to investigate such conditions using geographical analysis.The need to assess the accuracy of global demographic distribution datasets at all subnational levels arises from the current emphasis on subnational monitoring of maternal and perinatal health progress, by the new targets stated in the Sustainable Development Goals.Methods The analysis involved comparison of four models generated using Worldpop methods, incorporating regionspecific input data, as measured through the Community Level Intervention for Pre-eclampsia (CLIP) project.Normalised root mean square error was used to determine and compare the models’ prediction errors at different administrative unit levels.Results The models’ prediction errors are lower at higher administrative unit levels. All datasets showed the same pattern for both the live birth and pregnancy estimates.The effect of improving spatial resolution and accuracy of input data was more prominent at higher administrative unit levels.Conclusion The validation successfully highlighted the impact of spatial resolution and accuracy of maternal and perinatal health data in modelling estimates of pregnancies and live births. There is a need for more data collectiontechniques that conduct comprehensive censuses like the CLIP project. It is also imperative for such projects to take advantage of the power of mapping tools at their disposal to fill the gaps in the availability of datasets for populatedareas.", "pred_label": "__label__POS", "pred_score_pos": 0.8919672966003418} +{"content": "Although waste is typically associated with industrial businesses, it should be noted that the mitigation of environmental pollution begins at the most basic level. And that level is at the residential stage. In the grand scheme of things, you may think that your household does not contribute to the degradation of the planet when, in truth, the more the population grows, the higher the number of households and the residential waste produced attributes to a substantial percentage of environmental contamination.\nFortunately, you can be responsible for your residence's garbage by investing in devoted waste management. Hiring the professionals not only ensures that the garbage is eliminated from your premises but that it is recycled and disposed of through the correct channels. This article outlines compelling reasons to hire dedicated garbage removal services for effective recycling.\nConservation of energy\nAlthough there are numerous sources of energy on the planet, trees remain the leading resource utilised for a multitude of manufacturing industries. From cartons as food packing to paper cutlery, this material is not only widely used but it is also widely present in the garbage. To manufacture new paper items, fresh trees need to be cut down and this can contribute to deforestation if the felling is not undertaken responsibly. Secondly, processing and manufacturing of the lumber to create paper products consume a considerable amount of water and energy, which also results in the production of toxic emissions that pollute the planet.\nAll of this can be reduced by engaging in property waste recycling. A professional garbage collection company will ensure that your waste is sorted meticulously so that all recyclable items are salvaged and this can help with limiting the dependence on freshly manufactured paper items while conserving a substantial amount of energy in the process.\nLimiting land pollution\nWhile sorting your garbage may seem straightforward, this is not always the case. More often than not, some homeowners will either overlook this step or simply be unaware of what items can be recycled and those that cannot. As a result, when the waste is eliminated, non-biodegrade items, for example, plastics and rubber supplies, end up in landfills, taking up more space than they are supposed to. Over time, the need for new landfills grows as the pre-existing ones are getting full.\nInstead of contributing to the filling of the landfills, it is best to enlist garbage disposal services for guaranteed efficiency with the recycling process. The professionals will be painstaking about ensuring non-biodegradable items are discarded appropriately. Consequently, you proactively help with reducing both land contamination as well as the pollution of the ocean and other water bodies. Look for a disposal service that offers recycling options.", "pred_label": "__label__POS", "pred_score_pos": 0.7585675716400146} +{"content": "Study identifies sulfatase, a potential drug target for inflammatory bowel disease and colorectal cancer\nEnzyme is behind the breakdown of the protective mucus barrier in the gut\nA new study published in\nNature has found that a single sulfatase contributes to the degradation of mucus that protects the intestinal lining, potentially leading to inflammatory bowel disease (IBD) and colorectal cancer.\nThe human gut microbiota significantly impacts several aspects of intestinal health and disease, including inflammatory bowel disease and colorectal cancer. In the colon, secreted mucus creates a barrier that separates gut microorganisms from the lining of the intestine, preventing close contact that can lead to these conditions.\nSome gut bacteria are able to use mucin glycoproteins, the main mucus component, as a nutrient source. However, it remains unclear which bacterial enzymes initiate degradation of the complex O-glycans found in mucins.\nDespite the critical roles of sulfatases in many biological processes, including diseases, the researchers from a group of universities including the University of Liverpool, University of Gothenburg, and the University of Michigan aimed to address the significant knowledge gap regarding their specificity and mechanisms.\nA major component of colonic mucus is mucin 2, a glycoprotein. Mucin glycosylation is variable along the gastrointestinal tract, with an increase in sulfation in the colon, especially in the distal colon.\nTo degrade the complex O-glycans found in mucins, some human gut bacteria have evolved complex arsenals of degradative enzymes that include sulfatases.\nBy characterizing the activity of 12 different sulfatases, researchers were able to show that sulfatases are essential to the utilization of distal colonic mucin O-glycans by the human gut symbiont\nBacteroides thetaiotaomicron.\nThe study reveals that\nB. thetaiotaomicron has a robust ability to grow on highly sulfated colonic mucin and that it possesses sulfatases capable of removing sulfate groups in all contexts in which they are known to occur in mucin. Surprisingly, researchers found that a single key sulfatase is disproportionately important for growth on colonic mucin O-glycans.\nThe findings support a critical role for active sulfatases in both normal colonization and inflammation.\nGiven that mucin glycan structures may vary between mammalian hosts, these critical steps may eventually need to be validated in humans.\nThese findings will inform future research into blocking this complex enzyme pathway and potentially inhibiting mucin-degrading activities in bacteria that contribute to diseases such as IBD.\nPaper cited: “A single sulfatase is required to access colonic mucin by a gut bacterium,”\nNature, DOI: 10.1038/s41586-021-03967-5 Adapted from a press release from the University of Liverpool, UK.", "pred_label": "__label__POS", "pred_score_pos": 0.9855436086654663} +{"content": "A recent study by scientists from the International Livestock Research Institute (ILRI) and partners has identified that the principles of adaptive co-management provides guidance for the design of effective landscape-level governance in dryland pastoral settings. The newly published article draws attention to the cross-scale and cross-level interactions in rangelands and how these affect governance of the landscapes.", "pred_label": "__label__POS", "pred_score_pos": 0.9787137508392334} +{"content": "HART — The Michigan Department of Environmental Quality (DEQ) is taking public comment until May 8 on the city’s proposal to remove the weir boards on Russell Creek.\nThe proposal arises from the DEQ’s claim that the city is violating water quality standards due to the Hart Dam.\nThe DEQ issue stems from temperatures in the south branch of the Pentwater River below the Hart Dam and Russell and Chippewa creeks exceeding 68 degrees. The bodies of water are subject to cold water fisheries standards.\nThe Hart Dam, built in 1927, is the focal point of the city’s hydroelectric system. It is one of just a few municipal hydroelectric operations in West Michigan.\nA public notice published by the DEQ states that the city “proposes to remove boards from an existing weir on Russell Creek, removing four foot boards to lower the weir by 1.8 feet, and lower the surface water level on Russell Creek at the location adjacent to Mechanic Street. This activity will lower the water level by approximately 1.8 feet within the shallow water impoundment from Johnson Street to Mechanic Street. This is being proposed as a temporary project for two years to determine if elimination of the impoundment and a return to more natural stream flows will improve temperature and dissolved oxygen parameters in Russell Creek and downstream receiving waters.”\nWritten comments regarding the proposal may be sent to the DEQ by May 8. The address is: State of Michigan Department of Environmental Quality, Water Resources Division, Grand Rapids District Office, 350 Ottawa Ave., NW, Unit 10, Grand Rapids, MI, 49503-2341.\nComments can also be made electronically, and the public notice can be viewed at https://miwaters.deq.state.mi.us/miwaters/#/external/publicnotice/search.", "pred_label": "__label__POS", "pred_score_pos": 0.5107783079147339} +{"content": "Abstract\nWater reservoirs are essential for regional economic development, as populations depend on them for agriculture irrigation, flood control, hydroelectric power generation, water supply for human consumption, and subsistence fishing activities. However, the reservoir environmental quality can be disturbed by enhanced sediment input and trace metal contamination, affecting human health as a consequence of contaminated water and fish consumption. With the purpose to understand the trends and extent of sediment accumulation and trace element contamination in the Oviachic reservoir (OV, northwestern Mexico) since its construction, the temporal variations of sediment accumulation, and As, Cr, Cu, Hg, Ni, Pb, and Zn concentrations, enrichment, and fluxes, were evaluated through the study of two\n210Pb-dated sediment cores. We assumed that siltation and trace element contamination were driven by the development of anthropogenic activities in the region within the past ~ 70 years. Elemental concentrations accounted from null to minor enrichment for most elements, but moderate to significant enrichment by Hg. Mercury, As, and Cu fluxes have notably increased since the past decade, most likely because of a combination of anthropogenic and natural processes, including catchment erosion, artisanal gold mining, and recent drought conditions in the region. Arsenic and Hg concentrations may pose deleterious risks to biota in the reservoir, and consequently to humans through fish consumption, for which further biological and toxicological tests are advisable. This study highlights the importance of using sediment dating to assess historical trends of metal contamination and identify possible sources, to support decision-making in programs addressed to reduce environmental and health risks in aquatic ecosystems. Bibliographical noteFunding Information:\nThis study was supported by the project grant # 20562 ?Accumulation and distribution of metals and metalloids in water, sediments and biota in the Yaqui River Basin, Sonora State,? from Centro de Investigaci?n en Alimentaci?n y Desarrollo, A.C. The scholarship of R. Ochoa-Contreras was provided by the Consejo Nacional de Ciencia y Tecnolog?a of M?xico. The authors are grateful to Adolfo Americano for the technical assistance during sampling activities and to Germ?n Ram?rez, Carlos Su?rez, and Le?n Felipe ?lvarez for the data curation and processing.\nPublisher Copyright:\n© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.\nKeywords Pb dating Climate variability Sediment accumulation rates Trace element contamination Water reservoirs", "pred_label": "__label__POS", "pred_score_pos": 0.5707617998123169} +{"content": "Our client had to complete an Environmental Due Diligence (EDD) assessment for the sale of an Australian portfolio of medical facilities. The company needed the assessment in a compressed timeframe to ensure the property transaction was completed within the contract deadline, thereby maximising the commercial return for the vendor.\nThe portfolio is comprised 30 medical facilities, including private hospitals, consulting suites and rehabilitation centres that were spread across all Australian States and Territories.\nWSP in Action\nOur role was to assess the potential risk of environmental contamination.\nThe EDD started with a data room assessment and historical property searches and then detailed site inspections. Due to the operational nature of the properties, we spent significant time liaising with the client, vendor and site occupiers. This ensured our inspections had minimal impact on business performance and that we maintained patient privacy and confidentiality.\nTangible Benefits\nOur fast and collaborative approach enabled the vendor to successfully complete the sale.", "pred_label": "__label__POS", "pred_score_pos": 0.768947958946228} +{"content": "Q A community hospital intends to rent clinic space, and the valuations are a year or two old. The hospital believes these valuations are still valid. Is there a specific time period during which a valuation generated as part of a “formal, professional appraisal process” remains valid, before the findings of such a valuation may no longer be considered indicative of fair market value? A The determination of the fair market value of a lease, including reliance on an appraisal, to value the rental of office space and of physician services, is a question of fact that must be determined by the Board of Trustees of the hospital (Attorney General’s Opinion to Dillard, May 26, 2017)", "pred_label": "__label__POS", "pred_score_pos": 0.9300957918167114} +{"content": "Publications Search\nThis\npublications portal is a repository of all IOM migration health publications from 2006 to present where IOM was a primary contributor.\nPublications include peer-reviewed scientific papers, technical reports, training guides/manuals, policy briefs/discussion papers, factsheets, newsletters, research reviews, conference and poster presentations. These are categorized by topic, author, country/region covered as well as by year, language, and type of publication. The map reflects the countries covered by the publications.\nTo browse or search: simply use the filter options on the left-hand side. Alternatively, you can enter keyword/s in the search box. Selecting a specific publication will lead to a ‘download’ link or link to the website where the document is housed. Here is the step-by-step guide for your reference. The integration of livelihood support and mental health and psychosocial wellbeing for populations who have been subject to severe stressors Author/s:Guglielmo Schininà, Elisabeth Babcock, Rachel Nadelman, James Sonam Walsh, Ann Willhoite, Alys Willman\nThis article aims to promote the integration of mental health and psychosocial support into livelihood programmes, presenting existing research within behavioural economics, humanitarian and economic ¢elds that support the need and e¡ectiveness of such integration. It presents examples of mental health and psychosocial support integration into livelihood programmesput in placeby a grass roots organisation in the USA and the largest development institution in the world, theWorld Bank Group,…Read more", "pred_label": "__label__POS", "pred_score_pos": 0.730309784412384} +{"content": "FAQs Why crowdsourcing?\nCrowdsourcing provides an opportunity for the FDA and the public to interact. Crowdsourcing community members can engage with each other and the FDA by posting their ideas or experiences and commenting on the submissions of others. These conversations create an avenue for the FDA to listen to the public and incorporate these perspectives into ongoing initiatives.\nHow do I participate?\nOnce you are logged-in, click the “Submit Research Question” button on the top right-hand corner of the page.\nYou can also view what others have submitted by clicking the “See what others have to say” button.\nCan I participate anonymously?\nYes!\nClick on your username in the top right-hand corner and select “Profile” Scroll down to \"Community Identities\" and check the box under \"Hidden Identity\" in the row labeled \"DPMH Crowdsourcing.\" Click the \"Save Changes\" button above the Community Identities section. (Be careful to not click the “Leave” button as this will remove you from the community). To confirm that your identity is hidden, leave the profile page by clicking on the home icon at the top of the page and then revisit it by following steps 1 & 2 above. The \"Hidden Identity\" box should still be checked. (There is a known bug that shows the \"Hidden Identity\" checkbox as unchecked after you click the \"Save Changes\" button. Refreshing the page may not work to confirm your changes are saved, which is why leaving the page is recommended.)\nYou can also participate anonymously by turning on the “Submit Idea Anonymously” before submitting your post.\nClick the “Submit Research Question” button on the top right-hand corner of the page. Fill out the required fields. Scroll to the bottom of the submission page and turn on the “Submit Idea Anonymously” button prior to submitting. Please note that no matter what option you choose to enable you to participate anonymously, you will still see your name attached to your shared experiences. However, the rest of the community will only see “Community Member” instead of your name.\nWhat are we doing with your data?\nThe information gathered in your registration will not be shared and is only used for log-in and verification purposes.\nThe information you submit and the comments you post will be used to understand the relationship between community participants and pediatric research.\nPlease do not post any personally identifiable information (PII) (such as address, social security number, etc.).\nWho is moderating this site?\nThis site is moderated by the staff in the Center for Drug Evaluation and Research within the U.S. Food and Drug Administration (FDA).\nModerators will facilitate discussions and work to ensure that posts remain respectful. Please be advised that moderators may not always monitor discussions in real time. Due to the potential volume of comments, moderators may not respond to all posts.\nIf you have specific questions, we encourage you to share them via email with our FDA staff at ShareYourVoice@fda.hhs.gov.", "pred_label": "__label__POS", "pred_score_pos": 0.6844556331634521} +{"content": "Get ready for your best sleep yet with nootropic ZZZZs!\nWe all know that getting some quality sleep is crucial to optimize performance. However, sports and athleticism can compromise sleep due to its high stress levels and impact on the body. This type of sleep neglect can alter performance and increase overall stress. Well, Form nutrition came out with a nootropic specifically formulated to get you some quality sleep.\nMake the most out of your days by naturally supporting a regenerative sleep! Key Benefits:\nThis supplement is formulated with a blend of ingredients to support quality sleep naturally by addressing any deficiencies that may be affecting your sleep. It also stimulates a relaxing and calming effect to reduce the time it takes to fall asleep and stay asleep without any disturbance.\nHow We Use It:\nWe like to take one capsule about 30 minutes before bed time to start the journey to the best sleep yet!", "pred_label": "__label__POS", "pred_score_pos": 0.8948333859443665} +{"content": "Corospondent - July 2020\nCoronation Global Managed Strategy - July 2020\nFOLLOWING A RAPID sell-off earlier this year, markets rebounded strongly in the second quarter of 2020 (Q2-20). The stock market recovery has been very much V-shaped, with a gain of 19.2% this quarter following the first quarter’s -21.4% decline, despite continued economic uncertainty and an unclear path to recovery. Nevertheless, this leaves global markets, as measured by the MSCI All Country World Index (ACWI), still down 6% for the year to date.\nThe Strategy returned 12.3% for Q2-20, in line with the benchmark return of 12.8%.\nContributions to performance were broad based, as most risk assets rallied:\nThe Strategy’s equity holdings returned 19.2% (in line with the ACWI). Property returns were also strong at 19.3%. Fixed interest rebounded, returning 4.5% (more than 1% ahead of the benchmark). Gold delivered a 10.6% return, bringing the gain over the last year to over 26%. BULLISH ON STREAMING AUDIO\nSpotify, which more than doubled over Q2-20, was the largest single contributor to returns. We have previously written that the global recorded music industry returned to growth in 2015 after almost two decades of decline. This growth was driven by streaming, which today accounts for the majority of industry revenue. In our view, music remains extremely under-monetised and we are still in the very early stages of streaming industry growth. There are now over 300 million paying music streamers globally, but this is a small portion of the 3.5 billion smartphones in the world today, while headline subscription prices have not changed in years and average revenues per user have in fact declined due to family and student discount plans. In the US, Spotify’s headline price of $9.99 per month is unchanged since its 2011 launch, while music spending per capita has halved in real terms since 1999. As the largest audio platform outside of China, with 130 million paying subscribers and an additional 163 million ad-supported users, we believe the company is well placed for long-term growth. Spotify is significantly larger than its primary competitor (Apple Music, which has between 60 million and 70 million subscribers, with no free, ad-supported tier), and continues to add more subscribers each year due a better product and ongoing innovation.\nWe are also bullish on Spotify’s podcast strategy. Terrestrial radio remains a large advertising revenue pool globally and Spotify is trying to disrupt this, acting decisively and investing in leading podcast creation tools, studios and exclusive content from top podcasters such as Joe Rogan. We believe this strategy is a win-win for all involved, as it increases utility for users, allows podcasters to connect to the largest global audience and monetise their content, and brings significant benefits to Spotify itself, including higher user engagement and additional revenue streams.\nSince 2015, Spotify has grown its revenue by 37% p.a. and we expect strong growth to continue, forecasting growth of over 20% p.a., and steadily expanding margins going forward. In the words of co-founder and CEO Daniel Ek, “Everything linear dies”. As the leading player and innovator in the fast-growing audio streaming market, led by an exceptional management team, we believe Spotify is well positioned to capitalise on this trend.\nTEMPORARY SETBACK\nPhilip Morris International (PMI) was the largest detractor from performance, although with a return of -2.6%, the effect was only marginally negative. PMI is a global tobacco company and the global leader in potentially reduced-risk, next-generation products through its IQOS heated tobacco franchise. IQOS is already contributing about 20% to company revenues. PMI has invested significantly into the IQOS franchise over a sustained period and has built a significant first-mover advantage in the heated tobacco category. IQOS has been a phenomenal success in our view, ranging from truly extraordinary results in Japan to solid, steady progress across many European markets.\nTo date, some 11 million smokers have completely quit smoking combustible cigarettes and moved to IQOS. At the time of writing, the US Food and Drug Administration, probably the preeminent tobacco regulator globally and renowned for its science-led approach to regulation, has just authorised IQOS to be sold in the US with a reduced exposure claim – to the effect that completely switching to IQOS significantly reduces a smoker’s exposure to harmful chemicals.\nImportantly, as IQOS grows, it is accretive to PMI’s revenues and profits. We believe there is still a long runway of growth for IQOS globally. Despite the resilience of tobacco as a consumer category, PMI has not been immune to Covid-19 lockdowns. PMI has been severely impacted by lost duty-free sales, the impact of lockdowns in emerging markets such as the Philippines and Indonesia, and temporarily slower IQOS user conversion. Second-quarter results will be significantly negatively impacted by these factors, but we expect that, over the medium term, these lost sales should be recovered and that IQOS should fairly quickly resume its growth trajectory. PMI remains a top 10 holding.\nPORTFOLIO POSITIONING\nAt quarter-end, the Strategy was positioned with 68% in growth, or risk assets, comprised of the following:\n53% effective equity; 3% in property; 6% in convertible bonds; 3% in high-yield corporate bonds; and 2% in infrastructure.\nThe remaining 32% of the Strategy is invested in more stable, diversifying assets with limited correlation to equities:\n7% in hedged equity; 5% in commodities; and 20% in fixed income, the bulk of which is invested in Treasury Bills (9%), inflation-protected securities (6%) and investment-grade corporate bonds (3%).\nLast quarter, we felt there were attractive opportunities for those investors with a long time horizon and the ability to filter companies whose prices had been dislocated with little impact to their sustainable earnings power. After a sharp rally, these opportunities are now harder to find. In addition, the need to reassess the prospects of many businesses continues as investors parse fundamental virus-induced behavioural changes from short-term noise. Fundamental changes, however, play to the strengths of fundamental investors, and we continue to find a select number of stocks with attractive long-term prospects that are reasonably priced, while appropriately managing exposures across a range of asset classes.\nThank you for your continued support and interest in the Strategy.\n+\nDisclaimer", "pred_label": "__label__POS", "pred_score_pos": 0.533205509185791} +{"content": "Inequality, Deprivation, Punishment and Crime: Theoretical and Experimental Investigations Guest Lecture Date: Jun 14, 2021 Time: 16:00 Speaker: Prof. Daniel Nettle (Professor of Behavioural Science at Newcastle University) Location: via Zoom | Guests are welcome! Host: Max Planck Institute for the Study of Crime, Security and Law Contact: c.hillemanns@csl.mpg.de\nGreater socioeconomic inequality is associated with higher crime rates. If this association is causal, it is unclear how the population-level variable, inequality, affects decisions to offend in individuals’ heads. I will present a recent theoretical model in which individuals strive to remain their resources above a threshold of desperation that is set by their social context. Greater inequality means more individuals who are at or below this threshold. It becomes rational for them to offend as a risky strategy to leap clear of it. This produces a link between population-level inequality and individual decision-making. Moreover, we show that increasing punishment severity under these assumptions should not generally expected to reduce offending. I present a framework for studying the assumptions and predictions of the model in a multi-player incentivized economic game. Preliminary data are consistent with the predictions of the model. However, they are also consistent with simpler but still relevant hypotheses that do not use the assumption of a desperation threshold, such as that loss compared to some mental reference point leads to frustration and anger. We are currently attempting to test between these alternatives. We hope that the experimental framework, regardless of which way the results fall out, is useful for understanding antisocial motivations.", "pred_label": "__label__POS", "pred_score_pos": 0.9067919254302979} +{"content": "Abstract\nPulse density, the number of laser pulses that intercept a surface per unit area, is a key consideration when acquiring an Airborne Laser Scanning (ALS) dataset. This study compares area-based vegetation structure metrics derived from multireturn ALS simulated at six pulse densities (0.05 to 4 pl m-2) across a range of forest types: from savannah woodlands to dense rainforests. Results suggest that accurate measurement of structure metrics (canopy height, canopy cover, and vertical canopy structure) can be achieved with a pulse density of 0.5 pl m-2 across all forest types when compared to a dataset of 10 pl m-2. For pulse densities <0.5 pl m-2, two main sources of error lead to inaccuracies in estimation: the poor identification of the ground surface and sparse vegetation cover leading to under sampling of the canopy profile. This analysis provides useful information for land managers determining capture specifications for large-area ALS acquisitions.\nKeywords ITC-ISI-JOURNAL-ARTICLE", "pred_label": "__label__POS", "pred_score_pos": 0.9974815249443054} +{"content": "Can you test yourself for STDs at home?\nYou can check for STDs at home with the Everlywell STD test kit. This test screens for 6 common sexually transmitted infections, including chlamydia, gonorrhea, and HIV. It requires a simple urine sample collection and an easy finger-prick blood spot collection.\nHow do you know if you have an STD without getting tested?\nSome of the most common symptoms of STDs include the following:Changes in urination. Unusual discharge from the penis. Abnormal vaginal discharge or bleeding. Burning or itching in the vaginal area. Pain during sex. Bumps or sores. Pain in the pelvic or abdominal region. Nonspecific symptoms.\nHow do you test if you have STDs?\nHow Do Doctors Test for STDs?a blood sample (from either a blood draw or a finger prick)a urine sample.a swab of the inside of the mouth.a swab from the genitals, such as the urethra in guys or the cervix in girls.a swab of any discharge or sores.\nWhat are signs of an STD for a female?\nCommon symptoms of STIsChanges in urination. An STI can be indicated by pain or a burning sensation during urination, the need to pee more frequently, or the presence of blood in the urine.Abnormal vaginal discharge. Itching in the vaginal area. Pain during sex. Abnormal bleeding. Rashes or sores.", "pred_label": "__label__POS", "pred_score_pos": 0.7658641934394836} +{"content": "New research recently revealed that COVID-19 is not a respiratory illness but rather a vascular disease. This study, led by the University of California-San Diego, could explain blood clots in some patients and other issues, including “COVID feet,” which are not commonly experienced symptoms of respiratory disease.\nWhat’s your Reaction?", "pred_label": "__label__POS", "pred_score_pos": 0.9999906420707703} +{"content": "An investigation of the mechanisms of paradoxical atopic eczema in psoriasis patients treated with biologics\nBiologics are drugs targeting specific parts of the immune system and have transformed the therapeutic landscape for psoriasis. Approximately 2-5% of psoriasis patients on biologics for severe psoriasis experience a paradoxical disease phenotype switch to atopic eczema, which is an immunologically and genetically distinct disease. This can be devastating for patients, often necessitating treatment switches which are not always successful in controlling their psoriasis or resolving their eczema.\nThis research aims to establish the role of genetic factors in developing paradoxical atopic eczema and identify the changes that occur in the skin and immune system that drive this adverse event. This could improve treatment-selection for this group of patients and provide insight into the mechanisms of psoriasis and atopic eczema.\nWorking with Industry\nDr Al-Janabi is working UCB. He says:\n“Though I'm only in my second month of the fellowship, my industry partner, UCB , has been crucial. They contributed significantly to the study design, and several of the experiments would not be possible without their expertise. My industry supervisor has been particularly supportive as the study designs have had to develop, and the collaborative nature of this scheme has allowed me to appreciate the importance of industry in science and healthcare.”", "pred_label": "__label__POS", "pred_score_pos": 0.9737097024917603} +{"content": "Relationship between Personality Trait Introversion-Extroversion and Academic Achievement in Science Subjects among Secondary School Students in Tanzania Abstract\nWhile\nextrovert individuals tend to obtain their energy from other people, and they love talk, they interact, participate, lead, and socialize, introvert individuals direct their energy and attention inward and reflect on their own thoughts, memories, and feelings. Based on the introversion-extroversion personality characteristics, the present study sought to determine who performs better in science subjects between introverts and extroverts, and demonstrate these relationships by gender. The assumption was that while science classrooms require a great deal of interaction among the learners, these contrasting dimensions of personality trait could be reflected in classrooms and bear some implications on students’ learning and achievement. We employed a modified Eysenck Personality Questionnaire (EPQ) to identify students’ personality ( N=345) along introversion-extroversion scale and correlated these with their academic performance obtained from their National Form Two (Grade 9) Exam which is considered of high quality and standard. A comparison within sex revealed that introvert girls performed significantly better than extrovert girls whereas extrovert boys performed significantly better than introvert boys. When a comparison was made between sexes, it was revealed that extrovert boys had significantly higher grades compared to extrovert girls while introvert girls had significantly higher grades compared to introvert boys. Overall then, the study revealed a statistically significant correspondence of higher grades with introvert girls and extrovert boys, and lower grades with extrovert girls and introvert boys. The study implications and suggestions are made to inform instruction, guidance, and intervention. Full Text:PDF\nDOI: https://doi.org/10.5296/ijld.v11i3.18779\nRefbacks There are currently no refbacks.\nCopyright (c) 2021 Winston Edward Massam\nThis work is licensed under a Creative Commons Attribution 4.0 International License.", "pred_label": "__label__POS", "pred_score_pos": 0.9963331818580627} +{"content": "Pax1 and Pax9 synergistically regulate vertebral column development.The paralogous genes Pax1 and Pax9 constitute one group within the vertebrate Pax gene family. They encode closely related transcription factors and are expressed in similar patterns during mouse embryogenesis, suggesting that Pax1 and Pax9 act in similar developmental pathways. We have recently shown that mice homozygous for a defined Pax1 null allele exhibit morphological abnormalities of the axial skeleton, which is not affected in homozygous Pax9 mutants. To investigate a potential interaction of the two genes, we analysed Pax1/Pax9 double mutant mice. These mutants completely lack the medial derivatives of the sclerotomes, the vertebral bodies, intervertebral discs and the proximal parts of the ribs. This phenotype is much more severe than that of Pax1 single homozygous mutants. In contrast, the neural arches, which are derived from the lateral regions of the sclerotomes, are formed. The analysis of Pax9 expression in compound mutants indicates that both spatial expansion and upregulation of Pax9 expression account for its compensatory function during sclerotome development in the absence of Pax1. In Pax1/Pax9 double homozygous mutants, formation and anteroposterior polarity of sclerotomes, as well as induction of a chondrocyte-specific cell lineage, appear normal. However, instead of a segmental arrangement of vertebrae and intervertebral disc anlagen, a loose mesenchyme surrounding the notochord is formed. The gradual loss of Sox9 and Collagen II expression in this mesenchyme indicates that the sclerotomes are prevented from undergoing chondrogenesis. The first detectable defect is a low rate of cell proliferation in the ventromedial regions of the sclerotomes after sclerotome formation but before mesenchymal condensation normally occurs. At later stages, an increased number of cells undergoing apoptosis further reduces the area normally forming vertebrae and intervertebral discs. Our results reveal functional redundancy between Pax1 and Pax9 during vertebral column development and identify an early role of Pax1 and Pax9 in the control of cell proliferation during early sclerotome development. In addition, our data indicate that the development of medial and lateral elements of vertebrae is regulated by distinct genetic pathways.[1] References Pax1 and Pax9 synergistically regulate vertebral column development.Peters, H., Wilm, B., Sakai, N., Imai, K., Maas, R., Balling, R. Development(1999) [Pubmed]\nAnnotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg", "pred_label": "__label__POS", "pred_score_pos": 0.5930538177490234} +{"content": "The Fuwa Award is officially launched in 2021. The qualifications and criteria for the award are as follows.\n1. JADE has established the JADE Award in Development Economics in Memoryof Nobuhiko Fuwa (hereafter “Fuwa Award”) to remember the achievementsof late Professor Fuwa of the University of Tokyo, who passed away at hisyoung age of 56 while still making excellent research achievements in thefield of development economics. His notable contributions were on genderand poverty issues, including his pioneering work on impact evaluationsof conditional cash transfer programs for female students in Bangladesh,intra-household resource allocation in India, and poverty research in thePhilippines. The Fuwa Award is aimed to honor and support research of thosescholars who have made remarkable international research achievements inthese areas of development economics.\n2. The winner of the Fuwa Award should satisfy the following conditions.(1) A regular or student member at the time of winning the award.(2) Being affiliated or having been affiliated with a university, researchinstitution, or related organization in Japan and engaging in researchin development economics.(3) Having made internationally prominent research achievements in “thearea that contributes to improving social status of women in developingcountries.”\n3. The Fuwa Award is given once a year based on the past research achievements of the awardees, particularly the research publication in internationally reputable refereed journals. The establishment of the selection committee and the process of selections, including treatment and weighting of co-authorships, are determined by the JADE Board members. When these criteria are not satisfied by any of the candidates in a year, the Fuwa Award in that year is not awarded.\n4. The winner of the Fuwa Award is provided an honorable certificate and100,000yen.\n5. The Fuwa Award is supported by an anonymous donation givento JADE and is launched with a time limit of ten years.", "pred_label": "__label__POS", "pred_score_pos": 0.9527081251144409} +{"content": "In contrast to numerous previous reports that focused on the roles of IDH1 mutations in tumorigenesis (13,18C21), the present study was, to the best of our knowledge, the first study on the function of wild-type IDH1 in primary GBM cell migration. of phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway-regulated genes, including Myc, Bisoprolol Snail family transcriptional repressor 2 and Twist-related protein 1, which are primarily cell migration regulatory factors. Western blotting revealed that the overexpression or knockdown of IDH1 promoted or inhibited the PI3K/AKT/mTOR pathway, respectively. -KG treatment of primary GBM cells also promoted the PI3K/AKT/mTOR pathway. Furthermore, IDH1-overexpressing and -KG-treated U87 cells were incubated with rapamycin, an mTOR-specific inhibitor, and the results revealed that rapamycin treatment reversed the increased cell migration caused by IDH1 overexpression and -KG treatment. The results indicated that IDH1 regulated the migration of primary GBM cells by altering -KG levels and that the Bisoprolol function of the IDH1/-KG axis may rely on PI3K/AKT/mTOR pathway regulation. (15) reported that IDH1 suppression via shRNA or specific inhibitors inhibited primary GBM growth and facilitated cellular differentiation. However, the role of IDH1 in primary GBM cell migration remains elusive. Considering that primary GBM is a type of cancer that exhibits relatively high migratory abilities (27,28), excess IDH1 was hypothesized to contribute to primary GBM migration. The current Bisoprolol study discovered that IDH1 knockdown or overexpression led to repressed or improved cell migration, respectively. -KG is primarily produced by IDH1 via oxidative decarboxylation (38,39). Therefore, whether -KG mediated the effect of wild-type IDH1 on primary GBM cell migration was investigated. Cellular -KG levels were positively associated with changes in IDH1 levels. By treating U87 cells with different concentrations of -KG, dose-dependent increases in the migration rates of primary GBM cells were observed. However, to the best of our knowledge, there is no applicable method to directly reduce -KG levels in live cells, which impeded the current study to examine the effect of decreased -KG on cell migration. The most common way to reduce -KG levels in live cells is to repress enzymes that catalyze the production of -KG, such as IDH1. Therefore, the current study investigated the effect of IDH1 knockdown and the results matched expectations. Thus, the changes in the migration of primary GBM cells mediated by changes in IDH1 levels may occur by altering -KG levels. The PI3K/AKT/mTOR pathway regulates multiple cellular events, including growth, proliferation, motility and survival, which are often dysregulated in cancer (40). Although numerous previous studies (41C43) have reported the effect of the IDH1 R132H mutation on the PI3K/AKT/mTOR pathway, the correlation remains unclear. While IDH1 R132H and D-2HG were discovered to inhibit the PI3K/AKT/mTOR pathway in human glioma samples (41), another previous study reported that IDH1 R132H and 2-HG promoted the PI3K/AKT/mTOR pathway, resulting in upregulated glioma migration (44,45). Despite previous reports on mutated IDH1, the function of wild-type IDH1 and -KG levels on the PI3K/AKT/mTOR pathway remain unclear. The current study revealed that PI3K/AKT/mTOR pathway activity was enhanced by IDH1 overexpression and -KG treatment, and repressed by IDH1 knockdown. To further investigate whether the IDH1/-KG axis regulated primary GBM cell migration by modulating the PI3K/AKT/mTOR pathway, rapamycin treatment combined with IDH1 overexpression or -KG supplementation was employed. The results demonstrated that the increased cell migration of primary GBM cells was reversed, indicating that the IDH1/-KG axis regulated cell migration in primary GBM cells via the PI3K/AKT/mTOR pathway. Despite the mechanism revealed in the present study, there are areas of research that require further study. Firstly, as the results of the current study demonstrated that IDH1 may be a potential therapeutic target or diagnostic marker in primary GBM, further investigations are required prior to clinical application. Secondly, although -KG levels were reported to Rabbit Polyclonal to PGD regulate the PI3K/AKT/mTOR pathway in primary GBM cells, the detailed mechanism of.", "pred_label": "__label__POS", "pred_score_pos": 0.7233257293701172} +{"content": "The Australian Curriculum provides a powerful framework for supporting student-led, concept driven, transdisciplinary learning experiences that all students to access and engage in.\nOur teachers design purposefully connected curriculum units where our students engage with opportunities to address universal problems, and grow their understanding of our shared world without constraint of subject specific boundaries.\nTeachers plan a powerful provocation to hook students in, and get them thinking and asking questions about the big ideas. Classroom teachers and students explore a central conceptual idea and build broad enduring understandings that are significant, engaging and transferable to other contexts. Through this process, the subjects become one of their resources and ensure depth in their learning.\nThis approach, within the framework of the curriculum, encourages students to nurture their innate curiosity and take ownership of their learning. It also provides opportunities to explore their own questions and ignite their passion.\nThis connected curriculum approach supports our ultimate goal of ensuring our students become thriving, assessment capable learners who possess global competencies that empower them to influence and create a better world.", "pred_label": "__label__POS", "pred_score_pos": 0.9998027086257935} +{"content": "19 (1) A lessor may not require or accept a deposit or bond for pets that exceeds the equivalent of 1/2 of the monthly rent payable under the lease agreement. (i) the lessor has entered into a lease agreement beginning with the expiry of an existing lease involving the obligation to evacuate the rental unit with a new tenant for the rental unit, or (3) The manager may not extend the dispute resolution request period to contest a termination of the lease beyond the effective date of termination. A deposit (often called a deposit) is the money that the owner collects at the beginning of the rental and holds until the extract. (e) personal property confiscated or received by a lessor must be returned, contrary to the law or the rental contract; A lease is a good quality contract between you and the owner that defines the conditions of the rented property. When we talk about a lease, we most often refer to a written document, but a lease can also be oral. At the end of your rental, your landlord may try to use your deposit to pay for the damaged unit. You want to make sure that you clearly document the condition of the unit before moving in, so the landlord can`t blame you for damages that weren`t your fault. (3) A lessor who is a natural person may terminate a lease in relation to a rental unit if the lessor or a close family member of the lessor intends to occupy the rental unit in good faith. Owners of prefabricated parks must use this form to terminate the lease if they wish to convert all or a substantial part of the park for other purposes. Tenants who prematurely terminate a temporary tenancy contract due to domestic violence or long-term care must provide the landlord with a copy of this form, completed by a legitimate third party. 45.3 In the event of a breach of a fixed-term rental agreement in accordance with point 45.1 [tenant`s decision: domestic violence or long-term care] by one in two or more tenants subject to the same rental agreement, the remaining tenant or tenant must also: the rental apartment is cleared, unless the remaining tenant or the remaining tenants enter into a new lease with the lessor. (2.1) Subsection (2) (a.1) of this Division does not apply if the right is based on the fact that a statement purporting to confirm a tenant`s authorization to terminate a temporary lease within the meaning of subsection 45.1 (2) was made by a person who did not have the authority to do so under the rules.\n(3) If the lessor and the lessee have not entered into a new lease by the end date of a fixed-term lease, which does not require the lessee to evacuate the rental unit by that date, the lessor and the lessee shall be deemed to be renewed as a monthly lease on equal terms. A monthly lease does not have a predetermined date on which it ends. The rental agreement continues until the tenant correctly indicates the extract or until the lessor legally terminates the lease. . . .", "pred_label": "__label__POS", "pred_score_pos": 0.9138673543930054} +{"content": "Accession Number: ADA280575 Title: Expanding Our Vision of Jointness: Pursuing Joint Force Developmental Strategies Descriptive Note: Final rept. Corporate Author: AIR WAR COLL MAXWELL AFB AL Personal Author(s): Report Date: 1994-01-01 Pagination or Media Count: 37.0 Abstract:\nAmidst the tumultuous environment of the last decade, the U.S. military has made significant progress towards jointness following the impetus from operational experiences in Vietnam, Desert 1, and Grenada and Congressional prodding via the 1986 Goldwater-Nichols Act. However, that progress has primarily occurred in the force employment component of military strategy and at the operational art level and below. By comparison, little attention or emphasis has been placed on jointness in the force developmental component of military strategy. This paper will examine some of the reasons for that nearsightedness, explore the resulting national security implications, and pose broad, conceptual approaches to extend jointness across the full spectrum of national security and military strategy considerations. Specifically, the paper will advocate a broader application of joint strategy to enable planners to manage uncertainty, integrate diverse capabilities and better retain military power with decidedly smaller forces. The gist of these proposed practices is a greater, reinvigorated commitment to an axiom of strategy guiding planning, leading action.\nDescriptors: Subject Categories: Military Operations, Strategy and Tactics", "pred_label": "__label__POS", "pred_score_pos": 0.8670765161514282} +{"content": "In a landmark decision Wednesday, a Brisbane court ruled the levy - dubbed the \"backpacker tax\" - can not be applied to a British woman due to a double taxation treaty between Australia and the UK.\nIt means backpackers would be entitled to a tax-free threshold of $18,200 like any other Australian citizen.\nJudge Logan called these parallel rates of income tax \"a disguised form of discrimination based on nationality\" that is explicitly prohibited in the taxation agreements between Australia and the eight nations in question.\nIf this amount was paid to the 80,000 working tourists in Oz, the government could face a bill of AU$176 million (£93,806,240). In contrast, foreign workers on 417 or 462 visas are taxed 15% on the first $37,000 they earn.\nBut the AU$18,200 tax exemption should still apply to anyone living at a permanent address, regardless of their citizenship, as they are classed as residents for tax purposes.\nMs Addy mainly lived in a\nSydney sharehouse and stayed, for the most part, in New South Wales - meaning she was considered a \"resident\" for tax purposes.\nWhile the UK's tax deal with Australia includes a commitment not to impose \"more burdensome\" rates on its citizens resident there, Ireland's tax deal with Australia omits this specific protection.\n3 World Series Contenders Nobody is Talking About\nDespite being loaded on offense, the Cardinals have been inefficient in 2019 and rank near the bottom-10 in runs and home runs. Louis has title-winning pedigree and are loaded offensively, but thus far simply haven’t delivered consistent results.\nThe federal court in Australia has ruled that the so-called \"backpacker tax\" could not be levied against some backpackers because it violated pre-existing agreements with some countries.\n\"It also damaged Australia's reputation as a working holiday destination\", Joanna Murphy, the firm's CEO, said.\n'In the context of these working holidaymakers, this is a really significant judgement'.\nAustralian broadcaster ABC said an estimated 75,000 foreign nationals could receive hundreds of millions of dollars from the Australian Tax Office (ATO).\n\"We're delighted the Court has accepted our argument and we look forward to the Australian Government restoring the previous - fairer and non-discriminatory - taxation arrangements that apply to holiday workers\", she said.\nWhile this initial ruling does not affect Irish people on working holiday visas, Taxback.com, who organised the lawsuit, believe it could have a knock-on effect in the future.\nHowever, this interpretation is likely to also face challenge, based on another of Logan's recent rulings in which he said a backpacker who meant to move to Australia for 10 months, and does so, would become a resident for tax purposes.", "pred_label": "__label__POS", "pred_score_pos": 0.9171516299247742} +{"content": "Indian Environmental Law: Key Concepts and Principles\nFor more than three decades now, the Indian courts have delivered far-reaching judgments on a range of significant environmental matters. In their effort to adjudicate complex disputes with serious environmental repercussions, involving the interplay of multiple social, economic and political factors, the courts have developed a framework of environmental rights and legal principles, which now forms an integral part of Indian environmental jurisprudence. The judiciary invokes this framework creatively to identify constitutional, statutory and common law obligations of public and private actors to protect the environment, and to enforce the performance of related duties. There is, however, limited in-depth study of these crucial rights and principles in existing legal literature.\nIndian Environmental Law: Key Concepts and Principles fills this gap through its critical analysis of the evolution of this environmental legal framework in India. It studies the origins of environmental rights, substantive and procedural, and the four most significant legal principles- principle of sustainable development, polluter pays principle, precautionary principle and the public trust doctrine-and elaborates how Indian courts have defined, interpreted and applied them across a range of contexts.\nAs environmental litigation and legal adjudication struggle to respond to this crisis, conceptual clarity about the content, application and limitations of environmental rights and legal principles is crucial for the improvement of environmental governance. This book explores the judicial reasoning and underlying assumptions in landmark judgments of the Supreme Court, the High Courts and the National Green Tribunal, and aims to provide the reader with a comprehensive understanding of this framework of rights and principles.\nContents: Foreword by Pratap Bhanu Mehta. Introduction. Part I: 1. The judiciary and the right to environment in India: past, present and future/Lovleen Bhullar. 2. Procedural environmental rights in Indian law/Shibani Ghosh. Part II: 3. Sustainable development and Indian environmental jurisprudence/Saptarishi Bandopadhyay. 4. The polluter pays principle: scope and limits of judicial decisions/Lovleen Bhullar. 5. The precautionary principle/Lavanya Rajamani. 6. Public trust doctrine in indian environmental law/Shibani Ghosh. 7. The judicial implementation of environmental law in India/Dhvani Mehta. Notes on the contributors. Index.\n55.80 50.22 $62.00 $ Get it now and save 10%\nBECOME A MEMBER\n36.00Add to cart $40.00 $ 19.80Add to cart $22.00 $ 35.10Add to cart $39.00 $ 90.00Add to cart $100.00 $", "pred_label": "__label__POS", "pred_score_pos": 0.9360843300819397} +{"content": "Road traffic and railway noise exposures and adiposity in adults: A cross-sectional analysis of the Danish diet, cancer, and health cohort\nTraffic noise has been associated with cardiovascular and metabolic disorders. Potential modes of action are through stress and sleep disturbance, which may lead to endocrine dysregulation and overweight. The researchers aimed to investigate the relationship between residential traffic and railway noise and adiposity.", "pred_label": "__label__POS", "pred_score_pos": 0.6440225839614868} +{"content": "Abstract\nAims: To investigate the relative role of the red dry and rough (rdar) and brown dry and rough (bdar) morphotypes on hydrophobicity and ability to attach to abiotic surfaces of poultry-associated Salmonella strains with a focus on S. Sofia. Methods and Results: Cellulose synthase gene null mutants were constructed in five Salmonella strains converting them from rdar to bdar morphotypes. One S. Sofia null mutant displayed reduced hydrophobicity and attachment to Teflon (R) relative to its parent strain. The S. Virchow and S. Infantis null mutants attached less well to glass relative to their parent strains. Conclusions: The rdar or bdar morphotype may influence S. Sofia persistence but did not explain why bdar strains predominate in this serotype. Significance and Impact of the Study: This work provides some insight into why some Salmonella strains survive in poultry environments and may ultimately contribute to their control.", "pred_label": "__label__POS", "pred_score_pos": 0.6030899286270142} +{"content": "This fall, the\nwelcomes Federal Reserve Board Governor Michelle Bowman, who will visit SDSU on October 13 Dykhouse Program Speakers Series thto speak on making monetary policy and the outlook for the U.S economy. Governor Bowman is one of six sitting members of the Federal Reserve Board of Governors.\nAs the nation’s central bank, the Federal Reserve System is charged by Congress with a dual mandate to promote maximum employment and stable prices in the U.S. economy. The system’s Federal Open Market Committee (FOMC) achieves this mandate by influencing interest rates and financial conditions more generally. As a member of the Board of Governors and the FOMC, Governor Michelle Bowman plays an integral role in shaping U.S. monetary policy, which remains historically loose in the wake of the pandemic and the economic disruptions it has imposed on us all. On the evening of October 13\nth, Governor Bowman will share her perspective on the paths of U.S. monetary policy and economic performance going forward.\nThe event will be held at 7 pm in the Larson Memorial Concert Hall of our Performing Arts Center. The event is free, and no registration is necessary.", "pred_label": "__label__POS", "pred_score_pos": 0.7094812989234924} +{"content": "Omnichannel solutions allow businesses to reach a broad range of customers and provide them with an engaging, consistent message.\nNot only does an omnichannel strategy enable you to reach a larger audience, but it also lets your business provide consistent messages across multiple platforms.\nBy meeting your audience's needs and allowing customers to engage with your brand wherever they choose, a multi-channel approach will enable you to keep up with today's on-the-go users.\nAs each channel works complementary with each other, you can learn more about your audience and gain insights that wouldn't be possible through a single channel alone.Contact Us\nIncrease customer loyalty and reinforce brand recognition across multiple channels in various ways. Engage your customer through highly targeted marketing campaigns that build consumer trust and customer satisfaction.\nBy employing a unified marketing strategy, you can accurately track and monitor how your customers interact and engage with your content, allowing you to optimize for success across all channels.\nUnify your marketing efforts and interact with your customers consistently through various channels such as SMS, email, mobile, and social media as well as your site and the marketplaces you sell on.\nProviding multiple touch-points across the buyer's journey through consistent messaging, information, and imagery not only improves brand recall but also allows you to personalize the shopping experience while giving your customer the option to purchase from the channel they prefer most.Contact Us\nAccommodate your customers with a seamless-content rich user experience by serving them where they are. With our team of marketing specialists, reach your sales targets faster and achieve higher lifetime customer values through an integrated, data-driven, strategic approach.\nAs the path to purchase is ever-evolving, omnichannel marketing allows you to tailor the marketing process to deliver the ultimate customer experience and build lasting relationships with your audience.", "pred_label": "__label__POS", "pred_score_pos": 0.9878038167953491} +{"content": "Rise with SAP – How Fingent Can Help Explore Business Transformation as a Service (BTaaS)\nIn the current circumstances where industries are experiencing periods of intense change, organizations need a new paradigm. They need a product that must be capable of reframing the problems which were addressed by previous solutions or that targets a new set of problems. They also need a partner who can effectively deploy the solution and provide assistance whenever there is a need. SAP created a solution that addresses a set of existing problems through the method of reframing them, thereby presenting a novel way of addressing these issues in the form of BTaaS-Rise with SAP. Rise with SAP helps enterprises gain digital efficiency and flexibility.\nDo you feel this pathway to intelligence is formidable and elusive? If so, rest assured that we, at Fingent, understand the challenge you face. This blog will help you understand what the benefits of the initiative are, how we approach it, and how we can help you deploy these services.\nWhat is BTaaS-Rise with SAP\nBTaaS (Business Transformation as a service) Rise with SAP is a suite of services and products. It is designed to accelerate the transformation into creating an intelligent enterprise. It is a direct response to the challenges in the steady acceleration of change in all areas of business.\nAs BTaaS, Rise with SAP can help businesses remain resilient and adapt to digital transformation quickly despite cutthroat competition in their respective industries. It offers these five components to build an Intelligent Enterprise:\nTechnical Migration tools and services S/4 HANA cloud SAP business technology platform Business process intelligence SAP business network starter pack How Can Your Business Benefit from Rise with SAP?\nRise with SAP allows you to be in control. You can choose where to begin your journey and you can design a suitable strategy that fits your business.\nLet us now examine the twofold benefit of Rise with SAP:\nValue from differentiating business capabilities and outcomes\nThis value has a significant impact on shareholder returns. This impact ensures long-term sustainability with purpose. Here are the top three benefits for your business:\nTop line:This includes your strategy, employees, and your products. You can improve your top line by innovating and establishing new revenue streams and business processes. Bottom line:You can improve operational efficiencies by eliminating repetitive tasks. You can save time and resources by allowing intelligent ERP to function as a co-pilot providing you with suggestions based on business process patterns and employee behavior. Green line:Rise with SAP will help you understand, monitor, and optimize environmental and social impact throughout the value chain. This will help minimize wastage, improve safety, build supplier compliance, and attain resiliency. Value-driven from cloud delivery capabilities\nThis is essentially the incremental value. It allows enterprises to maximize value, minimize transformation risk, and reduce cost to the extent possible. Explore the top three benefits for your business:\nFacilitates process excellence:Using process discovery reports, migration tools, and services and other capabilities your enterprise becomes transformation ready. Improved service experience:Rise with SAP is a Business Transformation as a service; a simpler support model. Thus, you have the benefit of an improved service experience. Operational resiliency:You can hyperscale infrastructure with inbuilt full-stack security. Lower TCO:It allows you to use flexible user-based subscriptions and leverage hyperscale economics to lower TCO.\nBut what do you need to gain these capabilities? Well, you need these three things:\nTechnology that can support your company processes A cloud provider A capable and efficient partner who can help you take greater advantage of Rise with SAP Role Of Fingent in Leveraging These Services\nFingent is geared to work with enterprises under the framework of Rise with SAP. As SAP’s Silver Partner, we have a credible background in helping enterprises uncover business inefficiencies and redesign their processes to fit their needs. With deep domain expertise, we help them align and achieve organizational goals at optimal costs.\nWe understand the difficulties some organizations face in making decisions with regard to business transformation. Our program is designed precisely for such organizations. As a trusted Silver Partner, Fingent is here to guide you through every step of this exercise.\nWe start by developing a deep understanding of your business and your objectives. We then use our expertise in SAP to devise a strategy for a comprehensive business transformation strategy. As a seasoned SAP Silver Partner, Fingent combines its expertise with a deep understanding of user experience to maximize your operational efficiency.\nOur approach can analyze complexities around your business processes and adopt a user-first approach. This can drive a successful implementation of Rise with SAP that leads to increased user adoption.\nAs suggested by Rise with SAP program, our engagement starts with a process and system audit. This will form the backbone for subsequent phases of the transformation process. Fingent will be with you at every step. We work with your business leadership, key stakeholders. We involve key influences to ensure the successful completion of your business transformation.\nWe Can Help Your Business RISE!\nRise with SAP is another possibility for us to empower clients with the help of the SAP portfolio. In close coordination with SAP, we create tailor-made solutions that increase the value of this initiative for you.\nTo do this, we combine SAP capabilities with products and services that we have developed ourselves to individualize for your specific needs. This is how we at Fingent ensure that you receive a truly customized solution – one that addresses specific challenges in your specific environment. This will generate the best possible value for your business.\nYou can rely on us as your sole contractual partner and thus avoid needless complexities. We offer everything from advisory services to application management. All this can be done at your own pace, with your budget, and according to your business needs.\nWe can smoothen the path of transformation for our existing customers. For our new customers, we can leverage the full potential of Rise with SAP and customize it for your advantage.\nTalk to our experts at Fingent and together we will find ways to make the best out of Rise with SAP for you!", "pred_label": "__label__POS", "pred_score_pos": 0.6984091997146606} +{"content": "A new model from the Centers for Disease Control and Prevention (CDC) predicts COVID-19 deaths and hospitalizations will continue to decline over t\nA new model from the Centers for Disease Control and Prevention (CDC) predicts COVID-19 deaths and hospitalizations will continue to decline over the next month.\nPublished on Wednesday, the ‘ensemble’ forecast combines 37 independent forecasts of coronavirus deaths over the next four weeks into one projection.\nThe CDC projects that weekly Covid fatalities could fall to fewer than 4,000 by the week ending November 6.\nOver the same time period, hospitalizations are predicted to drop to as few as 500 per week.\nIt comes as infections across the U.S. continue to decline and the fourth wave of the pandemic, fueled by the Delta variant, comes to an end.\nA new CDC ensemble forecast projects COVID-19 deaths and hospitalizations in the U.S. will continue to decline. Pictured: Bodies are moved to a refrigeration truck serving as a temporary morgue at Wyckoff Hospital in Brooklyn, New York, April 2020\nThe forecast predicts weekly deaths will fall to as low as 3,900 by the week ending November 6 from the current 12,100 per week (above)\nOn Wednesday, the U.S. recorded 3,054 virus-related deaths and a seven-day rolling average of 1,657, according to data from Johns Hopkins University.\nThis represents a 13 percent decrease from the 1,917 average deaths recorded on month ago.\nThe CDC expects this decline to continue into November.\nAccording to the forecast, deaths are expect to decline over the next four week with between 3,900 and 13,100 new weekly deaths reported by by November 6, 2021, the third straight week of projected declines.\nAdditionally, the forecast predicts a death toll of between 740,000 and 762,000 by the first week of November\nCurrently, there have been more than 717,000 Covid deaths since the pandemic began, figures from Johns Hopkins show.\nThe hospitalization model, made from an ensemble of six independent forecasts, are also expected to drop.\nThe CDC model suggests that between 500 new hospitalizations per week to 10,100 new hospitalizations per week will be reported by November 5, the fifth week of predicted declines.\nAs of Wednesday, 62,132 patients are currently hospitalized due to COVID-19, according to the Department of Health and Human Services (HHS).\nIt’s a drop of 33 percent from the 93,703 hospitalizations recorded four weeks ago.\nCovid hospitalizations are also predicted to drop to as few as 500 new patients admitted per week, a fifth straight week of projected declines (above\nThe CDC’s model is not the only forecast that has predicted deaths will decline.\nAnother analysis, conducted by the COVID-19 Scenario Modeling Hub, which advises the CDC, was published last month and looked at different scenarios regarding the trajectory of the pandemic.\nResearchers came up with four different scenarios depending on whether or not children between ages five and 11 are authorized to get vaccinated and whether or not a new variant starts spreading.\nThe model does not advocate for or against childhood vaccinations, but merely suggests they will begin occurring by fall 2021.\nBEST CASE SCENARIO FOR DEATHS: Deaths are also projected to drop from 11,563 current weekly deaths, or 1,651 per day, to 415 weekly fatalities, or about 59 per day (above)\nWORST CASE SCENARIO FOR DEATHS: Weekly deaths would also have a modest drop to 4,922, or 703 daily deaths by March 2022 (above)\nAccording to the model, this will result in weekly COVID-19 deaths declining to 415 weekly fatalities, or about 59 per day.\nThese are figures not seen since late March 2020, when states first began shutting down and implementing stay-at-home orders.\nIn the worst case scenario, in which children aren’t approved for vaccination and a new variant that is 1.5 times more transmissible starts circulating, cases and deaths would still decline – but not by as much.\nThe model predicts this scenario would led to weekly cases falling to 467,507, or 66,786 daily infections, and 4,922 weekly deaths, or 703 daily deaths by next spring.\nThese numbers are similar to levels that were seen during summer 2020, amid the second wave of the pandemic, and in April 2021, following the deadly third wave.", "pred_label": "__label__POS", "pred_score_pos": 0.5184244513511658} +{"content": "Resources\nThis fact sheet provides references to technical assistance providers to support grantees as they strive to target results and indicators in the PN grant. It provides contact information, organizational descriptions, and other relevant services and resources.\nThis resource provides a grantee spotlight on Berea College in a series of videos that highlights PNs' work to target the cradle-to-career pipeline in improving student and family outcomes. This video focuses on Berea College's strong early childhood segment of the pipeline.\nThis report provides a guide to demonstrate early learning results and identify challenges and lessons learned for three Promise Neighborhoods: Berea College, Hayward, and the Northside Achievement Zone. Focuses on the 10 results and 15 indicators, and how to target the cradle to career pipeline\nIn this presentation, former Secretary Arne Duncan makes remarks at the Harlem Children's Zone Conference and discusses Harlem Children's Zone and other examples that would fit the Promise Neighborhood model.\nThis fact sheet is a series of talking points to promote the continued support for Promise Neighborhoods. It addresses federal funding, reasons for continued investment, and information about the impact of PN efforts.\nThis is an example fact sheet for sharing impact of the PN with funders and partners.\nThis report discusses issues for understanding a comprehensive evaluation of performance and impact of PN grantees. It provides insight from the perspective of organizations working with evaluation and practice and who hope to improve outcomes for children and families.\nCommunity of Practice: Turning the Curve on Early Childhood Indicators and Early Lessons Learned about Implementation\nThis presentation focuses on using data and results-based framework to impact early childhoor indicators in PNs. It addresses the 10 PN results and how to work on these areas through the Results-Based Accountability structure.\nThis report recommends 21 results and accompanying indicators for Promise Neighborhoods. The authors detail existing key data sources, results, and suggested indicators focused on improving health, development, and education of children.\nThis fact sheet provides criteria and guidelines for building effective data systems. The authors assert that comprehensive data systems are essential for efficacious PNs to collect and organize data and inform decisionmaking.", "pred_label": "__label__POS", "pred_score_pos": 0.619464099407196} +{"content": "Different methods have been applied in controlling contamination of foods and feeds by the carcinogenic fungaltoxin, aflatoxin, but nevertheless the problem remains pervasive in developing countries. Curcumin is a naturalpolyphenolic compound from the spice turmeric (Curcuma longa L.) that has been identified as an efficientphotosensitiser for inactivation of Aspergillus flavus conidia. Curcumin mediated photoinactivation of A. flavushas revealed the potential of this technology to be an effective method for reducing population density of theaflatoxin-producing fungus in foods. This study demonstrates the influence of pH and temperature on efficiencyof photoinactivation of the fungus and how treating spore-contaminated maize kernels affects aflatoxin pro duction. The results show the efficiency of curcumin mediated photoinactivation of fungal conidia and hyphaewere not affected by temperatures between 15 and 35 °C or pH range of 1.5–9.0. The production of aflatoxin B1was significantly lower (p < 0.05), with an average of 82.4 μg/kg as compared to up to 305.9 μg/kg observed inuntreated maize kept under similar conditions. The results of this study indicate that curcumin mediated pho tosensitization can potentially be applied under simple environmental conditions to achieve significant reduc tion of post-harvest contamination of aflatoxin B1 in maize.", "pred_label": "__label__POS", "pred_score_pos": 0.9329918622970581} +{"content": "Prepare a 15- to 20-slide Microsoft® PowerPoint® presentation that details your chosen health issue and proposed health promotion idea. In your presentation: Describe the demographics of our current aging population.Include demographics specific to your proposed clientele.Describe the leading diseases and high-risk behaviors among the older population.Include statistics.Explain why you chose to address your particular health issue.Detail your health promotion idea. Include:How is it similar to or different than other available programs?How is it supported by theories on aging?How it supports the changes taking place in the booming aging population?What role does it play within the health care continuum?How can you use innovative technology to support and retain aging independence?What the program might look like logistically?Consider factors like costs, funding, time and personnel needed, location, resources, and promotion. Include detailed speaker notes of 100 words per slide. Use a minimum of 5 references to support your presentation. Create a one-page handout to accompany your presentation. Format your assignment according to APA guidelines.", "pred_label": "__label__POS", "pred_score_pos": 0.995016872882843} +{"content": "Our solution includes innovative cable system design and engineering, qualification testing and manufacturing, cable-laying and installation. This includes challenging trenching and rock dumping in a rough environment, as well as the successful commissioning.\nThe high-voltage cable system connects the Goliat platform to the onshore power grid via a three-core static AC cable that runs 105 km along the seabed. A 1.5 km dynamic AC cable connects the platform to the static AC cable, 350 meters below the surface.\nWe extend technical boundaries with this dynamic AC power-from-shore cable system. The 75 MW rating of the cable allows for an increase in energy supply if Eni Norge one day would want to power additional fields from the same system. The dynamic cable section, which weighs 90 kg per meter and hangs in the water between the platform and the seabed, withstands severe mechanical stress from currents, waves and the continuous movement of the platform.\nAn important feature of our solution is the innovative corrugated copper sheath that is designed to operate for the full production lifetime of the Goliat field in the extreme, high-stress conditions.\nNKT’s high-voltage XLPE submarine cables have low electrical losses. They are resistant to solvents, oil and abrasions, and have an excellent tensile strength. Our technology is truly ideal for harsh marine environments.", "pred_label": "__label__POS", "pred_score_pos": 0.8321130275726318} +{"content": "Talking about Legacies and Ruptures: Generational Narratives in Times of Youth Activism in Argentina and Chile Abstract\nThis article explores how generational narratives have emerged in the process of democratization in two post-authoritarian countries. Recent youth activism in Argentina and Chile provides fertile ground for the exploration of different generational narratives circulating amongst those born in the aftermath of transitions to democracy. In both countries, youths’ generational sites are characterized by strong political mobilization and by dynamics of collectively remembering right-wing dictatorships (in Argentina, from 1976 to 1983; in Chile, from 1973 to 1989). The linkage of difficult pasts with cycles of youth mobilization particularly deserves attention. While youth activism in Argentina is narrated from an intergenerational standpoint, Chilean student protests have been framed around a generational breakpoint. The article aims to answer why these different narratives of legacy and rupture emerged in these two contexts.\nBased on the literature about generations within memory studies and cultural sociology, a narrative approach for examining generational memories is proposed, and then applied to understand Argentinean and Chilean youths’ generational sites.", "pred_label": "__label__POS", "pred_score_pos": 0.9156509637832642} +{"content": "Ecological Benefits of Reduced Hydrologic Connectivity in Intensively Developed Landscapes\nA broad perspective on hydrologic connectivity is necessary when managing stream ecosystems and establishing conservation priorities. Hydrologic connectivity refers to the water-mediated transport of matter, energy, or organisms within or between elements of the hydrologic cycle. The potential negative consequences of enhancing hydrologic connectivity warrant careful consideration in human-modified landscapes that are increasingly characterized by hydrologic alteration, exotic species, high levels of nutrients and toxins, and disturbed sediment regimes. While connectivity is integral to the structure and function of aquatic ecosystems, it can also promote the distribution of undesirable components. Here we provide examples illustrating how reduced hydrologic connectivity can provide greater ecological benefits than enhanced connectivity does in highly developed, human-modified ecosystems; for example, in urban landscapes, ‚Äúrestoration‚ÄĚ efforts can sometimes create population sinks for endangered biota. We conclude by emphasizing the importance of adaptive management and balancing trade-offs associated with further alterations of hydrologic connectivity in human-modified landscapes.", "pred_label": "__label__POS", "pred_score_pos": 0.5929111242294312} +{"content": "CompAir offers an ideal solution with a comprehensive range of cost effective nitrogen generator systems from compressed air, that enable users to produce their total demand for nitrogen gas on their premises and under their control.\nCompared to traditional methods of supply, on-site nitrogen generator is exceptionally cost-efficient with a short payback time on investment - in many cases less than twelve months.\nNitrogen is used for a wide range of industrial applications including atmosphere packaging for perishable food products. It is also used in preventing fire and explosions in chemical plants. Using high quality compressed air to supply the generators, ensures long and trouble-free service and guarantees optimum performance.\nCompAir has a comprehensive range of systems that include everything needed to set up an on-site nitrogen generation system. CompAir air compressors and pre-treatment packages include adsorption dryers and coalescing filters to guarantee the highest quality air supply for the generators. The gas can be produced from your existing system with a minimum of additional floor space.\nTypical gas supply methods include high pressure cylinders, liquid mini tanks or bulk storage vessels. A CompAir generator makes the workplace considerably safer for employees, eliminating the safety risks associated with traditional methods. When compared to outsourced supplies, on-site nitrogen generation offers a greater flexibility and has a significant impact on time and costs.\nAir Treatment & Accessories\nQuality Air compressor Spare Parts", "pred_label": "__label__POS", "pred_score_pos": 0.9763758778572083} +{"content": "The Insolvency and Bankruptcy Board of India has consistently strived to amend and strengthen the Code since it was enforced in 2016. In light of all these changes, to further strengthen the Code, the Board has come out with new notifications for the (Fourth Amendment) Regulations. The amendment will directly have an impact on Operational Creditors and will also address the relation of the quantum of their dues.\nThe Amendment states that Sub-regulation 38(1) of the Regulations stands replaced by the following clause: “\nThe amount due to the operational creditors under a resolution plan shall be given priority in payment over financial creditors.” The earlier Regulation 38(1)\nOriginally, Regulation 38(1) stated that a resolution plan will mandatorily provide the source of funds for the liquidation value due to operational creditors. It then provided that;\nsuch liquidation value ought to be paid in priority to payments to any financial creditor; and such payment has to be made within 30 days from the approval of the resolution plan by the adjudicating authority.\nAs was the interpretation, it regulated that the liquidation value was the bare minimum which had to be paid to operational creditors under the resolution plan and within 30 days from the approval of the resolution plan. It further stated that payments could be made to operational creditors though the same were not mandatory neither were they priority.\nThe Amendment\nThe new amended Regulation states that a resolution plan should mandatorily provide the due amount to operational creditors. Under a resolution plan, the operation creditor will be given priority in payment over financial creditors.\nThere is no minimum amount prescribed for payment to operational creditors under the amended Regulations though sub-section 30 (2)(b) of the Code requires the resolution professional to confirm that the resolution plan provides for the payment of debts of operational creditors which should not be less than the amount to be paid to the operational creditors in the event of a liquidation of the corporate debtor under Section 53 of the Code. Therefore, the minimum prescribed amount due to operational creditors remains unchanged and the interests of operational creditors, to the extent of the liquidation value of the amount due to them, remain protected under the Code.\nThe primarily change brought by the Amendment is all payments due to operational creditors as contemplated under a resolution plan, and not just the minimum prescribed amount, have to be made in priority to financial creditors.\nWhat are the implications?\nAs operational creditors are not part of Committee of Creditors (CoC), the quantum of their dues which are payable under a resolution plan and have been prioritised, is still subject to the approval of only the CoC.\nIt is important to note that since CoC is under no fiduciary duty to act in the best interest of stakeholders which also includes operational creditors, this may be a tricky situation. Further, there is no provision which statutorily permits NCLT to reject a resolution plan only on the basis of inequity or discrimination under a particular class of stakeholders.\nShould the CoC rule against Operational Creditors, they can proceed to NCLT and file in the tribunals for some relief. All payments to operational creditors are prioritized and are now stated to be made before any payment is made to financial creditors can lead to a series of doubts and unfair cut-outs by the CoC.\nEven though the Board has been constantly trying to strengthen the Code, the onground reality of the amendments will be clear once the notification is in effect.", "pred_label": "__label__POS", "pred_score_pos": 0.8845585584640503} +{"content": "Glaciers in Washington state have gone through the most severe and rapid melting episode of the last 100 years, scientists say\nShocking aerial images taken from above Mount Rainier revealed the sparse covering of snow left on the iconic mountain as Washington state, along with 33 others, braces for more extreme heatwave conditions.\nThe lack of snow is linked to the deadly heatwave which descended on the Pacific Northwest earlier in the summer.\nDr Samuel Browd, who was on a flight that passed Mt Rainier earlier this week, tweeted a photo of the snow loss. “Striking the reduction in snowpack and glaciers. #ClimateEmergency is real,” he noted.\nAccording to scientists at Washington State University, the glaciers in the state have gone through the most severe and rapid melting episode of the last 100 years.\nHeatwaves across the US are expected to continue well into August. Some 200 million people are under heat advisories as two heat domes are lodged over states in the Pacific Northwest, the upper Midwest, and on the East Coast.\nOn Thursday, it reached 97 degrees Fahrenheit in Washington DC, the hottest temperature in the US.\nExtreme heat can have dire consequences. Earlier this summer, nearly 200 people died from a record-breaking heatwave which struck in Washington, Oregon and parts of western Canada. Hundreds of excess deaths in all three areas may also be linked to the heat.\n“Extreme heat and humidity will significantly increase the potential for heat-related illnesses, particularly for those working or participating in outdoor activities,” the National Weather Service on Wednesday.\nHeatwaves can also worsen wildfire conditions. The Dixie Fire, which has been raging in northern California for the past month, has been exacerbated by high temperatures. The blaze has grown to half a million acres and is only 30 per cent contained.\nA report released on Monday from the IPCC, the world’s leading body on climate science, noted that the climate crisis is causing more frequent and intense heatwaves, and that “unprecedented” heat events will continue as global temperatures continue to rise.\nWhile temperatures will eventually cool off in the Pacific Northwest and the east coast in the fall, droughts on west will cause more heatwaves to occur more frequently.", "pred_label": "__label__POS", "pred_score_pos": 0.5879673957824707} +{"content": "This report looks at the progress since Mayor de Blasio’s overhaul of Build It Back, the impact of the recommendations outlined in One City Rebuilding Together, and the City’s plans to complete the Build It Back program.\nThe city’s diminishing stock of rent-stabilized apartments is highly sought after by prospective tenants because these regulated units often rent at below-market rates and offer a variety of tenant protections including the right to lease renewal.", "pred_label": "__label__POS", "pred_score_pos": 0.9942173957824707} +{"content": "Corporations, universities, and individuals have tried to find some magic formula to understand personalities and what characteristics and skills someone brings to the table. Over the years and across the globe, people have used handwriting analysis, phrenology—reading the bumps on the head, and even Ivy League diplomas to ascertain if someone has leadership potential or is an ideal team player. Perhaps the best known personality test is the Myers-Briggs Type Indicator. This episode takes a deep dive into the skeptical side of this topic with Dan McAdams, a professor of psychology at Northwestern University.", "pred_label": "__label__POS", "pred_score_pos": 0.8504263162612915} +{"content": "Abstract\nEnvironmental predictors select individuals by their functional traits, shaping the anuran assembly patterns. Individuals respond to environmental filters that can be on a local or regional scale.\nIn this study, we investigated the association between local (water and microhabitat) and landscape variables and the morphological traits of tadpoles of ponds and streams. The study was conducted in the southern region of the Brazilian Atlantic Forest. We sampled 28 waterbodies and recorded 22 anurans species. We performed RLQ and fourth-corner analyses to determine the patterns of trait-environment relationships and determine which environmental and landscape variables influence the morphological characteristics of tadpoles from streams and ponds.\nWe found that the morphological traits of tadpoles are influenced mainly by physicochemical and microhabitat attributes, being distinct between ponds and streams. In ponds, water depth, pH, and the presence of vegetation influence the morphological traits of the tadpoles, while in the streams water pH, temperature, conductivity, total alkalinity, Alk HCO3, and microhabitat variables played a major role in defining the traits.\nOur results indicate that local components of habitat (water characteristics and microhabitat) influence functional traits of tadpoles in both ponds and streams, especially those supposedly related to locomotory, foraging and prey-detection abilities.\nCompeting Interest Statement\nThe authors have declared no competing interest.", "pred_label": "__label__POS", "pred_score_pos": 0.625163197517395} +{"content": "When people lack access to regular dental care, they often resort to visiting hospital emergency departments (EDs) for care — visits that are often costly and fail to address the underlying condition. This ineffective and inefficient system is not new, but the COVID-19 pandemic has highlighted and exacerbated it. At a time when ED capacity is strained, reducing preventable dental visits in these settings is of vital importance.\nThis visual report from CareQuest Institute for Oral Health, based on data from the Healthcare Cost and Utilization Project (HCUP), focuses on ED visits for non-traumatic dental conditions (NTDC) in Arizona.\nKey findings include:\nIn Arizona, adults ages 25 – 34 have the highest rate of ED use for NTDC, with about 95 visits per 10,000 people. Black residents in Arizona have the highest rate of ED use for NTDC, nearly three times higher than the rate for white residents and for Hispanic residents. Adults enrolled in Medicaid (61.4%) or who were uninsured (15.7%) made nearly 8 in 10 ED visits for NTDCs among patients ages 21 – 64.\nThe visual report also touches on promising solutions to expand access to care.\nYou may also be interested in: Financial Impact of Emergency Department Visits for Dental Conditions in Maryland: An Update, a report that underscores why expanding dental benefits to Medicaid participants is an opportunity to reduce ED visits for non-traumatic dental conditions. Recent Trends in Hospital Emergency Department Visits, an infographic that shows patients who visit hospital EDs for non-traumatic dental conditions can divert critical resources and create added stress for ED personnel. Emergency and Urgent Dental Visits Among Medicaid Enrollees from 2013 to 2017, a report to better understand the frequency of dental emergencies and the procedures performed during those emergency visits.", "pred_label": "__label__POS", "pred_score_pos": 0.8253474235534668} +{"content": "Business Services Courses\nThis course will cover the legislation associates with working in confined spaces. Identify what counts as a confined space, the potential hazards, safe operating procedures, emergency procedures and rescue. Persons requiring the knowledge to organise confined spaces working.\nEmployee absence can be costly in terms of both lost time and money. It impacts businesses, managers, and colleagues in ways that range from them having to take on extra work or undertake additional training, to experiencing additional stress and a drop in morale.\nIn any organisation, the traditional model of strict command and control wastes a significant amount of time and money. Mutual trust, employee motivation and readiness to perform can easily be undermined. Performance management, on the other hand, offers a different, much more effective approach.", "pred_label": "__label__POS", "pred_score_pos": 0.8724064230918884} +{"content": "This report first examines how standards systems are being applied to landscapes and jurisdictions. It then explores factors that are important to the effective application of sustainability strategies at a landscape level and identifies opportunities to strengthen the role that standards systems can play in implementing those strategies.\nThis webinar provided an opportunity for those working in the palm oil sector in Asia, including on the demand side, to hear about ongoing efforts in China, India, Indonesia, Malaysia and Singapore that are strengthening demand for sustainable palm oil such as youth engagement, industry platforms, and company rankings.\nThis ISEAL Community webinar introduces the draft Verification of Jurisdictional Claims guide and the good practices that should underpin claims made about progress in jurisdictional initiatives. It touches on why jurisdictional verification is relevant for sustainability standards and potential synergies.\nLandscape, jurisdictional and other regional approaches are gaining momentum as potential tools for scaling-up the sustainable sourcing of commodities. This briefing aims to assist sustainability standards in assessing these new approaches by providing background information and five ‘entry points’ for exploring potential engagement.\nThis blog outlines a set of key messages on due diligence and standards systems in the context of TFA letter to the European Commission.", "pred_label": "__label__POS", "pred_score_pos": 0.9965417981147766} +{"content": "Among the many lessons that the pandemic has taught us as a country and one of the common challenges that has arisen, is adapting to the relatively unfamiliar online working space. Over the last 18 months, it has become more evident that South Africa, specifically in the NGO arena, is playing catch-up with digital technology to support and enhance our work.\nWith the immense challenges that come with navigating online tools, significant effort also been required to adapt to implementing meaningful programmes while working remotely. Navigating professional spaces with colleagues you have never met in person and attempting to cultivate a culture of collaboration and co-creation, despite having never shared a common workspace, has compelled us to learn new ways to purposefully develop synergy amongst teams. More importantly, it has required us to explore more ways to intentionally foster understanding of one another.\nWhen you look at the Activate Change Drivers and Wessa teams from an outside perspective you see a team that appears to have effortlessly navigated around these hurdles. But what is not seen are the countless hours that have been invested into intentionally adopting a culture of appreciation for the richness in diversity that exists within the team. The team is represented by five different ethnicities, two genders, three provinces, two countries, three religions, a spectrum of generations and vastly different lived experiences. We are a microcosm of the immensely diverse society that we all function within.\nHonouring this richness in diversity, from the lens of a growth mindset, has encouraged us as a team to explore the complexities and brilliance that comes with working with this diverse and dynamic group of people.\nWhen considering the current world we live in, expanding ones knowledge of various cultural contexts and identities urges us to more meaningfully consider the lived experiences of others. This is my advice: If we are open to learning from others’ lived experiences and sharing our own, a sense of trust, comradery and understanding can be developed. With this understanding follows the ability to think critically about the realities of others; and in turn allows us to develop empathy in our view of each other.\nMy key takeout is this: When we are able to connect with the humanity within others, we are better equipped to connect with the humanity within ourselves. This in turn influences the ways in which we choose to live; how we treat one another; and the decisions we make as leaders and fellow human beings.\nSo why does this matter?\nRecent articles in the media reported that South Africans participate in more than 2 000 protests across the country each year. That equates to more than five demonstrations per day. This shows that people are extremely unhappy with the state of our country and how services are delivered. This high rate of dissatisfaction highlights the immense outcry to our leaders to address the needs of all people, within the contexts of their lived experiences.\nAs leaders, when we are appointed to the roles we occupy, we are called to serve and represent the common interests of a larger group of society. Often leaders hold these positions because a majority of people elected them under the belief that their leadership will contribute to providing for the needs of the people. But how do we truly understand the needs of people?\nWe do so by gaining a deeper understanding and appreciation for the lived experiences and cultural contexts of diverse communities. This includes engaging in conversations with people from all demographics and through participation in multi-ethnic and culturally diverse activities. Willingness to discover more about a wider scope of identities encourages our actions as leaders to be informed and fuelled by empathetic and compassionate understanding.\nBy viewing the world through the lens of others, thinking of the lived experiences of others and acting in the best interests of others, our leadership is in turn governed by the well-being of our larger society, as opposed to being led by our own self-interests.\nWritten by Nelvia Rawheath, National Youth Resilience Initiative (NYRI) Project Manager, ACTIVATE! Change Drivers", "pred_label": "__label__POS", "pred_score_pos": 0.5353280901908875} +{"content": "Authors\nNontraditional intrinsic luminescence (NTIL) which always accompanied with aggregation-induced emission (AIE) features has received considerable attention due to their importance in the understanding of basic luminescence principle and potential practical applications. However, the rational modulation of the NTIL of nonconventional luminophores remains difficult, on account of the limited understanding of emission mechanisms. Herein, the emission colour of nonconjugated poly(methyl vinyl ether-alt-maleic anhydride) (PMVEMA) could be readily regulated from blue to red by controlling the alkalinity during the hydrolysis process. The nontraditional photoluminescence with AIE property was from the new formed p-band state, resulting from the strong overlapping of p orbitals of the clustered O atoms though space interactions. Hydrated hydroxide complexes embedded in the entangled polymer chain make big difference on the clustering of O atoms which dominates the AIE property of nonconjugated PMVEMA. These new insights into the photoemission mechanism of NTIL should stimulate additional experimental and theoretical studies and could benefit the molecular-level design of nontraditional chromophores for optoelectronics and other applications.\nChemRixv-SI-2021.5.20", "pred_label": "__label__POS", "pred_score_pos": 0.9670863151550293} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis report examines evidence on outcomes and the effectiveness of summer experiences for youth on academic learning, social and emotional development, physical and mental health, and safety.\nThis issue brief explores how strategies for increased support for expanded learning programs can help reduce the disparities in educational outcomes between student populations. It provides examples from California's efforts to use local funding to enable more lower-income students have access to enrichment opportunities in out-of-school time.", "pred_label": "__label__POS", "pred_score_pos": 0.9029460549354553} +{"content": "This project explores Interpersonal Psychotherapy for adults with depression. IPT is diagnosis-targeted, time-limited, present-focused treatment that encourages the client to regain control of their mood and functioning. IPT regards depression as a medical illness and as a treatable condition, often combined with medication management. IPT has been clinically tested with success in a series of trials for mood and non-mood disorders. This project describes the purpose of APT, its roots in Attachment and Communication theories, and research behind IPT. This project uses scholarly data bases to discuss future research and recommendations.", "pred_label": "__label__POS", "pred_score_pos": 0.672875165939331} +{"content": "News Releases Hawaii Tourism Authority Releases Hawaii Hotel Performance Report for August 2021\nFor Immediate Release: September 20, 2021\nHTA Release (21-33) HONOLULU – Hawaii hotels statewide reported substantially higher revenue per available room (RevPAR), average daily rate (ADR), and occupancy in August 2021 compared to August 2020 when the State’s quarantine order for travelers due to the COVID-19 pandemic resulted in dramatic declines for the hotel industry. When compared to August 2019, statewide RevPAR and ADR were also higher in August 2021 but occupancy was lower.\nAccording to the Hawaii Hotel Performance Report published by the Hawaii Tourism Authority (HTA), statewide RevPAR in August 2021 was $261 (+639.3%), with ADR at $355 (+124.2%) and occupancy of 73.4 percent (+51.2 percentage points) (Figure 1) compared to August 2020. Compared with August 2019, RevPAR was 6.9 percent higher, driven by increased ADR (+22.5%) which offset lower occupancy (-10.7 percentage points) (Figure 5).\n“The peak summer season ended with August revenue and room rates remaining strong for Hawaii’s hotel industry statewide compared to August 2019,” said John De Fries, HTA president and CEO. “However, the rise in COVID-19 cases and subsequent hospitalizations caused by the Delta variant reminds us that we’re still in a fluid situation as we approach the seasonally slower fall period for travel.”\nThe report’s findings utilized data compiled by STR, Inc., which conducts the largest and most comprehensive survey of hotel properties in the Hawaiian Islands. For August, the survey included 142 properties representing 45,886 rooms, or 85.0 percent of all lodging properties and 85.6 percent of operating lodging properties with 20 rooms or more in the Hawaiian Islands, including those offering full service, limited service, and condominium hotels. Vacation rental and timeshare properties were not included in this survey.\nIn August 2021, passengers arriving from out-of-state could bypass the State’s mandatory 10-day self-quarantine if they were fully vaccinated in the United States or with a valid negative COVID-19 NAAT test result from a Trusted Testing Partner prior to their departure through the Safe Travels program. On August 23, 2021, Hawaii Governor David Ige urged travelers to curtail non-essential travel until the end of October 2021 due to the Delta variant resulting in the state’s health care system being overburdened.\nHawaii hotel room revenues statewide rose to $433.4 million (+1,270.6% vs. 2020, +6.1% vs. 2019) in August. Room demand was 1.2 million room nights (+511.4% vs. 2020, -13.4% vs. 2019) and room supply was 1.7 million room nights (+85.4% vs. 2020, -0.8% vs. 2019) (Figure 2). Many properties closed or reduced operations starting in April 2020 due to the COVID-19 pandemic. Due to these supply reductions, comparative data for certain markets and prices classes were not available for 2020; and comparisons to 2019 have been added.", "pred_label": "__label__POS", "pred_score_pos": 0.5047736167907715} +{"content": "At TAILS we are indebted to our fosters who provide our rescue animals with a loving home environment while they wait for adoption to their forever homes.\nThis provides endless benefits for animals, allowing them to settle into a routine, and receive individual attention, care, good food, and exercise.\nFostering also can allow individuals who are not ready to commit to adoption have the opportunity to share their lives with an animal on a short-term basis while giving back to the animal community through this act of kindness.\nIf you’d like to go ahead, please complete our foster questionnaire for us.\nThis will help us to understand more about the type of animal you are looking for as well as your daily living circumstances, which can allow us to match the most suitable animal with you and your family.\nPlease take some time to answer the questions in the relevant questionnaire as thoroughly and honestly as possible and we will arrange an interview with you if we have potential matches.", "pred_label": "__label__POS", "pred_score_pos": 0.8775352239608765} +{"content": "The British Online Archives team have recently updated the collection,\nSlave Trade Records from Liverpool, 1754-1792. This collection allows researchers and students to explore Britain’s part in one of the darkest episodes in modern human history, the transatlantic slave trade.\nLiverpool’s pivotal location in the industry is explored through captain’s logs, financial accounts, order papers and private correspondence of those trying to find fortune in the city. Despite the one-sided nature of the documents, British Online Archives have sought to foreground the oppression experienced by the enslaved through new insights, a new collection description, and new marketing material. However, this oppression is never more present than through the documents themselves, in which financial accounts and correspondence outline the abhorrent way in which enslaved Africans were conceptualised merely in terms of commercial cargo.\nAs well as a newly curated collection homepage, Professor Kenneth Morgan has provided a detailed description of the collection, covering Liverpool’s historical role in the transatlantic slave trade, as well as more specific contexts surrounding the individual ships that sailed to Africa and the New World of the Americas.", "pred_label": "__label__POS", "pred_score_pos": 0.5031763315200806} +{"content": "As previously mentioned in this site, if one is in a vehicle accident it is very important that one gets a thorough and accurate medical assessment of any injuries sustained. This is particularly so with regard to any potential herniated disc injuries, as those who get herniated disc injuries may not realize these injuries as the symptoms may not immediately manifest.\nRecently, there was a bicycle accident in Aurora, Illinois, which underscores the importance of getting a thorough medical check after being in any type of vehicle accident. While the injuries sustained during this accident did not appear to involve a herniated disc injury, the severity of the injuries – apparent only after a few hours – underscores the time-critical nature of getting a timely, thorough medical examination.\nThe bicycle accident in Aurora is discussed in the July 18, 2014 Aurora Beacon-News article titled “Bicyclist realizes depth of injuries hours after Aurora crash.” As seen in the article, the bicyclist initially thought he was okay after the accident, only to encounter problematical health symptoms a few hours after the accident, including difficulty breathing and vomiting blood.\nAn excerpt from the article:\nHe was taken to the emergency room at Presence Mercy Medical Center in Aurora, where it was determined he had bleeding on his brain as well as possible internal bleeding.\nDoctors transferred Owens to Good Samaritan Hospital in Downers Grove for surgery.\nAdditional details regarding the accident can be seen in the Aurora Beacon-News article mentioned above.", "pred_label": "__label__POS", "pred_score_pos": 0.8719698190689087} +{"content": "The challenge- Tropical forests are global hotspots of biodiversity, play key roles in the global carbon and water cycle and deliver crucial ecosystem services but are threatened by human-induced climate change, deforestation and biodiversity loss. I focus on forests that regrow after complete forest removal for agriculture (secondary forests), because they cover large areas, have great potential to recover biodiversity and carbon, and are the basis for ecosystem restoration. The key challenge is to understand and predict forest resilience: when, and under what conditions are regrowing forests able to recover and have the same quality and functioning as old-growth forests?\nAims- This study aims to understand and predict the resilience of tropical forests to human-driven disturbance by analyzing the effects of (1) continent and biogeography, (2) climate, (3) landscape, and (4) biodiversity on forest recovery rate. Approach- I will use a pantropical approach by synthesizing current data and doing controlled experiments on three continents (Neotropics, Africa, and Australia) in climatically contrasting forest types (dry and wet forest). I will (1) assess long-term multidimensional resilience by expanding a unique Neotropical network of 60 sites to the pantropics, (2) analyse the role of the landscape on forest recovery by doing a natural experiment along forest cover gradients, (3) understand how different kinds of diversity affect succession and ecosystem functioning through a biodiversity removal experiment. Impact- This study addresses key questions in ecology and advances our understanding how human-driven climate change, landscape degradation, and biodiversity loss affect forest resilience and succession. The insights can be applied to (1) reduce human impacts on tropical forests, (2) design resilient and multifunctional tropical landscapes, and (3) design effective forest restoration strategies.", "pred_label": "__label__POS", "pred_score_pos": 0.9378377199172974} +{"content": "STEM drives innovation for everyone, but such innovation would not be possible without a diversity in perspectives. This lack of diversity represents a loss of talent and discovery, and thus, hinders further societal development. From a logistical standpoint, studies also show that companies with diverse workforces outperform others financially, with companies in the top 25% for gender diversity being 15% more likely to have higher financial returns. However, gender minorities are discouraged from pursuing STEM due to underrepresentation or discrimination, factors that are outside of their control.", "pred_label": "__label__POS", "pred_score_pos": 0.9750488996505737} +{"content": "Mobility and the supply chain have grown increasingly intertwined as the world continues to recover from the pandemic. We've watched over the past 1.5 years as supply chains ebbed and flowed as lockdowns disrupted the flow of goods; workforce disruptions became nearly unavoidable; and consumer demand for certain items spiked more drastically than even the most precise forecasting could have predicted.\nThose factors, among others, forced businesses across the global supply chain to more deeply embrace technology to ensure resilience, collaboration and connectedness. From factories and big box retailers to everything in between, investments in supply chain technology increased and mobility was central.\nEmpowering employees through contextual mobility\nGartner emphasized in its report, Future of Supply Chain: 5 Trends to Act on Now, that CEOs see digitalization as key to shaping their business over the next decade. Nearly 79% said an internet-/platform-based system is the most critical business model to support post-pandemic recovery.\nClick here to hear more about technology in the supply chain:\nMobility is playing an increasingly critical role in future-proofing supply chain operations thanks to its connectivity, collaboration and productivity. From a workforce enablement perspective, it's perhaps\nthe most important driver of business continuity, as it enables a level of operational flexibility that is hard to rival.\nWorkers today want, and often demand, some level of autonomy while on the job. And, they're increasingly vocal about the systems they wish to utilize at work. Mobile technology is no exception. The ubiquity of smartphones has significantly influenced the way workers across the supply chain want to do their jobs, primarily in the way mobile devices are used personally affects how employees want to use them at work.\nIn line with that, a national workforce survey conducted by TRUCE Software found 56% of employees believe it's their right to use their personal mobile devices during work. That's the significant majority who think the ability to use their phone on the job isn't just a nice-to-have benefit, but a right that is inherently theirs.\nThe research also found employees believe mobility is a key enabler of productivity. At nearly 62%, a significant majority of those surveyed said they agree mobile phones or tablets play a key role in helping them be productive at work.\nSo, how can employers utilize mobile technology to meet workers where they are, allowing the flexibility employees want from their devices without sacrificing safety?\nGiving employees access to everything they need when they need it, and never when they don’t\nWhile the tools that enable the work have changed over the past decade, how companies manage those tools remains based on an outdated paradigm that doesn't embrace the flexible nature of mobility and the fluidity of workers. That’s where the concept of context comes in. Businesses using contextual mobility management can limit the functionality of an employee's mobile device based on that person's environment, considering things such as what they are doing and what’s happening around them. As an employee's environment changes throughout a shift, their device permissions do too, automatically and in real time.\nThis ability to dynamically manage user permissions based on each employee eliminates the guesswork for the employee surrounding what is or isn’t considered acceptable use and enforces the business’ mobile usage policies without relying on employees to police themselves. It eliminates the all-or-nothing approach to mobile device management that many companies still utilize because they don't know there's a more personalized and seamless way to adjust access dynamically; it doesn't require manually regulating user permissions on an ongoing basis. When deemed appropriate, employees can utilize a device’s full range of capabilities. When those capabilities need to be scaled back to focus, those settings automatically take effect based on the employee's context.\nWhile mobile technology is beneficial and necessary, it is essential to recognize that it may not deliver the intended benefits in all situations. After all, what’s acceptable to do in one case — responding to email in the break room — may not be permitted in a very different situation — doing the same while operating heavy machinery or driving a vehicle. Thinking about the world as a series of “zones,” areas defined based on the level of risk, allows for creating rules specific to those environments or situations, whether that’s behind a desk at the office, in a meeting room or lab, driving on the road, working at a job site or anywhere on- or off-premises.\nAdvanced workforce mobility comes to life when mobile device policies are dynamically enforced based on the context of each user. This is the new model for the modern workforce. If you spend more time focused on prohibiting devices than allowing them, you know it's time to re-think your approach.", "pred_label": "__label__POS", "pred_score_pos": 0.8188446760177612} +{"content": "Predicting the evolution of phenotypic traits requires an understanding of natural selection on them. Despite its indispensability in the fight against parasites, selection on host immune defense has remained understudied. Theory predicts immune traits to be under stabilizing selection due to associated trade-offs with other fitness-related traits. Empirical studies, however, report mainly positive directional selection. This discrepancy could be caused by low phenotypic variation in the examined individuals and/or variation in host resource level that...\n1 citation reported since publication in 2016.", "pred_label": "__label__POS", "pred_score_pos": 0.5570629835128784} +{"content": "Perspectives in mathematical modelling for microbial ecology\nM.J. Wade, J. Harmand, B. Benyahia, T. Bouchez, S. Chaillou, B. Cloez, J.-J. Godon, B. Moussa Boudjemaa, A. Rapaport, T. Sari, R. Arditi, C. Lobry\nSchool of Civil Engineering & Geosciences, Newcastle University, Newcastle-upon-Tyne, UK.\nAbstract\nAlthough mathematical modelling has reached a degree of maturity in the last decades, microbial ecology is still developing, albeit at a rapid pace thanks to new insights provided by modern molecular tools. However, whilst microbiologists have long enjoyed the perspectives that particular mathematical frameworks can provide, there remains a reluctance to fully embrace the potential of models, which appear too complex, esoteric or distant from the “real-world”. Nevertheless there is a strong case for pursuing the development of mathematical models to describe microbial behaviour and interactions, dynamically, spatially and across scales. Here we put forward perspectives on the current state of mathematical modelling in microbial ecology, looking back at the developments that have defined the synergies between the disciplines, and outline some of the existing challenges that motivate us to provide practical models in the hope that greater engagement with empiricists and practitioners in the microbiological domain may be achieved. We also indicate recent advances in modelling that have had impact in both the fundamental understanding of microbial ecology and its practical application in engineered biological systems. In this way, it is anticipated that interest can be garnered from across the microbiological spectrum resulting in a broader uptake of mathematical concepts in lecture theatres, laboratories and industrial systems.\nKeywords: Mathematical modelling; Microbial ecology; Chemostat; Density dependence; Thermodynamics.", "pred_label": "__label__POS", "pred_score_pos": 0.5377498865127563} +{"content": "Motivating Factors for Engaging in Health IT Enabled QI\nGuidance for Health Center Leadership and Partners\nHealth centers across the country have a high EHR adoption rate and most have been using an EHR for several years. However, we know that the proliferation of EHRs and their companion reports have not always lead to accurate and robust data that can be used for quality improvement. Many challenges have been identified, including provider workflow and training issues, challenges with scalability, and limitations to data that can be extracted from various EHR systems. In response, a need has been identified for tools and resources that can guide health centers and those working with health centers through some key skill areas in the pursuit of Health IT Enabled QI.", "pred_label": "__label__POS", "pred_score_pos": 0.9788912534713745} +{"content": "The Multidisciplinary Information Research Symposium (MIRS), organized by the Universuty of North Texas (UNT) College of Information and partners, is a one-day research symposium to showcase the research efforts of information scholars and practitioners. It will be inclusive of workshops, sessions for ongoing and completed papers, posters, and a competition for dissertation presentations.\nAbstract: Organizations across all sectors are increasingly undergoing deep transformation and restructuring towards data-driven operations. The central role of data highlights the need for reliable and clean data. Unreliable, erroneous, and incomplete data lead to critical bottlenecks in processing pipelines and, ultimately, service failures, which are disastrous for the competitive performance of the organization.", "pred_label": "__label__POS", "pred_score_pos": 0.9977802038192749} +{"content": "Platform Governance refers to the policy, technical, and design decisions impacting a global network of internet users. However, there is presently no single source bringing together the diverse perspectives on the terminology used in Platform Governance. Terms like 'misinformation', 'online harassment', and 'terrorist content' are difficult to define and regulate. Words like 'engagement' and 'amplification' serve as euphemisms for features that have had a significant impact on democracy and human rights.Read more\nAbout this blog\nIn addition to academic publications and events, the Wikimedia/Yale Law School Initiative on Intermediaries and Information pursues a diverse research agenda related to emerging issues in internet governance, the right to information, digital rights, privacy and data protection, and content regulation online.\nThis space is a home for commentary and shorter-form discussions related to these issues, as well as a central repository of written works produced as part of the WIII program.\nThe views expressed on this blog belong to the author(s) and do not represent the views of Yale Law School or the Information Society Project.", "pred_label": "__label__POS", "pred_score_pos": 0.9220318794250488} +{"content": "This webinar provides an economic outlook of labour and materials, will provide Health and Safety Index benchmark results, factors impacting on poor contractor and supplier performance.\nOften organisations take a one-size-fits-all approach to managing risks when procuring goods and services. This often leads to complexities, clutter, non-compliance, and ineffective cultures. Requirements vary based on supplier maturity, procurement categories, economic trends and activities performed.\nWe will explore current procurement trends impacting goods and services, including commercial risks, health and safety practices and behaviours.\nKey takeaways:\nMark Wright is a trusted risk, health and safety professional committed to preventing harm and enabling high levels of performance. Mark is the Managing Director of FEFO Consulting and the Health & Safety Index. His career has included work as Non-Executive Director, several senior leadership positions and work over 15 countries across mining, oil & gas, facilities management, construction and utilities.\nMark has proven track record in leading transformation projects, leadership development, strategy deployment and enabling high-performance cultures. He also has strong expertise in Critical Risk Management (CRM), Safety in Design (SiD), contractor management incident investigations and assurance activities.\nMark previously worked with SafeWork NSW as a Prosecutor and with multi-national companies such as Lend Lease, Transfield Services and Rio Tinto. He has also led many consulting projects with organisations such as Glencore JLL, Boral, Westpac, Australian Institute of Company Directors, WorkSafe NZ, Nine Network and several government agencies. FEFO Consulting’s success was recently recognised as a finalist with the Australian Small Business Champion Awards.\nMark has a range of qualifications including Bachelor of Science, Post Graduate Diploma in Safety, lead auditor, ICAM / Comcare investigator and is a Graduate of the Australian Institute of Company Directors (GAICD).\nColin Williams is the Founder and Director of heyProcurement where he helps companies sell to buy better. He is a Procurement, Supply Chain and Business Consultant expert, specialising in high-value procurement strategies for large-scale operations as well as medium-sized entities in Australia and Asia.\nThis includes experience in strategy development, value and revenue enhancement, cost optimisation and process improvement. He has led global contracts of more than $8 billion and worked with will global companies such as Rio Tinto.", "pred_label": "__label__POS", "pred_score_pos": 0.5202623605728149} +{"content": "Image credit: @zgc1993\nThis week’s challenge activity was to transform a piece of media into a new artefact, using one of the techniques discussed in the week’s readings.\nAs much as it pains me to admit, I failed this challenge.\nThe existing media that I chose to modify was Eric Clapton’s 1992 acoustic rendition of Layla. A song near to my heart, in that my daughter – Layla-Mae Gracie – is a namesake to it.\nI was quick to choose this song as my existing artefact. I regularly use it as a lullaby, and I planned to create something of sentimental value. I was going to modify the song into a tattoo design or printed design to hang in Layla’s nursery.\nI made that decision before picking a transformation technique. This is where the challenge attempt derailed. I had created two main roadblocks for myself:\nThe first, I made it difficult to impartially follow any transformation technique. I tried to use SCAMPER, but I found myself forcing the steps around my planned end product. I should have explored the remediation process freely, and reached a new media organically.\nThe second, I added an element risk to the activity. Creating a design that I was pleased with was suddenly important. If my end product wasn’t of a high enough standard, I wouldn’t be able to use it as I hoped.\nIn a sense, I had made the challenge failable through the constraint I had set for myself. As a direct result, I found the challenge to be quite frustrating. After commiting several hours of work with little progress, I decided to abandon the challenge.\nWithout the sentimental aspect, I could have focused on conjuring creativity. And I would have been satisfied with the end product at any level of quality.\nI imagine I would have avoided a heap of frustration as well.\nWith all this being said, I still took a lot of value from the activity. I was suprised at how following my initial idea had impeded my ability to throw myself into the challenge. By practising the SCAMPER technique with restrictions, I now appreciate how it could be applied as a creativity exercise\n(Dam & Siang, 2020). I found the method to be fitting as a warm-up for channelling creativity, rather than a means of concept formulation, ideation or problem solving.\nFinally, the most valuable takeaway was the experience of failing an exercise on this journey. I’ll surely encounter other exercises of the next two years that don’t go to plan. What matters is that there’s really been no penalty for failing, and the failure was as valuable as (if not even more valuable than) the success would have been.\nI’ll remember this moving forward, and throw myself into the deep end as often as possible.\nMonday 9th November.\nIt’s been a short while since I posted the above, and I’d like to revisit something I wrote:\n“…I would have avoided a heap of frustration as well.”\nThe frustration I felt stemmed from the inability to deliver an artefact that I had assigned personal, sentimental value to. But that begs the question,\nif that value was self-assigned, where was my frustration directed?\nWas that frustration at myself for setting an unreasonable objective, on top of the weekly challenge objective? Perhaps the frustration was at the constraints of the weekly challenge, for not affording me the opportunity to create something of deeper value?\nIt may have been frustration at the SCAMPER method for being an ineffective tool for creating what I had set out to create. If that was the case, then the frustration may have been misdirected; to say that I was annoyed at SCAMPER would be to use it as a scapegoat. It\nwas me that opted to use the method.\nThrowing introspection aside, some extraneous factor might have just put me in a bad mood that day.\nIt’s difficult to say now that so much time has passed. Next time I encounter a frustating situation, I’ll need to take a step back for some affective reflection.\nThese considerations might suggest that I think frustration is inherently negative. I actually think that frustration in the context of work is a natural response to an ineffective approach or process.\nHarvey Deutschendorf, 2018, of Fast Company agrees that, “it’s not the situations themselves that make or break us, it’s how we respond to them.”\nWhat draws the line between positive and negative is my response. I could let it impede my ability to work. Worse, create an unhappy environment for myself and my colleagues. Or I could identify the source of frustration, resolve it, and work better than ever.\nBest practice in the face of frustration is to be remediative, not reactive.\nReferences\nDAM, R. S. and Siang, T. Y. 2020. ‘Learn How to Use the Best Ideation Methods: SCAMPER’.\nInteraction Design Foundation. Available at: https://www.interaction-design.org/literature/article/learn-how-to-use-the-best-ideation-methods-scamper [accessed 22/12/2020].\nDEUTSCHENDORF, H. 2018. ‘5 Emotionally Intelligent Habits For Handling Work Frustrations’.\nFast Company. Available at: https://www.fastcompany.com/40561640/5-emotionally-intelligent-habits-for-managing-work-frustrations [accessed 22/12/2020].\nWALTER, E. 2013. ’30 Powerful Quotes on Failure’.\nForbes. Available at: https://www.forbes.com/sites/ekaterinawalter/2013/12/30/30-powerful-quotes-on-failure/ [accessed 22/12/2020].", "pred_label": "__label__POS", "pred_score_pos": 0.6216574311256409} +{"content": "Recovering from COVID-19: economic scenarios for South Africa\nAs the South African economy emerges from the downturn induced by COVID-19, policy makers are concerned with recovery, reconstruction, and transformation. This paper focuses on the recovery from the severely depressed levels of economic activity that occurred in April 2020. However, before considering the period after the economic trough of April 2020, a mention of economic conditions prior to the pandemic is worthwhile. In brief, economic performance was terrible by almost any metric. Furthermore, economic performance had been poor since 2008, with evidence pointing to ongoing deterioration culminating in the fourth quarter of 2019, when per capita GDP contracted, unemployment ticked upwards to its highest level since 1994, productivity declined, and inequality worsened.", "pred_label": "__label__POS", "pred_score_pos": 0.8050187230110168} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis report summarizes research on changes in licensing requirements and policies for child care centers, family child care homes, and group care homes. It compares 2017 data to that of 2014.\nThis practice brief explores some of the current mental health needs of school-age children, their families, and the OST workforce. In addition, this brief discusses the social and emotional constructs that promote resilience, as well as examples of mental health supports that states and local jurisdictions can consider for collaborative implementation.\nThis issue brief shares data from the Census Bureau Household Pulse Survey that indicate that 19% of Hispanic households and 22% of Black households were food insufficient this summer compared to 14% of all households and 9% of white households. Food insufficiency puts children at higher risk of health, academic, behavioral, and emotional problems.\nThis policy brief summarizes findings from 22 focus groups with family child care (FCC) providers in CA, FL, MA, and WI during spring 2020. It reviews challenges that FCC providers faced as they provided care during the pandemic and the strengths they have that make them uniquely suited to respond to child care needs.\nThis review of state plans for school reopening provides examples for ways states and districts can coordinate with afterschool programs to support their capacity, leverage resources, and support students and families.\nThis issue brief explores evidence-based strategies to prevent adverse childhood experiences (ACEs).\nThere are four issue briefs as part of Reviewing State Policies series: (1) Supporting Financial Stability for Providers; (2) Child Care Ratios and Class Sizes; (3) Protecting Health and Safety; and (4) Support for Families. Each brief provides an overview about state policies emerging during this time of COVID-19, with multiple state policy examples that other states can learn from.\nThis issue brief provides a blueprint for how after school programs can help during COVID-19 by building school and community partnerships. It provides a useful chart to guide the response whether schools are providing in-person learning, remote learning, or a hybrid approach.\nThis issue brief explores how COVID-related school closures are likely to effect children’s academic progress, access to resources, and overall health and wellbeing and how systemic inequities exacerbate the impact for some groups.\nThis issue brief provides recommendations for how to best support home-based child care providers during COVID-19, recognizing that this is an especially important part of the supply right now, and was already seeing instability and a decline in providers.", "pred_label": "__label__POS", "pred_score_pos": 0.7329493165016174} +{"content": "The Brussels-based executive recalled that the European Medicines Agency had not yet validated the principle of a third dose, although eight countries have decided to do so. The Commission will not take responsibility for any problems.\nDo we really need Covid-19 Vaccine Booster?\nEuropean Union (EU) member countries that have decided to launch Covid-19 vaccine booster campaigns may be exposing themselves to increased legal risks, as the administration of a booster has not yet been recommended by the European Medicines Agency (EMA), the European Commission reminded on Thursday, August 26, 2021.\nThe EMEA, the European medicines regulator, has repeatedly stated that it does not have sufficient data to make a judgement on the possible need for a Covid-19 vaccine booster and its timing.\nBooster doses are not currently included in marketing authorizations for Covid-19 vaccines and have not yet been scientifically assessed by the EMEA due to insufficient data, the European Commission noted in a statement to Reuters on Thursday. The responsibility for including the recalls in national vaccination campaigns therefore lies with member states, the Commission said in its message.\nEight European countries to launch Vaccine Booster\nThis could mean that in the event of unexpected adverse events that could be specifically attributed to the recalls, the states involved could bear the brunt of any lawsuits or compensation claims. However, laboratories would not be entirely exempt from liability, for example in the case of a post-recall adverse event related to a production problem.\nAlthough the booster dose is not currently included in European marketing authorizations, eight European countries – including France – have already decided to recommend a Covid-19 booster dose, and nearly 15 others are reportedly in the process of doing so.\nThe French Prime Minister, Jean Castex, announced on Thursday morning on RTL that the Covid-19 vaccine booster campaign would be launched in September.\nThe French National Authority for Health (HAS), which recommended on Tuesday to target the 65 years old and more for this vaccination campaign, specified that its opinion was conditioned to the validation of this recall by the European Agency for Medicines.\nAccording to the European Centre for Disease Control and Prevention (ECDC), in addition to France, Austria, Belgium, Hungary, Liechtenstein, Lithuania, Luxembourg and Slovenia already recommend these recalls. Germany plans to do the same in the fall, and 13 other countries, including Italy, are considering it.\nOutside the EU, the United States plans to expand its booster campaign starting September 20, and Israel – which has an agreement with Pfizer to provide data – has been gradually expanding its campaign since late July.\nWhat about the unexpected Adverse Events?\nCountries that have implemented booster campaigns cite the decline in immune response over time in vaccinated individuals, as well as the need to stem recent outbreaks associated with the highly contagious Delta variant of the SARS-CoV-2 coronavirus, first discovered in India.\nThe World Health Organization (WHO) has repeatedly advised against such booster campaigns in recent months, citing improved vaccine coverage in developing countries as a priority.\nEuropean liability and compensation rules apply in case of unexpected adverse events related to the general characteristics of the product or its manufacture. Each supplier of Covid-19 vaccines has negotiated with the European authorities specific clauses in this regard, which remain largely confidential.\nPotential compensation for adverse events related to COVID-19 vaccines is managed at the national level. In France, they are managed by the National Office for Compensation of Medical Accidents, Iatrogenic Affections and Nosocomial Infections (Oniam).", "pred_label": "__label__POS", "pred_score_pos": 0.818297266960144} +{"content": "ABSTRACT\nTranslation of mRNA into a polypeptide is terminated when the release factor eRF1 recognizes a UAA, UAG, or UGA stop codon in the ribosomal A site and stimulates nascent peptide release. However, stop codon readthrough can occur when a near-cognate tRNA outcompetes eRF1 in decoding the stop codon, resulting in the continuation of the elongation phase of protein synthesis. At the end of a conventional mRNA coding region, readthrough allows translation into the mRNA 3’-UTR. Previous studies with reporter systems have shown that the efficiency of termination or readthrough is modulated by\ncis-acting elements other than stop codon identity, including two nucleotides 5’ of the stop codon, six nucleotides 3’ of the stop codon in the ribosomal mRNA channel, and stem-loop structures in the mRNA 3’-UTR. It is unknown whether these elements are important at a genome-wide level and whether other mRNA features proximal to the stop codon significantly affect termination and readthrough efficiencies in vivo. Accordingly, we carried out ribosome profiling analyses of yeast cells expressing wild-type or temperature-sensitive eRF1 and developed bioinformatics strategies to calculate readthrough efficiency, and to identify mRNA and peptide features which influence that efficiency. We found that the stop codon (nt +1 to +3), the nucleotide after it (nt +4), the codon in the P site (nt -3 to -1), and 3’-UTR length are the most influential features in the control of readthrough efficiency, while nts +5 to +9 and mRNA secondary structure in the 3’-UTR had milder effects. Additionally, we found low readthrough genes to have shorter 3’-UTRs compared to high readthrough genes in cells with thermally inactivated eRF1, while this trend was reversed in wild-type cells. Together, our results demonstrated the general roles of known regulatory elements in genome-wide regulation and identified several new mRNA or peptide features affecting the efficiency of translation termination and readthrough. AUTHOR SUMMARY Of the 64 codons that exist for translation of the genetic code into a polypeptide chain, only UAA, UAG, and UGA signify termination of continued protein synthesis. However, the efficiency of termination is not the same for different mRNAs and is likely influenced by mRNA sequences proximal to these “stop” codons. Here, we sought to expand current understanding of termination efficiency to a genome-wide scale. Our analysis identifies novel mRNA features that may regulate the efficiency of translation termination, including the identities of the stop codon, the penultimate codon, the proximal nucleotides, and the length of mRNA 3’-untranslated region. As ∼11% of human diseases are caused by mutations that introduce premature stop codons, resulting in both accelerated mRNA decay and truncated protein product, our findings are valuable for understanding and developing therapeutics targeting the termination step of mRNA translation. Competing Interest Statement\nA.J. is co-founder, director, and SAB chair of PTC Therapeutics Inc. All other authors declare no competing interests.", "pred_label": "__label__POS", "pred_score_pos": 0.5080033540725708} +{"content": "Following the introduction of the system, we worked with the customer to determine a quality level. This enabled us to set a clear standard for inspections – something that had not been done previously – and target stable quality.\nVisualizing inspection results\nDuring visual inspections, standards tended to differ between each inspector and supervisor. However, displaying inspection standards and the results they produce on screen eliminated the need for excessive quality levels.\nPreventing missed detection of major defects\nWhile significant defects were overlooked in the past, this issue was eliminated by introducing the system.\nReducing operator load and personnel shortages\nAutomating the inspection of components with high quality requirements, especially the critical areas of those components, helped to reduce the mental strain placed on personnel.\nAutomating inspection also helped to reduce the physical strain experienced by personnel when inspecting heavy components.\nWhile retention rates for visual inspectors had been poor, process automation successfully cut both recruitment and training costs.\nIncreasing cost savings\nAlong with inspection, automating the entire process from loading to unloading made it possible to halve the number of personnel required.\nIntroducing the system effectively reduced defect rates and disposal costs as well as the work hours required for repairs.", "pred_label": "__label__POS", "pred_score_pos": 0.9378398060798645} +{"content": "Carpal tunnel syndrome is characterized by pain, numbness, and tingling that occurs in one or both hands. It often wakes people from their sleep, leaving them feeling like they have to \"shake their hands out\" to make the pain and symptoms go away...\nOsteopathy is highly successful in treating carpal tunnel syndrome (CTS), especially using what they call the ‘opponens roll’ manoeuvre. In a small study to assess the effectiveness of this procedure", "pred_label": "__label__POS", "pred_score_pos": 0.9967886209487915} +{"content": "However, in severe cases, RSV infection can spread to the lower respiratory tract, causing pneumonia or bronchiolitis, warns the Mayo Clinic.\nSevere signs and symptoms may include:\nFever Severe cough Wheezing — a high-pitched noise that’s usually heard on breathing out (exhaling) Rapid breathing or difficulty breathing — the person may prefer to sit up rather than lie down Bluish colour of the skin due to lack of oxygen (cyanosis).\nAs the Mayo Clinic points out, because RSV and COVID-19) are both types of respiratory viruses, some symptoms of RSV and COVID-19 can be similar.\n“In children, COVID-19 often results in mild symptoms such as fever, runny nose and cough,” explains the health body.", "pred_label": "__label__POS", "pred_score_pos": 0.6718066930770874} +{"content": "Energy Efficiency and Fluctuations in CO2 Emissions Staff Working Paper 2021-47 Soojin Jo, Lilia Karnizova Carbon dioxide emissions have been commonly modelled as rising and falling with total output. Yet many factors, such as energy-efficiency improvements and shifts to cleaner energy, can break this relationship. We evaluate these factors using US data and find that changes in energy efficiency of consumption goods explain a significant proportion of emissions fluctuations. This finding also implies that models that omit energy efficiency likely overestimate the trade-off between environmental protection and economic performance. Content Type(s): Staff research, Staff working papers Topic(s): Business fluctuations and cycles, Climate change, Econometric and statistical methods JEL Code(s): E, E3, E32, Q, Q4, Q43, Q5, Q50, Q55", "pred_label": "__label__POS", "pred_score_pos": 0.7080701589584351} +{"content": "Killer robots and their use will be debated during a meeting of experts at the United Nations in Geneva, amid fears that once created they could pose a “threat to humanity”.\nProf Ronald Arkin and Prof Noel Sharkey will debate the need for so-called killer robots during the UN Convention on Certain Conventional Weapons (CCW), marking the first time the issue of killer robots has been discussed within the CCW.\nKiller robots are autonomous machines able to identify and kill targets without human input.\nFully autonomous weapons have not yet been developed but technological advances are bringing them closer to existing.\nProf Sharkey, a member and co-founder of the Campaign Against Killer Robots and chairman of the International Committee for Robot Arms Control spoke ahead of the conference and warned autonomous weapons systems cannot be guaranteed to \"predictably comply with international law.\"\nHe told the BBC: \"Nations aren't talking to each other about this, which poses a big risk to humanity.\"\nBut Prof Arkin claimed killer robots could help reduce non-combatant casualties and may be more effective at determining when not to engage with a target than humans are.\nHowever, he expressed concerns that the robots could be rushed into battle prematurely. \"I support a moratorium until that end is achieved, but I do not support a ban at this time,\" Prof Arkin explained.\nA full report on the discussions will be presented to the CCW in November\nIn March, the UN Human Rights Council heard concerns surrounding the ethical dangers such machines could pose.\nChristof Heyns - the UN special rapporteur on extrajudicial, summary or arbitrary executions for the Office of the High Commissioner for Human Rights – called for a moratorium on such technology to prevent their deployment on the battlefield.\nIn a report submitted ahead of his address, he said: “robots should not have the power of life and death over human beings.”\nMr Heyns highlighted the US’s counter-terrorism operations using remotely-piloted drones to target individuals and argued: “there is reason to believe that states will, inter alia, seek to use lethal autonomous robotics for targeted killing.”\nExamples of autonomous weapons systems already in use include the US Navy’s Phalanx gun system that automatically engages incoming threats and the Israeli Harpy drone that automatically attacks radar emitters.\nJoin our new commenting forum\nJoin thought-provoking conversations, follow other Independent readers and see their replies", "pred_label": "__label__POS", "pred_score_pos": 0.8309566378593445} +{"content": "The premise that Active Queue Management (AQM) is effective in both quantitative and qualitative settings in residential and enterprise networks has repeatedly been established in multiple papers from academic journals along with private studies in addressing bufferbloat, characterized as excessive latency because of heavy network utilization. However, the presence and understanding of bufferbloat mitigation is absent and not well-known in the Philippine Internet of Things space except enthusiasts, willing to take the time to examine the concept along with its benefits. Hence, this paper examines possible reasons as to why AQM is not widely adopted by Philippine consumers and industries in increasing productivity considering the COVID-19 Pandemic: a lack of basic understanding of bufferbloat and its implications, the complexity of the concept, the know-how required to execute its implementation being far too high, and the lack of perceived benefit by existing telecommunications players in the country.", "pred_label": "__label__POS", "pred_score_pos": 0.9694142937660217} +{"content": "The early months and years of a child’s life are often the most challenging and exciting moments for parents. For those experiencing an autism diagnosis, their lives change overnight. Expectations, hopes, and dreams for their child shift as new expectations and challenges arise. Early intervention programs can make a huge difference in a child’s autism…\nAn autism diagnosis can be one of the most significant challenges a child and their parents undergo. Overnight a family’s life can change. Not only do hopes, dreams, and expectations for your child’s future shift, so does your own parenting. No matter the severity of an autism diagnosis, parents should never go through the journey…\nOne of the first challenges parents face when their child is diagnosed with ASD is finding the proper support and resources for their family. There is a wealth of autism resources, support groups, and therapy programs around the world. However, it can be a challenge finding autism support close to home. Educating yourself and your…\nAutism spectrum disorder (ASD) covers a wide range of symptoms and developmental challenges for young learners. While some struggle with verbal communication, others may have more difficulty reading emotions. Because there are many types of autism, therapy can range from multimodal to a single type of therapy, such as applied behavioral analysis. However, we take…\nParents of children with autism often wonder what they can do to help their children thrive during autism treatment. A diagnosis for autism spectrum disorder may frighten and relieve you. At least you have a name for what’s happening to your child and makes them different. However, conflicting treatment advice might confuse you. EMIT Therapeutics provides treatment…\nA pandemic can seem to make the world stop, including the education and support your child with autism needs. COVID-19 autism treatment is different but remains essential. If your child’s access to autism treatment and autism therapies has changed or become nonexistent, it’s time to look for new solutions. At EMIT Therapeutics, we offer ways…\nFor many children with autism, communication, learning, and functioning in daily life is a challenge. Yet, for many, autism treatment can be helpful. Applied behavior analysis or ABA is one tool that may help give your son or daughter the support they need to learn and grow. At EMIT Therapeutics in New Jersey, we offer…\nMany times, the most frightening of situations for parents with children who have autism is self-injury. You may be able to protect your child from many things, but shielding them from this type of behavior is difficult. Understanding self-injurious behavior is not simple, either. For those who have children with autism engaging in this behavior,…\nThe sooner you get help for autism, the better. An early intervention program can make a big difference in the quality of a person’s life. Early diagnosis and treatment may have significant benefits to your child while also improving the relationship you have with him or her. At EMIT Therapeutics, we offer comprehensive autism treatment…\nIf you have a child with autism, there are many hurdles to overcome in your journey as a parent. However, with the proper guidance and resources, you can be successful in helping your child in life. If your child was recently diagnosed with autism, you might have various questions related to autism. One pressing issue…", "pred_label": "__label__POS", "pred_score_pos": 0.6453481912612915} +{"content": "The issuance of catastrophe bonds in Hong Kong can help diversify Mainland insurers' losses from natural disasters and enhance the risk-sharing mechanism.September 29, 2021\nA Kroll survey found that 82% of senior decision-makers for risk strategy felt corruption significantly impacted their organisations in 2020.September 21, 2021\nHe Xingxiang is the second most senior official at China Development Bank to become the subject of a corruption probe.September 14, 2021\nSEBI has clarified that asset managers should disclose scheme \"risk-o-meters\" in all disclosures including promotional material from 1 October.September 7, 2021\nA higher leverage ratio will help banks reduce import costs, increase quality capital, and enhance their ability of banks to absorb riskes, Bangladesh Bank said.August 22, 2021\nThe goal is to push criminals to the margins and into the hands of non-compliant operators, where law enforcement can be deployed more effectively.August 3, 2021\nThe report indicates that the risks were known, but responsible parties in the first and second lines simply failed to act.July 30, 2021\nMAS invites fintechs, solution providers and FIs to submit innovative solutions to help validate the fairness of AI solutions for selected banking use cases.July 13, 2021\nMajor shareholders cannot use borrowed funds to invest in banks, take out loans from the banks they invest in, or have cross-shareholdings with other banks.June 22, 2021\nRegulators inspected Baoshang Bank on 50 occasions and deliberately avoided parts of the business that had significant potential risks.May 28, 2021", "pred_label": "__label__POS", "pred_score_pos": 0.6468344926834106} +{"content": "Dietitians can help and advise patients who may need extra nutritional support before, during and after treatment for a sarcoma. Dietitians are HCPC (Health Care Professionals Council) registered and aim to support with translating complex nutrition information into practical advice to treat medical conditions and facilitate lifestyle choices.\nThey take a holistic approach to nutritional care for all patients, including those with complex needs.\nThe dietitians often carry out pre-operative nutritional assessments, reports and treatment plans for adult and paediatric patients who are identified as having pre-existing nutritional concerns.\nPatients undergoing treatment for a head and neck sarcoma, or sarcoma of the abdomen may see a specialist dietitian as part of their treatment.\nInformation on Healthy Eating", "pred_label": "__label__POS", "pred_score_pos": 0.6903629302978516} +{"content": "On January 14, 2021, President-elect Joe Biden released his $1.9 trillion emergency stimulus plan, designed primarily to guide the country through the next medical and economic stages of the COVID-19 pandemic. The American Rescue Plan (“ARP”) also includes non-COVID-19 related proposals, such as a mandatory $15 per hour minimum wage and funding to improve cybersecurity.\nAs COVID-19 cases continue to rise across the nation, the District of Columbia, Maryland, and Virginia all recently have implemented additional mitigation measures that impact business operations. Below is a summary of the key restrictions of which businesses within the DMV should be aware.\nDistrict of Columbia\nThe District of Columbia maintains a compilation of…\nThe U.S. Department of Labor’s Occupational Safety and Health Administration (“OSHA”) recently updated its COVID-19 Frequently Asked Questions (“FAQ”) regarding employers’ reporting obligations during the COVID-19 pandemic.\nAs previously reported, effective as of May 26, 2020, OSHA has declared COVID-19 a recordable illness for\nall employers. Thus, employers are responsible for recording workplace cases…\nAs featured in #WorkforceWednesday: The latest FAQs from OSHA recommend wearing face masks, among other suggestions, for employees returning to work. Attorney Robert J. O’Hara discusses the significance of OSHA’s decision to issue recommendations, rather than guidance, and how rules on face masks in the office may differ at the state and local levels.\nOn May 19, 2020, the U.S. Department of Labor issued two COVID-19 related Enforcement Memos to provide updated guidance to OSHA investigators: (1) Revised Enforcement Guidance for Recording Cases of Coronavirus Disease 2019 (COVID-19) (“Revised Recordkeeping Guidance”), which reinstates employers’ recordkeeping obligations for COVID-19 cases (29 CFR Part 1904) and (2) Updated Interim…\nOn April 13, 2020, the Occupational Health and Safety Administration (“OSHA”) of the U.S. Department of Labor (“DOL”) issued an industry-specific alert for the package delivery industry during the COVID-19 pandemic.\nThe alert provides guidance tailored to the package delivery industry, but it is equally useful for any company using its own employees to deliver…\nOn April 13, 2020, the Occupational Safety and Health Administration (‘OSHA”) of the U.S. Department of Labor issued a guidance memorandum (“Memorandum”) to its Area Offices and compliance safety and health officers for handling COVID-19 referrals, complaints, and severe illness reports.\nThe Memorandum articulates the procedures OSHA will use to prioritize enforcement responses, and details…\nAs we previously reported in our “\nSummary of OSHA Guidance on Preparing Workplaces for COVID-19,” the U.S. Department of Labor (“DOL”) has provided detailed directions for employers with respect to ensuring an OSHA-compliant workplace during the COVID-19 pandemic. On April 10, 2020, the DOL issued a memorandum providing interim guidance on enforcement of… USCIS Completes the Initial Selection Process\nOn April 1, 2020, U.S. Citizenship and Immigration Services (‘USCIS”) announced that the initial selection of H-1B cap-subject registrations for fiscal year (“FY”) 2021 was completed. Petitioners who electronically registered beneficiaries in the H-1B registration process and were selected through the random selection process may file their H-1B cap…\nAs featured in #WorkforceWednesday: Last week, Congress passed and President Trump signed the CARES Act, a $2+ trillion stimulus law, which is the largest stimulus in U.S. history. Attorney Paul DeCamp discusses how this law could benefit certain employers during this unprecedented time in the following video interview.", "pred_label": "__label__POS", "pred_score_pos": 0.8409043550491333} +{"content": "In early 2009, ActionAid and Women for Women International Nigeria embarked on a two-year, multi-country initiative entitled “Access to Justice for Women”. Funded by the UK’s Department for International Development/UK aid and the Danish Ministry of Foreign Affairs, the project focused on ensuring and increasing women’s access to justice in conflict and post-conflict environments and was implemented in seven African states: Burundi, the Democratic Republic of Congo (DRC), Liberia, Nigeria, Sierra Leone, Somaliland and Uganda.\nThis publication is intended as a reference tool for other organisations working on issues of access to justice for women, specifically those that are designing and implementing access to justice for women projects. It outlines some of the key strategies and tactics employed in the seven project countries to increase women’s access to justice, and analyses their respective successes and shortcomings.", "pred_label": "__label__POS", "pred_score_pos": 0.8637710809707642} +{"content": "Imagining Sex:Pornography and Bodies in Seventeenth-Century England: Pornography and Bodies in Seventeenth-Century England\nOUP Oxford, 6 sep. 2007 - 334 pagina's\nImagining Sex is a study of pornographic writing in seventeenth-century England. It explores a wide variety of written material from the period to argue that, unlike today, pornography was not a discrete genre, nor was it one that was usually subject at this time to suppression. Pornographic writing was a widespread feature of a range of texts, including both popular literature (ballads, news-sheets, court reports, small books, and pamphlets) as well as poetry, drama andmore specialised medical books. The book analyses representations of sex, sexuality and eroticism in historical context to explore contemporary thinking about these issues, but also about broader cultural concerns and shifts in attitudes. It questions both modern feminist and psychoanalytical interpretations ofpornography, arguing that these approaches are neither appropriate nor helpful to an understanding of seventeenth-century material.Through discussions of sex and reproduction, homosexuality, flagellation, voyeurism, and humour, the book explores the nature of early modern sexual desire and arousal and explores their relationship to contemporary understandings about how the body worked. Imagining Sex presents a radically new interpretation of pornography in this period, arguing that concerns about fertility were at the heart of representations of bodies and sex, so that images of pleasure were entwined with ideasabout conception and reproduction. It also shows that these texts legitimized the (sexual) pleasure of the reader by highlighting the pleasure of looking and the incitement to sexual action that it provided.\nWat mensen zeggen - Een review schrijven\nWe hebben geen reviews gevonden op de gebruikelijke plaatsen.\nOverige edities - Alles weergeven\nImagining Sex: Pornography and Bodies in Seventeenth-Century England\nSarah Toulalan\nGedeeltelijke weergave - 2007", "pred_label": "__label__POS", "pred_score_pos": 0.5923534035682678} +{"content": "June 21, 2007 Drop in commission by property agent should not mean drop in service AS THE property market is booming, more people will join the ranks of property agents to make a quick buck. However, I wonder if the level of professional service will be the same, even if buyers and sellers are willing to pay a commission for their service. I have recently completed my resale application for a unit in Sengkang. The agent who serviced me left me wondering how many agents are like him. According to the Institute of Estate Agents (IEA), the buyer has to pay 1 per cent to the agent for his service. However, my agent was willing to lower his commission to help his brother sell the flat quickly. He also asked us to give up our agent who recommended us to the flat because he had an argument with her. Before signing the option to purchase (OTP), he made several promises to us, including allowing us to bring the contractor after the OTP was sign and driving us to HDB Hub for our two appointments as we have three children and no car. His sincerity persuaded us to sign on the dotted line. However, then things started to change. The things he promised were not delivered. After the second appointment, he did not even tell us the owner had kept the letterbox keys. Even worse, the house was full of defects that were not easily spotted during the final inspection. One may wonder: Since I am paying less commission, am I asking too much? Let me put it this way. If you go to a fast-food restaurant and only buy a drink that costs $2, do you expect less service than someone who buys a $10 meal? Corresponding with the agent's agency was futile as they were only interested in collecting my commission and only believed their agent's words. I wonder if there any way to register our complaints other than with the IEA, and how the IEA protects people like us. Chong Wei Yu", "pred_label": "__label__POS", "pred_score_pos": 0.6063193082809448} +{"content": "Dubai: Dubai Electricity and Water Authority (Dewa) has successfully concluded its ‘Let’s Make This Summer Green’ campaign. The drive, organised for the sixth consecutive year, has achieved remarkable success in raising customer awareness on adopting a sustainable and smart lifestyle to make a positive impact on the environment.\nThe campaign was organised under the theme ‘Create memories that last forever’ through Dewa’s social media, internal and external channels of communication. Dewa encouraged customers to use its services and innovative features on its website and smart app to monitor and control their electricity and water use, and get tips on reducing consumption.\nDewa’s conservation programmes and initiatives between 2011 and 2020 achieved cumulative savings within the target groups amounting to 2.44 TWh of electricity and 6.7 billion gallons of water, equivalent to saving Dh1.35 billion and reducing 1.22 million tonnes of carbon dioxide emissions.\nMost extensive digital campaign\nOver the last three months, Dewa’s employees led its most extensive digital campaign to conserve electricity and water in collaboration with public and private entities in Dubai. Dewa plays a pioneering role in promoting conservation in Dubai, with effective social campaigns to promote environmentally-friendly practices.\nThe campaign included the ‘Green Summer’ competition, being run until the end of September, for society members to save electricity and water. Participants can enter a raffle draw to win valuable prizes. Dewa also organised virtual and physical lectures for the educational, government, industrial and commercial sectors. Dewa’s Conservation Team presented 30 lectures and workshops in English and Arabic for its 3,151 employees and students across Dubai. During the campaign, Dewa collaborated with the Madrasa initiative, a Mohammed bin Rashid Al Maktoum Global Initiative, with videos for children to practise conservation during summer.\nRead more FNC Speaker Ghobash calls for international cooperation to counter terrorism, extremism Mohammed bin Rashid Humanitarian and Charity Establishment organises air bridge to Afghanistan Sheikha Fatima congratulates Razan Al Mubarak for being elected as IUCN president UAE among the first countries to address cybercrime, Saqr Ghobash says Dashboard to monitor consumption\nThe campaign highlighted the ‘Smart Living’ initiative for customers to monitor their consumption at home through their Dewa accounts on the website or smart app. Customers can easily check their dashboard to monitor consumption, know more about residential tariff slabs, get conservation tips and develop conservation plans. Customers can also benefit from the ‘My Sustainable Living’ programme to compare their consumption with similar homes in their area or use the Dewa Store to purchase energy and water-saving devices.", "pred_label": "__label__POS", "pred_score_pos": 0.721767783164978} +{"content": "On September 30th in Washington DC, Solve.Care and ARPI (American Research and Policy Institute) announced their intention to work together. They join efforts to address shortcomings in the Medicaid market specifically. It comes as a result of the increasing population in the United States. Inefficiencies in the Medical Field\nSolve.Care uses blockchain at a global level to streamline how healthcare is managed and delivered. On the other hand, ARPI is a non-profit academic research and policy organization situated in Washington DC. ARPI’s mission is dedicated to robust policy analysis and research for the public, policymakers and practitioners.\nAdditionally, their main focus lies with MMIS (Medicaid Management Information Systems) in individual states. Moreover, it marks integration with Centres for Medicare and Medicaid Services (CMS).\nA report by the United States Government Accountability Office for Congressional Requesters indicated the following. It stated an overall $44.1 billion from 2008 to 2018 spent for MMIS and CMS. Additionally, the report noted that the rising costs in Medicaid were due to inefficiencies and lack of oversight.\nWith the population increase across states, managing IT systems have become more complex. Hence interoperability, efficiency and securing data are more complex. The above-formed partnership seeks a solution to the impending state problem.\nBlockchain as a Solution in the Medical Sector\nThe combination of academic research and blockchain technology in addition to Smart Contracts is a way out. Moreover, they provide efficient data analysis, robust IT systems and proper management in the rising medical populations.\nFollowing the announcement, the CEO of Solve.Care Pradeep Goel showed his support for blockchain. In that, the technology offers a way to revolutionize how healthcare is managed. Also, when applied correctly, the Smart Contracts, DLT and Dapps provide a secure medium of sharing medical data.\nPradeep added that utilizing aspects of decentralized finance and the crypto ecosystem creates effectiveness and interoperability. Moreover, the complex IT protocols in blockchain could serve millions of beneficiaries across states. A tried example is NEMT (non-emergency medical transportation.\nAffordable Healthcare\nIn agreement was the Executive Director at ARPI, Dr David Randall. He insisted that projects like Medicaid offer healthcare to those who can’t afford it in his statement. However, the program is in much need of change to serve more Americans. If improved, it could save billions of taxpayer’s money.\nBoth ARPI and Solve.Care work hand in hand through research and use case applications for blockchain technology in medical care.\nRelated posts:\nSource: Read Full Article", "pred_label": "__label__POS", "pred_score_pos": 0.7110579013824463} +{"content": "The\navian flu It is transmitted from animals and humans through saliva, mucous membranes, and their feces. This dangerous infection, which has its point of similarity with the pandemic from Coronavirus, it can occur when the virus enters through a person’s eyes, nose, or mouth. The virus is usually present in the air and is inhaled by a person when they touch something containing the virus and then touch a hole in the body.\nAccording to experts, some human infections with some avian-influenced viruses have been recorded, most often after unprotected contact with infected birds or surfaces contaminated by avian flu.\nIn recent times, very few cases of the spread of bird flu from one person to another have been reported. Despite this, given the potential for avian flu to change and acquire the ability to easily infect people, monitoring human infections and person-to-person spread is vital to public health.\nWhat are the symptoms of type A bird flu?\nAs a general rule, the symptoms of bird flu in humans can be divided into mild and severe and included cases of conjunctivitis, flu-like illnesses, which are often accompanied by abdominal pain, nausea, diarrhea, vomiting, severe respiratory diseases, changes neurological and compromise other organs.\nAsian origin H7N9 viruses and HPAI Asian H5N1 viruses have been responsible for the majority of human cases infected with the virus to date worldwide, including most cases of severe illness and more. cases of death.\nHow is bird flu detected?\nAvian influenza cannot be diagnosed solely by clinical signs and symptoms, but requires laboratory testing. This is usually diagnosed by taking a sample from the upper respiratory tract (nose or throat) of the affected person.\nThis test is then sent to the laboratory, where any of the avian influenza A viruses will be looked for through a molecular test. In critically ill patients, taking specimens and samples from the lower respiratory tract may lead to the diagnosis of influenza A infection. However, patients who are not very ill or have already recovered, can be difficult to reach. to detect the virus.\nHow is bird flu cured?\nExperts recommend a neuraminidase inhibitor for the treatment of mild bird flu infections in humans. CDC released guidelines on avian influenza for healthcare professionals and laboratory personnel, including guidelines on the use of antiviral drugs to treat human infections with novel influenza viruses associated with other serious illnesses.\nThese analyzes of the virus have led to the conclusion that the virus is susceptible to oseltamivir, peramivir, and zanamivir. However, the antiviral resistance of the H5N1 and H7N9 viruses of Asian origin isolated from some cases in humans has been evidenced. Therefore, monitoring of antiviral resistance among avian influenza viruses is vital and continuous.", "pred_label": "__label__POS", "pred_score_pos": 0.548651933670044} +{"content": "Acute lung injury (ALI) most commonly occurs after severe bacterial infections such aspneumonia or sepsis. An clear impediment to successful ALI therapy resides in a complexdisease course often characterized by an initial burst in host inflammation from pro-inflammatory mediators resulting in extensive tissue injury; a second phase ofimmunosuppression ensues that poses risks for secondary bacterial infections. IL-1 ß,generated by the inflammasome and invasive bacterial infections both contribute to diseasepathobiology and illness severity. The mechanistic platform of this proposal resides on ourdiscovery of a unique molecular model of inflammation whereby a relatively new protein,Fbxo3, potently triggers IL-1 ß release from human inflammatory cells after bacterial infectionby destabilizing a crucial inflammasome inhibitor, Fbxl2. By targeting the ApaG molecularsignature present in both host Fbxo3 and many bacteria, we developed a first-in-class genusof small molecule inhibitors that display dual anti-inflammatory and anti-bacterial activity inmurine ALI models. Hence, in this application we will first elucidate how bacterial pathogenstranscriptionally activate Fbxo3, allowing the protein to eliminate an inflammasome inhibitor,Fbxl2 (Aim 1). We will specifically elucidate how Fbxl2 targets the NALP7 inflammasome.Next we will optimize the pharmacologic design and test a novel small molecule that exhibitsdistinct, and yet complementary anti-inflammatory and anti-bacterial properties in ALI models(Aim 2). These studies will provide a new mechanistic pathway of innate immunity that willserve as a basis to fulfill an unmet therapeutic need in subjects with altered immuneresponses during critical illness.", "pred_label": "__label__POS", "pred_score_pos": 0.962912380695343} +{"content": "We know that offering products that deliver a satisfying nicotine experience without burning tobacco or inhaling smoke — the primary link to diseases associated with smoking — is the right thing to do. We also know that one size does not fit all. Therefore, providing multiple alternatives, such as heat-not-burn, e-vapor or oral tobacco is necessary to meet the preferences of adult tobacco consumers and support them on their journeys. If we get this right, we can have a significant positive impact on public health and the health of individual smokers. And this is what I was trained to do.\nWe are investing in science to arrive at the right insights, guide product development and generate the data needed to really push the whole field forward. I'm excited by my work, and proud and humbled to work with world-class scientists, engineers, product development and regulatory affairs professionals who come to work every day committed to tobacco harm reduction. I firmly believe that the work that we do today will transform the tobacco industry and will have significant benefits for public health.", "pred_label": "__label__POS", "pred_score_pos": 0.8867360353469849} +{"content": "2Products found M1 Finance is a free finance app allowing you to invest, borrow, and spend in one platform. $0 account minimum. 100% commission-free trades and no hidden fees. Wealthsimple Invest helps you align your values with socially responsible investments through diversified and low-cost ETFs. No minimum balance, robo-advice, and access to financial advisors. Basic features include auto-deposits, auto-rebalance, and dividend reinvesting. Get a free portfolio analysis of your existing non-Wealthsimple portfolios.\nRetirement accounts are tax-advantaged and used to store and grow funds used during retirement which is defined by the IRS as after the age of 59.5 years old.\nRetirement accounts include: Employer-sponsored plans like 401(k)s offered as an employee benefit. 401(k)s allows you to contribute a portion of your pre-tax paycheck to tax-deferred investments. This reduces the amount of income you must pay taxes on that year. Individual Retirement Accounts offered by banks, credit unions, and investment companies. There are Traditional, Roth, and Rollover IRAs available and come with tax benefits. Additionally, small business owners may be eligible for SEP IRAs.\nYou can learn more about the different types of retirement plans with tax advantages through the IRS website.", "pred_label": "__label__POS", "pred_score_pos": 0.809506356716156} +{"content": "A recent New York Times’ article attacked American charities that help build communities in Israel’s West Bank and IRS policy that enables donations to these organizations to be tax-deductable. As with any piece about the Palestinian-Israeli conflict, many people have been quick to attack or defend the veracity of the article.\nTo nonprofit organizations, the value of the article is not the accuracy of the authors’ claims, but rather the article’s insight into current concerns and trends influencing the nonprofit sector. These can serve as warnings and guidelines to US charities that operate internationally.", "pred_label": "__label__POS", "pred_score_pos": 0.7667023539543152} +{"content": "Critically, it's time to admit that attributing the full value of the marketing investment to the last or \"converting\" click is fundamentally flawed. By ignoring all previous activities which have contributed to the eventual sale, this approach is inaccurate, untrustworthy and often results in investment in key activities being reduced or cut.", "pred_label": "__label__POS", "pred_score_pos": 0.9992899894714355} +{"content": "A research team led by associate professor, Mohammad Shehata at Toyohashi University of Technology, in cooperation with researchers at the California Institute of Technology and Tohoku University have found the brain waves and regions sensitive to team flow compared to non-engaging teamwork or a solo flow.\nThis study is the world's first attempt to study this psychological state objectively. These neural correlates not only can be used to understand and predict the team flow experience. The authors are working on utilizing the findings to monitor and predict team performance.\nDetails\nTeam flow is experienced when team players get \"in the zone\" to accomplish a task together. Great teams experience this psychological phenomenon, from sports to music bands and even professional work teams. When teamwork reaches the team flow level, one can observe the team perform in harmony, breaking their performance limits.\nIt is essential to reproduce this state in the lab and objectively measure it to investigate neural processing of team flow state, which has been an enormous hurdle for decades.\nResearchers at the Electronics-Inspired Interdisciplinary Research Institute (EIIRIS) at Toyohashi University of Technology and California Institute of Technology found ways to break such hurdles and provide first neuroscience evidence of team flow. The researchers measured the brain activity from 10 teams using EEG of teams of two while they played a music video game together. In some trials, a partition separated the teammates so they couldn't see each other while they played, allowing a solo flow state but preventing team flow.\nThe research team scrambled the music in other trials, which prevented a flow state but still allowed teamwork. The participants answered questions after each game to assess their level of flow. Moreover, the researchers invented an objective neural method to evaluate the depth of the team flow experience. Then, the researchers compared the brain activity of the participants during each condition. They found a unique signature of team flow: increased beta and gamma brain waves in the middle temporal cortex, a type of brain activity linked to information processing. Teammates also had more synchronized brain activity during the team flow state compared to the regular teamwork state.\nThis study will provide a framework based on neural models that can be utilized toward more effective team-building strategies in areas where human performance and pleasure matters - business, sports, music, performing arts, video games, and entertainment. In partnership with governmental and industrial institutions, the researchers plan to utilize the neural signature of team flow to monitor and enhance team performance and, perhaps, build more effective teams.\nEnhancing performance while maintaining enjoyment has many implications towards a better quality of life, including lowering the rates of depression, panic attacks, and anxiety.\nSource:\nJournal reference:\nShehata, M.,\net al. (2021) Team flow is a unique brain state associated with enhanced information integration and inter-brain synchrony. eNeuro. doi.org/10.1523/ENEURO.0133-21.2021.", "pred_label": "__label__POS", "pred_score_pos": 0.8434501886367798} +{"content": "Approximately 13% of patients with lung adenocarcinoma harbor the KRAS p.G12C mutation, which is associated with poor clinical outcomes. During the American Society of Clinical Oncology 2021 virtual annual meeting, Ferdinandos Skoulidis, MD, PhD, MRCP, Assistant Professor, Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, provided updated results from the phase 2 component of the CodeBreaK 100 clinical trial, which evaluated sotorasib (Lumakras), a small-molecule inhibitor of the KRAS p.G12C mutation, in previously treated patients with non–small-cell lung cancer (NSCLC) whose tumors express this aberration. These results were simultaneously published in the New England Journal of Medicine (2021 June 4. Epub ahead of print).\n“Sotorasib represents a breakthrough in targeted therapy for NSCLC patients with a KRAS p.G12C mutation. After nearly 4 decades of research, we now have an effective and well tolerated oral therapy against mutant KRAS—the most common driver oncogene in lung cancer,” Dr Skoulidis said.\nThe phase 2 part of the CodeBreaK 100 trial included 126 patients (median age, 63.5 years; 50% women; 81.7% white; 92.9% former or current smokers) with locally advanced or metastatic KRAS p.G12C–mutated NSCLC whose disease progressed on previous standard therapies. The majority of patients (81%) had previously received both platinum-based chemotherapy and PD-1 or PD-L1 inhibitors. Patients received sotorasib 960 mg/day until disease progression, death, or unacceptable toxicity. Radiographic scans were conducted every 6 weeks up to week 48 and every 12 weeks thereafter.\nThe primary end point of the study was overall response rate (ORR) according to RECIST v1.1 by independent central review. Key secondary end points included duration of response, disease control rate, time to recurrence, progression-free survival (PFS), overall survival (OS), and safety. Exploratory biomarkers were evaluated for their association with response to sotorasib therapy.\nAt a median follow-up of 15.3 months, the ORR among 124 evaluable patients was 37.1% (95% confidence interval [CI], 28.6-46.2), which included a complete response rate of 3.2% and a partial response rate of 33.9%. Median duration of response was 11.1 months (95% CI, 6.9-not evaluable). Median PFS was 6.8 months (95% CI, 5.1-8.2) and median OS was 12.5 months (95% CI, 10-not evaluable).\nSotorasib exhibited consistent and robust efficacy across patient subgroups defined by baseline clinical characteristics, including those aged ≥65 years (ORR, 44.1%), heavily pretreated patients (ORR per previous lines of therapy: two, 32.6%; three, 39.3%), and those who progressed on checkpoint inhibitors within the previous 3 months (ORR, 34.4%). Notably, the highest response rate was seen in patients who previously received PD-1/PD-L1 inhibitors but not platinum-based chemotherapy (ORR, 69.2%).\nIn an exploratory biomarker analysis, sotorasib demonstrated efficacy in molecular subgroups defined by co-occurring genomic alterations including STK11 and KEAP1, that are associated with poor outcomes with standard of care. Interestingly, patients with STK11-mutant but KEAP1 wild-type tumors appeared to derive increased benefit from sotorasib whereas KEAP1 mutations were associated with lower ORR. Due to the small number of patients, further study is needed to determine which subgroups derive differential benefit from sotorasib.\nSotorasib was well-tolerated, with 69.8% of patients experiencing treatment-related adverse events (AEs), most of which were grade 1 to grade 2 and manageable. No treatment-related deaths occurred as of data cutoff on March 15, 2021.\nThe most common treatment-related AEs of any grade included diarrhea (31.7%), nausea (19%), elevated alanine aminotransferase and aspartate transaminase (15.1% each), and fatigue (11.1%).\nGrade ≥3 treatment-related AEs occurred in 19.8% of patients, the most common being elevated alanine aminotransferase (6.3%) and aspartate transaminase (5.6%), and diarrhea (4%). Treatment-related AEs led to dose modifications and treatment discontinuation in 22.2% and 7.1% of patients, respectively.\nOn May 28, 2021, sotorasib received accelerated approval by the FDA for the treatment of adults with locally advanced or metastatic NSCLC with a KRAS p.G12C mutation, as determined by an FDA-approved test, following at least one previous line of systemic therapy.\nStay up to date with personalized medicine by subscribing to receive the free VBCC print publication or weekly e‑Newsletter.\nStay up to date on the matters of value in cancer by signing up for the free, bi-monthly VBCC print publication and VBCC weekly e‑newsletter.", "pred_label": "__label__POS", "pred_score_pos": 0.5991442203521729} +{"content": "In consideration of participating in Cross Country Skiing (Nordic), and for other good and valuable consideration, I hereby agree to release and discharge from liability arising from negligence the Wausau Nordic Ski Club and its owners, directors, officers employees, agents, volunteers, participants, and all other persons or entities acting for them (hereinafter collectively referred to as “Releasees”), on behalf of myself and my children, parents, heirs, assigns, personal representative and estate, and also agree as follows:\nI acknowledge that cross country skiing involves known and unanticipated risks which could result in physical or emotional injury, paralysis or permanent disability, death, and property damage. Risks include, but are not limited to slips, slides, and falls that might result in injury]; medical conditions resulting from physical activity; and damaged clothing or other property. I understand such risks simply cannot be eliminated, despite the use of safety equipment, without jeopardizing the essential qualities of the activity.\nI expressly accept and assume all of the risks inherent in this activity or that might have been caused by the negligence of the Releasees. My participation in this activity is purely voluntary and I elect to participate despite the risks. In addition, if at any time I believe that event conditions are unsafe or that I am unable to participate due to physical or medical conditions, then I will immediately discontinue participation.\nI hereby voluntarily release, forever discharge, and agree to indemnify and hold harmless Releasees from any and all claims, demands, or causes of action which are in any way connected with my participation in this activity, or my use of their equipment or facilities, arising from negligence. This release does not apply to claims arising from intentional conduct. Should Releasees or anyone acting on their behalf be required to incur attorney’s fees and costs to enforce this agreement, I agree to indemnify and hold them harmless for all such fees and costs.\nI represent that I have adequate insurance to cover any injury or damage I may suffer or cause while participating in this activity, or else I agree to bear the costs of such injury or damage myself. I further represent that I have no medical or physical condition which could interfere with my safety in this activity, or else I am willing to assume\n– and bear the costs of -all risks that may be created, directly or indirectly, by any such condition.\nIn the event that I file a lawsuit, I agree to do so solely in the state where Releasees’ facility is located, and I further agree that the substantive law of that state shall apply.\nI agree that if any portion of this agreement is found to be void or unenforceable, the remaining portions shall remain in full force and effect.\nBy signing this document, I agree that if I am hurt or my property is damaged during my participation in this activity, then I may be found by a court of law to have waived my right to maintain a lawsuit against the parties being released on the basis of any claim for negligence.\nI have had sufficient time to read this entire document and, should I choose to do so, consult with legal counsel prior to signing. Also, I understand that this activity might not be made available to me or that the cost to engage in this activity would be significantly greater if I were to choose not to sign this release, and agree that the opportunity to participate at the stated cost in return for the execution of this release is a reasonable bargain.\nI have read and understood this document and I agree to be bound by its terms.", "pred_label": "__label__POS", "pred_score_pos": 0.9082826375961304} +{"content": "Attorney General Bonta Leads Bipartisan Coalition in Defense of Indian Child Welfare Act Protections Before the U.S. Supreme Court OAKLAND – California Attorney General Rob Bonta today led a bipartisan coalition of 26 attorneys general in an amicus brief in support of the United States and four federally recognized tribes in their efforts to uphold critical protections guaranteed under the Indian Child Welfare Act (ICWA). Filed before the U.S. Supreme Court in Haaland v. Brackeen and Cherokee Nation v. Brackeen, the amicus brief highlights the states’ compelling interest in standing up for the well-being of all children, including Native American children, in state child-custody proceedings.\n“The truth is that there has been a long, ugly history in the United States of policies that had the effect of separating Native American children from their culture, families, and communities,”\nsaid Attorney General Bonta. “ICWA is a critical tool for protecting Native American children, their parents, and tribes — and it is under threat. If we are to truly honor the history and legacy of our tribal partners, we must act. Alongside a bipartisan coalition of attorneys general, that’s exactly what we’re doing. We’re urging the U.S. Supreme Court to hear this case and correct the errors the court of appeals made in its decision.”\nCongress enacted ICWA in 1978 in response to a serious and pervasive problem: State and private parties were initiating state child-custody proceedings that removed Native American children from the custody of their parents — often without good cause — and placed them in the custody of non-tribal adoptive and foster homes. That practice harmed children and posed an existential threat to the continuity and vitality of tribal communities. To address this, Congress established minimum federal standards governing the removal of Native American children from their families. ICWA’s provisions safeguard the rights of Native American children, parents, and tribes in state child-custody proceedings, and seek to promote the placement of Native American children with members of their extended families or with other tribal homes. In the four decades since Congress enacted ICWA, the statute has become the foundation of state-tribal relations in the realm of child custody and family services. Collectively, the coalition states are home to approximately 86% of federally recognized tribes in the United States.\nIn the amicus brief, the coalition asserts that:\nICWA is a critical tool for protecting Native American families and tribes, and fostering state-tribal collaboration; The court of appeals incorrectly concluded that several of ICWA’s provisions violate the anti-commandeering doctrine; and ICWA’s preferences for the placement of Native American children with other Native American families and foster homes do not violate equal protection.\nIn filing the amicus brief, Attorney General Bonta is joined by the attorneys general of Alaska, Arizona, Colorado, Connecticut, Idaho, Illinois, Iowa, Maine, Massachusetts, Michigan, Minnesota, Nevada, New Jersey, New Mexico, New York, North Carolina, Oregon, Pennsylvania, Rhode Island, Utah, Virginia, Vermont, Washington, Wisconsin, and the District of Columbia.\nA copy of the amicus brief is available here.\nSource: Office of the Attorney General of California", "pred_label": "__label__POS", "pred_score_pos": 0.7808654308319092} +{"content": "The Government of India, in collaboration with United Nations International Strategy for Disaster Reduction (UNISDR), hosted the Asian Ministerial Conference on Disaster Risk Reduction (AMCDRR) 2016 in New Delhi from 3-5 November 2016. The Delegations from 41 countries including Afghanistan, Armenia, Australia, Azerbaijan, Bahrain, Bangladesh, Bhutan, Brunei, Cambodia, China,Georgia, Indonesia, Iran, Japan, Jordan, Kazakhstan, Kiribati, Kyrgyzstan, Laos, Lebanon, Malaysia, Maldives, Mongolia, Myanmar, Nepal, New Zealand, North Korea, Philippines, Qatar, Republic of Fiji, South Korea, Sri Lanka, Tajikistan, Thailand, Timor-Leste, Turkey, Turkmenistan, Tuvalu, Uzbekistan, USA and Vietnam participated in the conference. Besides, few countries were represented through their respective Embassies stationed in New Delhi. No discussion was held specially on Asia-Pacific disaster mitigation in the conference. The Asia Regional Plan for implementation of the Sendai Framework for disaster risk reduction (2015-30), which was adopted during the conference, has provided a long term road map. It aims for implementation of priorities to achieve seven global targets of Sendai Framework.\nThe Conference concluded with the New Delhi Political Declaration, reaffirming the Government and stakeholders’ commitment to Disaster Risk Reduction. The declaration aims to:\ni. Recognize the opportunity to build on past achievements by reaffirming commitment to disaster risk reduction and resilience.\nii. Re-emphasize that the Sendai Framework for Disaster Risk Reduction is complementary to the 2030 sustainable development agenda.\nThis was stated by the Minister of State for Home Affairs, Shri Kiren Rijiju in a written reply to question by Shri Ranjib Biswal in the Rajya Sabha today.", "pred_label": "__label__POS", "pred_score_pos": 0.6228477358818054} +{"content": "Airport runways are named with numbers, but these figures are not given sequentially. It is all to do with orientation, and in the field of aviation, this is a critical factor.\nThe right direction\nAltogether, all runways are numbered based on the magnetic azimuth (compass bearing) in which it is is oriented. Each one is given a number that is between 01 and 36. There are 360 degrees on a compass rose. Therefore, the numbers are determined by rounding the compass bearing of one runway end to the nearest 10 degrees.\nHowever, Stantec highlights the last digit is dropped while each individual number is pronounced. For instance, a compass heading of 250 degrees would read 25 and would be spoken out loud as two five.\nMoreover, to simplify the process, aviation bodies such as the Federal Aviation Administration rounds headings to the nearest ten. Therefore, if a heading is 337 degrees, it’ll be named runway three four.\nRunways are also aligned primarily to make the most out of winds as they can assist with takeoffs and landings. Therefore, many large airports have an array of configurations to take advantage of seasonal wind changes.\nFurther additions\nNonetheless, some hubs are far busier than others. Subsequently, there are instances where naming conventions are taken to another level. For example, Presidential Aviation shares that airports with two parallel runways going in the same direction are designated as the left or right runway. These are marked with L and R. So, Runway 25 would be titled as 25L or 25R.\nMoreover, some airports have three parallel runways. In these instances, the third runway in the center will be given the designation of C. Therefore, Runway 25 would also have 25C if it had three parallel runways.\nAdditionally, even busier hubs often have four runways that are parallel, such as Los Angeles International Airport and Hartsfield–Jackson Atlanta International Airport. In these circumstances, the number for some of the names is shifted by ten degrees. So there would be a difference of a single digit.\nDallas-Fort Worth has five runways with the same heading. The east side’s runways are designated with L, R, C. Meanwhile, the west side’s have been increased by 10 degrees while using the designations of L and R.\nStandard requirements\nAbove all, every single public and military field across the globe should have runway designations permanently painted at the end of each runway. Furthermore, since English is aviation’s universal language, runways are displayed by the same numeric system.\nSo, if a flight is departing on Runway 36, the hub doesn’t have a whopping amount of 36 runways. This number is just based on orientation.\nWhat are your thoughts about how airport runways are named? Do you think that this is the best method for airports? Let us know what you think of the process in the comment section.", "pred_label": "__label__POS", "pred_score_pos": 0.5104769468307495} +{"content": "According to Bloomberg, Bayer AG will be blocked from selling the controversial dicamba-based herbicide in the U.S. after a federal regulators permit for the product was rejected by an appeals court yesterday.\nBayer spokesman Chris Loder said they strongly disagree with the ruling and are assessing their options. If the ruling stands, they will work to minimize any impact on their customers this season.\nIn its ruling, the appeals court acknowledged the “practical effects” of this decision, including the cost to farmers who have already purchased soybean and cotton seeds genetically modified to withstand dicamba and planted for the purpose of using the herbicide.\nThis ruling applies to the 2018 registration due to expire in December of this year. Bayer is working on a new EPA registration for the 2021 growing season and beyond.", "pred_label": "__label__POS", "pred_score_pos": 0.6909273266792297} +{"content": "The Washington Department of Financial Institutions (DFI) recently adopted final rules amending the regulations implementing the Washington Consumer Loan Act (WCLA) and the Washington Mortgage Broker Practices Act (WMBPA), effective November 24, 2019. The primary purpose of the revisions was to implement amendments to the federal SAFE Act authorizing temporary authority, though additional changes were made to the regulations in these final rules. The Washington DFI originally released the proposed rule amendments in August 2019.\nCertain key changes under the amended WCLA rules include:\nCertain key changes under the amended WMBPA rules include:\nOther changes under both the WCLA and WMBPA amended rules include, for example, reordering or moving of sections or specific language, the addition of citations, and various changes made for clarification purposes.\nIn addition to implementing temporary authority under the WCLA and WMBPA amended rules, the Washington DFI also announced the addition of several new statuses to be added to NMLS to support the new temporary authority, clarifying that, as of November 24, 2019, Mortgage Loan Originator (MLO) applications from certain individuals may qualify for Temporary Authority to Operate (TA) while the individual is meeting state application requirements. These statuses include:\nThe Washington DFI also provided some related guidance, including, among other things, that: (i) the evaluation of TA eligibility happens on any MLO application submitted on or after November 24; (ii) an individual must have a relationship with a company before the individual is TA eligible; and (iii) the company employing an MLO with TA is subject to both the federal SAFE Act as well as Washington state law to the same extent as if the MLO was licensed.", "pred_label": "__label__POS", "pred_score_pos": 0.8363728523254395} +{"content": "Passing an Inheritance to Your Children: 4 Factors To Consider\nParents often want to ensure their children’s future is secure by leaving them an inheritance. A\nsurvey from Ameriprise Financial found that 77 percent of parents intend to leave their children or grandchildren an estate. However, only 50 percent have made put plans in place to do so.\nPassing an inheritance requires considerable planning. You’ll need to prepare your estate in advance so that your children can receive their inheritance without any hiccups. Moreover, there are certain factors, like probate, you must consider before you begin estate planning. We usually recommend consulting a probate lawyer before you start your estate planning. In addition, hiring an estate law attorney to assist you with drafting your will and other essential documents is also an excellent idea.\nPassing Inheritance to Your Children\nOnce it’s time to pass inheritance, you need to ensure you’ve considered all the factors carefully. Some factors you should assess before leaving an estate include:\nManage Expectations\nWe recommend creating open lines of communication to ensure you can manage your children’s expectations regarding their inheritance. While sharing information with your children is necessary, it doesn’t mean revealing everything about yourself to them. Estate planning remains a parent’s decision. However, you can try bringing them into the fold by letting them know where they stand financially. Moreover, communicate clearly that their inheritance may change if you need the money for unforeseen medical costs. Finally, let them know essential information like where you keep the vital documents, the terms of the inheritance, etc.\nLevel the Playing Field\nIf you want to avoid your children squabbling among themselves after you’re gone, you should divide assets equally. Moreover, also ensure that you split responsibilities for managing your affairs as equitably as possible. Leaving your children with unequal inheritance can often cause them to harbor resentment towards you and toward each other. One method of avoiding such problems is to level the playing field.\nExplain Unequal Distribution\nIf you decide to divide your inheritance unequally, we recommend sitting your children down and explaining to them. Parents often leave unequal estate due to several reasons. For instance, one of your children may be a high-powered stockbroker working on Wall Street, while the other is a public-school teacher. Parents may leave a more substantial sum to the child with less money since they need it more. However, the likelihood that the other sibling understands the parent’s reasoning isn’t always apparent. Instead, your stockbroker child may harbor resentment because they might believe you care for your other child more. If you don’t wish to communicate with them, make sure to leave notes in your will explaining your decisions.\nUse a Trust\nIf you’re unsure about whether your children can handle their inheritance, consider using a trust. Many estate planners recommend creating a trust that distributes the assets in chunks. For instance, your trust may pay a portion of your estate when your children turn 25, and they may not receive the next share until they turn 40. Many estate law attorneys recommend using this approach to avoid your children blowing through their inheritance by spending recklessly.\nSeek Assistance Dividing Your Estate from a Legal Professional\nIf you’re considering leaving an inheritance for your children, we recommend seeking legal counsel immediately. If you’re seeking assistance with estate planning in NYC, we can assist you.\nThe law offices of\nLedwidge and Associates help clients plan their estates in Manhattan, Queens, and Brooklyn. Our attorney Joseph Ledwidge personally tends to clients seeking legal advice regarding probate and estate law. Contact us today to schedule a free phone consultation with us. RECENT POSTS categories Will Executor executor beneficiaries Will estate planning trusts Probate litigation incapacitation Will Execution Estate administration distribution of assets dispute heirs trustee administrator holographic wills living wills fraud valid will legal dispute wills death Executors & Fiduciaries Probate Will contest Will Contests blog Joint Accounts Divorce Legal separation Family lawyers", "pred_label": "__label__POS", "pred_score_pos": 0.9874557256698608} +{"content": "South Sudanese must assert their right and civic obligation to choose their own fate.\nThe Revitalized Agreement on the Resolution of Conflict in South Sudan (R-ARCSS), agreed in 2018, remains the most feasible foundation for peace in the nation and a source of optimism.\nIt has contributed to the country’s uncomfortable quiet. Unfortunately, the absence of political resolve to properly execute the deal, as well as its unpredictable execution, is dashing the expectations of many South Sudanese who have pinned their hopes on it as the most certain vehicle for restoring peace.\nThe peace accord’s key clauses involve public engagement in the constitution-making process, the transitional justice process, and the election of leaders after the transitional period.\nConstitution-making within the terms of the 2018 peace agreement provides an excellent opportunity to learn from previous mistakes and react to people��s demands while also inclusive and including all stakeholders.\nConstitution-making is fundamentally a battle over the allocation, redistribution, and restriction of power, and as such, is critical for peace and nation-building in a profoundly divided South Sudan.\nTo be sustainable, constitutional results must include and include people who have suffered injustice in developing new remedies. The constitution-making process provides an opportunity to rectify errors that occurred during the creation of the existing constitution.\nThus, increased representation, involvement, and participation of a diverse range of stakeholders, beyond those responsible for the current constitution or subsequent peace agreements, would be critical in capturing the aspirations of the South Sudanese and initiating the process of dismantling the status quo that has benefited only a few political elites.\nAs stated in Chapter 5 of the peace agreement, transitional justice issues have become even more important for South Sudan’s security and development. Since 2013, the conflict has claimed over 400,000 lives, and thousands have been subjected to severe human rights abuses.\nSouth Sudan’s planned transitional justice procedures and institutions are critical indicators of the political will to seek justice for victims of war and human rights abuses. This implies that if we achieve genuine justice and responsibility for human rights abuses and conflict, the victims must be at the heart of the transitional justice process.\nAs such, victim involvement enhances their voices to convert them into agents of transitional justice, leaders, and champions. This needs the organization and participation of victims and survivors of human rights abuses in the quest for justice and responsibility.\nFinally, election procedures allow people to influence the course of their nation by voting for their leaders. Elections provide an opportunity for political parties and civic organizations to recruit and organize supporters and to communicate alternative platforms with the public.\nElections also act as a catalyst for political discussion and public discourse since they are predicated on voter involvement.\nHowever, given the high stakes of elections in South Sudan and the apparent potential that elections may act as a catalyst for violent conflict, substantial measures to resolve areas of tension will be required throughout this transitional phase. The transitional government’s capacity to extend political and civic space will be critical in deciding the election’s legitimacy.\nAmong the actions required during this transitional period to prepare for elections that will unite South Sudanese are the following: reforming the National Security Service (NSS) to eliminate repressive elements and practices; amending the non-governmental organizations (NGOs) and NSS Acts to create a more enabling environment for civic actors to engage on issues of national importance.\nThus, the involvement of the South Sudanese people is critical to achieving the peace accord’s objectives. South Sudanese should not cede this responsibility to the present political leadership.\nThey must recognize that they both have a right and a civic obligation to help determine their country’s destiny by contributing to attaining the transitional processes’ objectives. South Sudan’s people must not outsource this vital task of nation-building to the present government.\nThey must take ownership of the transitional processes by participating in deciding their results for posterity and ensuring that the goals of the South Sudanese people are central to these processes.\nSouth Sudanese citizens must understand that there are no reserved dinner table places. And that they must insist on and grasp the right and chance to choose their future.", "pred_label": "__label__POS", "pred_score_pos": 0.6276462078094482} +{"content": "Abstract\nHIV Tat has been known to have multiple regulatory roles including replication of HIV and modulation of cellular kinases. We investigated whether signaling kinase PKR plays a critical role in mediating Tat-induced cytokine dysregulation. We showed Tat induction of IL-10 dysregulation is associated with PKR activation. To examine the mechanism involved, inhibition of PKR activity abrogated the Tat-induced cytokine induction. We next identified that the MAP kinases including ERK-1/2 and p38 are downstream of PKR in these Tat-induced pathways. Thus, PKR may play a critical role in mediating the subversive effects of HIV Tat resulting in IL-10 induction.\nPublication types Research Support, Non-U.S. Gov't MeSH terms CCAAT-Enhancer-Binding Protein-delta CCAAT-Enhancer-Binding Proteins / metabolism Cells, Cultured Cytokines / biosynthesis Cytokines / genetics* Cytokines / immunology Cytokines / metabolism* Dose-Response Relationship, Drug Extracellular Signal-Regulated MAP Kinases / metabolism* Gene Products, tat / metabolism* HIV-1 Humans Interleukin-10 / biosynthesis Interleukin-10 / genetics Interleukin-10 / metabolism Leukocytes / metabolism MAP Kinase Signaling System* NF-kappa B / metabolism Time Factors Transcription Factors / metabolism Up-Regulation eIF-2 Kinase / antagonists & inhibitors eIF-2 Kinase / immunology* eIF-2 Kinase / metabolism* p38 Mitogen-Activated Protein Kinases / metabolism tat Gene Products, Human Immunodeficiency Virus Substances CCAAT-Enhancer-Binding Proteins CEBPD protein, human Cytokines Gene Products, tat NF-kappa B Transcription Factors tat Gene Products, Human Immunodeficiency Virus Interleukin-10 CCAAT-Enhancer-Binding Protein-delta eIF-2 Kinase Extracellular Signal-Regulated MAP Kinases p38 Mitogen-Activated Protein Kinases", "pred_label": "__label__POS", "pred_score_pos": 0.807984471321106} +{"content": "BACKGROUND: The optimal type of ventilation in operating theatres for joint arthroplasty has been debated for decades. Recently, the World Health Organization changed its recommendations based on articles that have since been criticized. The economic and environmental impact of ventilation is also currently an important research topic but has not been well investigated.\nAIM: To compare how large, high-volume, laminar airflow (LAF) and turbulent airflow (TAF) ventilation systems perform during standardized simulated total hip arthroplasty (THA), as they pertain to colony-forming units (cfu), particle counts, and energy consumption.\nMETHODS: Two identical operating theatres were used to perform simulated THA. The only difference was that one was equipped with LAF and the other with TAF. Cfu and particles were collected from key points in the operating theatre, and energy was measured for each simulation. Thirty-two simulations were done in total.\nFINDINGS: LAF had significantly reduced cfu and particle count when compared with TAF, at both 100% and 50% air influx. Furthermore, it was shown that lowering the air influx by 50% in LAF did not significantly affect cfu or particles, although reducing the fresh air influx from 100% to 50% significantly lowered the energy consumption. Most simulations in TAF did not meet the cleanroom requirements.\nCONCLUSION: Cfu were significantly lower in LAF at both 100% and 50% air influx. It is possible to reduce fresh air influx in LAF operating theatres by 50%, significantly reducing energy consumption, while still maintaining cfu and particle counts below the ISO classification threshold required for THA surgery.", "pred_label": "__label__POS", "pred_score_pos": 0.9716595411300659} +{"content": "Does birdsong make us feel better?\nFEB 13, 2012: The impact of birdsong on our creativity and on our sense of wellbeing is to be explored in a three-year research project at the University of Surrey, supported by the National Trust and Surrey Wildlife Trust.\nThe study will examine the psychological impact of being exposed to birdsong, including whether it helps us relax, complete tasks and even think creatively. Researcher Eleanor Ratcliffe said: \"A great deal of anecdotal evidence suggests that we respond positively to birdsong. However, currently there is a lack of scientific research supporting the psychological effects of listening to birds.\"", "pred_label": "__label__POS", "pred_score_pos": 0.5594233870506287} +{"content": "Abstract\nAcquiring abstract Mathematics concepts is often challenging for young children. This study explored young children’s use of digital cameras to exhibit their understanding of the addition concept. It investigated how the processes involved in producing the photographs and creating the visual representation that helped to develop the children’s comprehension of the concept of addition. This study employed a qualitative research design and data collection included observation, dialogues with children and children’s artefact (i.e. photographs). Six children in a preschool centre were participants for the focus group. The findings showed that young children were capable photographers and that their visual representation images supported their understanding of the addition concept. The study implicated that the creation of mathematical visual representation is critical to facilitate the development of abstract mathematics concepts.", "pred_label": "__label__POS", "pred_score_pos": 0.6992847919464111} +{"content": "Ways the Brick Restoration Process Enhances a Home\nIf you live in a brick home, you may be considering restoring the brickwork. Bricks maintain an authentic look for heritage homes. Plus, they add character to a house, making it stand out from modern cement-render buildings. If you're wondering whether this kind of upgrade is worth it, consider the following ways brick restoration enhances a home. Structural Integrity A brick restoration makes a wall more secure and structurally sound. Over time, the mortar between bricks crumbles and falls away from a wall.", "pred_label": "__label__POS", "pred_score_pos": 0.9984603524208069} +{"content": "This research assessed the sustainability of protected area-based tourism systems in Nepal. The research was composed of three interrelated studies. The first study evaluated different approaches to protected area governance. This was a multiple-case study research involving three protected areas in Nepal: the Annapurna Conservation Area, Chitwan National Park, and the Kanchenjunga Conservation Area. Data were collected from various published and unpublished sources and supplemented with 55 face-to-face interviews. Results revealed that outcomes pertaining to biodiversity conservation, community livelihoods, and sustainable tourism vary across these protected areas. The study concluded that there is no institutional panacea for managing protected areas. The second study diagnosed the sustainability of tourism in two destination communities: Ghandruk and Sauraha, which are located within the Annapurna Conservation Area and Chitwan National Park, respectively. A systemic, holistic approach--the social-ecological system framework--was used to analyze the structures, processes, and outcomes of tourism development. Data collection involved 45 face-to-face semi-structured interviews and a review of published and unpublished documents. Results revealed that tourism has several positive and a few negative sociocultural, economic, and ecological outcomes in both communities. Overall, tourism has progressed towards sustainability in these destinations. The third study examined tourism stakeholders' perspectives regarding sustainable tourism outcomes in protected areas. The study compared the responses of residents with residents, as well as tourists with tourists, across the Annapurna Conservation Area and Chitwan National Park. Tourism sustainability was evaluated with six tourism impact subscales measuring negative and positive ecological, economic, and social impacts. Data were collected using the survey method. Respondents included 230 residents and 205 tourists in Annapurna, and 220 residents and 210 tourists in Chitwan. The findings revealed that the residents across these protected areas perceived positive and negative impacts differently, as did the tourists, suggesting that the form of tourism development affects the sustainability outcomes in protected areas. Overall, this research concluded that protected areas and tourism are intricately related, and sustainable management of a protected area-based tourism system requires a polycentric adaptive approach that warrants a broad participation of relevant stakeholders.\nDocument\nDescription", "pred_label": "__label__POS", "pred_score_pos": 0.7021431922912598} +{"content": "Jeremy, Ryan, and Maikel put their heads together to discuss infectious disease in terms of origins, detection, diagnostics, and containment. This conversation is particularly insightful as it touches on the economic implications at work in outbreak responses.\n1. Disease Reservoirs 2. Covid-19 Perspective 3. Antibiotic Resistance 4. Public Health 5. Ebola 6. \"Evolved\" diseases such as HIV 7. PCR Tests Questions, comments, and suggested topics can be submitted directly to Jeremy at [email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.9995181560516357} +{"content": "Purpose – The purpose of this paper is to prove that competitiveness of small‐ and medium‐sized enterprises (SMEs) among developing countries in the conflict regions will be enhanced through clustering. Design/methodology/approach – The study used quantitative and qualitative methods of research. Questionnaires were administered on a sample of SMEs working in food‐processing sector in Palestine, Jordan and Israel. Semi‐structured interviews were conducted with ten Palestinian SMEs to deeply understand the food‐processing cluster. The dependent variable “SMEs competitiveness” is measured by the balanced scored card while the independent variable “cluster” is measured by the “related and supporting industries.” Findings – The cluster and SMEs performance of food‐processing sector in Palestine is the lowest in relative to Jordan and Israel. The results show a significant positive relationship between cluster and SMEs performance in the Palestinian food‐processing sector. Practical implications – Cluster can help SMEs in the food‐processing sector in Palestine to enhance their performance. It has also been found that these SMEs need to build linkages among themselves and with related and supporting industries within the Palestinian territories, Jordan and Israel. Originality/value – The paper discusses the enhancement of SMEs performance working in a conflict region through clustering.\nEuroMed Journal of Business – Emerald Publishing\nPublished: Jul 1, 2014 Keywords: Competitiveness; SMEs; Clustering", "pred_label": "__label__POS", "pred_score_pos": 0.626251220703125} +{"content": "Self-denial doesn't exactly sound like a fun day at the park, especially when we talk about fasting. No one likes to be hungry, especially by choice. Well, believe it or not, fasting is a spiritual practice that helps us grow the character of Jesus. When we fast, it reminds us that we are ultimately dependent on God, and not ourselves or anything we eat, to sustain us. Likewise, it brings us into his presence as we remember he is all we really need.\nRichard Foster's\nguides us through the main spiritual practices God uses to shape us, including fasting. He offers a perspective that reveals that, while hunger can be inconvenient or cumbersome, fasting is actually a joy practice. We discover something better than the instant gratification we so often seek. We recommend Celebration of Discipline Foster'sentire book, but especially chapter four, on fasting.", "pred_label": "__label__POS", "pred_score_pos": 0.9924800395965576} +{"content": "Trust drives lockdown buy-in\nA new study suggests trust in scientists drives public support for pandemic restrictions.\nA massive study of 12 countries, including New Zealand and Australia, surveyed 54,000 respondents from March to December 2020.\nCombining this with experimental data, the researchers found that trust in scientists is the “key driving force” behind individual support for, and compliance with, public health measures like mask mandates and lockdowns.\nTrust in scientists was the highest in NZ, Austria, Canada, and the UK, followed by Australia, while the lowest trust was seen in France, Brazil and Poland.\nIn most countries, trust in scientists was a stronger correlate of compliance with efforts to reduce pandemic spread, as governments in many of the countries sampled during the period of data collection were actively and vocally against strong interventions (e.g. USA, Brazil), while others equivocated (UK).\nScientists, on the other hand, were more consistent.\nIn NZ, where the government has been consistent in advocating for stringent measures to prevent COVID-19 spread, trust in government has more effect on compliance than on average, whereas trust in scientists has below average effects.\nThe data suggests that trust in government was more influential in supporting compliance in NZ than in other countries, where messaging from government has been less consistent.", "pred_label": "__label__POS", "pred_score_pos": 0.9395251870155334} +{"content": "Description\nFor the 2.2% of all students identifying as in recovery from substance use disorder, an often overlooked and misunderstood resource for them is their on-campus disability services and accommodation staff. This lack of clarity regarding accommodations for students in recovery often also exists for the disability resource professionals serving them. In addition to knowledge gaps, stigma related to substance use disorder is often one of the greatest barriers for individuals seeking support. Understanding our responsibility to support this growing population and what accommodations may be most appropriate is the first move in ensuring these students have an equal educational opportunity. In this webinar, information regarding the complex relationship between substance use disorder and federal disability protections will be shared and recommendations for creating more recovery-supportive policies and procedures will be suggested.", "pred_label": "__label__POS", "pred_score_pos": 0.931227445602417} +{"content": "By reducing Australia’s dependence on electricity generated from coal, we not only reduce harmful CO² emissions into our air, we also reduce the demand on water that power companies require to generate this electricity. Currently, 130 billion liters of drinking water per year is used just to generate coal-based electricity.", "pred_label": "__label__POS", "pred_score_pos": 0.8881465792655945} +{"content": "Volvo announced it is recalling 460,479 older models globally for potentially defective driver-side airbags that have been linked to one death.\nThe vehicles involved in the recall are the 2001-2006 S80 sedan and the 2001-2009 S60 sedan according to the NHTSA’s safety recall report.\nThe recall includes about 259,383 vehicles in the U.S., 7,048 in Canada and 2,475 in Mexico.\nVolvo has identified the driver airbags containing FG2 Twin inflators with 5AT 148 N propellant as the issue. Propellant decay over time in certain conditions potentially resulting in critical inflator combustion pressures.\nIf the airbag inflator propellant tablets are subjected to elevated moisture levels and frequent high inflator temperatures, the tablets can start to decay and form dust particles. A higher burn rate can result in higher combustion chamber pressure and risk of inflator rupture.\nIn the event of an airbag activation, the driver may be struck by metal fragments from the inflator leading to serious injury or death.\nThe recall report states that the inflator manufacturer is German auto supplier ZF Friedrichshafen and Autoliv is the airbag assembly manufacturer.\nTo fix the issue, Volvo will replace the driver-side airbags with a more modern propellant and inflator for free.", "pred_label": "__label__POS", "pred_score_pos": 0.9976711869239807} +{"content": "Column Global Economy 2021.04.20\nIn this column series, Yukihiro Matsuyama, Research Director at CIGS introduces the latest information about aging, safety net and fiscal crisis in Japan with data of international comparison\nThe government enacted the Children and Youth Development Support Promotion Law in 2010 to tackle various problems, including domestic abuse, poverty, and youth unemployment. However, according to the data published in the Cabinet Office’s policy outline on April 6, 2021, the situation has worsened, as shown in Table 1.\nTable 1 Data on social issues related to children and teens\n(Source) Cabinet Office, The Policy Outline for Child and Youth Development Support Promotion\nAs shown in Table 1, the \"Relative poverty rate for children under 18\" dropped from 16.3% in 2012 to 13.5% in 2018, which seems to reflect an improvement. However, it is important to consider the following aspects:\n(1) In its Family Database, the OECD publishes the ranking of the \"Relative poverty rate for children under 18\" across 42 countries. The highest among the 42 countries was China (33.1% in 2011). However, Japan, which had a relative poverty rate of 13.5% in 2015, still scored higher than the OECD average (13.1%) and was consequently ranked 21st. Moreover, looking at the relative poverty rate of single-parent households, Japan scored 50.8% in 2015, making it the third highest after South Korea (56.6% in 2016) and Brazil (54.8% in 2013).\n(2) The rate is strongly affected by the direct impact of the recession on the poor. As mentioned in Column No. 302, Japan continues to suffer from medical collapse and economic stagnation due to the failure of the government’s measures against the COVID-19 pandemic, despite the relatively low number of infections. Furthermore, due to the significant delay in vaccination compared to other developed countries, social chaos in Japan might remain until 2022. Therefore, it seems inevitable that the relative poverty rate for children under 18 in 2021 will continue to rise significantly.", "pred_label": "__label__POS", "pred_score_pos": 0.6568442583084106} +{"content": "While funding sources for local roads and bridges has attracted attention during the interim and early session, MACo has focused on its core argument: the decades-old distribution of Highway User Revenues should be restored back to levels where it regains its status as the main engine supporting local roadway costs.\nAs reported by the Gazette, legislation was recently introduced by Senator Richard Madaleno to authorize local governments to impose up to a $20 vehicle registration fee to generate additional revenue for local transportation needs. According to a Task Force that recommended this as an option for funding local transportation, a $20 fee imposed by counties and cities would generate approximately $96 million in revenue. Under the bill, revenue raised by the fee would be matched by the State.\nMACo supports a different approach. “Transportation Funding Restoration” is the organization’s top priority for this session. With the recent expansion of transportation revenues, it is time for local governments to again play a more significant role in the State’s transportation funding plan.\nFor decades, local roadways were funded as one of the modes of transportation receiving 30% of Highway User Revenues (HUR). This percentage has been reduced to 9.6%. The average annual reduction since fiscal 2010 is $350 million. Cumulatively, this equates to approximately $1.75 billion in foregone revenue for local roadways.\nFor county governments, this has meant a remarkable cutback since FY 2009. The 23 county governments now share a meager $26.2 million in annual State funding for their entire road and bridge network. Simply put, no other component of the state budget has suffered a 91% cut like this.\nMACo is advocating for a funding strategy to be put in place this session to restore HUR. Two bills have been introduced to make this a reality.\nSB 664/HB 1067 , sponsored by Senators George Edwards and Richard Madaleno (a House companion bill is sponsored by Delegate Wendell Beitzel with multiple co-sponsors), would restore HUR over a three-year time frame back to 20% of the funding level received prior beginning in FY 2016. SB 765, sponsored by Senator Richard Colburn, would begin an immediate restoration back to 30% of HUR beginning in FY 2015. While the incremental strategy may be viewed as more reasonable, both approaches recognize that local governments have significant transportation needs that are not being met.", "pred_label": "__label__POS", "pred_score_pos": 0.800332248210907} +{"content": "Using many terms of your institution’s historical student data, the variables that are most predictive of student persistence at your institution are identified and used to create a\npersistence model. This model is used to deliver an individual persistence predictionfor each currently enrolled student. This prediction indicates the likelihood of a student enrolled in one term persisting to the next term at your institution and staying enrolled past your institution's census date (or add/drop period) or graduating.\nWhen an initiative is submitted to Illume Impact, these predictive variables are used to build a\npropensity model specific to that initiative. This propensity model assesses a student’s similarity to initiative participants and it is powered by the extensive set of variables in the Civitas data set that have historically been predictive of persistence at your institution. This ensures that when students are matched for comparison, the variables used are the factors most likely to influence whether these students persist.\nFor a given initiative at your institution (e.g. Freshman Writing Center), each student who meets the eligibility criteria to participate (e.g. first year student, enrolled full time) has a persistence prediction, as well as a\npropensity score. The propensity score measures the likelihood of a student's participation in treatment. For impact analysis using Illume Impact, propensity scores are determined by measuring the similarity of eligible students who did not participate in the initiative to students who did participate in the initiative.\nNext, students are\nmatched on these two dimensions - persistence prediction and propensity score. This two-dimensional matching ensures that the matched pair of students is similar in both their persistence likelihoods and their propensity to participate in the initiative. Each matched pair has one student who participated in the initiative and one student who was eligible but did not participate.\nAfter matching, the impact of the initiative can be estimated by measuring the overall difference between the persistence rate of the matched students who participated in the initiative and the persistence rate of the matched students who were eligible but did not participate in the initiative.", "pred_label": "__label__POS", "pred_score_pos": 0.9644035696983337} +{"content": "Making the transition to university can be a challenge. Besides extending your knowledge and developing new skills, you will also need to communicate in ways that reflect new approaches and values.\nAcademic Success will introduce you to the demands of university study in a clear and accessible way, and help you to understand what is expected of you.\nThis companion website features additional self-study activities for you to work through at your own pace, alongside a glossary of key terms and a sample chapter from the book.\nDownload sample chapter here.\nPraise for Academic Success:\n“This book delivers exactly what the title promises: everything a student needs to be successful in their studies. - Lee Fallin, University of Hull, UK\n“An invaluable guide to the nature of successful learning in a university context, which will help students better prepare for and manage the challenges faced in tertiary studies - Professor Jack Richards, University of Sydney, Australia\n“ Academic Success includes everything a new student needs to know about university: from how a university works through to advice on reading, writing and thinking academically, including differences between disciplines. It's a comprehensive, useful guide to transitioning to university and succeeding in your studies. - Helen Cooper, University of Birmingham, UK", "pred_label": "__label__POS", "pred_score_pos": 0.8193054795265198} +{"content": "We need to save our forests as we depend on forests for our survival, from the air we breathe to the wood we use. Besides providing habitats for animals and livelihoods for humans, forests also offer watershed protection, prevent soil erosion and mitigate climate change.\nOur focus will be on mangrove trees in Ras Al Khaimah", "pred_label": "__label__POS", "pred_score_pos": 0.6240121126174927} +{"content": "Abstract:\nCOVID-19 is an emerging viral infection of zoonotic origin that is closely related to the\nsevere acute respiratory syndrome coronavirus (SARS-CoV) that caused an outbreak in 2003. Therefore,\nscientists named the new virus SARS-CoV-2. On March 11, 2020, The World Health Organization\n(WHO) recognized COVID-19 as a global pandemic. At present, three vaccines have been approved\nor are being considered for approval by national regulatory agencies to immunize against COVID-\n19. However, the vaccines do not remain widely available, and no specific treatment against the virus is\navailable. The pathogenesis and proliferation pathways of SARS-CoV-2 are still not well known. Thus, in\nthis article, the saponin glycyrrhizin is discussed as a new potential therapeutic agent of natural origin (licorice\nroot, Glycyrrhiza glabra) for the potential treatment of COVID-19 infections.", "pred_label": "__label__POS", "pred_score_pos": 0.957741916179657} +{"content": "The increasing adoption of light-emitting diodes (LEDs), increasing demand for customized smart homes, reducing prices of LEDs, development of smart cities, and upcoming mega projects are the major growth drivers for the Saudi Arabian lighting market. Due to the aforementioned factors, the industry is projected to generate $3,577.0 million revenue in 2030 and advance at a CAGR of 10.2% during 2020–2030.\nDuring COVID-19, preventive measures, such as lockdowns and import barriers, led to a significant decline in the growth rate of the market for lighting in Saudi Arabia. This was because of the postponement of commercial and industrial projects in the country. Moreover, the low availability of raw materials for manufacturing light casings and chips affected product supply. However, the industry is recovering in 2021, having already recorded significantly higher sales than in 2020.\nThe lighting market in Saudi Arabia is categorized into fixture and control, based on component. Of these, the fixture category dominated the market during the historical period (2015–2020). Further, the category is likely to retain its position during the foreseeable future owing to the large number of ongoing construction projects to meet the country’s 2030 target. Further, the lowering cost of LED and organic light-emitting diode (OLED) fixtures is encouraging more individuals to spend on lighting products.\nMoreover, the market for lighting in Saudi Arabia is categorized into wired and wireless, based on technology. Out of these, the wireless category is projected to showcase the faster growth during the forecast period (2021–2030). As such lights do not require wires, users can position them specifically to save energy and money. This is because these systems can be installed at greater distances than allowed by wired variants.\nPlayers in the lighting market of Saudi Arabia are involved in product launches to gain a significant position. For instance, in April 2019, the latest collection of distribution boards, cables and wires, switches and sockets, switch and junction boxes, service boxes, and lighting products was launched by Alfanar Group at the IEE Conference.\nMajor players operating in the lighting industry of Saudi Arabia are Al Nasser Group, LEDVANCE GmbH, Alfanar Group, NVC International Holdings Limited, OPPLE Lighting Co. Ltd., CINMAR Lighting Systems, Huda Lighting, Al AbdulKarim Holding, Zumtobel Group AG, Signify N.V., TRILUX GmbH & Co. KG, and National Lighting Company.", "pred_label": "__label__POS", "pred_score_pos": 0.9443418383598328} +{"content": "By Bo Wandell, President of AnswersAnywhere\nThe Digital Transformation has marked a radical rethinking of how field service organization use technology to do business. Simply “getting by” with outdated technology is not a viable option for any company that wants to stay competitive and profitable.\nDespite this rapid digital acceleration, one holdover from the Jurassic period still remains: the PDF.\nThe PDF is Not Fit for Human Consumption\nPDFs were created in 1993 and it shows.\nIn this digital era, PDFs are unfit for human consumption. PDFs are linear and limiting, outdated and clunky. This is even more true for the millennial user who has grown up viewing information on web browsers and mobile devices.\nPDFs take a painfully long time to load, particularly if they’re large files (I’m looking at you, service manuals). It’s also impossible to update them after they’ve been published, and once distributed, it’s impossible to recall them. This make it near impossible for an organization to ensure their technicians are all working with the most updated information.\nAdditionally, PDFs are difficult to navigate because users have no quick way of getting to the information they need. Search functions are limited, there’s no way to return to previous sections and even clickable table of contents require users to scroll all the way back up to the top if they want to navigate somewhere else in the document. Consider how tedious this would be with a 200-page service manual.", "pred_label": "__label__POS", "pred_score_pos": 0.5816587805747986} +{"content": "A linear relationship between CPB time and postoperative AKI was observed. Adjusting for adjusted for age; gender; BMI; smoking history; aortic cross clamp time; nasopharyngeal temperature at circulatory arrest; combined with aortic bypass surgery; AMI; intraoperative transfusion of PRBCs; renal artery dissection or occlusion; Penn class; kidney malperfusion; preoperative shock; Bentall+TAR+FET. In this figure, the red line indicates the estimated risk of acute kidney injury, and the dotted lines represent pointwise 95% CI", "pred_label": "__label__POS", "pred_score_pos": 0.5714842081069946} +{"content": "Charitable fundraisers frequently announce giving by others, and research shows that this can increase donations. However, this mechanism may not put information about peers to the most efficient use if it is costly to inform individuals who are indifferent to peer actions or causes some individuals to give less. We investigate whether a simple mechanism without incentives can predict heterogeneity in charitable responses to peer decisions. We elicit beliefs about donations in a baseline solicitation, and in subsequent solicitations we randomly assign information about others’ donations. We find that elicited beliefs are often logically inconsistent and that many subjects fail to update beliefs when treated. However, elicited beliefs can predict heterogeneous treatment effects if individuals are engaged and the information is salient.\nOriginal language English (US) Number of pages 41 State Published - Jan 28 2021\nName CESifo Working Paper No. 8855", "pred_label": "__label__POS", "pred_score_pos": 0.6378581523895264} +{"content": "Computerized order sets for medication management were recently shown to be associated with increased patient safety risks in primary care setting. This study was aimed at demonstrating similar phenomenon in a hospital setting. After introduction of computerized order set targeting hypoglycemia, the frequency of hypoglycemia significantly decreased from 1/1/07 to 12/31/08. However, the frequency of hyperglycemia also increased at the same time from 1/1/07 to 12/31/07. Only after subsequent introduction of a hospital-wide standardized insulin order set including hyperglycemia policies, the frequency of hyperglycemic episodes declined. Hypo/hyperglycemia is associated with adverse clinical outcomes in the inpatient setting. Retroactive analysis showed that if hypoglycemic and hyperglycemic policies were introduced simultaneously, unexpected increase in frequency of hyperglycemic episodes could have been avoided. These data are informative in identifying unanticipated consequences of an insulin management order sets focused entirely on hypoglycemia. A balanced approach in implementing insulin management EMR order sets that concurrently addresses both hypoglycemia and hyperglycemia policies is warranted.", "pred_label": "__label__POS", "pred_score_pos": 0.5401371717453003} +{"content": "TITLE:\nCharacterisation of Early Age Deformations in Cement Paste: Case of Chemical and Autogenous Shrinkage\nAUTHORS:\nNkwenti Flavious Tanue, Tubuo Fabian, Fokwa Didier, Tchemou Gilbert\nKEYWORDS:\nAutogenous Shrinkage, Chemical Shrinkage, Volumetric Deformation, Water-Cement Ratio\nJOURNAL NAME:\nJournal of Minerals and Materials Characterization and Engineering,\nVol.8 No.4,\nJuly\n21,\n2020\nABSTRACT: Concrete is commonly seen as a durable and long-lasting construction\nmaterial. However, the long-term performance of a concrete structure can be\ngreatly compromised by early-age cracking. This work is an experimental\ncontribution to study early age deformations of cement paste. Its aim is,\nfirstly, to develop an experimental dispositive for assessing chemical and\nautogenous shrinkage, and secondly, to measure these volumetric deformations in\ncement paste. The setup was done following the gravimetric method of\nmeasurement, which exploits the Archimedes’ principle. It is made up of an\nelectronic balance, a data accusation unit, a temperature control unit and a\nbuoyancy bath. Investigations were done on Portland cement (CPA-CEM II) at the\nfollowing W/C ratios: 0.25, 0.3, 0.35, 0.4 and 0.5. It was noticed that the\nwater-cement ratio does not influence the magnitude of the chemical shrinkage\nin a significant manner but had a kinetic effect; a lower W/C induces a faster\nrate of chemical shrinkage. Autogenous shrinkage was discovered to be highly\ninversely proportional to the W/C and was also noticed to be in a function of\nchemical shrinkage within the first 2 to 4 hours when the paste was still\nliquid.", "pred_label": "__label__POS", "pred_score_pos": 0.8184835910797119} +{"content": "This Management and Leadership training course aims to encourage effective, collaborative methods of leadership and management. This comprehensive training course helps delegates to work in their organizations and leverage the leadership potential of team members. Delegates will be exposed to focus on developing leadership skills, personal influence, as well as explore strategies for building a team of strong professionals who will support each other, deal with tough problems efficiently, and take accountability. This training course focuses on tactful leadership practices that are effective in any business. This training course also offers a comprehensive overview of good management practice for those new to supervision. This training course introduces delegates to the variety of skills needed to be successful and offers insights into how to personally manage the transition from being a ‘technical expert’ to supervision and team management. If you are new to supervision or management this course offers a compendium of ideas which will impact your practice immediately.\nLearning outcomes By the end of this training course, participants will be able to: Discover the core competencies required for exemplary leadership Examine the ethical aspects of leadership and values which drive lasting results Appraise and select supervision tools that track performance Comprehend and utilize the value of the performance management process Create and monitor personalized action plans for self, others and the team", "pred_label": "__label__POS", "pred_score_pos": 0.9873459339141846} +{"content": "On October 5, 2021, California Democratic Gov. Gavin Newsom signed A.B.\n1200, which bans per- and polyfluoroalkyl substances (PFAS) in paper-based food packaging by January 1, 2023, while requiring cookware manufacturers to begin disclosing PFAS and other toxic chemicals used in their products by 2024. The bill also requires manufacturers to use “the least toxic alternative” when replacing PFAS in the food packaging.\nThe governor also signed California A.B.\n652, which prohibits the use of PFAS in “[j]uvenile products,” such as infant carriers, infant seats, cribs, strollers, and any other “product designed for use by infants and children under 12 years of age,” starting on January 1, 2023.\nCalifornia follows the lead of Connecticut, Maine, Minnesota, New York, Vermont, and Washington, which have all taken similar measures in regulating PFAS in consumer and children’s products in recent years. While many environmental groups celebrate the California governor’s actions, it remains to be seen if manufacturers affected by these bills will challenge their enactment.", "pred_label": "__label__POS", "pred_score_pos": 0.6391993761062622} +{"content": "Programme aims\nThe programme aims to equip graduates with an informed and critical knowledge base of mental health in children and young people.\nThe aims of the MSc Mental Health in Children and Young People: Psychological Approaches are:\nTo develop a comprehensive understanding of interacting factors that promote good mental health across the life span from infancy to young adulthood To explore critically how interacting factors can lead to risk for mental health conditions To provide a thorough understanding of developmental theories and how they apply to children and young people in practice. To develop a theoretical and applied understanding of specific issues such as attachment theories, parenting and trauma and how they translate to practice settings.. To explore the evidence base for a wide range of psychological therapies as applied to children and young people.\nWhat our students say:\nFocusing on the importance of evidence-based interventions and the ability to critically evaluate the extant literature, I feel this MSc has equipped me with strong tools for my future career in the field of psychology\n(Aigli Raouna, graduate 2016)\nThroughout the variety of courses offered, I have gained invaluable skills, including conducting literature reviews, data analysis, report writing and public speaking and engagement\n(Kirsty Macmillan, graduated 2017)\nMy past experience consists mainly of working in early childhood settings with children from vulnerable populations. This approach of the programme has allowed me to connect my learning in children and young people’s mental health to my specific area of practice\n(Amelia Austin, graduated 2017)", "pred_label": "__label__POS", "pred_score_pos": 0.9372363686561584} +{"content": "Abstract\nWe have used spin-trapping techniques to identify radical species formed during the NADPH-stimulated peroxidation of rat hepatic microsomes. Using 5,5-dimethyl-1-pyrroline-1-oxide, we have confirmed the presence of substantial quantities of superoxide but found evidence for the formation of only small quantities of hydroxyl radical. Use of the spin traps N-tert-butyl-alpha-4-pyridylnitrone-1-oxide and 2-methyl-2-nitroso-1-propanol have allowed us to determine that lipid peroxyl radicals are the predominant \"lipid-type\" radical found in peroxidizing microsomes under aerobic conditions. These data suggest that microsomal lipid dienyl radicals react with molecular oxygen at near diffusion-controlled rates.", "pred_label": "__label__POS", "pred_score_pos": 0.9332188963890076} +{"content": "Health is one of the most fundamental things that should not be overlooked within a household. When one member of a family is sick, everyone in the family suffers. Therefore, a healthy lifestyle should be promoted at home. Whatever role you have in the family, whether you’re the wife, husband, father, mother, son, or daughter, […]\nNumbers are rising every day, in terms of people getting infected and dying of COVID-19. We have seen it in the news. This pandemic must be taken seriously. We are battling a deadly virus that we cannot see. The worst part is the vaccine yet to be made. However, we can do something. We all […]", "pred_label": "__label__POS", "pred_score_pos": 0.8011329174041748} +{"content": "My submission to Parliament’s inquiry on the introduction of congestion pricing to Auckland. I argue strongly in favour of introducing such a system.\nThe New Zealand Parliament’s Transport and Infrastructure Committee recently requested submissions on proposals to introduce congestion pricing to New Zealand’s largest city and my previous home city, Auckland. Given my current residence in Singapore, which was one of the first cities in the world to adopt a system of congestion pricing, I felt I was ideally placed to submit to the inquiry. I concluded that:\nThe Committee, if it takes its responsibility to provide quality infrastructure to New Zealanders seriously, should recommend the immediate implementation of congestion charging in Auckland.\nI applauded the proposal on three grounds:\nFurther, I rebutted the oft-repeated objection that congestion charging would be ineffective or unfair given the current state of Auckland’s public transport system.", "pred_label": "__label__POS", "pred_score_pos": 0.9181919097900391} +{"content": "Smart Transport exclusive article\nThe Norfolk Car Club is a Community Interest Company with 60 cars in Norwich, a city of 141,000. This is an exceptional sized car club outside London; in contrast, Derby is served by a mere five car club vehicles.\nThe success of the car club has hinged on investment, including funding from the local council, DfT and contributions from S106 agreements (private agreements between local authorities and developers). This has enabled the car club to provide a network of vehicles and expand as demand increases.\nThis demand is created because parking is controlled. Norwich has central parking restrictions because, historically, parking demand has been high and has created pressure on the streets for both residents and businesses.\nHowever, the car club has been allocated on street parking for its vehicles as it has grown, with space allocated whenever it has met certain metrics. In addition, S106 agreements have been used to ensure development supports the car club (and is less favourable to car ownership).\nMarketing has been consistent, long-term and well-targeted, recognising that people rarely make a snap decision to join the car club. It has used both traditional and social media, and has also targeted streets surrounding cars with targeted leaflet drops.\nThe key messages have been around saving money, easy parking and 24/7 availability.\nThis has been successful. Norfolk Car Club grew by 36% in the first eight months following DfT investment, with nearly 250 new members joining. It also saw a 25% increase in the number of bookings of vehicles.\nThe car club has been proactive in creating a network of cars so that they are perceived as a realistic alternative to ownership without the stress of finding parking spaces.\nAs the network has grown, the car club has noted a greater enthusiasm for member-to-member recruitment. Perceived availability has been key to this rise in member marketing.", "pred_label": "__label__POS", "pred_score_pos": 0.9934900403022766} +{"content": "Help Manage Your Dental Practice's Risk with Life Insurance for Buy/Sell Agreements\nLife insurance policies for buy/sell agreements are opportunities to provide your dental practice with stability and continuity in the event of a managing partner's untimely death.\nThis kind of agreement allows you and your partners to determine what happens to one partner's shares in a company if they pass away unexpectedly. That way, there's a plan in place in case of a partner's unexpected and tragic passing.\nPlanning for Your Practice, Partners, Employees, & Family\nEnsure your practice, partners, employees, and family receive the equitable treatment they should get with a life insurance policy for a buy/sell agreement.\nThis kind of strategic planning can help protect the legacy of your career, the legacy of your partners, the integrity of your practice, and more. It can also prevent future friction points among your partners or between your business and surviving family, ensuring everyone is aware of and receives the appropriate recompense following your death.\nThis kind of policy may be challenging to discuss with your partners and even harder to discuss with your family. However, it can help ensure the continued life of your dental practice while reducing the stress of your passing among those in your life.\nLife Insurance for Buy/Sell Agreements at a Glance\nLife insurance for buy/sell agreements may help with the following:\nPurchasing a deceased partner's shares of a business Ensuring a partner's family receives proper recompense for the business shares Establishing a pre-determined price for partner shares Preventing unplanned inheritance of practice business shares Reducing the stress of a partner's passing on their business and family Request a Free Consultation to Learn More about Life Insurance for Buy/Sell Agreements Other Featured Services Entity Malpractice Coverage\nProtect your practice in malpractice lawsuits.\nProfessional Liability Malpractice Insurance\nProtection from malpractice lawsuits.\nBusiness Owner's Protection\nProtection from major property and liability risks.\nWorker's Compensation\nBenefits for staff members injured on the job.", "pred_label": "__label__POS", "pred_score_pos": 0.6574118137359619} +{"content": "Project description Does biopsy and surgery induce cancer metastasis?\nCancer diagnosis and treatment often involves biopsy and/or surgical removal of the primary tumour leading to tissue injury. Metastasis, the leading cause of cancer-related deaths, is often initiated by single cells delivered from the primary tumour through the blood stream. This EU-funded project will investigate whether initial tissue injuries significantly contribute to blood-borne dissemination of tumour cells leading to metastasis formation. The research will focus on breast cancer and prostate cancer. It will investigate the impact of the release of circulating cancer cells after biopsy or surgical intervention, and apply novel technologies to capture circulating cells for their functional analysis. Additionally, they will assess therapeutic strategies to prevent the dissemination of viable cancer cells to distant sites.\nFields of science Topic(s) Call for proposal\nERC-2018-ADG\nSee other projects for this call", "pred_label": "__label__POS", "pred_score_pos": 0.9998425841331482} +{"content": "Tesis\nChance: the unpredictable in Paul Auster’s works Date2005 Author\nMateluna Astorga, Carolina\nInstitutions Abstract\nChance is a key figure in our daily lives, since we are uncertain about events in our future that may affect our health, economic stability, or personal interactions. It comes, therefore, as no surprise that chance affects a human life deeply -- as deep as a person's convictions, beliefs, and other matters central to someone‟s life-plan. If she had not missed her train, she would never have met her spouse. Had she lived in other times, she may have been a black slave in Georgia instead of an American citizen with equal rights.", "pred_label": "__label__POS", "pred_score_pos": 0.9760391712188721} +{"content": "You can find below materials from reliable sources related to the ongoing Coronavirus (COVID-19) pandemic. Use the tags to navigate and find the information you need. Use the links on the right column to access larger hubs.\nThe world is currently facing trying times, with a pandemic that threatens the fabric of society. Once again, we see that for challenges of this scale, there is an ever-increasing need to understand and connect efforts, and collaborate across a broad scale of stakeholders to combat this challenge.", "pred_label": "__label__POS", "pred_score_pos": 0.9999603033065796} +{"content": "Nanobubble technology, a nonchemical disinfection method that involves injecting ultrafine bubbles of a chosen gas (each with its own disinfection properties) into water, is transforming wastewater treatment industries around the world.\nAn IDRC-funded project in Asia found that distance education can be as effective as traditional face-to-face education in delivering quality teaching and a good learning experience. This finding is particularly significant for remote and resource-poor regions in countries such as Mongolia and Cambodia. The project underscored the importance of choosing appropriate technologies and mediums of distance education based on learner needs, capacities, and the socio-economic context.", "pred_label": "__label__POS", "pred_score_pos": 0.9762091636657715} +{"content": "Course Details\nThis course covers theories from different psychological perspectives on defence mechanisms affecting all people. These theories are then integrated with skills for addressing defensiveness in conflict situations. You will also explore how face-saving affects defensive behaviours. Defensiveness is behaviour for protecting oneself from a perceived threat or attack. In negotiations and mediations it can create major barriers but, when explored, it can open up opportunities for breakthroughs. When people are defending and protecting their self-image (face-saving), listening becomes more difficult and positions become entrenched. Left unaddressed, defensiveness can stalemate the discussion. You will have the option to record your role-play on the final day of the course.\nCRES-1170 or CRES-1180 Prerequisites\nCourse Offerings\nNo sections are currently scheduled for this course", "pred_label": "__label__POS", "pred_score_pos": 0.5275412797927856} +{"content": "Exhibits 1.34-1.36\nUntil this year, the more dealers who participated in our Survey, the lower the percentage that offered managed IT. We believe the reason for this trend can be attributed to the number of smaller dealerships with revenues under $5 million completing the Survey.\nAfter hitting a high of 50% of Big Six dealers declaring they offered managed IT in 2018 with 330 dealers participating, we saw that percentage decline as participation in the Survey climbed. In 2019, the percentage of the 344 dealers offering managed IT declined to 46%. Last year, the percentage of dealers offering managed IT declined to 44%. This year, somewhat surprisingly, there was an increase in the percentage of dealers offering managed IT (46%), despite the number of Survey respondents increasing. Exhibit 1.34 shows just how much the percentage of engagement has increased since last year among dealers representing the Big Six.\nNo matter what the percentage, managed IT has a bright future in the channel. Most larger dealerships with revenues over $10 million offer managed IT. It’s a natural addition to a dealership’s services offerings, especially with so many devices connected to the network. Other factors that will impact its growth are expanding the network beyond the traditional workplace as more employees work remotely and a growing awareness of network security. Security is a critical component of any managed IT offering and a way to get a foot in the door. What customer doesn’t want to make their network, data, and business more secure from outside threats? Dealers that offer managed IT have an inside position on the security talk track.\nSimply put, managing a customer’s network broadens and enhances a dealer’s product and services offerings. With the introduction of new product offerings such as smart offices and smart meeting rooms, the ability to manage a customer’s network is taking on greater importance for dealers interested in offering those services.\nTracking managed IT engagement by dealers representing the Big Six OEMs, everybody was up from the previous year, with Konica Minolta and Canon dealers leading the pack at 59% and 58%, respectively. Though Canon has only 37 Canon dealers participating in the Survey, this OEM saw its dealers’ managed IT engagement grow by 13%. We used to think that Konica Minolta’s All Covered division was one of the reasons why such a large percentage of Konica Minolta dealers offered managed IT, but for the past couple of years, Survey results don’t seem to back up that argument. Last year, 15 of the 29 Konica Minolta dealers that offered managed IT said they partner with a third-party (more than likely All Covered), while this year, only six of the 21 Konica Minolta dealers that offer managed IT partner with a third-party. Considering the investment Konica Minolta made when it acquired All Covered in 2011, and the ongoing recognition All Covered receives in the IT world, one would expect more Konica Minolta dealers would be partnering with this division. We could chalk this up to dealers’ entrepreneurial spirits, where many would simply prefer to build it themselves, as we continue to see in our Survey findings.\nIndeed, there are three primary ways a dealer can build a managed IT business, and as our Survey reveals, the least popular way to do so is through acquisition (Exhibit 1.38), with 12% of respondents using this strategy, compared to 19% in last year’s Survey. The most popular method is building their own (61%). Some dealers identified multiple strategies for building their managed IT business, so the cumulative percentages in Exhibit 1.36 do not equal 100%.\nAs dealerships have become more proficient at installing network devices, the confidence level in starting their own managed IT business has likely accelerated, as has access to IT professionals who are more likely to switch jobs for the right offer. However, connecting an MFP to the network is very different than managing a customer’s computer network. The challenge for many dealers is the cost of hiring this talent. Dealers often lament the cost, but some now realize that they can’t have a successful and sustainable managed IT business if they don’t invest in the personnel to staff it. With more dealers diversifying into unified communications and physical security systems, both of which fall under the managed IT umbrella, the need to invest resources into managed IT has become more critical than ever.\nWe remain skeptical about the percentage of revenue from managed IT reported by manufacturer (Exhibit 1.35). This year’s average is 11.8%, which is up from 9% a year ago, and 8% two years ago. Even then, we felt those percentages were higher than they should be based on our conversations with dealers and organizations that track managed IT revenue based on dealers’ actual financial reports. Despite this, we must still adhere to the honor system with our Survey respondents. The top percentages by manufacturer were up from the previous year with Toshiba (13%), followed by Konica Minolta, Kyocera, and Ricoh at 12%. Canon and Sharp dealers reported average revenues of 11%. Those increases could be attributed to setting up customers’ employees remotely in 2020.\nLast year, for the first time, we asked dealers if managed IT revenues were up, down, or the same compared to the previous year. Fifty-one percent of respondents reported revenues were up, while 38% reported revenues were the same as the previous year, and 11% experienced a decline in their managed IT revenues. Comparing these percentages to last year, 62% of respondents reported managed IT revenues were up, 35% reported revenues were the same, and only 3% said that revenues were down. We do not need to dig too deeply to identify the reason why fewer dealers reported revenues were up and more reported revenues were down. If we must state the obvious, we will—the pandemic.\nAccess Related Content", "pred_label": "__label__POS", "pred_score_pos": 0.7863256335258484} +{"content": "People who want to let go of unwanted fat from specific areas of their body are usually limited to a few treatment options. Somehow, if you work with a professional workout trainer, high-intensity workouts and a strict diet are effective. Still, they will not result in fat loss targeted in the area of concern unless you follow a specific protocol. Your next option could be liposuction, which can be both expensive and invasive. Therefore, it wouldn’t come as a surprise that many people choose to do nothing and just attempted to conceal their bulges. Some would just struggle with their insecurities in solitude. Fortunately, a revolutionary new treatment called Cryo Slimming has recently been developed. So, does it really work? How is it done? Let’s find out!\nWhat is CryoSlimming?\nCryo Slimming is effective for particular target regions such as saddlebags, muffin tops, and double chins that are difficult to remove with regular diet and physical exercise alone. However, it’s not practical for general weight loss. When attempting to lose total body mass, exercising regularly and adhering to a calorie-controlled diet remains the most prudent long-term strategy.\nCryo Slimming will significantly boost males’ and females’ self-esteem by removing stubborn fat and contouring/shaping the body without undergoing surgical distress.\nSome patients achieve satisfactory results after only 3 to 6 cryo slimming sessions, with each session resulting in a loss of up to 1cm. It is recommended to leave a 14-day gap between sessions to allow natural elimination.\nAs with any treatment, a good diet and a balanced lifestyle will assist you to quickly achieve your fitness goal.\nThe Advantages Of Cryo Slimming\nAside from the fact that Cryo Slimming is a non-invasive procedure., it has additional benefits:\nA painless therapy that can last as quick as a half-hour. No downtime is needed. It fits into hectic lifestyles. After just a single treatment, results are quantifiable. More affordable than expensive surgeries. In comparison to surgical procedures, Cryo Slimming is unquestionably a less painful, risk-free, and less terrifying option. Who are the most qualified candidates for Cryo Slimming?\nSuitable candidates for the Cryo Slimming method are anyone who wants to cure tough regions of fatty deposits that are not improving with diet and exercise alone. It’s for people who want to treat them quickly and effectively. We believe that a healthy lifestyle should be followed in conjunction with any of our therapies to gain possible advantages.\nWhat is the sensation like during the treatment?\nThe treatment begins and finishes with a warming sequence that makes use of the Cryostar wand to enhance blood flow, while the cold phase feels similar to a deep tissue ice therapy. Customers often describe their service as comfortable, if not downright pleasant in many situations.\nHow could you have the best possible results?\nCryoSlimming is not a substitute for a healthy diet and regular exercise; instead, it is considered the hidden weapon in any transformation program. It is recommended that you increase your water consumption during any CryoSlimming session to obtain the most significant potential outcomes. It is also recommended that patients undergoing CryoSlimming avoid processed sugars to the greatest extent feasible.\nThe following pre and post-treatment recommendations will assist you in achieving the most remarkable potential outcomes from your CryoSlimming sessions: Avoid all forms of refined carbs 2-3 hours before and immediately following a CryoSlimming procedure. Avoid any sweets for 4-5 hours pre and post-workout, if feasible. This is applicable for all carbohydrate-containing foods, such as pasta, rice, pastry, cereal, and fruits. This is because cold inhibits and backtracks the adipocyte. Eating sugar may provide sustained energy to these cells, therefore interfering with or reducing the efficiency of the cell-death process. A lymphatic cycle takes 15 minutes to complete. Help your system perform optimally throughout this time by consuming lots of water. Other activities that assist the lymphatic system, such as lymphatic massaging or an infrared sauna, may be beneficial. Avoid exercising just before a session. It will be more difficult to adequately chill the body if you have just completed a strenuous workout. When compared to other fat freezing techniques, how does CryoSlimming differ?\nCryoSlimming is an entirely non-invasive and natural method of weight loss. Instead of suction, which may be harmful to the skin’s flexibility, the changes in temperature during a CryoSlimming procedure actually have an additional toning benefit, which aids the production of collagen and elastin.\nComplete Three-Phase Treatment with Cryo Slimming\nBy integrating three distinct scientifically proven fat-burning technologies, CRryo Slimming offers clients exceptional value.\nPhase 1: Lipolaser – breaks the walls of fat cells, allowing them to destabilize and release their content, making it more susceptible to removal during phase 2. Phase 2: Cryolipolysis — a non-invasive, safe option to conventional lipo in which fat cells are targeted and cooled to induce their natural demise. In weeks, the body naturally metabolizes the deceased fat cells. The leftover cells condense, resulting in a decreased thickness of fat layers. During this phase, vitamins and minerals are applied to the skin to increase the effects. Phase 3: Cavitation — ultrasonic cavitation disturbs the fatty tissue tissues, triggering the additional breakdown of the targeted tissue and allowing for enhanced fat-cell metabolism.\nFollowing the treatment, the candidate’s treated region will be red; this is typical since the skin was recently in touch with a freezing application. This redness generally subsides after a few hours of therapy and the next day in the worst-case situation. While your urine may seem somewhat darker as your lymphatic system flushes out toxins, it is critical for candidates to drink at least 2 liters of water each day, not only for general health but also to enhance drainage and keep hydrated.\nIf you have any of the listed contraindications, cryo slimming is not a good option for you: Raynaud’s syndrome with severe manifestation Individuals who have extremely weak circulation Women who are pregnant Breastfeeding a baby Diabetes mellitus Cancer Cirrhosis of the liver Kidney Disease Progressive Diseases\nIf you want to know more about the treatment, book an appointment with clinics like Ardor Laser Skincare and discuss your goals with a professional. Enjoy the benefits of Cryo Slimming and be amazed bi its amazing sensation when the procedure will be done.", "pred_label": "__label__POS", "pred_score_pos": 0.552590012550354} +{"content": "Product\nLapolla™ Insulation is an advanced home insulation solution, designed to meet the needs of modern households. It has been manufactured to meet the deficits presented by fibreglass insulation. This spray foam offers impressive thermal qualities by preventing warm air from leaving your home. It effectively reduces air leakage while ensuring you save up to 45% on energy bills every year. This is done by creating an impenetrable air barrier, locking in warm air and keeping cold air at bay. This improves your property’s EPC rating, reduces the risk of moisture damage and offers a lifetime of performance.\nUnlike traditional fibreglass insulation, SPRAY FOAM expands up to 100x upon contact with the chosen area of application. It easily fills gaps and awkward corners, ensuring a full and complete insulation throughout. Installed by FoamTEK it adapts to suit any structural design and helps deter pests too. Our modern insulation solution can be used in attic spaces, within internal stud walls, and underneath the flooring. Offering superior energy efficiency, it not only saves you money but also produces an instant return on investment. As a non-harmful chemical option, it has been blown 50% with water to create an industrial-level foam. The chance of detecting airborne pollutants such as dust, dirt and carbon monoxide significantly minimises, improving the quality of your household air. For these reasons and more, FoamTEK is swiftly becoming the spray foam installers of choice.\nFor more information about FoamTEK Insulation and how WE can improve the thermal efficiency of your property, get in contact today.", "pred_label": "__label__POS", "pred_score_pos": 0.6168766021728516} +{"content": "Vaccines formulated from adenoviral vectors, or mRNAs encoding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, protect against coronavirus disease 2019 (COVID-19) and permit an effective strategy for combating the COVID-19 pandemic. Vaccines such as these possess the ability to induce the production of neutralizing antibodies within vaccinated individuals. The S protein plays a key role in viral entry into host cells, which is inhibited by these neutralizing antibodies.\nStudy: B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination. Image Credit: Immersion Imagery/ Shutterstock\nThe vaccines currently used present the S proteins of viruses that were in circulation early during the pandemic as antigens to the immune system. However, variants of concern (VOCs) have emerged within later stages of the pandemic with mutated S proteins that allow for augmented transmissibility and/or immune evasion.\nBetween April and May 2021, a large surge of COVID-19 cases was identified in India, caused by a new variant (B.1.617). This new variant then branched off into B.1.617.1 (Kappa variant), B.1.617.2 (Delta variant), and B.1.617.3 variants. In a study published in\nCell Reports, researchers addressed the question of using reporter particles pseudotyped with the S protein of SARS-CoV-2, which are suitable tools to examine SARS-CoV-2 neutralization antibodies. The study\nFirstly, the authors examined whether the Delta variant S protein mediates entry into cell lines used frequently in research into SARS-CoV-2, including Vero, 293T, Caco-2, and Calu-3 cells, all of which express endogenous angiotensin-converting enzyme 2 (ACE2). The authors observed that the Dela S protein did mediate cell entry into Vero cells and 293T cells with the same efficacy as the original wild-type strain.\nThe S protein can also drive the fusion of neighbouring cells, which results in multinucleated giant cells (syncytia). This has been seen\nin vitro, following directed S protein expression or in infected individuals and post-mortem tissues retrieved from patients who died from COVID-19 related complications.\nDue to SARS-CoV-2 protein-driven syncytium being linked to COVID-19 pathogenesis, the authors examined the Delta variant S protein’s ability to drive cell-to-cell fusion. Interestingly, the authors found that the Delta variant caused larger and more numerous syncytia compared to the wild-type virus.\nThe authors determined whether recombinant antibodies could inhibit delta variant cell entry. The Delta S protein was observed to be inhibited by three out of four antibodies tested. The only antibody that the Delta variant was not susceptible to was bamlanivimab, which suggests that this antibody is not suitable for treating Delta variant associated SARS-CoV-2 infections.\nFinally, the authors tested whether antibodies generated from vaccines or previous infections could inhibit Delta variant cell entry. Plasma from previously infected individuals appeared to inhibit Delta variant S protein with slightly less efficacy when compared to the wild type S protein. Similar results were observed with vaccinations. However, immune evasion was more prominent when compared to convalescent sera.\nImplications\nThis study demonstrates that the Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation. The findings on the Delta variant’s capability of evading antibody-mediated neutralization agree with previous research, although it is more prominent than recently seen.\nIt is also shown in this study that treating COVID-19 with bamlanivimab alone will not be effective. Still, the data suggest that imdevimab, casirivmab, and etesevimab are effective treatment options, specifically if administered early.\nThe findings that the Delta variant spike protein is capable of more cell-to-cell fusion when compared to the wild type suggests that more tissue damage may be caused. Thus suggesting the Delta variant is more pathogenic than previous variants and that viral spread through syncytium formation may contribute to the efficient inter-and intra-host spread of this variant.\nArora, P. et al. (2021) “B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination”, Cell Reports, p. 109825. doi: 10.1016/j.celrep.2021.109825.\nContent Source: https://www.news-medical.net/news/20211011/Delta-variant-exhibits-immune-evasion-enhanced-cell-entry-and-augmented-syncytium-formation.aspx", "pred_label": "__label__POS", "pred_score_pos": 0.9669308066368103} +{"content": "Self-healing Nanocomposites 1Mahatma Gandhi University, Kottayam, India 2Université Bretagne Sud, Lorient, France 3Sree Narayana College for Women, Kollam, India Self-healing Nanocomposites Description\n‘Self-healing’, a nature-inspired phenomenon, has been integrated into various materials including structural components, coating, and films. Materials scientists have been interested in designing functional materials that could repair damage independently during their service life to reduce the maintenance cost and ensure safety.\nThis bio-inspired phenomenon includes potential smart and intelligent materials like self-repairing paints for automobiles, self-recovering screens for mobile phones, self-repairing coatings for oil and gas pipelines, and many more. Recently, with the aim of developing multifunctional smart materials for electronics, construction, automobile, and biomedical applications, researchers have focused on integrating a self-repairing capability into polymers, ceramics, and concrete.\nThe aim of this Special Issue is to cover emerging areas on self-healing nanocomposites, including strategies adopted to develop self-healing abilities in nanocomposites, self-healing polymer nanocomposites, self-healing coatings and films, multifunctional nanocomposites which integrate self-healing ability along with other smart functionalities, etc. Additionally, review articles on self-healing nanocomposites and coatings are welcome.\nPotential topics include but are not limited to the following:\nSelf-healing polymer nanocomposites Self-healing strategies and techniques Self-healing for anti-corrosive nanocomposite coatings Self-healing films and membranes Self-healing coatings for biomedical implants Self-healing textiles Articles Special Issue - Volume 2021 - Article ID 5558457 - Review Article Shape Memory Corrosion-Resistant Polymeric Materials Special Issue - Volume 2021 - Article ID 5561755 - Research Article Sugarcane Bagasse-Derived Activated Carbon- (AC-) Epoxy Vitrimer Biocomposite: Thermomechanical and Self-Healing Performance Special Issue - Volume 2021 - Article ID 6617138 - Research Article Corrosion Resistance Evaluation of Self-Healing Epoxy Coating Based on Dual-Component Capsules Containing Resin and Curing Agent Special Issue - Volume 2021 - Article ID 6650499 - Research Article", "pred_label": "__label__POS", "pred_score_pos": 0.5870621204376221} +{"content": "While doing a routine cesarean section in a pristine operating room at Danbury Hospital, medical resident Corrie Miller and her teammates glanced at each other, flashing back to last summer in Uganda, where they spent days performing hysterectomies on women suffering severe complications from C-sections.\n“Being in the room with the same team in a completely dichotomous setting was like reverse culture shock,” Miller said. “We silently understood, as we looked at each other, the stark contrast between Uganda and home, that our patient has essentially no risk of morbidity and mortality, while in Uganda her risk would be exponentially higher.”", "pred_label": "__label__POS", "pred_score_pos": 0.8669690489768982} +{"content": "Designing a legal function of the future\nStep 1: Understanding and addressing the demand on the legal function\nThe opportunity\nOur client, the GC and his leadership team of a large energy company based in Japan, approached NRF Transform’s Legal Operations Consulting (LOC) team to plan for an extensive period of global growth over the next decade. Specifically, the client wanted to confirm that they had the right team to support the business through this period.\nAt the time of instruction, the legal team had no existing tech tools, processes or plans to work from. However, they knew they would need these in place over the coming years. They approached NRF with the general concept that they wanted to improve, but had no idea where to start, or how they would go about the process.\nThe solution\nIt was apparent that before the client could start the process of improving or even identifying areas for improvement, they should spend time capturing information on the team’s workload and the way they currently managed incoming work.\nThree possible solutions were proposed to tackle this, each with its own pros and cons: task diaries to be completed by the team over a defined period to identify pain points; time recording to be completed by the team to provide structured data on activity levels; implementation of an intake process and accompanying tech tool to effectively monitor the operations of the team. The client opted for the intake system, given its long-term benefits for their legal operations.\nThe client also requested a change management programme to maintain compliance with the implementation of the intake process and tool, but also to engender engagement and enthusiasm with the change.\nThe project involved several stages:\nStep One: Change management workshops with the leadership and wider team to understand the project positioning and goals, introduce the Legal Ops consultants and establish measurements of success. Step Two: Creation of a taxonomy to describe and categorise incoming work. To achieve this, we created a draft from the client’s documentation and interviewed the team for feedback and refinement. Information was then consolidated into a report for the client’s management team and was also shared with the wider team in an anonymised format to transparency amongst all stakeholders. Step Three: Mapping and improving the existing intake process, which was a collaborative stage between our Legal Operations Consulting and Legal Design teams. Client workshops were conducted to refine the process and a new process map was created, highlighting agreed improvements. Step Four: In parallel with implementing the new intake process, Transform worked with a legal technology vendor to customise and deploy an intake tool. Support was given to the client to ensure the taxonomy built into the tool was both suitable from a legal perspective and feasible from a data perspective. Results and benefits A resourcing strategy, underpinned by effective tools, data and team buy-in, to enable Legal to effectively support the organisation’s strategic objectives and planned growth A clearly planned intake and allocation process with high stakeholder engagement resulting in a successful intake system roll out. Consistent capture of data and access to previously unavailable data to position the Legal department as progressive, whilst also demonstrating its value to the business Client stories\nContacts\nContacts", "pred_label": "__label__POS", "pred_score_pos": 0.8654446005821228} +{"content": "In the case of therapies targeting the AML microenvironment, this may symbolize an important limitation in the translation of animal model results to human patients due to the mismatch between human leukemia cells and the mouse BM niche. Practical assessment of niche contribution to AML and pre-clinical testing of fresh niche-targeted therapies require the establishment of disease-relevant magic size systems. in mice that can be used to unravel the part of human being AML microenvironment and to carry out preclinical studies for the development of fresh targeted treatments. (Shwachman-Bodian-Diamond syndrome) gene mutated in Schwachman-Diamond syndrome, a human being congenital BM failure with known leukemia predisposition [174]. Subsequently, it has been reported that mutations activating -catenin in OBs in mice induce myelodysplasia, rapidly progressing to AML [175]. These investigators also found that triggered -catenin signaling is present in OBs of one-third of MDS and AML individuals and it is the most active pathway in stromal cells of MDS individuals, suggesting that it may sustain dysplastic hematopoiesis and progression to MDS and AML also in humans. Therefore, focusing on this pathway may represent a new restorative approach for this subgroup of individuals. Treatment of leukemic mice expressing constitutively active -catenin in their OBs with all-trans-retinoic acid (ATRA) inhibited -catenin signaling, improved anemia and thrombocytopenia, decreased the amount of blasts in BM and blood, and prolonged overall survival [176]. Moreover, it has been demonstrated that triggered -catenin leads to the development of AML through upregulation of Jagged1 manifestation in OBs and subsequent activation of Notch signaling Mouse monoclonal to CD4 in hematopoietic cells [175]. Inhibition of osteoblastic Notch signaling by Jagged1 deletion or pharmacologic treatment with -secretase inhibitors prevents AML development in mice. Furthermore, blocking Jagged1/Notch signaling between OBs and HSCs using an anti-JAG1 antibody efficiently treated OB-induced MDS/AML in mice [177]. The Koustenis group attributed this niche-induced leukemogenesis to the oncogenic part of FoxO1 in OBs that interacts with -catenin and upregulates Notch ligand manifestation [178]. This observation suggests focusing on FoxO signaling in OBs may be helpful for individuals with constitutive activating -catenin mutation. Finally, activating mutations of the Tyrosine phosphatase SHP-2 (encoded by Ptpn11 gene) in MSCs and osteoprogenitors, already found in Noonan syndrome and associated with an increased risk progression to leukemia, induce juvenile myelomonocytic leukemia-like myeloproliferative neoplasm in mice through the overproduction of chemokine CCL3 [179]. This study defines CCL3 like a potential restorative target for leukemia progression control Raphin1 in individuals with Noonan syndrome. While these findings in mice present direct evidence for OB-induced leukemogenesis and although some observations in mouse models have been linked to human diseases, it remains unclear whether alterations to the microenvironment can travel leukemia in humans. Emerging reports of donor cell leukemia in individuals receiving Raphin1 allogeneic transplantation (only 1C5% of all post-transplant leukemia relapses) seem to suggest an oncogenic part of the microenvironment that can lead to secondary malignancy also in humans [180]. 3.3. Adipocytes-Rich Market and Fatty Acid Metabolism Adipocytes derive from MSC differentiation are common in the BM stroma and their quantity augment with age. MSCs from AML individuals have a higher propensity to differentiate into adipocytes, and the relationships between adipocytes and AML blasts in the BM market support their survival and proliferation [181]. We recently shown using an innovative in vivo model of humanized hematopoietic market that AML-MSCs-derived ossicles contained a significantly improved portion occupied by adipocytes [154]. AML blasts modulate adipocyte rate of metabolism, inducing lipolysis of triglyceride to fatty acid (FA) through induction of hormone-sensitive lipase and growth differentiation element 15 (GDF15) launch [182,183]. In these conditions, AML Raphin1 blasts shift their rate of metabolism toward fatty acid -oxidation (FAO), obtaining the energy required for leukemic growth and proliferation. These AML-adipocyte relationships have been linked to chemotherapeutic resistance [184,185]. Obesity is associated with poor clinical end result in leukemic individuals and.", "pred_label": "__label__POS", "pred_score_pos": 0.7023677825927734} +{"content": "Monday, September 27, 2021\nThis article examines the economic consequences of collusion in both the output market and one of the input markets. We examine the results of sequential collusion, which leads to complications and inconsistencies in measuring antitrust damages. We also examine simultaneous collusion in both the input and output markets. Ultimately, the profit maximizing equilibrium are identical but there are complications along the way to the final collusive equilibrium. The article explores the private plaintiff problems involving antitrust standing, proving antitrust injury, and estimating antitrust damages.\nhttps://lawprofessors.typepad.com/antitrustprof_blog/2021/09/monopoly-and-monopsony-antitrust-standing-injury-and-damages.html", "pred_label": "__label__POS", "pred_score_pos": 0.8651899099349976} +{"content": "Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while their organs were forming during the embryonic stage of their development. In a study published in PLOS ONE, researchers affiliated with the University of Campinas...medicalxpress.com\nFonte:https://www.newsbreak.com/news/2226482172169/study-shows-how-low-protein-intake-during-pregnancy-can-cause-renal-problems-in-offspring", "pred_label": "__label__POS", "pred_score_pos": 0.9831534028053284} +{"content": "It has long been understood that an athlete’s performance depends not just on their physical prowess and fitness but also on psychological factors which help them to compete to the best of their ability. Even harking back as far as the ancient Olympics which began in Ancient Greece in 776BC, scholars have been fascinated by […]", "pred_label": "__label__POS", "pred_score_pos": 0.7268714904785156} +{"content": "Boundary confusion refers to an assumption of intimacy that is not agreed upon by both parties, which leads to a sense of violation or crossing the line. It reflects a failure to recognize the physical or psychological boundary and distinctiveness of the other by either presumption of connection or lack of awareness of another’s personal space. It can be confusing for someone who feels they made a mistake but doesn’t understand why or how, and it can be alarming for those whose signals are being misread.\nAfter growing up in a household with extremely loose emotional boundaries, I soon learned the importance of establishing my own personal boundaries as quickly and clearly as possible. And, in recent years, I have even managed to become more eloquent about when and how to set them.", "pred_label": "__label__POS", "pred_score_pos": 0.5487554669380188} +{"content": "\"Directors must consider whether the company will still be solvent following a proposed distribution. Directors may be personally liable should the company become insolvent.\"\nLack of government support\nThe warning will come as an additional blow to company directors, many of whom have not been eligible for any Covid-support schemes.\nAs reported by\nFTAdviser, the Budget on March 3 discussed continued support for those eligible for the CJRS - furlough scheme - and the self-employment income support scheme.\nHowever, Chancellor Rishi Sunak's statement continued to exclude support for over 700,000 limited company director/ shareholder businesses.\nSuch directors typically receive most of their remuneration through dividends, an acceptable practice under existing tax rules, and as such continue to receive no support under either the CJRS or the SEISS rules.\nsimoney.kyriakou@ft.com", "pred_label": "__label__POS", "pred_score_pos": 0.9392101764678955} +{"content": "If you’re interested in learning how Yonomi can help simplify your smart home initiative, please contact our sales team. Is the Smart Home Still an Open Field of Opportunity?\nToday’s digital consumer has graduated beyond exploring the latest iPhone specifications, browsing through streaming apps on their TVs and discovering new ways to avoid internet ads. Consumers are more informed today than they ever have been, with Gen Z leading the pack as the most research- and value-driven generation yet. They also have the highest expectations for customer experience and ease-of-use. To outperform the competition, modern-day service providers are adopting strategies that rise above the noise, building personalized relationships and addressing real customer needs.\nFrom products to platforms, the smart home is consistently described as a fragmented market with numerous challenges. Providers are struggling to build an end-to-end holistic experience from these isolated platforms. However—with investment—evolving and educating both service providers and consumers offers a win-win solution.\nConsumer spending on smart home products is expected to reach well over $157 billion by 2023. While new smart home adopters are addressing one-off use cases like security or home entertainment, high-fiber users often have more than 16 connected devices in the home spanning multiple use cases like energy management, home maintenance, security and more. It’s quite simple: smart home products simplify the home, but the customer chooses how much simplification they want and where. With a trusted broadband provider guiding their path and unifying the experience, pioneering the future of the home can be safe, easy and fun.", "pred_label": "__label__POS", "pred_score_pos": 0.6246558427810669} +{"content": "How can socio-economic transitions be better managed? Lessons from four historical cases of industrial transition\nThis report uses four case studies from across the globe to draw lessons on how cities and regions can equitably manage the decline of major industrial and mining activities and minimize disruption to local economies. It finds commonalities among decarbonization transitions in Australia, the United States, the United Kingdom and South Africa, expanding the scope of success from simply closing industries to including social and economic equity in the transition process.", "pred_label": "__label__POS", "pred_score_pos": 0.9769659638404846} +{"content": "This morning I heard that a gentle soul I used to work with took his own life. I have no insight into the circumstances, but I remember him as dedicated, loyal, incredibly intelligent, and unappreciated.\nWork is so powerfully entwined with our identity, and sense of worth, but we have made it into a sharp mechanical thing, measured by money. We demand that people leave their emotions at home, and yet we expect passion, creativity, and ownership.\nIt is 2019 and the world is a rapidly evolving place, connected, concerned, and complicated - we need our people to bring their whole selves to work, and we need to invest in their commitment if we want our businesses to survive.\nThe real world runs on compassion.", "pred_label": "__label__POS", "pred_score_pos": 0.9897039532661438} +{"content": "What You Need To Know About Kamado Grills What is a kamado grill?\nA coal kamado is a customary Japanese ceramic cooking appliance. Today’s most typical model is a foldable ceramic pot with grills and ventilation control openings. They are usually referred to as earthenware grills. Despite their modest design, the quality of the food produced by these grills has resulted in a cult following. Ceramic grills are also far more weatherproof than iron grills, which tarnish in many areas.\nWhy use a kamado grill instead of a metal grill?\nWith reduced circulation, the humidity in foods is better retained due to improved temperature management and uniformity. Because coal flames are at the maximum volume for the available circulation, adjusting airflow is how you control heat. Because a slow cooking chef can operate for up to 20 hours, the volume of air movement and absorption it generates has a significant impact on the moisture content of the final piece. A ceramic grill’s larger walls produce thermal mass, which gives it stability and reduces heat loss. On the other hand, iron grills radiate heat and need more fuel and ventilation to keep the boiling temperature stable. When using a metal grill, you should modify the flow to compensate for fluctuations in room temperature.\nStability\nThe persistence created by the heat trapped in the walls of the ceramic grill reduces temperature changes. Extended, short, and unhurried cooks become much more user-friendly as an outcome of this calmness. To keep your goal cooking temperature on a metal grill, you must alter the airflow to compensate when temperatures decrease, or the wind begins to flow.\nBody- Glazed Pot Ceramic Grills\nThey have a spherical form and are constructed with straps around the center of both the top and bottom, connected by a hinge. The issue with this concept is that you can’t evade physics; the grills stretch and shrink when warmed, and the belts need to be adjusted all the time. They leak and catch fire gaskets when they lose this setting.\nSome qualities are included in these and are regarded as an element of what has increased the same appeal. For openers, they are well-known for providing even temperature. It is worth noting that with these, you can use new textures for frying, and as a consequence, by picking the right, heat is spread uniformly throughout the domed framework, resulting in evenly cooked food. Second, they are well-known for their adaptability. This is connected to using various cooking sources, including charcoal, wood, and gas. Furthermore, it is vital to note that any wood can be used with these, which adds to their appeal. Additionally, if you’re using a gas cooker and want to add some wood aroma, these two can be utilized simultaneously.\nHeating can be regulated to be either high or low in this respect. When using the same, you must select a design that accurately meets your culinary requirements to guarantee that you are secure and consider it practical. At this stage, it is critical to emphasize that temperatures must always be maintained because too high temperatures can cause the ceramic to shatter.\nConclusion\nLastly, it’s worth noting that these can be divided into two categories. There are pre-made versions and customizable ones that allow the customer to choose the characteristics they require. Hence, they will be capable of obtaining patterns that complement their existing décor. The preliminary test with a\nKamado grill is learning how to utilize it. In most cases, a user manual will be provided. At the same time, this is true as soon as a user has control over the heat, which is done by the air circulation.", "pred_label": "__label__POS", "pred_score_pos": 0.6306866407394409} +{"content": "Directorate for Employment, Labour and Social Affairs\nImproving the Provision of Active Labour Market Policies in Estonia\nThis report on Estonia is the seventh country study published in a series of reportslooking into how policies connect people with jobs. It discusses the set-up and performanceof active labour market policies (ALMPs) in Estonia. In particular, the report analysesthe institutional and regulatory framework of ALMP provision in Estonia, assessesthe need for ALMPs in the Estonian population and evaluates whether ALMPs reach thepeople they are targeted to. For that purpose, the report relies on the analysis ofa rich set of linked administrative data which allow to identify the labour marketobstacles faced by people furthest from the labour market, and identify gaps and overlapsin the ALMPs and related support provided to them.", "pred_label": "__label__POS", "pred_score_pos": 0.8606004118919373} +{"content": "Definitions of contacts. Household-based contacts include the index case’s immediate and extended households defined by dwelling. History-based contact tracing relies on active contact tracing for the preceding 2 days, including household (close) contacts and community (casual) contacts. The immediate household consists of the index case’s place of residence at the time of diagnosis. The extended household comprises the index case’s immediate household in addition to their other dwellings (i.e., core, regular and on/off)", "pred_label": "__label__POS", "pred_score_pos": 0.9536064863204956} +{"content": "Workers' Comp Are Demands for Spend Accountability Becoming More Complex? Look to EHO’s PBM360™ platform for integrated claims processing and real-time, detailed data reporting\nEHO is dedicated to getting injured employees back to work with positive outcomes while controlling utilization and prescription drug cost. By understanding the client’s plan requirements, EHO is able to recommend immediate cost-saving adjustments during the benefit design setup process. Complete customization is offered at no additional charge. Using EHO’s proprietary, cloud-based PBM360\nTM claims processing platform, clients can view real-time metrics on a plan level or individual member basis. Alerts and notifications can be tailored to plan guidelines to control dosing, spending limits, step edits, and prior authorizations.\nEHO is sensitive to the opioid crisis. Research on medical outcomes when opioids are used in workers’ compensation demonstrates that opioid use beyond the acute phase can impair function and be a barrier to recovery* EHO has partnered with Sure Med Compliance, the industry leader in opioid prescribing compliance, offering in-network providers a tool that helps ensure only patients that truly need opioids receive them and only for as long as needed.\nEHO Caters to Workers’ Compensation Plans State reporting Injury-specific formularies Detailed reports to account for spend Cost management strategies ePrescribing 24/7 live call center Real-time prior authorizations A Commitment to Clinical Services\nEHO effectively manages clinical utilization through a “real-time audit” of high-cost claims. All claims requiring a prior authorization are reviewed by clinical pharmacists with years of experience in the industry. Pharmacists review prescriptions before they are filled utilizing a live connection into the PBM360 claims processing system. The program has reduced clients’ annual pharmacy spend by between 15% to 20% through direct cost savings on existing medications and cost avoidance on newly prescribed medications.", "pred_label": "__label__POS", "pred_score_pos": 0.749774694442749} +{"content": "Burnout is a state of physical, mental, and emotional exhaustion that emerges from a prolonged period of stress or external demands. When we fail to listen to or are unable to respond to the limits of our internal warnings that we are doing too much, we reach “burnout.” While general symptoms of exhaustion are usually present, the most notable symptom of feeling burnt out is a loss of motivation, especially to complete work or maintain a relationship that was previously important or meaningful to us. This usually stems from feeling that our previous intense efforts have not accomplished the desired results or are now pointless. Fortunately, burnout is not a permanent state, but it takes some care and intention to replenish our spirits and revive.", "pred_label": "__label__POS", "pred_score_pos": 0.9545989632606506} +{"content": "A low carbon and circular industry for Europe\nThis paper looks at the opportunity for the circular economy to reduce the EU's greenhouse gas...\nInitiated by the Danish government, the programme aims to shift public procurement to support the transition to a circular economy. Through the partnership, members work to integrate procurement policies that emphasise circular economy criteria such as the use of non-toxic chemicals, extended product lifespan, and the cycling of biological and technical materials.\nPublic procurement refers to the process by which public authorities purchase goods and services from companies. The impact of public procurement on the transition to a circular economy could be significant as it is worth around EUR 2 trillion in the European Union, around 19% of GDP. Integration of holistic procurement requirements can increase demand for circular products and services, drive innovation, minimise environmental degradation and save public money, as the costs of the product’s entire life cycle will be considered.\nIn Denmark, where the public sector procures goods and services for around EUR 38 billion annually, a national initiative is aiming to shift the country’s public procurement practices to support a green transition of the market.\nThe Partnership for GPP is a collaborative initiative between Danish regions, municipalities and the Ministry of Environment and Food on common objectives for green procurement. The current 14 partners have committed themselves to integrate green goals in their procurement policies as well as greening their procurement on 11 specific product groups. Criteria include recyclability, number of chemicals, product lifespan and total cost of ownership – all elements essential for the transition to a circular economy. The partnership’s total volume of procurement is significant at EUR 5 billion.\nThe Partnership for GPP was established in 2006 by the then Minister of Environment, Connie Hedegaard, and Denmark’s three largest municipalities. The objective is to create a coalition of governmental bodies to increase procurement volumes and therefore have a larger impact on the market. The partnership is in close collaboration with the Forum for Sustainable Procurement, which is a broader national initiative targeting all stakeholders with an interest in procurement, and has been running since 2011.\nThe key activities of the Partnership for GPP revolve around collaboration, capacity building and sharing of knowledge and experiences. Through the partnership the members get access to knowledge on how to integrate environmental and economic requirements into tenders, and a common set of criteria they can use to strategically drive the market in the same direction. Membership is free, but active participation and the development of specific actions are requirements.\nOdense Municipality was to construct 40 new residences for youths with disabilities. By rethinking the tender and implementing green procurement requirements the new buildings were constructed using fewer unwanted chemicals, alternative materials such as paper wool for insulation, recycled bricks, and energy efficient solutions including LED lighting and solar water heating. The construction cost of the residences was 5% higher than business-as-usual, but it is expected that the extra investment will be repaid quickly due to lower operating costs (source: gronneindkob.dk, ansvarligeindkob.dk).\nThis paper looks at the opportunity for the circular economy to reduce the EU's greenhouse gas...\nBlackRock launched a circular economy public equity fund.\nPhilips is a global health technology company focused on improving health and enabling better...\nOur thought-leading insights into the opportunity of a circular economy. Download all of our...\nThe Ellen MacArthur Foundation works in Education & Training, Business & Government, Insight & Analysis, Systemic Initiatives and Communications to accelerate the transition to a circular economy.\nCharity Registration No.: 1130306\nOSCR Registration No.: SC043120\nCompany No.: 6897785\nEllen MacArthur Foundation ANBI RSIN nummer: 8257 45 925", "pred_label": "__label__POS", "pred_score_pos": 0.5923221111297607} +{"content": "What cialis is and what it is used for?\ncialis is a treatment for adult men with erectile dysfunction. This is when a man cannot get, or keep a hard, erect penis suitable for sexual activity. Cialis has been shown to significantly improve the ability of obtaining a hard erect penis suitable for sexual activity.\nCialis contains the active substance tadalafil which belongs to a group of medicines called phosphodiesterase type 5 inhibitors. Following sexual stimulation cialis works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis. The result of this is improved erectile function. Cialis will not help you if you do not have erectile dysfunction.\nCialis(Tadalafil 20mg)\nIt is important to note that cialis does not work if there is no sexual stimulation. You and your partner will need to engage in foreplay, just as you would if you were not taking a medicine for erectile dysfunction.\nCialis (tadalafil) is typically taken as a 10 mg dose about 30 minutes before sexual activity when needed. The dose can be adjusted anywhere from 5 mg to 20 mg depending on response Cialis (tadalafil) should not be taken more than once a day at any dose.", "pred_label": "__label__POS", "pred_score_pos": 0.7058377861976624} +{"content": "As part of the EU’s 2020 Industrial Strategy, the European Commission is planning the green and digital transition of 14 key industrial ecosystems for Europe. The European Council of Shopping Places was contacted to provide input on what it views as potential barriers in this transition for the retail sector, along with recommendations on how to address them. ECSP’s response is available here.", "pred_label": "__label__POS", "pred_score_pos": 0.7488558292388916} +{"content": "We explore the utility of an on-demand multimodal conversational platform in extracting speech and facial metrics in children with Autism Spectrum Disorder (ASD). We investigate the extent to which these metrics correlate with objective clinical measures, particularly as they pertain to the interplay be-tween the affective, phonatory and motoric subsystems. 22 participants diagnosed with ASD engaged with a virtual agent in conversational affect production tasks designed to elicit facial and vocal affect. We found significant correlations between vocal pitch and loudness extracted by our platform during these tasks and accuracy in recognition of facial and vocal affect, as-sessed via the Diagnostic Analysis of Nonverbal Accuracy-2 (DANVA-2) neuropsychological task. We also found significant correlations between jaw kinematic metrics extracted using our platform and motor speed of the dominant hand assessed via a standardised neuropsychological finger tapping task. These findings offer preliminary evidence for the usefulness of these audiovisual analytic metrics and could help us better model the interplay between different physiological subsystems in individuals with ASD.", "pred_label": "__label__POS", "pred_score_pos": 0.9998743534088135} +{"content": "However, at least quickly absorbs insulin the sugar, and for active mental activity is a sharp decline, and relief. So, as you can see, the sugar in its pure form - double-edged sword. The good news is that the glucose contained in some carbohydrates, the use of which does not cause such a sharp downturn. After eating breakfast on the right product, there is no doubt that his action will last a couple of minutes, much longer. These products are starchy carbohydrates: bread, rice and other cereal products, nuts, beans, and potatoes. Regularly eating these foods for breakfast, school children and students receive an excellent foundation for employment, supporting your brain for the entire school day. In summary, we can say that the best food for a snack during intense mental activity will not be traditional chocolate or sweet fizzy drinks, and bread with nuts. Fat: interfere with the brain as it turned out, in excess fat is not only spoil the figure, but also significantly impair brain function.", "pred_label": "__label__POS", "pred_score_pos": 0.873153030872345} +{"content": "Prohibition, Privilege and the Drug Apartheid: The failure of drug policy reform to address the underlying fallacies of drug prohibition.\nAlternative models of legalisation, decriminalisation and regulation are emerging across the world. Whilst critics have asserted that prohibition and the ensuing ‘war on drugs’ lack both an evidence base and legitimacy, reformers are embracing these alternatives as indicators of progressive change. This paper, however, argues that such reforms adhere to the same arbitrary notions, moral dogma and fallacious evidence base as their predecessor.", "pred_label": "__label__POS", "pred_score_pos": 0.5185725688934326} +{"content": "The\ncapacity to aculate and recognize the profitability of deal-of-the-day promotions (DoDs) is of important significance for traders. It is likewise difficult as it calls for those traders to keep in mind lengthy-term, cross-selling, and cannibalization results and choose the correct bargain for the promotion. The authors broaden and enforce a version as a unfastened on-line calculator to assist traders to decide the income they could generate from those promotions. This calculator evaluated nearly 3, seven-hundred DoDs from the traders’ and providers’ perspectives. To advantage perception at the anticipated profitability of DoDs, the authors analyzed 627 of those deliberate promotions and 30 found out promotions. The outcomes imply that two-thirds of the deliberate and all found out DoDs are anticipated to be worthwhile withinside the lengthy term. Yet, DoDs are not likely to repay withinside the brief term. The findings additionally display that unredeemed coupons strongly growth income, specifically the ones of the provider.", "pred_label": "__label__POS", "pred_score_pos": 0.920271098613739} +{"content": "A tremendous amount of money is being steered toward personalized learning (PL) initiatives at the federal, state, and local levels, and it is important to understand the return on the investment in students’ futures. It is only through rigorous discussions that educators and policymakers will be able to determine if PL is a passing fad or if it possesses the staying power necessary to show a positive impact on student achievement.\nEvaluation of Principles and Best Practices in Personalized Learning is a critical scholarly publication that explores the modern push for schools to implement PL environments and the continuing research to understand the best strategies and implementation methods for personalizing education. It seeks to begin creating a standardized language and standardized approach to the PL initiative and to investigate the implications it has on the educational system. Additionally, this book adds to the professional discussion of PL by looking at both the advantages and disadvantages of PL, the teacher’s role in PL, creating a PL program to scale, the role of technology and PL, the special education population and PL, emerging research on PL, and case studies involving PL. Featuring research on a wide range of topics such as blended learning, preservice teachers, and special education, this book is ideal for teachers, administrators, academicians, policymakers, researchers, and students.", "pred_label": "__label__POS", "pred_score_pos": 0.6664151549339294} +{"content": "Every year roughly 300 million fish are released from B.C. hatcheries to enhance dwindling stocks and sustain fisheries. Despite overwhelming investments of time and money, little has been done to fully review the effectiveness of salmonid enhancement and impact on wild populations in BC. The Hatchery Effectiveness Review is aimed at optimizing hatchery practices, improving the efficiency of enhancement strategies and ultimately contributing to a more sustainable future for wild salmon. Hatchery vs Wild Salmon Survival\nResults to date from our Marine Science Program highlighted the poor survival of hatchery fish from Cowichan River Hatchery, which consistently survive at less than half the survival rates of wild fish from the same system. While hatcheries and enhancement techniques will likely continue to be a necessity for the sustainability of wild Pacific salmon, there is room for improvement. This is particularly important given the ongoing fisheries restrictions necessitated by the very poor status of some Chinook and Coho salmon stocks, as well as the push for more production of Chinook salmon to meet prey needs for endangered Southern Resident Killer Whales.\nThe primary components of the program include:", "pred_label": "__label__POS", "pred_score_pos": 0.6024023294448853} +{"content": "We use our capital to create economic, social, and environmental impact, by backing companies that are addressing the UN Sustainable Development Goals, which are aimed at providing climate solutions, preserving oceans and forests, providing better education, ensuring well-being and health, and ending inequality and poverty.\nWe invest not only our capital but are also interested in being part of the journey of the founders we back, by supporting their dreams and enabling the achievement of their vision.\nWe also believe in backing womxn-led businesses and under-represented founders, as these businesses are strongly under-funded, and we believe in their ability to perform better over time – generating more revenue, being more capital efficient and getting to profitability more quickly.", "pred_label": "__label__POS", "pred_score_pos": 0.997220516204834} +{"content": "Affairs & Infidelity Recovery\nThe discovery of an affair is a devastating and heartbreaking experience in a relationship. Infidelity causes a deep betrayal tearing the foundation of trust in the relationship and marriage. It is often shocking to the betrayed partner and can leave the individual feeling alone, blindsided, confused, and devastated.\nWhile the discovery of an affair is damaging and traumatizing, there is the hope of recovery. A couple does not necessarily have to resort to a break-up or divorce. Couples often are challenged with overwhelming feelings of anger, hopelessness, despair, and sadness. If they remain stuck in this place, it may lead to a negative cycle of bitterness and resentment.\nCouples therapy offers hope for an opportunity for healing, forgiveness, and growth leading to positive change if partners are willing to engage in the process. The partner who had an affair must end contact with the affair partner to rebuild and repair trust. We can navigate the road on this journey together to guide you into a meaningful, satisfying and joyful relationship.\nDr. John Gottman and Dr. Julie Gottman, world-renown relationship researchers, provide extensive evidence-based research in betrayal and affair recovery models for couples. Additionally, Esther Perel, a couple and relationship expert in affairs and infidelity, includes information on intimacy and sexuality. After conducting a couples’ assessment, I provide a treatment plan and techniques to meet your goals. Emotionally Focused Therapy offers to understand the couple’s dance of pursuer and withdrawer, processing and uncovering deep feelings, providing insight and stability in the relationship.\nAmbivalence exploration helps individuals unsure of whether to remain in the relationship process their emotions and the benefits and risks of their decision. Couples therapy is helpful to those who want to commit to their relationship goals in reconnecting, repairing, rebuilding trust, healing, setting healthy boundaries, and strengthening their relationship.\nWhat is Considered Infidelity?\nThere is a wide variety of what exactly counts as cheating in a relationship or marriage. One partner may view cybersex and pornography as infidelity, while the other partner may not. Some may view an emotional affair as harmless and may begin to invest their energy and time outside of their relationship. Others may only consider real sex outside of the marriage as a betrayal and may entertain others’ company, and may not view an emotional affair as infidelity.\nWhat Causes Infidelity?\nThe research studies demonstrate that most adults have an expectation of monogamy in a romantic relationship and marriage. However, extramarital affairs are a result of several reasons for straying outside of a committed relationship. A stable relationship requires emotional and physical intimacy and a meaningful, fulfilling, and satisfying relationship. The reasons that an individual may engage in an affair include the following:\nEgo Boost\nLack of emotional intimacy\nAs an ending of relationship or marriage\nLow Self-Confidence\nSex Addiction\nAvoidance of issues\nDepression\nSeveral Types of Infidelity Sexual Affair\nA sexual affair involves a physical intimate sexual liaison, romantic or passionate attachment driven by desire between two individuals and without knowing the partner knowing of the affair. Boundaries in committed relationships dissolve when a partner steps outside of the committed relationship and marriage, establishing mutual agreements, limitations, and physical exclusivity rules. An individual becomes involved in a physical, sexual clandestine affair without emotional attachment outside of the committed relationship and marriage. A lustful passionate sexual affair is generally short-lived, with most lastly an average of six months. Nevertheless, there have been affairs that are secret and hidden and have lasted for years. Overall, most physical, sexual infidelities cannot sustain the level of attraction and excitement without an emotional connection and tend to fade away. The expectation of sexual exclusivity broken by the individual that strays outside of the marriage causes a deep sense of betrayal, loss, devastation, and trauma to their partner.\nObject Affair\nThe individual’s attention is drawn away from the relationship and marriage and replaced by an outside activity, hobby, work, or interest. The individual rearranges their schedules and time making this their priority instead of their partner. “The Golf Widow” is an example where the partner is left alone for long periods while the individual spends their weekends enjoying golfing with their friends while neglecting their primary relationship. Individuals may become obsessed with their professional careers and spend most of their time focused on work while ignoring their partners and family. The excessive amount of energy, investment, time, and resources in pursuing these interests interferes with the relationship and marriage’s emotional and physical intimacy.\nCybersex Affair\nA significant phenomenon on the Internet is online infidelity involving both an emotional and physical affair whereby the individual develops a connection known as cybersex or an online affair. It may begin as cyber flirting and escalate to an individual connecting to another in cyber sexual encounters through viewing pornography, live chat rooms, email, and sexting. The powerful attraction of the Internet and sexuality is powerful as it holds power to the relationship and marriage’s negative impact. These infidelities involve secrecy with the potential to take it to the next level and decide to meet in person bringing it from online internet infidelity to a physical affair. Cybersex can become an online sexual addiction with the individual spending more time on the computer than with their partner, destroying the relationship’s intimacy and trust. Often, cybersex is a symptom of problems, sexually compulsive behavior, and a lack of satisfaction.\nEmotional Affair\nOften this starts when the partner becomes emotionally attached and close to another individual other than their partner. It may begin as a friendship and evolve into a severe threat to the relationship. They become involved with an individual of the gender they are attracted to, harming the relationship. The individual may spend a significant amount of time flirting, connecting on the phone, social media, keeping the relationship a secret, and taking away time from their partner. The individual may share sensitive personal information regarding the couple’s love relationship and unfavorable comparisons between their partners and friends. An emotional betrayal is as challenging and devastating to heal from as a physical, sexual affair.\nImpact of Infidelity on Partner\nAn affair’s betrayal contains adverse emotional, physical, and psychological effects affecting both partners in the relationship or marriage.\nSymptoms\nShame\nAnger\nDistress\nAnxiety & Panic Attacks\nSleep Disturbance\nSelf-Blame\nOvereating/Undereating\nOver Exercising\nLower work performance\nHigh-risk behaviors\nPost-Traumatic-Stress Syndrome (PTSD)\nIncreased Alcohol and Substance Use\nLow Self-Confidence & Self-Worth\nDepression and Sadness\nIf you have experienced infidelity, it is essential that you heal, process, and grieve the loss as a betrayed partner. Couples therapy can help heal, recover, and grow in rebuilding the foundation of trust in your relationship or marriage. I offer an inclusive, safe, non-judgmental, and non-shaming environment to explore these feelings. I am here to provide compassion, empathy, and support to help guide you in the healing process to recover from the trauma of betrayal.\nReferences\nGottman, J. M. (1994). What predicts divorce? The relationship between Marital processes and marital outcomes. Lawrence Erlbaum Associates, Inc.\nGottman, J. M., & Silver, N. (2012). What makes love last: How to build trust and avoid betrayal. New York: Simon and Schuster.\nGottman, J. M. (2011). The science of trust: Emotional attunement for couples. New York: W.W. Norton and Company.\nGottman, J. M., & Gottman, J. S. (2008). Gottman method couple therapy. A. S.\nGurman (Ed.), Clinical handbook of couple therapy (pp. 138-164). New York, NY, US: Guilford Press.\nGottman, J. M., Gottman, J. S., & DeClaire, J. (2006). 10 lessons to transform your marriage. New York: Crown Publishers.\nGottman, J. S. (2004). Introduction: An abbreviated history and overview of Gottman method couples’ therapy. In J. S. Gottman (Ed.), The marriage clinic casebook (pp. 1-10). New York: W.W. Norton.\nGottman, J. M., & Levenson, R. (2002). A two-factor model for predicting when a couple will divorce: Exploratory analyses using 14-year longitudinal data. Family Process, 41(1), 83-96. Connections with family, friends, and lovers. New York: Crown Publishers.\nGottman, J. M., & Silver, N. (1999). The seven principles for making marriage work. New York: Crown Publishers.\nPerel, E. (2006). Mating in captivity: Reconciling the erotic + the domestic. New York: HarperCollins.\nPerel, E. (2017). The state of affairs: Rethinking infidelity.", "pred_label": "__label__POS", "pred_score_pos": 0.5210757255554199} +{"content": "A new introductory quantum mechanics curriculum\njournal contributionposted on 05.10.2018, 08:22 by Antje Kohnle, Inna Bozhinova, Dan Browne, Mark EverittMark Everitt, Aleksejs Fomins, Pieter Kok, Gytis Kulaitis, Martynas Prokopas, Derek Raine, Elizabeth Swinbank\nThe Institute of Physics New Quantum Curriculum consists of freely available online learning and teaching materials (quantumphysics.iop.org) for a first course in university quantum mechanics starting from two-level systems. This approach immediately immerses students in inherently quantum-mechanical aspects by focusing on experiments that have no classical explanation. It allows from the start a discussion of the interpretive aspects of quantum mechanics and quantum information theory. This paper gives an overview of the resources available from the IOP website. The core text includes around 80 articles which are co-authored by leading experts, arranged in themes, and can be used flexibly to provide a range of alternative approaches. Many of the articles include interactive simulations with accompanying activities and problem sets that can be explored by students to enhance their understanding. Much of the linear algebra needed for this approach is included in the resource. Solutions to activities are available to instructors. The resources can be used in a variety of ways, from being supplemental to existing courses to forming a complete programme.\nFunding This research was funded by the Institute of Physics. History School Science Department Physics", "pred_label": "__label__POS", "pred_score_pos": 0.6985057592391968} +{"content": "Teachers work tirelessly to instill critical knowledge, skills, and values in the world’s upcoming generations. Unfortunately, this essential duty comes with a price. It is not uncommon for educators to find themselves on the other side of a lawsuit that costs them their savings, their job, or even their licensure.\n1. Allegations of Sexual Misconduct\nAllegations of inappropriate student-teacher relationships have made headlines for decades. While these allegations are often, unfortunately, true, false accusations are equally prevalent. Having educator liability insurance coverage can help teachers feel supported should they ever find themselves in this distressing situation.\n2. Lawsuits Regarding Quality of Education\nIf a family feels that their child did not receive an adequate education, that family may choose to take legal action against specific teachers, the school itself, or even the entire district. While these cases are often settled out of court, insurance policies can cover the ensuing fees for legal representation.\n3. Liability for Inadequate Student Accommodations\nSome students with disabilities require specific accommodations during their time at school. If a teacher or school does not honor these accommodations, that family is entitled to sue for the physical and emotional impact this has on students.\nToday’s teachers wear many hats, and the stress of the job is overwhelming even without the additional worry of career-ending accusations. By maintaining adequate insurance coverage, however, educators can take at least one stressor off their overloaded plates.", "pred_label": "__label__POS", "pred_score_pos": 0.9548761248588562} +{"content": "Written By: Joseph W. Goetz, Yoko Mimura, Miti P. Desai, and Brenda J. Cude\nThe current study explored differences in financial behaviors between college students in Georgia who retained the merit-based HOPE Scholarship and those who lost it. Logistic regression was used to analyze data from a sample of 557 undergraduate students from a large southeastern university. Students who initially had HOPE Scholarships but lost them were less likely to have used recommended financial management practices and had higher credit card as well as student loan debt than students who retained HOPE Scholarships. The results suggest that students who had lost the HOPE Scholarship may be more financially vulnerable than initially expected, particularly given their higher levels of debt and maladaptive financial management practices. Key Words: college students, financial behavior, financial managementDownload Journal", "pred_label": "__label__POS", "pred_score_pos": 0.5850542783737183} +{"content": "In recent years, offshore renewables have been facing rapid technology cost reductions and significant uptake in various markets. New capacities are emerging elsewhere despite the North Sea and nearby Atlantic Ocean having over 90 percent of global offshore wind installations. New technologies like floating wind installations are rapidly increasing the economic potential of offshore renewables. […]", "pred_label": "__label__POS", "pred_score_pos": 0.6800300478935242} +{"content": "Apart from being a humanitarian crisis, the biggest fallout of COVID-19 is its global disruptions of economic activity. Today, the world is in a double shock of supply and demand struggling to push the “reset” button. As losses mount and uncertainties surrounding the economy and public health intensifies, a global perspective and best practices on how to face these challenges become imperative.\nAs a trusted risk advisor, Marsh organized a session where a panel of experts provided insights on how to secure receivables and safely sustain and expand business.", "pred_label": "__label__POS", "pred_score_pos": 0.9994125366210938} +{"content": "The key gauge of manufacturing PMI (Purchasing Managers’ Index) China registered a dip of 50.9 in June 2021. In the last month, it was 51. This is because the production got slowed due to the poor power supply, which halted the production. The official data released on Wednesday exhibited the facts. The reading was clocked above the expectation of the market forecast carried by Nomura, which was 50.7.\nThe NBS’s (National Bureau of Statistics) Zhao Qinge said that the PMI of manufacturing might have slipped by 0.1 per cent, but it was following the expansion zone. That displayed that manufacturing was showing steady growth.\nNotably, any reading beyond 50 is an indication of activities expanding. However, the reading less than that is contradictory. The manufacturing PMI has remained above 50 for a record sixteen months without a miss.\nThe chief China economist at Nomura, Lu Ting said that moderation resulted from a drop in the production subindex. The rebound of new orders and employment subindices also triggered it more than offset, she added.\nIn June, the production subindex dropped to 51.9. It was lower than 0.8 percentage points compared to 52.7 in May. Zhao said that the shortages of coal, chip and power supply lead to the situation. The chief economist of Hang Seng Bank China, Wang Dan, believed that the supply shortage would continue until the end of the year. Moreover, the global shortage of chips and other industrial inputs would put a bar on the production growth of the nation.\nWang noted that the resurgence of COVID-19 in major Asian countries, including India, has now led to global demands relies on China for meeting the supplies. However, China’s supply issues can be resolved once other Asian countries recover to the full capacity of their production capacities. He sounded optimistic estimated better performance the next year.\nThe subindex of new orders hiked to 50.5 in June in comparison to May, which was 51.3. However, the new export subindex in May was 48.3, which slipped to 48.1 in June.\nThe slip indicated the weaker sequential momentum, as per Lu. It would have been caused due to congestion at South China ports.", "pred_label": "__label__POS", "pred_score_pos": 0.6097668409347534} +{"content": "A decision to end a relationship (both with a person of the same or the opposite sex) sometimes requires a proper legal regulation of relations between former partners / spouses and their children. Such regulations include, among others, divorce proceedings, establishing custody over children, contacts with children, divisions of property or awarding alimony and support. In some cases, these activities should also include securing rights of parents’ new partners, including the right to maintain contacts with their partner’s children.\nOur experience:\n– divorce proceedings;\n– proceedings aimed at establishing a custody over children and contacts with children; – division of property and establishment of property separation; – alimony and support proceedings; – preparation of voluntary parental agreements between biological parents and social parents.", "pred_label": "__label__POS", "pred_score_pos": 0.9940186738967896} +{"content": "You are not permitted to download, save or email this image. Visit image gallery to purchase the image.\nDoes gardening count as a moderate workout?\nIn the fitness world, it's an ongoing debate.\nYes, say some people: the walking, bending, digging and pruning is sufficiently strenuous to gain fitness benefits.\nNo, say others: more vigorous movement is needed. A recent study might put this discussion to rest, at least for older people.\nResearchers from Kansas State University studied the gardening habits of 14 men and women aged 63 to 86.\nThey noted how much time the participants spent on tasks such as watering, walking, cleaning tools, weeding and harvesting.\nHeart rates and oxygen uptake were measured to determine how hard they worked.\nStandard measures that rate the intensity of physical activities were used to evaluate the work. Activities such as digging, raking and mulching used upper and lower body muscles and scored as moderate-intensity exercise.\nMixing soil and hand weeding engaged only the upper body and were scored as lower intensity.\nOverall, the gardeners' activity was of moderate intensity but changed with the seasons.\nThe study, published in the journal HortTechnology, noted that older people often become sedentary - and that the dynamic qualities of gardening could help them stay active.\n-Jeannine Stein.", "pred_label": "__label__POS", "pred_score_pos": 0.9731760621070862} +{"content": "Slide 3: We live in an unusual, stable climate\nDuration: 00:00:58\nNotes:\nThe earth's atmospheric composition and temperature change over the long term. This graph details variations over the last 500 000 years. It is clear from the graph that the current period (approximately the last 10 000 years) has been unusually climatically stable. However, it is clear that there has been considerable variation over the last 500 000 years, following a pulsed trend typical of a system varying around an equilibrium value. It is important to note that the Holocene (recent history) is particularly warm in relation to the planet's history - Earth is generally better adapted to a cool climate.", "pred_label": "__label__POS", "pred_score_pos": 0.9231918454170227} +{"content": "Aza-boron-diquinomethene complexes bearing\nN-aryl chromophores: synthesis, crystal structures, tunable photophysics, the protonation effect and their application as pH sensors† Abstract\nA series of aza-boron-diquinomethene complexes (\n1a–1e) bearing different N-aryl chromophores were synthesized and characterized by multinuclear NMR spectroscopy, X-ray crystallography, optical absorption and emission spectroscopy, and elemental analysis. These robust thermal complexes possess tunable intense luminescence from blue to red with relatively high emission quantum yields. The introduction of different N-aryl chromophores into the aza-BODIQU core significantly tuned the emission colors. The relationship between their structures and properties was investigated systematically via spectroscopic methods and simulated by density functional theory (DFT) calculations. Additionally, the application of 1c as a pH sensor with a remarkable colour-changing property has been investigated. All these results indicate that these complexes exhibit robust thermal stability, tunable photophysical properties, relatively high photoluminescence quantum yields and protonation effect, making these complexes potential candidates for pH sensors, bioimaging probes and organic light-emitting materials.", "pred_label": "__label__POS", "pred_score_pos": 0.9521424770355225} +{"content": "Exclusive: Boosting stadium security with AI technology Share this content Mark Zayek, COO of Astrophysics Inc. discusses how the use of Artificial Intelligence can help to improve stadium security.\nAs we pass the one year anniversary since the start of the coronavirus pandemic, our daily lives still remain dramatically disrupted. Travel remains low from pre-pandemic highs, corporations are slowly bringing employees back to their offices and stadiums remain quiet as sporting events, concerts and live performances gradually open back up. Live events have started again and their return will mark a shift away from a year that centred on global health concerns and back towards pressing security issues. As people gather again for live events, stadiums and arenas will once again be tasked with protecting fans, athletes, performers and their staff at these potential targets.\nArenas can be challenging locations to properly protect. They have multiple entrances for both the general public and players, performers and staff; each entrance requires security checkpoints that prevent threats from entering the facility. Layouts may change from event to event, requiring staff and equipment to relocate to accommodate shifting security procedures. On top of it all, threats are constantly evolving, requiring security personnel and their systems to stay up-to-date with the latest screening and threat identification tools.\nThere is one stadium security tool perfectly suited to meet all these challenges: x-ray screening. These non-intrusive, high-throughput scanners can quickly evaluate backpacks, purses, bags and deliveries to locate threats and verify shipping manifests. Scanners equipped with enhanced mobility packages can relocate quickly and help security personnel adjust to changing security needs. The latest technologies, including Astrophysics’ Artificial Intelligence (AI) software, decreasing the need for extra security personnel while improving threat detection and ensuring throughput is not impacted during popular events.\nIn fact, Astrophysics offers an x-ray scanner designed specifically to protect stadiums and arenas that includes all these advanced features: the XIS-6040SE with AI. This modular scanner, based on our most popular design, is ideally suited to protect fans, performers and staff at live events, for the reasons we will explore below.\nBuilt for stadium security\nStadiums are fast-paced, high-energy environments. Security scanners need to be designed to operate and keep pace with all the activity within those locations and the XIS-6040SE is perfect for that mission.\nThe XIS-6040SE is a checkpoint scanner designed to screen backpacks, parcels and packages for hidden threat objects. Its compact design allows for deployment in the tightest locations and it comes equipped with the latest advanced imaging technology including colour imaging and material discrimination.\nThe XIS-6040SE is also optimised for operating in stadium environments. It is designed with a mobility package for easy relocation. Its shock-absorbing wheels, stainless steel handles and collapsible roller table all facilitate quick and easy movement around any facility and allow for rapid redeployment to new checkpoints. Its spill-resistant conveyor belt protects its critical components from liquids, ensuring neither security personnel nor exciting fans accidentally damage this critical equipment.\nThese features pair well with the scanner’s compact frame, helping it fit through narrow doorways and move down small hallways. This small footprint allows it to operate in nearly any location and serve as the focal point of any security checkpoint. In arenas, speed and flexibility are critical. The XIS-6040SE is ideally designed for these environments, delivering critical security screening when and where it is needed.\nAdvanced Artificial Intelligence imaging technology\nAll Astrophysics’ scanners come equipped with industry-leading imaging technology. High-resolution images are displayed with 24-bit colour. Combined with enhanced material discrimination, operators can quickly identify an object’s material composition, helping determine whether it is harmless or threatening. Enhanced Imaging (EI) and high-contrast analysis deliver clear, precise images, making sure no threat escapes security personnel detection.\nThe key element of effective security screening has traditionally been the use of well-trained personnel operating the equipment. Highly trained screeners understand the scanner’s features and can leverage its capabilities to quickly screen numerous objects without slowing throughput. The coronavirus pandemic has dramatically impacted facilities’ ability to recruit, train and maintain effective screening personnel. Budgets were cut while arenas and stadiums sat empty and personnel who contracted COVID-19 had massive negative impacts on security operations.\nThe challenge in stadiums and arenas often comes down to understaffed or undertrained security personnel. These personnel may not be familiar with how to operate x-ray scanners and received minimal training in how to effectively screen objects. However, rapidly improving technology, including advanced neural networks and artificial intelligence, are now making those concerns a thing of the past.\nAstrophysics’ AI software supports and supplements security screening with even the most novice personnel. This fully-integrated screening software provides automated threat recognition and is available on all Astrophysics units. This cutting-edge technology is a game-changer for critical infrastructure checkpoint security.\nThe AI software is fully adaptable and learns how to recognise and better identify threats as it analyses more scanned images. The system is also so adept at finding hidden objects, it can identify threats that are hidden, rotated or partially obscured, ensuring no object escapes detection. Once a suspicious object is located, whether it might be a knife, gun, or liquid container, the software highlights its location on screen and notifies security personnel that a physical inspection is needed. Best of all, it does not require extensive training for personnel – simply activate a scanner equipped with Astrophysics’ AI and start screening.\nA revolution in X-ray security\nThe XIS-6040SE with AI will revolutionise x-ray screening, especially for stadiums and arenas. As these locations reopen for live events, they will need to balance not only keeping performers, fans and their staff safe, but also juggle costs with limited revenues as event capacities slowly increase. Time and resources will be limited, making AI software a key tool in ensuring screening checkpoints are ready for the rush of fans returning for live events.\nAI software will not pry into athlete’s personal belongings – it simply scans an object, looks for identifiable threats and then quickly moves on to the next object to scan. The AI software does not differentiate between fans, performers or staff – it takes the same objective approach to every object it scans. It eliminates opportunities for profiling and removes biases from the screening process, ensuring everyone is treated the same as they enter a facility.\nAs capacities expand, the arenas will then need to adjust their security plans and checkpoint layouts to accommodate larger crowds. Different events, such as sporting events, concerts and live performances, will require different checkpoint configurations to manage throughput while screening every fan that enters the facility. If an arena hosts a sporting event one night and then immediately follows it up with a concert the next, screening personnel can efficiently relocate the scanners before the first fan arrives for the new event.\nStadium security checkpoints are the perfect locations for the compact, mobile XIS-640SE. When paired with AI technology, even the least experienced security operator can quickly and effectively screen fans and staff at a very high throughput, without sacrificing performance or overall security. Facilities can also save on labour costs by not needing to worry about hiring additional staff or training them on the new system. This extra benefit helps drive home how critical x-ray security is for stadiums and arenas and how easily it can be incorporated into existing security budgets.\nThis article was published in the May 2021 edition of International Security Journal. Pick up your FREE digital copy on the link here", "pred_label": "__label__POS", "pred_score_pos": 0.6730501651763916} +{"content": "This 30-minute listen is a great introduction to us and our work.\nCategory Archives\nPodcast\nThe Ciencia, Fe y Esperanza (i.e., Science, Faith, and Hope) project addresses the disconnection between faith and science in the Latinx community with the intent of creating a safe space for dialogue, providing education, and encouraging young people to see STEM careers as vocational callings.\nOur own Greg Cootsona discusses the supposed conflict between science and religion in Princeton Theological Seminary’s Podcast, The Distillery.\nRachel Held Evans, who passed away in 2019, was a leading voice for progressive Christians and found that integrating science was critical for keeping her faith. In fact, when we surveyed our audience in 2020, we found she was one of the top voices who had influenced our respondants.\nAfter decades of analyzing the religious perspectives of scientists and the views religous people have about science, Elaine Howard Ecklund has now written a book for the church. In it, she offers eight shared values that can help advance the conversaton about science in our churches.\nDisciple Science is an organization dedicated to creating quality videos that would “reach those who feel forced to choose between science and Christianity and invite them to follow Jesus, know creation, and grow in faith.”", "pred_label": "__label__POS", "pred_score_pos": 0.7373536825180054} +{"content": "Abstract\nThis study addresses the initiation mechanisms of mass failures on clinoform foresets. Previous studies have created mass flows by releasing dense water-sediment mixtures into standing water, thus imposing the initial conditions for the mass failures rather than allowing them to form on their own. Para-meters such as the density, composition and initial momentum of the failures are pre-determined, precluding observation of the factors that set them initially. This study uses a new experimental method that allows a range of mass failures to self-generate. Building a clinoform using a cohesive mixture of walnut-shell sand and kaolinite allows the foreset to build up and fail episodically, generating mass failures. Slopes undergo a series of morphological changes prior to failure, creating a concave shape that becomes exaggerated as deposition continues. This morphology leaves the slope in a metastable state. Once the slope is destabilised, failure is initiated. This study investigates the effect of clinoform progradation rates on failure size and frequency by conducting experiments over a range of water and sediment discharge rates. Neither failure size nor failure frequency changes with discharge rate; instead, increases in sediment supply are taken up by changes in the partitioning of sediment between the steep upper foreset and the more gradual delta-front apron (toeset) below. Sediment is delivered to the delta-front apron by a form of semi-continuous slow creep along the foreset. This slow creep is a failure mode that has not received sufficient attention in the submarine mass-flow literature. The independence of failure size and frequency from sediment supply rate suggests that the presence of mass-failure deposits does not provide information on the rate of sediment delivery. If these relations hold at field scales, this would imply that individual mass failures are relatively insensitive to changes in water and sediment supply.\nBibliographical notePublisher Copyright:\n© 2014 International Association of Sedimentologists.\nKeywords Clinoform progradation Cohesive sediment Sediment transport Slow creep Turbidity currents", "pred_label": "__label__POS", "pred_score_pos": 0.5933388471603394} +{"content": "The risks of wildfire are clear, but in between individual hardship and broader economic impacts, many other costs are typically not accounted for by investors.\nChina is a double-edged sword: it is the world-leading renewables developer, installing more than double the gigawatt capacity of its nearest competitor over the past decade both in terms of wind and solar power, but at the same time it has seen the highest coal capacity additions over the same period – nearly quadruple that seen in India.\nWhile one in every three dollars in the US is managed following sustainable investment strategies, and the nation is the world’s largest country issuer of green bonds, there remain significant opportunities for growth. Early signs indicate the Biden administration could provide a ‘turbo boost’.\nView the RI team’s report from the second quarter of 2021\nOur UK Real Estate strategy to reach net zero by 2050 addresses a major source of risk for commercial property investors and aims to deliver better outcomes for all stakeholders\nThe European Commission has unveiled its Fit for 55 roadmap setting out the transformation to deliver the European Union’s 2030 target of reducing net greenhouse gas emissions by at least 55% by 2030.", "pred_label": "__label__POS", "pred_score_pos": 0.5539529323577881} +{"content": "The World Health Organisation (WHO), has disowned reported high ranking for Nigerian government’s COVID-19 response.\nWHO country representative, Walter Kazadi Mulombo who gave the clarification on the sidelines of the commencement of Nigeria’s second phase of the COVID-19 vaccines programme at the Federal Medical Centre, Jabi, on Monday, said the organisation had not ranked countries based on their response to the COVID-19 pandemic.\nhe said. “Some independent media analysis had previously presented a ranking for top 10 countries, with Nigeria appearing on the fourth position. It should be noted, however, that this is not a WHO ranking,”\nMulombo, however, noted that Nigeria had mounted one of the most effective responses to COVID-19, putting in place measures.\nThe representative added;\n“As I always mentioned at different fora, vaccines are a critical tool in the battle against COVID-19. These vaccines are safe and effective and will be the game-changer. But for the foreseeable future, we must continue wearing masks, physical distance, and avoid crowds.”\nHe also noted that Nigeria is currently experiencing the third wave of COVID-19 outbreaks.\nThe Global Normalcy Index ranked Nigeria fourth out of 50 countries on the Economist’s Global Normalcy Index. The index sought to establish which nations were returning to their pre-pandemic ranges by classifying nations on eight metrics: time away from residence, retail, workplace use, public transportation, site visitors, air journeys, cinema visits, and sporting occasions.", "pred_label": "__label__POS", "pred_score_pos": 0.9873104691505432} +{"content": "Students look for professional\ndissertation literature review writing help online. After enrolling in a postgraduate program, writing a dissertation is inevitable. A dissertation chapter two is a section where students must supply the supervisor with a summation of the significant past scholarly works. This past literature must pertain to the dissertation subject area, making writing such a section complicated & tedious. Besides, writing an excellent literature review provides a student’s dissertation with relevant ideas; any left gaps left in the previously done research can be identified & filled. However, this isn’t an easy task that can take less time since gathering literature on a topic demands extensive focus and concentration.\nAt times, students feel the need to seek experts who can provide\nfirst-class dissertation chapter two writing services. The assistance students require throughout the draft is provided by expert writers; as this is a section that can make or break a dissertation. Without a doubt, being a postgraduate student is stressful. However, students can make their academic lives easier by engaging the best writers. That’s the smart move that many students take; especially when they can’t figure out the best approach for writing a dissertation literature review. In addition, a dissertation has various chapters, and the most intricate of all is a literature review. Hence, a literature review can be strenuous and tasking for students writing dissertations for the first time. Steps to Follow When Writing a Dissertation Literature Review\nStudents rely on\nprofessional dissertation literature review writing services, given the challenges associated with the writing process. Students find the process tiring, and the below steps can portray the intricacy of the process. First, search for meaningful information– before the data gathering process begins, it’s crucial to define the topic. That’s to assist you in gathering literature that relates to the research problem. Proceed to evaluate & select suitable sources– the topic is widely researched, therefore reading everything written on it may be challenging. Evaluate the most relevant sources to the research question. It’s relevant to identify debates, themes, & gaps– to begin organizing a lit review’s argument & structure; it is crucial to understand the relationship between the consulted sources. Outlining the literature review’s structure is another requirement– there are various approaches towards organizing a lit review by strategizing how to begin and end. Commence the literature review writing process-like any other academic paper; a dissertation literature review must include all chapters. All sections must be relevant, coherent, and professional.\nAll the chapters of a dissertation lit review should be clear, precise & focused. A professional lit review must clearly outline the main topics covered in a dissertation. However, writing a dissertation to many is complex and daunting; given that the process demands proper research and writing skills to ensure that the project is complete and professional. Besides, this is a crucial summation of external authors and theorists to the topic; making a dissertation lit review quite challenging to handle.\nWhat’s The Purpose of Writing a Great Literature Review Chapter?\nIf a student aims at earning high grades and secure a postgraduate degree; writing an outstanding dissertation with a relevant lit review is crucial. A quality literature review must reflect on a student’s unique & ideal perspective on a topic, making it necessary to seek the\nbest dissertation chapters writing help. In addition, to ensure that the people evaluating a dissertation appreciate its context, it’s relevant to provide them with the necessary information reflecting on past researchers’ general arguments & results. Writing an appropriate dissertation literature review helps students achieve the following; One can effectively demonstrate their passion and experience towards working hard for a Ph.D. degree. A student gets the chance to educate others through portraying the general knowledge regarding the dissertation topic one is dealing with. Besides, this helps them understand the relevance of their ideas. It is easy to generate a project’s context on any subject, as a dissertation is an alternative voice on an ongoing argument.\nIf writing a dissertation is hard for a student, there’s a high probability that the lit review is to blame. Therefore, seeking\nprofessional dissertation literature review writing help is crucial. Regarding the size of a dissertation literature review; it is a requirement students write a project that ranges between 1000 and 3000 words. Students consult qualified dissertation chapter two writers to write this critical chapter to completion. Why Seek Our Thesis-Dissertation Lit Review Writing Services\nFor decades, students have benefited from our\nexcellent dissertation lit review writing help, as they receive the best guidance to deal with the tough ordeal. Every student wishes to gain their instructor’s appreciation; however, this is only possible if the assignment is informative, engaging, and well-organized. With a relevant literature review, a student can prove the investment of their hard work, time, and skills in writing the project. Should a student feel less confident about their work, we are a trusted and reliable firm. When looking for a relevant way of dealing with your challenging task, students can consult us for the best writing guidance.\nWhat we offer is nothing short of quality services to assist you in meeting professional writing standards. When your quote to us reads, “\nI need help to write my dissertation chapter two,” we will meet your demands fully. As a global help provider; we ensure to vet our writers before employing them to create a team that guarantees the best services. Furthermore, we invest in the best plagiarism checking technologies to provide you premium quality & ensure 100% plagiarism-free writing help. Like various academic papers, a dissertation literature review must contain all chapters. It is easy to write a project with a quality introduction, body, and conclusion by seeking the best assistance with writing a dissertation lit review. Finding it Hard to Write a Dissertation Literature Review?\nWhen students face challenges when writing a literature review, the best alternative is seeking help. At our firm, we understand the plight of students; therefore, we provide a\nfirst-class dissertation lit review writing service. We are aware, creating a suitable literature review comes with a set of challenges. Besides, we understand the importance of a dissertation literature review to you; the reason why we strive to meet your demands beyond expectations. With a dedicated team of qualified writers who hold Ph.D. and master’s degrees across various academic fields; helping you write a profound dissertation chapter two is possible and guaranteed.\nHence, we will begin by assisting you in identifying the best research sources to prepare a good, relevant, & credible project. More importantly, our primary focus is the quality of your work; therefore, you can trust us to provide top-notch writing guidance.\nDissertation Thesis Help offers help at the right time, at affordable prices that suit your budget. If you need expert help to write a dissertation chapter two, we are here for you.", "pred_label": "__label__POS", "pred_score_pos": 0.7490490674972534} +{"content": "JAKARTA, 07 OCTOBER, 2021 - Indonesia's leading e-wallet DANA today expands a new added value for its users by providing phone screen protection insurance with Singapore-headquartered regional insurtech Igloo. Through this partnership, DANA aims to offer its over 80 million users an affordable microinsurance solution through a digital channel to purchase mobile phone screen protection and make a claim, all in one app.\nUnderwritten by PT Jasa Asuransi Indonesia-Jasindo and distributed by PT Insco Multi Pratama, plans start from as low as Rp500 and cover up to a maximum of Rp200,000 for cracked phone screens on both new and used mobile phones. To activate the protection, users can navigate to \"DANA Siaga\" in the DANA app to select a plan that suits their lifestyle or select the add-on when completing their purchase of mobile recharge. Together with Igloo, DANA has introduced a digital solution \"As a lifestyle-based digital wallet application, DANA offers a one-stop solution to accommodate the various characteristics and needs of its users all across Indonesia. It includes expanding collaboration and partnerships with Igloo to protect users' phones, and their mobile-based activities are hassle-free. Moreover, the need for microinsurance is in high demand. Based on the Financial Services Authority (OJK) data alone, the development of microinsurance as of June 2019 already has 22.1 million policyholders or participants. Therefore, we warmly welcome this partnership to continue to encourage the advancement of insurance in Indonesia and increase financial inclusion,\" said Vince Iswara, CEO & Co-Founder of DANA. The new protection aligns with DANA's commitment to continuously updating and improving the user experience in digital transactions through the DANA app to reach more users throughout the nation. DANA has seen growth during the pandemic, with the number of transactions increased by 151% YOY. Referring to data from App Annie – a provider of application analytics and application market data – DANA was the only finance app amongst the Top 10 most downloaded apps in Indonesia across all categories in Q2 2021. It also ranks first in the financial apps category for most downloads (iOS and Android) in Indonesia in Q22021. According to the ‘Southeast Asia (SEA), the home for digital transformation’ report, Indonesia has seen the strongest growth in the region (21 million, equivalent to a 15% growth) with high smartphone ownership (98.2% in Jan 2021). Mobile phones have been a critical tool for merchants and gig workers who run their businesses and become an integral part of consumer's social life. \"Dana has played a pivotal role in driving digital adoption of financial services amongst the Indonesian customers. This trend has been accelerated due to the pandemic with increasing reliance on cashless payments from utility payments to investments. Igloo is proud to collaborate with Dana to extend its digital solution of micro insurance portfolio to Dana consumers in an intuitive and affordable fashion.” said Raunak Mehta, Igloo Chief Commercial Manager. This initiative marks Igloo’s second partnership with a mobile wallet brand after GCash, in the region, strengthening its presence to provide affordable and accessible insurance for the masses by working with partners from diverse verticals. Igloo had secured partnerships with industries that range across e-commerce, logistics, automobiles, transportation, telecommunication, banking, travel and hospitality and the gig economy. In Indonesia, aside from DANA, Igloo has partnered with the country’s largest e-logistics platforms, Ritase, e-commerce company, Bukalapak, home and business appliances solution provider, Modena, and freight logistics marketplace, Kargo Technologies. Regionally, Igloo also works with food delivery company, foodpanda, SEA’s leading e-commerce platform, Shopee, on-demand and SEA's fastest-growing hotel management platform RedDoorz.", "pred_label": "__label__POS", "pred_score_pos": 0.8366483449935913} +{"content": "The increasing demand for micromobility services for first- and last-mile connectivity, cost-effective and convenient mobility options, and need for curbing urban traffic congestion are the major factors driving the growth of the micromobility market in Malaysia. Due to the aforementioned factors, the industry is projected to generate $4,549.8 million revenue in 2030, advancing at a strong CAGR, of 99.9%, during the forecast period (2021–2030).\nThe COVID-19 pandemic had a substantial impact on almost all industries, including micromobility, in 2020. However, the micromobility industry has begun to show the sign of recovery and it is expected to stabilize in coming years. In Malaysia, lockdowns influenced customer behavior and mobility patterns, with more consumers preferring micromobility over public transit, as shared transportation is seen as a health risk. To reduce the threat of infection, there has been a significant movement away from shared mobility and public transportation. Thus, people seem to prefer single occupancy options.\nThe Malaysian micromobility market is categorized into e-scooters, e-bikes, e-mopeds, e-pods, bikes, and scooters, on the basis of vehicle type. Among these, the e-mopeds category is projected to exhibit the fastest growth during the forecast period. This can be mainly ascribed to the fact that this vehicle type is widely used in the country, owing to the ease of operation, convenience, economical nature, and environment-friendly mobility option.\nMoreover, the Malaysian micromobility market is bifurcated into first- and last-mile and multimodal, on the basis of model. Between the two, the first- and last-mile category accounted for larger market share in 2020. This is primarily due to the surging demand for micromobility services for first- and last-mile traveling. Moreover, users of other popular mobility services, such as ride hailing, carsharing, and ride sharing, do not utilize them for shorter distances, as they are more expensive. As a result, the micromobility services is an excellent and cost-effective choice for such users.\nFurthermore, the micromobility market in Malaysia is categorized into docked and dockless, on the basis of sharing system. Out of these, the dockless system accounted for larger share in the market in 2020. This is attributed to the more convenient features and less effort requirement in renting vehicles in this sharing system, which is also offering high flexibility in parking.\nKey players in the Malaysian micromobility industry have been involved in their business expansions, in order to gain a significant competitive advantage in the market. For instance, in July 2019, Beam Mobility Holdings Pte Ltd., an e-scooter sharing service provider, announced the expansion of its operations in Malaysia (Kuala Lumpur), Australia (Adelaide, Brisbane, Canberra, Melbourne, Sydney, and Townsville), South Korea (Seoul, Incheon, Gyeonggi do, and Daegu), New Zealand (Auckland, Christchurch, and Wellington), and Singapore.\nSimilarly, in January 2019, Tryke Transportation Sdn Bhd (Tryke) started its e-scooter sharing service in Cyberjaya, Malaysia, with a fleet of 70 e-scooters. In November 2019, it expanded its services in the city, owing to the robust infrastructure, lower road traffic, strong support from stakeholders and local authority, and presence of a vibrant community of students, young professionals, and tourists.\nSome of the key players in the Malaysian micromobility market are Anywheel Pte Ltd., Neuron Mobility Pte Ltd., Grab Holdings Inc., Beam Mobility Holdings Pte. Ltd., Ecocana Sdn Bhd, Falcon Ride WLL, Yadea Technology Group Co. Ltd., Giant Co. Ltd., Merida & Centurion Germany GmbH, Vmoto Limited, Segway Inc., and Tryke Transportation Sdn Bhd.", "pred_label": "__label__POS", "pred_score_pos": 0.9459930062294006} +{"content": "China's resilient aviation market will create new commercial aircraft demand valued at 1.47 trillion U.S. dollars over 20 years, said Boeing's latest market forecast released in Beijing Thursday.\nChina's economic vitality and recovering air travel demand will enable the country's airlines to purchase around 8,700 new aircraft over the 2021-2040 period, said the China forecast, which is part of Boeing's 2021 Commercial Market Outlook.\nOver 20 years, the Chinese market will receive some 6,500 single-aisle planes and 1,850 widebody aircraft, showed the U.S. planemaker's annual long-term demand forecast for commercial airplanes and services.\n\"The rapid recovery of Chinese domestic air travel highlights the country's economic vitality and resilience. Notably, the underlying demand from international long-haul travel and air freight transport will boost the widebody deliveries,\" said Richard Wynne, managing director of China Marketing at Boeing Commercial Airplanes.\nThe widebody deliveries, including passenger aircraft and freighters, account for 44% of the Chinese market demand by value, Wynne added.\nOver the next 20 years, China is also expected to create a commercial aviation services market valued at around 1.8 trillion U.S. dollars, the forecast showed.\nChina's aviation sector has remained the world's second-largest in terms of passenger trips for 15 years.\nThanks to the country's economic resilience and effective pandemic control, China is leading the global civil aviation industry in recovering from the COVID-19 impact, according to the Civil Aviation Administration of China (CAAC).", "pred_label": "__label__POS", "pred_score_pos": 0.868387758731842} +{"content": "Women are still vastly underrepresented in the science, technology, engineering and math (STEM) workforce. Analysis conducted in 2018 by IU Bloomington Assessment and Research found that female students are at a higher risk of leaving STEM disciplines than male students at IU Bloomington. IU Bloomington’s Office of Engaged Learning focuses on ensuring that female students develop the skills and experiences to thrive in STEM fields, while finding a sense of belonging while on campus through community, faculty mentorships, and the summer research program.\nThe Advancing Women in STEM fund enhances access for female-identifying students to explore and pursue STEM-related studies and opportunities. In doing so, students are positively impacted in their social belonging and retention in STEM disciplines.", "pred_label": "__label__POS", "pred_score_pos": 0.9415355920791626} +{"content": "Forming Focused Questions with PICO: PICO's Limitations PICO's Limitations\nWhile PICO can be a convenient acronym for building clinical questions, the framework has several limitations. This page lists these limitations and suggests ways to address them.\nPICO Privileges Interventions\nPICO primarily centers on intervention (or therapy) clinical questions. It can be less suitable for other question types.\nUse this worksheet (Word document) from Sonoma State University to help you structure your non-therapy PICO question. Read more about this limitation in the research published by Xiaoli Huang, MLS, Jimmy Lin, Ph.D., and Dina Demner-Fushman, M.D., Ph.D. in their article titled \"Evaluation of PICO as a Knowledge Representation for Clinical Questions.\" PICO Privileges Experimental Research\nPICO privileges research that is experimental or observational in nature. It does not account for complexities like considering feasibility, context, and sociocultural acceptability.\nTo broaden beyond the PICO elements, consider other question frameworks. Read more about this limitation in the research published by Andrew Booth, Jane Noyes, Kate Flemming, Graham Moore, Özge Tunçalp, and Elham Shakibazadehin their article titled \"Formulating Questions to Explore Complex Interventions within Qualitative Evidence Synthesis.\"\nPICO Privileges Dominant Voices\nPICO is a tool used in evidence-based practice (EBP), which is an integration of clinician expertise, patient preferences and values, and the best available research evidence. EBP defines evidence according to a pyramid with randomized controlled trials recognized as the highest level of primary evidence. This hierarchy of evidence can exclude the voices of minority populations and the interests of those in non-dominant populations. Thus, EBP, while seemingly objective, often reflects White voices and assumptions of the majority. Therefore, the use of PICO to frame literature searches may prove successful for questions with dominant populations and result in evidence gaps for non-dominant populations.\nTo expand literature searches to include more voices, search databases that reflect a global perspective. Expand beyond peer reviewed journal literature to include dissertations, reports, blogs, social media, websites, and others. Experiment with broadening your PICO elements, such as by including a larger population. Contact a health sciences librarian for additional support.", "pred_label": "__label__POS", "pred_score_pos": 0.890945553779602} +{"content": "Back in 2005, I wrote that when it comes to spending, \"Congressional Republicans Make French Socialists Look Like Ronald Reagan.\" Looking back now, from the perspective of fiscal prudence, those were the good old days. Yet, as irresponsible as Republicans have been with our finances since then, today's Democrats seem committed to making the spendaholic GOP look like Uncle Scrooge.\nLet's recap: The worst of the COVID-19 emergency is hopefully behind us, meaning the country should focus on recovery, fully reopening the economy, and returning to work. Government should focus on scaling back emergency programs and reducing the deficit. It's not just the prudent thing to do, it's also what Americans want. According to a recent Pew Research Center poll, 72 percent of Americans view the federal budget deficit as a \"very big\" or \"moderately big\" problem. This concern is more pronounced than that surrounding any issues politicians are focusing on these days, including illegal immigration and crime.\nThey're wiser than most politicians. After spending almost $6 trillion on pandemic-related programs, the deficit is up to $3 trillion from $984 billion in January 2020 (an alarming figure in itself), and our long-term fiscal prospects are looking red. While a fiscal crisis may be a while off, the economic crowding out and distortions produced by high spending and low growth are already upon us.\nHowever, the Democrats controlling the House, Senate, and White House ignore these facts and are pushing through more spending—trying to make many temporary COVID-19 measures permanent programs while expanding existing and already unsustainable programs.\nWeary of the trend, Republicans are presenting a somewhat united front in opposition to the measures. But they're now joined by a few Democrats in both the House and the Senate. Sen. Joe Manchin (D–W.Va.) for instance, announced he wouldn't support the $3.5 trillion tax and spending legislation pushed through the reconciliation process. He also noted that he wouldn't vote for a reconciliation bill that's more than $1.5 trillion. That number would increase this fiscal year's spending to a whopping $5 trillion.\nWe should all be grateful to those resisting the entitlement explosion. While beneficiaries of those programs (including federal paid leave, universal pre-K, and expanded child tax credits) may like the upfront benefits they will get, studies have shown that these measures can backfire and hurt those they're trying to help. For instance, European governmental paid leave programs have resulted in outcomes that include lower pay, fewer promotions, and lower employment for beneficiaries.\nThe progressive members of the Democratic Party disagree. Hence, the political pressure they're putting on the opposition by refusing to vote on a separate $1 trillion infrastructure bill negotiated with Republicans by Manchin and Sen. Kyrsten Sinema (D–Ariz.) until they have an agreement on passage of the $3.5 trillion one. Never mind that as\nThe Wall Street Journal rightfully noted the legislation is a \"once-in-a-century bipartisan infrastructure bill\" and is supposedly a priority on both sides of the aisle.\nAnd if that blackmail doesn't work, they want to trick them into accepting the entitlement expansion by using some budget gimmicks meant to create the illusion of a reduced cost. For instance, speaking on CBS' \"Face the Nation,\" New York Rep. Alexandria Ocasio-Cortez (D–N.Y.) noted that \"Washington math is notoriously funny…one of the ideas that is out there is fully fund what we can fully fund, but maybe instead of doing it for 10 years, you fully fund it for five years.\"\nProgressives are lashing out at the ignominy that some members of Congress are still allowed to disagree with them and that a radical transformation of American welfare spending isn't easier. But Manchin's $1.5 trillion compromise is enormous. Also, as the Manhattan Institute's Brian Riedl reminds us, it's not as if Manchin isn't himself a big-government guy. Riedl writes in the\nNew York Post, \"Manchin already voted for the $1.9 trillion stimulus bill in March, and helped craft the $550 billion infrastructure bill that passed the Senate. He also voted for a budget resolution that increases the discretionary spending baseline by $1 trillion over the decade.\"\nDemocrat-driven opposition to this spending expansion should give everyone pause, rather than incite the fury it has unleashed. At the very least, Democrats should take some time to answer Manchin's valid point that \"spending trillions more on new and expanded government programs, when we can't even pay for the essential social programs, like Social Security and Medicare, is the definition of fiscal insanity.\" Indeed, we're definitely not in 2005 anymore.\nCOPYRIGHT 2021 CREATORS.COM", "pred_label": "__label__POS", "pred_score_pos": 0.7016799449920654} +{"content": "On June 4th, The UN High Commissioner of Human Rights released a scathing report on the human rights violations present in the Philippines’ war on drugs. The report called for an immediate and independent domestic investigation into widespread allegations of unlawful civilian killings and severe violations of international human rights laws by state-sanctioned forces. Charges included the false planting of evidence, the use of harmful rhetoric by state officials promoting violence against drug users, and blatant ignorance of the universal right of a fair trial.\nThe UN report highlighted the role of the Philippine government and top national officials in perpetuating the growing human rights crisis in the country. The report concludes that “while there have been important human rights gains in recent years, particularly in economic and social rights, the underpinning focus on national security threats – real and inflated – has led to serious human rights violations, reinforced by harmful rhetoric from high-level officials.” Furthermore, The UN report also emphasized that the violation of human rights have become aggravated over recent years, “successive administrations have mostly employed increasingly violent law enforcement measures and disturbing rhetoric in the campaign against illegal drugs and related crimes.”\nHowever, despite the mounting evidence of human rights violations, the Philippine government continues to deny “that there is a policy to kill people who use drugs and states that all deaths occur during legitimate police operations,” according to the report. The Philippine government can deny such allegations primarily due to a lack of an independent and transparent advisory body over its national security forces.\nThe Philippines’ Inter-Agency Committee was created in 2012 under Administrative Order 35. The committee was assigned to review cases of “extralegal killings, enforced disappearances, torture and other grave violations involving political, environmental, agrarian and labor activists and media practitioners,” according to the UN’s report. However, the agency does not cover drug-related killings, where the majority of wrongful death complaints are found. Additionally, the High Commissioner of Human Rights noted that the Inter-Agency Committee’s effectiveness “remains limited due to its perceived lack of independence, transparency, and powers.” The committee’s disregard for human rights violations in narcotic related crimes and lack of independence allows for Philippine security forces to remain unpunished. Moreover, Philippines’ President Rodrigo Duterte has shown no signs of wishing to increase the committee’s effectiveness.\nPresident Duterte’s 2016 presidential campaign pledged to kill criminals and eliminate corruption in drugs in up to 6 months following his executive appointment. Duterte’s campaign draws from his experience as mayor of Davao City, where “hundreds of extrajudicial killings were documented which, according to the Special Rapporteur on extrajudicial, summary or arbitrary executions, ‘bore officially-sanctioned character’,” according to the UN’s report. Duterte’s mayorship revealed he could sanction murder if the killings were related to drug activity. Without widespread backlash for Duterte’s unlawful methods of law and order, he had no incentive to cease this behavior on the national level after his presidential election. However, the international community and pressure for domestic reform can aid in reestablishing human rights in the country.\nThe June 2020 UN High Commissioner’s Report called for an immediate investigation into the Philippine government. Nonetheless, considering the Philippines’ history of fronting investigations and surveillance of its security forces, it is possible that a domestic inquiry could suffer from internal corruption. It is essential for the United Nations, with the backing of hegemonic state actors and human rights advocacy groups, to pressure the Philippines into reform.\nThe Inter-Agency Committee must be replaced with an independent and transparent body that includes the review of human rights violations in drug-related crimes. The reformed committee needs to have the power to look into all wrongful death complaints and assure fair trials in their regard. For this to happen, there must be reform in the Philippines’ legal and policing systems to bring it in compliance with the international human rights regime.\nThe UN High commissioner’s report emphasized that “under international human rights law, the Philippines is obliged to establish rules and procedures for mandatory reporting, review, and investigation of lethal and other life-threatening incidents by law enforcement personnel.” The Philippines cannot be expected to present this reform on their own. Instead, the international community will need to pressure the state through non-violent means of naming and shaming and possible trade sanctions until the Philippines complies.\nThe right to life and a fair trial are universal human rights, that when undermined, threaten the foundations of democracy and peace. As a collective species, we cannot allow these rights to remain unheard of in the Philippines. It is the responsibility of those in positions of authority to protect individuals without a voice. Thus, the lack of the Philippines’ government to accept such responsibilities does not remove the problem but shifts the burden to those that can cause change, such as the global public and international community.", "pred_label": "__label__POS", "pred_score_pos": 0.5744885206222534} +{"content": "A common consequence of large urban construction sites is the increase in heavy vehicle traffic. As part of construction traffic management planning, engineers tend to choose the most direct route to the constructions site. However, the most direct route may not be the safest route, especially for Vulnerable Road Users (VRUs) such as pedestrians and cyclists. There is no recommended process for selecting a suitable truck route. Route planners may refer to the B-Double gazetted network maps, but these do not always reflect the current suitability of the road for heavy vehicles, nor does it reflect the surrounding land uses. As part of a wider VRU safety taskforce, the Heavy Vehicle Route Selection Working Group have developed the Human Impact Route Assessment (HIRA) tool and process to better capture the suitability of heavy vehicle routes with regards to VRUs.", "pred_label": "__label__POS", "pred_score_pos": 0.9352273344993591} +{"content": "Digging roots is easier with AI\nPublikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt\nThe scale of root quantification in research is often limited by the time required for sampling, measurement and processing samples. Recent developments in Convolutional Neural Networks (CNN) have made faster and more accurate plant image analysis possible which may significantly reduce the time required for root measurement, but challenges remain in making these methods accessible to researchers without an in-depth knowledge of Machine Learning. We analyzed root images acquired from three destructive root samplings using the RootPainter CNN-software that features an interface for corrective annotation for easier use. Root scans with and without non-root debris were used to test if training a model, i.e., learning from labeled examples, can effectively exclude the debris by comparing the end-results with measurements from clean images. Root images acquired from soil profile walls and the cross-section of soil cores were also used for training and the derived measurements were compared with manual measurements. After 200 minutes of training on each dataset, significant relationships between manual measurements and RootPainter-derived data were noted for monolith (R\n2=0.99), profile wall (R 2=0.76) and core-break (R 2=0.57). The rooting density derived from images with debris was not significantly different from that derived from clean images after processing with RootPainter. Rooting density was also successfully calculated from both profile wall and soil core images, and in each case the gradient of root density with depth was not significantly different from manual counts. Differences in root-length density (RLD: cm cm -3) between crops with contrasting root systems were captured using automatic segmentation at soil profiles with high RLD (1 to 5 cm cm -3) as well as at low RLD (0.1 to 0.3 cm cm -3). Our results demonstrate that the proposed approach using CNN can lead to substantial reductions in root sample processing workloads, increasing the potential scale of future root investigations.\nOriginalsprog Engelsk Tidsskrift Journal of Experimental Botany Vol/bind 72 Udgave nummer 13 Sider (fra-til) 4680-4690 ISSN 0022-0957 DOI Status Udgivet - 2021\nID: 260679429", "pred_label": "__label__POS", "pred_score_pos": 0.9897837042808533} +{"content": "Certain laws relating to self-defense were created known as \"Stand Your Ground\" laws. The public has interpreted these laws in ways that expand them beyond their original scope. To gain an understanding of self-defense laws, a look at the origins of self-defense is needed. Following the historical background, several cases will be examined that illustrate how the public has interpreted \"Stand Your Ground\" laws, and how these interpretations clash with elements of self-defense. Several philosophical principles including natural rights, the social contract, and some form of utilitarianism, will be discussed in relation to \"Stand Your Ground\" laws. A possible conclusion can be drawn that by misinterpreting \"Stand Your Ground\" laws, people compromise the philosophical ideals they hold, and infringe on other people's natural rights, break the social contract, and create societal unhappiness. Finally, some people are calling for reform of \"Stand Your Ground\" laws. These reforms focus on correcting public perception of \"Stand Your Ground\" laws.\nContributors\nCreated\n2013-05", "pred_label": "__label__POS", "pred_score_pos": 0.8435460925102234} +{"content": "Leisure and Recreation in America\nAdults typically lead structured play by providing supervision and a specified task for people to master a new skill. Typically, structured play is a physical or mental exercise (Tapps & Wells, 2018). It should not be too official or well-organized. It’s frequently a Playgroup activity with a defined goal and adult involvement, such as a preschooler-friendly game, a complicated puzzle, or the development of a Playgroup garden.\nDuring structured play, youngsters are acquainted with groundbreaking thoughts and openings, improving their turn of events and learning capacities, like setting the establishments for figuring out how to center, focus, alternate, and adhere to guidelines. (In need this answer in full or a new one? Please fill the form below or send a message/order ; Code\n0007).", "pred_label": "__label__POS", "pred_score_pos": 0.8130567669868469} +{"content": "WASHINGTON — Millions of retirees on Social Security will get a 5.9% boost in benefits for 2022.\nAs the economy struggles to overcome the effects of the coronavirus pandemic, the largest cost-of-living adjustment in 39 years is the result of a surge in inflation.\nAccording to Wednesday’s estimates by the Social Security Administration, the COLA increase is $92 per month for an average retiree.\nThe increase has a significant impact on household budgets for approximately 1/5 Americans, which is close to 70 million people. This includes Social Security recipients and disabled veterans, as well as federal retirees.\nThe policymakers claim it is a safeguard against losing purchasing power, not a pay increase for retirees.\n.", "pred_label": "__label__POS", "pred_score_pos": 0.787269115447998} +{"content": "MONFP: Clustering High-Dimensional Landmark-Based Two-Dimensional Shape Data\nAn important goal in image analysis is to cluster and recognize objects of interest according to the shapes of their boundaries. Clustering such objects faces at least four major challenges including a curved shape space, a high-dimensional feature space, a complex spatial correlation structure, and shape variation associated with some covariates (e.g., age or gender). The aim of this article is to develop a penalized model-based clustering framework to cluster landmark-based planar shape data, while explicitly addressing these challenges. Specifically, a mixture of offset-normal shape factor analyzers (MOSFA) is proposed with mixing proportions defined through a regression model (e.g., logistic) and an offset-normal shape distribution in each component for data in the curved shape space. A latent factor analysis model is introduced to explicitly model the complex spatial correlation. A penalized likelihood approach with both adaptive pairwise fused Lasso penalty function and L2 penalty function is used to automatically realize variable selection via thresholding and deliver a sparse solution. Our real data analysis has confirmed the excellent finite-sample performance of MOSFA in revealing meaningful clusters in the corpus callosum shape data obtained from the Attention Deficit Hyperactivity Disorder-200 (ADHD-200) study. Supplementary materials for this article are available online.\nCitation: Huang, C., Styner, M., and Zhu, H. T.. Clustering High-Dimensional Landmark-Based Two-Dimensional Shape Data. Journal of the American Statistical Association, 110, 946-961, 2015.", "pred_label": "__label__POS", "pred_score_pos": 0.6657655239105225} +{"content": "Experts agree that children thrive when their parents share the responsibility of raising them. Children themselves often express a desire to have both parents involved in their lives.\nUnder state law, mothers and fathers are to be treated the same in matters involving their children, regardless of any long-ago bias toward mothers. If someone is challenging your rights as a father, an experienced Simi Valley fathers’ rights lawyer could help you. Our firm’s reputable family law attorneys are committed to advocating on your behalf and preserving your right to a relationship with your children.\nAn attorney experienced in family law could diligently represent a father in matters, including:\nA father could face complicated legal challenges that threaten his time with his children in any of these cases. Seeking advice from a seasoned lawyer in Simi Valley regarding a father’s rights to be actively involved in his children’s lives could be critical.\nUnless a father has formally established the paternity of his child, he has no legal right to custody or visitation. Under California Family Code §7611, paternity is automatically presumed if the child was born to a married couple, or if the parents were unmarried but lived together as a family, and the man acted as a father to the child.\nIf no presumption exists, a father must seek a formal declaration of paternity before he can assert his rights to his child, which requires he or his legal representation to file a petition in Simi Valley family court and present evidence to a judge.\nA child’s legal father has the right to seek custody to develop and maintain a stable and loving relationship with his child. In many custody cases, a judge awards primary custody to one parent and visitation to the other. State law mandates that courts treat fathers as equally capable caregivers and award them primary custody if it is in the child’s best interests.\nIn cases where the father is not granted primary custody, he is entitled to seek court-ordered parenting time and visitation with his child on a set schedule. If the other parent interferes with that time, the father can seek contempt of court charges against them or a modification of custody. A dedicated attorney in Simi Valley could further explain a father’s legal options if anyone threatens his right to time with his child.\nWhen a judge awards a father primary custody of his child, the father has the right to seek child support from the mother. The amount the mother must pay is determined by the state’s mandatory child support guidelines. A father is entitled to use the same child support calculator as a mother, and a skilled lawyer could work with him to ensure he receives a fair and reasonable support amount.\nIf you are facing a legal matter involving your child, you may feel that you are being treated unfairly. This can be frustrating and upsetting when all you want is to provide your child a safe and loving home.\nContact a seasoned Simi Valley fathers’ rights lawyer today if you risk losing time with your child for any reason or have questions about paternity or child support. Our caring attorneys understand the struggle you face and can help you demonstrate to a court that you are a capable parent.\nHoffer Family Law Firm", "pred_label": "__label__POS", "pred_score_pos": 0.9485563039779663} +{"content": "A conversation with Dr. Vivian Balakrishnan, Minister for Foreign Affairs of Singapore, on how this city-state has tackled the coronavirus.\nFaced with the COVID-19 outbreak, governments have needed to act swiftly to combat the virus. Many countries currently have lockdown or measures alike in place. Yet, different countries approach the crisis in a noticeably different way.\nDr. Vivian Balakrishnan, Minister for Foreign Affairs of the Republic of Singapore, join this live podcast recording and explain Singapore’s approach and the various measures taken in dealing with the COVID-19 pandemic.\nInsights, debates, and research-based discussions on economic policy in Europe and beyond. The podcast is produced by Bruegel (https://www.bruegel.org/), an independent and non-doctrinal think tank based in Brussels. It seeks to contribute to European and global economic policy-making through open, fact-based, and policy-relevant research, analysis, and debate. A podcast member of EuroPod.", "pred_label": "__label__POS", "pred_score_pos": 0.7982676029205322} +{"content": "INTRODUCTION\nThe pipe, a small, handheld device used to smoke cannabis, is one of the oldest and most common smoking methods in the world. Pipes remain popular cannabis smoking devices today, largely due to their availability, affordability, ease of use, and wide range of types, colors, and styles.\nPart of using a pipe, bong, dab rig — or virtually any other smoking device — is knowing how to clean it. With frequent use, and without regular cleaning, pipes will build up residue that leads to clogging and affects smoke flavor negatively. For an optimal smoking experience, it’s important to clean your pipe regularly. Below is a step-by-step guide to cleaning and maintaining a pipe for optimal performance, smoke purity, and longevity of use.", "pred_label": "__label__POS", "pred_score_pos": 0.9502767324447632} +{"content": "514 Views | 1,155 Downloads\nAuthor Notes:\nCorrespondence Electronic address: pks6@cdc.goc\nWe thank the clinicians and administrations of the Shri Krishna Medical College Hospital and theKrishnadevi Deviprasad Kejriwal Maternity Hospital for their collaboration and support of this investigation, and their dedicated care of affected patients.\nWe are particularly grateful for the support of the pediatricians.\nWe also thank the JE/AES Program of the National Vector Borne Disease Control Program and the office of the Directorate General of Health Services for their support.\nWe are deeply indebted to the patients and their families for their participation and cooperation.\n[For a full list of contributions, please refer to the final publication.]\nWe declare no competing interests.\nSubject: Research Funding:\nUS Centers for Disease Control and Preventions\nThis study was supported by a CDC Research Project Cooperative Agreement Grant numbers GH-10-002 U2G GH000066-01-05.\nKeywords: global health neurology pediatrics encephalopathy", "pred_label": "__label__POS", "pred_score_pos": 0.8068245649337769} +{"content": "The Biden administration has announced details regarding two major legislative initiatives, and it’s important to stay informed on how these initiatives could affect you. The tax proposals would impact individual, corporate, and international taxes. A challenging legislative process is expected as Congress deliberates these proposals.\nStay informed with updates from our team of tax experts as we help guide you through this complex environment.", "pred_label": "__label__POS", "pred_score_pos": 1.0000096559524536} +{"content": "In September, Bangladesh’s apparel export earned a record $3.42 billion, with a growth rate of 41.66%, according to the data published by Export Promotion Bureau (EPB).\nBangladesh’s top apparel body, Bangladesh Garment Manufacturers and Exporters Association (BGMEA) and Bangladesh Knitwear Manufacturers & Exporters Association, (BKMEA) agreed that this is the highest growth in the apparel industry’s history.\nAlso, in the July-September period in the fiscal year, readymade garment (RMG) exported $9.05 billion garment items, registering an 11.48% year-on-year growth. Which was $8.12 billion in the last FY.\nAmong the total RMG export, $5.16 billion came from knitwear export. With 15.69% year-on-year growth.\nWhile, woven export earned $3.89 billion in the three months to FY 2021, growing by 6.35% year-on-year rise, according to EPB data.\nAfter nearly one and a half years, the woven sector registered a durable positive growth with the reviving of the global economies, especially in the western world.\nThe USA and the European Union (EU) have returned to normal with a large number of people being vaccinated against COVID-19. So the buyers of those countries are placing more orders for the coming summer and spring season just like before the pandemic.\nApart from that, some purchases were shifted to Bangladesh due to the military rule in Myanmar and the horrors of COVID-19 in India.\nEven before that, European and USA fashion buyers transferred some purchases from China to other countries including Bangladesh.\nThere have also been some purchases due to the long-term lockdown in Vietnam. All in all, compared to 2019, 15 to 20 percent more purchases have come.\nSeveral RMG leaders opined that many orders from the month of August were exported in September due to the container- crisis. That is why there is a big jump in apparel exports.\nThey are also optimistic that in October, 20% more work orders will come in the knit sector.\nHowever, due to the volatility of yarn prices, exporters are not very relieved.\nThe recent power crisis in China for several days will hurt the woven sector. As 80 percent of the woven fabric comes from China. While local entrepreneurs are sitting with the purchase order. If it is not solved on time, there will be a disturbance in exports rhythm.\nHome textile export earned $0.27 billion in the July-September period. Which witnessed a 10.65% jump compared to the same period last FY.\nSpecialized textiles export earned $0.038 billion in the July-September period. Grew by 29.08% compared to the same period last FY.\nAmong the specialized textiles export earnings, terry towel export earned 0.012 billion in the July-September period. Grew by 35.59% compared to the same period last FY.\nWhile special woven earned $0.007 billion in the July-September period. Grew by 35.71%% compared to the same period last FY.\nManmade filaments and staple fibers export earned $0.029 billion in the July-September period. Witnessing an 11.76% decline.\nIn the July-September period Jute and jute goods export earned $0.212 billion. Declining by 30.97%.", "pred_label": "__label__POS", "pred_score_pos": 0.5104718804359436} +{"content": "I will be presenting about “Food sustainability: changing trends, benchmarking and the latest solutions” at the World Green Economy Summit, programmed by Economist Impact Events, on October 6th.\nMy presentation will focus on the Food Sustainability Index (FSI), developed by Economist Impact with the Barilla Foundation.\nRegister here.\nSession description\nOur global food systems are being challenged like never before. Not only are they being tasked with supplying a growing global population with healthy, sufficient food to feed our families, but they must do so within the finite boundaries of the natural resources on which we rely.\nThe FSI is designed to track countries’ progress towards this formidable goal. It examines how food systems are performing across three pillars: food loss and waste, sustainable agriculture, and nutritional challenges. In the most recent report, the Economist analyses the G20’s performance on these pillars and investigates the opportunities for them to drive change on food sustainability.\nThis data-driven presentation will highlight and compare the performance of key countries and outline novel solutions to the rising food sustainability problem including: plant based proteins, sustainable aquaculture and the role of youth in leading food sustainability.", "pred_label": "__label__POS", "pred_score_pos": 0.9029493927955627} +{"content": "A guide to Google Analytics 4\nGoogle Analytics 4 (GA4) was officially launched in October 2020 and is the latest tracking and reporting platform by Google. It is reported to have been in development since 2017 when Google launched their “Google Analytics for Firebase”. However, a beta version was officially released in 2019 under the name “App + Web Properties.”\nGA4 is built using the Firebase Analytics backend and aims to make it easier to track both mobile and web properties under one platform. Since Google’s technology acquisition and eventual launch of the original Urchin tracker in 2005, it has rolled out three subsequent iterations of its tracking platform.\nGoogle has stated the following with regards to GA4’s purpose: GA4 can measure, unify and de-duplicate user interaction data, helping businesses and digital marketers to understand the user journey. It adapts to a changing environment as it relates to privacy. It reveals intelligent business insights by using machine learning. It can help to act more effectively on your data to achieve goals. So, what are the primary differences between universal analytics (GA3) and GA4? Measurement Model\nGA3 uses a model based on page views and sessions, while GA4 uses events and related parameters. Activities carried out by the user will generate an event (either using the auto tracked events or custom events). TRACKING GA4 has been designed from the ground up to track users over a range of different device journeys. GDPR and other worldwide data privacy laws are continually developing and have changed how our information is collected and processed online.\nWith the change in privacy laws, cookies add a layer of complexity for data processors to manage within their policies. As a result, GA4 is designed to collect data when available via cookies or simulate metrics using advanced machine learning techniques. Also, by moving the focus away from user-specific data to more behavioural-based metrics, GA4 is repositioning itself, with many new features and functions designed to enhance the study of on-site behaviours. Google is making its move in response to GDPR and other worldwide privacy policies with additional tools within GA4 for managing user data and the deletion of user information.\nViews\nGA3 offers a maximum of 25 views per property. Each view could have its own filters and goals if you wished – best practice suggests creating at least three for filtered, unfiltered and testing data sets. GA4 has only one view currently, although multiple DataStreams have some similarities.\nEvents\nLooking at GA4’s history, we can see its origins firmly based in the mobile application paradigm, where many old GA3 metrics are no longer applicable, and customisable events offer more flexibility.\nEvent types include: Automatically Collected– these are automatically logged and include language, page_location, page_referrer, page_title, screen_resolution. This is a significant departure from GA3 and a core attribute of the GA4 data model, where all user activity can potentially be converted to an event. Enhanced Measurement– these are additional events that can be enabled or disabled via the GA4 interface. Events include file_ download, scroll and video_start. Recommended Events– these are events with predefined names and parameters. Google recommends that you follow the suggested naming conventions where possible, but still offers you the ability to totally control how these events are fired using custom code (GTM etc). Custom Events– these are events that you name and implement yourself (similar to GA3). These events will require custom code to fire.\nIn GA3, an event is a special kind of hit (distinct from, for example, a pageview) that has a Category, Action and Label. By contrast, GA4 events have no Category, Action and Label but an event name and associated parameters.\nFollow the below steps if you want to translate a GA3 event to GA4: First, look for a matching automatically-collected event. If you find a matching event, you should not recreate a new event. If no matching automatically-collected event exists, proceed to step 2. Look for a matching Enhanced Measurement event. If you find a matching event, you should not recreate a new event. Look for a matching recommended event. Implement your tagging to trigger the recommended event using the naming convention suggested by Google. Finally, if you cannot find a suitable equivalent event, create your own custom event.\nThe new debug feature is a great help when testing events, but new event parameters and custom events may take up to 24 hours to appear in the reporting platform.\nIt should be noted that while the GA4 event management offers a large amount of flexibility, the lack of automatically collected event varieties and the ability to totally customise events could create a rather confusing outlook for agencies and users as they attempt to replicate the familiar GA3 metrics. This is probably one of GA4’s greatest strengths and weaknesses.\nGoals\nAnother significant change is the conversion measurement feature of GA4. In GA3, conversions occurred when a Goal was fired via a set of rules (for example, a landing page or event). You had a maximum of 20 potential goal place holders. GA4 no longer utilises goals as such, but you can switch any event over to a conversion.\nReports\nGA4 offers a much smaller range of individual reports compared to GA3. The intention of increasing the focus on the most important information. It no longer has a “Customisation” section that previously housed dashboards, saved reports and custom reports. The following report types are available in the GA4 Analysis Hub:\nExploration:allows you to create reports using tables, donut charts, line charts, scatter charts and geographic maps. Segment Overlap:create and select multiple audience segments to compare them and see where there are overlaps. Funnel Analysis:create ad-hoc funnel visualisations. ‘Standard Funnel’, which shows how users are completing steps or a ‘Trended Funnel’, which allows you to see trends for each funnel step. You can also ‘Make Open Funnel’, which will include people entering the funnel at any step. Path Analysis:how people travel through your website and app with a tree graph. User Explorer:drill-down to view individual user actions and segment your users. Cohort Analysis:group users based on the dates they visited your website or used your app. User Lifetime:provides access to metrics that include all available data for your users. For example, you can use the report to see the total value generated by your users. While the custom dashboard feature has now been removed, GA4 includes many pre-configured reporting dashboards, these include: Home:provides a top-level overview of your users and includes automated insights for the data generated by Google’s machine learning system. Realtime:lets you view current user activity on your website or app, including the number of users in the last 30 minutes. Acquisition:these reports show you how people are finding your website or app. For example, you can see the source and medium used to find your website. Engagement:lets you report on the pages people view on your website. The reports also include new metrics, like ‘Engaged Sessions’ which let you understand if people view more than one page or spend more than 10 seconds on your website. Monetization:shows revenue if you sell items on your website, accept payments in your app, or monetise your content with ads. Retention:provides cohort reports for your users, allowing you to see how often people return and engage with your website or app. Demographics:these reports let you view the geographic location of your users, along with other demographic information like age, gender and interests. Technology:lets you view details about the different devices people are using. If you’re tracking a website and an app, then you can also see a breakdown based on the platforms you’re measuring. All events:provides a list of all the events that have been tracked. Should you switch over to GA4?\nYes, partially. We would certainly recommend adding GA4 tracking to your existing site or new site, but we would also strongly suggest you do not stop using GA3. GA4 is still in its infancy, and Google will be adding more features as time goes on. The ecommerce tracking facilities are still not as sophisticated as GA3’s enhanced ecommerce, and third-party plugins and tools have a while to catch up with the service. Reporting, while sophisticated, can be a challenge due to its stripped-back nature. In fact, GA4 is a very stripped back service, with Google removing many of the metrics marketers have used for over a decade, probably preparing for a future with a much stronger emphasis on user privacy.\nAdding the GA4 code now will build up a history of analytics data that will be useful when you feel that GA4 offers a better solution to your analytics requirements.\nNote that while Google now defaults to GA4 in any new Analytics account setups, it is easy to create a property with both GA4 and GA3, or just GA3 if you prefer. How long this feature will be available is currently unknown.", "pred_label": "__label__POS", "pred_score_pos": 0.6869523525238037} +{"content": "Targeted radionuclide therapy of somatostatin receptor (SST)-expressing tumors is only partially addressed by the established somatostatin analogs having an affinity for the SST subtype 2 (SST2). Aiming to target a broader spectrum of tumors, we evaluated the bis-iodo-substituted somatostatin analog ST8950 ((4-amino-3-iodo)-d-Phe-c[Cys-(3-iodo)-Tyr-d-Trp-Lys-Val-Cys]-Thr-NH2), having subnanomolar affinity for SST2 and SST5, labeled with [177Lu]Lu3+ via the chelator DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid). Human Embryonic Kidney (HEK) cells stably transfected with the human SST2 (HEK-SST2) and SST5 (HEK-SST5) were used for in vitro and in vivo evaluation on a dual SST2- and SST5-expressing xenografted mouse model. natLu-DOTA-ST8950 showed nanomolar affinity for both subtypes (IC50 (95% confidence interval): 0.37 (0.22-0.65) nM for SST2 and 3.4 (2.3-5.2) for SST5). The biodistribution of [177Lu]Lu-DOTA-ST8950 was influenced by the injected mass, with 100 pmol demonstrating lower background activity than 10 pmol. [177Lu]Lu-DOTA-ST8950 reached its maximal uptake on SST2- and SST5-tumors at 1 h p.i. (14.17 ± 1.78 and 1.78 ± 0.35%IA/g, respectively), remaining unchanged 4 h p.i., with a mean residence time of 8.6 and 0.79 h, respectively. Overall, [177Lu]Lu-DOTA-ST8950 targets SST2-, SST5-expressing tumors in vivo to a lower extent, and has an effective dose similar to clinically used radiolabeled somatostatin analogs. Its main drawbacks are the low uptake in SST5-tumors and the persistent kidney uptake.\nRosalba Mansi, Guillaume Pierre Nicolas, Luigi Del Pozzo, Karim Alexandre Abid, Eric Grouzmann, Melpomeni Fani.Evaluation of a New 177Lu-Labeled Somatostatin Analog for the Treatment of Tumors Expressing Somatostatin Receptor Subtypes 2 and 5.\nMolecules (Basel, Switzerland).2020 Sep 11;25(18)\nPMID:\n32932783", "pred_label": "__label__POS", "pred_score_pos": 0.621714174747467} +{"content": "Posted on October 10, 2021 at 4:55 PM\nThe automotive sector has rapidly evolved, and new technologies are bringing in more efficiency and user-friendliness. The most popular innovation in this sector is electric vehicles that have become highly popular due to the debate that they are more environmentally friendly compared to fuel-powered vehicles.\nHowever, one of the innovations that will make up the future of the automobile sector is technological-savvy vehicles that require zero or minimal human input. Despite some strides manufacturers have made in this sector, none is yet to perfect these designs. However, one thing is clear, autonomous vehicles and robotaxis will be unveiled soon, and the world’s shift towards the digital market has already created a market for these vehicles.\nAutonomous Vehicles are now a Reality\nGermany has announced that it will be launching a robotaxis soon, which is a major step towards vehicle advancements. The greatest advancement in this area is the announcement made by Hyundai stating that it has converted the loniq 5 into a taxi that does not require any drivers. The final version of this new vehicle is expected to hit the market in 2023.\nHowever, the main challenge with any new technology is that it is always susceptible to threat actors, who actively assess any vulnerabilities that can be exploited. The fear in developing these technology-savvy vehicles is that once they are introduced to the market, they will be prone to cyberattacks. This is the same case with flying cars if they will ever arrive.\nThe best thing about technology is that as soon as a problem is discovered, others are always looking for ways that these problems can be alleviated if they are ever discovered. To this end, some researchers have already figured out how cyberattacks on these vehicles can be prevented using the blockchain technologies behind Bitcoin and Ripple.\nBlockchain Technology to Prevent Hacks\nA recent publication on IEEE Transactions on Robotics that involved the research from the Massachusetts Institute of Technology (MIT) and the Polytechnic University of Madrid demonstrated that blockchain technology is the solution to the menace of cyberattacks on technological advancements.\nThe research stated that robotic systems could be highly susceptible to hacking attacks because if one piece of the system is hacked, it could harm the entire system. This incident could spell doom for the entire infrastructure, whose weaknesses will be even more pronounced, and it could create an entry position for ransomware attacks or terrorism.\nThe research paper states that a transaction-based communication system could help prevent these attacks from taking place. This would be made possible by the high level of encryption that comes from using these transaction systems. The theory behind this research paper further states that robots added to a single system would automatically detect when one of the other robots within that system has been hacked.\nThese robots will achieve this functionality by detecting inconsistencies between the original content in a block and the later versions of that content, which indicates that the recent update has been hacked. The researchers noted that this strategy had a high chance of working because blocks in the chain comprise basic information of that robotic system and the coded version of the previous block details known as the ‘hash.’\nIf a malicious actor alters the content in a block, the hash will change, which will change the block’s connection with the rest of the chain. This action will ensure the unaffected blocks are notified, and they will detach from the affected blocks.\nMoreover, the system can also keep a record of all the transactions, which makes it possible for developers to add more functionality to the robots. By recording the transactions, the developers can identify any weaknesses that are coming up in these systems and evolve them to meet any future challenges. Furthermore, keeping a record of all the transactions will ensure that these systems are protected from any future attacks.\nRobotic vehicles that require no human action are a concept many people are waiting for, but research has shown that it presents many challenges. Every new technology comes with new weaknesses, and these are easily exploited by threat actors. However, cybersecurity researchers are always looking for ways that they can solve challenges before they arrive.\nBlockchain technology could work on these vehicles and ensure that threat actors do not corrupt them. However, this is still a potential solution, given that new technologies could also sprout in the coming years. With the Hyundai robotaxis, driverless vehicle expected to launch in 2023, a new, more advanced technology could be in play to minimize the risk of such attacks happening.", "pred_label": "__label__POS", "pred_score_pos": 0.5274924635887146} +{"content": "The bloom measured 3.5 feet across—1.6 inches more than its predecessor.\nEarlier this month, a particular Rafflesia tuan-mudae, spotted in a forest near Lake Maninjau in Indonesia, became the largest flower in the world, measuring 3.5 feet across (1.6 inches more than the previously the record holder). This new bloom grew in the same exact spot as its predecessor, which could indicate that it's actually the same plant.\nPeople who have smelled Rafflesia tuan-mudae (commonly known as the \"stinking corpse lily\") describe it as emitting a stench similar to that of rotting meat.\nBut despite its gargantuan size and smell, the most interesting thing about Rafflesia is that it's also a parasitic plant. According to New Scientist, it doesn't have leaves, stems, or roots and hides \"away inside their host plant\". Rafflesia grows on Tetrastigma vines, which belong to a genus of plant related to grapes. Tetrastigma provides the food and water for Rafflesia to grow and thrive during it's short week of life.", "pred_label": "__label__POS", "pred_score_pos": 0.8810842633247375} +{"content": "This study investigated the stabilization efficiencies of using an aluminum-rich precursor to incorporate simulated cadmium-bearing waste sludge and evaluated the leaching performance of the product phase. Cadmium oxide and γ-alumina mixtures with various Cd/Al molar ratios were fired at 800-1000 °C for 3 h. Cadmium could be crystallochemically incorporated by γ-alumina into CdAl4O7 monoclinic phase and the reaction was strongly controlled by the treatment temperature. The crystal structure details of CdAl4O7 were solved and refined with the Rietveld refinement method. According to the structural refinement results, the stabilization efficiencies were quantified and expressed as a transformation ratio (TR) with optimized processing parameters. The preferred treatment temperature was found to be 950 °C for mixtures with a Cd/Al molar ratio of 1/4, as its TR value indicated the cadmium incorporation was nearly completed after a 3 h treatment scheme. Constant-pH leaching tests (CPLT) were conducted by comparing the leachability of the CdO and CdAl4O7 phases in a pH 4.0 environment. A remarkable reduction in cadmium leachability could be achieved via monoclinic CdAl4O7 structure formation to effectively stabilize hazardous cadmium in the waste stream. The CPLT and X-ray photoelectron spectroscopy (XPS) results suggested incongruent dissolution behavior during the leaching of the CdAl4O7 phase.", "pred_label": "__label__POS", "pred_score_pos": 0.972687304019928} +{"content": "Abstract\nBackground: Valid instruments of parenting practices related to children's physical activity (PA) are essential to understand how parents affect preschoolers' PA. This study developed and validated a questionnaire of PA-related parenting practices for Chinese-speaking parents of preschoolers in Hong Kong. Methods: Parents (n = 394) completed a questionnaire developed using fndings from formative qualitative research and literature searches. Test-retest reliability was determined on a subsample (n = 61). Factorial validity was assessed using confrmatory factor analysis. Subscale internal consistency was determined. Results: The scale of parenting practices encouraging PA comprised 2 latent factors: Modeling, structure and participatory engagement in PA (23 items), and Provision of appropriate places for child's PA (4 items). The scale of parenting practices discouraging PA scale encompassed 4 latent factors: Safety concern/overprotection (6 items), Psychological/behavioral control (5 items), Promoting inactivity (4 items), and Promoting screen time (2 items). Test-retest reliabilities were moderate to excellent (0.58 to 0.82), and internal subscale reliabilities were acceptable (0.63 to 0.89). Conclusion: We developed a theory-based questionnaire for assessing PA-related parenting practices among Chinese-speaking parents of Hong Kong preschoolers. While some items were context and culture specifc, many were similar to those previously found in other populations, indicating a degree of construct generalizability across cultures.\nScopus Subject Areas Orthopedics and Sports Medicine User-Defined Keywords Encouragement Exercise Role model Screen time Young children", "pred_label": "__label__POS", "pred_score_pos": 0.6173566579818726} +{"content": "Maxicareprovides SME owners with affordable, reliable, high-quality healthcare to invest in their employees' well-being. Healthy employees form a solid and thriving firm!\nMarvin Agustin explains why he only believes in Maxicare SME Healthcare Plans.\nStartups, micro, and small businesses have been impacted hard. Small businesses are struggling to survive, and employee illness is on the rise. Sick employees cost companies money.\nDespite this, some firms refuse to offer health insurance, fearing it will raise already exorbitant expenses.\nIf only businesses knew that there is a reliable, affordable healthcare plan tailored to the needs and budget of a small business, all employees would be covered!\nMaxicare SME Healthcare Plansare designed for entrepreneurs and their employees. On September 24, Maxicare unveiled its newest celebrity brand ambassador, Marvin Agustin, at a Facebook Live event for the press.\nDespite his businesses' decline, he offered Maxicare SME Healthcare Plans to all of his employees. Changes in the food scene, he said. To be safe, we must be aware of the COVID threat. It's up to the unang-unang to ensure everyone's safety. We can't operate if people get sick, even your personnel, and it's unsafe for customers.\"\nObtaining healthcare policies for his employees proved challenging for the serial entrepreneur. \"To be honest, before our partnership with Maxicare, I was a bit overcharged,\" Marvin admits. Although I am not familiar with Maxicare's SME programs, it is evident that they have made them more convenient and cost-effective. They made it available to the sarili, kumpanya, and employed. You don't have to worry about whether or not you'll be protected if you're nasakit.\"\nLike many other SMEs, Marvin believed there was no suitable healthcare plan for him. \"Ang HMO, ang mga ganitong plans, malaking kumpanya lang.\" Syempre Maxicare is a reliable company. So, if those adjectives aren't mine, I'm sorry! If you don't verify, you're risking a lot for your company's and your employees' sake.\"\nHe went on to remark that providing excellent healthcare keeps him and his employees healthy. It's also ideal for his many enterprises. \"With COVID, we could get sick at any time.\" Andaming naapektuhan sa ganitong problema. No sales, but renta, suppliers, and personnel wages. However, if you don't have Maxicare or an HMO, you'll have more problems. Thanks to Maxicare, I've learned a lot more. Now I'm more equipped to operate my business and thrive with my team, and my team and employees will be safe knowing Maxicare can help them if they need it.\"\nHis enterprises thrive when his people are in top form, proving that #GrowthBeginsWithCare!\nMaxicare has 33 years of experience, 1.6 million members and is accepted by over 1,000 hospitals and clinics nationwide. However, according to Milky Gallegos, Maxicare's Assistant Vice President of Consumer Marketing, SMEs perceive their healthcare insurance are pricey or an added expense due to their reputation. A recent study found that SMEs, specifically those who do not invest in HMOs, spend an average of P21,600 per employee per year on healthcare. This is in addition to payroll and other expenses like pautang (cash loans) when an employee or a family member is sick. Quite a sum!\"\nWith Maxicare's healthcare plans, SMEs will save money while receiving high-quality care. \"Maxicare SME healthcare plans\" are under P21,000, says Milky. Our options range from P4,600 to P6,000 per person per year based on your company's size. As a result, many SMEs are unaware of huge disparities in spending. Investing in Maxicare SME healthcare insurance not only provides outstanding healthcare for your employees but also protects your business from unexpected costs. Thus, it benefits both the employees and the organization.\nJennifer Haw, the Yummyverse Group's Operations Manager, was one of Marvin's guests. She expressed her pleasure and joy at having a Maxicare SME Healthcare Plan to protect her. \"Maxicare gives you peace of mind,\" she said. At least you know that Maxicare is a must-have for anyone who wants to get the most out of their life. And, regardless of employee count, I strongly advise you to contact for your family's sake, especially today. He says he tips his tao at Maxicare. Upon checking, she is not expensive at all. It is Marvin's most acceptable investment.\nMarvin chose the Maxicare SME Healthcare Plan for Jennifer, one of his many employees. However, depending on each SME's budget, there are numerous product options. Jen Limbaring, Maxicare's Assistant Vice President of Consumer Sales, says these plans cover pandemic-related illnesses. The possibilities Jen listed were:\nMaxicare Plus is an HMO for companies with 10 to 99 employees. It is a comprehensive HMO for small businesses with three to nine employees. Maxicare BusinessEssential is a low-cost package for enterprises with three to 99 employees that includes an Outpatient Care Program or an Outpatient Care + Confinement Care HMO.\nA year-long package for micro-businesses starts at Php 4,651 per employee. Small businesses with 10 to 19 employees pay as little as Php 6,260, while those with 20 to 99 employees pay as little as Php 5,301.\nLess expensive than the out-of-pocket payments incurred by SME owners to cover their employees' healthcare. Pre-pandemic SMEs spent an average of Php 18,700 per employee on healthcare, according to a recent Maxicare survey.\nThanks to Maxicare SME Healthcare Plans, SMEs no longer have to choose between profitability and employee health. Employers can now provide healthcare suited to their employees' needs and budgets. Choosing Maxicare is a great business idea, which is why #MarvinAgustinChoosesMaxicare.\nLearn more about Maxicare and the details of each Maxicare SME Healthcare plan by visiting https://www.maxicare.com.ph/healthcare-program-for-my-organization/ or calling (02) 7798-7770.", "pred_label": "__label__POS", "pred_score_pos": 0.9507479667663574} +{"content": "What is the Difference Between Dementia and Alzheimer's?\nDiseases and disorders that impact mental health can be incredibly stressful for the victim and their family. While many of these diseases are unavoidable or irreversible, learning more about specific diseases will help prepare you for the journey and offer insight into managing symptoms. In this article we answer the question, what is the difference between dementia and Alzheimer’s? We analyze and contrast their symptoms and treatments.\nEspecially when dealing with older populations, there are two terms that often come up: dementia and Alzheimer’s disease. Although these terms describe similar phenomena, they are not the same thing.\nUnderstanding the difference between dementia and Alzheimer’s is a crucial step towards learning how to handle the specific case at hand.\nWhat is Dementia?\nDementia is not a specific disease at all. Instead, it is an umbrella term that refers to any disease that involves significant mental decline. By “significant,” the mental decline is recognized as severe enough to interfere with daily life.\nAs someone ages, a little cognitive decline is expected. This is a normal part of aging. Dementia refers to a condition where mental decline is due to damage to brain cells and not simply getting older. You should not panic the first time you forget a special date or have a jeopardy answer on the tip of your tongue.\nThese incidences are more than simply forgetting someone’s birthday every once in a while. These cases involve things such as regularly forgetting where someone is or even who people are. This condition is not only devastating, but it can be dangerous when victims forget to lock their door or leave the stove on.\nThere are many different types of dementia out there, and an individual can suffer from one or more at the same time. While dementia and Alzheimer’s are not the same disease, Alzheimer’s is the leading cause of dementia. Experts speculate that 60% to 80% of dementia diagnoses are due to Alzheimer’s.\nWhat is Alzheimer’s?\nAlzheimer’s is a specific disease that results in dementia symptoms that only get worse as time goes on. In the early stages, the disease manifests as an inability to form new memories or take in new information.\nAdvanced symptoms are often more troubling. They include more severe symptoms such as confusion and behavioral problems. It’s a devastating condition that often impacts the personality and leaves sufferers frustrated with their situation.\nVictims have issues performing bodily functions in the final stages, such as complications swallowing, speaking, and intentional movement. Although much research is dedicated to investigating the mechanisms of Alzheimer’s and how to control it, it is currently incurable. Experts still consider it a disease that cannot be cured.\nHow Do You Tell the Difference Between Dementia and Alzheimer’s?\nDementia refers to a number of conditions resulting from brain deterioration. What separates Alzheimer’s from other forms of dementia is the specific type of brain damage occurring. There are two abnormal structure characteristic of Alzheimer’s disease – plaques and tangles.\nPlaques are protein fragment buildups of beta-amyloid that form between nerve cells. Tangles are another protein buildup. They’re “tangled” fibers of a specific protein called tau that forms within cells.\nThese structures are what researchers believe are responsible for symptoms. They kill nerve cells in the brain and do more damage as the disease progresses. While these structures appear in the brains of healthily aging individuals, those who have Alzheimer’s grow these structures in a particular way. Victims’ brains tend to have more of these structures, and they grow in a particular pattern.\nIn Alzheimer’s patients, the structures begin to form in the regions of the brain associated with learning and spread from there in a way that mirrors the progression of symptoms. For doctors to definitively know that someone is suffering from Alzheimer’s Disease, they need to look inside your brain. In other words, they do not know for sure until after an autopsy is conducted following a patient’s death.\nThis does not mean that physicians cannot try to diagnose Alzheimer’s before then. There are several biomarkers and tests that physicians conduct to determine the likelihood that someone is suffering from Alzheimer’s.\nIf a physician believes that a patient likely has Alzheimer’s, they may prescribe specific drugs to help with the memory symptoms or behavioral shifts. These include drugs like:\nCholinesterase inhibitors Memantine Antidepressants\nThe best thing loved ones can do is create a supportive environment for Alzheimer’s patients to feel safe and comfortable.\nIf you believe you or a loved one is suffering from cognitive decline, get in touch with a physician immediately for expert advice.", "pred_label": "__label__POS", "pred_score_pos": 0.5088127851486206} +{"content": "In research, collecting data can be difficult, but fitting the data into a model that explains the observations is a challenge on another level. In neuroscience, many experiments measure the activity of neurons. However, to understand what exactly happens in a neuronal network, the data needs to be explained by a model. So, which model fits which data? A novel method developed by Pedro J. Gonçalves, Jan-Matthis Lueckmann, Michael Deistler, Jakob Macke and colleagues automates this process.\nTatjana Tchumatchenko has been awarded an ERC Starting Grant to investigate neural circuit function to gain new insights into neurological diseases like Huntington’s Disease. Tchumatchenko is Research Group Leader at the Max Planck Institute for Brain Research and a committed member of the Bernstein Network’s steering committee.", "pred_label": "__label__POS", "pred_score_pos": 0.9037594199180603} +{"content": "This project aims to aid the decision makers to identify the risky zones that are vulnerable to climatic changes, which in turn will impact the national development plans. This will help the decision makers plan appropriate actions in various sectors, and to acquire international financial resources for these plans. In addition to, it aims to develop an interactive application based on “Model Results” linked to geographic “Climatic Database” that is provided by the Intergovernmental Panel on Climate Change (IPCC) RCPs 4.5 and 8.5. This geographic application will include all historical climatic data and future projection data, related to Egypt.", "pred_label": "__label__POS", "pred_score_pos": 0.9948420524597168} +{"content": "Abstract\nThe origin of hotspot trails is controversial. Explanations range from deep mantle plumes rising from the core-mantle boundary (CMB) to shallow plate cracking. However, these mechanisms cannot explain uniquely the scattered hotspot trails distributed across a 2,000-km-wide swell in the sea floor of the southeast Atlantic Ocean. This swell projects down to one of the two largest and deepest distinct regions at the CMB, the Africa Low Shear Wave Velocity Province. Here we use 40 Ar/ 39 Ar isotopic analyses to date lava samples erupted at several hotspot trails across the Atlantic swell. We combine the eruption ages with an analysis of the structure and age of the sea floor, and find that the trails formed synchronously, in a pattern consistent with movement of the African Plate over plumes rising from the edge of the Africa Low Shear Wave Velocity Province. However, we also find that the seamounts initially formed only at the edge of the swell, where the oceanic crust was spreading apart. Later, about 44 million years ago, the hotspot trails began to cross the swell, but only in locations where the lithosphere was sufficiently young and thin that magma could reach the surface. We conclude that the distribution of hotspot trails in the southeast Atlantic Ocean is controlled by the interplay between deep-sourced mantle plumes and the motion and structure of the African Plate.", "pred_label": "__label__POS", "pred_score_pos": 0.5354810953140259} +{"content": "Gallery Room Born 29 May 1980, Gentry is a British graduate of Central St Martins in London. He has exhibited in galleries, museums and public settings in the UK, USA and Europe.\nAs part of a generation that grew up with floppy disks, VHS tapes, polaroids and cassettes, he is inspired by the impact of internet culture.\nObsolete Identities\nDrawing on recycled technological relics as the grounds for his portraits, Gentry creates a conversation between digital and analogue processes. Obsolete data formats are combined to form new identities, with a unique blend of personal information locked within.\nThese outdated objects are no longer in the spotlight, but we can use our understanding of the past to help us grasp the challenges of the future.\nTechnological Tipping Point\nThis has led to a study of how the natural world merges with technology. As we reach a tipping point, this new movement is becoming increasingly apparent as the key cultural and social transition of our time.\nWill humans be forever compatible with our own technology?\nEurope", "pred_label": "__label__POS", "pred_score_pos": 0.9946234226226807} +{"content": "Full text loading...\nWorld First: Drilling with Casing and Riserless Mud Recovery\nPublisher:European Association of Geoscientists & Engineers\nSource:Conference Proceedings, IPTC 2013: International Petroleum Technology Conference, Mar 2013, cp-350-00269 Abstract\nThis paper discusses the planning and operational aspects of drilling with casing (DWC) combined with riserless mud recovery (RMR), along with the benefits experienced compared to conventional drilling. The process of identifying and mitigating risk when applying new technologies to ensure a first time success will also be discussed. The Dampier Sub-Basin offshore Australia presents major challenges to tophole operations when drilling through the problematic ‘Bare Sands.’ The formation is composed of highly porous sand in which lost circulation is often encountered. Severe losses prevent sufficient hole cleaning, leading to packoffs around the bottomhole assembly (BHA) and stuck pipe. The formation is also interbedded with soft sand and hard cemented layers, causing severe torsional vibration and twistoffs in the BHA. Well designs and operations had been altered, incorporating larger hole sizes and control drilling to reduce packoff risks. Multiple bit runs were also optimised for each formation. This method reduced the occurrence of junked wells at the cost of individual well performance. DWC promised to enhance performance by drilling the interval in a single run and reducing the number of trips. However, as applications of new technology encompass risk and uncertainty, the operator performed extensive analysis to quantify the likelihood and cost of failure modes and the expected reward. A key finding of the analysis was a necessity to mitigate stuck pipe. RMR offered a cost-effective method of enhancing hole cleaning to avoid this hazard. The operation was performed from a semi-submersible rig, reaching a world record depth in technical limit time without hole condition problems. The methods discussed ensured the successful application of multiple new technologies, achieving a world record and technical limit performance. DWC combined with RMR is a world-first, and offers an effective solution for tophole drilling in the basin, and for similar basins worldwide.", "pred_label": "__label__POS", "pred_score_pos": 0.937720000743866} +{"content": "Non-essential travel to Belgium is prohibited for people who are not a national of the EU, nor of a country that is part of the Schengen Area, except for fully vaccinated individuals with a recognised vaccination certificate from 1 July 2021.\nTravellers under the age of 18 who arrive in Belgium from a country outside the European Union or Schengen Area will now be permitted entry regardless of their vaccination status, but they should be accompanied by another person who holds a valid vaccination certificate.\nAll incoming travelers to Belgium should fill in the Passenger Locator Form within 6 months of your scheduled arrival.\nVisitors from New Zealand are not required to present a negative COVID-19 PCR test or antigen result upon entering Belgium.\nChildren under the age of 12 and residents of Belgium are exempt from presenting a COVID-19 PCR-RT test result.\nFully vaccinated travelers with recognized proof of vaccination are also exempted from this requirement\nVisitors from New Zealand are not required to quarantine after entering Belgium.\nA 10-day quarantine is required, alongside a test requirement on the 1st and 7th days of quarantine.\nException applies to fully vaccinated travelers, negative covid test certificate holders, and those with a recovery certificate not older than 180days. They will be allowed a quarantine-free entry to Belgium.\nTravellers returning from Belgium must present a negative RT-PCR (NAAT) or Antigen (quick-test) test taken 72 hours before departure to New Zealand.\nExemptions apply to the following:\n1. Children who are under two years of age.\n2. Individuals who can present a medical certificate verifying they have been examined no earlier than 72 hours prior to departure and have been determined to be unable to undertake a test for medical reasons but do not exhibit symptoms of COVID-19\n3. Individuals with past (recovered) cases of COVID-19 who have a positive 72 hour or less test result, but have a medical certificate for showing that the individual is no longer considered by a medical practitioner to be infectious with COVID-19\nVisitors returning from Belgium will need to quarantine for 14 days upon entering New Zealand.\nTravelers to New Zealand from all countries, except eligible passengers from a quarantine-free travel zone (Niue and Cook Islands), must complete a 14-day stay in a managed isolation or quarantine facility.\nQuarantine-free travel for Australian passengers are temporary suspended until further notice.\nMost visitors from New Zealand can enter Belgium without restrictions.\nFully vaccinated visitors from New Zealand can enter Belgium without restrictions. Unvaccinated visitors from New Zealand can enter Belgium without restrictions.\nTravelers from New Zealand are not required to provide a negative COVID-19 test result.\nTravellers from New Zealand are not required to quarantine.\nMask usage in Belgium is not required\nRestaurants in Belgium are open. Bars in Belgium are open.\nFor press enquiries, corrections and any data-related questions, please email us at travel-restrictions@kayak.com.\nIf you're looking for personalised travel advice, like whether or not you should travel, please consult your local government’s resources (we won't be able to offer advice).", "pred_label": "__label__POS", "pred_score_pos": 0.8674529790878296} +{"content": "Use of Clinical and Laboratory Clue to Diagnose Anaerobic Infections in Limited Resource Setting Increase in life threatening infection despite the use of antimicrobial among patient’s in limited resource areas has made it imperative to investigate bacteria causing infections. However, comprehensive anaerobic bacteriology of clinical specimens is expensive and time consuming procedure. With advance in diagnostic techniques, the role of anaerobic bacteria in the etiology of various infection has become increasingly recognized. While a number of infections or intoxication due to anaerobic bacteria or their toxins arise from exogenous source such as the soil the majority are often endogenous origin arising frequently from the intestinal tract, oral cavity or the female genital tract. This chapter therefore highlight pointers for clinical and laboratory clue of anaerobic infection, additionally practical laboratory procedure to Isolate and identify anaerobes have been explained.", "pred_label": "__label__POS", "pred_score_pos": 0.9529667496681213} +{"content": "Proposed guidelines would help states shift away from stay-at-home orders.\nOn Monday, the Centers for Disease Control and Prevention released a draft of proposed guidelines for a phased reopening of some sectors in the American economy.\nTheir guidance for states, as they begin to lift stay-at-home orders and resume some operations, contains guidelines for child care centers, schools, day camps, faith-based institutions, bars and restaurants, and public transportation, and an outline of specific directions for each sector.\nThe guidelines note that “in communities that are deemed significant mitigation areas by State and local authorities, child care programs should be closed,” but that in other areas, programs can “choose to remain open to serve children of essential workers, such as healthcare workers.”\nThe CDC draft also proposes guidelines for “vulnerable workers” across all sectors and industries, encouraging workplaces to keep in mind that some workers are at higher risk for severe illness from COVID-19.\n“These vulnerable workers include individuals over age 65 and those with underlying medical conditions,” the guidelines state. “Such underlying conditions include, but are not limited to, chronic lung disease, moderate to severe asthma, hypertension, severe heart conditions, weakened immunity, severe obesity, diabetes, liver disease, and chronic kidney disease that requires dialysis. Vulnerable workers should be encouraged to self-identify, and employers should avoid making unnecessary medical inquiries.”\nThe draft is under review by White House officials, and the CDC could release a final proposal yet this week.\nAs the Lord Leads, Pray with Us… As the Lord Leads, Pray with Us… For officials with the CDC working on guidelines for various segments of the American economy. For those in the White House charged with reviewing the guidelines proposed by the CDC. About the need for balance between the nation’s physical and financial health. Sources: RECENT PRAYER UPDATES", "pred_label": "__label__POS", "pred_score_pos": 0.959067702293396} +{"content": "Using a student-centric approach rather than a business-centric one could benefit institutions: Opinion\nJuly 27, 2021\nPostsecondary institutions would benefit from using a student-centric approach rather than focusing on business models, writes Steve K Stoute. The author argues that postsecondary institutions have been under stress for some time, but that focusing on meeting the needs of students will have greater benefits. Stoute says that institutions should recruit the students that are best fitted to the institution using data and predictive analytics, and work to provide additional supports to student groups such as adult learners and historically underrepresented populations. Additionally, the author argues that institutions should empower students to own their academic experience and provide co- and extra-curricular experiences to enable holistic development.\nInside Higher Ed(Editorial)", "pred_label": "__label__POS", "pred_score_pos": 0.6226460933685303} +{"content": "Even before extremist group activity was exposed in Australia’s 2021 anti-lockdown demonstrations, there was growing concern about right-wing extremism in Australia.\nThe annual threat estimates from ASIO and the US note that right-wing extremism in Australia is on an upward trend. Ideological extremism now makes up 40% of the ASIO caseload.\nOur research at the University of Canberra’s National Security Hub is examining online influence operations targeting Australia, including its veteran community. This is a global problem and was one of several issues noted at this year’s International Terrorism and Social Media Conference in the UK.\nFor researchers like us who focus on the welfare of veterans – particularly during the aftermath of a military withdrawal from Afghanistan – such extremist groups present a complex and dangerous threat to the community.\ntransition to civilian life\nThe transition to civilian life can be a vulnerable time for many veterans. Suicide, homelessness and incarceration rates are alarmingly high for Australian veterans.\nSome veterans find that their ideological beliefs are tested during the transition to civilian life, when they feel most disconnected from the military community, which has so far played such a fundamental role in their sense of self.\nIt is during this period, and not during service, when ex-servicemen are particularly vulnerable to radicalisation.\nIn some cases, veterans have voiced being actively ostracized by their former allies for leaving the military. This has left him disillusioned with the entire institution.\nThis, unfortunately, may make these veterans more vulnerable to the appeal and influence by extremist groups, who are now offering companionship and camaraderie to the missing in their lives.\nSuch groups often promote a mission-based approach, which can attract people who lack the sense of purpose valued by them in military service.\nThere is a risk that this could lead well-meaning veterans to participate in groups whose ideals they generally considered questionable.\na widespread risk to the public\nThis is not a specific Australian issue.\nNearly one in five defendants served in the military in response to the January 6 US Capitol attack.\nViolence from participating in online forums to physically violent acts can happen rapidly and sometimes without obvious warning signs. The goal of these extremist groups is to gain a group of already trained members who can not only be activated immediately, but are also able to train others.\nPeople with military experience and training in warfare, weapons or explosives are a clear threat if radicalized by extremist groups. One study suggests that some veterans associate with such groups as trainers, rather than committing extremist acts themselves.\nThe newly established UK-based Veterans 4 Freedom (V4F) group also lists service in the military as a membership requirement.\nThe group claims to be about 200-strong and focuses on “anti-vaccine” crimes, such as organizing marches. However, in discussions on the group’s private Telegram account, it plans to step up its activities.\nMedia reports suggest that discussions on the forum also included an awareness that there are currently serving military members who may become “enemy fighters” as a result of V4F’s actions. Not only are these “freedom defenders” anticipating a confrontation, they are prepared to fight their former brothers and sisters to achieve their goals.\nVeterans in Anglo democracy are being targeted by open and covert online influence campaigns, using fake military profiles to connect and defraud defense contractors and current and former military members.\nVeterans are also ideal targets for international online influence operations that encourage the promotion of particular political candidates, parties or ideologies. Many of these operations start in Russia or China.\nduty of care\nSo, what duty does the Australian Defense Force have towards its members – and the community at large – to better prepare them for the threats they face as they transition to civilian life?\nOrganizations such as the Global Internet Forum to Counter Terrorism (a collaboration between the technology industry, government, civil society and academia) are actively engaged in monitoring and preventing violent extremist content and activity on online platforms.\nBut military members and their families will benefit from awareness and prevention programs designed specifically for the community – especially if offered.\nbefore this They transition into civilian life.\nAssistance should also be offered to assist and protect ex-servicemen wishing to leave such groups.\nWell-designed containment programs can help prevent recruitment by extremist groups in the hopes of leveraging military skills and knowledge, and can be offered as part of military evacuation processing.\nIf this article has raised problems for you, or if you are concerned about someone you know, call Lifeline on 13 11 14 or Open Arms on 1800 011 046 or the Open Arms website Go..", "pred_label": "__label__POS", "pred_score_pos": 0.5045367479324341} +{"content": "Driving without a license in Smyrna is not just another traffic violation. In Georgia, this offense could result in criminal misdemeanor penalties, including jail and probation, if you’re convicted.\nThe law requires every driver to have a driver’s license in their immediate possession when driving a vehicle. So, even if you have a valid license, you could still face penalties for driving with no license in Georgia if you do not have your license on you during a traffic stop.\nAn officer will also cite or arrest you if you refuse to comply. Refusing to hand over your driver’s license can make a bad situation worse. However, if you can prove that you had a valid license at the time of the traffic stop, you may be able to resolve your citation with a minimal fine.\nAnother common scenario for this offense is driving with a suspended license. This violation is more serious than misplacing the card, or forgetting a valid license at home. Even though some drivers may be unaware that that their license is suspended, they still face significant penalties. For this reason, it’s a good idea to check your current license status if you think there might be any issues.\nFinally, you may also receive a citation for this offense if your license has been canceled, revoked, or disqualified by the DDS.\nWhat Are the Consequences of Driving Without a License?\nPenalties for this traffic violation may vary based on the jurisdiction, driver’s age, and prior driving history.\nTypical consequences include a fine, two days in the county jail, and license suspension. But, the outcome can be more concerning for those who decide to fight the charges without an experienced Smyrna Traffic Lawyer by their side. The court often dishes out the maximum penalties in these cases.\nHowever, a skilled traffic violation lawyer can help improve your odds. They may be able to:\nIdentify areas in your case that would be a viable defense Get charges reduced Help you avoid an automatic suspension\nIf you’re serious about fighting a no license charge in Georgia, schedule a free consult with a traffic attorney before going to court.\nResolving a No License Charge at Smyrna Municipal Court\nIf an officer issued your citation within the city limits of Smyrna, Georgia, the government will likely schedule a court date at Smyrna Municipal Court. This court is responsible for processing all traffic citations and misdemeanor state law violations issued by the local police department.\nIf you plan to fight the no license citation, you can show up to your court date and plead not guilty. And, if you want to have your case heard before a jury, you can request a transfer to a higher court – Cobb County State Court – during your arraignment.\nBut, if you don’t plan to fight the charges, drivers can sometimes resolve traffic violations online by paying the ticket. The automated system will notify you when you attempt to pay if a court appearance is required.\nIf you have questions about your citation or court date, you can contact Smyrna Municipal Court at 770-431-2804.", "pred_label": "__label__POS", "pred_score_pos": 0.7369276285171509} +{"content": "Escalating costs may present an unexpected obstacle to the scheduled spring 2008 start of construction on the 23–mile extension of Washington, DC's Metrorail system to Dulles International Airport. According to a new report by the U.S. Department of Transportation's inspector general, the cost of project's 11.6–mile first phase––currently estimated at $2.7 billion––has nearly doubled since December 2004. The rise threatens to push the public–private project beyond cost–effectiveness criteria necessary to receive $900 million in federal funding under the Federal Transit Administration's New Starts program.\nThe extension is a collaboration of the Commonwealth of Virginia, the Metropolitan Washington Airports Authority, and Dulles Transit Partners (DTP), which co–owned by Bechtel Infrastructure, Inc. and Washington Group International. The report speculates that the cost increase may be due in part to a lack of competition for the design/build contract, which was awarded under a Virginia law that permits negotiations with a single bidder for large–scale transportation projects. In addition to the FTA grant, the extension is to be funded by a $375–million loan, revenue from the adjacent Dulles Toll Road, and other local sources.", "pred_label": "__label__POS", "pred_score_pos": 0.655221164226532} +{"content": "For example, DNA, RNA and protein sequence data is frequently well beyond the scope of traditional data analysis. Fortunately, big data analytical techniques can be used to gather highly precise insights from these data sets.\nFor example, machine learning technologies allow researchers to “train” artificial intelligence systems to analyze and group biological data in interesting and informative ways. This can potentially result in analyses that the researchers themselves would not have considered before. However, this process requires significant computing power, which would not be possible without a seamless and robust IT setup. Furthermore, it is often impractical to house such systems using on-premises hardware.\nTo help deliver better technology to research teams, cloud computing has been adopted as a major part of the bioinformatics ecosystem. Using the cloud, teams can access computing resources exactly when they need them with no restrictions on where they work (thus, labs can be established without needing to think about where to house all the necessary IT resources). Additionally, the cloud can help teams scale their experiments with minimal lead time. This results in better and faster outcomes from both a research and business perspective.", "pred_label": "__label__POS", "pred_score_pos": 0.9978199005126953} +{"content": "Featured Partnerships Midland College Dual Credit & Technology Education Programs\nDuring recent months, Dr. Steve Thomas, President of Midland College (MC) and representatives of the Midland Development Corporation (MDC) have engaged in intense planning sessions with the goal of increasing the number of students who complete college-level career and technology programs at MC. These programs, which lead to college certifications and associate degrees, prepare students to fill skilled technical positions in local businesses and industry. MC has established a five-year plan for expanding their technical education program. The transition to this new approach began in August 2017.\nEnrollment will increase significantly during the upcoming academic year, and should continue to increase until the academic year 2019-2020.\nAcademic Year Enrollment 2016-2017 301 2017-2018 (transition year) 520 2018-2019 690 2019-2020 730 2020-2021 730 2021-2022 730\nCurrently, MD provides classes to students at a reduced tuition rate. To achieve targeted growth, this practice must continue as the local school districts have not appropriated funds to pay for the tuition. However, this leaves MC without critical funding to pay for the expansion of programs. Furthermore, career and technical programming, largely provided at the Advanced Technology Center (ATC), is more expensive than traditional lecture-based instruction and requires special facilities and laboratories with updated equipment and supplies.\nFor the 2017-2018 transition year, MC must remodel and equip two new Energy Technology labs and upgrade equipment in existing Automotive Technology, Diesel Technology, and Health Sciences labs. Additionally, MC will need to upgrade technology throughout the ATC, and employ a minimum of three new faculty members to serve additional students. These faculty members must have direct industry experience in addition to academic credentials, and will be employed for extended annual contracts.\nAfter the 2017-2018 transition year, MC will need to expand and equip labs based on student progression into advanced coursework, and must maintain the existing equipment. Faculty needs will grow, as will the need for library and learning resources such as computer labs.\nIn developing the requirements for this program, MC and MDC have focused on continuing our commitment to career and technology education with flexibility and affordability which will allow students to succeed. We believe these new and expanded programs will appeal to students who already have a strong commitment to Midland and want to remain in the Permian Basin after graduation.\nTo provide the needed programming, the MDC has provided MC with a five-year commitment of $1.35 million. According to the contract, the MDC shall provide $250,000 annually for the first three years beginning in August 2017, and $300,000 annually for the fourth and fifth years of the contract.\nMidland, TX 79705", "pred_label": "__label__POS", "pred_score_pos": 0.9843977093696594} +{"content": "Written By Leah Smith, Summer Intern\nOur own Kathy Taylor graduated from the Leadership Fairfax Institute (LFI) this past weekend, having completed the 10 month program. LFI trains individuals to become more effective leaders, and to take initiative in their own communities. Participants are taught, using a continuous improvement model, to engage with others, brainstorm creative solutions, and identify and resolve issues facing the community. Study groups, training seminars, and interactions with community decision makers\nBy learning from and connecting with peers, program members deepen their leadership competencies, focus their leadership vision, and gain an in-depth knowledge about Fairfax county engagement. Others in our office who have completed this program include Lynne Strobel – now an LFI board member – and Bob Brant. Lynne affirms that “The Leadership Fairfax Institute provides a solid foundation to engage in those issues most critical to Fairfax County. I am proud to serve on its Board, and am delighted that Bob Brant, Class of 2019, and Kathy Taylor, Class of 2021, chose to complete the program. As a result of his experience in LFI, Bob now serves on the Board of Langley Residential Support Services.” The effects of the LFI program are pronounced as many graduates become community leaders. We are excited for Kathy and will be thrilled to witness the continuous benefits of the LFI program.", "pred_label": "__label__POS", "pred_score_pos": 0.532551109790802} +{"content": "Evaluation methodologies privilege RCTs for establishing whether treatments work. This makes it difficult to warrant more complex treatments, like psychological therapies, which are hard to test with RCTs. It also misses many outcomes that matter to service users beyond the easily targeted symptoms and it downgrades the role of clinical judgment. Working with EU data, and based on preliminary philosophical and methodological research already underway [Cartwright (forthcoming)], K4U will develop a credible framework alternative to RCTs for evidencing therapies.\nResource\nJeremy Clarke Biography (2016) (last modified: 6 February 2019)", "pred_label": "__label__POS", "pred_score_pos": 0.698671817779541} +{"content": "The pandemic has resulted in a steep rise in medical-aid claims. Covid-19 is after all a prescribed minimum benefit* (PMB), which means medical aids must cover the cost of treating members for it.\nBut it doesn’t mean you can claim for every Covid expense that arises – everything still must comply with the guidelines of your fund.\nHere are eight common questions about Covid-related expenses and how medical funds pay for them.", "pred_label": "__label__POS", "pred_score_pos": 0.9031410813331604} +{"content": "Volunteers for charities and other nonprofit entities have an additional line of defense against the threat of personal liability now that Congress has finally passed a federal Volunteer Protection Act. Acting in the euphoria for citizen service following the Presidents’ Volunteer Summit in Philadelphia in April 1997, Congress passed with fanfare a bill that had been languishing in both House and Senate, in various forms, for a decade.\nThe law (42 USCA Sec. 14501 et seq.) generally provides that volunteers will not be personally liable for their acts or omissions if they are acting within the scope of their responsibility for the organization and the harm is “not caused by willful or criminal misconduct, gross negligence, reckless misconduct, or a conscious, flagrant indifference to the rights or safety of the individual harmed.”", "pred_label": "__label__POS", "pred_score_pos": 0.6933948993682861} +{"content": "Choice has always been a finicky thing in games, and how developers have consistently used choice has trained gamers to react to it in a certain way.  That way is almost exclusively about weighing the costs of what you may get or lose.  We have, by and large, tied most choice in games to rewards, or lack thereof.\nBioshock, for instance, pretty much told you up front “If you play this way you’ll get a reward, and if you don’t, you won’t.” So you weren’t making a choice based on the story or your emotions, you were making it as a calculating gamer deciding which way was better.  Even if you thought you were making it emotionally, you likely weren’t, as you likely expected, even if subconsciously, to be rewarded for “picking right”.  And the game obliged; if you saved all the little sisters, you ultimately got a better reward for it in the end.\nAnd that’s the conundrum facing developers.  How do you make a player choose based on story and emotion instead of that cold calculating center that has been cultivated all these years?  We’ve been so conditioned to believe there is a good and bad ending, and good and bad solution, that it’s hard to imagine a situation where this won’t factor in.  We weigh every split in a path, and each door against the other, worried that we might miss out on some little treat hidden somewhere.\nEnter Mass Effect 2.  It is a sequel to a game where you made choices, and it will have a sequel where your choices are realized.  I saw the consequences of my decisions in the first game realized in Mass Effect 2.  And I knew beyond a doubt that my choices in ME2 would be realized in ME3.  But they offered no treats; I knew that whatever I decided would not be reflected in this game, and because of that, it shut down my gamer brain.  I was no longer searching for the best outcome.  I was no longer worried about missing out on something important.\nThis game made me do what no other game has:  I made decisions based on my feelings.  I was Shepard.  For the first time in 25+ years of playing video games, my decisions were based entirely on the raw emotional impact of the situation.  I couldn’t game the system.  I couldn’t know what would happen based on my decisions, except to evaluate it as a character in that universe.  All I knew was that my decisions will be important, and that, for once, I cared about the outcome, rather than the reward.\nI’m sorry Mordin.  I cannot condemn your actions concerning the Genophage, but neither can I assuage your guilt.  Your decision was a hard one, and while I understand it, I cannot condone it.\nRIP Legion.  I know we will meet again, but I still wish I’d chosen better.", "pred_label": "__label__POS", "pred_score_pos": 0.5284638404846191} +{"content": "The way forward to strengthened policies and practices for unaccompanied and separated children in Europe\nThis paper captures concrete recommendations for efficient, lean, and harmonised processes which ensure children are protected and can access procedures and solutions in accordance with their best interests. It is a result of a consultative process carried out by UNHCR, UNICEF and IRC with around 100 practitioners from nearly all European countries, a roundtable with nine European states, consultation with European Union (EU) level actors, and individual or group discussions with over 50 unaccompanied and separated children living in Europe.", "pred_label": "__label__POS", "pred_score_pos": 0.8122671842575073} +{"content": "dc.description.abstract Green Virtual Enterprise Breeding Environments (GVBEs) are long-term strategic alliances of greenenterprises and their related support institutions aimed at offering the necessary conditions (e.g. human,financial, social, infrastructural and organisational) to threefold support: (a) the evolution of their memberenterprises to become Green Enterprises, (b) the rapid and fluid configuration of dynamic Green VirtualEnterprises as forward and reverse supply networks, and (c) the sharing and recycling of resourcesby means of collaboration mechanisms such as: information, materials, water, energy and/or infrastructure(services) with the intention of achieving sustainable development in a collaborative way.This thesis aims to systematically demonstrate a toolkit development, outlining the necessary ‘ingredients’,or elements, for creating and managing a GVBE, where this GVBE achieves desirable systemic propertiesdefined by a synergy of principles drawn from the Industrial Ecology (IE), Collaborative NetworkedOrganisations (CNOs), Systems Theory (ST), and Enterprise Architecture (EA) disciplines. In doing so,it is hoped that the thesis will achieve the following goals: (A) The pragmatic goal of helping IE protagonistsand CNO managers to create feasible GVBEs, and (B) The goal of identifying missing ingredients/elements,those that are necessary but not-yet available.The proposed GVBE toolkit included the following main reference artefacts (or models) – supportingthe GVBE lifecycle management: A GVBE Reference Model characterizing the GVBE unique features and highlighting the synergeticopportunities between collaboration and sustainability practices. A GVBE Reference (Modelling) Framework with five building blocks: (1) targets, (2) actors,(3) operating principles, (3) lifecycles and (5) technologies (systems and tools) to create andmanage GVEs and their breeding environments. A GVBE Reference Maturity Model with six GVBEs Evolutionary Models (viz. (1) Standard VBE,(2) Eco-labelled GVBE, (3) Environmental GVBE, (4) Eco-Efficient GVBE, (5) IndustrialSymbiosis GVBE and (6) Eco-Industrial GVBE) and their Eco-Industrial Networking Strategies in10 domains (viz. materials; energy; transportation; marketing; human resources; I & C Systems;Environmental, Health and Safety; Production Processes; Quality of Life and Community; andWaste Management). A GVBE RESOLVE Strategies Reference Model with six circularity strategies: Restore/Regenerate,Sharing, Optimise, Loop, Virtualise, and Exchange. A GVBE Bag of Assets Reference Model with new suggested Circular and Sharing Economiesbusiness opportunities to be explored. A F-GVE Reference Model (dynamic forward supply network) with sustainable manufacturing,logistics and consumption strategies for offering and delivering green products to the market in asustainable way. A R-GVE Reference Model (dynamic reverse supply network) with closed-loop networks strategiesfor recovering the products sold under the GVBE brand (product stewardship) for direct-use, repair,re-manufacture, recycle or safe disposal. A GVE Broker Reference Model as a vital actor/role for the identification and/or developmentof new circular and sharing economies within the GVBE and green (collaboration) businessopportunities within the market/society. A GSVE Reference Model as an advanced GVE model enabled by the next generation technologiescorresponding to the Fourth Industrial Revolution or Industry 4.0.Finally, the GVBE toolkit was validated against the Sustainable Engineering principles, Circular Economyprinciples, Systems of Systems Engineering principles, and the Viable System Model sub-systems functionsrequirements to guarantee at ‘preliminary design level’ the viability and sustainability of a GVBE andits GVEs.", "pred_label": "__label__POS", "pred_score_pos": 0.8168665170669556} +{"content": "Validation of Oximetry for Diagnosing Obstructive Sleep Apnea in a Clinical Setting.利用統計を見る\nFile / Name\nLicense\nclockssleep2030027\nThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited\nA large epidemiological study using oximetry to analyze obstructive sleep apnea (OSA) and metabolic comorbidities was performed in Japan; however, reliability and validity of oximetry in the Japanese population remains poorly understood. In this study, oximetry data from the epidemiological study were compared with data from clinically performed polysomnography (PSG) and out-of-center sleep testing (OCST) in epidemiological study participants who later attended our outpatient units. The oxygen desaturation index (ODI) from oximetry showed a moderate positive relationship (correlation coefficient r = 0.561, p < 0.001) with apnea/hypopnea data from PSG/OCST. The area under the receiver operating characteristic curve showed moderate accuracy of this method in the detection of moderate-to-severe or severe OSA. However, the optimal ODI thresholds to detect moderate-to-severe OSA and severe OSA were the same (ODI > 20.1). Oximetry may be a useful tool for screening moderate-to-severe or severe sleep apnea. However, it may be difficult to set an appropriate threshold to distinguish between moderate and severe sleep apnea by oximetry alone.", "pred_label": "__label__POS", "pred_score_pos": 0.6853947639465332} +{"content": "Opiate-Induced Bowel Dysfunction Pharmacy Times, Volume 0,0\nOpiate-induced bowel dysfunctioncan pose a significant clinical problem.Jonathan Gonenne, MD, and colleaguesevaluated the effects of alvimopan,a peripheral mu-opioid antagonist,on codeine-induced delays ingastric, small bowel, and colonic transittime in healthy volunteers (43women, 31 men). In a double-blindedstudy, patients were randomized to 1of 4 groups: alvimopan 12 mg bid withor without codeine sulfate 30 mg 4times/day, codeine alone, or placeboalone. Gastric emptying and smallbowel and colonic transit were measuredby scintigraphy.\nPrimary end points for colonic transitwere geometric center (GC) of thecolonic counts at 24 hours and timefor 50% ascending colon emptying.Codeine delayed gastric, small bowel,proximal, and overall colonic transit(\nP < .05). Alvimopan reversed theeffect of codeine on small bowel andcolon (ascending colon and overallcolonic transit) and accelerated overallcolonic transit, compared withplacebo (GC 24 hours, P < .05). Alvimopandid not reverse the codeineinduceddelay of gastric emptying( Clinical Gastroenterology and Hepatology,August 2005).", "pred_label": "__label__POS", "pred_score_pos": 0.9138234853744507} +{"content": "Tax liability\nThe taxpayer is the recorded holder or owner of the car. If the register contains both an owner and a holder, it is the holder who is the primary taxpayer. The tax liability can also be determined based on a notification of transfer submitted to the register.\nTransfer of tax liability\nIt is possible to transfer the tax liability from the car’s first holder to its first owner. This transfer is applied for in writing by the car’s owner and comes into force no earlier than the following tax period.\nTax period\nThe tax period for vehicle tax is 12 months, and a new period always begins automatically when the previous one ends. The tax period is interrupted when the car is sold onwards, decommissioned, or permanently deregistered. Similarly, a new tax period begins when, for example, a car is registered or commissioned for road use.\nYou have to pay vehicle tax for the period when you are the vehicle owner or holder. Please note that for short tax periods\nthe minimum vehicle tax charge is 10 €.\nFor example, when carrying out a car sale, the seller is still liable for the vehicle tax for the date of sale, while the buyer is liable from the following day onwards. If the case involves a first-time registration or re-registration of a vehicle, the buyer is liable to pay the tax immediately from the date of registration.\nDo not pay the tax directly with the seller’s tax bill when you buy a used car. When you register the car in your name, you will receive a new tax bill. Check the car’s tax details before purchasing it. Overdue vehicle tax will incur a prohibition of use.", "pred_label": "__label__POS", "pred_score_pos": 0.6766475439071655} +{"content": "De Beers has announced it is leading a research project that aims to make some of its mines carbon neutral within five years. The idea involves storing carbon through the mineralisation of kimberlite waste from the diamond extraction process. This could potentially offset up to ten times the emissions of a typical mine.\nDespite positive steps to develop sustainable practices, the mining industry continues to suffer from a bad reputation. Whether it is the memory of large accidents in the past, or the environmental impact the industry can have on local communities, mining companies often struggle to obtain the social licence they need to operate.", "pred_label": "__label__POS", "pred_score_pos": 0.9901401400566101} +{"content": "Abstract\nA signal initiated by the newly formed Ag receptor is integrated with microenvironmcntal cues during T cell development to ensure positive selection of CD4\n+CD8 + progenitors into functionally mature CD4 + or CD8 + T lymphocytes. During this transition, a survival program is initiated, TCR gene recombination ceases, cells migrate into a new thymic microenvironment, the responsiveness of the Ag receptor is tuned, and the cells commit to a specific T lineage. To determine potential regulators of these processes, we used mRNA microarray analysis to compare gens expression changes in CD4 +CD8 + thymocytes from TCR transgenic mice that have received a TCR selection signal with those that had not received a signal. We found 129 genes with expression that changed significantly during positive selection, the majority of which were not previously appreciated. A large number of these changes were confirmed by real-time PCR or flow cytometry. We have combined our findings with gene changes reported in the literature to provide a comprehensive report of the genes regulated during positive selection, and we attempted to assign these genes to positive selection process categories.", "pred_label": "__label__POS", "pred_score_pos": 0.993304967880249} +{"content": "Elite and recreational athletes are emerging from a unique challenging time and this lecture and open discussion will address injuries and return to sports for high level athletes. The session will address injuries noted during the rapid rise in sports participation after a prolonged time away activity. There will be an emphasis on rehabilitation and return to sports and healthy fitness. The discussion will address the elite athlete however the principles addressed will be applicable to recreational athletes as well.\nLearning Objectives: Understand new emerging data on knee injuries in skeletal immature athletes and develop a plan when athletes are cleared to return to play Understand the common presenting symptoms of knee injuries in young athletes and the intricacies of returning to activity Understand the anatomic, physiologic and behavioral differences that make the injuries described unique and varied in the pediatric population Speaker:\nThis seminar focuses on orthopaedics and was delivered at a virtual event titled, “Returning to Sports for Elite Youth Athletes,” on August 17, 2021.\nAdditional CHOP Resources: Sports Medicine and Performance Center Division of Orthopaedics Upcoming Healthcare Professionals Events Content Disclaimer\nBy starting this module, you agree to our Content Disclaimer and Terms of Service.\nIf this is your first time attempting to login to the new website with an existing account, you will first need to reset your password before logging in.Lost Your Password?\nError: Please check your confirmed email address.\n**By selecting “Yes”, you consent to receive information from CHOP. Once you have decided to receive such communications, you may later decide to stop receiving these communications. If you want to stop receiving these communications, you may send an email message to chopopensupport@chop.edu.", "pred_label": "__label__POS", "pred_score_pos": 0.5898413062095642} +{"content": "From the Inside Out\nDiscussion Questions\nHave you known people who seemed to present “a good, Christian” exterior but were later exposed as creepy or evil? How would you describe your struggle with matching your inside attitudes with your outside behaviors?\nNotice Jesus’ response to the Pharisees in Mark 7:5-7. What words from Isaiah did Jesus apply to this group of outwardly religious men? How can we today be guilty of the same sins?\nJesus reserved harsh words for the outwardly religious of His day—the scribes and the Pharisees. Read Matthew 23:1-13. Take a moment to highlight the specific behaviors Jesus criticized.\nRead Matthew 23:23-28. Again, notice more characteristics of the scribes and Pharisees. Why does Jesus tell them to focus on the inside of the cup and dish first? What does that mean?\nIn spite of their impure motives, the scribes and Pharisees looked like upstanding, God-fearing people in their behavior. Read Matthew 5:20. How much better would you have to live to possess a righteousness that “exceeds” that of the scribes and Pharisees. Is it possible that the righteousness Jesus is describing is not connected with your outward behavior at all (compare Romans 3:21-26)?\nPaul encourages young Timothy to exercise physically and spiritually. Read 1 Timothy 4:8. How are you exercising toward godliness, beginning first with your insides? How would you assess the health of your current spiritual condition?\nDespite our romanticism about the early church, they had their fair share of problems - favoritism, theological arguments, and divisions (to name a few). Yet there remained a vision of an abundant church - full of energy, unity, and life. While the church today...\nA believer's identity is in Christ. In Him we find true life, meaning, and purpose. Yet, it is common for believers to take their eyes off of Jesus and begin substituting other things in His place. We look for other ways to identify ourselves often choosing how we...\nIt shouldn’t surprise us that through the centuries, superstitions arise and thrive even among well-meaning church people. Most of these superstitions are based on a desire for a kind of good luck charm in a life filled with uncertainty and hardship. Even the practice...\nIt is great to gather as the church. But we are also told by Jesus to “go” as the church, sharing God’s word with others and making them disciples. Fulfilling the Great Commission is not an option or a suggestion. It is a command to each of us as believers to actively...\nWhile God never changes in His nature, He does change the way He works with human beings. Jesus announced a significant change when He held up a cup and identified it with His blood that would establish a new covenant. After being raised from the dead, Jesus told His...", "pred_label": "__label__POS", "pred_score_pos": 0.5020078420639038} +{"content": "Improve Your Versatility With Dedicated Ground Logistics\nLogistics solutions often involve a variety of different transportation methods. Ground, air and sea typically all come into play when moving product. However, ground transportation is one of the more complicated forms of transportation when compared to all the others.\nDedicated Ground Logistics\nDedicated ground logistics also can make a lot of sense for your business. Dedicated ground logistics can be used for both short and long-distance shipping and can be customized to your specific needs. One of the greatest benefits of dedicated ground logistics is its flexibility.\nWith the current environment, including wildfires throughout the western United States, hurricanes in the south, as well as pandemic uncertainties, the carrier market remains extremely tight. As a result, shippers must work to differentiate themselves and that includes providing superior visibility into each shipment. Additionally, with the increased complexity created by a driver shortage, ensuring you are maximizing the right dedicated solutions brings added value to your business.\nDedicated Logistics Trucking\nDedicated logistics trucking and delivery can provide shippers with guaranteed capacity and exceptional service. Through vehicles such as dry vans, flatbeds, refrigerated, heavy haul, or specialized freight, customers can find the right dedicated truck solutions to meet their specific business needs.\nGround Logistics\nGround Logistic options typically include Less-than-truckload (LTL) and full truckload (FTL). Less-than-truckload refers to goods and commodities that do not fill up an entire truck. This allows for other shippers to join together for smaller shipments. Because LTL shipments often combine multiple loads and make several different stops, finding the right LTL trucking company is crucial. An ideal partner will create a solution that initiates cost savings, mitigates risk, optimizes your network and meets specific delivery needs. The complex pricing structure of LTL freight can include factors such as freight classifications, weight pricing, freight provisions, destination and speed. The right partner will simplify this formula, allowing you to get the best value to move your freight.\nFull-truckload (FTL) is when an entire truck is dedicated to one shipper. If a shipper chooses a FTL solution, it often means that the shipper has enough cargo to fill the entire space of the trailer in terms of weight and/or volume. It could also mean that the products are hazardous and/or fragile. FTL shipments typically save money and optimize efficiency. FTL is frequently ideal for more fragile cargo because the product is not unloaded until it reaches its final destination, reducing the chance for damage.\nAnother significant benefit of dedicated trucking revolves around safety. Vehicles are often equipped with backup alarms; collision avoidance and lane departure systems; stability control systems; air disc brakes; electronic driver logs; onboard telematics and vehicle diagnostics systems; speed governors; and advanced visibility LED headlights all help to provider a safer driver experience, reduce crashes and improved delivery services.\nEpes is Uniquely Positioned to Meet Your Dedicated Ground Logistic Needs\nDedicating ground logistics remains a key piece of Epes. We provide dedicated ground logistics to a variety of industries. With our commitment to service and our strategically located network of terminals, we can offer additional capacity and equipment as needed to help our customers through their peak shipping seasons and surges in business. Epes is a business unit of Penske Logistics. Visit epestransport.com to learn more about Epes freight solutions.", "pred_label": "__label__POS", "pred_score_pos": 0.5836856961250305} +{"content": "Bridge restorations are typically secured in the mouth with a strong dental-grade cement. This is meant to hold them firm through the course of the daily rigors of chewing and grinding food. Yet there are times when a blow to the face, an oral emergency, or a bacterial complication from gum disease can potentially weaken this strong bond. Should this... read more »\nYour dentist, Dr. Mark Andrews, designed your dental bridge from durable materials before securing it onto the abutments with a strong dental adhesive. This makes it durable enough for biting, chewing and grinding most normal foods. However, there are instances when your bridge might be damaged by something abnormal. This could be something as traumatic as a blow to the... read more »\nIt’s estimated by the American Dental Association that an average of three million teeth are knocked out each year during athletic activities. In most cases, pieces of the tooth still remain in the socket and they must be extracted to prevent pain and further complications. Once your gums have healed after the extraction, our Mark Andrews, D.D.S. team can completely... read more »", "pred_label": "__label__POS", "pred_score_pos": 0.7617056369781494} +{"content": "Paper: Polarization Observations of Molecular Clouds Volume: 343, Astronomical Polarimetry: Current Status and Future Directions Page: 321 Authors: Whittet, D.C.B. Abstract: Polarization arises from alignment of interstellar dust grains in the presence of a magnetic field. However, the efficiency with which polarization is produced per unit dust column varies strongly with environment, presumably because the alignment mechanism is sensitive to local physical conditions. Moreover, the detailed physics of alignment is not well understood. The reliability with which observations of polarization trace magnetic field structure within dense molecular clouds is therefore controversial. Observations relevant to studies of both alignment and growth of dust within molecular clouds are discussed in this review. Grains responsible for polarization within dense clouds are shown to have undergone significant growth by coagulation. In the TMC–1 clump, grains appear to be coagulating and growing icy mantles simultaneously, whereas in ρ Oph coagulation dominates. Ice-mantled grains are aligned within externally-heated clouds, but with low efficiency unless a local embedded source of luminosity is present. This result strongly suggests that spin-up by radiative torques is the dominant mechanism leading to alignment of grains within molecular clouds.", "pred_label": "__label__POS", "pred_score_pos": 0.9206587672233582} +{"content": "Background: Computational fluid dynamic (CFD) simulations have greatly improved the understanding of nasal physiology. We postulate that simulating the entire and repeated respiratory nasal cycles, within the whole sinonasal cavities, is mandatory to gather more accurate observations and better understand airflow patterns. Methods: A 3-dimensional (3D) sinonasal model was constructed from a healthy adult computed tomography (CT) scan which discretized in 6.6 million cells (mean volume, 0.008 mm 3 ). CFD simulations were performed with ANSYS©FluentTMv16.0.0 software with transient and turbulent airflow (k-ω model). Two respiratory cycles (8 seconds) were simulated to assess pressure, velocity, wall shear stress, and particle residence time. Results: The pressure gradients within the sinus cavities varied according to their place of connection to the main passage. Alternations in pressure gradients induced a slight pumping phenomenon close to the ostia but no movement of air was observed within the sinus cavities. Strong movements were observed within the inferior meatus during expiration contrary to the inspiration, as in the olfactory cleft at the same time. Particle residence time was longer during expiration than inspiration due to nasal valve resistance, as if the expiratory phase was preparing the next inspiratory phase. Throughout expiration, some particles remained in contact with the lower turbinates. The posterior part of the olfactory cleft was gradually filled with particles that did not leave the nose at the next respiratory cycle. This pattern increased as the respiratory cycle was repeated. Conclusion: CFD is more efficient and reliable when the entire respiratory cycle is simulated and repeated to avoid losing information. Keywords: 3D model; Computational fluid dynamics (CFD); airflow; nasal airway; nasal cavity; physiology; velocity; wall shear stress.\n© 2018 ARS-AAOA, LLC.", "pred_label": "__label__POS", "pred_score_pos": 0.9697444438934326} +{"content": "Abstract\nHIV partner notification involves contacting sexual partners of people who test HIV positive and referring them to HIV testing, treatment, and prevention services. To understand values and preferences of key and general populations in Rakai, Uganda, we conducted 6 focus group discussions and 63 in-depth interviews in high prevalence fishing communities and low prevalence mainland communities. Participants included fishermen and sex workers in fishing communities, male and female mainland community members, and healthcare providers. Questions explored three approaches: passive referral, provider referral, and contract referral. Qualitative data were coded and analyzed using a team-based matrix approach. Participants agreed that passive referral was most suitable for primary partners. Provider referral was acceptable in fishing communities for notifying multiple, casual partners. Healthcare providers voiced concerns about limited time, resources, and training for provider-assisted approaches. Options for partner notification may help people overcome barriers to HIV serostatus disclosure and help reach key populations.\nKeywords General populations HIV/AIDS Key populations Partner notification Sex workers ASJC Scopus subject areas Social Psychology Public Health, Environmental and Occupational Health Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.7622402310371399} +{"content": "Botany has always been a highly visual science, and women artists and illustrators have played a key role in the creation and dissemination of botanical knowledge. While the exhibition’s narrative begins in the seventeenth century, this panel brings together three contemporary artists and illustrators who are engaging with and transforming the tradition of botanical representation. As scientific illustrator for the National Museum of Natural History, Alice Tangerini has worked closely with botanists and illustrated over one thousand species of plants in scientific literature. She shares the methods of creating her information-rich pen-and-ink drawings, and the changes in scientific illustration brought by the digital age. Nirupa Rao is a botanical artist from Bangalore, India, who works closely with scientists and conservationists to document the extraordinary biodiversity of the Western Ghats. Her goal is to educate the public in environmentalist practices both through initiatives on the ground and her multiple publications. Temitayo Ogunbiyi is an artist and curator who moves between the US, Jamaica, and Nigeria. Following a residency at the Smithsonian in 2018, Ogunbiyi has created a series of botanical drawings on herbarium paper that engage with natural history collections and the historical practices that underlay their formation. The panel discusses the varied artistic processes employed by these three practitioners to explore the scientific, aesthetic, historical, and environmental interests that inform their work.\nPanelists Temitayo Ogunbiyi’s art practice moves between drawing, painting, sculpture, and installation, responding to and forging dialogues between global current events, anthropological histories, and botanical cultures from her perspective as a Nigerian-Jamaican-American. Systems that capture, mediate, and direct the movement of people, information, and matter are recurring subjects of investigation in her practice. In 2018, Ogunbiyi built her first functional playground, appropriating construction materials and conventional household items into a composition of nonprescriptive stimuli. The artist has made four functional playgrounds to date. Ogunbiyi is the recipient of several fellowships and awards, including a 2020–2021 Digital Earth Fellowship, a 2018 Smithsonian Artist in Research Fellowship, and a 2014 Ford Foundation Fellowship. Her artwork has been exhibited at the Madre Museum (Naples, Italy), the 2019 Lagos Biennial, the Pulitzer Foundation for the Arts, the Centre for Contemporary Art Lagos, the Museum of Contemporary African Diasporan Arts (Brooklyn, New York), the Perm Museum of Contemporary Art (Perm, Russia), a curatorial publication for the 10th Berlin Biennale, the Fries Museum (Berlin), and the 2nd Lagos Biennial. She lives and works in Lagos, with her young family. Nirupa Rao is a botanical illustrator based in Bangalore, India. Her work is inspired by regular field visits into the wild and informed by close collaboration with natural scientists to achieve accuracy. As a National Geographic Young Explorer, Rao received a grant to create her book Hidden Kingdom: Fantastical Plants of the Western Ghats (2019). She has also published Pillars of Life: Magnificent Trees of the Western Ghats (2018), a debut project in collaboration with naturalists Divya Mudappa and T. R. Shankar Raman of the Nature Conservation Foundation. She illustrated the cover of Amitav Ghosh’s latest novel, Gun Island, and rejacketed four of his older novels for Penguin Random House. In collaboration with Alice Tangerini, staff illustrator for the Botany Department at the Smithsonian’s National Museum of Natural History, has been specializing in drawing plants since 1972. She works with pen and ink, graphite, and—recently—digital color. She has illustrated over one thousand species of plants appearing in scientific periodicals, floras, and botanical and nature books. Tangerini teaches classes in illustration techniques, presents lectures on botanical illustration, and juries shows in botanical gardens and academic institutions. Her responsibilities in the Botany Department also include managing and curating an extensive collection of botanical illustrations. In 1999, Tangerini received the Distinguished Service Award from the Guild of Natural Science Illustrators. In 2008, she was honored with the Excellence in Scientific Botanical Art award from the American Society of Botanical Artists, of which she is a past board member. In 2020, the Linnean Society of London honored Tangerini with the Jill Smythies Award for outstanding illustrations that portray diagnostic characteristics.", "pred_label": "__label__POS", "pred_score_pos": 0.7364600300788879} +{"content": "Bahia Bahia Sod\nBahiagrass (Paspalum notatum Flugge) was introduced from Brazil in 1914. It was originally used as a pasture grass on the sandy soils of the southeastern United States. Additional varieties have been introduced since that time for use as lawn grasses. Bahia grass is a low-maintenance lawn grass that does well with limited water and fertilizer inputs. Bahia grass is commonly found on highways, roads median and the side of the road. Varieties currently available do not produce a carpet-like, dense lawn like some other warm-season lawn grasses.\nBahiagrass forms an extensive, deep root system. It sustains better than other grasses in infertile, sandy soils and does not require high inputs of water or fertilizer. This makes it a good choice for home sites on large lots or acreage or for anywhere that there is no irrigation system. It should be noted that during extended drought periods, bahiagrass will go into a drought induced dormancy and turn brown until conditions become favorable for regrowth.", "pred_label": "__label__POS", "pred_score_pos": 0.531551718711853} +{"content": "Climate change represents one of the greatest global health threats of our time. In choosing Healthy Environment, Healthy Kidneys as the theme for the 2021 fully virtual Congress, the ERA-EDTA highlights the central role of nephrologists and other health professionals in advocacy for global efforts to reduce emissions and protect against climate change.", "pred_label": "__label__POS", "pred_score_pos": 0.8341981172561646} +{"content": "After the fall of communism, the healthcare systems of Central and Eastern European countries underwent enormous transformation, resulting in departure from publicly financed healthcare. This had significant adverse effects on equity in healthcare, which are still evident. In this paper, we analyzed the role of government and households in financing healthcare in eight countries (EU-8): Czechia, Estonia, Hungary, Latvia, Lithuania, Poland, Slovakia, and Slovenia. A desk research method was applied to collect quantitative data on healthcare expenditures and qualitative data on gaps in universal health coverage. A linear regression analysis was used to analyze a trend in health expenditure over the years 2000-2018. Our results indicate that a high reliance on out-of-pocket payments persists in many EU-8 countries, and only a few countries have shown a significant downward trend over time. The gaps in universal coverage in the EU-8 countries are due to explicit rationing (a limited benefit package, patient cost sharing) and implicit mechanisms (wait times). There is need to increase the role of public financing in CEE countries through budget prioritization, reducing patient co-payments for medical products and medicines, and extending the benefit package for these goods, as well as improving the quality of care.\nKeywords: Central and Eastern European countries; healthcare financing; universal health coverage.", "pred_label": "__label__POS", "pred_score_pos": 0.9114761352539062} +{"content": "The Arizona State Supreme Court on Friday ruled that child-welfare officials must offer reunification services to certain inmates before terminating parental rights.\nThe ruling states that officers constitutionally must provide services, like visitation between parent and child, to inmates facing long prison sentences.\nSpecifically, the case examined the circumstances of a father whose parental rights to two young children were ended by a lower court. In the ruling, the Justices maintained the termination of rights due to the children’s best interest; however, while issuing the decision on the appeal, the Court established the reunification services requirement.\nPrior to the ruling, Arizona law did not require the state to offer services to continue the relationship between parents, who are inmates, and children.\nHowever, based on a previous Supreme Court ruling, “Parents enjoy a fundamental liberty interest in ‘the care, custody, and management’ of their children.”\n“The state has a vital interest in the status of the parent-child relationship and, because of the importance of this interest, the state may intrude into the parent-child relationship to protect the welfare of the child and the state’s own interest in the welfare of its citizens” the ruling stated.\nHowever, the Justices maintained the right of the judiciary to terminate parental rights under some circumstances.\n“A court may terminate parental rights under certain circumstances, so long as the parents whose rights are to be severed are provided with ‘fundamentally fair procedures’ that satisfy due process requirements,” the opinion continued.\nWhile the Court acknowledged that it would be difficult to maintain a relationship with their children while in prison, the Justices expressed that “an incarcerated parent can maintain a bond with a child in other ways, such as through visits, phone calls, letters, pictures, and gifts.”\n— — —", "pred_label": "__label__POS", "pred_score_pos": 0.5267190933227539} +{"content": "The world is in turbulence as those left behind by free trade express their anger. Britain left behind their most important trade relationship, while America is considering tearing up all their agreements. The world economy will be the worse for it. As economists ponder how the rubes can choose an economically worse off position, they fail to realize that measuring benefits in dollars is not always the goal. While giving the dignity of work to the impoverished people of the d\nInvesting is not easy, and few people do it well over an extended period. The research documents this outcome well. Despite the evidence, there are those investors who have delivered consistent performance over decades. These unique investors perform in markets both public and private; from identifying value, to improving business operations, or understanding strategy. These investors share three core beliefs: people that excel in their field of expertise deliver value; busin", "pred_label": "__label__POS", "pred_score_pos": 0.9696173071861267} +{"content": "Post-therapy whole-body scan with abnormal radioactive iodine localized to the head of two women\nA 25-year-old woman was referred for radioactive iodine remnant ablation for multifocal micropapillary thyroid carcinoma.\nA thyroidectomy performed after a fine-needle aspiration, suspicious for papillary thyroid carcinoma, was found and revealed three papillary microcarcinoma measuring 0.2 cm, 0.6 cm and 0.6 cm in the right lobe and a 0.2-cm papillary microcarcinoma in the left lobe. One perithyroidal lymph node was removed with no tumor identified. The patient was referred by her outside endocrinologist for radioactive iodine (RAI) ablation. Despite a long discussion stressing that she was at very low risk for death and recurrence indicated by her young age, American Joint Committee on Cancer (AJCC) stage I and her low risk for recurrence per the 2009 American Thyroid Association thyroid nodule and cancer guidelines, the patient was anxious and worried, and requested RAI ablation.\nShe had remnant ablation with 50 mCi I-131 with a thyroid-stimulating hormone of 73.07 mU/L and a low thyroglobulin 1.4 ng/mL with a negative thyroglobulin antibody level less than 20 IU/mL. Seven days later, a post-therapy whole-body scan was obtained that showed a focus of avid uptake in the thyroid bed from a postsurgical thyroid remnant. There was also diffuse tracer localized along the periphery of her head in the location of the skull (Figures 1A, B). The patient had washed her hair between the dose and the 7-day post-therapy scan, but she complained of extreme anxiety and sweating during the post-therapy scan.\nAnother patient\nA second patient, a 54-year-old woman, was referred for RAI ablation. She had a total thyroidectomy for a multifocal micropapillary thyroid carcinoma with feature of a tall cell variant with lymphovascular and capsule invasion with positive margins. Four metastatic lymph nodes were removed from the lateral neck (levels 3 and 4). Her past medical history was positive for oligomenorrhea, but since her surgery 2 months before, she was amenorrheic with severe daytime and night sweats. This patient was at moderate risk for death and recurrence based on the histological variant of her tumor, lymphovascular and capsule invasion and lateral neck nodes (AJCC stage IV A).\nShe had RAI therapy with 149 mCi I-131 with a TSH of 49.02 mU/L and a low thyroglobulin 3.6 ng/mL with a negative thyroglobulin antibody level less than 20 IU/mL. Seven days later, a post-therapy whole-body scan was obtained that showed a focus of avoid uptake in the thyroid bed from the postsurgical thyroid remnant and tracer located along the periphery of her head in the location of the skull (Figures 1C, D). The patient noted that she was very anxious and had a drenching sweating episode during her whole-body scan.\nPhoto courtesy of: Stephanie L. Lee, MD, PhD\nPattern of uptake\nOne year after the initial RAI therapy, both patients had a recombinant human TSH-stimulated RAI whole-body scan that demonstrated no abnormal uptake, and the stimulated thyroglobulin was unmeasurable, suggesting the absence of persistent disease.\nThe specificity of I-131 whole-body scans for the initial staging and detecting postoperative local and distant metastatic disease is excellent. Radioiodine whole-body imaging is the most accurate method in the diagnosis of metastases from differentiated thyroid cancer. However, false-positive images occur at sites of body fluid stasis such as in a renal cyst, sinus mucocele and hematoma or cutaneous contamination by radioiodine in either saliva or urine.\nIt was felt that the diffuse uptake along the peripherally of the skull in both cases was a contamination artifact likely due to physiological scalp sweat due to anxiety and postmenopausal diaphoresis. It is very unlikely, with the low level of thyroglobulin levels in the presence of a significantly elevated TSH that this peripheral skull trapping was due to widely metastatic disease to the calvarium. This pattern of uptake on a RAI whole-body scan has been previously described and named the “helmet sign.â€�\nStephanie L. Lee, MD, PhD, is associate chief in the section of endocrinology, diabetes and nutrition and associate professor of medicine at Boston Medical Center. She is also an Endocrine Today Editorial Board member.\nFor more information: Ash L. J Nucl Med Technol. 2004;32:164-165. Matheja P. J Nucl Med. 1997;38:1022-1024. Ong SC. Clin Nucl Med. 2004;29:164-166. Salvatori M. Clin Nucl Med. 1997;22:380-384. Schlosser J. Thyroid. 2007;17:81-82.", "pred_label": "__label__POS", "pred_score_pos": 0.5622926950454712} +{"content": "In light of recent world events, many retail businesses have needed to adapt and migrate to online operations in order to stay relevant. With B2B buyers’ expectations significantly influenced by their B2C experiences, it’s crucial for B2B companies to make this shift as well in order to stay competitive.\nAccording to the Australian Bureau of Statistics, total online sales averaged an annual rise of 65% between March 2020 and January 2021. With the increasing prevalence of online sales for retail businesses, B2B businesses can’t afford to fall behind and miss out on these major growth opportunities.\nThe segment is witnessing unprecedented growth across the globe, with McKinsey research indicating that 75% of B2B buyers preferring the online route to in-person sales. Additionally, only 20% of B2B buyers plan to return to in-person sales in the post-COVID marketplace.\nIn the long run, having your own dedicated B2B e-commerce platform is an investment that will pay off.\nWhat is a B2B E-Commerce Platform?\nA B2B e-commerce platform is a comprehensive software solution for enterprises, typically aimed at manufacturers, wholesalers, distributors, and other B2B organisations. They handle all aspects of selling products or services to other business organisations, including inventory management and payments.\nA major advantage of many modern B2B e-commerce platforms is the inclusion of self-service functionalities for buyers, helping businesses to manage marketing and sales strategies efficiently across many channels. B2B e-commerce platforms play a major role in delivering superior customer service.\nCompetitive Advantages of B2B E-Commerce Platforms\nMany advantages of online B2B platforms are related to the changing preferences and expectations of the modern B2B buyer. The reasons behind this are evident – at a personal level, B2B buyers are also online retail customers and a growing percentage of them are millennials, a demographic accustomed to the convenience and comfort of shopping online.\nCompanies can no longer rely on basic websites or email marketing to attract and retain customers. In order to meet their growing expectations, a full-fledged B2B e-commerce solution is essential. But what are its key competitive advantages?\n1. Catering to New Online Buyers\nEven in the US, home to one of the world's largest B2B e-commerce marketplaces, online sales account for less than 20% of the total B2B segment. However, this number is steadily increasing and the COVID-19 pandemic has only accelerated the trend.\nIn Australia, which has historically lagged behind other developed nations in adopting online shopping, the pandemic has created a new reality. Out of necessity, millions have been forced to go to online marketplaces like Amazon and eBay.\nThis includes a significant proportion of baby boomers and Gen X consumers. Inevitably, many members of the latter generation may also be involved in making B2B purchasing decisions in their professional lives. A B2B vendor offering a convenient online shopping experience will hold a competitive edge among this demographic.\nUnfortunately, one cannot hope for the situation to go back to pre-pandemic levels in the post-COVID marketplace. Only a small minority of B2B buyers have expressed willingness to return to traditional in-person B2B buying experiences.\n2. Adapting to Rapidly Shifting Buyer Expectations\nWhile the older generation is more resistant to engaging in digital experiences, the opposite is true in the case of millennials. As more of this generation enters senior roles of management in business organisations, this will start to have a major impact on B2B buying decisions.\nAs a tech savvy generation, they are comfortable with online buying – over 60% of their shopping is carried out on e-commerce platforms. Traditional marketing and outreach campaigns will not work on these buyers, as their expectations are considerably higher and evolving constantly.\nAs B2B buyers, they seek interactive and authentic content from sellers. Instead of relying purely on marketing information, they actively seek out additional information online. To meet this demand, vendors have to focus on omnichannel marketing, with a special emphasis on mobile.\nIn fact, the vast majority of B2B transactions now begin with a basic mobile search. Speed and convenience are of the essence here – the modern buyers value vendors that are flexible enough to deliver services on demand.\nTraditional offline B2B channels are not equipped to meet these buyer expectations but B2B e-commerce platforms are designed to deliver all these features and more.\n3. Increased Emphasis on Digital Experiences\nThe modern B2B buyer puts a premium on the overall buying experience. Instead of generic, cookie-cutter marketing strategies, B2B sellers have to focus on more personalised services – uniquely tailored to the needs of individual buyers.\nConsistency is key here and the interactive content has to be seamless across multiple channels – apps, websites, social media, desktops and mobile screens. Across the entire buyer journey, all interactions should be smooth, hassle-free, and uniform across all channels.\nB2B firms should also pay special attention to feedback from buyers, constantly tweaking and improving the system to deliver better experiences. All this requires a tightly integrated platform that brings marketing, sales, CRM, and IT teams all on the same page.\nUniting Marketing, Sales and IT Teams on a Single Platform\nIn business, it is more important than ever to establish and build connections with your customers. Building lasting client relationships is more common and rewarding in the B2B segment.\nDigital experiences are often a critical factor that make the difference between a lead and a sale. A digital experience platform (DXP) is a software solution focused on nurturing deep relations with clients.\nFor example, Liferay's B2B Commerce solution is particularly powerful in comparison to pure play e-commerce platforms due to Liferay DXP’s ability to unite content, commerce and portals to serve the B2B customer journey. This helps to bring your marketing, sales, and IT teams on a single online platform, encouraging better coordination between teams as they serve your customers.\n1. Marketing – Improved Customer Satisfaction\nThe system has a plethora of tools that allow marketing teams to deliver content-rich product catalogues and immersive product discovery journeys for your buyers. At the same time, marketers can tap into advanced audience analytics, helping deliver targeted and personalised marketing content to prospective buyers.\n2. Sales – High-Value Interactions On-Demand\nWhile self-service channels have become increasingly popular, B2B vendors often have complex catalogues that can confuse some buyers. With built-in B2B sales tools, DXPs often give sales teams the ability to step in to take action on behalf of accounts when required, without interfering with other channels. With advanced insights, sales teams can act as on-demand experts or consultants who assist B2B buyers in need.\n3. IT – Lower Maintenance and Increased Value Creation\nIn many traditional e-commerce platforms, IT teams are often too busy handling basic requests from sales and marketing departments. This reduces the time and resources available for critical tasks like network security, optimisation, and feature development.\nDXP solutions empower marketing and sales teams to handle the daily tasks with relative autonomy, allowing IT teams to focus on creating business value. DXPs bring commerce-related customer data onto one platform which can be integrated with your existing customer-facing systems, helping to provide consistent user experiences.\nThe Future of B2B E-Commerce\nThe impact of the recent world events on B2B e-commerce has been far-reaching and many changes are likely to stay. As more buyers experience the convenience of online purchasing, B2B firms will have to adapt and improve their e-commerce capabilities.\nA B2B e-commerce platform is a necessity in this ‘new normal’ for B2B organisations. To take this one step further and to achieve maximum ROI and scalable growth, consider how a DXP can help unite content, commerce and portals to serve the entire B2B customer journey.", "pred_label": "__label__POS", "pred_score_pos": 0.7411264181137085} +{"content": "The UAE's Economic Diplomacy\nThrough its global network of missions and embassies, the Ministry of Foreign Affairs and International Cooperation (MoFAIC) aims to attract foreign investments, encourage outbound investments, promote trade, and strengthen bilateral and multilateral economic relationships. These operations make up the core of the UAE's economic diplomacy, which ultimately supports the long-term economic and societal needs of the UAE highlighted under Vision 2021 and the 2071 Centenary Plan.\nSupporting a Diversified Economy\nThe UAE continues to create a diversified economy while still sustainably reaping the benefits of its abundant natural resources. MoFAIC plays a vital role in ensuring that the UAE benefits from global economic trends by consolidating and strengthening its position as a key player on the world stage. The UAE's economy is already the Arab World's second-largest, with robust and sustainable growth generated through tourism, transport and logistics, financial services, real estate, banking, and renewable energy. Increasingly, the UAE is looking to the future economy, prioritising investments in education, information technology, artificial intelligence, health, and industrial manufacturing.\nInward and Outward Investment\nThe UAE has an impressive track record of attracting Foreign Direct Investment (FDI) through favourable tax regulations, developed infrastructure, and minimising barriers to establishing a business. The UAE continually demonstrates its determination to provide the best possible regulatory environment for investments. The 2018 FDI Law opens up numerous economic sectors for 100 percent foreign ownership. This new framework supports investments that build regional and global value through production chains focused on advanced and high-value industries.\nThe UAE has also worked to facilitate outward investment, including establishing successful sovereign wealth funds. Through these funds, the UAE had become a significant investor in many parts of the world. The returns generated by these funds are invested back into the development of the UAE, with a substantial portion going to projects in energy, industry, communication and information technology, infrastructure, healthcare, and renewable energy.\nMoFAIC ensures clarity over taxation and investment issues by supporting national efforts to sign bilateral Double Taxation Agreements and Bilateral Investment Treaties (also known as Investment Protection and Promotion Agreements). MoFAIC also assists in signing bilateral aviation agreements, which is critical given the UAE's aviation sector size, hosting two of the world's leading airlines: Emirates and Etihad.\nTrade Facilitation\nThrough substantial investments in infrastructure, the UAE has emerged as a regional and global trading hub. This is further bolstered by the UAE's strategic geographic location between Asia, Europe, and Africa and is a gateway to the Middle East. In seeking to increase trade volume further, the UAE is a leading proponent of global free trade and has been a member of the World Trade Organization since 1996.\nDiplomacy in Partnership\nMoFAIC works closely with Emirate-level investment promotion agencies, the private sector, sovereign wealth funds, business councils, and other economic actors to ensure successful outcomes through economic diplomacy. For example, in late 2019, the Emirates Diplomatic Academy hosted the Economic Diplomacy Seminar for the UAE and Saudi Arabia, strengthening the economic might of the two nations.\nIn partnership with the Prince Saud Al-Faisal Institute of Diplomatic Studies, the event supported Emirati and Saudi entities in foreign markets, evaluated the level of global integration of their economies, and promoted foreign direct investments to support job creation in the two countries.", "pred_label": "__label__POS", "pred_score_pos": 0.7587301731109619} +{"content": "Coral reefs provide a wide array of ecosystem services and harbor some of the highest levels ofbiodiversity on the planet, but many reefs are in decline worldwide. Tracking changes isnecessary for effective resource management. Biological sounds have been suggested as a meansto quantify ecosystem health and biodiversity, but this requires an understanding of naturalbioacoustic variability and relationships to the taxa present. This investigation sought tocharacterize spatial and temporal variation in biological sound production within and amongreefs that varied in their benthic and fish diversity. Multiple acoustic recorders were deployed forintensive 24-hour periods and longer term (~4-month) duty-cycled deployments on three reefsthat varied in coral cover and fish density. Short-term results suggest that while there werestatistically significant acoustic differences among recorders on a given reef, these differenceswere relatively small, indicating that a single sensor may be suitable for acoustic characterizationof reefs. Analyses of sounds recorded over ~4 months indicated that the strength of diel trends ina low frequency fish band (100-1000 Hz) was correlated with coral cover and fish density but thestrength of high-frequency snapping-shrimp (2-20 kHz) trends was not, suggesting that low-frequency recordings may be better indicators of the species assemblages present. Power spectravaried within reefs over the deployment periods, underscoring the need for long-durationrecordings to characterize these trends. These findings suggest that, in spite of considerablespatial and temporal variability within reef soundscapes, diel trends in low-frequency soundproduction correlate with reef species assemblages.", "pred_label": "__label__POS", "pred_score_pos": 0.5813301801681519} +{"content": "dc.description.abstract Women in Zanzibar are socially and economically disadvantaged in many aspects. In\nview of this, the government made efforts to ensure women empowerment through\ndevelopment programmes such as Agriculture Services Support Programme (ASSP).\nHowever, the extent of socio-economic empowerment on women in rural areas is scanty.\nTherefore, this study aimed at assessing the contribution of ASSP intervention to socio-\neconomic empowerment of rural women in Zanzibar. Specifically, the study assessed the\nASSP empowerment strategies, women participation levels and attitude towards ASSP.\nThe study also compared empowerment levels between programme and non-programme\nmembers. Primary data were collected using a structured questionnaire from 200 women\nin ten shehia of Mkoani district. Women empowerment levels were measured by using a\nWomen Empowerment Index (WEI). The hypothesis to demonstrate the differences of\nwomen empowerment between programme and non-programme members was tested\nusing Mann-Whitney U-test. The results showed high extent of women participation in\nstudy visits, training and regular meetings and moderate participation was noted on\nParticipatory Action Research (PAR) and Participatory Rural Appraisal (PRA). Women\nbenefited socially and economically due to their participation in ASSP. The results\nsuggested high level of empowerment for women in the ASSP programme. This was\nconfirmed by Mann-Whitney U-test, which revealed increased in women decision making\non production resources, increase in income and contribution on household expenses.\nHowever, mobility decision and asset ownership did not differ among ASSP and non-\nASSP members due to Islamic socialization culture. Women’s attitude towards ASSP\nwas positive indicating that strategies used to empower women were appropriate, while\nthe lack of investment capital and time constraints hampered women's participation in the\nprogramme. Based on these findings, it is concluded that the initiative taken by theiii\ngovernment through ASSP left significant change on rural women's socio-economic status\nin Mkoani district. However, consideration of the women financial support is among other\nthings recommended for other coming women empowerment programmes. en_US", "pred_label": "__label__POS", "pred_score_pos": 0.8740091323852539} +{"content": "Correspondence: Address correspondence to Kristi Rahrig Jenkins, The Institute for Social Research, The University of Michigan, 426 Thompson St., Box 1248, Room 2044, Ann Arbor, MI 48106-1248. E-mail: kristirj{at}isr.umich.edu\nThis study has two purposes. First, it determines if Purpose:\nKey Words: Obesity Overweight Functional impairment Health conditions This article has been cited by other articles:\nB. Bruce, J. F. Fries, and H. Hubert\nRegular Vigorous Physical Activity and Disability Development in Healthy Overweight and Normal-Weight Seniors: A 13-Year Study\nAm J Public Health, July 1, 2008; 98(7): 1294 - 1299.\n[Abstract] [Full Text] [PDF]\nV. L. Forman-Hoffman, K. K. Richardson, J. W. Yankey, S. L. Hillis, R. B. Wallace, and F. D. Wolinsky\nImpact of Functional Limitations and Medical Comorbidity on Subsequent Weight Changes and Increased Depressive Symptoms in Older Adults\nJ Aging Health, June 1, 2008; 20(4): 367 - 384.\n[Abstract] [PDF]\nB. M. Rogozinski, J. R. Davids, R. B. Davis, L. M. Christopher, J. P. Anderson, G. G. Jameson, and D. W. Blackhurst\nPrevalence of Obesity in Ambulatory Children with Cerebral Palsy\nJ. Bone Joint Surg. Am., November 1, 2007; 89(11): 2421 - 2426.\n[Abstract] [Full Text] [PDF]\nE. Kramarow, J. Lubitz, H. Lentzner, and Y. Gorina\nTrends In The Health Of Older Americans, 1970 2005\nHealth Aff., September 1, 2007; 26(5): 1417 - 1425.\n[Abstract] [Full Text] [PDF]\nYing Wu, Hai Huang, Bei Wu, S. McCrone, and H.-J. Lai\nAge Distribution and Risk Factors for the Onset of Severe Disability Among Community-Dwelling Older Adults With Functional Limitations\nJournal of Applied Gerontology, June 1, 2007; 26(3): 258 - 273.\n[Abstract] [PDF]\nS. Schieman, T. McMullen, and M. Swan\nRelative Body Weight and Psychological Distress in Late Life: Observations of Gender and Race Comparisons\nJ Aging Health, April 1, 2007; 19(2): 286 - 312.\n[Abstract] [PDF]\nD. T. Villareal, M. Banks, D. R. Sinacore, C. Siener, and S. Klein\nEffect of Weight Loss and Exercise on Frailty in Obese Older Adults.\nArch Intern Med, April 24, 2006; 166(8): 860 - 866.\n[Abstract] [Full Text] [PDF]\nD. T Villareal, C. M Apovian, R. F Kushner, and S. Klein\nObesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society\nAm. J. Clinical Nutrition, November 1, 2005; 82(5): 923 - 934.\n[Abstract] [Full Text] [PDF]\nS. L. Reynolds, Y. Saito, and E. M. Crimmins\nThe Impact of Obesity on Active Life Expectancy in Older American Men and Women\nGerontologist, August 1, 2005; 45(4): 438 - 444.\n[Abstract] [Full Text] [PDF]\nMinerva\nBMJ, May 1, 2004; 328(7447): 1084 - 1084.\n[Full Text] [PDF]\nHOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS\nAll GSA journals Journals of Gerontology Series A: Biological Sciences and Medical Sciences Journals of Gerontology Series B: Psychological Sciences and Social Sciences", "pred_label": "__label__POS", "pred_score_pos": 0.5236939191818237} +{"content": "A government-funded coronavirus symptoms app has predicted the five next hotspots in the UK based on the number of people recording tell-tale signs of Covid-19, with Blackpool topping the list.\nSome 0.4% of Blackpool's population are apparently symptomatic, up by 0.17% on last week's figures, according to the Covid Symptom Study application.\nThe app does not indicate the number of recorded cases of coronavirus but predicts where they might arise based on the number of people reporting symptoms.\nBlackpool is joined by Dundee, Merthyr Tydfil, Nottingham and Halton as places on the top 10 list of places experiencing significant symptoms but which are outside current local lockdown zones.\nManchester, Kirklees, Rochdale, Salford and Blackburn with Darwen, are the other hardest-hit areas.\nBlackpool, Halton and Manchester have taken the top three spots on the list, with rates roughly 10 times the national average.\nHowever, experts are not too concerned about the latest figures as the rates were 100 times higher in April and May.\nTim Spector, professor of genetic epidemiology at King's College London, which developed the app, said: “The trends are flat which is reassuring despite the multiple small outbreaks we have been seeing across the UK in places like Manchester.\n\"Our survey data is consistent with the ONS household survey, which estimates slightly higher numbers due to the inclusion of asymptomatic cases.\"\nSome 0.4% of Blackpool's population has symptoms, based on data from the 871 app users in the town.\nThis is an increase on last week when 0.23% reported symptoms.\nHalton, which topped last week's list, has seen a slight increase in its population symptom rate, with the figure now at 0.35%.\nManchester and Merthyr Tydfil have a rate of 0.21%, while Kirklees has 0.2%, Rochdale has 0.19%, Dundee has 0.18% and Nottingham, Blackburn and Darwen and Salford have 0.17%.\nThe Covid Symptom Study app has been downloaded by over 3.9 million people and the latest figures are based on 8,798 swab tests done between August 2 and August 15.\nThe app figures show there were on average 1,265 new cases every day in the UK over the two-week period, with 20,299 currently suffering coronavirus symptoms.\nIt comes after new data revealed that Oldham - which is teetering on the brink of full lockdown - had the highest coronavirus infection rate in England, despite a sharp fall in cases.\nThe Greater Manchester town saw 187 new cases recorded in the seven days up to Monday.\nDespite its high infection rate, there has been a marked decrease since last week, updated figures from Public Health England show - with the rate plummeting from 111.8 per 100,000 to 78.8.\nDr Arif Rajpura, Director of Public Health for Blackpool Council, said: “The league table and associated figures are not representative of what is happening on the ground in Blackpool.\n“We currently have very low levels of community transmission and only a small number of positive cases reported over the past week.\n\"Earlier this week, we reported that we had no patients at all being treated for coronavirus in our local hospital.\n“It is our key objective to keep it that way and avoid any localised outbreaks by driving home the messaging around safe distancing and hygiene.\n\"We are also working closely with businesses to ensure that as the economy opens up, they are adhering to all COVID-safe guidelines to protect their staff and customer\ns.” Top 10 places on UK symptom app (% of people reporting symptoms)\n1. Blackpool - 0.4%\n2. Halton - 0.35%\n3. Manchester - 0.21%\n4. Merthyr Tydfil - 0.21%\n5. Kirklees - 0.2%\n6. Rochdale - 0.19%\n7. Dundee - 0.18%\n8. Nottingham - 0.17%\n9. Blackburn with Darwen - 0.17%\n10. Salford - 0.17%", "pred_label": "__label__POS", "pred_score_pos": 0.5491229891777039} +{"content": "Imagine walking down the street and you immediately notice an elderly man fall to the ground and appears to not be breathing. What do you do? Aside from dialing 911, would there be something you can do to help? A new Microsoft Research project is looking at ways your smartphone can help you potentially save a life.\nTypically, in a calm scenario, we can utilize a search engine, WebMD, sometimes YouTube, or any other resource for guidance on solving a dilemma. But during a stressful situation, when your adrenaline is flowing, we need a faster solution to find the information we need.\nMicrosoft Research’s Nina Mishra is working on a project that examines how people use search engines in time-critical situations and how that could translate to a phone being able to walk a person through resolving an emergency situation. Here is an example:\n\"Mishra and her co-authors developed methods that provide search engines with the ability to recognize time-critical queries. These methods enable Lisa’s phone to detect the urgency of the query and suggest that she call 911 immediately and then follow step-by-step instructions. While the ambulance is on its way, the phone advises Lisa on valuable assistance to provide. Using the location sensor on the phone, Lisa finds an automated external defibrillator nearby, and the phone suggests that she ask someone to retrieve it. The phone then tells Lisa to place the phone directly on the neighbor’s chest and to perform chest compressions directly on the phone. The accelerometer in the device explains to Lisa the correct depth of compression and how quickly they must be performed. Lisa follows the instructions, an ambulance pulls up, a life is saved.\"\nOther scenarios including a person having a stroke, how to stop severe bleeding, and how to handle a baby that is choking. Mishra's team is also collaborating with the Division of Emergency Medicine at the Stanford School of Medicine.\nThe goal is simple - have your phone detect medical emergencies with a high degree of accuracy and deliver targeted first-aid information - ultimately making your smartphone an essential asset when confronted with a medical emergency. \"Going forward,\" Mishra says, \"we envision using the richer signals of a smartphone to assist the next person in need of help.\"", "pred_label": "__label__POS", "pred_score_pos": 0.5127934813499451} +{"content": "The DRDO’s Covid task team, led by chairman G. Satheesh Reddy, undertook several crucial steps to combat the pandemic. From Sp02 (oxygen concentration)-based systems to ventilators, diagnostic kits and unique therapeutic drugs, to masks, PPE kits, oxygen plants and hand sanitisers, the DRDO was at the forefront of the war against Covid. Nearly 80,000 DRDO-designed PPE kits are being produced daily now. Over 3.5 million such PPE suits were made by HLL for industries last year.\nThe DRDO is also using medical technology designed for fighter aircraft to address the oxygen shortage across the country. Over 900 such plants have been installed across the country. The Onboard Oxygen Generation System (OBOGS) was designed to extract atmospheric air and convert it into oxygen for pilots flying the indigenous Light Combat Aircraft (LCA) Tejas. Several private sector firms, including Trident Pneumatics and L&T, manufacture and instal these plants now. They come in various sizes and can supply 250, 500 and 1,000 litres of oxygen per minute to hospitals.", "pred_label": "__label__POS", "pred_score_pos": 0.9071879386901855} +{"content": "Thursday, September 09, 2021, 6:30 PM - 7:30 PM with Dr. Glenda Dickinson, NCC, LCPC Private Practice, Upper Marlboro, MD\nTraumatic grief is a phenomenon that merges the sudden, distressing experience of trauma with the death of a loved one. It brings with it varying levels of hopelessness and often shatters the worldview of the bereaved. For some, such tragedy can result in a loss of faith, while for others the need to become more deeply immersed in their faith or involved in their religion as they seek solace is amplified. This segment of the series will address the sense-losing aspect of traumatic grief, acknowledge the crippling pain that the bereaved experience as they navigate their grief journey, recognize the role of spirituality, religion, and social support in mitigating grief, and determine ways for the bereaved to begin a sense-remaking journey. We will also take a cursory view of the prevalence of homicide in our communities as a backdrop to the traumatic grief issues that result.\nLearning Objectives: Learning Objectives: Recognizing and understanding traumatic grief and how it differs from other grief events including prolonged The role of spirituality, religion, and social support in navigating the grief What’s next for the family and the community? How could we create a meaningful situation from a sense-losing, catastrophic event?\nAbout the presenter: About the presenter:\nDr. Glenda Laurent Dickinson is a licensed clinical professional counselor with a passion for helping her clients on their journey to wellness. She embraces positive psychology and a growth-oriented, eclectic approach to treatment. Dr. Dickinson earned both her Ph.D. in Counselor Education and Supervision and her MS in Pastoral Counseling from Loyola University Maryland. She also earned an M.S.Ed. in Guidance and Counseling from Hunter College, City University of New York.\nDr. Dickinson’s research focuses on the cultural and spiritual intersections of parental grieving and posttraumatic growth among parents of homicide victims. Her study has contributed to the development of a trauma grief growth model which she uses as a framework for understanding and treating traumatic grief.", "pred_label": "__label__POS", "pred_score_pos": 0.6696690320968628} +{"content": "The CFPB outlined best practices for sharing information with state banking and financial services regulators with which it has entered into an MOU. In the Statement of Intent, the CFPB noted that the list provided was not exhaustive, and that the CFPB would use its best efforts to share information. Some of the means of information sharing include: (1) coordinating with, and provide nonbank supervision examination schedules to state regulators; (2) providing access to consumer complaint information on a systematic basis; and (3) sharing Registered Mortgage Loan Originator information. The CFPB also noted that, in connection with enforcement activities, it will, among other things, provide reasonable notification to state regulators prior to initiation of a public enforcement action, consult with regulators during the enforcement process, and engage in regular consultation to identify mutual enforcement priorities.\nAlert December 11, 2012", "pred_label": "__label__POS", "pred_score_pos": 0.5814181566238403} +{"content": "Understanding the business value of real-time analytics\nFloris van der Walt, Regional Service Delivery Manager at PBT Group Regardless of size, businesses across industries and sectors need to react much quicker to customer requests that can include everything from quotations and proposals to delivering on services. It does not stop there. Internal management, marketing initiatives, operational requirements, and more need to be done more rapidly than in the past, to ensure customer satisfaction and in return, retention. This is where analytics comes into play. Real-time analytics plays a pivotal role in gathering relevant information from the multitude of systems used in businesses today. In turn, this data is transformed into valuable information used for decision-making purposes or direct action to steer or execute work. Nuanced definition However, real-time analytics does not necessarily happen immediately due to the complexities and cost involved. Rather, it appears as the value derived in the process. The real-time aspect therefore means how information is made available to be analysed when required. Up until recently, daily extracts were used as the basis for analytics. In fact, many organisations still rely on this. The constant drive to enhance and improve has seen this starting to change into much smaller timeincrements or streamed data being used for analytics, such as transactions as they happen. Despite this growing need for more frequently updated sales reports, processing throughput charts, or parts per million quality tracking dashboards, real-time is relative to the industry that it is being applied to. For instance, services like media streaming businesses, telephony providers, or financial institutions that provide ‘instant loans’ would need to rely on real-time information to prevent delays that could negatively impact their customers. Analytics in these environments would therefore need to be ‘fast enough’ to inform processes and people to allow for insights, decisions, and actions to be taken. Deriving value Being able to react based on the most up to date information not only gives a company an advantage over its competitors, but also contributes to improved effectiveness within an organisation. Generally, benefits can be grouped as follows: Capitalising on the situation by using and applying insights from the real-time analytics to the benefit of the business. Gaining competitive advantage by selling specific products sooner than competitors, or at more affordable price. Examples can include personalised real-time marketing where SMS, WhatsApp, and other notifications are sent to customers when arriving at a mall based on their own preferences. Maintain continuous operations by understanding the status of processes, equipment, or services, and being able to act on insights to, for example: • Maintain or repair equipment before failures occur (manufacturing or processing) • Address service level issues to meet demand and expectation (Internet, data, telephony, banking services) Driving continuous improvement Additionally, in the same way that organisations can benefit from applying Kaizen principle of Continuous Improvement – i.e., small positive incremental changes that yield compounding benefits over time – realtime analytics plays a powerful role in enabling organisations derive value in a similar way. It is because real-time analytics provides, or significantly contributes to, the information needed to identify the positive changes that drives the Kaizen principal. There are many examples where real-time analytics plays a significant role. The golden thread centres on time and cost-savings. Ultimately, by doing things in less time or at a lower cost than expected or needed, business performance is improved.", "pred_label": "__label__POS", "pred_score_pos": 0.7894099354743958} +{"content": "The module aims to introduce students to the theoretical perspectives, roles, and practical activities associated with Leadership both in contemporary organisations and in the historical context.\nStudents completing the module successfully should:\nA Describe and explain the historical development of Leadership B Recognise the activities, functions and roles related to being a leader in a variety of organisational contexts, and explain both the rationale for this and the implications for those who are ‘led’ C Compare and contrast a range of theoretical perspectives concerning Leadership D Outline and explain Leadership styles and practices, and their links to organisational and HR strategies E Discuss Leadership in relation to legal, ethical and organisational success criteria F Explain the factors affecting the ‘leader-led’ relationship, and the variety of frameworks (both formal and informal) that exist to facilitate this. G Consider the various models of Leadership that exist, and outline a range of methods for assessing Leadership in contemporary organizations.\nLecture and tutorials on a weekly basis, with case study use.", "pred_label": "__label__POS", "pred_score_pos": 0.8680789470672607} +{"content": "6 Effective Budgeting Strategies To Spend Wisely\nIntermediate\n7 mins read\n12 days ago\nTrying to stay on top of your finances can be quite a challenge when selecting the best method or strategy that works best for you. In fact, several people consider budgeting such a rigorous and challenging task because they often aren’t using the right budgeting strategy for them. Budgeting is more than simply listing out expenses and how much they may cost. There are several strategies involved in budgeting, and knowing them would enable you to select the best choice for you.\nWhat is a budgeting strategy?\nA budgeting strategy is a conscious, calculative approach to manage your funds. Several people use budgeting strategies to ensure they don’t exceed their monthly income without meeting their necessities. This is why often, a budget is considered restrictive and used when you have limited funds. However, budgeting strategies enable you to reach your financial goals, manage resources, track your expenses and cultivate a savings habit.\nBudgeting strategies aren’t limited to individuals; in fact, companies use them to manage their funds and ensure all departments within the organization have their needs met while having enough resources to invest in future opportunities and expand.\nEffective budgeting Strategies\nMany people are familiar with the traditional budgeting method, which involves making a list of your weekly and monthly expenses and how much they cost. After subtracting the cost of their expenses for the week or month from their income, the remaining funds can either be channelled to their savings or used for other miscellaneous expenses. Yet, this method isn’t practical and sustainable for everyone.\nIt is important to know other budgeting methods that have proven effective for millions across the world. These budgeting strategies include:\n1. The 50/30/20 Budget Method\nThe 50/30/20 plan is an effective budgeting technique that ensures that all your expenses are met while still attaining your savings goal. It is quite straightforward to set up and isn’t time-consuming. This makes it a popular choice for persons seeking to grow their savings and investments. The 50/30/20 plan focuses on channelling your income into three categories: essentials, wants, and savings or investments. 50% of your earnings go into meeting your essential needs; groceries, rent, bills. Healthcare, transportation. 30% of your income is spent on your wants such as dining out, hobbies. It is essentially spent at your discretion on non-essentials. The remaining 20% is left in your savings account or used for investment.\nThis strategy proves effective in managing your finances, however, doesn’t offer much information on details on exactly what your money is going into making it hard to keep track of your expenses. For instance, you know 50% of your income is going into settling bills but then you don’t know how much you spend on gas, electricity, and transportation in a month. However, it proves very effective for persons who want to budget and save without going into many details.\n2. Zero-based Budget\nThe Zero budget is known to be effective for people who want to keep track of their expenses and wish to ensure that every dime from their budget is properly dedicated to meet a need. It is effective for savings and staying in control of your finances to get out of debt by being calculative. The Zero budget ensures that you don’t exceed your income while ensuring you get the best value for your money.\nThe zero-budget is designed such that every dime is assigned to a certain budget category such as bills, savings, debt payments. The zero budget requires that you spend each month creating a detailed list of your expenses even wants such as going to a game. It accounts for your debts, savings, and investments. The idea is that once you assigned each penny in your account to an item all that should be left is zero. This helps minimize impulsive spending and although some may consider it restrictive it has proven effective for beginners who are new to budgeting.\nHere is an example of a Zero-based budget for an individual with a $1000 income.\nRent- $300\nGroceries - $100\nUtility bills (Gas, internet, electricity)- $80\nStudent loans -$125\nTransportation- $50\nEating out- $75\nClothing- $60\nSavings- $210\nRemaining balance: $0\nWith a zero-based budget, all expenses and debts are met to the best of your satisfaction and your wants are met as well while securing enough for savings and investments.\n3. The Envelope Method\nThe Envelope Method is also known as cash-based budgeting is popular among people who wish to curb impulsive spending habits. This budget strategy involves dividing your income in physical portions into different expense categories. With this method, you divide your monthly income into physical portions towards different expense categories. It involves taking a few envelopes, writing the names of each category on them such as groceries, transportation, and allocating funds to these categories.\nIt may sound outdated especially in a modern world that promotes the cashless policy but has proven effective in reducing bad spending habits. Once you have spent all the funds for gaming or eating out then you understand that you are done with spending on that category to the next budgeting period. It trains your mind to be more cautious with spending money understanding that you can’t access more funds till the next month.\nHowever, if an urgent need arises you can borrow from another category. It has proven effective for parents trying to teach their children healthy saving habits. However, the spending limits might prove too difficult for people to maintain thus prompting them to continuously borrow from other categories invalidating the budgeting strategy. Also, people who are unfamiliar with using cash for each expense might find the process tasking. An alternative might be to use budgeting apps designed like enveloping budgeting method to help you ease the process without having to withdraw your funds in cash.\n4. Value-Based Budget\nThe value-based budget focuses more on you rather than the numbers in your budget. It understands that you have wants and things you desire and believes you deserve to enjoy your money. It focuses on spending money on what you consider important. It helps you categorize your spending according to what you consider valuable. In this budgeting system, you allocate funds to meet the necessities; rent, groceries, utility bills. However, it is up to you to decide how you spend the rest of your money. The focus is then to spend money on what makes you happy like a new mobile phone, a dine-out at an expensive restaurant, or VIP tickets at a concert. It is highly personalized and focusing on meeting your needs while ensuring you get to enjoy and spoil yourself a bit with your income. It may also be considered as pay yourself first budget which ensures that you sort out all your monthly expenses first with your income. You can then decide what you with the rest of the money.\nThis budgeting strategy may not encourage savings and it is only effective for persons who are frugal, disciplined and have already cultivated a savings habit. It may also may it difficult to keep track of what you spend your money on. However, it is effective for people who prefer no restrains and are keen on meeting their monthly expenses while maintaining their lifestyle.\n5. The 60% Solution\nThe 60% formula is similar in structure to the 50/30/20 budgeting strategy but offers more flexibility. The budgeting strategy recognizes how tiresome budgeting can be and aims to achieve your financial goals while still providing you with some comfort. It involves allocating 60% of your income to what is termed committed expenses which centre on food, rent, debts, clothing, medical bills among other necessities. All your bills, even certain wants like expensive Cable TV, fall into this category. The 60% covers all the bills you have to pay every month.\nThe remaining 40% is then divided into four categories; long-term savings, short-term savings, retirement savings, and fun money with each category taking 10% of your income. An alternative for persons who have their retirement savings deducted directly from their gross is to use these funds for investments. Long-term savings cover emergency funds and funds you wish to accumulate over the years. Short-term savings are saved in a separate account and are saved up for use within a year. The remaining funds in this category at the end of the year can be added to your long-term savings. It is usually to cover up a short-term goal such as the purchase of a new car or house. Fun money covers all other expenses like gaming, eating out, purchase of collectibles among other wants.\nThis budgeting strategy is proven most effective when it is automated. It is effective for building long-term financial growth and stability.\n6. The ‘No’ Budget\nThis budgeting strategy is quite effective for persons who have already cultivated a savings habit. It involves reviewing previous months’ expenditures to ascertain how much is spent on bills and necessities over the month and when they are due. It is often most effective when automated. The goal is to ensure that you don’t spend more than you make. Once, you have reviewed your expenses and ascertained that what you spent the past months hasn’t surpassed what you make you can proceed with this budget.\nOnce you have met your necessities and saved what you consider necessary you can spend the rest of the funds on what you deem fit. This budget strategy doesn’t have much structure and may prove ineffective for persons who don’t have a healthy savings habit and makes it difficult to track expenses. However, it offers flexibility for persons keen on no restrictions in budgeting.\nConclusion\nBudgeting is an effective tool used in ensuring that you get the best value for your hard-earned money. With the right budgeting strategy in place, you can spend money comfortably without worrying about overspending and going into debt while cultivating a healthy saving habit. With the right budgeting strategy, you would be able to meet your investment goals and attain financial growth and stability.\nHowever, it is important that you aren’t mimic another person’s budget but being true to yourself when selecting a budgeting technique to attain the best result. You can attempt the different types of budgeting techniques to find out which suits you best. With the right budgeting technique financial freedom is within the grasp of your hands.\nDisclaimer: This article is meant to provide general guidance and understanding of cryptocurrency and the Blockchain network. It’s not an exhaustive list and should not be taken as financial advice. Yellow Card Academy is not responsible for your investment decisions.\nWant knowledge straight to your inbox?\nGet Top Crypto News & Updates from around the world delivered to your inbox once a week", "pred_label": "__label__POS", "pred_score_pos": 0.7796614170074463} +{"content": "Asked by: Diyana Tropschuhasked in category: General Last Updated: 17th May, 2020 What is Oxaloacetate used for? Oxaloacetateis an intermediate of the citric acid cycle, where it reacts with acetyl-CoA to form citrate, catalyzed by citrate synthase. It is also involved in gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis. Oxaloacetateis also a potent inhibitor of complex II.\nThen, how is Oxaloacetate replenished?\nRather,\noxaloacetate is formed by the carboxylation of pyruvate, in a reaction catalyzed by the biotin-dependent enzyme pyruvate carboxylase. If the energy charge is high, oxaloacetate is converted into glucose. If the energy charge is low, oxaloacetate replenishes the citric acid cycle.\nSubsequently, question is, is Oxaloacetate consumed in the citric acid cycle? With each turn of the\ncycle one molecule of acetyl-CoA is consumed for every molecule of oxaloacetate present in the mitochondrial matrix, and is never regenerated. The three steps of beta-oxidation resemble the steps that occur in the production of oxaloacetate from succinate in the TCA cycle.\nSimilarly, you may ask, what foods contain Oxaloacetate?\nOxaloacetate is in every food you eat. It's in chicken, it's in peas, it's in potatoes, it's in apples, it's in spinach.\" And they said, \"Well yes, but nobody has been selling food specifically for it's oxaloacetate content.\nHow does pyruvate become Oxaloacetate?\nPyruvate is first converted by pyruvate carboxylase to oxaloacetate (OAA) in the mitochondrion requiring hydrolysis of one molecule of ATP. However, during starvation when cytosolic NADH concentration is low and mitochrondrial NADH levels are high oxaloacetate can be used as a shuttle of reducing equivalents.", "pred_label": "__label__POS", "pred_score_pos": 0.9153112769126892} +{"content": "April 7, 2021\nNEW YORK, NY — Today, in response to the 2021 state budget, Raysa Rodriguez, associate executive director at the Citizens’ Committee for Children, a leading organization of the Family Homelessness Coalition, released the following statement:\n“We thank Governor Cuomo, Majority Leader Stewart-Cousins and Speaker Heastie for creating a rent relief program that directs billions of dollars in much needed federal aid towards keeping New Yorkers housed. These resources will protect families with children across the state from the trauma of eviction and homelessness as we begin to rebuild from this crisis. However, more must be done to ensure existing eviction prevention resources reach more New Yorkers, to provide long-term rental assistance for those who need it, and to ensure the thousands of women and children languishing in shelter are quickly moved into permanent housing with the support systems they need to reach long-term stability. Furthermore, we implore leaders in Albany to ensure the application for federal rent relief funds goes live as soon as possible so families get timely access to rent subsidies, ensuring New York’s children can grow up stably housed.”", "pred_label": "__label__POS", "pred_score_pos": 0.7357100248336792} +{"content": "Abstract\nResearch on figurative meaning in Autism Spectrum Disorder (ASD) would benefit from considering a greater variety of data types and using more diverse methods. Previous studies have predominantly applied experimental methods to investigate processing of figurative language (mostly metaphor) and have for the most part concluded that individuals with ASD have deficits in figurative language comprehension. In this study, we focus on the creation and communication of figurative meaning in discursively situated and thematically organized verbal, gestural, and pictorial data published by an autistic artist in the form of videos and comics. Across three prominent experiential themes in the data, we isolate types of conceptualizations and generalize over mappings between target and source experiences. We find that the data are rich in figurative meaning expression (e.g., metaphor and metonymy) conveyed through language, co-speech gestures, and pictures in ways that are clearly embodied (experientially based) and that reflect affordances and constraints of these modes of communication. While our case study of meaning production does not contradict previous research on figurative meaning comprehension in populations, it does indicate benefits of taking a broader and multimodal approach to figurative meaning in research on ASD.\nDetaljer\nOriginalspråk engelska Sidor (från-till) 1-33 Tidskrift Language and Cognition Volym 13 Utgåva nummer 1 Tidigt onlinedatum 2020 Status Published - 2021 Publikationskategori Forskning Peer review utförd Ja", "pred_label": "__label__POS", "pred_score_pos": 0.5249018669128418} +{"content": "Need assistance with this assignment. Included are the instructions and resources provided by the professor.\nProfessional must include Plagiarism report and be willing to do revisions if needed. Approximately 2–4 pages in length with double-spacing and 12-point Times New Roman font. FOSTER RELATIONSHIPS INSTRUCTIONS AND RESOURCES CITATION HELP https://learn.snhu.edu/d2l/le/content/854416/viewContent/14570125/View MANAGEMENT THEORIES UNIT (The Little Book of Big Management Theories) https://learning.oreilly.com/library/view/the-little-book/9781292200644/html/chapter-048.html?sso_link=yes&sso_link_from=SNHU https://learning.oreilly.com/library/view/the-little-book/9781292200644/html/chapter-051.html?sso_link=yes&sso_link_from=SNHU https://learning.oreilly.com/library/view/the-little-book/9781292200644/html/chapter-049.html?sso_link=yes&sso_link_from=SNHU https://learning.oreilly.com/library/view/the-little-book/9781292200644/html/chapter-053.html?sso_link=yes&sso_link_from=SNHU https://scholar.flatworldknowledge.com/books/7635/wrenchorgcomm_1.0-ch09_s01/read\nhttps://ebookcentral-proquest-com.ezproxy.snhu.edu/lib/snhu-ebooks/reader.action?ppg=207&docID=1635366&tm=1538747178104\nTEAMS DEVELOPMENT MODELS UNIT https://www.proquest.com/docview/1815500171?accountid=3783 https://fod-infobase-com.ezproxy.snhu.edu/p_ViewVideo.aspx?xtid=129071 https://fod-infobase-com.ezproxy.snhu.edu/p_ViewVideo.aspx?xtid=52673 https://ebookcentral-proquest-com.ezproxy.snhu.edu/lib/snhu-ebooks/reader.action?ppg=205&docID=4413730&tm=1538953957168 https://www.proquest.com/docview/1761637742?accountid=3783 https://www.wrike.com/blog/6-different-team-effectiveness-models/ MOTIVATING EMPLOYEES’ UNIT https://scholar.flatworldknowledge.com/books/31289/fwk-122425-ch05b_s01/read https://scholar.flatworldknowledge.com/books/31289/fwk-122425-ch06_s01/read GOAL ALIGNMENT UNIT https://www.proquest.com/docview/2085005480?accountid=3783 https://scholar.flatworldknowledge.com/books/31289/fwk-122425-ch06_s02/read\nhttps://ebookcentral-proquest-com.ezproxy.snhu.edu/lib/snhu-ebooks/reader.action?ppg=49&docID=4836524&tm=1538930383080\nhttps://ebookcentral-proquest-com.ezproxy.snhu.edu/lib/snhu-ebooks/reader.action?ppg=167&docID=4836524&tm=1540561743043 MANAGING DIVERSE TEAMS UNIT https://scholar.flatworldknowledge.com/books/31289/fwk-122425-ch02a_s01/read (SECTION 2.1,2.2,2.3,2.4,2.5, and 2.6) https://www.ted.com/talks/rocio_lorenzo_how_diversity_makes_teams_more_innovative?utm_campaign=tedspread&utm_medium=referral&utm_source=tedcomshare https://www.proquest.com/docview/2090614250?accountid=3783 https://www.proquest.com/docview/1690035381?accountid=3783 https://www.proquest.com/docview/213682507?accountid=3783 Scenario You work as a manager for J. Fernandez Marketing. In this role, you support team leads who will manage new teams within an organizational restructure. This will also support the continued success of the firm, as marketing representatives will be working on a variety of different project teams over a given period of time based on assignments and contracts. To prepare for the change, your manager, Jose Fernandez, has asked you to create a job aid to support team leads in developing relationships within and across teams to ensure effectiveness.\nFernandez Marketing Company Overview\nFernandez Marketing is a marketing firm located in a large metropolitan city. The firm develops and executes marketing plans for businesses and large corporations. It has experienced significant growth recently, and a new initiative to restructure the organization will enable it to develop agile and interdepartmental project teams that function more efficiently.\nCompany Goals and Vision\nAs you consider practices such as relationship mapping for maintaining goal alignment across departments and within stakeholder groups, consider how a common set of goals will help to support cross-departmental teams. Vision Develop world-class marketing campaigns that tell a captivating story Goals\nIncrease the number of marketing projects the company develops by 5% by increasing efficiencies internally\nAttract and develop talented teams to create and deploy high-quality, successful marketing campaigns\nTeam Development Needs\nUpper management has asked you to explain and recommend managerial theories and discuss team models as they relate to effectively managing teams. With the organizational restructure, most team members will be working on different teams with different team leads and management. Here are a few key points to keep in mind:\nTeams consist of an approximately 50/50 mix of “veteran” and new team members\nDiverse groups are represented across all teams Teams consist of representatives across all functional areas\nTypical Team Make-up\nWhile project needs may vary, a typical project team consists of the following people and roles. As you consider management theories and team models that should be addressed in the job aid, consider what is most appropriate based on factors such as team sizes and roles.\nTeam Lead (1)\nThe team lead supports the team in managing day-to-day tasks. He or she holds meetings and checks in with team members to measure progress. The team lead determines when additional resources and interventions are needed and provides what is needed.\nMarketing Representatives (2–4)\nMarketing representatives develop a marketing campaign plan based on the client’s provided specifications. More marketing representatives are typically added for projects that have multiple elements, such as social media, television, and international campaigns. The work is divided among the marketing representatives on the team. Digital Media Managers (1–2) Digital media managers oversee the creation of the digital media products, such as advertisements and social media posts, based on the information in the marketing campaign plan. Graphic Designers (2–4) Graphic designers create the visual elements necessary to convey the intended message of the marketing campaign. Copywriters/Editors (1–2) Copywriters/editors are responsible for copywriting and review of all content that is produced for accuracy and style.\nDirections\nYour boss, Jose, would like you to develop a job aid that will support consistency in organizational approaches, using management theories and team building models to support team leads. He asked that your job aid address the following: Management Theories: Use the information in the scenario to apply appropriate management theories to support a cohesive approach to leading teams and fostering relationships within teams and cross-departmentally. Note that managers are interested in applicable management theories and team models to influence their subordinate managers. You may describe one to two theories and models for consideration.\nDescribe relevant management theories, highlighting specific theories for supporting management in leading effective teams. Include the following in your response:\nHow will these specific management theories support the organization in fostering relationships within teams?\nHow will these specific management theories support the organization in fostering cross-departmental relationships?\nTeam Models: Use the information in the scenario to apply 1–2 appropriate team models to support a cohesive approach to leading teams and fostering relationships within teams and cross-departmentally.\nDescribe team models, highlighting specific models applicable to the organization for supporting relationships across and among teams. Include the following in your response:\nHow will these specific team models support the organization in fostering relationships within cross-functional teams?\nSupporting Team Success\nDiscuss intrinsic and extrinsic motivational factors for their influence on team effectiveness. Include the following in your response:\nHow do management theories and team models consider strategies for motivating teams?\nDiscuss the use of relationship mapping for maintaining goal alignment across departments and stakeholders\nDiscuss the strengths of team diversity for informing management approaches and enhancing strengths\nWhat to Submit\nEvery project has a deliverable or deliverables, which are the files that must be submitted before your project can be assessed. For this project, you must submit the following: Job Aid Your job aid should be approximately 2–4 pages in length with double-spacing and 12-point Times New Roman font. MGT-30147BestPracticesforDevelopingaJobAid\nAssignment status: Solved by our experts", "pred_label": "__label__POS", "pred_score_pos": 0.7624461054801941} +{"content": "Americans, including many new mothers, are returning to the workplace following pandemic shutdowns. Over 80% of U.S. mothers breastfeed their babies after giving birth, according to a 2016 study from the Centers for Disease Control. Over half of those mothers are still breastfeeding once their babies reach six months old. A complicated tapestry of federal and state laws affects employers of lactating mothers.\nThe federal Break Time for Nursing Mothers Law became effective in 2010. This law requires employers to provide covered employees with \"reasonable\" break times to express breast milk at work for up to one year after giving birth. Employers do not need to compensate their employers for time spent while away from work on these breaks. Notably, the law covers only some employees – those who are not exempt from the Fair Labor Standards Act's overtime pay requirements.\nThis law also requires that employers provide a suitable space for their lactating employees to express breast milk. Employers are not required to create a space specifically for this purpose but need to make one available for employees as needed. The law states that the space must be \"a place other than a bathroom, [...] shielded from view and free from intrusion from coworkers and the public.\" This means that any windows should be covered and the door equipped with a lock or marked with a sign. Employers need not provide a refrigerator, but they must permit employees to bring an insulated container to safely store their milk, as well as a reasonably secure place to keep the container.\nEmployers with less than 50 total employees may be eligible for an undue hardship exemption from this law's requirements if they can show that compliance would result in \"significant difficulty or expense when considered in relation to the size, financial resources, nature, or structure of the employer's business.\" But, this undue hardship is a high bar.\nTitle VII of the Civil Rights Act of 1964, as amended by the Pregnancy Discrimination Act (PDA), applies to private, state, and local government employers with 15 or more employees. The PDA prohibits employers from taking adverse employment actions against an individual because of pregnancy, childbirth, or a related medical condition (including lactation). Employers must treat all employees affected by pregnancy or a related medical condition the same as non-pregnant employees, including providing accommodations and allowing leave requests.\nIn addition to these federal requirements, at least 30 states have enacted laws to encourage or regulate workplace accommodations for lactating employees. All 50 states have also passed laws that create an affirmative right to publicly breastfeed. As workplaces begin to reopen, employers should ensure their policies and procedures comply with federal and state laws on lactation.\nThe content of this article is intended to provide a general\nguide to the subject matter. Specialist advice should be sought\nabout your specific circumstances.", "pred_label": "__label__POS", "pred_score_pos": 0.5061274766921997} +{"content": "World Bank Quick Search Show me: Public-private partnerships in urban bus systems: an analytical framework for project identification and preparation International development in focus Format: Corporate Author: World Bank Author: Alejandro Hoyos Guerrero, Abel Lopez Dodero Publisher: World Bank\nMany cities have sought to replicate the urban bus public-private partnership (PPP) structures that succeeded at the beginning of the millennium, such as those implemented in Brazil, Colombia, and Mexico. These cities improved their public transportation systems in the face of rapid urbanization, rising air pollution, and increasing road safety incidents through these PPP interventions. Examining these past international experiences, and others, Public-Private Partnerships in Urban Bus Systems: An Analytical Framework for Project Identification and Preparation first challenges the assumption that PPP structures are always the optimal approach for improving urban bus systems. The authors use relevant case studies to demonstrate that structuring such PPPs in cities in the developing world requires tailor-made interventions that respond to local contexts. The authors identify essential elements for PPP feasibility and invite readers to consider alternative solutions for achieving the desired objectives. This book presents an analytical framework that public transportation practitioners can use to support the process of identifying and preparing appropriate technical, financial, and legal structures to improve urban mobility if a PPP is the preferred solution. It follows a detailed, risk-based approach to thoroughly analyze the challenges that might be experienced by cities that pursue private participation in proposed urban bus interventions. Using specific examples, the authors thoroughly analyze the risks and the specific potential planning-stage challenges likely to be encountered and suggest strategies for practitioners to respond to the specific local contexts and the various alternative solutions. This study builds upon international experiences, predominantly in Latin America and in PPPs focused on streamlining fleet provision and operation. Finally, the book helps to identify and define bankable project structures that could respond well to local contexts and minimize risks\nExtent xvi, 174p. ISBN\n9781464816826\nSize N/A Price £32.95 Format Paperback Published 30 Jul 2021 Availability Out of stock - available to order Delivery\nDelivery options and charges", "pred_label": "__label__POS", "pred_score_pos": 0.5337985754013062} +{"content": "High-speed connectivity is crucial for 5G, Cloud and SD-WAN services; however, ordering wholesale broadband and other access and transport services remains a slow, outdated process.\nTrue SASE and network-as-a-service architecture require end-to-end automation and orchestration—service providers offering on-demand services will need to deliver fiber, broadband and off-net access services in as close to a zero-touch manner as possible. This can’t miss webinar is for those involved in the ordering of access and transport services between Service Providers. Hear from leading industry experts on new trends in this space, and how they and others are gaining a competitive advantage in the marketplace. You’ll learn best practices on how to: Streamline the cumbersome process of managing quotes and connecting with suppliers Turn quotes into orders more quickly and efficiently Determine if orders are on schedule Analyze if suppliers are complying with contracted terms Support a growing ecosystem of trading partners", "pred_label": "__label__POS", "pred_score_pos": 0.8725664019584656} +{"content": "Curr Top Med Chem. 2021 Oct 3. doi: 10.2174/1568026621666211004093647. Online ahead of print.\nABSTRACT\nMethicillin-resistant Staphylococcus aureus (MRSA), a leading cause of infections in human being and is usually associated with a multidrug-resistant profile, represents a significant health threat and public burden globally. The limited options of effective antibiotics motivate the search for novel anti-MRSA agents. Aminoglycoside antibiotics have been extensively applied in the medical field due to their desirable broad-spectrum antibacterial activity, especially for systemic infections caused by Gram-negative organisms. Recent studies demonstrated that aminoglycosides also possessed potential activity against MRSA, so aminoglycosides may be useful weapons to fight against MRSA. The present work aims to summarize the current scenario of aminoglycosides with anti-MRSA potential, covering articles published between 2010 and 2020. The structure-activity relationship and the mechanism of action are also discussed for the further rational design of novel potential drug candidates.", "pred_label": "__label__POS", "pred_score_pos": 0.596818745136261} +{"content": "In clinics, communities, and villages, thousands of health workers have been trained to safely administer DMPA-SC—and support women learning to self-inject.\nCountry partners have gained significant experience and learning about health worker training and supervision—including how to effectively begin offering a new contraceptive method within the context of informed choice. DMPA-SC training materials comprise a range of traditional and digital resources, including presentation slides, videos, an online training course, and job aids that can be customized for the varying needs of family planning training programs.\nSupportive supervision plays a critical role to ensure high-performing health workers have the appropriate knowledge, skills, and motivation in order to deliver quality family planning (FP) services and informed choice counseling. This package includes three supportive supervision tools that can be used by regional or district health teams when conducting supervision visits at health facilities that offer FP services:\nSupportive supervision checklist to assess provision of family planning counseling\nObservation checklist to assess health workers counseling clients on DMPA-SC self-injection\nRemote supervision of family planning providers (includes family planning and self-injection)\nTools #1 and #2 can be used together or separately, depending on whether or not the supervision visits include follow-up with providers recently trained to counsel clients on DMPA-SC self-injection.\nTool #3 is intended for use in situations where in-person supervision is not possible; the supervision exercise can be conducted through phone or video. This tool includes guidance and instructions for supervisors who plan to conduct supervision remotely.\nThe tools are intended to serve as guides and can be adapted for specific settings as needed. For more information, contact FPoptions@path.org.\nInstitutional Author(s): PATH, JSI, Inc.Publication date: July, 2021\n;\nGuideGuidance for using supportive supervision tools\nThe Task Sharing Strategic Planning Guide is intended to lead program managers, planners, and policymakers through a strategic process to determine if and how task sharing family planning (FP) services can be used to help achieve development goals. Task sharing is defined as the systematic redistribution of family planning services, including counseling and provision of contraceptive methods, to expand the range of health workers who can deliver services (WHO, 2017). Task sharing is a safe, effective, and efficient means to improve access to voluntary sexual and reproductive health services and reach national FP goals.\nThis training module is part of a World Health Organization series of modules on immunization training. Supportive supervision involves supervisors and health workers working together to solve problems and improve performance. The module outlines key steps and practical implementation strategies.\nThis 32-page publication outlines the GATHER model of family planning counseling, which has been successfully used for nearly two decades and is based on the elements described including tips, illustrations, techniques, technical information, and charts.\nThis checklist is a customizable tool that can be used to monitor Subcutaneous DMPA (DMPA-SC, Sayana® Press) contraceptive self-injection programs and health worker practices. The questions can be adapted as needed to align with local program designs and guidelines. To access the MS Word version of this tool in English or French, please email FPoptions@path.org.", "pred_label": "__label__POS", "pred_score_pos": 0.8558229207992554} +{"content": "From: www.fda.gov\nThe U.S. Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry titled, “Advanced Prostate Cancer: Developing Gonadotropin-Releasing Hormone Analogues.” This draft guidance provides recommendations for drug development programs to establish the effectiveness and safety of gonadotropin-releasing hormone (GnRH) analogues for treating advanced prostate cancer. Prostate cancer is one of the most common forms of cancer in American men. GnRH analogues are the primary treatment for patients with prostate cancer. Therefore, it is important to ensure industry has the most current information available for development of GnRH analogues.\nThe draft guidance outlines standardizing trial design including information regarding patient population, endpoints, chemistry, manufacturing and statistical considerations. The guidance also addresses the regulatory requirements for approval of GnRH analogues.", "pred_label": "__label__POS", "pred_score_pos": 0.5404977798461914} +{"content": "Ghanaian Social Entrepreneur Is Championing Waste Recovery And Helping Cassava Farmers Combat Post-harvest Losses\nMaxwell Deladem Xonu, in his capacity to ensure an eco-friendly environment, has built EBAPreneur. EBAPreneur is a social enterprise that focuses on two things; promoting positive impacts on climate and helping local farmers combat post-harvest losses.\nBefore EBAPreneur was established, the Ghanaian entrepreneur and his team received support from the United Nations Environment Program, Nairobi. Maxwell stated that the patrons of the program trained and equipped them with the necessary skills to produce briquettes and fabricate solar driers. After acquiring the necessary skills, the young social entrepreneur set on to build one of the innovative agricultural value chain enterprises in the country.\nFounded in 2019, EBAPreneur produces briquettes from wastes such as corn husk, cassava and potato peels, and sawdust. Additionally, the startup fabricates solar driers from locally sourced materials to help farmers reduce post-harvest losses. The solar driers create a suitable temperature for drying harvested farm produce, such as cassava, faster without any atmospheric disturbance.\nMaxwell focused on the two products because briquettes are cheap, last longer than charcoal, lessen pressure on trees, and release little to no soot into the atmosphere. Also, post-harvest loss is a major risk factor in the production of cassava which has led to the decline in figures for most farmers. They have tried to minimize the situation by providing traditional approaches to combat the deterioration, yet, they achieved nothing.\nConcerning this, Maxwell and his team have successfully mounted solar driers in two regions for its pilot phase. They have done so in Apegusu and Akotikrom in the Volta and Eastern regions respectively.\n“ 60% of Ghanaians still use firewood and charcoal for cooking due to economic challenges. 1% use electricity and below 2% use LPG. We want the statistics to change and that is what I believe EBAPreneur is championing,” Maxwell stated.\nThis month, Maxwell and his team were adjudged winners of the Israeli Green Innovation Competition, an initiative that supports sustainable green innovation initiatives by young Ghanaian startups.\nEBAPreneur was selected as the winner of the keenly contested final against four others based on the originality of their solution, social impact ability, environmental friendliness, sustainability, and ease of use.\nMaxwell received a fully-paid trip to Israel to participate in industry-related conferences, learn best practices, network, and seek potential investors to expand his existing business.", "pred_label": "__label__POS", "pred_score_pos": 0.977790117263794} +{"content": "You, God, are my God, earnestly I seek You; I thirst for You, my whole being longs for You, in a dry and parched land where there is no water. – (Psalm 63:1, NIV) God, You are my God. I am searching so hard to find You. Body and soul, I thirst for You in this dry and weary land without water. – (Psalm 63:1, ERV) O True God, You are my God, the One whom I trust. I seek You with every fiber of my being. In this dry and weary land with no water in sight, my soul is dry and longs for You. My body aches for You, for Your presence. – (Psalm 63:1, VOICE)\nThankfully, in the Pacific Northwest, the land is rarely dry and parched without water. However, all of us have seasons where we find ourselves thirsty for more. The only One who can truly satisfy is God. He brings strength and rest in our weariness, peace in our chaos, and love where it seems to be lacking. His timing is perfect, and He knows our needs best. Normally, today would be the beginning of the home stretch of a long week, yet tomorrow, just in time, is a day that will provide much needed rest. It is far easier to find the strength and resolve to rise and prepare for the day when it is the final work day of the week. I know that the feeling is similar among educators everywhere, as this has been a long and exhausting start to the school year. It is amazing to have kids back in classrooms, yet I am experiencing and can see it on the faces of my colleagues, weighty weariness. As I continue to seek the Lord to fill and renew me, it is my prayer that the extra day of rest will bring refreshment and new resolve for staff and students alike. May we choose to trust in the Lord, who is our strength and supply, even in the dry and weary spaces.\nWhen weariness comes, And reserves run dry; The Lord is faithful, In love, He’ll reply. Each time we ask Him, With grace, He comes near; Grants strength in weakness, And quiets our fear. His strength is plenty, His grace provides rest; His love overwhelms, And His care is best.\nDear Heavenly Father, thank You that we can come to You when we are weary and parched, and You are faithful to meet us where we are and provide what we need. Thank You that You love us best, and care for us through every trial and triumph. Forgive us for not seeking You in our lack. Teach us to trust You more, as You are our Provider. Show us how to love those around us in ways that bring strength in weariness and grace and goodness where it is lacking. May many come into a lasting relationship with You. Be glorified O God, as we seek You to satisfy our lack and bring peace in our weariness. Amen.\nGrace and peace to you from God our Father and the Lord Jesus Christ. – 1 Corinthians 1:3", "pred_label": "__label__POS", "pred_score_pos": 0.5709607601165771} +{"content": "Posted: Tuesday, January 19, 2021. 9:21 am CST.\nThis morning, UNICEF Belize will host a handover ceremony for recreational kits to Belize City Council. By BBN Staff:\nChild Friendly Spaces (CFSs) are widely used in emergencies as a first response to children’s needs and an entry point for working with affected communities.\n“Because CFSs can be established quickly and respond to children’s rights to protection, psychosocial well‐being, and non‐formal education, CFSs are typically used as temporary supports that contribute to the care and protection of children in emergencies,” UNICEF noted.\nHowever, they are used also as transitional structures that serve as a bridge to early recovery and long-term supports for vulnerable children.\nUNICEF noted that it has found that CFS contribute to mitigating protection risks after and emergency, risks such as human trafficking, child labour, separation from families.\nIn Belize, CEMO and the Belize Red Cross have been partnering with UNICEF Belize to establish and implement Child Friendly Spaces. This has led to the training of 30 volunteers countrywide.\nUNICEF Belize is now providing the recreation kits to prepare these partners to implement and deploy support for CFS in Belize.\n“UNICEF remains excited about the partnership with emergency response partners such as CEMO and Red Cross. The initiative, grounded in a holistic rights-based approach, constituted an integrated program that could guarantee minimum standards with regard to essential protection and services to children in times of crisis,” a statement from UNICEF expressed.\nDeputy Mayor, Michael Norales and Director General of the Belize Red Cross will be receiving the kits.\nАdvеrtіѕе wіth thе most visited news site in Веlіzе ~ Wе оffеr fullу сuѕtоmіzаblе аnd flехіblе dіgіtаl mаrkеtіng расkаgеѕ. Yоur соntеnt іѕ dеlіvеrеd іnѕtаntlу tо thоuѕаndѕ оf uѕеrѕ іn Веlіzе аnd аbrоаd! Соntасt uѕ аt [email protected] оr саll uѕ аt 501-601-0315.\n© 2021, BreakingBelizeNews.com.\nThis article is the copyrighted property of Breaking Belize News. Written permission must be obtained before reprint in online or print media. REPRINTING CONTENT WITHOUT PERMISSION AND/OR PAYMENT IS THEFT AND PUNISHABLE BY LAW.", "pred_label": "__label__POS", "pred_score_pos": 0.872617244720459} +{"content": "Arthritis\nInflammation of a joint producing stiffness, warmth, swelling, redness and pain. Types of arthritis include osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudo-gout.\nPotential treatments include: patient specific interventions including postural realignment therapy, insole treatment, knee bracing, wedged orthoses, walking aids, manual therapy, weight loss, home-based exercises, strength training, knee stability training, Class IV laser, electrical stimulation, ultrasound, and vibration therapy with passive motion.", "pred_label": "__label__POS", "pred_score_pos": 0.7278691530227661} +{"content": "Trajectories of Advanced Math Taking for Low-income Students of Color in Middle and High School Courtney Ricciardi Major Professor: Adam Winsler, PhD, Department of Psychology Committee Members: Olga Kornienko, Toya Frank\nOnline Location, Virtual - https://us02web.zoom.us/j/87435083960?pwd=WUpCdThkNmJGTFAxVUs5TDdqcWdyZz09\nApril 16, 2021, 10:00 AM to 12:00 PM Abstract:\nDifferential access to and enrollment in advanced mathematics for historically underrepresented groups is a pervasive problem in education. Access to advanced coursework is associated with positive postsecondary outcomes including college acceptance, retention, graduation and more. However, current research examining this problem primarily focuses on achievement in this domain rather than access. This necessitates an examination of who is accessing advanced coursework and what differentiates the course trajectories students follow across middle and high school.\nThis dissertation sought to explore what pathways students were following in advanced math coursework across middle and high school and how demographics, school readiness, and prior academic achievement related to pathway followed. These questions were answered using a large-scale (N = 18,841), majority Latinx (57.6% Latinx, 35.5% Black, 6.1% White/Other, and .6% Asian/Pacific Islander) and low-income sample (77.3% on free or reduced lunch in 6th grade) from the Miami School Readiness Project. Latent class analysis (LCA) was used to categorize students into 6 classes, which in this study represented the commonly followed pathways of advanced math taking. The 6 class pathways which emerged were Never Advanced (standard math in middle and high school), Early Advanced Tryer (advanced in middle school, standard in high school), Late Honors Tryer (standard in middle school, honors in high school), Consistently Mid-level Advanced (advanced in middle school, honors in high school), Primarily Advanced with some College Level (advanced in middle school, standard with some college level in high school), and Most/Earliest Advanced (honors in middle school, standard and some college level in high school).\nFollowing this, multinomial logistic regression was used to connect individual demographics, school readiness, and prior academic achievement to the likelihood of being assigned to a particular class trajectory. Results revealed that prior academic performance was most strongly related to advanced math pathway assignment, but even when controlling for this variance, gender, special education status, and cognitive and fine motor skills at age 4 also impacted what math pathway a student was likely to follow in middle and high school. Race/ethnicity was a significant differentiator when comparing the two most advanced pathways. These findings highlight the importance of early school readiness skills and demonstrate how early opportunity gaps impact later student outcomes. Furthermore, this project illustrates how tailored intervention and supports are necessary to ensure equitable access to coursework and programming which expands a student’s opportunities and chances for postsecondary success.", "pred_label": "__label__POS", "pred_score_pos": 0.8159598708152771} +{"content": "São Tomé and Príncipe The insular position of São Tomé and Príncipe has not prevented the development of a wide range of agricultural crops. Surprisingly, though, the Chocolate Island, as it is often called, has presently only 45,8% of its land under cultivation.\nThe inhabitants of São Tomé and Príncipe like to cook with palm oil, however, local production is insufficient to meet domestic demand. This has resulted in overpriced palm oil, forcing the population to reduce its daily consumption.", "pred_label": "__label__POS", "pred_score_pos": 0.6026421785354614} +{"content": "Department of Chemical Engineering and Biotechnology, Institute of Biotechnology, University of Cambridge, Cambridge, United Kingdom.\nSpores of Bacillus megaterium QM B1551 germinate rapidly when exposed to a number of single-trigger germinant compounds, including glucose, proline, leucine, and certain inorganic salts. However, spores of strain PV361, a plasmidless QM B1551 derivative that lacks the GerU germinant receptor (GR) responsible for mediating germination in response to single-trigger compounds, can germinate efficiently when incubated in nutritionally rich media, presumably via activation of additional germinant receptors. In this work, we have identified five chromosomally encoded GRs and attempted to characterize, by mutational analysis, germinant recognition profiles associated with the respective receptors in strain PV361. Of strains engineered with single GR insertion-deletions, only GerK-null spores displayed significant defective germination phenotypes when incubated in 5% (wt/vol) beef extract or plated on rich solid medium. Cumulative decreases in viability were observed in GerK-null spores that also lacked GerA or GerA2, indicating that these GRs, which exerted little effect on spore germination when disrupted individually, have a degree of functionality. Unexpectedly, an efficient germination response to combinations of germinants was restored in GerA(+) spores, which lack all other functional GRs, providing evidence for negative cooperativity between some GRs within the spore. Tetrazolium-based germinative assays conducted with purified spores indicated that these newly characterized B. megaterium GRs are cognate for a wide and chemically diverse range of germinant molecules, but unlike GerU, can only be induced to trigger germination when stimulated by at least two different germinants.\nSrishti Gupta, Fatma Isik Ustok, Christian L Johnson, David M D Bailey, Christopher R Lowe, Graham Christie.Investigating the functional hierarchy of Bacillus megaterium PV361 spore germinant receptors.\nJournal of bacteriology.2013 Jul;195(13):3045-53\nPMID:\n23625848", "pred_label": "__label__POS", "pred_score_pos": 0.6924525499343872} +{"content": "Security Guards are an essential part of Screening for Covid-19.\nThey can contribute to a safer environment by reducing the number of accidents and injuries that could have been caused by other people entering the facility. They can also serve as the first line of defense against any potential threats or attacks, preventing them from reaching their intended target. They are trained professionals who know how to handle any situation thrown at them, whether it be violence, theft, or anything else that could potentially happen on the job. Security Guards have been proven to reduce accidents and incidents at Screening Facilities, making them an invaluable part of Security for Covid-19.\nSecurity Guards can handle any situation thrown their way during Security Screenings. They are trained professionals who know how to react safely when situations arise. Security guards also serve as a deterrent to criminals and thieves, meaning Security Screenings are less likely to have incidents or accidents occur. Security Guards for Screening Covid-19 are invaluable due to their ability to handle any situation that could potentially happen during Screening Procedures.", "pred_label": "__label__POS", "pred_score_pos": 0.9984599351882935} +{"content": "Qualifications Research Interests\nMy group’s research is at the forefront of the emerging field of conservation physiology, which explores the responses of organisms to anthropogenic threats. We integrate a wide range of tools (respirometry, performance testing, cardiovascular physiology, biochemical assays, field-monitoring, niche-modelling and meta-analyses) to determine the eco-physiological constraints dictated by current conditions and future environmental change.\nCurrently, our research is focused on how fish, reptiles and amphibians respond to a multivariate set of changes in their habitat. To survive, species must navigate a milieu of stressors (e.g. climate warming, contamination, acidification, hypoxia, invasive species, etc.) and stressors often interact in complex ways. Global climate change is expected to exacerbate the multitude of stressors organisms face, particularly for aquatic species in higher latitude regions, such as New Zealand. Essential to our ability to generate robust predictions of how New Zealand’s fauna will fare in the face of climate warming, is an understanding of the physiological mechanisms these organisms use to respond to multiple threats. Our research explores how exposure to stressors modulates a species’ capacity to cope with climate warming. Specifically, we explore the impact of stressors on thermal acclimation capacity, heat tolerance, and thermal reaction norms of locomotor performance, metabolism and lower-level physiological functions. For more information about my group’s research and opportunities visit our website (www.rodgerslab.com). Recent Publications Pillet M., Castaldo G., Rodgers EM., Poleksić V., Rašković B., Bervoets L., Blust R. and De Boeck G. (2021) Physiological performance of common carp (Cyprinus carpio, L., 1758) exposed to a sublethal copper/zinc/cadmium mixture.Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 242 http://dx.doi.org/10.1016/j.cbpc.2020.108954. Rodgers EM. and Franklin CE. (2021) Aerobic scope and climate warming: Testing the “plastic floors and concrete ceilings” hypothesis in the estuarine crocodile (Crocodylus porosus).Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 335(1): 108-117. http://dx.doi.org/10.1002/jez.2412. Rodgers EM. and Gomez Isaza DF. (2021) Harnessing the potential of cross-protection stressor interactions for conservation: a review.Conservation Physiology 9(1) http://dx.doi.org/10.1093/conphys/coab037. Rodgers EM., Franklin CE. and Noble DWA. (2021) Diving in hot water: a meta-analytic review of how diving vertebrate ectotherms will fare in a warmer world.Journal of Experimental Biology 224 http://dx.doi.org/10.1242/jeb.228213. Rodgers EM., Opinion AGR., Gomez Isaza DF., Rašković B., Poleksić V. and De Boeck G. (2021) Double whammy: Nitrate pollution heightens susceptibility to both hypoxia and heat in a freshwater salmonid.Science of the Total Environment 765 http://dx.doi.org/10.1016/j.scitotenv.2020.142777.", "pred_label": "__label__POS", "pred_score_pos": 0.617082953453064} +{"content": "If you or your child was diagnosed with a vascular malformation, having a pediatric plastic surgeon on your team is critical to obtaining a safe, aesthetic result. Whether you are dealing with a hemangioma, vascular malformation, or lymphatic malformation, Dr. Mark Fisher offers a high level of fellowship training, enabling him to successfully address even the most complicated cases.\nRecovering and Maintaining Your Results\nDepending on the size of the vascular malformation, the patient’s age, and the type surgery, you or your child may go home after surgery or stay in the hospital overnight for observation. Regardless of the method used to address your issue, Dr. Fisher and his staff will closely monitor you and schedule follow-up appointments to make sure you are healing well.\nIf you or your child are faced with vascular malformations, Dr. Fisher and his talented team are ready to help. These issues are often best addressed as early as possible, and you are encouraged to bring your child to Dr. Mark Fisher if you suspect or know that a vascular malformations might be present. As a fellowship-trained pediatric plastic surgeon, Dr. Fisher will work with you to address your concerns and obtain the best possible result.", "pred_label": "__label__POS", "pred_score_pos": 0.6020228862762451} +{"content": "The West Midlands Academic Health Science Network (WMAHSN) has released its annual impact report, sharing statistics and case studies to highlight some incredible healthcare innovations that have come out of the West Midlands during what has been the most challenging year in history for the UK’s health and care system.\n2020 was a year of transformation for the WMAHSN with key achievements including 671 sites using innovations across the West Midlands, 500 patients benefitting from a new Emergency Laparotomy pathway and 15,906 being diagnosed with heart conditions and bringing in over £4 million worth of investment.\nWhile supporting on the UK’s efforts against the pandemic meant that many of the network’s programmes and priorities needed to be adapted or realigned over the past 12 months, the WMAHSN has remained committed to improving the region’s health and wealth, working more closely with partners than ever before, and identifying three key areas to transform patient care: improving population health, transforming patient safety through innovation, and enabling economic growth.\nKey innovations highlighted in the report are:\n· Guidance on how to safely switch warfarin to DOAC therapy in patients that are prescribed long-term anticoagulation medication. The WMAHSN supported local teams across the West Midlands in identifying patients who needed to switch medication and make sure they could do so safely. This led to an increase in confidence of anticoagulation nurses and pharmacy professionals and reduced the burden on local anticoagulation services by switching to drugs which can be more easily prescribed and managed long-term.\n· Transfer of care around medicines (TCAM) to Care Homes through implementing the direct referral of discharged residents to pharmacy teams which provide services to care homes. This resulted in direct support for care home residents, enabling them to receive accurate and timely administration of medicines after discharge from hospital throughout the pandemic, while pharmacy teams were unable to provide home-based medicines optimisation that patients needed.\n· Supporting on the England-wide implementation and adoption of HeartFlow, a non-invasive, cardiac test for stable symptomatic patients with coronary heart disease. One of the main benefits of using HeartFlow is that it allows Doctors to get more information about a patient’s condition quicker which helps with more efficient clinical decision making.\n· Facilitating the development of the Maxi-Magni Card, a handheld magnifier lens and safe solution which enables staff wearing PPE to read small print, without the need for glasses, helping to make life easier on the front line.\nThe impact report demonstrates the WMAHSN’s ability to respond rapidly in the most challenging of times, making a real difference for patients and service users across the West Midlands.\nFor the remainder of 2021 and going into 2022, the WMAHSN is focusing on strengthening relationships with regional partners and focusing efforts on developing programmes for key themes such as cardiovascular disease prevention, mental health resilience, remote monitoring, and digital transformation, aiming to deliver significant improvements to patient outcomes and economic growth for the region.\nTony Davis, Director of Innovation & Commercial at the WMAHSN, said: “We are confident that the WMAHSN will continue to positively impact on the health and wellbeing of patients and populations at a local, regional and national level, as we emerge from what has been a challenging year for all and step forward into what could be the most innovative period the sector has ever seen.”", "pred_label": "__label__POS", "pred_score_pos": 0.5792331695556641} +{"content": "World InsurTech Report 2021\nThe World InsurTech Report 2021 from Capgemini and Efma explores the impact of exponential InsurTech growth and customer adoption on the insurance industry. Discover how insurers address this trend and should prepare for two scenarios we predict in the InsurTech era.\nWorld InsurTech Report 2021 Online Session\nJoin us on September 30, 2021 at 14.00 – 15.00 CET | 8.00 – 9.00 EDT for an exclusive presentation on the World InsurTech Report 2021. Denise Garth, Chief Strategy Officer at Majesco, and Danilo Raponi, Group Head of Innovation at Generali, will join Capgemini Insurance team to discuss the future of the insurance industry in the InsurTech era.\nAccelerated demand for insurance protection\nCOVID-19 accelerated demand for insurance protection. But, in a departure from the past, policyholders now seek coverage from various non-traditional players, including InsurTechs and BigTechs. Policyholders are gravitating towards insurers that offer better “CARE,” where Convenience, Advice, and Reach are at the heart of designing and evaluating the effectiveness of their customer journey.\nIncreased InsurTechs presence\nTech giants and InsurTechs have secured unprecedented access to capital allocation from investors and are bolstering their digital capabilities, increasing their lead as innovation frontrunners to deliver the CARE equation — customer Convenience, Advice, and Reach, unlock analytics at scale and enhance customer engagement. InsurTech full carriers are transitioning from competitors to insurance incumbents, while InsurTech enablers enjoy healthy growth through collaboration at scale with established insurers.\nReach - critical insurance differentiator\nAs policyholder expectations evolve, InsurTechs are leveraging investor capital to create a reliable data and analytics foundation and maximize the benefits of AI/IoT solutions and API/open insurance enhancements to enrich their CARE equation delivery, with a focus on Convenience and Reach.\nThe new insurance value chain\nTo navigate today’s dynamic environment, Insurers are shifting from “doing digital” to “being digital.” The insurance value chain is evolving its monolithic, siloed approach to data and CX to become a modular and specialized value chain featuring harmonized customer experience. The new insurance value chain will feature two primary scenarios: insurance embedded as a value add within third-party ecosystems, and insurance with added value at the core of complex offerings.", "pred_label": "__label__POS", "pred_score_pos": 0.9902322888374329} +{"content": "Abstract : For over 40 years, public surveys have been an essential tool for informing decisions about library offerings. While the humanities and social sciences have provided them with the necessary scientific support, marketing now gives them the backing of a performance that is changing the way the public and its practices are viewed. We have entered an era of demand that makes audience segmentation a key to winning and retaining audiences. Consequently, the ideals of efficiency, quality and satisfaction are emerging in public surveys, as they are in the public service as a whole. The survey then becomes a tool for the State to evaluate its administrations. This transformation appears to many as a constraint. However, institutions are taking it on board on their own initiative. They see it as a way for the public to legitimize their actions and their missions with the supervisory authorities, which are increasingly making budget cuts. In these surveys, recourse to the vague figure of the non-public, sometimes familiar, sometimes distant from the world of libraries, is multiplying. It bears witness, following a feeling of failure with regard to cultural democratization, to a sometimes timid pragmatism. The ways of designating, categorizing, and archetyping the non-public and public imply a hierarchization that informs representations of the public and its practices. The confrontation between a dream public and the public observed by the survey invites reflection on new library models: idea store, library as a third place, learning center.", "pred_label": "__label__POS", "pred_score_pos": 0.8028475046157837} +{"content": "Vitamina D\nQuick test using capillary blood to detect vitamin D deficiency. If the results indicate a lack of it, vitamin D supplements would be advisable for protection from diseases resulting from its deficiency, such as osteoporosis. This vitamin also boosts the immune system, thereby achieving a better quality of life during old age.", "pred_label": "__label__POS", "pred_score_pos": 0.9960466623306274} +{"content": "Abstract\nGiven the preponderance of corporate social responsibility initiatives across the corporate landscape and the correspondingly escalating demand for volunteers who participate in these initiatives, a need exists to better understand how to effectively motivate their voluntary engagement with tasks. Against this backdrop, this study argues the need to enhance their volunteer work meanings. We hypothesize that pride in volunteer work and volunteering as a calling are determinants of perceptions of the meaningfulness of volunteer work. In addition, we reveal that an organization's social responsibility climate (SRC) is a key moderator in these relationships. Interestingly, an SRC is a double-edged sword such that it strengthens the relationship between meaning and pride, yet weakens the relationship between meaning and calling. Findings are discussed, along with managerial implications and future research directions.\nScopus Subject Areas Business and International Management Business, Management and Accounting(all) Arts and Humanities (miscellaneous) Economics and Econometrics Law User-Defined Keywords Calling Climate Corporate social responsibility Employee volunteerism Pride Volunteer work meaning", "pred_label": "__label__POS", "pred_score_pos": 0.6239484548568726} +{"content": "Salisbury District Hospital is saving approximately 10% of its steam consumption following the installation of steam traps. The GEM venturi orifice traps from Thermal Energy International are helping the hospital to meet the Government's mandatory targets to reduce CO\n2 emissions by 10% by 2015. In 2009, the hospital's average steam consumption was around 295 tonnes a month, with the lowest figure recorded at 282 tonnes a month. Following the installation of 70 GEM traps, the average consumption has been reduced to 265 tonnes a month, with the lowest monthly figure dropping to 252 tonnes. Savings in energy alone will enable the hospital to receive payback on the installation in 18 months. George Atkinson, hospital spokesman, said: \"Obviously our initial carbon reduction targets were very much in line with those set out by the NHS as a whole, but we are now aiming to go further than we are actually required to do via a whole range of measures.\"", "pred_label": "__label__POS", "pred_score_pos": 0.5870797634124756} +{"content": "Turmeric is widely used to encourage soundness, and helps to support your horse's suppleness and freedom of movement. This popular nutrient is often fed to manage lumps and bumps on the skin, and contains Curcumin, which has multiple health supporting properties including antioxidants that neutralise free radicals. This supplement contains Black pepper extract, clinically proven to enhance absorption.", "pred_label": "__label__POS", "pred_score_pos": 1.0000091791152954} +{"content": "Takeaway\nWord-finding difficulty is a common problem in people with early multiple sclerosis and is linked to thinning of the left parietal cortex.\nWhy this matters\nThese findings add to the growing evidence that prominent disease-related parietal atrophy that is linked to impaired language ability is a more common problem in multiple sclerosis than previously recognized.", "pred_label": "__label__POS", "pred_score_pos": 0.9996355175971985} +{"content": "There are tons of insurance available to cater for different unexpected happenings in our lives. While we cannot prevent the unexpected from happening, insurance policies protect us when it happens. Generally, insurance is designed to safeguard us financially should certain incidents occur. It can be a hassle picking what insurance is beneficial to you even though most …", "pred_label": "__label__POS", "pred_score_pos": 0.7537460327148438} +{"content": "Each of the carrier’s three states (ID, NC and TN) have their own respective policies for these CPT codes including diagnosis requirements (see attached links). The most significant issue as far as billing of these services came about with the 2002 change in the CPT codes-especially for trigger point injections. Prior to January 1, 2002, each trigger point injected could be billed using CPT code 20550. After January 1, 2002, billing of trigger points switched from per injection to single or multiple injections per number of muscles (CPT code 20552 for single or multiple injections of one or two muscles vs. CPT code 20553 for single or multiple injections of three or more muscles). Also revised were codes for single or multiple injections tendon sheath or ligament (CPT code 20550) and tendon origin/insertion (CPT code 20551).\nSince that time, we have noted that some providers who had been billing multiple trigger point injections along the spine have now moved to billing for multiple tendon origin/insertion codes – same locations/same beneficiaries (previously treated with trigger point injections). For these injections of tendon sheaths/origins/insertions to be medically necessary, there must be an inflammatory process in a given tendon (tendonitis) or tendon sheath tenosynovitis). Unless there is a systemic underlying illness (autoimmune or the like), the inflammation of multiple tendons, tendon sheaths, and muscle insertions – especially along the spine – should be extraordinarily rare.", "pred_label": "__label__POS", "pred_score_pos": 0.7823963761329651} +{"content": "Alone and discouraged, I stared at my computer screen. I was frustrated by the way my life had turned out. I’d worked hard to hold onto remnants of hope for my marriage, but each day that summer I could feel it slipping through my fingers. I felt so alone. God was still there, I knew, but I longed for people who would talk back. Late at night, I wished I could communicate with someone who might understand my questions and respond with compassion. My heart ached with the pain of rejection. I felt so ashamed when I faced friends who knew us as a couple. It seemed like my world was falling apart. I needed encouragement. So here I was, seriously considering going into a chat room.\nAs I stared at my screen, I wondered.\nWould there be people who were safe? Would I be able to connect with others who would remind me of what I’d been taught as a child — that God loved me even then, that he’d not given up on me? Would I find friendship or face rejection because of my journey? Perhaps I would remain silent; I didn’t have to share my pain. I had heard the online world was a strange one, and I’d never seen a chat room. Cautiously, I clicked on the button inviting me to chat. Welcome to chat\n“Welcome to the room, we’re glad to have you! How’d you find our chat room?” someone asked. Soon I was welcomed not only to the chat room, but into some amazing relationships with women who cared.\nOver the next several weeks\nI began to share my journey. Here were ladies who knew and loved God. They knew his compassion toward the broken-hearted and were willing to listen to my pain. Like salve on an open wound, their care brought comfort to a wounded heart. I didn’t know it that night, but they would continue to build into my life over the next several years. They took time to share the hope that they’d found as they too had faced the unexpected. We spent time in prayer together as I faced a healing journey, one not of isolation but of renewed community. As I opened my heart to new friends, I found a place where I could be real with my hopes, dreams, questions, and disappointments. These long-distance friends reminded me that God would never turn his back on me. He would keep his promises. Over and over they reminded me that his plans for me were good plans, ones full of hope and purpose. With their support, I began to reach out to others who were hurting and to share the way God was working in my own life with women who faced similar challenges. God had not set me aside\nIn time I realized that life was not over. God had not rejected me nor set me aside. I had an opportunity to reach out to others. I could help.\nThe chat room became a place of hope and excitement as I saw God actively at work in my own life and the lives of others! As I opened my heart toward others, my own life was changed.\nEvery week I would me visitors from around the world. Some came with the pain of a broken relationship, a shattered dream, or a difficult question. Others brought with them the lessons that they’de learned on their own journey as well as gifts of hope, refreshment, and friendship. Each visitor came with a story and a heart that is seeking. The search may be for a friend, for someone to listen and understand, for advice, for new direction, or an affirmation that God still cares.\nI was thrilled as I saw uplifting friendships develop in the chat rooms. As we shared our lives and hearts with one another, many of us saw growth and change! I thank God for the way he used online friendships and discussions to restore hope in my life. For those who reached out to me, I cannot thank you enough. My life has been touched and changed.\nHave you ever wondered what kind of help you might find online? Although chat rooms are no longer as possible as they once where, thelife.com offers an online mentoring service that is free and confidential. If you would like to connect with a caring and compassionate Christian willing to join you in your journey, why not fill in the form below? Online mentoring might be just what you’ve been looking for.", "pred_label": "__label__POS", "pred_score_pos": 0.6525905728340149} +{"content": "Access to quality education for all children\nThe REAL Centre undertakes research across a range of contexts aimed at understanding and improving access to quality education for all children. Below is a summary of ongoing REAL Centre research projects.\nThis research project aims to understand whether, and how, school accountability for learning can be improved from the grassroots. In order to address this objective, we use the case of a community-based intervention in rural India, which aims to engage with local school actors (teachers, headteachers, administrators and school management committees) and provide them with knowledge and resources to implement activities in line with the goal of improving children’s foundational learning in the classroom.\nThis project explores the experiences and transitions of out-of-school girls and boys in the Complementary Basic Education (CBE) programme in Northern Ghana. It aims to assess changes in literacy and numeracy as a result of the CBE programme, including once these children continue to primary school.\nThis two-year project seeks to conduct a rigorous, mixed-method evaluation of Ghana's Free Senior High School Policy, focusing on 1) equitable access, 2) maintaining quality, and 3) sustainable implementation. In doing so, it seeks to draw lessons for policymakers in Ghana as well as other countries that are considering the abolition of secondary school fees.\nThis research aims to provide an evidence base on what works to support marginalised girls’ secondary education, with a focus on CAMFED’s programmes in Tanzania. In particular, analysis of the cost of sending a marginalised girl through secondary school and improving her learning will be undertaken. This aims to inform targeted financing mechanisms that ensure that no girl is left behind, in the drive for quality education for all.\nThe Impact Initiative for International Development Research seeks to increase the uptake and impact of research from the Joint Fund for Poverty Alleviation Research and the Raising Learning Outcomes in Education Systems Research Programme. The approach aims to connect policymakers and practitioners with world-class social science research, maximising the uptake and impact of research.\nAs part of the Research for Improving Systems of Education (RISE) programme, this five-year research project in Ethiopia aims to examine whether and how a large package of national reforms works to improve equitable learning in one of the world’s poorest and most diverse countries.\nAs learning partners for the Mastercard Foundation’s Leaders in Teaching Initiative in Rwanda, the REAL Centre and Laterite are collaborating to develop robust evidence on how the initiative is working overall to improve the quality of teaching and student learning in secondary schools, particularly for those most at risk of not learning.\nThis project focuses on developing an online database that catalogues policy-relevant education research conducted by researchers and institutions in sub-Saharan Africa. Through reviewing and synthesising this research, the aim is to increase its visibility and accessibility.\nFocusing on India and Pakistan, this project aims to identify which aspects of teaching are most important for improving all children's learning, and so inform governments on the strategies needed to support children who face multiple disadvantages. The research pays particular attention to children with disabilities, who are most likely to be excluded from learning.", "pred_label": "__label__POS", "pred_score_pos": 0.7501736879348755} +{"content": "Database search is coming soon. In the meantime, use the following categories to explore the database resources: Ontario\nThe town of Innisfil in Ontario, Canada has partnered with Uber in place of public transit. Low density development drove the town to choose subsidizing Uber over creating a public transit system due to the perceived cost of both. However, the amount Innisfil spent subsidizing Uber rides has already exceeded the amount they estimated it would cost to create a public transit system. Experts question the partnership, citing environmental and economic problems.\nUrban innovations company Sidewalk Labs and the Canadian government announced a partnership Tuesday to develop 750 acres along Toronto’s waterfront into what they envision as a high-tech living laboratory for solving urban problems. It would be the largest urban redevelopment project in North America.\nIn working with Waterfront Toronto, the public entity that owns the land, to develop Quayside, Sidewalk Labs would reimagine urban life in five dimensions—housing, energy, mobility, social services, and shared public spaces—with an aim to “serve as a model for sustainable neighborhoods” around the world.\nThis paper introduces Metrolinx’s recently released Mobility Hub Guidelines and highlights two key aspects of the document: the importance of classifying the current and planned urban context and transportation function at a mobility hub, and methods to overcome challenges in achieving both transport and placemaking roles.\nThe researcher examined six jurisdictions: three in Canada and in from the United States. In helping frame the issue for B.C. and—more specifically— the Vancouver metropolitan area context, the researcher conducted primary research to understand the accessibility challenges in the regional context and to help frame the topic of accessibility within the for-hire sector.\nSee something that should be here that isn't? Have a suggestion to make?", "pred_label": "__label__POS", "pred_score_pos": 0.6273579597473145} +{"content": "By Tina Bellon\nOct 14 (Reuters) - The performance of advanced driver-assistance technology used to help vehicles automatically brake and stay in lanes is significantly reduced by moderate and heavy rain, a study by the American Automobile Association showed on Thursday.\nResearchers at AAA, a federation of North American motor clubs, found that vehicles' auto emergency braking systems, in several instances during simulated rainfall, no longer recognized stopped vehicles ahead and that vehicles' lane-keeping systems performed considerably worse.\nThat could lead to dangerous situations if drivers rely too heavily on the systems, whose performance is typically evaluated in ideal conditions, the researchers said.\n\"The reality is people aren't always driving around in perfect, sunny weather, so we must expand testing and take into consideration things people actually contend with in their day-to-day driving,\" Greg Brannon, AAA's director of automotive engineering and industry relations, said in a statement.\nAdvanced driver-assistance systems, or ADAS, are becoming more common in newer vehicles. They do not offer autonomous driving, but can automate limited driving tasks.\nAuto emergency braking is increasingly provided as a standard feature in new cars and has shown to significantly reduce rear-end crashes in tests by insurance groups.\nIn the AAA study, no test car crashed into a stopped vehicle under ideal conditions. But during simulated rainfall, 17% of test runs resulted in crashes at speeds of 25 mph (40 km/h), increasing to 33% at speeds of 35 mph (56 km/h).\nThe pavement during the rain tests was dry and researchers noted wet roads could result in even higher crash rates.\nVehicles equipped with lane-keeping technology crossed lane markers 37% of the time during ideal conditions in the AAA test, but that rate jumped to 69% once rain was added.\nThe group tested a 2020 Buick Enclave Avenir, a 2020 Hyundai Santa Fe, a 2020 Toyota RAV4 and a 2020 Volkswagen Tiguan.\n(Reporting by Tina Bellon Editing by Bernadette Baum)", "pred_label": "__label__POS", "pred_score_pos": 0.8753399848937988} +{"content": "The\nFlorida standard residential lease agreement is a contract between a landlord and tenant that authorizes the leasing of residential property for a fixed term. Standard residential leases are typically one (1) year agreements that can be renewed or extended if the parties so desire. In the agreement, the tenant is assigned responsibilities including their financial commitments and property maintenance obligations. Some landlords may require a security deposit or an advance rent payment prior to the initial date of occupancy. Rental Laws – Title 6, Ch. 83, Part 2 (Residential Tenancies) Handbook (Guide) – Landlord & Tenant Handbook\nContents Maximum (§ 83.49) – Not mentioned in state statutes. Returning (§ 83.49(3)(a)) – Fifteen (15) days\nUnless stated otherwise in the rental agreement, the tenant must pay rent at the start of each rent payment period (§ 83.46(1)).\nAt or before the start of the tenancy, the name and address of the landlord or person authorized to receive notices and demands on the landlord’s behalf must be provided to the tenant.\nThe landlord must provide this disclosure if the dwelling was built before 1978.\nAll tenants must be provided with a radon gas disclosure which includes specific language in the state statute.\nLandlords with more than five (5) individual dwelling units must give tenants written notice regarding their security deposit. The notice must include all information stated in Subsection (2) of Section 83.49 of the Florida statutes.", "pred_label": "__label__POS", "pred_score_pos": 0.9640191197395325} +{"content": "Electrical Engineering and Systems Science > Image and Video Processing Title:Mixed-supervised segmentation: Confidence maximization helps knowledge distillationDownload PDF Abstract: Despite achieving promising results in a breadth of medical image segmentation tasks, deep neural networks require large training datasets with pixel-wise annotations. Obtaining these curated datasets is a cumbersome process which limits the application in scenarios where annotated images are scarce. Mixed supervision is an appealing alternative for mitigating this obstacle, where only a small fraction of the data contains complete pixel-wise annotations and other images have a weaker form of supervision. In this work, we propose a dual-branch architecture, where the upper branch (teacher) receives strong annotations, while the bottom one (student) is driven by limited supervision and guided by the upper branch. Combined with a standard cross-entropy loss over the labeled pixels, our novel formulation integrates two important terms: (i) a Shannon entropy loss defined over the less-supervised images, which encourages confident student predictions in the bottom branch; and (ii) a Kullback-Leibler (KL) divergence term, which transfers the knowledge of the strongly supervised branch to the less-supervised branch and guides the entropy (student-confidence) term to avoid trivial solutions. We show that the synergy between the entropy and KL divergence yields substantial improvements in performance. We also discuss an interesting link between Shannon-entropy minimization and standard pseudo-mask generation, and argue that the former should be preferred over the latter for leveraging information from unlabeled pixels. Quantitative and qualitative results on two publicly available datasets demonstrate that our method significantly outperforms other strategies for semantic segmentation within a mixed-supervision framework, as well as recent semi-supervised approaches. Moreover, we show that the branch trained with reduced supervision and guided by the top branch largely outperforms the latter. Bibliographic and Citation Tools Code and Data Associated with this Article Recommenders and Search Tools arXivLabs: experimental projects with community collaborators\narXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website.\nBoth individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them.", "pred_label": "__label__POS", "pred_score_pos": 0.6713048219680786} +{"content": "One struggles with the concept of sloth. We enjoy a leisurely weekend on the sofa pretending to “catch-up” on vital recorded sit-coms, all-the-while sleeping soundly as our families cooperate with the fiction. However, on Monday morning, we’re off again to confront the daily battles and, as some might say, silent desperation, of the working, first-world human. Yet, one witnesses our progeny, arguably our closest genetic match, and we judge. Yes, we judge with reckless abandon. How dare they sleep until noon? How dare they eat seemingly endless calories without gaining the telltale weight that befalls those of us who have been blessed by “the good life”?\nBut, now is their time. The sleep is precipitated by unregulated growth and surging hormones. While quarterly calculus finals amuse us compared to mortgage payments and angry in-laws, the stress of youth in present times is real and measurable. Without regard to our own challenges – often addressed as the two-way walk, uphill to school and back – it is true to acknowledge that the modern world has delivered “modern” problems to even the youngest amongst our ranks.\nBut, if present day media has anything to say about it, humanity is doomed. The youth in our midst lack both the ability and the desire to carry their own weight. Could it be true? Are we nearing the end of our reign as the dominant species? Yet, Roy and Katie Appleget from Burlington, Iowa, lived in a tent at a local campground for months on end accumulating the down payment for their first home. While many took handouts, these working-class heroes decided to figure it out on their own. Does the will to succeed exceed our thirst for sloth; or is it simply that Roy and Katie have missed the virtue of Ferragamo or the latest iWhatever?", "pred_label": "__label__POS", "pred_score_pos": 0.9331662654876709} +{"content": "Cord prolapse is often associated with abnormal fetal heart rate tracings due to the compression of the umbilical cord. They can present with fetal heart rate changes, such as variable decelerations with contractions that return to baseline, prolonged or severe decelerations. High suspicion of cord prolapse, with non-reassuring fetal heart rate tracings should prompt delivery via cesarean section regardless of findings on vaginal exam.\nA palpable cord may be found on a vaginal exam if a patient is presenting with spontaneous rupture of membranes, or may occur during an artificial rupture of membranes. It will feel like a pulsatile mass either between the fetal presenting part or alongside the presenting part.", "pred_label": "__label__POS", "pred_score_pos": 0.9999046325683594} +{"content": "The president of the African Development Bank, Akinwumi Adesina has expressed the bank’s worry over Nigeria’s debt to revenue ratio. Adesina, speaking at the opening of the two-day Mid-term Ministerial Performance Review Retreat at the Presidential Villa on Monday in Abuja said despite Nigeria’s debt to the GDP remaining moderate at 35 per cent, the government must take decisive action to tackle its debt challenges for the economy to grow. He said, “Nigeria must decisively tackle its debt challenges. The issue is not about the debt-to-GDP ratio, as Nigeria’s debt-to-GDP ratio at 35% is still moderate. The big issue is how to service the debt and what that means for resources for domestic investments needed to spur faster economic growth. “The debt service to revenue ratio of Nigeria is high at 73%. Things will improve as oil prices recover, but the situation has revealed the vulnerability of Nigeria’s economy. To have an economic resurgence, we need to fix the structure of the economy and address some fundamentals.” According to the Debt Management Office, Nigeria’s total public debt, which includes the federal and state governments, had climbed to N35.46 trillion at the end of the second quarter of 2021. Akinwumi noted that while Nigeria faces the challenge of revenue concentration due to a mainly one-sided source, he stated that structural bottlenecks that limit the country’s productivity need to be removed for other sectors to generate revenue. “Nigeria’s challenge is revenue concentration, as the oil sector accounts for 75.4 % of export revenue and 50 % of all government revenue. “What is needed for sustained growth and economic resurgence is to remove the structural bottlenecks that limit the productivity and the revenue earning potential of the huge non-oil sectors.”", "pred_label": "__label__POS", "pred_score_pos": 0.6888291835784912} +{"content": "As obligate carnivores, cat diets seem pretty straightforward. Yet our favorite felines often get interested in the foods on our plates. And we don't want to deny them the occasional taste test. But how to sort out what's safe from what's harmful? Especially if the same foods are fine for dogs? For instance, can cats eat watermelon? Yes - but only if you're careful. We'll explain.", "pred_label": "__label__POS", "pred_score_pos": 0.9820007681846619} +{"content": "Insurance Status Crucial for In Vitro Fertilization Success Women with insurance coverage for in vitro fertilization are more likely to give birth.\nThe high-cost of in vitro fertilization (IVF) may deter some women and their partners from seeking the procedure. However, those who undergo IVF without insurance coverage may be unlikely to seek a second treatment if the first does not lead to pregnancy, according to a new study published by\nThe Journal of the American Medical Association.\nThe study authors discovered that patients who undergo IVF are more likely to give birth if their health insurance plan covers the procedure, compared with those without coverage.\n\"It's a simple and possibly obvious finding, but it highlights the importance of health insurance in the outcome of fertility treatments,\" said lead author Emily S. Jungheim, MD. \"The biggest hurdle may not be the fertility treatment but the cost.\"\nThe American Pregnancy Association estimates that a single IVF treatment ranges from $12,000 to $17,000, with a success rate of more than 40% for those under 35 and 15% for those over 40.\nIt is known that age, lifestyle, cause of infertility, and reproductive history all play a role in the success of IVF, but the new study indicates that insurance status and related costs also are involved.\nIncluded in the study were 1572 women who sought IVF from 2001 to 2010 at Washington University’s Fertility and Reproductive Medicine Center, which provides services for women located in Missouri and Illinois. The authors reported that the location of the clinic is significant because Illinois requires IVF coverage, while Missouri does not.\nApproximately 56% of participants had coverage for the procedure, and 44% of participants paid for IVF out-of-pocket. Patients with insurance were observed to be slightly younger than those without coverage, according to the study.\nOf the women with insurance coverage, 70% received an additional treatment if the first did not result in pregnancy.\nFor women with IVF coverage, the likelihood of birth after 4 attempts was 59% (515 births), and for women without coverage, the likelihood was 51% (350 births), according to the study. These findings were deemed statistically significant.\n\"The 2 groups were medically similar and had the same outcomes in individual cycles after controlling for factors such as age,\" Dr Jungheim said. \"The difference is that women with coverage were more likely to come back and try again if they were initially unsuccessful. Given that they had the ability to try more times, they had a higher chance of giving birth.\"\nFifteen states have insurance laws that mandate coverage of infertility services, but only 5 states’ laws include coverage for IVF. Expanding coverage for IVF may increase the likelihood of birth and could reduce costs in the long term.\nThe authors noted that their findings may be limited due to the inclusion of data from only 1 fertility center, and some patients may have received additional treatments at other clinics, according to the study.\n\"However, these findings highlight the critical role insurance plays in determining whether a woman with fertility issues ultimately will have a baby,\" Dr Jungheim concluded. \"Legislation mandating IVF insurance coverage may improve the delivery and outcomes of fertility treatments.\"", "pred_label": "__label__POS", "pred_score_pos": 0.7003197073936462} +{"content": "The NHTSA wrote Tesla a letter demanding an explanation for why it hasn’t recalled its Autopilot driver assistance feature.\nThe headquarters relocation serves as a capstone to several years of Tesla investment in the state.\nEV market share in Europe has surpassed diesel for the first time, marking a pivotal moment in the region’s mainstream adoption of the technology.\nInvoking the Defense Production Act may be an imperfect but necessary step towards fixing the chip shortage: The Biden administration is split on using the Cold War-era law.\nLaw enforcement officials claim a Model X with Autopilot engaged injured five police officers—more fuel forregulators’ growing scrutiny of Tesla.\nSilicon batteries could resolve lithium-ion battery shortage and save carmakers money: Researchers created a solid-state silicon battery they say lasts longer and charges faster than lithium-ion batteries.\nEV recycling could be a win-win for recycling startups and carmakers: Ford’s $50M investment in Redwood Materials creates a partnership to build a US-based battery supply chain.\nThe UK’s digital advertising industry weathered the pandemic remarkably well. Among the industry sectors we track, digital ad spending will rise across the board (which was not universal last year), but these patterns of growth will fluctuate wildly across categories.\nTesla may need to expand eye-tracking tech for inattentive Autopilot drivers: A new study may confirm that Autopilot users aren’t paying enough attention to the road—which compounds scrutiny the automaker is already facing amid plans to expand its driverless features.\nGM will extend its Bolt EV production delay due to a battery pack shortage. Increased demand for EVs may only aggravate the problem.", "pred_label": "__label__POS", "pred_score_pos": 0.5850603580474854} +{"content": "A\nWisconsin month-to-month lease agreement is a periodic rental arrangement entered into by a landlord and tenant that has no predetermined expiration. The contract allows the tenant to renew their lease with each monthly payment until they or the landlord gives the other party notice to terminate. A monthly rental agreement is preferable for tenants whose situation doesn’t allow them to make the year-long commitment of a standard lease.\nIt is recommended that landlords charge a security deposit and have potential tenants complete a rental application for security against monthly tenants defaulting on rent or quitting the property without notice. Either party can terminate the tenancy with at least twenty-eight (28) days’ notice unless another notice period is established in the rental contract.\nNotice for terminating (§ 704.19(3)) – Twenty-Eight (28) Days Tenant screening – Wisconsin Rental Application\nIf a property violates any building or housing code and threatens the health and safety of its occupants, the landlord is required to disclose this information to prospective tenants before signing a lease agreement.\nLandlords cannot accept security deposits without first disclosing the prospective tenant’s right to perform an inspection of the dwelling unit and receive a document itemizing the damages that incurred deductions to the previous tenant’s security deposit.\nThe names and addresses of the property owner and individuals authorized to receive rent and maintain the property, and the owner’s representatives to whom service of process and notices can be sent must be disclosed to the tenant before the start of their residence.\nLandlords are obligated to complete this disclosure if they lease a rental unit built before 1978.\nBefore the tenant enters into a rental agreement or pays a security deposit, the landlord must first indicate if the utility charges are included in the rent. If the tenant is renting a unit in a property that does not have individual metering for its utility services, they must be informed of how the utility charges will be allocated.", "pred_label": "__label__POS", "pred_score_pos": 0.9598814249038696} +{"content": "A car accident is a difficult experience on its own, but becomes even worse when the at-fault driver does not have insurance. Their lack of insurance could very well leave you holding the bill for damages they caused.\nYou may already have coverage\nThere is a form of insurance coverage you may have that can help pay for your injuries and other losses if the other driver was uninsured or underinsured. This is known as uninsured/underinsured (UI/UIM) coverage. Insurance companies in Wyoming are required to offer it, but drivers can opt out by providing a written letter to their insurer. If you have unenrolled from this coverage, you may still be able to file a claim directly against the at-fault driver. However, drivers who are uninsured or underinsured may not be able to afford to cover your costs in the event of an accident.\nYou do not have to go through this alone\nIf you are trying to secure the compensation you need after a car crash, contact an experienced personal injury attorney. They can help you either seek compensation from your insurance or that of the driver who hit you.", "pred_label": "__label__POS", "pred_score_pos": 0.8287645578384399} +{"content": "The Best Practices do not make assumptions about:\nthe size of the organisation applying them;\nthe machine learning technologies used; and/or\nthe domains or fields they are being applied to.\nThis means that the Best Practices are written in a general manner, and their contextual relevance (whether collectively or for each part) will differ from case to case. Again, this highlights the importance of context and its appreciation. This means that risks that are very particular to, for example a specific technology or domain, are not included in the Best Practices.\nThis also means that applying the Best Practices is no guarantee that machine learning applications will be inherently ethical, safe or responsible. There are simply too many context relevant details for each product that cannot be captured in a general framework to achieve this. However, the Best Practices will help to move significantly towards ensuring ethical, safe and responsible machine learning if applied with appreciation for the context determined risks.", "pred_label": "__label__POS", "pred_score_pos": 0.5291785001754761} +{"content": "ABSTRACT\nThe future of wind and photovoltaic (PV) power and its projected growth, expressed as a percentage of the total electricity demand in the world, are discussed in this chapter. The historical data on market developments in similar basic-need industries and the Fisher-Pry market growth model indicate that PV and wind power may reach their full potential in the year 2065. The probable impact of the U.S. utility restructuring on renewable energy sources is reviewed.", "pred_label": "__label__POS", "pred_score_pos": 0.8984014391899109} +{"content": "After logging in to Illume Impact, you will see a home page showing all Completed initiatives by default. This will include initiatives submitted by all Illume Impact users at your institution. An initiative appears in the Completed tab after it's been submitted to Illume Impact and the persistence lift has been calculated after PPSM.\nEach Completed initiative has a corresponding card, showing basic details about the initiative and the results of impact analysis.\nThe top of the card indicates the\nlift in persistence that was measured for this initiative using Illume Impact. Persistence is defined as a student re-enrolling for the next term and staying enrolled past your institution's census date (or add/drop period) or graduating. It's important to understand how this lift is calculated and which students are included in analysis. Refer to to see a detailed explanation of the values used in this calculation. How is persistence lift calculated?\nAn icon on the initiative card indicates the result of the initiative on persistence outcomes.\nA green icon with an upward arrowshows a statistically significant (p-value less than 0.05) increase in the persistence rate of participants. A red icon with a downward arrowshows a statistically significant (p-value less than 0.05) decrease in the persistence rate of participants. A gray icon with a dashshows that the effect on persistence for participants was not statistically significant. An initiative may not have statistically significant impact results if the number of matched participants and comparison students was low (e.g. fewer than 1,000 students), if there was a lot of variability in the results of bootstrapped samples, or if the persistence lift was very small. On the other hand, an initiative with a small number of students included in analysis may still show statistically significant results if the persistence lift was very pronounced. Results that are not statistically significant could still be meaningful. At this point, you may consider collecting more data before redoing the analysis or rethinking the initiative design.\nBeneath the lift in persistence, find other information about the initiative:\nConfidence interval:The percentage indicated beneath the lift in persistence (e.g. +/- 1.6%) shows the 95% confidence interval for this initiative's impact results. The is calculated by multiplying the standard deviation of measured impact across multiple bootstrapped samples by 1.96. Initiative Name: The name given to this initiative by the user who added it. Number of Analyzed Participants: The number of participant students submitted in the uploaded student list who were matched with a comparison student through PPSM. This number represents the total number of participant-comparison student pairs used for impact analysis. Initiative Goal: The goal for this initiative that was entered by the user who added it. Analyzed Terms:The start and end terms included in the uploaded file, if these terms are verified and kept during data validation. If you choose to ignore either of these terms during data validation, you will see the earliest and latest terms that were actually submitted. Submission Details:The date this initiative was added and the name of the user who added it.\nClick the search icon in the upper righthand corner to find a specific initiative. Type the name of the initiative into the search box to see matches.\nNarrow down the initiatives you see on the home page by clicking 'Filter' to the left of the search icon.\nAvailable filters include:\nLift in Persistence: View only the initiatives where a positive lift in persistence was observed or only those where a negative lift was observed, or hide initiatives that did not have statistically significant results. Submission Time Period: View only the initiatives submitted this week, this month, or this year. Start and End Terms: Select a start and end term to view only the initiatives that took place during the specified range. Number of Analyzed Participants: Move the slider to view only the initiatives where the number of analyzed participants was within the specified range.\nSelect as many filters from each category as you would like. After selecting filters, click the Apply Filters button to refresh the home page. To modify your filter selections, click the 'x' to the right of any selection or click 'Clear All Filters' to the right of your selections.\nIf you're looking for a recently added initiative, impact analysis may not be complete. Check the Pending tab to see initiatives still in progress.\nIf initiative analysis failed, the initiative card will remain in the Pending tab and you'll see a red 'x' icon in the upper righthand corner of the card.\nTo resubmit the initiative with the same data file and previously submitted information, click the card flip icon in the lower righthand corner. Select the option to \"Resubmit Initiative\" and initiative analysis will begin again using the same data set and details.", "pred_label": "__label__POS", "pred_score_pos": 0.9545886516571045} +{"content": "Immune therapy added to chemotherapy improves pathological complete response in patients with early triple negative breast cancer, according to results from the\nKEYNOTE-522 trial presented at the ESMO Congress 2019 in Barcelona, Spain. Interim results from the study, which is the first phase III trial of immunotherapy in early breast cancer, also indicated an improvement in event-free survival. \"The data suggest that the improved pathological complete response with pembrolizumab translates into fewer recurrences,\" said study author Professor Peter Schmid, Barts Cancer Institute, Queen Mary University of London, UK.\nTriple negative breast cancer is the most aggressive subtype of breast cancer and more often affects young women. Patients typically receive chemotherapy, followed by surgery to remove the tumour. This provides the best chance of pathological complete response, meaning no cancerous cells remaining on the resected tumour. Women with a pathological complete response have an 85-90% likelihood of being cured, while those with residual viable tumour tissue have a 40-50% probability of recurrence, which often occurs within three years.\nKEYNOTE-522 tested whether adding immune therapy to chemotherapy prior to surgery could improve pathological complete response and event-free survival in women with early triple negative breast cancer. A total of 1,174 patients were randomly allocated at a 2:1 ratio to pembrolizumab or placebo, both added to preoperative chemotherapy with anthracyclines, taxanes, and platinum, for five to six months. After surgery, patients continued their allocated treatment of pembrolizumab or placebo for nine cycles.\nThe analysis presented at the ESMO Congress 2019 was performed after a median follow-up of 15.5 months. Pathological complete response, assessed in the first 602 patients, significantly increased from 51.2% (95% confidence interval [CI] 44.1-58.3) in the placebo group to 64.8% (95% CI 59.9-69.5) in the pembrolizumab group (p=0.00055). \"We found a 13.6% difference which is a clinically meaningful benefit,\" said Schmid.\nBecause triple negative breast cancer is aggressive and recurrences often occur early on, the investigators conducted an interim analysis of event-free survival. There was a favourable trend for the pembrolizumab group with a hazard ratio of 0.63 (95% CI 0.43-0.93), Schmid said: \"These are preliminary data, but they provide a strong sign that the addition of immune therapy to neoadjuvant chemotherapy prevents breast cancer recurrence. If we prevent recurrence, we cure more patients, but we need longer-term data for confirmation.\"\nGrade 3 or higher treatment-related adverse events occurred in 78.0% and 73.0% of the pembrolizumab and placebo groups, respectively. Schmid noted that many of the side-effects were driven by the intensive chemotherapy regimen. Side-effects with a potential link to immune therapy occurred in 42% of study participants taking pembrolizumab versus 21% on placebo. \"Immune therapy added some side-effects to chemotherapy but there were no new safety signals,\" he said.\nCommenting on the results for ESMO, Professor Fabrice Andre,\nInstitut Gustave Roussy, Villejuif, France, said: \"Triple negative breast cancer accounts for 15% of breast cancers. It represents an unmet medical need, since the only approved medical therapy at early stages of the disease is chemotherapy. This study could have a major impact on treatment for these patients.\"\nAndre noted that pathological complete response is a valid endpoint for\nUS Food and Drug Administration (FDA) approval. \"This is a good situation to test whether the FDA will approve a drug for triple negative breast cancer based on pathological complete response. The combination of the anti-PD-1 monoclonal antibody pembrolizumab plus chemotherapy could become a standard of care if approved,\" he said.\nWhile a large benefit in response rates was expected, the poor predictive value of PD-L1 was surprising. \"This is probably because most early stage triple negative breast cancers express some degree of PD-L1, sometimes below the predefined cut-off of positivity. The role of chemotherapy as a sensitiser for anti-PD-1 in PD-L1-low early stage triple negative breast cancer should also be explored,\" said Andre. \"The next step will be to define which patients are resistant and prioritise which targets should be hit in this population. We also have to determine the impact of this new class of drug on survivorship issues.\"\nAbstract Background: Neoadjuvant pembro + chemo had manageable safety and promising antitumor activity in participants (pts) with early TNBC in KEYNOTE-173 and I-SPY 2. KEYNOTE-522 (NCT03036488) is a pbo controlled phase 3 study of neoadjuvant pembro + chemo followed by adjuvant pembro in pts with early TNBC. Methods: Pts with previously untreated, non-metastatic, centrally confirmed TNBC (stage T1c N1-2 or T2-4 N0-2 per AJCC) were randomized 2:1 to pembro 200 mg Q3W or pbo, both given with 4 cycles of paclitaxel + carboplatin, then with 4 cycles of doxorubicin or epirubicin + cyclophosphamide (neoadjuvant phase). After definitive surgery, pts received pembro or pbo for 9 cycles or until recurrence or unacceptable toxicity (adjuvant phase). Pts were stratified by nodal status (+ vs -), tumor size (T1/T2 vs T3/T4), and carboplatin schedule (Q3W vs QW). Dual primary endpoints were pCR defined as ypT0/Tis ypN0 and event-free survival (EFS). Secondary endpoints included pCR defined as ypT0 ypN0 and ypT0/Tis, OS, and efficacy in the PD-L1+ population. Results: Median follow-up was 15.5 mo (range, 2.7-25.0). 784 pts were randomized to pembro, 390 to pbo. Among 602 pts evaluable for the definitive pCR analysis, pembro + chemo showed a statistically significant improvement in pCR (ypT0/Tis ypN0) vs pbo + chemo: 64.8% (95% CI, 59.9-69.5) vs 51.2% (95% CI, 44.1-58.3), P = 0.00055; results were consistent for the secondary pCR definitions, ypT0 ypN0 (59.9% vs 45.3%) and ypT0/Tis (68.6% vs 53.7%). For pembro vs pbo, pCR (ypT0/Tis ypN0) was 68.9% vs 54.9% in the PD-L1+ population and 45.3% vs 30.3% in the PD-L1- population. The addition of pembro to chemo followed by pembro showed a favorable trend in EFS (HR 0.63 [95% CI, 0.43-0.93]). Across phases, grade 3 or higher treatment-related AE rates were 78.0% in the pembro + chemo group and 73.0% in the pbo + chemo group (death incidence, 0.4% vs 0.3%, respectively). Conclusions: Addition of pembro to neoadjuvant chemo significantly increased the pCR rate in pts with early TNBC. Neoadjuvant pembro + chemo followed by adjuvant pembro showed a favorable trend in EFS. AEs were consistent with the known safety profiles of each agent. Authors P Schmid, J Cortés, R Dent, L Pusztai, HL McArthur, S Kuemmel, J Bergh, C Denkert, YH Park, R Hui, N Harbeck, M Takahashi, T Foukakis, P Fasching, F Cardoso, L Jia, V Karantza, J Zhao, G Aktan, J O'Shaughnessy\n[link url=\"https://medicalxpress.com/news/2019-09-immune-therapy-tumour-cells-early.html\"]Medical Xpress report[/link]\n[link url=\"https://www.esmo.org/Press-Office/Press-Releases/ESMO-Congress-TNBC-breast-cancer-immunotherapy-Keynote522-Schmid\"]ESMO 2019 abstract[/link]", "pred_label": "__label__POS", "pred_score_pos": 0.6124935150146484} +{"content": "Modern organizations use a combination of hard physical security controls to protect their people, assets and intellectual property. In application, defence-in-depth employs successive layers of hard physical security controls across zones to manage risks. Yet those incredibly effective controls can be costly and time-consuming to reconfigure.\nRightCrowd Presence Control introduces a simple new approach to adding physical defense-in-depth. The technology validates physical security permissions by making them visible. The solution leverages an existing building access card and adds a RightCrowd Digital Badgeholder, enabling both human and automated validation of security permissions for everyone present.\nSliding your existing building access card into the Badgeholder enables an internal NFC reader, that reads the credential from the card and activates the Bluetooth wearable. The card and Badgeholder merge physically and link logically through backend software. This combined credential now leverages NFC and BLE to manage physical access and presence.\nRightCrowd Presence Control provides the following benefits: Cost effective– quickly implement additional security controls without creating a large capital project. Flexible solution– the solution can be deployed within days and can be easily moved to another location. Two-factor authentication for physical security– anyone not authorized to be in an area will be immediately visible to everyone else. Integrates with existing access control– turns an existing building access card into a digital security wearable. Activate your next layer of security\nEnsure that everyone present in the workplace is meant to be there. To find out more, contact a RightCrowd security expert today.", "pred_label": "__label__POS", "pred_score_pos": 0.5857807993888855} +{"content": "Files Abstract\nDespite its generic title, this thesis is about a specific notion of sparsity, the one introduced by McCullagh and Polson (2018). In that paper, the intuitive idea that sparsity, in a statistical framework, refers to those ''phenomena that are mostly negligible or seldom appreciably large'', has, for the first time, been given a mathematical definition. In studying this definition of statistical sparsity as a limiting property of a sequence of probability distributions, research has proceeded along different lines, which nevertheless intersect at all times. In all cases, our work has been driven by both theoretical and practical motivations. The notion of negligibility, for instance, is developed from the necessity of describing the behavior of a sparse distribution in a region around zero, a necessity which is commonly encountered in applied work. At the same time, doing this in a mathematical way, allows us to define very clearly what is the perimeter within which this notion is informative, and can be used. Another main direction of research we pursue, aims at extending the definition of sparsity to distributions which are defined on d-dimensional vector spaces, d>1. Within this framework, we consider two scenarios: in the first one, the d-dimensional measure is a product of d one-dimensional sparse measures; in the second one, instead, the d-dimensional measure is rotationally invariant with respect to the inner product imposed on R^d, and sparsity is driven by the radial component. For both cases, we develop some theory as well as present how this theory can be in fact applied in the context of various statistical problems.", "pred_label": "__label__POS", "pred_score_pos": 0.7685472965240479} +{"content": "Preventative Roof Maintenance and Tune-Ups\nMaintaining a sound roof literally tops the list of crucial home repairs: It keeps you and your family warm, dry, and protected, along with everything in your house.\nThis page is under construction. Please check back soon!\n(This page will discuss preventative leak and rodent maintenance for repairs on wood, composition, commercial and residential flat roofs; mainly speaking of checking specific flashings and age wear and tear, gutter and downspout maintenance, as well as concerns that develop after approximately 8-10 years regarding shingles, shakes, and ridges. Moss clean up and roof debris will also be a factor, along with roof coatings for aged flat roofs.)", "pred_label": "__label__POS", "pred_score_pos": 0.5451565384864807} +{"content": "4th District Congressman Jim Himes has introduced the ‘Safe to Tell Act of 2018’. The legislation, if enacted, will provide federal grants to states that choose to establish and maintain an anonymous, 24/7 monitored venue to alert law enforcement about potential threats of violence at schools.\nThe legislation would require those states seeking a grant to present a framework in which parents, students, teachers, and school administrators can effectively and efficiently share information regarding potential threats with law enforcement and school safety officials. The measure is based on Colorado's ‘Safe2Tell’ program, pioneered after the shootings at Columbine High School in 1999.\nThe proposal calls for $25 million for each fiscal year from through 2023. It also provides states with the autonomy to decide how to best implement the program in their jurisdictions, while setting standards and requirements. Some of these include establishing guidelines and transmitting methods of anonymous reports, proper channel routing for prompt and effective local law enforcement responses and built-in accountability standards, among others.", "pred_label": "__label__POS", "pred_score_pos": 0.7193433046340942} +{"content": "Takeaway\nPain extent determined from pain drawings in women with carpal tunnel syndrome (CTS) is not associated with clinical, psychological or psychophysical variables nor is it related to the severity or laterality of symptoms.\nWhy this matters\nPain conditions vary considerably and methods investigating pain levels and severity may aid in clinician decision on pain sensitivity or more severe clinical features.", "pred_label": "__label__POS", "pred_score_pos": 0.9675267934799194} +{"content": "450,000 Texans Have A Gambling Problem\nAbout 1 percent of the adult population in the U.S. has a severe gambling addiction, according to the National Center for Responsible Gaming. A 2016 Census Bureau estimate found that 2.2 percent of Texas adults are believed to have manifested a gambling problem.\nThe American Psychiatric Association refers to the addiction as \"gambling disorder,\" characterized by \"persistent and recurrent problematic gambling behavior\" that can lead to significant impairment or distress.\nAlso referred to as \"compulsive gambling,\" the condition can lead to disruption in all aspects of person's life, including family, finances and work. In 2016, approximately $5.1 billion was spent on legalized gambling in Texas.\nWhat counts as gambling and when does it become concerning behavior? Does technology play a role in this kind of addiction?\nWhat should you do if you suspect you or someone you love might have a gambling problem?\nGuests: Keith Whyte, executive director of the National Council on Problem Gambling Arnie Wexler, co-author of \"All Bets Are Off: Losers, Liars, and Recovery from Gambling Addiction\" Lia Nower, professor and director of the Center for Gambling Studies at Rutgers University", "pred_label": "__label__POS", "pred_score_pos": 0.9244382381439209} +{"content": "Our Favorite GIS Data Collection Tools in 2021\nGIS data collection requires the right hardware. This guide covers GPS units, digitizers, mobile devices, and other useful GIS tools.\nCybersecurity breaches in critical infrastructure networks are increasing. With prompt action and better understanding of new cybersecurity threats - critical infrastructure providers can own the solution.\nThe most expensive part of any GIS project is often field data collection: a process that is frustrating, inefficient, and complex. By enabling data capture, transfer, and storage from a single device, cloud-based geospatial software is the ideal solution.\nExtreme weather poses an existential threat to utilities - innovation in emergency response is key to saving lives and avoiding harsh penalties.\n'Cyber-hygiene' - firewalls, anti-virus software, etc. - is often conflated with cybersecurity. But this neglects an urgent vulnerability: the software supply chain.", "pred_label": "__label__POS", "pred_score_pos": 0.6013771295547485} +{"content": "(2020)\nThe early detection of gastric cancer (GC) could decrease its incidence and mortality. However, there are currently no accurate noninvasive markers for GC screening. Therefore, we developed a noninvasive diagnostic approach, employing urine nuclear magnetic resonance (NMR) metabolomics, to discover putative metabolic markers associated with GC. Changes in urine metabolite levels during oncogenesis were evaluated using samples from 103 patients with GC and 100 age- and sex-matched healthy controls. Approximately 70% of the patients with GC (n = 69) had stage I GC, with the majority (n = 56) having intramucosal cancer. A multivariate statistical analysis of the urine NMR data well discriminated between the patient and control groups and revealed nine metabolites, including alanine, citrate, creatine, creatinine, glycerol, hippurate, phenylalanine, taurine, and 3-hydroxybutyrate, that contributed to the difference. A diagnostic performance test with a separate validation set exhibited a sensitivity and specificity of more than 90%, even with the intramucosal cancer samples only. In conclusion, the NMR-based urine metabolomics approach may have potential as a convenient screening method for the early detection of GC and may facilitate consequent endoscopic examination through risk stratification.", "pred_label": "__label__POS", "pred_score_pos": 0.7971598505973816} +{"content": "Hydrogen embrittlement (HE) is a phenomenon that affects both the physical and chemical properties of several intrinsically ductile metals. Consequently, understanding the mechanisms behind HE has been of particular interest in both experimental and modeling research. Discrepancies between experimental observations and modeling results have led to various proposals for HE mechanisms. Therefore, to gain insights into HE mechanisms in iron, this dissertation aims to investigate several key issues involving HE such as: a) the incipient crack tip events; b) the cohesive strength of grain boundaries (GBs); c) the dislocation-GB interactions and d) the dislocation mobility.\nThe crack tip, which presents a preferential trap site for hydrogen segregation, was examined using atomistic methods and the continuum based Rice-Thompson criterion as sufficient concentration of hydrogen can alter the crack tip deformation mechanism. Results suggest that there is a plausible co-existence of the adsorption induced dislocation emission and hydrogen enhanced decohesion mechanisms. In the case of GB-hydrogen interaction, we observed that the segregation of hydrogen along the interface leads to a reduction in cohesive strength resulting in intergranular failure. A methodology was further developed to quantify the role of the GB structure on this behavior.\nGBs play a fundamental role in determining the strengthening mechanisms acting as an impediment to the dislocation motion; however, the presence of an unsurmountable barrier for a dislocation can generate slip localization that could further lead to intergranular crack initiation. It was found that the presence of hydrogen increases the strain energy stored within the GB which could lead to a transition in failure mode. Finally, in the case of body centered cubic metals, understanding the complex screw dislocation motion is critical to the development of an accurate continuum description of the plastic behavior. Further, the presence of hydrogen has been shown to drastically alter the plastic deformation, but the precise role of hydrogen is still unclear. Thus, the role of hydrogen on the dislocation mobility was examined using density functional theory and atomistic simulations. Overall, this dissertation provides a novel atomic-scale understanding of the HE mechanism and development of multiscale tools for future endeavors.", "pred_label": "__label__POS", "pred_score_pos": 0.9427466988563538} +{"content": "Yiqing worked with the lab as a Data Science Specialist – Epidemiologist during 2020-2021, before starting her PhD training at McGill University in September 2021.\nShe holds a Bachelor’s degree in Medicine and a Master of Science degree in Public Health. Prior to joining MAP Centre for Urban Health Solutions in August 2020, she worked as a research assistant in the Department of Epidemiology, Biostatistics, and Occupational Health at McGill University for 1.5 years. She has 6 years of research experience in the area of infectious diseases, and 1.5 years of experience in HIV transmission modeling.\nShe led multiple projects related to COVID-19, including studying factors driving the observed differences in the trajectory of the sub-epidemics within and between provinces, hospital capacity projections, and estimating the effective reproduction number.\nYiqing publications with the team include:\nXia Y.Godin A. *, * [*co-first author], Buckeridge DL., Mishra S., … Brisson M., Maheu-Giroux M. The role of case importation in explaining differences in early SARS-CoV-2 transmission dynamics in Canada – a mathematical modeling study of surveillance data. (* Godin A and Xia Y. contributed equally to the work). IJID.Volume 102. Pages 254-259. doi: 10.1016/j.ijid.2020.10.046. Xia Y, Ma H, Moloney G, García HAV, Sirski M, Janjua N, Vickers D, Williamson T, Katz A, Yu K, Kustra R, Buckeridge D, Brisson M, Baral S, Mishra S, Maheu-Giroux M. (2021). Geographical concentration of COVID-19 cases by social determinants of health in 16 large metropolitan areas in Canada – a cross-sectional study. [Preprint available]. Mishra S, Ma H, Moloney G, Yiu K.C.Y, Darvin D, Landsman D, Kwong J.C., Calzavara A, Straus S, Chan A.K., Gournis E, Rilkoff H, Xia Y, Katz A, Williamson T, Malikov K, Kustra R, Maheu-Giroux M, Sander S, Baral S. (2021). Increasing concentration of COVID-19 by socioeconomic determinants and geography in Toronto, Canada: an observational study. Ann Epidemiol.doi: 10.1016/j.annepidem.2021.07.007.", "pred_label": "__label__POS", "pred_score_pos": 0.7492178678512573} +{"content": "«LIKE IN A SHELL» INTERAFFECTIVITY AND SOCIAL COGNITION IN ASPERGER’S SYNDROME DOI:https://doi.org/10.13136/thau.v6i0.97 Keywords:Autism Spectrum Disorder, Asperger’s Syndrome, Georg Frankl, Interaffectivity, Intercorporeality, Treatments, Affective Contact, Affective Language Abstract\nIn this paper, I argue that the real limitation of Asperger’s subjects lies in ntercorporeality and interaffectivity, that is, in the pre-reflective, intersubjective engagement with others. I begin by first drawing on the work of the psychiatrist Georg Frankl, and I describe this engagement in terms of “affective language” and “affective contact”. In the second part of the paper I emphasize how Frankl’s account can be coherent with a phenomenological perspective on sociality. In closing I propose a therapeutic technique aimed at strengthening the intercorporeal, affective abilities of the subjects.\nDownloads Published Issue Section License\nThe contents of this work are protected under a Creative Commons 4.0 Attribution-NonCommercial-4.0\nInternational License (https://creativecommons.org/ licenses/by-nc/4.0).", "pred_label": "__label__POS", "pred_score_pos": 0.7572442293167114} +{"content": "Dr. Gregory Hudalla, Dr. Edward Phelps, and lab members’ recent work, “Physical tuning of galectin-3 signaling,” has been published by the\nNational Academy of Sciences Proceedings of Sciences the United States of America (PNAS).\nTeam members:\nShaheen A. Farhadi, Ph.D., postdoctoral researcher, Hudalla Lab Renjie Liu, Ph.D., postdoctoral researcher, Hudalla Lab Mithra Becker, Ph.D. student, Phelps Lab Edward Phelps, Ph.D., Assistant Professor & J. Crayton Pruitt Family Term Fellow, Department of Biomedical Engineering, University of Florida Gregory Hudalla, Ph.D., Associate Professor, Department of Biomedical Engineering, University of Florida Significance\nThe family of carbohydrate-binding proteins known as galectins receive considerable attention for their ability to modulate cell behavior in both normal and pathological settings. Galectin-3, for instance, can crosslink membrane glycans to initiate, amplify, attenuate, or inhibit signal transduction pathways that lead to cell differentiation, proliferation, or death. However, understanding structure–function relationships of galectin-3 is challenged by its promiscuous glycan-binding properties and assembly into oligomers with undefined number of subunits or “valency.” Here, we address these challenges by providing a toolbox of synthetic galectin-3 oligomers with tunable valency. Cell-based studies with these oligomers suggest a role for physical size as a structural determinant of galectin-3 signaling function, in addition to the increased binding strength typically associated with multivalency.", "pred_label": "__label__POS", "pred_score_pos": 0.6566584706306458} +{"content": "The Philippines recently signed a deal with the United States government for a technical assistance grant worth roughly $700,000 aimed at implementing an intelligent transportation system. This assistance is set to take place until December 2022. An intelligent transport system consists of a series of digital applications which are intended to improve transport services. These systems are essential for a city’s evolution into a ‘smart city’, in other words one supported by holistically-integrated digital mechanisms with the goal of optimising daily life. Efficient mobility is at the crux of a city remaining liveable and competitive. Intelligent transportation systems harness automatised data collection and precise location information to save city inhabitants’ time and improve their journey experience. System users gain insight into data points including traffic flow, real-time running information and seat availability. Thus transport networks are used in a smarter way. Glasgow is an example of a city which has implemented this type of system with success: daily commuters on public buses are furnished with regular information regarding timings, seat availability, location of buses and density of bus passengers.\nThese systems not only improve user experience but also are environmentally friendly, since vehicle energy consumption can be reduced. This is particularly beneficial to Metro Cebu, where rapid growth has led to an accelerating urban sprawl. According to an OECD study, the absence of an integrated, high-capacity transport system has led to increasingly high levels of private vehicle ownership. This creates both further congestion and urban pollution. Hence efficient, clean transport options will be extremely valuable.\nThis grant will be principally aimed at the Cebu transportation department’s Cebu Bus Rapid Transport project, which is already enjoying financial support from the Agence Française de Développement (AFD) and the World Bank (WB). This project is one of many that are part of\nPresident Rodrigo Duterte's ‘Build, Build, Build’ program. It is clear that Metro Cebu’s digital transformation is advancing at a strong pace.", "pred_label": "__label__POS", "pred_score_pos": 0.9723279476165771} +{"content": "Chapter Title/Book Title\nRole Transitions\nBook Title\nEssays in Developmental Psychology\nEditors\nRandall Summers, Charles Golden, Lisa Lashley, & Erica Ailes\nFiles\nDownload Full Text\nDocument Type\nEssay\nAbstract/Excerpt/Description\nExcerpt\nA role can be defined as one’s position in a relationship or social structure, whereas a role identity consists of the behavioral expectations that are included in that role. While some individuals may view their roles through a fixed set of social standards, others rely on their own subjective perceptions and interpretations of these positions through flexible guidelines. Through the process of a role transition, the literature identifies two types defined as a macro role transition or micro role transition. A macro role transition consists of a psychological or physical change between consecutively held roles. Examples can include career transitions, marriage/divorce, parenthood, immigration, or retirement. A micro role transition is also considered a psychological or physical change, yet between simultaneously held roles. For instance, shifts may occur between one’s home and work roles, roles between parent and spouse, or movement between or within social domains (e.g. school, religious groups, social organizations).\nKeywords\nbehavioral expectations, home and work roles, identity, macro role transition or micro role transition, relationship, role transitions, social domains, social structure\nPublication Date\n2020\nDisciplines\nPsychology\nNSUWorks Citation\nFornalski, N. M.,Lashley, L. K.,Golden, C. J.(2020). Role Transitions.\nEssays in Developmental Psychology. Available at: https://nsuworks.nova.edu/cps_facbooks/711", "pred_label": "__label__POS", "pred_score_pos": 0.7121592164039612} +{"content": "Difficulty is inevitable, but regret is a choice. No matter what path we choose, we will face difficulty along the way. This cannot be avoided. Of course, some paths will be easier than others, but none will be free of difficulty. If difficulty is inevitable, the choice we must make, then, is not which path…\nJust because something seems impractical, does not mean that we should avoid attempting it. In fact, nearly all great change in the world is made by people who had the bravery, the arrogance, or the stupidity to attempt something impractical. Practicality is measured in what has worked, what usually works, and what is expected to…\nWhen we experience fear, it is quite often a sign that what we are doing is important. If what we are doing is of no real consequence, if there is no risk involved, or if it simply does not matter to us or to others, there is no reason to be afraid. But, when what…\nOur fears grow stronger when ignored or denied. They do not resolve themselves. They require our attention and our effort. They must be faced head on. If we are to overcome our fears, we must take action. We must move toward them. We must challenge them. We must challenge ourselves. Even this does not guarantee…\nFear makes us think, say, and do all sorts of strange things. It warps our perspective so that everything looks, sounds, and feels different. Fear makes life seem more hostile and threatening than it may actually be. Where we were once confident, fear gives us doubts. Where we were once strong, fear makes us feel…", "pred_label": "__label__POS", "pred_score_pos": 0.6348605155944824} +{"content": "ENERGY SURVEYS\nTecnoVeritas provides energy surveys for ships, SEEMP and EEDI services. Fuel accounts typically between 35 and 65% of ship’s total operating costs. Nowadays, energy optimization is playing a vital role in the market dominated by increasing fuel prices and environmental awareness.\nThe identification of energy saving opportunities results in a decrease in fuel costs and emissions. It also reduces the vessel systems downtime, which increases the vessel availability.\nBut how to determine these saving opportunities? That’s where TecnoVeritas step in, offering a range of ship energy services, customizable accordingly to your needs:\nENERGY AUDIT\nIt determines how energy is being lost, what systems are operating inefficiently and what can be implemented to reduce consumption.\nSEEMP Ship Energy and Emissions Monitoring Plan (SEEMP) is a way to reduce emission and fuel consumption on vessels. EEDI Energy Efficiency Design Index (EEDI) is an index, for news vessels, that relates CO 2 emissions and cargo.", "pred_label": "__label__POS", "pred_score_pos": 0.9058438539505005} +{"content": "The Last Line of Defense Against Forest Destruction\nDuring the COVID-19 pandemic, governments’ failures to address the needs of Indigenous communities revealed significant disparities in their access to healthcare and other services. Increasingly, Indigenous peoples are exposed to the worst effects of climate change, and to violations of their rights to land and resources.", "pred_label": "__label__POS", "pred_score_pos": 0.9437097907066345} +{"content": "V. Jyothi and M. Suresh Kumar\nThe study was conducted during 2011-2012 in the adopted village of Agricultural College, Naira, Srikakulam District of Acharya N.G. Ranga Agricultural University, Andhra Pradesh. Sociometry was applied to probe the key communicators in dissemination of agricultural information. Sixty (60) farmers were sampled for the study. The respondents were asked from whom they seek advice or suggestion in matters related to agriculture in general. Their responses were noted and key communicators were identified and diagrammatically depicted using target sociogram technique. Sociometric score, Percentage and Cumulative Percentage were calculated. Seven key communicators were identified by the sample respondents, of which three were grouped under low communicators category, followed by two each in medium and high communicator categories. Two high communicators with cumulative percentages 100.00 and 78.89 occupied the central circle indicating the power of influence with respect to dissemination of agricultural information. Two medium communicators with cumulative percentages 61.11 and 38.89 occupied the second circle from the centre. Three low communicators with cumulative percentages 22.50, 10.56 and 0.83 occupied the third circle from the centre\nKeyword: Sociometry; Sociogram; Key communicator;", "pred_label": "__label__POS", "pred_score_pos": 0.9697542786598206} +{"content": "In this post, I discuss an energy storage model to analyze the energy arbitrage potential in a day-ahead electricity market. Energy arbitraging takes advantage of the price variations in the market where energy is bought at low prices and sold at high prices, thereby producing a profit. However, the profit depends on several factors, such…\nOn the 8th of January 2021, the system separation incident in Continental Europe started with the tripping of a line in Croatia due to overcurrent protection. The subsequent shift of the power flow overloaded the neighboring lines and caused them to trip as well. These cascading events are undoubtedly very critical for power systems. This…", "pred_label": "__label__POS", "pred_score_pos": 0.5317627787590027} +{"content": "Abstract\nPurpose We investigated the autofluorescence (AF) signature of the microscopic features of retina with age-related macular degeneration (AMD) using 488 nm excitation. Methods The globes of four donors with AMD and four age-matched controls were embedded in paraffin and sectioned through the macula. Sections were excited using a 488 nm argon laser, and the AF emission was captured using a laser scanning confocal microscope (496-610 nm, 6 nm resolution). The data cubes were then analyzed to compare peak emission spectra between the AMD and the controls. Microscopic features, including individual lipofuscin and melanolipofuscin granules, Bruch's Membrane, as well macroscopic features, were considered. Results Overall, the AMD eyes showed a trend of blue-shifted emission peaks compared with the controls. These differences were statistically significant when considering the emission of the combined RPE/Bruch's Membrane across all the tissue cross-sections (p = 0.02). Conclusions The AF signatures of ex vivo AMD RPE/BrM show blue-shifted emission spectra (488 nm excitation) compared with the control tissue. The magnitude of these differences is small (~4 nm) and highlights the potential challenges of detecting these subtle spectral differences in vivo.\nASJC Scopus subject areas Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) General", "pred_label": "__label__POS", "pred_score_pos": 0.8640758991241455} +{"content": "The survey aimed at evaluating the quality of selected antimalarials in sixcountries of sub-Saharan Africa (Cameroon, Ethiopia, Ghana, Kenya, Nigeria and the United Republic of Tanzania).These countries have been supported by WHO to strengthen their regulatory controls over antimalarialproducts. The survey was organized independently of manufacturers of antimalarial medicines...Of 306samples selected for laboratory testing, 267 were fully tested and 28.5% of themfailed to comply with specifications. Although non-compliance with pre-established criteriacannot be directly related to a risk for patients' health, such a high failure rate indicates a substantial problemin the quality of antimalarials present in distribution channels. Focusing only on extreme deviations fromspecifications (as defined in this report), which are likely to be associated with health implications, the failurerate reached 11.6%...", "pred_label": "__label__POS", "pred_score_pos": 0.8364843726158142} +{"content": "English español\nPlease use this identifier to cite or link to this item:\nhttp://hdl.handle.net/10261/116078\nShare/Impact:\nStatistics SHARE CORE MendeleyBASE Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE\nDC Field Value Language dc.contributor.author Zamora, Rosario - dc.contributor.author Navarro, José Luis - dc.contributor.author Aguilar, Isabel - dc.contributor.author Hidalgo, Francisco J. - dc.date.accessioned 2015-06-02T12:08:31Z - dc.date.available 2015-06-02T12:08:31Z - dc.date.issued 2015 - dc.identifier doi: 10.1016/j.foodchem.2014.11.034 - dc.identifier issn: 1873-7072 - dc.identifier.citation Food Chemistry 174: 89- 96 (2015) - dc.identifier.uri http://hdl.handle.net/10261/116078 - dc.description.abstract © 2014 Elsevier Ltd. All rights reserved. Nucleophilic degradation produced by reactive carbonyls plays a major role in food quality and safety. Nevertheless, these reactions are complex because reactive carbonyls are usually involved in various competitive reactions. This study describes the thermal degradation of 2-alkenals (2-pentenal and 2-octenal) and 2,4-alkadienals (2,4-heptadienal and 2,4-decadienal) in an attempt to both clarify the stability of aldehydes and determine new compounds that might also play a role in nucleophile/aldehyde reactions. The obtained results showed that alkenals and alkadienals decomposed rapidly in the presence of buffer and air to produce formaldehyde, acetaldehyde, and the aldehydes corresponding to the breakage of the carboncarbon double bonds: propanal, hexanal, 2-pentenal, 2-octenal, glyoxal, and fumaraldehyde. The activation energy of double bond breakage was relatively low (∼25 kJ/mol) and the yield of alkanals (10-18%) was higher than that of 2-alkenals (∼1%). All these results indicate that these reactions should be considered in order to fully understand the range of nucleophile/aldehyde adducts produced. - dc.description.sponsorship This study was supported in part by the European Union (FEDER funds) and the Plan Nacional de I + D of the Ministerio de Economía y Competitividad of Spain (project AGL2012-35627). - dc.publisher Elsevier - dc.rights openAccess en_EN dc.subject Lipid oxidation - dc.subject Food flavours - dc.subject Aldehyde degradation - dc.subject 2-Alkenals - dc.subject 2,4-Alkadienals - dc.subject Alkanals - dc.title Lipid-derived aldehyde degradation under thermal conditions - dc.type artículo - dc.identifier.doi http://dx.doi.org/10.1016/j.foodchem.2014.11.034 - dc.embargo.terms 2016-05-01 - dc.date.updated 2015-06-02T12:08:31Z - dc.description.version Peer Reviewed - dc.language.rfc3066 eng - Appears in Collections: (IG) Artículos Files in This Item:\nFile Description Size Format Postprint_FoodChem_2015_V174_P89.pdf 750,03 kB Adobe PDF\nView/Open", "pred_label": "__label__POS", "pred_score_pos": 0.9043181538581848} +{"content": "Quantitation and biochemical characterization of autophagy's role in aging Autophagy, a highly conserved intracellular protein-, lipid-, and organelle-degradation pathway, has been implicated in prolonging longevity and forestalling aging and age-related diseases including neurodegeneration, cardiomyopathy, diabetes, and cancer. This process involves the sequestration of cytosolic components within a double-membrane vesicle, the autophagosome, and the subsequent delivery of the cargo to the lysosome/vacuole where it is degraded. Once thought to nonspecifically degrade and recycle cytosolic components, more recent work has revealed that specific cargos are subject to autophagic degradation, including protein aggregates, ribosomes, mitochondria and select cytosolic proteins. Genetic knockouts targeting integral autophagy genes have demonstrated links between the aforementioned diseases, longevity/lifespan and autophagic capacity. However, the importance of nonspecific autophagy and the various forms of specific autophagy in relation to aging is currently underexplored. This work aims to quantitatively characterize the flux of these classes of autophagy with age. These experiments will utilize advanced pulse-labeling mass spectrometry techniques that I have recently developed to precisely quantify autophagic degradation globally in the model organisms S. cerevisiae and C. elegans. These data will identify selective autophagic pathways that are misregulated as cells age, providing novel targets for future pharmacological intervention in age-related disorders. Critically, the mentored phase of this work will provide essential training in the biology of autophagy and aging as well as guidance in working with model systems of aging/longevity (i.e. C. elegans and S. cerevisiae). This training will complement my extensive prior training in biochemistry, biophysics, and computational biology, thus facilitating my transition to independence. Throughout this critical transitional phase, I will receive mentoring and guidance from a distinguished committee of autophagy, aging, and biochemistry experts. Many have hypothesized that selective autophagic cargos are targeted for degradation using specific receptor proteins. However, only a few such proteins have been identified. During the independent phase, I aim to biochemically identify and characterize receptor proteins required for specific forms of aging-related autophagy identified above. Finally, the mechanisms by which autophagic capacity decreases with age are unknown. I will apply recently developed, innovative pulse-labeling mass spectrometry approaches to measure the detailed kinetics of autophagy in aging cells, thereby identifying the biochemical reaction limiting overall autophagic flux. Identification of these receptors and rate-limiting reactions will provide novel targets for he future development of therapeutics to treat age-related, autophagy-dependent diseases.\nIn all eukaryotes, the removal of harmful protein aggregates, dysfunctional organelles and the general maintenance of cellular protein homeostasis depends on autophagy, a highly-conserved degradation pathway. Through an unknown mechanism, autophagy is thought to decrease in capacity as organisms age, and this attenuation has been correlated with age-related diseases including neurodegeneration, cardiomyopathy, and cancer. This research aims to precisely quantify how autophagy changes with age, identify proteins responsible for targeting intracellular material for degradation, and uncover biochemical reactions that limit autophagic activity in aging cells; these data will be critical in the future development of therapeutics targeting age-related, autophagy-dependent diseases.\nDavis, Joseph H; Williamson, James R (2017) Structure and dynamics of bacterial ribosome biogenesis. Philos Trans R Soc Lond B Biol Sci 372: Tan, Yong Zi; Baldwin, Philip R; Davis, Joseph H et al. (2017) Addressing preferred specimen orientation in single-particle cryo-EM through tilting. Nat Methods 14:793-796 Davis, Joseph H; Tan, Yong Zi; Carragher, Bridget et al. (2016) Modular Assembly of the Bacterial Large Ribosomal Subunit. Cell 167:1610-1622.e15", "pred_label": "__label__POS", "pred_score_pos": 0.8053002953529358} +{"content": "There's a more efficient way to harvest energy from the backyard than by wiring up hapless critters. Researchers at the University of Georgia have proof: they've discovered a way to generate electricity from plants through hijacking the photosynthesis process. By altering the proteins inside a plant cell's thylakoids, which store solar energy, scientists can intercept electrons through a carbon nanotube backing that draws them away before they're used to make sugar. While the resulting power isn't phenomenal, it's still two orders of magnitude better than previous methods, according to the university. The protein modification method may have a rosier future, as well: the team believes that it could eventually compete with solar cells, producing green energy in a very literal sense.\nUniversity of Georgia stops plant photosynthesis to generate solar power Sponsored Links All products recommended by Engadget are selected by our editorial team, independent of our parent company. Some of our stories include affiliate links. If you buy something through one of these links, we may earn an affiliate commission.", "pred_label": "__label__POS", "pred_score_pos": 0.780674934387207} +{"content": "* Costa Rica’s finance ministry has confirmed that formal conversations with the International Monetary Fund (IMF) will begin on 11 January regarding an agreement for an Extended Fund Facility (EFF) to address the impact of the coronavirus (Covid-19) pandemic. According to the finance ministry, the conversations will “\naddress policies that the country needs to guarantee the sustainability of its public finances in the medium and long term, and support inclusive and sustainable growth”. In September 2020, Costa Rica’s President Carlos Alvarado presented the government’s first proposal to begin negotiating a US$1.75bn three-year financial assistance programme with the IMF. However, this proved hugely contentious due to the inclusion of proposed tax rises. After nationwide protests, the government was forced to rescind this proposal and come up with alternatives. In its latest (1 December 2020) report, the Organisation for Economic Co-operation and Development (OECD) forecast that Costa Rica’s GDP would contract by 5.6% in 2020. The OECD noted that this contraction has led to a significant loss of government revenue, exacerbating an “ already vulnerable fiscal situation”. It expected the fiscal deficit to widen to around 9.5% GDP in 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.9992911219596863} +{"content": "With the deepening of the global financial markets and the expansion of multinational corporations worldwide, corporate governance through and by the board has remained a constant focus of regulatory and academic inquiry. To deter increasingly powerful chief executives’ power, rent-extraction through ever-increasing compensation, and myopia, regulators have sought to empower the board of directors through regulations that favour greater board independence. Scholars have documented that such regulatory actions have increased shareholders’ wealth, perhaps a rare instance of regulatory success. Due to these regulatory actions and a growing shareholder awareness about the benefits of a strong oversight by independent directors, we document, in our new paper, a systematic decline in the proportion of insider directors within the board—that is, until some countries experienced a significant financial crisis. Figure 1 shows that the declining worldwide trend in the proportion of board insiders reversed only for those countries that experienced the spill-over effect of the 2008-2010 global financial crisis (GFC), which we measure using aggregate earnings shocks (AES). However, this reversal did not extend to firms in the countries that did not experience significant AES. It suggests that the country-level economic and financial uncertainty caused by the GFC directly affects how boards are constructed worldwide.\nFigure 1:How the proportion of board insiders changed in listed firms in countries that significantly experienced the 2008-2010 financial crisis through Aggregate Earnings Shocks (AES). The control sample is the firms in countries that did not experience significant AES.\nThis also brings us to why board insiders still occupy over one-third of the worldwide board seats. If we exclude CEOs from this calculation, non-CEO insiders occupy a quarter of the board seats globally. Prior research has argued that board insiders bring ‘private information,’ which is likely helpful for board decision-making processes. However, the non-CEO insiders are at serious risk of co-option and other types of undue chief executive influence, which could deter effective executive monitoring leading to board capture.\nOur study advances an argument based on the corporate socialization theory that board insiders, including the non-CEOs, bring a unique form of non-fungible expertise to the board. Fungible expertise is a type of experience and expertise common to an industry or a profession. Financial expertise, or experience within an industry, are common types of fungible expertise. For example, suppose an executive leaves their firm and joins a rival firm. Their industry experience and expertise are likely to benefit their new firm even if it would take time for that executive to get familiarized with their new firm’s corporate culture and operating processes. In contrast, non-fungible expertise is firm-specific, unique, and hard to gain without a long-tenured and focused experience within a firm. An executive can only gain non-fungible knowledge, experience, and expertise about the firm by staying employed there, knowing its people and processes, and other markers of corporate culture that are unique to it. It is potentially the source of the ‘private information’ that prior research has discussed. Consistent with this theory, we document that when listed firms in some countries experienced a significant financial crisis, they appointed\nlong-tenured and firm-focused non-CEO board insiders. Here, long-tenured insiders are those executives who have long-run experience within the firm. Moreover, firm-focused are the insiders who do not have any other outside affiliations apart from their firm, which would allow them to keep their ears-to-the-ground. We further document that financially distressed firms, ie, firms with more than two years of consecutive negative market returns, have a stronger demand for these types of non-CEO board insiders.\nWhile the financial crisis allowed us to study the non-CEO board insiders’ selection mechanism closely, it raises several concerns for the regulators, academics, and shareholders. During the previous wave of regulatory interventions, policy-makers focused on board independence. However, in the post-financial crisis period, many countries’ regulatory focus has been on the demographic aspects of the board (see Table 1). As we document in our study, this focus has led to a significant increase in non-CEO board insiders’ representation in firms that experienced a financial crisis. Therefore, regulators and other stakeholders must explore to what extent the board configuration favouring the non-CEO board insiders with non-fungible expertise is ‘good’ for the firms and if it helps increase shareholders’ wealth, especially during periods of great economic and financial uncertainty. Else, there needs to be a renewed focus on board independence, especially in countries that experienced a significant financial crisis. This call is especially urgent given the new global macro shock in the form of the COVID-19 pandemic and its economic and financial aftereffects, which are also likely to affect firms and their governance structures in unknown ways.\nShibashish Mukherjee is an Assistant Professor in Corporate Finance at EMLYON Business School, France. Jelle Bonestroo is a Finance Professional.", "pred_label": "__label__POS", "pred_score_pos": 0.9810751080513} +{"content": "COVID-19 IMPACT ANALYSIS\nTimely market intelligence is paramount in these uncertain times!\nMarket Size numbers with existing Pre-COVID scenario compared with Post COVID scenario\nForecasts predicted based on post-COVID scenario\nTrends, drivers and challenges including impacts of COVID scenario\n1 HOUR FREE ANALYST TIME:\nSpeak directly to the research team to clarify any post purchase queries you may have.\nP.S The current version of the report will be delivered immediately. The new version with the COVID-19 Impact Analysis will be delivered within 3 business days.\nAbout Paddlesports Equipment\nThe global paddle sports equipment market includes rafting, standup paddle boarding, and canoeing and kayaking equipment. The market is expected to grow due to the advances in technology, which improve the features of these products, thereby enhancing their performance.\nTechnavio’s analysts forecast the global paddlesports equipment market to grow at a CAGR of 12.87% during the period 2017-2021.\nCovered in this report\nThe report covers the present scenario and the growth prospects of the global paddlesports equipment market for 2017-2021. To calculate the market size, the report presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources.\nThe market is divided into the following segments based on geography:\n- Americas\n- Europe\n- ROW\nTechnavio's report, Global Paddlesports Equipment Market 2017-2021, has been prepared based on an in-depth market analysis with inputs from industry experts. The report covers the market landscape and its growth prospects over the coming years. The report also includes a discussion of the key vendors operating in this market.\nKey vendors\n- AIRE\n- BIC Sport\n- HYSIDE Inflatables\n- NRS\n- SOTAR\nOther prominent vendors\n- Aqua Marina\n- Kwik Tek\n- Malibu Kayaks\n- Johnson Outdoors\n- RAVE Sports\n- Vanguard Inflatables\nMarket driver\n- Rising interest in soft adventure sports activities.\n- For a full, detailed list, view our report\nMarket challenge\n- High cost of paddle sports equipment.\n- For a full, detailed list, view our report\nMarket trend\n- Fitness benefits associated with paddle sports.\n- For a full, detailed list, view our report\nKey questions answered in this report\n- What will the market size be in 2021 and what will the growth rate be?\n- What are the key market trends?\n- What is driving this market?\n- What are the challenges to market growth?\n- Who are the key vendors in this market space?\n- What are the market opportunities and threats faced by the key vendors?\n- What are the strengths and weaknesses of the key vendors?\nYou can request one free hour of our analyst’s time when you purchase this market report. Details are provided within the report.\nMethodology\nResearch methodology is based on extensive primary and secondary research. Primary research includes in-depth interviews with industry experts, vendors, resellers and customers. Secondary research includes Technavio Platform, industry publications, company reports, news articles, analyst reports, trade associations and the data published by Government agencies.", "pred_label": "__label__POS", "pred_score_pos": 0.9421437382698059} +{"content": "This study used a phenomenological approach, founded on the Husserlian tradition, to discover the spiritual essence of palliative care in the lived experience of stakeholders. Semistructured interviews were conducted with 16 participants who held a variety of roles linked to palliative care, and were of different religions and none. Amongst these participants, spiritual care is based on the assumption that all people are spiritual beings. It recognizes the relationship between illness and the spiritual domain and acknowledges the possibility of a search for meaning in the big questions of life and death. It responds to religious and humanistic needs by meeting both the requirements of faith and the desire for another human being to ‘be there’. Fundamentally, spiritual care seeks to affirm the value of each and every person based on nonjudgemental love.", "pred_label": "__label__POS", "pred_score_pos": 0.5506013631820679} +{"content": "The U.S. Department of Health and Human Services (HHS) has extended the Medicaid and Children’s Health Insurance Program (CHIP) Provider Relief Fund application deadline to Aug. 3.\nHHS first opened applications for the COVID-19 relief funds in June. The agency plans to distribute approximately $15 billion to eligible providers that participate in state Medicaid and CHIP programs and have not yet received a payment from the $50 billion General Distribution to Medicare providers. Both funds are part of the Coronavirus Aid, Security and Economic Security (CARES) Act.\n— Kent Moore, Senior Strategist for Physician Payment at the American Academy of Family Physicians\nSign up to receive\nFPM's free, weekly e-newsletter, \"Quick Tips & Insights,\" featuring practical, peer-reviewed advice for improving practice, enhancing the patient experience, and developing a rewarding career.\nDisclaimer: The opinions and views expressed here are those of the authors and do not necessarily represent or reflect the opinions and views of the American Academy of Family Physicians. This blog is not intended to provide medical, financial, or legal advice. Some payers may not agree with the advice given. This is not a substitute for current CPT and ICD-9 manuals and payer policies. All comments are moderated and will be removed if they violate our Terms of Use.", "pred_label": "__label__POS", "pred_score_pos": 0.8630800843238831} +{"content": "ACO Rankings Team\nOur proprietary methodology for evaluating college programs helps eliminate bias from our guides and rankings. The data sources we use, which include the National Center for Education Statistics, the Common Data Set Initiative, and Peterson’s, are all recognized for providing accurate information about education and occupations around the United States.\nWe may also collect our own data through online surveys when we believe such data would provide a more complete and valuable experience for the user in making a college selection. In addition to maintaining the highest standards for our sources, we use the following guidelines to ensure we remain impartial and independent in our content:\n- We do not rank schools or programs based on any type of financial relationship with a school partner. - Schools never receive preferential treatment. - For each of our core rankings, we evaluate all schools using the same criteria, awarding total scores that reflect the hard data. - We only assign ranking scores that directly reflect variables such as admission rates, retention rates, and program costs.\nWe take editorial integrity seriously and are constantly evaluating our content for bias, recency, and accuracy. Our writers, editors, and reviewers all abide by a consistent set of editorial standards. These standards help ensure responsible journalism and the balanced presentation of facts.\nAll schools in our degree rankings are nationally or regionally accredited, providing an extra layer of quality assurance and transparency in our rankings.\nEditorial Guidelines\nOur team is dedicated to giving you expert-driven, data-backed information covering education. At AffordableCollegesOnline, all pages are fact-checked by professionals and follow strict guidelines to ensure that content is timely, accurate, and free from bias. Read more about our process.", "pred_label": "__label__POS", "pred_score_pos": 0.9315209984779358} +{"content": "Today we conclude 34 consecutive days of prayer for the\n10/40 Window, especially for nations in conflict. If you’ve been praying with us, thank you, and for continuing to uphold this region before God. We know that, uniting in prayer, we can make a difference.\nOn September 21 each year the world observes the\nInternational Day of Peace. It’s a day for ceasefire – personal or political. People mark it by joining events, lighting a candle, releasing a caged animal or planting a tree. Lockdown restrictions may affect what you do, but we can all observe the Minute of Silence at noon local time . This ‘peace wave’ rolls across the globe for 1436 consecutive minutes, as peoples of the world contemplate living in harmony.\nIt’s a UN ideal that nations in conflict will cease hostilities for at least this day, and take the opportunity to negotiate peace. It’s hard to say how often such truce is observed – but as we know from Christmas 1914, miracles do happen. We can ask God to intervene, and bring a resolution for suffering populations.\nFor he himself is our peace, who has made the two groups one and has destroyed the barrier, the dividing wall of hostility, by setting aside in his flesh the law with its commands and regulations. Ephesians 2: 14-15\nThis special day is also a great opportunity to lay down arms in our personal lives. We are reminded that we are not each other’s enemy. That we must make peace with one another. And that we must unite against acts of hate by spreading compassion, kindness and hope. As a UN Secretary General once said, “Peace requires work – long, hard, difficult work.”\nToday, could you take a step towards making peace, in your own situation? Perhaps you could start by praying about it, as you observe the Minute of Silence at noon.\nAim for restoration, comfort one another, agree with one another, live in peace; and the God of love and peace will be with you. 2 Cor 13: 11", "pred_label": "__label__POS", "pred_score_pos": 0.639004111289978} +{"content": "Article by: Cory D. N. Greenleaf\nOn March 24, 2021, the New Hampshire Supreme Court issued an opinion, In re Greenberg, to decide the issue of whether a father was required to pay additional child support to the mother after obtaining shares of vested restricted stock from his employer.\nThe parties entered into a final divorce decree in December 2015. The decree stated that the father would pay “28% of any bonus he may receive [from his employer] within 3 days of receipt” in addition to regularly monthly child support. The decree awarded the father “any stock options” he received from his employer free from the mother’s interest. The father’s employer, a publicly traded company, awarded him 5,000 shares of stock in June 2015. None of the shares had vested at the time of the 2015 divorce.\nAs of 2019, the father netted a total of $324,856.63 following the sale of his vested restricted stock. The Internal Revenue Service treated the stock as taxable income. The father did not include the shares in his Financial Affidavit to the court, nor did he inform the mother regarding the sale of his restricted shares or pay any of the proceeds as child support.\nIn May 2019, the mother motioned to modify child support based on a suspicion that the father had a significant increase in wealth since the divorce decree became final in 2015. The trial court determined that, in accordance with the 2015 divorce decree, the father was obligated to pay $90,959.58, which represented 28% of his $324,856.63 derived from the sale of his vested stock.\nOn appeal, the father argued that, because he has not yet liquidated his restricted shares, it cannot count as “income” for child support purposes. While the Court agreed that assets, like shares of stock, are not considered “income” for the purposes of calculating child support pursuant to N.H. RSA § 458-C:3, the Court reasoned that liquidity is not conclusive as to whether something is characterized as an “asset” or as “income” for child support purposes. The Court determined that the father’s stock awards are part of his employee compensation package and are reportable income for child support calculation purposes, despite whether or not he sold the stock. The stock awards, according to the Court, operate like a “bonus” with taxable value and meet the statutory definition of “income” for child support.\nThe Court affirmed the lower court’s findings and ruled that the father was required to pay $90,959.58 in overdue child support to the mother.", "pred_label": "__label__POS", "pred_score_pos": 0.914172887802124} +{"content": "To be present is to be in a state of consciousness where you are fully aware of your own mind and what is behind your thought processes in this moment, in this place. It is to accept the present, without worrying about the past or the future. Many center their spiritual practices to practice living in the moment, as it is the only moment in which we are alive, as a way to be closest to the Divine. Others use focusing on the present as a way to alleviate anxiety, stress, and grief. Still others use their practice to connect better with others and practice with others. Whatever your motivation, there are many approaches to practicing being present.", "pred_label": "__label__POS", "pred_score_pos": 0.5041854977607727} +{"content": "Don't Skip Steps in the Sequence of a Proper Ask\nI asked the nonprofit exec to do a lot of listening in his next several meetings with potential donors. Perhaps not even ask them for a gift at all — at least this time. Listen for the cues that tell you what the individual is thinking, what he knows and, more importantly, what he doesn't know. Once you know where the gaps in the potential donor's understanding are, you can adroitly bridge them and move the donor to an emotional commitment, which is the precursor for a financial investment.\nI haven't yet heard back from Tom, but I'm eagerly awaiting a progress report. I extend my thanks to him for reaching out and being wiling to honestly explore how he can become a more effective advocate and fundraiser for his worthy organization. A copy of \"The Eight Principles of Sustainable Fundraising\" is on it's way to Tom as my thank you.\nPlease let me hear from you concerning your particular situation and the difficulties you face in developing sustainable revenue streams. Email me. and I'll give you a quick response. I'll choose some of these thorny obstacles to share, along with my insights, in upcoming columns. Larry C. JohnsonAuthor's page\nAn internationally recognized philanthropy and fundraising thought leader, Larry C. Johnson trains the staff and volunteers of worthy causes to achieve real impact through the creation of reliable, growing revenue streams. He emphasizes principles before methods as the key to long-lasting success. He stresses the simple, the practical and the joyful.\nLarry is the founder of The Eight Principles, the premier brand for educational products and services in relational fundraising and philanthropy. The Eight Principles provides digital education, live workshops and structured coaching to nonprofit organizations.\nAuthor of the award-winning book, \"The Eight Principles of Sustainable Fundraising,\" AFP named Larry Outstanding Development Executive in 2010. The Wall Street Business Network ranks him in the Top 15 Fundraising Consultants in the USA. Larry is a graduate of Yale University. Larry speaks widely and serves on numerous nonprofit and corporate boards, including The Philanthropy Council of The Carter Center, the philanthropy of the 39th President of the U.S.", "pred_label": "__label__POS", "pred_score_pos": 0.5127319097518921} +{"content": "The process for each mold remediation can vary drastically depending on the damage. However, there are a few basic steps that are generally followed. Here is what you can expect to take place during your restoration work.\n1. Vacuum the Water The first step will involve using shop vacuums to suck up the water in your building. This removes the standing water from your floors and other hard surfaces. However, it will not remove moisture from porous materials, such as drywall. Instead, they will only spread mold spores from damp materials like this. Afterward, the vacuums will be thoroughly cleaned and sanitized. 2. Clean Surfaces This fungus is not something you want to be left on your surfaces. Therefore, the next step is to scrub nonporous surfaces with water and a detergent. Then, they will be allowed to dry. Note, workers will clean only nonporous materials. Porous items will likely need to be thrown away. This is because spores can get trapped in the pores and become nearly impossible to remove. 3. Use a HEPA Vacuum After everything has been cleaned and dried, the next step is to use a High-Efficiency Particulate Air vacuum inside the area that cleanup professionals have sectioned off. Workers should use the vacuum to remove dust and other particulates. They must use a HEPA vacuum with the filter correctly installed. Additionally, this can disrupt spores, so it is important to wear PPE while performing this step. Once finished, the filter and vacuum contents must be safely disposed of. 4. Remove Damaged Materials Finally, any building materials that are not salvageable must be removed from the containment area safely. Generally, this means bagging them in thick plastic and discarding them as construction materials. However, they must remain sealed in the bags to reduce the spread of spores. Items that are too large for bags should have plastic sheets wrapped around them and sealed with duct tape before removal. While the mold restoration process is not always the same, these are the basic steps that will take place. By following these, contractors ensure they remove the spores completely and safely.", "pred_label": "__label__POS", "pred_score_pos": 0.9945148825645447} +{"content": "This study investigates changes in specific behavioural patterns following a series of non-directive serial sandplay sessions with boys aged five-six years demonstrating oppositional defiant behaviours in the classroom, as defined in section F91.3 of the ICD-10 and 313.81 of the DSM-IV-TR.\nThis is a small scale qualitative systematic hermeneutic study supported by quantitative data. The research sample consists of five Caucasian boys attending a primary school in a small town situated in North West England. The boys were selected by using questions 21-28 of the SNAP IV Rating Scale.\nFour assessment methods were used these are; Continual evaluations of sandplay sessions and symbolic interpretation; House-Tree-Person Assessment; Strengths and Difficulties Questionnaires; and a Five Trait Rating Scale.\nThe results demonstrate a correlation between all four assessment tools for four out of the five children indicating a reduction of oppositional defiant behaviours. The fifth child did not show improvement, however a plausible explanation has been provided for his results.\nThe results indicate that a series of non-directive sandplay sessions with boys aged 5-6 years can reduce their oppositional defiant behaviours in the classroom. Changes in the boys behaviour are reflected by their level of engagement and expression in the sandtrays.\nThe results indicate that further research over an extended period of time is required.", "pred_label": "__label__POS", "pred_score_pos": 0.9232978820800781} +{"content": "The phrase 'the elephant in the room' is often used yet it's impact is less frequently talked about. Sure we can all play along acknowledging the 'elephant' but not discussing it. However I wonder what impact this elephant ignoring has on growing companies?\nHere are some examples I've seen recently:\nthe CEO who can't raise funds for a great company because he's not investor credible the founder who can't grow with the business and is holding growth back the avoidance of difficult conversations around performance.\nI am sure you too have elephants you know. So whose interest are we protecting? What Is the worst thing that could happen if we maturely and honestly discussed the 'elephant'? What might be the good outcomes? What will be the impact on business growth? Even the elephant might thank us!", "pred_label": "__label__POS", "pred_score_pos": 0.5234384536743164} +{"content": "Longer lives bring opportunities to prolong careers, participate in new activities, explore interests and contribute to society. Lena Gan, a PhD. Student at the University of Melbourne, is undertaking research to better understand the potential of this link and is seeking Friends of Te Papa members aged between 45 – 95 years to participate.\nRead more\n|September 24, 2018", "pred_label": "__label__POS", "pred_score_pos": 0.9350149631500244} +{"content": "FDA approves Prograf to prevent organ rejection in lung transplant recipients\nThe FDA has approved the immunosuppressant drug tacrolimus to prevent rejection in adult and pediatric patients who receive lung transplants, according to a press release.\nTacrolimus (Prograf, Astellas Pharma) is the only immunosuppressant drug for this population, according to the release.\nPrograf was originally approved to prevent organ rejection in patients receiving liver transplants and was later approved to prevent organ rejection for kidney and heart transplants. The drug has also been routinely used in clinical practice for patients receiving lung transplants, according to the release.\nTh new approval was based on an observational study that provided real-world evidence of the effectiveness of tacrolimus to prevent organ rejection in adults and children undergoing lung transplantation. The noninterventional study supporting approval for the new indication used real-world data from the U.S. Scientific Registry of Transplant Recipients, supported by the Department of Health and Human Services. Data were collected on all lung transplants in the U.S. and were supplemented by mortality data from the Social Security Administration’s Death Master File. Researchers observed a dramatic improvement in outcomes among lung transplant recipients who received tacrolimus as part of their immunosuppression medications compared with the well-documented natural history of a transplanted drugs with no or minimal immunosuppressive therapy, according to the release.\nIn addition, evidence from randomized controlled trials of tacrolimus used in other solid organ transplant settings provided evidence of effectiveness and clinical trial evidence from research publications support tacrolimus as part of a multidrug immunosuppressive regimen, according to the release.", "pred_label": "__label__POS", "pred_score_pos": 0.7412688732147217} +{"content": "Social media marketing provides companies with a way to engage with existing customers and reach new ones while allowing them to promote their desired culture, mission, or tone.\nUnderstanding the functional building blocks of social media\", researchers provide a framework that defines social media, which includes seven functional social media building blocks: identity, conversations, sharing, presence, relationships, reputation, and groups.\nSocial media networks are open to all, giving businesses a chance to follow their consumers' activities or potential buyers. This helps marketers be more informed about their target audience, likes, dislikes, and interests so that they can create a better marketing strategy to attract such customers.", "pred_label": "__label__POS", "pred_score_pos": 0.9638392925262451} +{"content": "Should farmers farm more? Comparing marginal products within Malawian households\nAccording to standard economic theory, households should equate the marginal revenue product of an input across activities within the household. However, this prediction may not hold in the presence of risk. Using data on farm plots and non-farm enterprises in Malawi, we examine the impact of risk on the allocation decisions of agricultural households as they allocate labor across farm and non-farm production. We control for many household and production characteristics, including household fixed effects, and find farm marginal revenue product of labor (MRPL) to be consistently higher than non-farm MRPL. These results are consistent with farm production being riskier than non-farm production for most households in Malawi. These findings suggest that improved access to insurance of farming activities and wage employment opportunities could increase total household income.\nClick the button and follow the links to connect to the full text. (KDI CL members only)\nItems in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.", "pred_label": "__label__POS", "pred_score_pos": 0.9099622964859009} +{"content": "The following is from another student that i have to reply.\nAPA, less than 10 % similarity\nQuestion:\nSuppose a 17-year-old male was in a sexual relationship with a female in her thirties. This is a willing relationship on both sides, perhaps even a relationship begun by the male. Now, if the genders were reversed and the male was the older member of the couple, the relationship would be considered sexual assault, pure and simple. But, in a situation with an older woman/younger man:\n1. what do you think could or should be done? Anything?\n2.Should the woman be prosecuted in this case? Should the young man (a willing participant) be considered as an adult, or as still under-aged?\nThink again about the scenario as it stands, and then as it would be with reversed gender roles.\nDid your opinions change from one to the other, and if so, how? Is this a double standard?\nAnswer\nCases of sexual assault have significantly increased in many parts of the world. Notably, stereotypes, beliefs, culture, and norms are fundamental factors that have made it challenging to address sexual assault cases. For instance, in the case attached, it is evident that society has stereotyped sexual assault as a criminal act that can only be perpetrated by men. The United States’ laws have achieved a significant milestone in protecting minorities from all forms of sexual assaults (Jessup-Anger, Lopez, & Koss, 2018). Hence, under the two cases highlighted, adults should be held accountable for engaging in sexual relations with a minor.\nThe woman in the case attached has committed a serious sexual offense for agreeing to engage in a sexual relationship with a 17 years underage boy. Hence, if the court gathers sufficient evidence to prove the woman’s consent regarding the boy’s age, she will be prosecuted for deliberately assaulting a minor. Many societies hold that men have the jurisdiction to make informed sexual choices and decisions regardless of age (Spohn, 2020). As a result, the notion has significantly hindered the efforts to protect the underaged boys from intentional sexual assaults.\nThe adequate sensitization of society about the nature, causes, and effects of sexual assaults, especially regarding minors, is one of the basic strategies that can be used to initiate equality in the protection of underage boys and girls. Besides, it is paramount to eliminate the impartiality in determining cases regarding the assault of both boys and girls (Swan, 2020). Notably, the United States’ laws perceive minors as incapable of making accurate and informed decisions. Hence, adults and the laws must protect underage boys and girls from all forms of sexual assaults.\nReferences\nJessup-Anger, J. E., Lopez, E., & Koss, M. P. (2018). History of sexual violence in higher education.\nNew Directions for Student Services.\nSpohn, C. (2020). Sexual assault case processing: The more things change, the more they stay the same.\nInternational journal for crime, justice, and social democracy, 9(1), 86.\nSwan, S. L. (2020). Discriminatory Dualism in Process: Title IX, Reverse Title IX, and Campus Sexual Assault.\nOkla. L. Rev., 73, 69.", "pred_label": "__label__POS", "pred_score_pos": 0.8559767007827759} +{"content": "DC Field Value Language dc.contributor.author Heo, Kyungmoo ko dc.contributor.author Seo, Yongseok ko dc.date.accessioned 2021-08-03T00:30:06Z - dc.date.available 2021-08-03T00:30:06Z - dc.date.created 2021-08-03 - dc.date.created 2021-08-03 - dc.date.created 2021-08-03 - dc.date.issued 2021-12 - dc.identifier.citation EUROPEAN JOURNAL OF FUTURES RESEARCH, v.9, no.1 - dc.identifier.issn 2195-4194 - dc.identifier.uri http://hdl.handle.net/10203/286951 - dc.description.abstract Anticipatory governance (AG) is defined as a \"system of systems\" that employs foresight to create future plans and execute relevant actions. Recently, various frameworks of AG have been introduced, but there is little practical information available for newcomers on how to do this. This research conducted a framework-based comparative country analysis to provide lessons learned for newcomers in the sphere of foresight-linked AG. By evaluating the AG levels of Finland, the UK, the Netherlands, and Korea, we found that the consequences of foresight-linked AGs were different in each country. At the same time, we also identified a common denominator, namely, future receptivity, a \"human or people\" capacity to accept and understand the value of foresight. Instead of temporary system changes or organizational modifications, future receptivity is an underlying element for newcomers to overcome lingering short-termism and facilitate the coordination of stakeholders concerning foresight. In conclusion, we suggest ways to promote future receptivity for newcomers. First, the government should educate and train the public and government officials to promote future literacy and future proficiency. Second, the government should provide a process for public participation such as nationwide networking that enables the public to influence their diverse future images over foresight outcomes. - dc.language English - dc.publisher SPRINGER - dc.title Anticipatory governance for newcomers: lessons learned from the UK, the Netherlands, Finland, and Korea - dc.type Article - dc.identifier.wosid 000671759000001 - dc.identifier.scopusid 2-s2.0-85109796970 - dc.type.rims ART - dc.citation.volume 9 - dc.citation.issue 1 - dc.citation.publicationname EUROPEAN JOURNAL OF FUTURES RESEARCH - dc.identifier.doi 10.1186/s40309-021-00179-y - dc.contributor.localauthor Heo, Kyungmoo - dc.contributor.localauthor Seo, Yongseok - dc.description.isOpenAccess N - dc.type.journalArticle Article - dc.subject.keywordAuthor Anticipatory governance - dc.subject.keywordAuthor Capacity building - dc.subject.keywordAuthor Future receptivity - dc.subject.keywordAuthor Newcomer - dc.subject.keywordAuthor Public participation - dc.subject.keywordPlus POLICY - dc.subject.keywordPlus FORESIGHT - dc.subject.keywordPlus FUTURES - dc.subject.keywordPlus ANTHROPOLOGY - dc.subject.keywordPlus IMPACTS - dc.subject.keywordPlus WORLD -", "pred_label": "__label__POS", "pred_score_pos": 0.9995460510253906} +{"content": "Solar photovoltaic technology for small-scale irrigation in Ghana: suitability mapping and business models\nThis report assesses the potential of solar photovoltaic (PV) irrigation for smallholder agriculture in Ghana, using elements of business planning and business models with a suitability mapping approach. These approaches take into account the economic as well as environmental sustainability of expanding such technology. Using data from existing solar PV irrigation systems and interviews with key industry actors, the report discusses the regulatory and institutional context for investment in solar PV technology and outlines the technology supply chain, mapping the key actors and their roles. The financial viability of two empirical business cases – directly funding an agribusiness and subsidizing a cooperative model – is analyzed to assess the feasibility of expanding access to the technology.", "pred_label": "__label__POS", "pred_score_pos": 0.9526442885398865} +{"content": "Navigating digital information 7\nPosted February 21, 2019on:\nThis week’s Crash Course’s video on navigating digital information focused on evaluating images and videos.\nHost John Green provided examples of how images could be used to represent and misrepresent both context and context. If it is easy to fool someone with text, it is even easier with images.\nWhen presented with any image we might verify its context and content by a) seeking its source and determining its reliability, and b) searching laterally for its validity. If links or cues are not available in a suspicious image, we might use Google’s image search or Tineye to evaluate its worth.\nHow about videos? The principles are the same: Determine the veracity of its source, the reputation of its creator(s), and whether or not is was altered. It might be difficult to do the last item nowadays, but difficult is not impossible. What works for text also works for videos — search, read, and watch laterally.", "pred_label": "__label__POS", "pred_score_pos": 0.96002197265625} +{"content": "How animals, particularly livestock, adapt to various climates and environments over short evolutionary time is of fundamental biological interest. Further, understanding the genetic mechanisms of adaptation in indigenous livestock populations is important for designing appropriate breeding programs to cope with the impacts of changing climate. Here we conducted a comprehensive genomic analysis of diversity, interspecies introgression and climate-mediated selective signatures in a global sample of sheep and their wild relatives. By examining 600k and 50k genome-wide SNP data from 3447 samples representing 111 domestic sheep populations and 403 samples from all their seven wild relatives (argali, Asiatic mouflon, European mouflon, urial, snow sheep, bighorn and thinhorn sheep), coupled with 88 whole-genome sequences, we detected clear signals of common introgression from wild relatives into sympatric domestic populations, thereby increasing their genomic diversities. The introgressions provided beneficial genetic variants in native populations, which were significantly associated with local climatic adaptation. We observed common introgression signals of alleles in olfactory-related genes (e.g., ADCY3 and TRPV1) and the PADI gene family including in particular PADI2, which is associated with antibacterial innate immunity. Further analyses of whole-genome sequences showed that the introgressed alleles in a specific region of PADI2 (chr2: 248302667-248306614) correlate with resistance to pneumonia. We conclude that wild introgression enhanced climatic adaptation and resistance to pneumonia in sheep. This has enabled them to adapt to varying climatic and environmental conditions after domestication.\nclimate adaptation genome-wide SNPs introgression ovine pneumonia whole-genome sequences", "pred_label": "__label__POS", "pred_score_pos": 0.6650478839874268} +{"content": "Background: The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex and country over recent years. Methods: We used results from the Global Burden of Disease (GBD) 2017 study to report incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years for all locations in the GBD 2017 hierarchy from 1990 to 2017 for road injuries. Second, we measured mortality-to-incidence ratios by location. Third, we assessed the distribution of the natures of injury (eg, traumatic brain injury) that result from each road injury. Results: Globally, 1 243 068 (95% uncertainty interval 1 191 889 to 1 276 940) people died from road injuries in 2017 out of 54 192 330 (47 381 583 to 61 645 891) new cases of road injuries. Age-standardised incidence rates of road injuries increased between 1990 and 2017, while mortality rates decreased. Regionally, age-standardised mortality rates decreased in all but two regions, South Asia and Southern Latin America, where rates did not change significantly. Nine of 21 GBD regions experienced significant increases in age-standardised incidence rates, while 10 experienced significant decreases and two experienced no significant change. Conclusions: While road injury mortality has improved in recent decades, there are worsening rates of incidence and significant geographical heterogeneity. These findings indicate that more research is needed to better understand how road injuries can be prevented. Keywords: burden of disease; descriptive epidemiology; motorcycle; road injuries, pedestrian injuries; road traffic accident; traumatic brain injury.\n© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.", "pred_label": "__label__POS", "pred_score_pos": 0.9151569604873657} +{"content": "Abstract\nThe melanocortin receptors (MC1R-MC5R) belong to class A G-protein-coupled receptors (GPCRs) and are known to have receptor-specific roles in normal and diseased states. Selectivity for MC4R is of particular interest due to its involvement in various metabolic disorders, including obesity, feeding regulation, and sexual dysfunctions. To further improve the potency and selectivity of MC4R (ant)agonist peptide ligands, we designed and synthesized a series of cyclic peptides based on the recent crystal structure of MC4R in complex with the well-characterized antagonist SHU-9119 (Ac-Nle4-c[Asp5-His6-DNal(2′)7-Arg8-Trp9-Lys10]-NH2). These analogues were pharmacologically characterized in vitro, giving key insights into exploiting binding site subpockets to deliver more selective ligands. More specifically, the side chains of the Nle4, DNal(2′)7, and Trp9 residues in SHU-9119, as well as the amide linkage between the Asp5 and Lys10 side chains, were found to represent structural features engaging a hMC4R/hMC3R selectivity switch.", "pred_label": "__label__POS", "pred_score_pos": 0.65586256980896} +{"content": "Longitudinal Analysis of the Utility of Liver Biochemistry as Prognostic Markers in Hospitalized Patients With Corona Virus Disease 2019. Wang T., Smith DA., Campbell C., Harris S., Salih H., Várnai KA., Woods K., Noble T., Freeman O., Moysova Z., Marjot T., Webb GJ., Davies J., Barnes E., Matthews PC.\nThe association of liver biochemistry with clinical outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is currently unclear, and the utility of longitudinally measured liver biochemistry as prognostic markers for mortality is unknown. We aimed to determine whether abnormal liver biochemistry, assessed at baseline and at repeat measures over time, was associated with death in hospitalized patients with COVID-19 compared to those without COVID-19, in a United Kingdom population. We extracted routinely collected clinical data from a large teaching hospital in the United Kingdom, matching 585 hospitalized patients who were SARS-CoV-2 real-time reverse transcription-polymerase chain reaction (RT-PCR) positive to 1,165 hospitalized patients who were RT-PCR negative for age, sex, ethnicity, and preexisting comorbidities. A total of 26.8% (157/585) of patients with COVID-19 died compared to 11.9% (139/1,165) in the group without COVID-19 (P", "pred_label": "__label__POS", "pred_score_pos": 0.8193082809448242} +{"content": "Select a Country Site\nChanging your site will take you to the URL for that ManpowerGroup location.\n\"This recovery is unlike any we have seen before with hiring intent picking up much faster than after the previous economic downturn,\" said Jonas Prising, ManpowerGroup Chairman and CEO.\n\"As vaccine rollouts gain momentum and lockdown restrictions ease in many markets, we're seeing sharp increases in hiring optimism reported by employers. At the same time, some workers are hesitant to re-engage with employers as factors including health concerns and childcare challenges continue. Continued talent shortages mean many businesses are prioritizing retaining and training workers with the skills they need to succeed as the economic recovery continues.\"\nMarkets bounce back:The strongest year-on-year improvements are reported in the Netherlands (+41%), India (+40%) and the UK (+39%). Increasing talent shortage:69% of employers globally report experiencing some difficulty filling roles due to lack of skilled talent, with the most impacted regions EMEA (73%) and APAC (72%). The Americas report the least difficulty, with 38% stating they are having no difficulty at all. Employers offering a mix of incentives to fill talent shortages:Most plan to offer greater flexibility, training, and skills development to fill vacancies, though 51% of employers are planning some form of financial offering or incentive to help attract talent, compared to 20% offering non-financial benefits such as increased number of vacation days. Barriers to upskilling: As more employers’ plan to upskill workers, 78% said something other than money was the biggest barrier preventing them from increasing or scaling upskilling programs in their organization. Technical skills and career coaching key focuses for HR teams:A quarter of employers plan to invest in accelerated upskilling in technical skills for employees, and 21% plan to employ career coaching programs in the next six months to help fill the widening talent shortage.", "pred_label": "__label__POS", "pred_score_pos": 0.7433211803436279} +{"content": "Simply put, disruptors change the formula for winning business models. For retailer marketers, digital disruption is becoming a constant. Retail marketers must now be highly flexible and adaptable, anticipating and reacting to the next round of digital disruptors. As we progress in 2015, here are five potential disruptors that all digital marketers will need to be actively engaging on to ensure they continue to have a winning formula for success:", "pred_label": "__label__POS", "pred_score_pos": 0.92090904712677} +{"content": "Worldwide, single mothers are profoundly time and income constrained, making them heavily reliant on government transfers. We examine how welfare reforms that introduced mutual obligations affected the economic position of single mothers and the development of their children over the past two decades in Australia. Using nationally representative longitudinal data, we show that disposable incomes of single-mother households were significantly reduced relative to partnered mothers since the 2005 Welfare-to-Work Act came into effect in July 2006, a downward trend that was aggravated by the Global Financial Crisis and the 2013 suspension of grandfathered single parenting payment rules. The reform diminished parenting and family payments for single mothers, who compensated income loss by increasing reliance on disability pension payments, work hours, and child-care expenditures. We then use nationally representative cohort data to estimate the impact of single motherhood on child skill development, following children who entered primary school when their mothers were affected by the Welfare-to-Work reform. We find unadjusted single-motherhood gaps of 0.2 SD in cognitive and 0.3 SD in non-cognitive skills. Non-cognitive skill gaps are only partially explained by differences in observable characteristics, while cognitive skill gaps are fully explained by observable characteristics. Differences in disposable household income between single and partnered mother households explain over 50% of the observed cognitive ability gaps in childhood and 25% in late adolescence. In the presence of positive spillover effects, we propose that welfare payments to vulnerable families may function as a social investment rather than a sunk cost.\nTitelaufnahme\nZugänglichkeit\nDas Dokument ist öffentlich zugänglich im Rahmen des deutschen Urheberrechts.\nVolltexte\nLinks\nZusammenfassung\nNutzungshinweis", "pred_label": "__label__POS", "pred_score_pos": 0.7142465710639954} +{"content": "The murders of George Floyd, Breonna Taylor, and countless others have changed the scope of political discourse within America, bringing to the forefront questions of the method by which officers are held accountable and the scope of police authority itself. However, policing does not pivot merely around the police force; it also entails the institutions which empower police to enforce, and indeed that which they are entrusted to enforce. It is in this context that counterterrorism must be examined, expanding the conversation about policing, so that fundamental questions asked about those who police at home are also asked about those who police abroad.\nIn the wake of September 11, 2001, President George W. Bush initiated the defining military campaign of the modern world: the global War on Terror, which authorized a wide array of strategies to defeat the new global specter of terrorism. This campaign, led by the United States, the United Kingdom, France, and others, has involved direct military intervention, military assistance, intelligence gathering, drone warfare, economic sanctions, domestic surveillance, diplomacy, international cooperation, and more. While counterterrorism policy is hotly debated in political cycles, the fundamental US strategy has not been meaningfully altered. Counterterrorism involves aggressively capturing or killing terrorists. It means dismantling their networks so they never rise again. The point of this article, however, is not to evaluate the success or failure of the War on Terror, speculate on a potential endgame, or engage in a debate over global counterterrorism policy. Rather, it will pose the same questions that communities across the world are asking of those entrusted to guard their safety. Simply put, who are the world's police, and more importantly, what are they empowered to do?\nThe Unitary Executive\nAn undeniable reality of the last 18 years has been the expansion of executive authority, at the expense of traditional checks and balances. The Patriot Act in the United States expanded authority to conduct surveillance, restrict the rights of both citizens and noncitizens, and lower the standard of probable cause for warrants. Proponents constitutionally and pragmatically justified this strategy, arguing that the counterterrorism operations conducted fall under the war power authority of the President. As the power of the sovereign executive expanded, three strategies flourished under its protection, invulnerable to democratic constraint.\nTargeted Killing\nA core counterterrorism strategy has utilized aggressive drone warfare. The vast majority of these attacks are \"signature strikes,\" which target \"people whose behavior is assessed to be similar enough to those of terrorists.\"\nHowever, data on these strikes is sparse. Trump reversed a President Obama-era requirement which mandates reporting civilian casualties. The executive's argument...", "pred_label": "__label__POS", "pred_score_pos": 0.8589337468147278} +{"content": "One of the hardest things about the discrepancy between human and canine lifespan is that all dog owners will likely experience the loss of a canine companion during their lifetime. It’s an inevitable reality of having these wonderful dogs in our lives, and it is heartbreaking every single time.\nAt the Dog Aging Project, we often focus on and celebrate the joy our dogs share with us, but we also stand with you through the experience of loss and the journey toward healing.\nIf you want to connect with others, all Dog Aging Project Pack members can join the Dog Park, our online community, at any time. There is a discussion forum dedicated to the topic of loss and grief with others who are also bereaved.", "pred_label": "__label__POS", "pred_score_pos": 0.9590204954147339} +{"content": "Taxes create a considerable amount of stress, regardless of whether your tax situation proves simple or complex. Oftentimes, simply having to set aside time for preparing taxes can prove a hassle. Sometimes, hiring a tax professional to handle your tax return preparation makes sense.\nHowever, if you hold down a traditional desk job and receive a Form W-2 with no other complicating circumstances, preparing the return does not seem hard. Instead, the process seems, well, taxing. Preparing your own return requires carving out time to sit down, review your income and deductible expenses, answer a series of prompts in tax software, review for accuracy, and send it all off to the IRS. In sum, not necessarily a time-intensive endeavor, yet just something else to handle.\nNow, imagine an entirely different scenario: managing a collection of 1099s and a W-2 received in the mail from multiple companies, investing accounts, passive income streams, or other income sources, and then keeping track of the laundry list of tax deductions related to your business or freelancing. Without a doubt, this can sound daunting.\nEven if you have been around the block with this exercise before and feel up to the task, you might still wonder whether you need a tax professional’s help. Despite your level of comfort and familiarity, you might not know everything needed to leverage all applicable tax credits, deductions, or exclusions. Further, you wish to avoid making any mistakes if you decide to prepare your own taxes.\nWhen you face the choice of using tax software or hiring a tax professional, it often comes down to how comfortable you feel preparing your own taxes. After all, if the tax software proves worth its salt, it will do a great job of guiding you through the tax return preparation process.\nIn theory, this should eliminate the need for seeking out the guidance of a tax professional. However, despite the many powerful tax software programs found on the market (e.g., TurboTax, H&R Block, TaxSlayer, to name a few) just because you start down this path does not mean you will not need extra assistance. In that instance, having access to professionals becomes very worthwhile.\nShould you wish to learn more about the best tax software in 2021, have a review of the table below and identify which software best fits your needs. Further, some of these companies also offer quick access to your refund through refund advance products.\n1. If You Earned Income from a Side Hustle, Freelancing Gig or Operating a Business\nAs many of you reading this may have found out last year during tax season, significant changes came to the tax code under the Tax Cuts and Jobs Act. In particular, those who chose to participate in freelancing jobs, side hustle opportunities, or operating their own business.\nFor those entrepreneurial enough to earn extra income (and have it result from a trade or business), they will almost surely qualify for a 20 percent Qualified Business Income (QBI) deduction. However, this QBI tax item represents a complicated new tax rule. To make sense of it fully (and maximize your tax savings), you might consider soliciting the services of a tax professional.\nAs a note, if you operate any of these activities as a sole proprietor, you might also qualify for numerous other benefits. By not having the insight or expertise to navigate this business tax landscape, you might miss out simply by doing your own taxes. And when you have incurred your business startup costs (those are deductible to certain limits!) and these activities scale enough, this could amount to significant tax liability- and potential missed deductions and credits.\nAnd while hiring a professional might seem overdone for only choosing to pursue a minor freelancing opportunity or side hustle, it could still be a good idea for directional guidance. Many deductions exist for businesses and may go unclaimed if not accounted for properly on a tax return. As with most things, sometimes having person-to-person interaction can make a situation run much smoother. Because, while software can serve as a great tool for uncomplicated tax situations, a CPA can really help find tax deductions and credits for you by learning more about your unique circumstances.\n2. If You Have a Significant Portfolio of Investments\nInvestments held in perpetuity often require little maintenance beyond accounting for any dividends or capital gains distributions. However, taxpayers with significant investment portfolios of both traditional investments and alternative investments can still benefit from seeing a tax expert.\nThe reason for this comes when not necessarily considering the purchase or sale of investments reported on a return, but with respect to the tax planning which occurs throughout the year.\nImagine planning your taxes in advance and harnessing immensely more maneuverability when it comes time to prepare your return. For those of you who have enough invested with stock trading apps could benefit by working with a CPA who operates proactively throughout the year. That way, you receive the most benefit come tax time.\nFurther, investing apps for minors can result in tax liabilities to you if your account made trades in a taxable custodial account. If your teenager is starting to invest, handling this might be a challenge and the help of a tax professional could make your life easier.\n3. If You Own and Rent Property\nRental properties act as a great tool for building wealth because they can produce capital gains from appreciation and income from tenants. The numerous deductions, (e.g., MACRS depreciation, landlord insurance, marketing expenses, etc.) associated with the property can shield that rental income from Uncle Sam. By seeking the help of a tax professional, you would better manage the expenses related to maintaining this property.\nAnd should the time come when you decide to sell this rental property, hiring a tax professional to assist with efficiently handling the tax implications of selling might prove profitable. If planned for appropriately, a competent tax professional can avoid the risk of misstating your gains and costing you a significant amount of money in unnecessary taxes. This leads us to the next situation where hiring a tax professional makes sense.\n4. If You’ve Flipped A Fixer-Upper Property (for a Profit)\nClosely related (and a natural conclusion) to the previous instance of when you should consider hiring a tax professional, if you purchased a piece of real estate and and now desire to flip it, you will want to make sure you get these details right. When assessing the tax implications of this transaction, it might appear straightforward on the surface. “We paid $x, invested $y and sold it for $z.”\nIn reality, the number of transactions tied up in this financial decision create a need for close attention to detail. Depending on the money spent, the funds used could either qualify for immediate expensing or as a capital cost accounted for using short-term or long-term capital gains. This distinction hinges on how long you have owned the property and when you invested the money. In truth, knowing how to classify these multiple transactions can feel overwhelming. Handing this difficulty over to a tax professional might prove beneficial to ensure you make the maximum return possible on this investment.\n5. If You And/Or Your Spouse Have Student Loans\nIn few circumstances does it make sense to file separately as married taxpayers because this usually results in a greater tax liability. When you choose to file jointly as a married couple, you often enjoy more generous tax deductions, credits, and options. And you certainly receive more favorable tax brackets as compared to single filers.\nHowever, even though it might not always serve as the best tax solution, some narrow instances exist where filing separately makes sense. In particular, one of the most oft-cited reasons deals with student loans.\nFor those taxpayers who financed their education with federal student loans and therefore have eligibility for participating in an income-based repayment plan like those used by the Public Service Loan Forgiveness program. These plans base your monthly payment amount on your annual income, and, under some circumstances, your unpaid student loan balance could qualify for forgiveness after a certain number of years.\nAs a result, filing separately could artificially lower your income in the eyes of loan forgiveness programs. Before proceeding down the path of filing separately, however, sit down with a CPA or tax professional to identify the tax impact.\nAdditionally, accounting for student loan interest often costs extra with most online tax software programs. Adding this to a list of discussion items with a CPA might prove beneficial, especially if you qualify for the student loan interest deduction, which may have decreased after you refinanced your student loans.\nHowever, tax pros might be overkill for handling this tax deduction because the most popular online tax software programs offer packages which allow claiming the student loan interest deduction a breeze. Have a look at the following table and then click through to each software program’s review to see which package works to capture this need and the others cited on this list.\n(1) Prices subject to change; prices listed represent full-retail cost.\n(2) Discounted prices shown at time of review were $29.95, and $39.95, respectively. 6. If You Have Experienced A Life Change, Such As A Move Or Divorce\nLife has many turns, whether that includes moving cross-country, a change in family status from tying the knot (or breaking it), or welcoming a new child to the family. Because of any of these events, you want to prepare accordingly from a tax perspective.\nUndoubtedly, the number of events affecting your filing status and claims never end. As a result, navigating these changes might not always seem so straightforward. Choosing to outsource this decision-making to a professional could make any tax benefits work to your advantage. Further, this could also utilize other tax strategies to minimize your tax liability.\nAs discussed above, marrying comes with more tax benefits (as compared to filing as a single taxpayer). Regarding divorce, changes occurred under tax reform affecting the deductibility of alimony paid. New rules allow a person making qualified alimony payments to deduct them against taxable income while alimony payments received by the former spouse become taxable and therefore must figure into the recipient’s income.\nOn the other hand, the taxpayer providing child support cannot deduct it while the payments transfer tax-free to the recipient.\n7. If You Had Tax Issues In The Past\nSometimes the best choice involves not making the same mistake twice. In years past, if you the IRS chose to audit your tax return for accuracy, you have a higher likelihood of receiving another scrutinizing eye from Uncle Sam.\nIf you have found yourself in such a situation, whether audited or the recipient of a notice, having a tax professional in your corner might prove useful. Many online tax software services have begun offering services related to audit defense for such instances.\nFinally, if you have received such a notification from the IRS, speaking with a tax professional should help you to understand your situation and how best to proceed, including necessary tax forms and documents, statements of fact, and substantive evidence or any positions taken.\n8. If You Adopted A Child\nUnderstanding the importance of welcoming a new child into a stable environment, both the IRS and many states offer favorable tax items for adopting a child. Because this represents a major decision, you may wish to consider consulting a tax professional beforehand to ensure you have taken advantage of the adoption tax credit properly.\nTake special note that in circumstances when a taxpayer claims a tax credit like the adoption tax credit or earned income tax credit which triggers a refund, the IRS wants to keep close tabs on this election. When a tax election results in a cash outlay from Uncle Sam, the scrutiny from the IRS will increase, thus posing a significantly higher audit risk, all things equal.\n9. If You Make More Than $200,000 Per Year\nStatistically speaking, the IRS receives a lot of money from high-income individuals, solidifying the age-old phrase: “More money, more problems.” As with most things in the world of high-incomes, you become a target: for marketers or Uncle Sam alike. You have deep pockets and they want a cut.\nHigh income earners represent an opportunity to get more bang for the government’s buck with an audit because more money is at risk. Applying the 80/20 rule would necessitate the IRS spend a great deal of time meticulously reviewing these returns since 20% of the population would pay 80% of the taxes. While surely an approximation, the concept remains valid: follow the money because any mistakes at this level result in more missed opportunity on the part of Uncle Sam.\nFurther, high income earners understand the value of hiring a tax professional because they can claim many lucrative tax breaks. However, in claiming such positions, the IRS will demand justification of potentially aggressive tax decisions.\nAll things equal, you can expect as your income rises, so too does the scrutiny from the IRS to make sure they will not be short changed on their tax payments.\n10. If You Have Sold Stock Via Stock Options Through Your Employer\nIn circumstances where you sold stock through stock options with your employer, it could very easily be a circumstance where the cost basis reported on your Form 1099 has been calculated inaccurately. As a result, you may also not have withheld a sufficient amount of money on the transaction and you face significant tax liability.\nFurther, because the cost basis might be inaccurate, you may need to make special adjustments to avoid double taxation.\n11. If You Installed a Solar Energy System\nSolar energy continues to grow in popularity. Many new systems went up this year and so too have the number of taxpayers claiming the solar energy investment tax credit, a lucrative credit meant to refund up to 30% of the solar system’s installed costs.\nBecause what counts as a qualified installed costs matters, seeking the help of a tax professional may result in a low tax liability (this credit is non-refundable, meaning it cannot trigger a tax refund).\n12. If You Have Any Foreign Assets\nDon’t like dealing with taxes in the United States? I cannot imagine adding complexity from dealing with taxes in a foreign country make matters any less stressful. However, if you hold foreign assets (e.g., bank accounts, retirement accounts, foreign-held investments, a condo abroad, etc.), you want to consult a tax professional to determine what you should report to the IRS.\nIn recent years, the government has developed a heightened interest in such assets as they examine taxpayer decisions to offshore their assets and evade taxation. And for those who get caught? You can expect steep penalties.\n13. If You Received Life Insurance Proceeds as a Beneficiary\nIn most cases, life insurance proceeds are not taxable. However, certain circumstances apply where that might not be the case. Make sure the term life insurance purchased is worth it and then whether it qualifies for exemption from reporting it on your tax return.\nRelated:\nWhat is Imputed Income for Life Insurance What is the Cash Surrender Value of a Life Insurance Policy? What is an Insurance Declaration Page? All About the DEC Page What are Insurance Riders and Endorsements? What You Need to Know 14. If You Worked In Multiple States\nSimilar to moving across state lines, you might have worked a job, owned a business, or freelanced in multiple states throughout the year. The reasons for these varied work geographies can result from a move, your work relocating you either temporarily or permanently, or perhaps even from maintaining a regular travel schedule that keeps you working on the road. Regardless of rationale, working in multiple states for extended periods of time can still result in tax liability in those different states.\nCommonly, professional athletes must file multiple state-level returns, because even though they may have played only a handful of games in a particular state, 3 days / 365 days per year * * 5% (assumed effective state tax rate) * $20,000,000 salary = $8,219 in state income tax paid.\nWhile not likely a professional athlete, you may still have worked in different states and face tax liability in each. As a result, your circumstances can quickly result in a complicated return preparation. Depending on the level of effort, you might consider passing the hassle off to a tax professional.\n15. If You Want To Save Time\nLife offers many joys and often not enough time to enjoy them. Why let tax prep act as one of those deterrents? What little time you do have for pursuing interests should not go wasted doing something you do not enjoy. In all likelihood, you would rather spend time with friends and family or doing something you enjoy. In other words, not preparing a tax return.\nAs a result, hiring a tax professional may make for a better use of your time and money. The tax pro should handle your taxes adequately and minimize your tax liability within the confines of law. For your part, you likely only need to upload necessary tax documentation and the tax pro handles the rest.\n16. If You Want Peace Of Mind\nPeace of mind should act as a primary driver for preparing your tax return. If reviewing tax code interpretations, deciphering Section 1231 from 1245 and 1250 property gains, or understanding the new limits to the Section 179 deduction does not sound like fun, you might consider hiring a tax pro. Alternatively, you could dramatically simplify your life and remove all this complexity to avoid preparing a complicated return! Admittedly, that sounds a lot more like the tail wagging the dog.\nVisiting a tax professional may also provide opportunity to extract any missed credits or deductions you neglected to claim in the past. As a point of fact, the IRS allows you to amend tax returns for the previous three years and claim missed refunds on account of mistakes. Should you face this situation, hiring the tax pro might actually prove profitable and provide peace of mind. Surely, a combination everyone strives for during this time of year.\nTax Software to the Rescue\nIf none of the above situations apply, do not resonate with you, or you still wish to go it alone, numerous online tax software programs are available. Consider any of the following options and read reviews for each one to see which package makes the most sense for your circumstances.\nIf you have a simple tax situation, you likely do not need to pay up for the bells and whistles of TurboTax or H&R Block, unless you may also like access to a tax professional. After all, you may not want to go to the tax professional dance, but you’d still like an invite.\nAlertMe\nImage Credit: DepositPhotos.com", "pred_label": "__label__POS", "pred_score_pos": 0.6658612489700317} +{"content": "Many hotels, restaurants, and similar institutions operate or contract for a valet service. This service is essential for smooth entrance to and exit from your business, and can be vital in reducing the pressure of traffic congestion on your front doors.\nNaturally, valet parking contains risks, which can be amplified under tight driving conditions, or other pressures relevant to the job. Carrying comprehensive valet insurance will ensure you are protected for any valet parking liability that may arise in the course of business.\nWhat Risks Exist When Using Valet Parking?\nDriving always contains inherent risks, but certain hazards can be amplified by valet parkers. The necessity to work on a tight schedule, and often in cramped conditions, can create specific hazards — as can the need to operate widely varying vehicles.\nEnsuring your valet staff is well-trained and competent with vehicles of varying type and size will reduce the risk of an accident. Additionally, hiring only employees with clear driving records, and sufficient experience, can both be immeasurably helpful.\nA reputable insurer can help you take these steps to streamline the safety of your operation. Moreover, they can help design a suite of valet parking liability insurance that ensures that you are well-protected, in the event an accident or any damage does occur.", "pred_label": "__label__POS", "pred_score_pos": 0.9801962971687317} +{"content": "Aim: Vancomycin (VCM) is a glycopeptide antibiotic widely used to treat serious infections caused by methi-cillin-resistant Staphylococcus aureus and has been associated with some severe side effects such as hepatotoxicity and nephrotoxicity. However, the underlying mechanism of VCM-induced hepatotoxicity is not yet fully understood. Therefore, the current study was designed to evaluate the protective effects of zingerone (Zin) against VCM-induced hepatotoxicity in rats.", "pred_label": "__label__POS", "pred_score_pos": 0.9991902112960815} +{"content": "Sea kale is also called sea-colewort, scurvy grass, and halmyrides. It is a hardy perennial whose shoots are similar to asparagus in the way they grow from the roots. However, the leafy top does not resemble asparagus. The plant grows to 2 feet, with large, heavy, glossy green leaves that are fringed or curled on the edges. The edible, young, tender, whitened shoots arise from the roots each spring in areas where it is adapted. Like asparagus, sea kale is not well adapted to Florida, for it requires a cool, moist climate. It grows wild abundantly on the West European seaboard, especially in the British Isles.\nCulture\nTo produce the crop, seeds or cuttings are planted in beds where the roots are maintained for several years. As the young shoots emerge from the roots upon resumption of favorable growing conditions each spring, they are blanched (whitened) by heaping soil upon them or by covering with a suitable device such as a pot to exclude light. Young shoots are harvested when 4–5 inches long, crisp, and tender before leaves start to expand.\nDo not confuse sea kale with sea-kale cabbage, an altogether different vegetable.\nUse\nIts name comes from its use on long sea voyages. The Romans stored it in pickled form aboard ship and fed it to the crews to prevent scurvy. In fresh form, it is cooked and used like asparagus. Both the young shoots and very small leaves are eaten.", "pred_label": "__label__POS", "pred_score_pos": 0.9007216691970825} +{"content": "On 25 April, 2015, a 7.8 magnitude earthquake struck Nepal. This has been the worst disaster in Nepal’s recent history resulting in loss of nearly 9,000 lives. Heifer invested $ 4.15 million to support 54,547 families in 13 districts to rebuild their livelihoods and communities.\nFollowing torrential rain in early August of 2014, Nepal suffered flood and landslides in the Tarai region. A total of 25 districts were inundated by the flood. According to the Home Ministry, almost 300 people lost their lives while thousands of families were displaced.\nYear 2020 was challenging for Heifer due to the COVID-19 Pandemic and its repercussions but what was more severe was the crisis that loomed in livelihoods of majority of the smallholder farmers, project holders, partners and the marginalized communities that we are working with.", "pred_label": "__label__POS", "pred_score_pos": 0.8771116733551025} +{"content": "This study involved examining how splitting a 30-min exercise bout on a cycle ergometer into two equal sessions affects excess postexercise oxygen consumption (EPOC) and resting metabolic rate (RMR). In this study, 10 male volunteers (age = 23+/-3.8) participated in two exercise trials, which were randomly assigned in a counterbalanced design and separated by 40 hr. One trial was 30 min of exercise at 70% VO(2)max (CONT), followed by a 40-min measurement of EPOC. The second trial was divided into two 15-min sessions (SPLIT), separated by 6 hr. A 20-min measurement of EPOC followed each SPLIT session. Results indicated that the combined magnitude of EPOCs from SPLIT (7,410+/-1,851 ml) was significantly greater than that from CONT (5,278+/-1305 ml). Data indicate that dividing a 30-min exercise session in to two parts for these individuals significantly increases magnitude of EPOC but does not affect RMR.", "pred_label": "__label__POS", "pred_score_pos": 0.9999510645866394} +{"content": "Abstract\nBlockchain is well known as a decentralized and distributed public digital ledger, and is currently used by most cryptocurrencies to record transactions. One of the fundamental differences between blockchain and traditional distributed systems is that blockchain's decentralization relies on consensus protocols, such as proof of work (PoW). However, computation systems, such as application specific integrated circuit (ASIC) machines, have recently emerged that are specifically designed for PoW computation and may compromise a decentralized system within a short amount of time. These computationally resourceful miners challenge the very nature of blockchain, with potentially serious consequences. Therefore, in this paper, we propose a general and flexible PoW method that enforces memory usage. Specifically, the proposed method blocks computationally resourceful miners and retains the previous design logic without requiring one to replace the original hash function. We also propose the notion of a memory intensive function (MIF) with a memory usage parameter k (kMIF). Our scheme comprises three algorithms that construct a kMIF Hash by invoking any available hash function which is not kMIF to protect against ASICs, and then thwarts the pre-computation of hash results over a nonce. We then design experiments to evaluate memory changes in these three algorithms, and the findings demonstrate that enforcing memory usage in a blockchain can be an effective defense against computationally resourceful miners.\nKeywords ASICs Blockchain Hash Pow", "pred_label": "__label__POS", "pred_score_pos": 0.9923075437545776} +{"content": "Abstract\nTriclosan (TCS), an extensively used antimicrobial agent, has raised considerable concern due to its hepatocarcinogenic potential. However, previous hepatotoxicity studies primarily focused on the activation of specific intracellular receptors, the underlying mechanisms still warrant further investigation at the metabolic level. Herein, we applied metabolomics in combination with lipidomics to unveil TCS-related metabolic responses in human normal and cancerous hepatocytes. Endogenous and exogenous metabolites were analyzed for the identification of metabolic biomarkers and biotransformation products. In L02 normal cells, TCS exposure induced the up-regulation of purine metabolism and amino acid metabolism, caused lipid accumulation, and disturbed energy metabolism. These metabolic disorders in turn enhanced the overproduction of reactive oxygen species (ROS), leading to the alteration of antioxidant enzyme activities, down-regulation of endogenous antioxidants, and peroxidation of lipids. TCS-induced oxidative stress is thus considered to be one crucial factor for hepatotoxicity. However, in HepG2 cancer cells, TCS underwent fast detoxification through phase II metabolism, accompanied by the enhancement of energy metabolism and elevation of antioxidant defense system, which contributed to the potential effects of TCS on human hepatocellular carcinoma development. These different responses of metabolism between normal and cancerous hepatocytes provide novel and robust perspectives for revealing the mechanisms of TCS-triggered hepatotoxicity.\nScopus Subject Areas Chemistry(all) Environmental Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.9934433102607727} +{"content": "Representation, COVID-19, and failed metaphor: A critical analysis of the Bay of Plenty District Health Board vaccine booklet Abstract\nThis paper will critically analyse the Bay of Plenty District Health Board’s (BOPDHB) controversial vaccine booklet, which featured mataora-adorned cartoon images of the COVID-19 virus. This imagery caused a furore with anecdotal evidence from social media suggesting that Māori were outraged by the portrayal of Māori in this way.\nThis paper will offer two arguments. The first argument builds on Hokowhitu’s (2001) work, which deconstructed representations of Māori as animalistic, savage-barbarian, physical-unintelligent, mythical, bewildered-childlike, and romanticised-noble. The first argument will extend Hokowhitu’s (2001) analysis by deconstructing the representation of Māori as disease-virus. While it is impossible to understand the BOPDHB’s intentions, the second argument posits that the objective might have been to use the concept of taniwha as a metaphor for COVID-19. Though this argument is significantly weaker than the first, it still warrants some exploration, even if only to provide a sense of balance to this paper.\nTe Kaharoa, 17(1). https://doi.org/10.24135/tekaharoa.v17i1.363\nThis work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.", "pred_label": "__label__POS", "pred_score_pos": 0.9863335490226746} +{"content": "Kids with sensory processing issues encounter an excess of or too little stimulus through these faculties. They may likewise experience issues coordinating sensory data. Additional Signs 11. They may have difficulty making transitions from situation to situation. 12. Lack self-control. 13. Delays in speech or language. 14. Problems with academic achievement. 15. They may crave organization in everything they do from their room to the food on their plate. 16. Have trouble with hand-eye-foot coordination. 17. Bites Toys and sometimes people 18. May perform risky behavior during plays 19. Deliberately crashes on objects 20. Hold pencil and paper too tightly 21. Difficulty looking at listening at the same time 22. Gags easily, difficulty swallowing 23. Does not express emotion\nOnce you figure out that piece of the puzzle, you can then start working on a cure. Parents go through a whole spectrum of emotions upon learning about their children, such as grief, denial, or anger. However, this is a crucial turning point in the development of both parents. They are now presented with the opportunity to turn this adversity into a lifelong journey.\nConverse with your kid about how they can manage their conduct. Assist them to distinguish their triggers and the physical reactions. You may, in fact, have to go through a process where you determine the best treatment plan for your child’s sensory issues. The point is that you as the parent know your child better than anyone, so you are the best judge of his or her character. Remember, consistency is key. Once you have your child in the correct area make sure you use positive praise and reinforcement. Provide your child with reassurance for staying in their area.", "pred_label": "__label__POS", "pred_score_pos": 0.7739658951759338} +{"content": "Humans are increasingly interacting with machines through language, sometimes in contexts where the user may not know they are talking to a machine (like over the phone or a text chatbot). We aim to understand how system designers and researchers might allow their systems to confirm its non-human identity. We collect over 2,500 phrasings related to the intent of ``Are you a robot?\". This is paired with over 2,500 adversarially selected utterances where only confirming the system is non-human would be insufficient or disfluent. We compare classifiers to recognize the intent and discuss the precision/recall and model complexity tradeoffs. Such classifiers could be integrated into dialog systems to avoid undesired deception. We then explore how both a generative research model (Blender) as well as two deployed systems (Amazon Alexa, Google Assistant) handle this intent, finding that systems often fail to confirm their non-human identity. Finally, we try to understand what a good response to the intent would be, and conduct a user study to compare the important aspects when responding to this intent.", "pred_label": "__label__POS", "pred_score_pos": 0.9947460889816284} +{"content": "Your rooftop is a focal component of your home’s construction and offers your family and having a place assurance against severe climate. Cleaning, fixing, or supplanting assists with guaranteeing that your interest in your house is protected, and ordinary rooftop upkeep is significant. Rooftop cleaning is a cycle through which form, green and dark green […]", "pred_label": "__label__POS", "pred_score_pos": 0.5689617395401001} +{"content": "The no-collateral feature of a personal loan makes it one of the most sought-after forms of a loan; because it can be used to meet any immediate financial needs, be it, wedding, home renovation, or travel. While applying for one is easy, getting approval on the loan application process could be daunting because it depends on several factors.\nLet’s check out some reasons for the rejection of a personal loan application: Poor Credit Score: To evaluate a customer’s creditworthiness, banks perform a check on CIBIL scores. Maintaining a credit score of 700 and above helps you get approval. Avoid overusing your credit card and making erratic loan payments. Pay off outstanding dues. However, StashFin offers personal loans even with a low credit score; you can repay on schedule and improve your credit score. Multiple Loan Enquiries: Lodging multiple inquiries within a short period can lead to your loan application being rejected. Because you may be perceived as someone who is credit hungry or someone who is always dependent on borrowed money. This can affect your credit score negatively. So, before applying for a loan ensure to conduct proper research and compare your options in advance. Existing Debts: If you have too many credit cards debts and outstanding loans, it’s best to clear them all before applying for a personal loan. Because the lender may perceive you as someone overburdened with credit, which may result in your loan application being rejected. With StashFin, you can apply for debt consolidation personal loans to clear all your debts, and further you can reprice the loan amount with a good repayment history. Eligibility Criteria: Sometimes your annual income might not match the minimum income requirement defined by the lender, this might result in the rejection of the loan application. At StashFin, you can avail a personal loan with a minimum salary of Rs. 18,000 per month. This can be done by submitting minimum documents like salary slips and bank statements through their quick online form. Unstable Employment: Financial institutions prefer businesses with consistent income and individuals with stable employment. Quitting or switching between jobs frequently will not only result in loan applications being rejected, but lenders might even end up charging higher interest rates.", "pred_label": "__label__POS", "pred_score_pos": 0.8059425950050354} +{"content": "“Pubs play a vital role in many local communities, offering a hub where people can come together for a range of activities and life milestones. Even when there isn’t a poignant event on the horizon, pubs act as a local support network and help combat loneliness and isolation. Every pub that closes sees a licensee or manager’s livelihood lost, along with that pub’s staff. Their importance in many individual’s lives cannot be overstated.\n“Instead of closing a thousand pubs, we need greater support for them through a fairer business rates package and a stronger Pubs Code, to make sure all pubs are viable.”", "pred_label": "__label__POS", "pred_score_pos": 0.5624580979347229} +{"content": "While Western markets struggle to recover from the global financial crisis, Asian economies are growing rapidly. APAC consumers are therefore becoming richer, better informed and more widely traveled. This is leading to greater competition for their business- in order to succeed, companies need to enhance customer loyalty.\ngap\nPublished on: June 04, 2015", "pred_label": "__label__POS", "pred_score_pos": 0.6112217903137207} +{"content": "We analyzed brain MRI data from 372 young adult twins to identify cortical regions in which gray matter thickness and volume are influenced by genetics. This was achieved using an A/C/E structural equation model that divides the variance of these traits, at each point on the cortex, into additive genetic (A), shared (C), and unique environmental (E) components. A strong genetic influence was found in frontal and parietal regions. In addition, we correlated cortical thickness with full-scale intelligence quotient for comparison with the A/C/E maps, and several regions where cortical structure was correlated with intelligence quotient are under genetic control. These cortical measures may be useful phenotypes to narrow the search for quantitative trait loci influencing brain structure.", "pred_label": "__label__POS", "pred_score_pos": 0.9023036956787109} +{"content": "A shifting public policy landscape has placed transgender youth at the center of state-level efforts to prohibit access to gender-affirming care and participation in athletics. Join us for a discussion on how public policy debates are shaping state-level environments for transgender people. The webinar will also present new estimates of the population of transgender adults and youth in the U.S.", "pred_label": "__label__POS", "pred_score_pos": 0.8822290897369385} +{"content": "A recent study has revealed that most women prefer men with potbellies to men with six-packs outlining the main reason behind this phenomenon.\nMany people assume that women date men with potbellies or simply chubby men just because of money but this is not true. Although a section of ladies admits to date them for financial support, research has revealed the real secret behind it.\nIn a study that was conducted by Erciyes University in Turkey, it was found that men with potbellies have strong stamina between the blanket as compared to those men with six-packs. Besides, the study further indicated that men with potbellies have a hormone called oestradiol, which is a s3x hormone that delays their orgas-m.\nThe study focussed on 200 men comparing their body mass index (BMI) and their ability to perform in bed. The study found that those with bigger bellies and higher BMI lasted at least 7.3 minutes in bed on average as compared to those fit men (the six-pack) who lasts at around 2 minutes with the majority suffering from premature ejacula-tion", "pred_label": "__label__POS", "pred_score_pos": 0.9099527597427368} +{"content": "The Georgia Historical Society, headquartered in Savannah, Georgia, is the oldest cultural institution in the state and one of the oldest historical organizations in the United States. It is the only statewide historical society in Georgia. Since 1839, the society has collected, examined, and taught Georgia history through a variety of educational outreach programs, publications, and research services.\nA historical society is a organization dedicated to preserving, collecting, researching, and interpreting historical information or items. Originally, these societies were created as a way to help future generations understand their heritage.\nHistorical societies vary in specialization, with focuses ranging from specific geographical areas such as countries or towns, universities, railways, ethnic and religious groups, to genealogy, pioneer history, and the preservation of antiques or historic buildings.\nOften, many of these organizations ensure that historic architecture is preserved/restored and period houses are maintained for tours open to the public. (See: Historic preservation)\nHistory\nIt is said that historical societies originated in Western Europe during the 16th and 17th centuries. These early organizations were usually formed as societies for “lovers of Antiquity.”\nThe oldest historical society in the United Sates is what we now call the Massachusetts Historical Society, which was founded in 1791 by Jeremy Belknap. He was joined by nine other Bostonians who helped him create \"The Historical Society,\" an organization truly devoted to collecting materials for the study of American history. This like-minded group gathered family papers, books, and artifacts from their personal collections which led to the creation of the nation's first historical repository. Due to the absence of any other American historical repositories during this time, the MHS took on a national role - Something that is still evident in its collections and publications. To this day, Belknap's original vision of preserving, collecting, making resources accessible, and communicating manuscripts that promote the study of Massachusetts as well as the nation is still thriving.\nA society is a group of people involved in persistent social interaction, or a large social grouping sharing the same geographical or social territory, typically subject to the same political authority and dominant cultural expectations. Societies are characterized by patterns of relationships (social relations) between individuals who share a distinctive culture and institutions; a given society may be described as the sum total of such relationships among its constituent members. In the social sciences, a larger society often evinces stratification or dominance patterns in subgroups.\nInsofar as it is collaborative, a society can enable its members to benefit in ways that would not otherwise be possible on an individual basis; both individual and social (common) benefits can thus be distinguished, or in many cases found to overlap.\nA society can also consist of like-minded people governed by their own norms and values within a dominant, larger society. This is sometimes referred to as a subculture, a term used extensively within criminology.\nThe play originally ran at the Prince of Wales's Theatre, Liverpool, under the management of Mr A. Henderson, opening on 8 May 1865. It was recommended to Effie Wilton, the manager of the Prince of Wales's Theatre in London's West End, by H. J. Byron, where it ran from 11 November 1865 to 4 May 1866 Robertson found fame with his new comedy, which included a scene that fictionalized the Fun gang, who frequented the Arundel Club, the Savage Club, and especially Evans's café, where they had a table in competition with the Punch 'Round table'. The play marked the London debut of Squire Bancroft, who went on to marry Effie Wilton in 1867 and become her co-manager.", "pred_label": "__label__POS", "pred_score_pos": 0.5236034989356995} +{"content": "Define cost.\nSolution 1\nCosts are the total of expenditure incurred by the producer in producing a good. It includes the cost of factor inputs and non-factor inputs of the production of a good.\nSolution 2\nCost of production is the expenditure incurred by a firm on the factor inputs such as land, labour, capital and entrepreneur and non-factor inputs such as raw materials for the production of a good.", "pred_label": "__label__POS", "pred_score_pos": 0.9799878001213074} +{"content": "FLERSPRÅKIGHET I EUROPA - En diskursanalys av centrala EU-dokument om språklig mångfald\nSammanfattning: This thesis aims to study the European Commission's documents written aboutmultilingualism in Europe. A discourse analysis is used to explore how language used by theCommission displays their construction of arguments and the use of language ideologiesamongst other things.The results present us with three types of topoi otherwise known as argumentative patterns:(1) An economical topos with an abundance of references to the common market. (2) Acultural topos exhibiting the cultural values of the EU, and lastly (3) a european identity toposconstructed to create a connection between citizens and the institutions.In conclusion we can see how these topoi connect to one another through the spillover effectthus making the discourse of multilingualism centered amongst other measures of integration.The absence of discussion within the material is also a focal point as the Commission’sposition in power enables them to construct the discourse towards their advantage.\nHÄR KAN DU HÄMTA UPPSATSEN I FULLTEXT. (följ länken till nästa sida)", "pred_label": "__label__POS", "pred_score_pos": 0.7771176099777222} +{"content": "Family resilience: understanding, fields of application, contributions and challenges\nWe conducted a literature review to establish the state of the art and conceptualisation of family resilience between 2010 and 2016. Even if still incipient, there is an increase in both empirical and theoretical-reflective research, which involves a higher relevance in terms of research and interve...\nAutor Principal: Formato: Artículo (Article) Lenguaje: Español (Spanish) Publicado: Universidad Santo Tomás, Colombia 2018 Materias:", "pred_label": "__label__POS", "pred_score_pos": 0.8627480268478394} +{"content": "A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.The file type is\napplication/pdf.\nThe teacher-student (T-S) matching in colleges has not been studied in a thorough and systematic manner. It remains unclear how college T-S matching affects the knowledge innovation of graduate students. Therefore, this paper firstly analyzes the factors affecting the knowledge innovation of graduate students, and selects the T-S matching mode that promotes their knowledge innovation. Then, the promotion of knowledge innovation was investigated under the T-S matching. Finally, the authorsdoi:10.3991/ijet.v15i20.17421 fatcat:jytucrvccjbjngrotm4wx73vsy", "pred_label": "__label__POS", "pred_score_pos": 0.6876908540725708} +{"content": "A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.The file type is\napplication/pdf.\n2021 Energies\nThe constant increase in electrical energy consumption has led to a growth of photovoltaic installations (PV) along with the corresponding power converters for proper operation. Power electronics converters represent a challenge to maintain the system's performance and safety; one such problem is series DC Arc Fault (AF). DC AFs lead to fire risk, damaging the main bus and the loads when not detected and interrupted in time. Therefore, research about DC AFs in power electronics converters mustdoi:10.3390/en14113005 fatcat:wzxb544u65bbffyf7itchvgocq", "pred_label": "__label__POS", "pred_score_pos": 0.8008334636688232} +{"content": "FCA product value findings\n06 September 2021\nThe UK Financial Conduct Authority (FCA) recently published its findings following a review regarding product value and coronavirus. While the review focussed on the general insurance sector, the FCA’s findings will be relevant to other firms as they relate to certain FCA priority items such as the new consumer duty, governance, ensuring good customer outcomes and reducing consumer harms. Below we provide some practical considerations for firms on some of the key points and how these elements can apply across a wider range of products and services.", "pred_label": "__label__POS", "pred_score_pos": 0.9997324347496033} +{"content": "cognition & appointment\nUpdated: Aug 17\n\"When in doubt, simplify. Perhaps the goal can be better understood as a moment of silence. It doesn’t sound as fancy as 'enlightenment,' but even one moment of true silence can have a profound impact. When you are truly silent, there are no obstacles between you and the truth. In the space of that moment, what you seek can reveal itself. Just be careful not to attach to that idea either, for the moment you realize you have reached that moment is the moment that you have fallen out of it.\"\n- Miguel Chen,\nhttps://www.lionsroar.com/not-enlightened-yet/\nA tool for when the mind feels spinny, a map for inner reorientation at heart center.\nWe thrive when attention is situated in the here & now. As attention gets pulled / goes chasing, presence diminishes, compromising response-ability. Our body's there but our mind isn't. That disconnect spawns stress, disorientation, confusion, hostility, and the various other roots of suffering.\nTwo common lures are association & curiosity.\nAssociation tends to pull us into an imagined past. We see x and are reminded of y, e.g. we see an apple & think of that time, what was it, 6ish year so, or was it 7, we went apple-picking. Body is in the present, mind is drifting toward the remembered - really, reimagined - past. Then another lure flashes, the invitation to compare - was I happier then or now? Would I rather be here or there? What about my current moment is like apple-picking?\nNow the mind's beginning to spin: it's simultaneously trying to track the original association, the new comparison, and the body-present. If it's really spinny, it may start threading new associations & comparisons into the mix, creating a cereberal cat's cradle of thought streams. At this point, disorientation sets in, it may feel like a tail spin, and so we instinctively grasp - onto the same spinning momentum we started, with an \"any port in a storm\" mentality. We've now turned the spin into our stability, similar to the way a space ship can use rotating to simulate gravity.\nThis is where we're most confused. We've achieved artificial stability through spinning, which generates more association-comparison loops, which generates more spinning, more grasping, more... In the midst of this perpetual dis/re-orientation, our body-present is like the earth seen from the spaceship - you're aware of it, but nowhere close to touching it, to flowing with it, to being it. Reconnection with body-present seems daunting, even impossible. And even if we muster the clarity & courage to try, the perpetual grasping-spinning makes it difficult to stay focused on the effort.\nMental energy can spend hours in these loops. Once looping becomes a habit, our mental energy may stay trapped there continuously, becoming part of who we are. Like in PTSD, there are associations - loud sudden noises, a smell, a certain fabric - which rip mental energy from present awareness, trigger an association with a traumatic past event, spook the disoriented mind into clinging, & the loop becomes more absorbing than the present body moments, until we're more associated with the looping than the flow of time.\nCuriosity works similarly: something prompts us to think, \"I wonder...,\" \"what if...,\" etc. Where association tends to pull us toward a re-imagined past, curiosity tends to pull us toward an imagined future. Mental energy now moves into imagination, which creates an engrossing mental projection of our curiosity's urge. The projection may reveal something tantalizing, something horrifying, something that sparks more curiosity. Drawn to the intensity & seeming importance of the projection - ooo, cupcake; oh no, Freddy Krueger! - we may insist on remaining in the projection, perhaps to milk more pleasure or other feelings from it, or under the impression that we're solving a problem in there. Now the mind is trying to track the original curiosity, the growing insistence, & the increasingly distant body-present. Spinning...grasping...artificial orientation...swelling confidence coupled with metastasizing confusion...and our minds are in another world while the body is in ours.\nBeing so strongly identified with our minds, we, attention-awareness beings, tend to chase mental energy down its rabbit holes, leaving the body to fend for itself in the continuous flow of time. Indicators include increasingly robotic & reflexive behavior, feeling annoyed/disrupted by occurrences in environment, feeling hollow & numb in body, slouching, etc. - the signs of a body with a groggy or dreaming pilot. We might also think of it like a child whose parent is spaced out on the couch & there's increasingly frantic knocking on the door.\nOur saving graces here are appointment & recognition.\nAppointment is recentering awareness in the heart. Feeling the pulse & breathing into the heart space are two physical paths in. Attitudes for appointment include \"ahhh,\" \"so,\" and other mindsets of acceptance & integration. Centering thoughts include \"softness\" & \"stillness.\" We stop trying to figure things out & reconnect with the heart, a pulsing piece of us always immersed in the present, always thumping along with the rhthym of universal space-time - indeed, the heart is a dynamic, feelable portion of space-time itself. Anytime you sense things are off, spinny, etc., practice appointment.\nThere's a lightning-thunder effect here, perhaps driven by intuition-cognition. Intuitively sensing we're out of whack, we appoint in a flash. The thinking mind gradually realizes over the next few moments that something's changed. Once thinking mind (cognition) realizes acting mind (intuition) has reappointed, it can join the effort by encouraging reappointment with heart-space breathing, with recurring reminders to reappoint, with the assertion of will to remain appointed. (This dichotomy of intuition-cognition might mirror Daniel Kahneman's System 1 and System 2.) We've now gone from the vicious spiralling of thinking-clinging into the virtuous cycling of appointment-disappointment-reappointment. This increasingly anchors presence in heart-center, providing an abiding, trustworthy orientation from which to observe, experience, & engage the flow of time.\nRecognition too has a lightning-thunder quality. Interestingly, it works using the same mechanisms that pulled us into the spirals - association & curiosity. In a flash, our mind recognizes it's spiralling. Having seen so many times now where that spiral goes - lugeing a tightening spiral of confusion -, recognition associates the spiralling with suffering. Curious how to stop the spiralling, the mind sifts through the card deck of memory for a solution. If we've trained the mind to reappoint, recognition will now prompt reappointment.\nRecognition also helps us better comprehend the patterns of our spiralling. We may notice we spiral more when tired, that certain tones of voice trigger us, that curiosity about money is difficult to resist even consciously, etc. With repetition, recognition builds a library of data about our spiralling tendencies, providing us valuable intelligence for shortening our time in spiralling & increasing our time in appointment.\nAs we master our spiralling-appointment cycles, we find that new challenges arise, forcing us to refresh & flex our recognition. Suddenly we're making new associations, chasing new curiosities, and our old methods aren't working. Naturally, we're discouraged, having grown comfortable & confident in our hardwon skills.\nThis is a fork in the road. We can quit or recommit.\nIf we quit, saying it's unfair, the goalposts keep moving, the carrot always remains dangling before my nose, or another victimhood story, we remain stuck in our current cognition. We grow lazy, the waters of our thinking grow stagnant, & we stop learning new skills for recognition & appointment. We become like a frog who has left the excitement & uncertainty of the riverbanks for the slowness & predictability of a private swamp. A fine strategy for recharging and refreshing. But beware the Hotel California effect - \"relax, said the night man / we are, programmed to receive...\"\nIf we recommit, refresh our willingness, we continue to grow. Our sphere of awareness will continuously contract & expand, reaching greater expanses with time, gradually reconditioning our minds to increasingly broad & variable states of being. As these states repeatedly expand to the edge of our spiralling and beyond, we gain a new perspective on our addiction patterns, enabing us to gradually soften our attachments to them. Some, like Siddhartha, may reach a state where awareness rests sustainably beyond the curling dynamics of a chasing mind. Here I picture a mind like an eagle, soaring in widening rings, with the body mercifully & joyously liberated from the push-and-pull of the mind's ever-shifing attachments. May we all experience at least a semblance of such profound peace & harmony.\nJedi tricks for appointmnet include (there are roughly 84k): stillness, softenness, attentively letting go, counting breaths, feeling into the heart beat, smiling, winking, coyly sticking out tongue, saluting the spirit of silliness (my silliness talisman is the rooster), refreshing nose breath, \"ahhhhhhh,\" raspberry/blubbery lips, singing/humming, dancing, playful jibberish, attentively begging, splash of cold water, the feeling of sunlight on skin, fond memories consciously engaged, a heartwarming story or joke, anaesthesia videos (a silly showcase of the disinhibited, disoriented mind), a quality rom-com watched with an open heart...", "pred_label": "__label__POS", "pred_score_pos": 0.5620256662368774} +{"content": "OR WAIT null SECS\nCertain employees in your practice serve as keystones, but what happens if they can no longer perform their duties? Q: The manager of our four-provider practice is a key part of our team. If she became disabled, is there a way we could replace the income she helps us produce until we could find a replacement? A: “Key person” insurance is an effective way to provide a small- to medium-size business with funds to handle the disability or death of a key employee. A key employee is defined as someone who contributes significantly to the financial success of a business. In the case of a medical practice, the person may be a practice manager, a physician’s assistant, physician, or physician-owner.\nUnder this form of insurance, the employer pays the premium and owns the policy that insures the key employee. If the employee becomes totally disabled, the employer receives benefits to offset costs related to recruitment and training, temporary staffing, and short-term revenue replacement. A similar type of policy protects the practice in the event of a key employee’s premature death by providing a death benefit to the practice.\nPerhaps one of the best applications of key person disability insurance is in the case of a medical practice that is owned by a husband and a wife. In this situation, traditional disability buy-out insurance normally would be unavailable. With key person disability insurance, as long as a non-majority insured (someone who owns 50% or less of the practice) meets the definition of total disability, the policy owner receives either a lump-sum payment or a combination of monthly and lump-sum payments, depending the policy’s structure.", "pred_label": "__label__POS", "pred_score_pos": 0.5086337924003601} +{"content": "On 12 April, SIPRI, in cooperation with the Swedish Police Authority, organized a seminar discussion on ‘Policing Organized Crime in the Context of UN Peace Operations’.\nOrganized crime poses challenges to the security and governance of conflict-affected countries. It is an important source of revenue that enables armed groups to engage in conflict. As a society attempts to emerge from conflict, organized crime often facilitates corruption in the state administration and thrives due to weakened state institutions and capacities.\nThe discussion focused on measures that the United Nations can take to break the cycle of conflict, counter organized crime and strengthen state institutions.\nDan Smith, SIPRI Director, provided introductory remarks, alongside Ann-Marie Orler, Head of the International Affairs Division of the Swedish Police Authority.\nDuring the event, Dr Marina Caparini, Senior Researcher and Director of the SIPRI Governance and Society Programme, presented the findings of the new SIPRI Discussion Paper ‘UN Police and the Challenges of Organized Crime’. Download the publication here.", "pred_label": "__label__POS", "pred_score_pos": 0.5526766777038574} +{"content": "Contributions of Nanoscale Roughness to Anomalous Colloid Retention and Stability Behavior\njournal contributionposted on 28.08.2017, 00:00 by Scott A. Bradford, Hyunjung Kim, Chongyang Shen, Salini Sasidharan, Jianying Shang\nAll natural surfaces exhibit nanoscale roughness (NR) and chemical heterogeneity (CH) to some extent. Expressions were developed to determine the mean interaction energy between a colloid and a solid–water interface, as well as for colloid–colloid interactions, when both surfaces contain binary NR and CH. The influence of heterogeneity type, roughness parameters, solution ionic strength (IS), mean zeta potential, and colloid size on predicted interaction energy profiles was then investigated. The role of CH was enhanced on smooth surfaces with larger amounts of CH, especially for smaller colloids and higher IS. However, predicted interaction energy profiles were mainly dominated by NR, which tended to lower the energy barrier height and the magnitudes of both the secondary and primary minima, especially when the roughness fraction was small. This dramatically increased the relative importance of primary to secondary minima interactions on net electrostatically unfavorable surfaces, especially when roughness occurred on both surfaces and for conditions that produced small energy barriers (e.g., higher IS, lower pH, lower magnitudes in the zeta potential, and for smaller colloid sizes) on smooth surfaces. The combined influence of roughness and Born repulsion frequently produced a shallow primary minimum that was susceptible to diffusive removal by random variations in kinetic energy, even under electrostatically favorable conditions. Calculations using measured zeta potentials and hypothetical roughness properties demonstrated that roughness provided a viable alternative explanation for many experimental deviations that have previously been attributed to electrosteric repulsion (e.g., a decrease in colloid retention with an increase in solution IS; reversible colloid retention under favorable conditions; and diminished colloid retention and enhanced colloid stability due to adsorbed surfactants, polymers, and/or humic materials).", "pred_label": "__label__POS", "pred_score_pos": 0.8102735280990601} +{"content": "However, most business offers must include fiduciary collection. A copy of this amount must be submitted to the Securities and Exchange Commission (SEC) for corporate bonds for a total amount of at least $5 million. Corporate issues for less than $5 million, municipal bonds, and government-issued bonds are not required to file trust securities with the SEC. Of course, these liberated companies may choose to create a fiduciary indenture to reassure potential buyers of bonds, if not comply with a federal law. Almost all bonds contain subordination clauses that limit the amount of additional debt that the issuer can incur and require that all subsequent debts be subordinated to previous debts. In the absence of such restrictions, an issuer would theoretically be allowed to issue an unlimited amount of debt securities, which would increase the risk of default by bondholders. Many of the current rules for in-trust inlay were established by the Trust Indenture Act (TIA), a law passed in 1939 to protect bondholders and investors. Trust agreements should not be included in all debt contracts, as some government bonds disclose similar information (obligations and rights of the issuer and bondholders) in a document called a borrowing order. A trust also includes the characteristics of the loan, such as the maturity date, face value, coupon rate, payment plan, and purpose of the bond issue. A section of the trust intruder determines the circumstances and processes surrounding a failure.\nIndenture establishes a collective action mechanism under which creditors or bondholders can present themselves in a fair and orderly manner in the event of default by the issuer. A bond creditor must be aware of the right sequence of events and understand them so that he can take the right approach in the event of such a situation. Bonds are issued to lenders or investors to raise funds from a company or government agency. To issue a loan, the issuer uses a third-class agent, usually a bank or trust company, to represent the investors who purchase the loan. The agreement between the issuer and the agent is called a trust agreement. A trust is a legal and binding contract that is established to protect the interests of bondholders. The name and contact information of the agent are included in the document that highlights the conditions that the issuer, the lender and the agent must respect during the term of the loan. The section on the role of the agent is important because it clearly indicates how to deal with unforeseen incidents. For example, when a conflict of interest arises regarding the fiduciary role, the problem must be resolved within 90 days in some fiduciary services.\nOtherwise, a new representative will be recruited. Alliances of protection or restriction are highlighted in a trust agreement. For example, a trust collection may indicate whether an issued loan is available….", "pred_label": "__label__POS", "pred_score_pos": 0.694670557975769} +{"content": "Structural racism, implicit bias and discrimination in health care settings factor into longstanding health disparities in the U.S. The COVID-19 pandemic has exacerbated these inequities in Black and Latinx/Hispanic communities in particular. This event will examine the broader context of race and racism in health services and care, seeking to identify ways to address the devastating impacts on racial/ethnic minority patients and communities. This Forum will draw on data from a national poll released in 2021 by The Commonwealth Fund and the Harvard T.H. Chan School of Public Health and recently published in JAMA HealthForum. This poll was conducted to understand Black and Latino patients’ recent experiences with racism in health care.\nPresented in Partnership with The Commonwealth Fund and Jointly with STAT.", "pred_label": "__label__POS", "pred_score_pos": 0.9920872449874878} +{"content": "The current global crisis in mental health has seen psychiatry assume an increasingly integral role in healthcare. This comprehensive and accessible textbook provides an evidence-based foundation in psychiatry for medical students and serves as an excellent refresher for all mental health professionals. Written by medical school faculty and experts in the field, with comprehensive coverage from neurobiology to population health, this essential textbook is an invaluable guide to the evaluation, treatment and current understanding of the major disorders in psychiatry. The book introduces the basics of clinical assessment and all major modalities of evidence based treatment, along with topics often not covered adequately in textbooks such as gender and sexuality, and global mental health. Chapters are complemented by easy to navigate tables, self-assessment questions, and a short bibliography of recommended reading. An essential resource for medical students, trainees, and other medical professionals seeking a clear and comprehensive introduction to psychiatry.\nAdam M. Brenner - M.D. Editor-in-Chief, Academic Psychiatry, Professor of Psychiatry and Distinguished Teaching Professor, Vice Chair for Education and Residency Training Director in Psychiatry, University of Texas Southwestern Medical Center\n* Views captured on Cambridge Core between #date#. This data will be updated every 24 hours.\nUsage data cannot currently be displayed.", "pred_label": "__label__POS", "pred_score_pos": 0.9831387996673584} +{"content": "SkyTower, the tallest office building in Romania, has received the Gold DGNB certification for sustainable buildings, following the assessment by ÖGNI (the Austrian Society for Sustainable Real Estate Management).\nThe SkyTower Gold certification is issued for the Blue Building category and the assessment process was carried out in accordance with the European quality certification system DGNB (German Sustainable Building Council). This certification system aims to assess the sustainability of buildings’ environmental impact throughout their life cycle.\nThe SkyTower office building was evaluated according to the DGNB system considering six main areas: ecology, economy, socio-cultural and functional aspects, technology, processes, and location. Following the audit, SkyTower was awarded the Gold - Blue Building sustainability level, marking notable performances for integrated approach of operations, especially the technological aspect, the building ecology and the savings achieved in the operation process.\n“After nine years since its inauguration, SkyTower continues to demonstrate the functionality of this building’s visionary concept. We are honoured by this certification that further highlights our ongoing efforts to reduce the impact on the environment, with long-term focus. These results reflect consistent investment projects for development and reduction of resource consumption, but also our constant care for our community,” said Bernd Steingruber, Chief Technical Officer at RPHI Romania – the company that manages and owns SkyTower.\nPrior to this certification, in June 2021, SkyTower also received the LEED Platinum certification for Operations and Maintenance (O+M), which certifies buildings for best practices and measures environmental achievements during operations and maintenance.", "pred_label": "__label__POS", "pred_score_pos": 0.9113404154777527} +{"content": "In the second of two articles offering an overview of pharmacovigilance and its relevance to eye care practice, Dr Doina Gherghel focuses on the essential role of clinical trials in establishing the evidence base to support the evolution of practice strategy (C79112, one distance learning CET point suitable for optometrists and therapeutic optometrists)", "pred_label": "__label__POS", "pred_score_pos": 0.9998723864555359} +{"content": "PLANSPONSOR - August/September 2021 - 35 FINANCIAL WELLNESS | EMERGENCY SAVINGS\npeople to achieve success are more likely\nto be employer-based than individually\nbased. \"\nA growing number of employers has,\nfor all of the above reasons, begun to look\nat ways to incorporate emergency savings\nvehicles into their benefit programs.\nThose interested in implementing\nan emergency savings program should\nconsider the following:\n* There are several ways to implement\nworkplace emergency savings. A 2019\nresearch paper by academics at Harvard,\nYale and Brigham Young universities and\nthe Wharton School at the University of\nPennsylvania advocated for the creation of\nworkplace emergency savings accounts.\nThe paper outlined three possible routes\nemployers could take: after-tax employee\ncontributions to a 401(k); a \" deemed \"\nRoth individual retirement account (IRA)\nunder a 401(k) plan; and depository institution\naccounts outside a 401(k).\nThe first two methods offer the\nadvantage of an existing infrastructure\nthat makes it easy for employers to quickly\nset up a new program; however, it could\ntake slightly longer for employees to access\nthe funds in their account should an\nemergency arise. There may also be some\ncomplicated tax issues to consider if the\naccount generates taxable earnings.\nUsing a depository institution, on\nthe other hand, has the benefit of instant\naccess to and no limit on potential contributions;\nhowever, there is no favorable\ntax treatment for earnings. This may also\nbe a good option for employers that want\nto provide emergency savings but have\nno existing retirement benefit program,\nthe paper posited.\nCimini says, while plan sponsors\nshould think through whether it makes\nmore sense for them to go in-plan or outof-plan,\nthere is no right or wrong decision.\n\" There are some nuances, but both of\nthese options work, to the extent that they\nget folks saving something for a rainy day, \"\nhe says. \" It's up to the sponsor to choose\nwhich aligns better with its employees. \"\n* Plan design should emphasize\n\" Just getting employees over the hump\nwhere they get a text or a notification\nfrom their emergency fund provider\nthat says, 'Congratulations, you've\nreached $500,' is really important. \"\nliquidity. Unlike with retirement plans, the\ngoal of an emergency fund is to let participants\naccess the cash in the fund at any\ntime and not worry about losing their principal.\nOne viable design might be similar to\na common health savings account (HSA),\nwhich keeps a set dollar amount-say\n$2,000-in cash or liquid assets and then\nallows accountholders to invest a portion of\nany balance exceeding that amount, says\nMike Webb, a senior financial adviser with\nCAPTRUST in Newton, New Jersey.\n* The employer cost is relatively low.\nUnlike some other new benefit programs,\nthe time and money required by employers\nto get an emergency savings program up\nand running is relatively low, says Daniel\nBryant, president of national sales, retirement\nand private wealth at Sheridan Road\nFinancial, part of Hub International, in\nNorthbrook, Illinois.\nEach individual account may have\na nominal setup fee, which the employer\ncan either cover or pass through to\nparticipating employees. Beyond that, the\nemployer simply needs to connect the\naccount to its payroll system, which should\nhave already been done if it uses a 401(k)\nprovider. \" The benefits outweigh the\ncosts for all of these things, \" Bryant says.\n\" You're getting employee peace of mind\nand lowering their financial anxiety. Both\nof those things make the employee more\n'present' and more productive.\n\" Just getting employees over the\nhump where they get a text or a notification\nfrom their emergency fund provider\nthat says, 'Congratulations, you've\nreached $500,' is really important, \" Bryant\nobserves. \" For most of them, that's more\nthan they've saved in their entire life. And\nthen they want to make it $1,000. \"\nSome employers implement a match\nfor a retirement plan, which can require a\nsignificant investment for employers; the\nlower dollar amounts saved in an emergency\nsavings vehicle make it an easier\nfinancial lift for many employers. \" You can\ncome up with a low-cost matching system\nformula where the benefit significantly\noutweighs the cost, \" says Webb.\n* Education matters. As with most\nbenefits, the success of an emergency\nsavings account program hinges on the\neducation of participants into how it\nworks and the advantages they will enjoy\nby opting into it.\n\" It's helpful to look at all of your benefits\nand communicate them to employees\nholistically, \" says Dave Amendola, senior\ndirector, retirement at Willis Towers\nWatson in Fairfield, Connecticut. \" If you\nhave a benefit that is not necessarily tied to\nemergency savings but is aimed at helping\nthem address financial well-being-\nor well-being in general-tying those\ntogether and communicating the holistic\nvalue of the benefits is very helpful. \"\nAmendola suggests taking advantage\nof any vendor communication materials or\nprograms that might be useful.\n\" Education campaigns can target\nevery employee under age 30-they're the\nones who need this, \" he says. \" And provide\ninformation to new employees about the\nbroad strokes of financial planning. \"\nEmployers may find that some\nworkers are more receptive to benefits\ninformation than they were preCOVID-19,\nhaving seen first-hand how\nquickly financial emergencies can arise,\nBryant says. -Beth Braverman\nPLANSPONSOR.COM August - September 2021 35\nhttp://www.PLANSPONSOR.COM PLANSPONSOR - August/September 2021 Table of Contents for the Digital Edition of PLANSPONSOR - August/September 2021To Ensure All Are Well2021 PLANSPONSOR National ConferenceEquipped for Anything? The Security of SavingsTake a Load OffPLANSPONSOR - August/September 2021 - Cover1PLANSPONSOR - August/September 2021 - Cover2PLANSPONSOR - August/September 2021 - 1PLANSPONSOR - August/September 2021 - 2PLANSPONSOR - August/September 2021 - 3PLANSPONSOR - August/September 2021 - 4PLANSPONSOR - August/September 2021 - 5PLANSPONSOR - August/September 2021 - 6PLANSPONSOR - August/September 2021 - 7PLANSPONSOR - August/September 2021 - 8PLANSPONSOR - August/September 2021 - 9PLANSPONSOR - August/September 2021 - 10PLANSPONSOR - August/September 2021 - 11PLANSPONSOR - August/September 2021 - 12PLANSPONSOR - August/September 2021 - 13PLANSPONSOR - August/September 2021 - 14PLANSPONSOR - August/September 2021 - 15PLANSPONSOR - August/September 2021 - To Ensure All Are WellPLANSPONSOR - August/September 2021 - 17PLANSPONSOR - August/September 2021 - 18PLANSPONSOR - August/September 2021 - 19PLANSPONSOR - August/September 2021 - 2021 PLANSPONSOR National ConferencePLANSPONSOR - August/September 2021 - 21PLANSPONSOR - August/September 2021 - 22PLANSPONSOR - August/September 2021 - 23PLANSPONSOR - August/September 2021 - 24PLANSPONSOR - August/September 2021 - 25PLANSPONSOR - August/September 2021 - 26PLANSPONSOR - August/September 2021 - 27PLANSPONSOR - August/September 2021 - 28PLANSPONSOR - August/September 2021 - 29PLANSPONSOR - August/September 2021 - Equipped for Anything? PLANSPONSOR - August/September 2021 - 31PLANSPONSOR - August/September 2021 - 32PLANSPONSOR - August/September 2021 - 33PLANSPONSOR - August/September 2021 - The Security of SavingsPLANSPONSOR - August/September 2021 - 35PLANSPONSOR - August/September 2021 - Take a Load OffPLANSPONSOR - August/September 2021 - 37PLANSPONSOR - August/September 2021 - 38PLANSPONSOR - August/September 2021 - 39PLANSPONSOR - August/September 2021 - 40PLANSPONSOR - August/September 2021 - Cover3PLANSPONSOR - August/September 2021 - Cover4https://www.plansponsordigital.com/plansponsor/august_september_2021https://www.plansponsordigital.com/plansponsor/june_july_2021https://www.plansponsordigital.com/plansponsor/april-may_2021https://www.plansponsordigital.com/plansponsor/february-march_2021https://www.plansponsordigital.com/plansponsor/december-january_2021https://www.plansponsordigital.com/plansponsor/october-november_2020https://www.plansponsordigital.com/plansponsor/august-september_2020https://www.plansponsordigital.com/plansponsor/june-july_2020https://www.plansponsordigital.com/plansponsor/april-may_2020https://www.plansponsordigital.com/plansponsor/february-march_2020https://www.plansponsordigital.com/plansponsor/december-january_2020https://www.plansponsordigital.com/plansponsor/october-november_2019https://www.plansponsordigital.com/plansponsor/august-september_2019https://www.plansponsordigital.com/plansponsor/june-july_2019https://www.plansponsordigital.com/plansponsor/april-may_2019https://www.plansponsordigital.com/plansponsor/february-march_2019https://www.plansponsordigital.com/plansponsor/december_2018-january_2019https://www.plansponsordigital.com/plansponsor/october-november_2018https://www.plansponsordigital.com/plansponsor/august-september_2018https://www.plansponsordigital.com/plansponsor/june-july_2018https://www.plansponsordigital.com/plansponsor/april-may_2018https://www.plansponsordigital.com/plansponsor/february-march_2018https://www.plansponsordigital.com/plansponsor/december_2017-january_2018https://www.plansponsordigital.com/plansponsor/november_december_2017https://www.plansponsordigital.com/plansponsor/october_2017https://www.plansponsordigital.com/plansponsor/september_2017https://www.nxtbookmedia.com", "pred_label": "__label__POS", "pred_score_pos": 0.8180871605873108} +{"content": "Mentoring is a key part of career development, especially in emerging fields such as social entrepreneurship. Internet technologies have made it easier for novice social entrepreneurs to identify and connect with mentors online. Yet, we do not know the strategies mentors use to advise professionals navigating emerging fields. Knowing these strategies would allow us to create technologies for more effective career mentoring. This paper presents an expert model of career mentoring for novice social entrepreneurs. To build the model, we conducted a retrospective cognitive task analysis with 9 mentors who have at least 5 years of experience advising novice social entrepreneurs. We found that mentors help novice social entrepreneurs regulate career-related stress and make decisions about next career steps. Our findings suggest that further exploration of career mentoring strategies might allow designers to develop technologies based on the expert model, such as intelligent agents, to support and scale mentorship in emerging fields.", "pred_label": "__label__POS", "pred_score_pos": 0.8435747623443604} +{"content": "From Noah Ebije,\nKaduna Chairman, Senate Committee on Banking, Insurance and other Financial Institution, Senator Uba Sani, has said that the Asset Management Corporation of Nigeria (AMCON) and Nigeria Deposit Insurance Corporation (NDIC) are critical and strategic to Nigeria’s economic recovery and financial stability.\nSenator Sani noted that the NDIC is a strategic institution that the National Assembly must ensure it performs optimally, adding that the Corporation was established with the objectives of contributing to the financial system stability of the country.\nThe lawmaker spoke at separate retreats with AMCON and NDIC in Kaduna.\n‘From Thursday 15th July to Saturday, 17th July 2021, the Senate Committee on Banking, Insurance and other Financial Institutions which I chair held separate retreats with the Asset Management Corporation of Nigeria (AMCON) and Nigeria Deposit Insurance Corporation (NDIC) at Bafra International Hotel, Kaduna,’ he stated.\n‘The well attended and action-oriented retreats had as themes “Financial System Stability: A Panacea for Sustainable Economic Growth and Development – The Role of NDIC,” and “Asset Recovery as a Contributor to Economic Growth and Development: Challenges and Prospects of Asset Recovery in Nigeria – The AMCON Experience.”\n‘In my remarks at the two retreats, I highlighted the critical and strategic importance of AMCON and NDIC to Nigeria’s economic recovery and stabilisation efforts, especially in ensuring financial stability. “NDIC is a strategic institution that the National Assembly must do all in its powers to ensure it performs optimally. NDIC was established with the objectives of contributing to financial system stability; protecting small and less financially sophisticated depositors by providing an orderly means of resolution and compensation in the unlikely event of failure of their insured financial institutions.\n‘In respect of the Asset Management Corporation of Nigeria (AMCON), I stated that “since the establishment of AMCON in 2010, conscious and deliberate efforts have been made by the National Assembly to strengthen its legal and institutional frameworks to enable it to contribute optimally to our economic recovery and stabilisation efforts. The National Assembly amended the Act in 2015 and 2019. In response to the impact of the Covid-19 on AMCON’s policies and processes, the Senate amended the Act in 2021 by extending the tenor of the Resolution Cost Fund and also empowered AMCON to access the Special Tribunal established by the BOFIA, 2020 for dealing with financial related matters,’ Senator Sani said.\nIn his remarks at the retreat, the Managing Director of NDIC, Mr Bello Hassan said he was pleased to inform retreat participants that “the Corporation in collaboration with other key stakeholders have been proactive in managing the risks associated with cyber insecurity. The NDIC has taken important steps at ensuring the safety of the Nigerian banks and the protection of depositors in line with its mandate. For instance, the NDIC in 2020 established a ‘FinTech and Innovation Unit’ to effectively respond to the challenges of cyber threats among other challenges of the FinTech Innovations.\n‘Also, the Corporation had used this platform to commence supervisory measures for digital banks, enhance existing consumer protection measures, especially as regards digital deposit, through enhanced collaboration with other safety-net players.’\nIn his contribution, Mr Ahmed Kuru, AMCON Managing Director revealed that the foremost asset recovery institution has made remarkable progress in its debt recovery efforts.\nAMCON has so far recovered about N1.4 trillion naira. I am optimistic that if AMCON maintains the current debt recovery and asset disposal momentum, in 15 years it will fully discharge its obligations to the Central Bank of Nigeria (CBN)\nDiscussions at the 2-day retreats were very lively, revealing and forward-looking. Experiences and challenges were shared.\nThe retreat deepened Committee members understanding of the strategic roles of AMCON and NDIC in the economy, particularly the financial system.\nNDIC and AMCON shared their thoughts with members on ways they can be strengthened legally and institutionally to ensure optimal performance.\nThe Committee assured AMCON and NDIC of their commitment to deepening its partnership with the two important institutions.\n‘Participants went away with some actionable points, which if followed and fully implemented by Committee members, NDIC and AMCON, will reposition the two strategic institutions and help quicken our economic recovery,’ Senator Sani added.\n100% Natural Herbs to Finally End Premature Ejaculation and Weak Erection. Click here.", "pred_label": "__label__POS", "pred_score_pos": 0.8494259119033813} +{"content": "Thursday, October 21, 11-12:15 pm Join us for an honest and engaging conversation about moving beyond resilience.\nWe know that not all domestic and intimate partner violence is acknowledged or responded to equally — and that some survivors and victims go unrecognized altogether.\nWe recognize both the importance and limits to surviving violence. During this event, we will discuss resilience and the urgency required to create equitable pathways for safe and thriving communities for all. MISSION: YWCA Richmond is dedicated to eliminating racism, empowering women, and promoting peace, justice, freedom and dignity for all. VISION: We will transform individual lives and our community by creating access to opportunities, strengthening resilience, and advancing equitable systems for lifelong success. Get Help\nIf you need help now call\n804-612-6126. Or click to find out more about other resources. 40 years, 300women in the Greater Richmond area have been recognized at the Outstanding Women Awards for their exceptional leadership and contributions 96%parent participation in The Sprout School conferences, field trips, volunteer opportunities, and donation drives", "pred_label": "__label__POS", "pred_score_pos": 0.6173431873321533} +{"content": "In 9 experiments, participants were presented with a series of 4 novel items, followed by an immediate or delayed probe recognition test. Delaying therecognition test reduced performance on the final item, when the interpresentation intervals (IPIs) were kept constant (Experiments 1A-1G), and alsowhen the IPIs were varied (Experiments 2A-2B). Only 1 experiment reported any evidence of increased primacy with delay when the IPIs were kept constant, but this result failed to replicate. Neither Experiment 2A nor 2B provided evidence of increased primacy with test delay or any effect of IPI on recency. However, Experiment 2A showed a deficit at the first serial positionwhen followed by a short IPI. These results do not support the predictionsof the dimensional distinctiveness model but are broadly compatible with established information-processing models of visual memory.", "pred_label": "__label__POS", "pred_score_pos": 0.7974785566329956} +{"content": "I recently joined a group of four other talented Queers in STEMM (Science, Technology, Engineering, Maths and Medicine) to form the first QueersInScience Queensland Chapter. All of us have a common goal - helping LGBTQIA+ feel supported and safe in STEMM, educating (collaboratively) those that have influence, and fostering healthier work places and industries for LGBTQIA+ people in STEMM. We are hosting our inaugural Queensland QueersInScience event tonight so I thought it would be a great idea to introduce everyone in our team here!\nAs Australians try to maintain social engagement during self-isolation, citizen science offers a unique opportunity. Citizen science allows everyday people to use technology to unite towards a common goal – from the comfort of their homes. From online protein folding games to backyard birding, citizen science is now offering a chance to contribute to research on the coronavirus pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.9626495242118835} +{"content": "Abstract\nIndividuals often mutually experience a stimulus with a relationship partner or social group (e.g., snacking with friends). Yet, little is currently understood about how a sense of coexperiencing affects hedonic judgments of experiences that unfold over time. Research on the shared attention state has suggested that hedonic judgments are intensified when individuals coexperience a stimulus (vs. experiencing it alone), and other related work has found that the social environment influences hedonic judgments in shared (vs. solo) experiences. Although this past work has focused on judgments of single instances of a stimulus, the present work examines how coexperience affects hedonic judgments of stimuli over time. This work documents the 'collective satiation effect' wherein satiation-a diminished enjoyment of pleasant stimuli with repeated experience-is accelerated by a sense of coexperiencing the stimulus with others. We propose that this happens because shared attention makes the repetitive nature of the experience more salient, by promoting and incorporating thoughts of others also repeatedly having the same shared experience. Five studies document the collective satiation effect, support the proposed mechanism, and show moderators of the effect. Taken together, this research contributes to an understanding of how the social environment influences the experience of hedonic stimuli, which has broad implications for the value individuals place on the time that they spend with others.\nBibliographical notePublisher Copyright:\n© 2018 American Psychological Association.\nCopyright:\nCopyright 2018 Elsevier B.V., All rights reserved.\nKeywords Hedonic judgments Satiation Shared experiences Social context", "pred_label": "__label__POS", "pred_score_pos": 0.7279045581817627} +{"content": "Antisocial behaviour orders (ASBOs) became available from 1 April 1999. Data on the number issued currently covers the period to the end of 2007. These data are not available below Criminal Justice System (CJS) area level.\nData on the number of ASBOs issued held by the Office for Criminal Justice Reform do not include information detailing the specific nature of the antisocial behaviour which resulted in the court issuing the ASBO. This could only be determined by examining individual court files which could be achieved only at disproportionate cost.", "pred_label": "__label__POS", "pred_score_pos": 0.9217402338981628} +{"content": "Champagne taste, beer budget: The new poor’s incongruent capital and consumption\njournal contributionposted on 05.09.2019, 17:04 by Wei-Fen Chen, Michelle R. Nelson\nThis study examines the shopping preferences of “new poor” consumers who have incongruent capital: lower economic capital and higher noneconomic capital. The new poor exemplify consumers with ambiguous and fragmented identity; thus, they do not fit marketers’ static categorization of consumer segments. In the marketplace, these consumers must compromise between their upper-class taste and lower-class earnings. Taking a Consumer Culture Theory approach to examine consumers’ identity projects in social inequality, we conduct 20 interviews among self-defined new poor consumers in the United States and Taiwan to explore how their dynamic social class consciousness is reflected in everyday consumption. The findings suggest that new poor consumers perform “compromised ideal consumption” in which they strategically interpret and wield their remaining capital to signal social class differences, while employing adaptive and active capitalization acts to access goods that should have been beyond their price range. The findings illuminate how incongruent, devalued capital reproduces social stratification in the context of downward mobility.", "pred_label": "__label__POS", "pred_score_pos": 0.6364896297454834} +{"content": "Three decades is a long time—long enough to experience the consistent faithfulness of our God. He has been with us through every twist and turn. God continues to empower us to be influencers who can help others discover His love and grace. Today we celebrate our first 30 years! God’s past faithfulness reminds us He can be trusted for the future. So today, with His help, we begin Another 30!\nDespite our romanticism about the early church, they had their fair share of problems - favoritism, theological arguments, and divisions (to name a few). Yet there remained a vision of an abundant church - full of energy, unity, and life. While the church today...\nA believer's identity is in Christ. In Him we find true life, meaning, and purpose. Yet, it is common for believers to take their eyes off of Jesus and begin substituting other things in His place. We look for other ways to identify ourselves often choosing how we...\nIt shouldn’t surprise us that through the centuries, superstitions arise and thrive even among well-meaning church people. Most of these superstitions are based on a desire for a kind of good luck charm in a life filled with uncertainty and hardship. Even the practice...", "pred_label": "__label__POS", "pred_score_pos": 0.9712687730789185} +{"content": "Abstract Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due to online event limitations.\nCancer is a chronic disease that impacts function, and OT can help these individuals re-engage in meaningful occupations. This exploratory study evaluated occupational performance challenges identified by women impacted by cancer and their relationship to demographics. Results showed that challenges were identified in all areas of occupation and that age, race, and medications did not impact occupational challenges, highlighting a need for OT to intervene in this population across demographics.\nPrimary Author and Speaker: Hannah Goldberg-O’Neil Additional Authors and Speakers: Colleen Maher, Rochelle Mendonca", "pred_label": "__label__POS", "pred_score_pos": 0.9334105253219604} +{"content": "Abstract\nAbstract: Policy and research on European cyber-security remains formative compared to leaders in the field like China and the United States. This article evaluates the European Union (EU) as a cyber-security actor, asking fundamental questions concerning the EU's combination of prominence and obscurity, especially its limitations and prospects. Who and what is going to dominate the European response to cyber-security in the future? These questions are examined within the larger framework of liberal intergovernmentalism. The EU also is compared to the North Atlantic Treaty Organization (NATO), a point of reference to further understand the limitations and challenges ahead for the EU. Two major factors limit the EU as a cyber-security actor: its intergovernmental character, and the lack of collective vision on cyber-security with the EU and between member states. To play an important role in shaping cyberspace and cyber-security, the EU cannot treat the internet as simply a communication tool or trading platform. Cooperation and capacity-building measures are needed to allow EU member states to surpass mere coordination of their respective national cyber-security strategies. To succeed as a cyber-power, the EU should adapt new and different forms of cyber-power, from the compulsory through the institutional, to the structural and productive. Otherwise, coordination of national strategies for cyber-security of EU member states is the most the EU as an actor can aim for.\nScopus Subject Areas Political Science and International Relations", "pred_label": "__label__POS", "pred_score_pos": 0.5000894069671631} +{"content": "The director of the Pathological Institute of the University of Heidelberg, Peter Schirmacher, has carried out over forty autopsies on people who died within two weeks of receiving a Covid-19 vaccine and has expressed alarm over his findings.\nSchirmacher stated that 30 to 40 per cent of people he examined died from the vaccine and that in his opinion, the frequency of fatal consequences of vaccinations is “underestimated.”\nFollowing his findings, Schirmacher has called for more autopsies of vaccinated people to further determine whether the vaccines are linked to deaths. He has warned that the high number of unreported cases of vaccination deaths is partially due to the fact that “pathologists do not notice anything about most of the patients who die after and possible from a vaccination.”\nDespite raising the alarm surrounding the vaccines, many have criticised Schirmacher’s conclusions, with the Paul Ehrlich Institute calling the director’s statements “incomprehensible.” The Chancellor’s lackey, senior German immunologist Thomas Mertens dismissed the findings right away: “I don’t know of any data that would allow a justifiable statement to be made here and I am not assuming an unreported number.”\nThe immunologist Christian Bogdan from the Erlangen University Hospital, a member of the Standing Vaccination Commission (STIKO), also contradicted Schirmacher’s assumption of a “high number of unreported vaccination complications or even deaths.”\nDespite the criticism, Schirmacher did receive support from his own ranks, and the Federal Association of German Pathologists stated that more autopsies of vaccinated people who died within a certain time frame after vaccination should be performed.", "pred_label": "__label__POS", "pred_score_pos": 0.5037640333175659} +{"content": "In September, natural gas prices soared, with European gas prices reaching an all-time high as demand driven by the energy transition continues to significantly outpace supply.\nThis is expected to increase further as demand is expected to exceed pre-covid levels by 7% by 2024. Natural gas will continue to be the transitional fuel for the near future, but producers are limiting investments in new supplies and few other short-term alternatives. , the requirement for cleaner energy resources is at an all time high to help meet environmental goals. Ahead of COP26, Piper Sandler summarizes the emerging themes of mergers and acquisitions (M&A) of the energy transition.\nFrom the UKCS perspective, the macro picture is positive. The number of emerging operators entering the region continues to increase, with substantial capital being allocated to projects within the UKCS. Supported by a well-understood regulatory regime and existing infrastructure, UKCS is poised to become a leading global integrated clean energy hub. This is also supported by the UK government’s major commitment to building a hydrogen economy and establishing a strong competitive position globally. As a result of these factors, UKCS has established itself as a highly respected basin from a global perspective, highlighted by significant ongoing activity in the renewable energy sector and an expectation that this will continue to grow. ‘accelerate in the short term.\nIn the mergers and acquisitions sector, oil service providers (OFS) continue to make great strides in the energy transition space, with many players announcing important strategic moves to position themselves in new markets. This has effectively generated a new “category of transactions” within the energy industry, where transactions related to the energy transition can be specifically mapped within the OFS sector.\nHowever, this is not a “one size fits all” strategy, which is why OFS suppliers continue to design different strategies to participate in the energy transition that highlight their strengths. This is evident in the offshore wind industry, where many offshore installation service providers have effectively transitioned and moved their services into this high growth industry. These newly formed energy service providers will play a pivotal role in providing the technology and services necessary to achieve the Net Zero goals, while significantly reducing the cost bases in the oil and gas and renewable energy sectors. With the scale, management expertise, financial resources and global footprint that OFS providers can utilize, many will be successful in making this transition.\nPiper Sandler continues to see a more diverse customer base and transaction base, with exposure to the entire energy sector. Energy transition, decarbonization, technology and diversification have all become key themes in recent deals, with multiple pending deals sharing similar goals. Piper Sandler remains committed to the global energy industry and continues to stay at the forefront of industry trends, drivers and developments.\nRecommended for you\n“Critical Junction”: Sir Ian Wood and Maggie McGinlay discuss COP, Torry and Aberdeen energy transition\nSource link", "pred_label": "__label__POS", "pred_score_pos": 0.947678804397583} +{"content": "The minority investment in Prometheus Fuels, focused on developing cost-efficient, carbon-neutral eFuels, will support Maersk’s work to execute on the strategy to decarbonise marine operations.\naersk expects several fuels to exist alongside in the future fuel mix and has identified 4 potential fuel pathways to decarbonization:\nBiodiesel; Alcohols; Lignin-enhanced alcohols; Ammonia.\nThe investment supports Maersk’s efforts with electrofuels which include alcohols produced from renewable energy. Along with biodiesel, alcohols including green methanol are feasible fuel technologies already today.\nElectrofuels are expected to play a key role for the decarbonisation of shipping and, if scaled successfully, Prometheus Fuels’ technology will address a key constraint for carbon based electrofuels – namely the cost competitiveness of direct air capture\nMorten Bo Christiansen, Head of Decarbonisation, A.P. Moller – Maersk.\nMaersk also expects synthetic alcohols and other electrofuels to play a big role in the decarbonisation of shipping, due to its long-term scalability advantages compared to biobased fuels. Produced from renewable energy and water and ambient CO2 from direct air capture, it has the potential to offer infinite availability regardless of geographic scope.", "pred_label": "__label__POS", "pred_score_pos": 0.9898458123207092} +{"content": "Oklahoma Excel, which is part of the Champions of Excellence initiative, is a yearlong professional learning experience open to all PK-12 teachers. Teachers within a district form teams and join a Networked Improvement Communities (NIC) within a specific content area. Members of the NIC engage in continuous improvement cycles in their classrooms to implement and refine high-leverage, evidence-based instructional strategies. Teachers and teacher leaders who participate receive between 45 and 70 hours of job-embedded, sustained, data-driven, classroom-focused professional development. Participants also have access to on-site instructional coaching, resources, and tools in an effort to bring about lasting improvement in their schools.\nDawn Irons has been with the Oklahoma State Department of Education (OSDE) since 2017. She started out in the Office of School Support where she served as a School Support Specialist. After a year Dawn moved to the Office of Curriculum and Instruction as the Director of Oklahoma Excel. In her current role, as the Executive Director of Champions of Excellence and Networked Improvement Communities, Dawn oversees all programs related to job-embedded professional learning and networked learning initiatives. Prior to joining OSDE, Dawn worked in Oklahoma City Public School's Professional Development Department as an instructional coach coordinator. Along with her colleagues, Dawn helped established an instructional coaching program in the largest school district in the state. Before moving to Oklahoma, Dawn spent ten years working as an elementary classroom teacher, peer evaluator, and instructional coach in Tampa, Florida. Dawn holds a bachelor's degree in elementary education and a master's degree in organizational leadership, instructional design, and organizational training. Dawn resides in Oklahoma City with her husband and two dogs. When she's not working, Dawn enjoys traveling, watching documentaries, reading historical fiction novels, and cooking.\nSusan Wray is a twenty-six-year veteran science teacher who is native to Oklahoma. Prior to working for the Oklahoma State Department of Education, Susan taught elementary and middle-level science at Oakdale Public Schools from 1997-2019 and Broken Arrow Public Schools from 1992-1997. While at Oakdale, Susan was instrumental in implementing a STEM program, overseeing science curriculum, and developing a spirit squad. Throughout the state, Susan has been a leader in science-- presenting at the Oklahoma Science Teacher Association conference, developing Frameworks for Science, and participating in Oklahoma science assessment development. She has dedicated herself to becoming a life-long educator, learner, and leader.\nGena Barnhill has been teaching elementary math for 15 years. She spent 13 years developing her skills at Rollingwood Elementary in Putnam City and 2 more years at Lakeview Elementary in Yukon. During this time, she worked on district curriculum development and training, the Oklahoma state math frameworks, and the math and science OSTP Item Review Committee. She has also presented at state math and science conferences. She received the 2018 Presidential Award for Excellence in Math and Science Teaching and achieved her National Board Certification in 2020. Gena graduated from the University of Oklahoma with her Bachelor's degree and the University of Central Oklahoma with her professional teaching certificate.\nAndrea Chrisman joined Teach for America in 2008 and moved to the Bay Area to begin her teaching career. She spent 8 years teaching literacy at some of the highest performing schools in San Jose and San Francisco, working in predominantly underserved communities. She recently returned home to Oklahoma and has spent the last 2 years teaching reading on the south side of Oklahoma City. This past year she served her school as the 4th-grade team lead and the ELA content lead. Andrea lives in Oklahoma City with her cat, Minnow, and when she isn't working, she enjoys reading thriller books, cooking, and listening to her records.\nMagdalena Grifaldo has served as an early childhood educator in Southwest Oklahoma City for 5 years. Prior to working for the Oklahoma State Department of Education, Lena taught pre-kindergarten and kindergarten at Santa Fe South Schools. While at Santa Fe South, Lena led the early childhood education teams for both pre-kindergarten and kindergarten, coached teachers through fifth grade in creating and implementing strong mathematics practices in the classroom, and played a critical role in establishing the school site's after school program. After her corps service with Teach For America, Magdalena pursued and graduated with honors from the University of Central Oklahoma with a M.Ed in Educational Leadership in 2019 and attended Barnard College for her undergraduate studies. She remains involved and connected to the Teach For America and greater OKC community by serving as a board member for both the Alumni and Collective Boards for the TFA OKC region. Outside of work, you would find her gardening at home, visiting local restaurants and businesses, and catching up on the newest series. Born and raised in Dallas, TX, she currently resides in OKC with her husband and two cats.\nTo learn more about the foundational research that has shaped the vision of this project, explore the database below.", "pred_label": "__label__POS", "pred_score_pos": 0.7771148681640625} +{"content": "Stephen Hall discusses the golden rules for design\nWEIGHT is often used for process monitoring and control, especially for storage tanks, bins, silos, mixing vessels, and batch reactors. Typically, three or four load cells are mounted beneath the vessel, and a summing instrument transmits the combined measured weight to the process control system. The load cells are typically installed under the tank legs or between side-mounted lugs and the steel support structure.\nAccurate weight measurements are obtained when extraneous forces are eliminated or compensated for. Extraneous forces may be generated from lateral loads, thermal expansion or contraction, or bending moments from attached components and piping. The extra forces might be compensatable through the taring step, where the load cell system is zeroed prior to adding the measured load. But for this, the forces would have to remain constant over the duration of the measurement. Generally, the design should anticipate and mitigate spurious forces.\nMettler Toledo\nAccurate: Tank on load cells with calibration weights and digital display\nHere are some tips for load cell design and installation:\nUse compression load cells for tanks, not shear beams. Compression load cells are relatively unaffected by non-vertical loads because they float beneath the tank. If a tank experiences thermal expansion, its supporting surface slides across a compression load cell and therefore maintains a vertical force. Shear beams are bolted to the tank; thermal expansion results in a bending moment that the load cell interprets as added weight. Use or specify mounting kits for the load cells and ensure that they are installed to absorb side forces. Provide a rigid support structure. The load cell support and vessel system should be designed to eliminate flexing that would affect the readings. If the tank sits on long legs, the load cells should be installed near the top of the legs, not at the bottom. Provide adequate stiffening and cross-bracing. If multiple load cells are used, ensure they carry approximately equal load. Isolate the vessel system from its surroundings. Ensure that appurtenances float with the tank; avoid fixed connections to external structures. For instance, ladders should be attached to the tank and not the support structure, or attached to the support structure with a small gap between the ladder and tank. Ensure that piping and conduit connections are flexible. Although many engineers routinely specify flex connections, such as hoses or bellows, for this purpose, adequate flexibility is usually obtainable with careful routing and support of the piping. The goal is to eliminate extra horizontal or vertical forces from the piping. Taking potential thermal expansion and contraction of the vessel into account, piping bending moments can be calculated between the connection point and the closest rigid pipe support. The bending moments translate into vertical and horizontal forces imposed on the tank; their magnitude determines the potential effect on the load cell reading and may be inconsequential when taken as a percentage of the total mass of the vessel system. For tanks, provide attachment points for hanging weights when the load cells are calibrated. Alternatively, ensure that standard weights can be placed on top of the tank. If the standard weights weigh less than the maximum load, then the load cells are calibrated in steps. The weights are placed onto an empty tank to calibrate the first point. The weights are removed, and water is added to bring the display to the first calibrated point. The weights are again placed onto the tank and the second point is calibrated. This procedure continues until the maximum weight is calibrated. Because the weight of each water addition is subject to the accuracy of the load cells, this stepwise calibration method introduces error into the overall calibration.\nYou can calculate the force that is exerted by connected piping, using\nEquation 1.", "pred_label": "__label__POS", "pred_score_pos": 0.5044735670089722} +{"content": "Methanol Institute Position on Energy Tax Directive Revision – MI offers full support for the European Commission’s proposed revision of the Energy Taxation Directive under the Fit for 55 packages. The central feature of the revision introduced in July is the restructuring of EU taxation of fuels to reflect actual energy content and environmental performance, rather than volumetric weight.\nMeasuring Maritime Emissions – The Methanol Institute (MI) is calling on maritime policy-makers to adopt a ‘well-to-wake’ approach in GHG accounting of fuels to support the decarbonization of maritime transport. MI believes an approach that accounts for GHG emissions of the fuel’s entire value chain is essential to stimulate the uptake of renewable fuels that can drive the maritime industry’s energy transition.\nMethanol Institute’s Fit for 55: Key Implications for Liquid Fuels – MI hosted a webinar with industry experts from FuelsEurope, OCI/BioMCN, and the European Commission, to present the role of liquid fuels under the Fit for 55 package.", "pred_label": "__label__POS", "pred_score_pos": 0.927208662033081} +{"content": "Authors\nPredicting the nature and outcome of reactions using computational methods is a crucial tool to accelerate chemical research. The recent application of deep learning-based learned fingerprints to reaction classification and reaction yield prediction has shown an impressive increase in performance compared to previous methods such as DFT- and structure-based fingerprints. However, learned fingerprints require large training data sets, are inherently biased, and are based on complex deep learning architectures. Here we present the differential reaction fingerprint \\textit{DRFP}. The \\textit{DRFP} algorithm takes a reaction SMILES as an input and creates a binary fingerprint based on the symmetric difference of two sets containing the circular molecular n-grams generated from the molecules listed left and right from the reaction arrow, respectively, without the need for distinguishing between reactants and reagents. We show that \\textit{DRFP} outperforms DFT-based fingerprints in reaction yield prediction and other structure-based fingerprints in reaction classification, reaching the performance of state-of-the-art learned fingerprints in both tasks while being data-independent.", "pred_label": "__label__POS", "pred_score_pos": 0.9946614503860474} +{"content": "Increasing competition and rapid technological change require leaders to make swift and effective decisions. Rally drivers, registering many victories, are always accompanied by a good co-driver. Likewise, to monitor and manage his cash flow, the business manager, often alone in charge, is advised to rely on a trusted interlocutor, a CPA chartered accountant.", "pred_label": "__label__POS", "pred_score_pos": 0.9995470643043518} +{"content": "Continuation of our conversation with Melissa May Borja, Ph.D., about the Virulent Hate Project, an interdisciplinary research initiative that studies anti-Asian racism and Asian American activism during the COVID-19 pandemic.\nLater we celebrate the activism of Grace Lee Boggs and her organizing work with diverse communities.\nVirulent Hate Project\nKey findings from the new report include:\nOf the 1,023 unique anti-Asian hate incidents analyzed, 66% (679 incidents) involved anti-Asian harassment and vandalism that targeted individuals or groups. Approximately 33% (344 incidents) involved stigmatizing and discriminatory statements, images, policies and proposals made by individuals or groups that reproduced anti-Asian stereotypes and harmed Asian Americans as a community.\nAnti-Asian harassment affected Asian Americans of all ages, ethnic groups and genders, although the harassment was not experienced evenly across demographic groups. Women were the victim in 65% of anti-Asian harassment incidents, and Chinese Americans experienced nearly 58% of the harassment incidents reported in the news. Available information suggests the perpetrators of anti-Asian hate incidents were predominantly male and disproportionately white. Among politicians who made stigmatizing statements and supported discriminatory policies and proposals, the primary perpetrators were white, male and affiliated with the Republican Party. Incidents of anti-Asian harassment were reported in the news in 40 states and the District of Columbia. The majority (67%) of anti-Asian harassment incidents occurred in businesses, streets and public transit. Anti-Asian hate incidents reported in the news peaked in March and April 2020, even as most Americans limited their visits to public places due to pandemic-related lockdown and shelter-in-place policies.", "pred_label": "__label__POS", "pred_score_pos": 0.8183845281600952} +{"content": "Are hydrogel sports drinks superior to conventional sports drinks to enhance marathon performance? Based on a recent article by Roweet al., published July 2021 TITLE: ‘’Glucose and fructose hydrogel enhances running performance, exogenous carbohydrate oxidation, and gastrointestinal tolerance\" DOI link: https://doi.org/10.1249/MSS.0000000000002764 What did this study look at?\nOver recent years so-called hydrogel sports drinks have been promoted to be superior to conventional sports drinks to enhance endurance exercise performance. Hydrogel carbohydrate solutions are produced by the addition of sodium alginate and pectin, which may facilitate gastric emptying. However, strong evidence to prove such claims is currently lacking.\nTherefore, Row and co-workers from Leeds University in the UK compared the effect of a hydrogel versus non-hydrogel carbohydrate drink on metabolism and performance during a >2h running trial. Eleven well-trained runners (marathon PR <2h40min) participated in a 2h steady-state run at ~70% of VO2max whereafter they performed a 5 km all-out run (~20 min). All runners participated in three trials with a 1-week interval. In two trials they received an 18% glucose:fructose solution (2:1 ratio) either as a hydrogel formulation (CHO-H) or as a conventional non-hydrogel solution (CHO). In another trial they received a carbohydrate-free placebo (PL) drink. They ingested a 200 mL bolus before the start and then 100 mL every 15 min, delivering 90 g of carbohydrates per hour during the steady-state exercise in CHO-H and CHO. No drinks were given during the final 5 km run. Carbohydrate and fat oxidation rates, gastrointestinal (GI) symptoms, and performance in the 5 km run were measured.\nWhat did the study show?\nThe relative contribution of oral carbohydrates to total energy production during the 2h steady-state run in CHO-H (32%) was ~3% higher than in CHO (29%). There was no difference in muscle glycogen breakdown between the two CHO conditions. The overall incidence of GI symptoms was slightly higher in CHO than in CHO-H. Compared with PL , CHO-H improved performance in the 5 km run by 7.6%, versus 5.6% in CHO, which on average resulted in a ~25 sec faster finishing time in the former condition.\nWhat is the importance of this finding for sports performance?\nThe current study for the first time demonstrates that a concentrated 18% hydrogel solution, increased muscle carbohydrate utilization, decreased the incidence of GI symptoms, and enhanced performance compared with a conventional 18% energy sports drink. However, carbohydrate intake rate during exercise was 50% higher than recommended for exercise events lasting <2h30min (60g/h). Therefore, the benefit of hydrogel carbohydrate solutions compared to conventional isotonic or hypertonic sports drinks, when being used according to the prevailing scientific recommendations for carbohydrate and fluid intake in endurance exercise, remains to be proven.", "pred_label": "__label__POS", "pred_score_pos": 0.6550259590148926} +{"content": "A study conducted in Israel compared reinfections and breakthrough infection in people who had recovered from COVID-19, those who hadn't had the virus but received the vaccine and a group that had experienced both of these events.\nThere has been a lot of speculation about whether those who have previously contracted COVID-19 developed an immunity to the virus. It was assumed that this was the case as this was the initial hypothesis involving herd immunity. Frequently, a certain percentage of the population has to be able to get an illness for it to spread. It the number is lower than this percentage the disease will spread at an increasing rate while if it's higher then the number of people contracting the illness will decrease.\nHerd immunity happens in the latter case, when a large enough proportion of the population becomes immune to the disease which will eventually eliminate its abiltiy to spread. This protest the entire population not just those who are immune to the disease. Herd immunity can happen when enough individuals have recovered from an illness and developed antibodies against future infection if they are again exposed\nThere are obvious limitations to relying on herd immunity from natural infection alone. These include the fact that a certain number of people will die from the virus and the fact that at least 70% of the population in the U.S. would need to have recovered from the virus and developed antibodies in order to achieve herd immunity in the first place.\nThe other issue is that for herd immunity to occur, people must actually develop antibodies that prevent them from developing the disease again. When the pandemic first began, it was assumed that you couldn't get the virus twice. However, this was quickly disproven as individuals began experiencing reinfections. While the rates of the disease in those who had previously contracted and recovered from it were lower, than in those who'd never had it before, it was still possible for those with the antibodies to become reinfected.\nHerd immunity can also be developed by vaccinating enough of the population to eliminate transmission. But while the vaccine effectively decreases the liklihood of severe illness, hospitalization and death, it also doesn't provide complete immunity. Additionally, there are the problems of vaccine hesitancy and refusal, and widely circulating variants that may be less responsive to the vaccine.\nIt's come to be accepted that herd immunity is unlikely because of these factors. Studies have turned to determining whether there are things we can learn from those who have recovered the virus that will help improve our ability to prevent it's transmission. A recent large scale study in Israel examined differences in reinfection and breakthrough infection rates for those who had recovered from the virus but hadn't been vaccinated, those who had received the Pfizer two dose vaccine but hadn't had the virus and those who had experienced both of these events.\nSubjects were 778,658 individuals. Of those, 62,883 were unvaccinated and had recovered from COVID-19, 673,676 were fully vaccinated with the Pfizer vaccine and hadn't been exposed to the virus, and 42,099 were vaccinate and had recovered from the virus prior to vaccination.\nIt was found that participants who were vaccinated but had not been exposed to COVID-19 had a significantly increased risk of becoming infected with the Delta variant compared to unvaccinated individuals who had recovered from the virus. Vaccinated individuals also had a much higher risk for symptomatic COVID-19 and for requiring hospitalization due to breakthrough infections.\nParticipants who had been recovered from the virus and were vaccinated with with one dose of vaccine were found to have greater protection against the Delta variant than those in the other two groups.\n(In March, 2021 the Israeli Ministry of Health revised its guidelines and allowed individuals over the age of 16 who had recovered from the virus to receive one dose of the Pfizer vaccine, after at least a 3-month-interval had passed since the date of infection. Prior to June 2021, Israel would not allow anyone under the age of 16 to receive a vaccination.)\nThis study demonstrated that the resistance that comes from having the virus provides longer lasting and more robust protection against infection, developing symptomatic illness and required hospitalization caused by the Delta variant, compared to the resistance that results from the Pfizer two-dose vaccine. Individuals who were previously infected with COVID-19 as well as given a single dose of the vaccine gained additional protection against the Delta variant above what was experienced by those with only immunity conferred from having the virus.\nThe investigators note that these findings may not necessarily generalize to individuals who had recieved a different vaccine or to variants other than the Delta variant.\nThis is original content from NewsBreak’s Creator Program. Join today to publish and share your own content.", "pred_label": "__label__POS", "pred_score_pos": 0.8762995004653931} +{"content": "How Mars Lost Its Water, a Crucial Component of Life.\nAccording to a study, Mars’ liquid water, which is essential for life, may have evaporated due to its small size.\nAccording to Washington University researchers, the Red Planet’s size may be the main reason it lost liquid water and looks so different from Earth’s “blue marble” despite being so close.\nThe proposal, which was presented in an article published in the journal PNAS, is one of several proposed to explain why liquid water no longer flows across Mars’ surface.\nIn a news release from Washington University, co-author Kun Wang, assistant professor of Earth and planetary sciences, remarked, “Mars’ fate was decided from the beginning.”\nWe’ve known that water once flowed freely on Mars since at least 1971, when the Mariner 9 Mars probe took photographs of dried river beds on the Red Planet’s surface. More dry lake beds and river basins have been discovered since then by subsequent trips.\nAccording to scientists at the California Institute of Technology (Caltech), there was enough water on Mars four billion years ago to cover the entire planet in a 1,500-meter-deep ocean (4,921 feet).\nThe fact that water only appears to exist on Mars as ice at high elevations raises the question of what happened to the planet’s liquid water.\nWhat Happened to Mars’ Water?\nWang and the Washington University team examined a stable form of potassium, or isotope, in 20 proven Martian meteorites to come to the conclusion that Mars lost its water due to its small size. Potassium is a useful indicator of volatiles, which are quickly vaporized substances such as water.\nThe researchers had previously used the same technology to study the formation of the moon. Mars clung to its volatiles for much longer than smaller worlds like the moon and the asteroid 4-Vesta, according to the researchers.\n“With a mass greater than Mars, there is likely a limitation on the size needs of rocky planets to retain enough water to support habitability and plate tectonics,” Wang added.\nThis implies that the larger a planet or other space object is, the longer it is likely to hang on to its volatiles, such as water, which is a necessary component of life.\nThis is not the case. This is a condensed version of the information.", "pred_label": "__label__POS", "pred_score_pos": 0.7093757390975952} +{"content": "By Cassandra Banks- Snapshot Parents of both genders can appear to treat children as objects to be passed between them. They need to shift their focus to what the child needs Law makers and the courts are trying to provide children with the opportunity for a meaningful relationship with both parents\nIt was debated that the 2006 amendments to the\nFamily Law Act 1975 were intended to reflect a “new attitude” towards post-separation parenting. The Attorney-General’s Department at the time labelled it “the most significant change to family law in over 30 years”. The question remains, did the amendments provide an equal playing field or did they, as is often suggested by men’s support organisations, give fathers unrealistic expectations that equal shared parental responsibility equated with equal shared time? Was this a promotion of a fundamental feminist agenda or clever political manipulation?\nThis is not easily answered in a short article. However, the short answer could be as is stated in the\nAustralian Master Family Law Guide (6th Edition, CCH) that the Act “focuses on the importance of both parents playing an active role in the lives of their children after separation”. Is the Family Law Actunconsciously promoting a fundamental feminist agenda? I would answer no.", "pred_label": "__label__POS", "pred_score_pos": 0.7619965076446533} +{"content": "Young People's Experience of Participation When Exiting out of Care. Abstract\nThe aim of this paper is to focus on young people's experiences of participation during the process of transition from placements in out-of-home care independent life. 65 young care leavers were interviewed, 14 boys and 51 girls between 18 and 26 years old. Results show that those who were invited to participate in the planning of their care leaving experienced a more positive and successful transition from care to adulthood. When administrative regulations guided the care leaving process, young people felt excluded and out of control, and their transition became a more negative experience.", "pred_label": "__label__POS", "pred_score_pos": 0.6171334981918335} +{"content": "We all want to feel cared for and valued by the significant people in our life. When students feel that you value and care for them as individuals, they are more willing to comply with our requests. Developing positive teacher-student relations is also one of the most effective steps we can take to establish a positive climate in the classroom.\nRead more: Be Authentic. Take Interest. Respect.", "pred_label": "__label__POS", "pred_score_pos": 0.8032369613647461} +{"content": "CONCORD members gathered in Prague this November to explore possibilities of a cultural shift in NGOs sector. As Civil Society Organisations (CSOs) are challenged, criminalised and losing support from their governments and the citizens, the aim of Learning & Exchange Forum 2018 was to explore how CSOs can change their culture to sharpen their values and remain relevant.\nThe Cotonou Partnership Agreement is coming to an end in 2020. To ensure a fair ground leading to a “partnership of equals”, CONCORD has developed a list of recommendations, serving as a contribution from civil society to the ongoing EU-ACP negotiations to ensure mutually beneficial priorities.\nThe European Commission has officially launched negotiations with the African, Caribbean and Pacific countries (ACP) on a new partnership agreement to succeed the Cotonou Agreement. This represents an opportunity to build people-centered cooperation as equal partners but, there is concern about the narrative of Africa being portrayed only as Europe’s trade and economic partner.\nThe Cotonou Partnership Agreement, the EU partnership with ACP countries (African – Caribbean and Pacific), will expire in 2020 and the official negotiations will start in August 2018. Read CONCORD’s recommendations to put “People and Planet first” in the future EU-ACP agreement.\nFor two days, on December 6th and 7th, CONCORD and the FIP-IFP organised a seminar on the post-Cotonou process. These 2 days closed with a multi-stakeholders debate, titled “Stand up for a better future for all”. What came out of this process? What have we learned? What are the next steps? Read the joint statement and discover much more in this blogpost.", "pred_label": "__label__POS", "pred_score_pos": 0.5096138715744019} +{"content": "Just a reminder the Financial Accounting Standards Board (FASB) previously issued Lease Accounting Standard as codified in Accounting Standard Codification (ASC) No. 842, is fast approaching for nonpublic entities maintaining GAAP financial statements.\nEffective January 1, 2022, ASC 842 fundamentally changes the accounting for lessees with operating leases having a term greater than 12-months. The accounting standard will require these leases to be recorded on the lessee’s balance sheet with a right-to-use asset and a lease liability which may substantially change balance sheet measurements, key ratios and have the potential to trigger loan covenants in place in 2022 when this standard becomes effective.\nThe standard offers two transitional methods with practical expedients and will require expanded qualitative and quantitative disclosures in your financial statements.\nBecause this standard is requiring more time by company finance personnel to implement than the industry anticipated, DHA will be offering accounting support services for lease accounting beginning in October 2021 which will include the use of best-in-class cloud-based software to accelerate the implementation and support needed by management with the quantitative and qualitative compliance burdens.\nLook for our communications on this lease accounting support coming in September and contact us early to reserve a spot for your support necessary to effectively get this standard implemented by January 1, 2022 for your company.\nWritten By Brad Reich, DHA CPAs", "pred_label": "__label__POS", "pred_score_pos": 0.6233970522880554} +{"content": "ASCI’s guidelines fall flat when put under the scanner by industry experts because of the lack of clarity and industry unwillingness.\nThough the stated claim of ASCI’s influencer guidelines is to bring transparency and accountability in the fast-growing influencer market in India, responses from industry players concerning the feasibility of implementing these guidelines have been mixed, with some claiming it has a significant impact. In contrast, others say it is business as usual.\nCampaign India reports Urban Company’s marketing director Tarun Menon saying, “The brand always believed in a transparent approach when it came to influencer activity.” However, Money Control’s simple review of Instagram profiles of a few major influencers argues that this is not the case for most of the brand-influencers collaborations.\nThis may be due to a lack of clarity regarding the guidelines. For instance, Money Control reports that influencer Dolly Singh, in over a minute-long video regarding skincare products by Olay, has mentioned #ad in the description but not in the video. Technically, this amounts to the violation of the disclosure clause under the guidelines.\nOn the other hand, there is also an unwillingness to comply from brands and influencers’ side, as these disclosures may lower the engagement rate for influencer ad campaigns.\nWith the non-binding nature of these guidelines, there is a limit to which ASCI can push them on its own. Apart from monitoring and reporting, ASCI will proactively have to look for ways to gain support from the industry players.", "pred_label": "__label__POS", "pred_score_pos": 0.5799214243888855} +{"content": "Topic\nSocial media has allowed news to be shared and consumed more widely than ever. This has had an overall positive effect on political, social and economic life. To what extent do you agree with this statement? Support your argument with relevant examples.\nMain requirement\n1. 2500 words +/-10%\n2. Reference style: APA\n3. DDL:2021.7.18 Sunday noon\nIntroduction 200-300 words\nExplain the words marked in red above, state the context in which they appear and the possible effects. In this section, you can introduce your definitions of key terms. At the end of the introduction, you should inform the reader to what extent you agree with the thesis of the title, and give a brief explanation. Optional: In this section you can tell the reader how your text is distributed.\nMain body :approximately: 2000words\nYou can use three or four subheadings to help you start a critical discussion that supports the arguments you’ve made in the introduction.\nIt should be noted that you should use the standard P.E.E format for each paragraph, including points, examples, and Explain. At the same time, you can’t just support a point, you need to critically argue, consider the pros and cons of the academic community, and finally assess that the point is correct and can support your text.\nConclusion 200 words\nSummarize the results of your discussion and inform the reader. Restate your attitude on the whole subject.", "pred_label": "__label__POS", "pred_score_pos": 0.7649515271186829} +{"content": "As the opioid epidemic continues to sweep the nation, lawmakers are becoming more conscious of the risks of drugs and criminalizing drug activity. While it is possible to face drug charges after overdosing in Tennessee, there is a Good Samaritan law that may provide some relief for those seeking medical attention to help a person who is overdosing or even to the person who is going through the overdose process. However, it is important to understand the nuances of this law to know when it may apply and the protections it provides.\nHow the law works\nThe law states that any person who seeks medical assistance in good faith for a person who is currently overdosing shall not be charged, arrested or prosecuted for a drug violation if the evidence for such criminal proceedings would be based on seeking and receiving such medical assistance. This law applies to bystanders witnessing such an overdose or the person who is experiencing the overdose. However, for the person experiencing the overdose, the immunity from prosecution and criminal charges only applies to the person's first such overdose.\nDrug overdose defined\nThe law protects the individuals if the person is actually overdosing or is believed to be overdosing. A drug overdose is defined as an acute condition believed to be linked to the use, inhalation, ingestion or injection of a controlled substance that may involve some of the following symptoms:\nComa Decreased level of consciousness Extreme physical illness Mania Respiratory depression Seeking medical assistance\nThe immunity from prosecution only applies if the person experiencing the overdose or a bystander calls 911 for assistance, contacts a poison control center or law enforcement or provides care while awaiting assistance.\nSpecial considerations\nAs explained above, for the person experiencing the drug overdose, immunity under this law is only available for the first time that this situation arises. Law enforcement is not prohibited from prosecuting drug charges if they have evidence not related to the seeking of medical assistance. If the defendant was committing another crime not related to the overdose, law enforcement may still be able to arrest him or her and continue with the prosecution for other crimes.\nEven if the immunity law does not apply, seeking medical assistance may be used as a mitigating factor in the criminal prosecution.\nSpeak with a Murfreesboro Criminal Defense Lawyer\nThe experienced Murfreesboro criminal defense team at Taylor Law Group is ready to help. We help our clients defend against all types of criminal charges, so please do not wait to contact us online or call 615-890-1982 for a consultation.", "pred_label": "__label__POS", "pred_score_pos": 0.7622836828231812} +{"content": "For the modern enterprise, HR processes are increasingly complex and fraught with potential waste and error. Cycles that should take only two days may take 10 days or more. Perhaps an offer letter has been generated, but approval is repeatedly delayed. This leads to missed opportunities, and each process reboot erodes the ability to recruit...", "pred_label": "__label__POS", "pred_score_pos": 0.6188434362411499} +{"content": "In a new study, a team of researchers from Japan propose and validate an analytical model for studying cheetah galloping by comparing its predictions with cheetah data. While improving upon the current understanding of cheetah’s locomotion, their findings pave the way for designing legged robots!\n“All animal running constitutes a flight phase and a stance phase, with different dynamics governing each phase,” explains Dr. Tomoya Kamimura from Nagoya Institute of Technology, Japan, who specializes in intelligent mechanics and locomotion.\nDuring the flight phase, all feet are in the air and the center of mass (COM) of the whole body exhibits ballistic motion. Conversely, during the stance phase, the body receives ground reaction forces through the feet.\n“Due to such complex and hybrid dynamics, observations can only get us so far in unravelling the mechanisms underlying the running dynamics of animals,” Dr. Kamimura says.\nConsequently, researchers have turned to computer modelling to gain a better dynamic perspective of the animal gait and spine movement during running and have had remarkable success using fairly simple models. However, few studies so far have explored the types of flight and spine motion during galloping (as seen in a cheetah).\nAgainst this backdrop, Dr. Kamimura and his colleagues from Japan have now addressed this issue in a recent study published in Scientific Reports, using a simple model emulating vertical and spine movement.\nThe team, in their study, employed a two-dimensional model comprising two rigid bodies and two massless bars (representing the cheetah’s legs), with the bodies connected by a joint to replicate the bending motion of the spine and a torsional spring. Additionally, they assumed an anterior-posterior symmetry, assigning identical dynamical roles to the fore and hind legs.\nBy solving the simplified equations of motion governing this model, the team obtained six possible periodic solutions, with two of them resembling two different flight types\n(like cheetah galloping) and four, only one flight type (unlike cheetah galloping), based on the criteria related to the ground reaction forces provided by the solutions themselves. Researchers then verified these criteria with measured cheetah data, revealing that cheetah galloping in the real world indeed satisfied the criterion for two flight types through spine bending.\nAdditionally, the periodic solutions also revealed that horse galloping only involves gathered flight due to restricted spine motion, suggesting that the additional extended flight in\ncheetahs combined with spine bending allowed them to achieve such great speeds!\n“While the mechanism underlying this difference in flight types between animal species still remains unclear, our findings extend the understanding of the dynamic mechanisms underlying high-speed locomotion in cheetahs. Furthermore, they can be applied to the mechanical and control design of legged robots in the future,” speculates an optimistic Dr Kamimura.", "pred_label": "__label__POS", "pred_score_pos": 0.9254174828529358} +{"content": "Our Terms of Service prohibit misinformation related to vaccines. Since implementing our anti-vaccine policy in 2019, we have removed hundreds of fundraisers from our platform that violated this term by attempting to promote misinformation related to vaccines that have been approved by regulatory bodies.\nWhen it comes to our policy, we are committed to legal and regulatory compliance and are guided by scientific evidence from health authorities and governing bodies. The World Health Organization announced the list of vaccines against Covid-19 that meet necessary criteria for safety and efficacy in June 2021, and the U.S. Food & Drug Administration (FDA) approved the first COVID-19 vaccine in August 2021. GoFundMe’s policy reflects this guidance.\nThroughout the ongoing and constantly evolving COVID-19 crisis, we have seen several issues related to vaccines and other mandates begin to manifest on our platform. To maintain the safety of our organizer and donor community, our Trust & Safety team have implemented the following proactive measures:\nAdded Resource labels to educate our users on fundraisers related to COVID-19 Identified organizations and individuals off the platform that have spread harmful misinformation and took proactive measures to prevent them from ever getting onto our platform Monitored for organizations and individuals that are on our platform for other fundraising purposes, but that are affiliated with the spreading of misinformation off platform Expanded our proactive monitoring measures to include emerging, misleading claims about medical products that prevent, treat, mitigate, diagnose or cure COVID-19\nIf the fundraiser violates our Anti-Vaccine policy or Terms of Service, the fundraiser and/or the account associated with the fundraiser, will be removed.\nHealth care needs: Medical expenses related to COVID-19 and vaccine-related injuries Funeral/Memorial for individuals passed from COVID-19 Nonprofit organizations expanding vaccine accessibility Mask + Vaccine mandates: Legal fees to legally challenge a mandate Dispute/pay fines if a fine was already issued\nThe constantly changing public discourse throughout this pandemic creates a unique and challenging situation for many platforms. There is not one answer or catch all, but we are remaining agile and committed to evolving our processes to identify and stop as many people as possible from spreading harmful misinformation.\nFor additional resources and guidance on vaccines, including their safety and efficacy, please visit the following authorities:", "pred_label": "__label__POS", "pred_score_pos": 0.8421962857246399} +{"content": "At Santa Rosa Gardens, we ship plants in pots rather than bareroot. By minimizing plant stress, and transplant shock, plants can adapt and grow more quickly and thrive in your garden, so you can grow with confidence.\nOur young plants are at the right stage to transplant with minimal stress, and when planted in the right place, they can take off with youthful vigor. Young plants with healthy roots, like the ones we ship, often result in better growth over time compared to larger nursery pots.\nFirst, we wrap each plant in a protective sleeve. Then they are secured and locked in place within the box, using our special designed cardboard insert. Every part of our packaging is recyclable.", "pred_label": "__label__POS", "pred_score_pos": 0.9943245649337769} +{"content": "Youth Leadership and Voice refers to the ideas, knowledge, opinions and access to the platforms that are necessary for youth to exercise their right to speak out around issues and policies that directly or indirectly affect them.\nResources December 12, 2016\nThese are the stories of several first-generation college students and graduates, and this video explores their challenges, sources of support, and recommendat…\nThis webinar featured the voices of young people and highlighted programs that are effectively leveraging youth voice and advocacy to promote policy change.\nNovember 14, 2016\nCarinne Deeds highlights shared education goals for 2017 and beyond.", "pred_label": "__label__POS", "pred_score_pos": 0.95071941614151} +{"content": "The Monetary Policy Committee (MPC) will hold its next meeting on Monday, January 22, 2018, the Central Bank of Kenya (CBK) has said.\nDuring its last meeting held two weeks ago, the MPC once more retained the base lending rate at 10.0%, saying inflationary pressures in the economy were muted, and inflation was expected to continue to decline in the short term.\nAccording to the committee, month-on-month overall inflation fell to 5.7% in October 2017 from 7.1% in September 2017, thereby remaining within the Government target range.\nThis decline was largely due to lower food prices, particularly for cabbages and Irish potatoes. The decrease in food prices offset the increases in fuel and electricity prices in October.\nCBK Governor Dr Patrick Njoroge, who chairs the Committee, non-food-non-fuel (NFNF) inflation remained below 5%, demonstrating that demand pressures are muted. Despite an increase in international oil prices which has exerted upward pressure on fuel prices, improved weather conditions and the extension of the maize subsidy are expected to continue supporting a further lowering in food prices and a decline in overall inflation in the near term, he added.\nDuring the next meeting, it is expected that MPC might give direction on plans to review the interest rate caps law following the negative performance of the banking sector in 2017, which was partly attributed to the law that was effected in September 2016.\nAfter the last meeting on November 23, Njoroge said the MPC continues to monitor the impact of the interest rate caps on the effective transmission of monetary policy.\nThe Kenya Bankers Association and individual banks have been pushing for a revision of the law that caps interest rates at 4% above the base lending rate, also known as the Central Bank Rate (CBR). It has stood at 10% since late last year.\n“The CBK will continue to closely monitor developments in the global and domestic economy, and stands ready to take additional measures as necessary,” he said.", "pred_label": "__label__POS", "pred_score_pos": 0.9552510976791382} +{"content": "Transposable elements are not reactivated in natural hybrids of the yeast Saccharomyces paradoxus, but their accumulation is genotype-specific and is not predicted by the evolutionary divergence between a hybrid's parents.\nIn addition to its academic merits, characterizing the genetic determinants of male (in)fertility and identifying clinically actionable genetic variants can lead to improved diagnosis or even treatment of such conditions.", "pred_label": "__label__POS", "pred_score_pos": 0.6000901460647583} +{"content": "Market Snapshot\nThe golf cart market revenue is likely to touch\nUS$ 2.9 Bn by 2021, according to Fact. MR. The overall golf cart market is expected to reach US$ 5.4 Bn by 2031, expanding nearly 2x.\nDemand for electric golf carts is expected to be influenced by the 5 market players, holding\n48% of the golf cart market in 2021. Rising demand for fast, electric, and technologically advanced golf carts with eco-friendly components will propel the industry at a CAGR exceeding 6% through 2031. Key Points Covered in Golf Cart Industry Survey Market Estimates and Forecasts (2016-2031) Key Drivers and Restraints Shaping Market Growth Segment-wise, Country-wise, and Region-wise Analysis Competition Mapping and Benchmarking Brand Share and Market Share Analysis Key Product Innovations and Regulatory Climate COVID-19 Impact on Golf Carts and How to Navigate Recommendation on Key Winning Strategies\nKnow More Details About the Report\nGolf Carts Revenue Analysis 2016-2020 Vs Future Outlook 2021-2031\nAccording to Fact.MR- a market research and competitive intelligence provider- global market for golf carts has grown at a CAGR of\n3.6% from 2016-2020. Extensive utilization for transportation purposes including personal use, golf courses and industry use has accelerated demand in the historical period.\nEnd users are exhibiting preference for custom-built golf carts with additional add-ons to suit user requirements. Using a golf cart or LSVs for short trips helps conserve fuel and achieve transportation economy, another key reason for their uptake.\nThe combination of these factors leads to ideal conditions for the expansion of golf carts demand around the world. As per the market study, overall demand is expected to surge at a CAGR of\n6.3% from 2021 to 2031 to reach US$ 5.3 Bn. How is the Scramble for Fuel Economy Spurring Golf Carts Demand?\nThe growing need for golf carts in residential areas, hotels, airports, university campuses, and railway stations has contributed to the increasing demand for golf carts. Since they are electric powered, golf carts emit low noise, offer greater safety, and reduce the likelihood of emissions.\nAdditionally, rapid industrialization has prompted the development of new technological golf carts for industrial uses. Advancements and technological innovations such as the reduced need for components replacement, faster recharge cycles, and high durability are bolstering demand for golf carts in the global market.\nAvail customized purchase options for your needs\nHow are Low-Speed Vehicle Tests Spurring R&D in Golf Carts?\nA lot of research and development on golf carts is conducted across several regions. One example is the deployment in the Cape Fear region. From fairways to roadways, golf carts are becoming mainstream, offering people a convenient option to travel around town.\nTests are conducted on low-speed vehicles to see if they can share the road with faster vehicles and travel along state-maintained roads. According to various studies, the vehicles have been legally allowed on state-run roads with a 35 mph speed limit. In the region, these vehicles are governed by the same rules as motor vehicles. Hence, manufacturers are accelerating R&D to augment supply.\nCountry-wise Insights What is the Demand Outlook for Golf Carts in the U.S.?\nRising disposable incomes and the increased popularity of golf has spurred sales of golf carts in the U.S. Golf carts equipped with batteries and solar power are contributing to market growth, which is resulting in a spike in demand for golf carts.\nThe increasing number of golf courses in the country is expected to increase the demand for the golf carts market. As per Fact.MR’s projections, the U.S golf carts industry reached\nUS$ 1 Bn as of 2020, expected to grow at a CAGR of 6% until 2031. How is the Asian Region Broadening Prospects for Golf Cart Sales?\nThe Asian region has experienced urbanization that is resulting in urban lifestyles of improved citizens that are creating a need for luxurious lifestyles. India, China, and Japan are considered high potential markets for golf cart sales in Asia.\nThe need for eco-friendly vehicles in this region is one of the biggest factors influencing electric device sales. With the help of technological innovations in the field of battery management, golf cart manufacturers can improve vehicle range and reduce charging cycles.\nThe use of golf carts in this region can be attributed to the stringent rules applied by the government on emissions of pollutants in the atmosphere and the rising demand for electric vehicles will surge the market for golf carts. The region is poised to hold around\n60% revenue share.\nAn Adaptive Approach to Modern-day Research Needs\nCategory-wise Insights How is Demand for Push-Pull Carts Expected to Grow?\nA growing awareness of the health, wealth, and fitness benefits of walking is propelling the demand for push-pull carts among golfers. A CAGR of\n5% is projected for this segment until 2031.\nIn golf, push-pull carts occupy a unique place in the market. Foldable and motorized carts are in high demand due to their ease of use and reduction of physical exertion from pulling a lug or moving them around the golf course.\nWhy are Powered Golf Carts Acquiring Traction?\nAccording to Fact.MR, demand for powered golf carts is anticipated to surge at a CAGR of over\n5% to reach a substantial valuation by 2031. Heightening demand for automation in industrial and sports settings is primarily accelerating sales for many years.\nDemand for electric-powered golf carts is expected to gain significant traction, as end users strive to incorporate more environmentally conducive transportation alternatives.\nCompetitive Landscape\nMajor players with a prominent share in the market are focusing on expanding their customer base.\nFor instance, Club Car has designed Disney Robot Golf Carts, introduced at Walt Disney World Resort’s Orlando golf courses. Using Bluetooth and GPS technology, the robotic TempoWalkcarts transport clubs around Disney's golf courses at Palm, Magnolia, and Oak Trail. Likewise, Cricket Mini Golf Carts designed a fully suspended electric mini golf cart that is lightweight, portable, easy to own, four-seater, and fun to drive. The cart is eco-friendly, collapsible, and can fit in a motorhome basement.\nHave a report related query? Speak to us directly\nReport Scope\nAttribute\nDetails\nForecast Period\n2021-2031\nHistorical Data Available for\n2016-2020\nMarket Analysis\nUS$ Mn for Value & ‘000 Units for Volume\nKey Regions Covered\nKey Countries Covered\nKey Market Segments Covered\nKey Companies Profiled\nPricing\nAvailable upon Request\nKey Segments Covered\nProduct Push-Pull Golf Carts Gasoline Golf Carts Electric Golf Carts Solar Powered Golf Carts\nOperation Manual Golf Carts Powered Golf Carts\nApplication Golf Carts for Golf Courses Golf Carts for Personal Use Golf Carts for Industry Use Golf Carts for Other Applications\nOwnership Rented Golf Carts Fully Owned Golf Carts Golf Cart Market- Scope of Report\nA recent study by Fact.MR on the golf cart market offers a 10-year forecast for 2021 to 2031. The study analyzes crucial trends that are currently determining the growth of the market. This report explicates on vital dynamics, such as the drivers, restraints, and opportunities for key market players along with key stakeholders as well as emerging players associated with offering golf carts.\nThe study also provides the dynamics responsible for influencing the future status of the golf cart market over the forecast period. A detailed assessment of value chain analysis, business execution, and supply chain analysis across regional markets has been covered in the report.\nA list of prominent companies operating in the golf cart market, along with their product portfolios, enhances the reliability of this comprehensive research study.\nReport Summary\nThe study offers comprehensive analysis on diverse features, including production capacities, demand, product developments, revenue generation, and sales of golf carts across the globe.\nA comprehensive estimate on the market has been provided through an optimistic as well as a conservative scenario, taking into account the sales of golf carts during the forecast period. Price point comparison by region with global average price is also considered in the study.\nKey Questions Answered in Report Which are the most lucrative golf cart markets? Which factors will impact the growth of golf carts? How will changing trends impact the strategies of market players? How can market players capture the low-hanging opportunities across regions? Which companies are leading the golf cart industry? What are the winning strategies of stakeholders in the market? Analysis on Market Size Evaluation\nThe market has been analyzed for each segment in terms of volume (‘000 Units) and value (US$ Mn).\nEstimates at global and regional levels for golf carts are available in terms of “US$ Mn” for value and in “‘000 Units” for volume. A Y-o-Y growth contrast on prominent market segments, along with market attractiveness evaluation, has been incorporated in the report. Furthermore, absolute dollar opportunity analysis of all the segments adds prominence to the report. Absolute dollar opportunity plays a crucial role in assessing the level of opportunity that a manufacturer/distributor can look to achieve, along with identifying potential resources, considering the sales and distribution perspective in the global golf cart market.\nInspected Assessment on Regional Segments\nKey sections have been elaborated in the report, which have helped deliver projections on regional markets. These chapters include regional macros (political, economic, and business environment outlook), which are expected to have a momentous influence on the growth of the golf cart market during the forecast period.\nCountry-specific valuation on demand for golf carts has been offered for each region, along with market scope estimates and forecasts, price index, and impact analysis of the dynamics of prominence in regions and countries. For all regional markets, Y-o-Y growth estimates have also been incorporated in the report.\nDetailed breakup in terms of value & volume for emerging countries has also been included in the report.\nIn-depth Analysis on Competition Analysis\nThe report sheds light on leading manufacturers of golf carts, along with their detailed profiles. Essential and up-to-date data related to market performers who are principally engaged in offering golf cart has been brought with the help of a detailed dashboard view. Market share analysis and comparison of prominent players provided in the report permits report readers to take preemptive steps in advancing their businesses.\nCompany profiles have been included in the report, which include essentials such as product portfolios and key strategies, along with all-inclusive SWOT analysis on each player. Company presence is mapped and presented through a matrix for all the prominent players, thus providing readers with actionable insights, which helps in thoughtfully presenting the market status, and predicting the competition level in the golf cart domain.\nResearch Methodology\nIn Fact.MR’s study, a unique research methodology is utilized to conduct extensive research on the growth of the golf cart industry, and reach conclusions on the future growth parameters. This research methodology is a combination of primary and secondary research, which helps analysts ensure the accuracy and reliability of the drawn conclusions.\nSecondary resources referred to by analysts during the preparation of the market study include statistics from governmental organizations, trade journals, white papers, and internal and external proprietary databases. Analysts have interviewed senior managers, product portfolio managers, CEOs, VPs, marketing/product managers, and market intelligence managers, all of whom have contributed to the development of the research report as a primary resource.\n- FAQs -\nBy 2021, sales of golf carts are likely to reach US$ 2.9 Bn in value, as per Fact.MR’s recent study\nThe overall golf cart market is expected to reach US$ 5.4 Bn by 2031, growing at a CAGR of 6.3% for 2021-2031\nAccording to Fact.MR, between 2016 and 2020, golf carts sales expanded at a CAGR of 3.6%\nAdoption of new technologies and rising popularity of electric vehicles is trending in the golf cart market\nIncreasing need to replace fuel powered vehicles with electric vehicles is driving demand for golf carts\nThe top players such as Club Car LLC, E-Z Go, Yamaha Golf Car Company, Columbia ParCar Corp, and Hitachi Co. Ltd., hold 48% of the overall market share\nU.S, China, India, Japan and South Korea are expected to influence future golf carts demand\nThe U.S golf carts market is expected to expand at a CAGR of 6% over the forecast period\nThe market for Europe is expected to expand at a CAGR of 6.1% over the forecast period\nThe Asian market for golf carts is expected to generate 60% of global revenue until 2031\nNeed an Exclusive Report for your Unique Requirement? - Related Reports - Talk Show: The Rise of Intelligent Packaging Personalized, Connected and Sustainable - Our Clients - - Evaluate How Fact.MR's Report Can Help. - Is the market research conducted by Fact.MR?\nYes, the report has been compiled by expert analysts of Fact.MR, through a combination of primary and secondary research. To know more about how the research was conducted, you can speak to a research analyst.\nWhat research methodology is followed by Fact.MR?\nFact.MR follows a methodology that encompasses the demand-side assessment of the market, and triangulates the same through a supply-side analysis. This methodology is based on the use of standard market structure, methods, and definitions.\nWhat are the sources of secondary research?\nFact.MR conducts extensive secondary research through proprietary databases, paid databases, and information available in the public domain. We refer to industry associations, company press releases, annual reports, investor presentations, and research papers. More information about desk research is available upon request.\nWho are the respondents for primary research?\nFact.MR speaks to stakeholders across the spectrum, including C-level executives, distributors, product manufacturers, and industry experts. For a full list of primary respondents, please reach out to us.\nIs a sample of this report available for evaluation?\nYes, you can request a sample, and it will be sent to you through an email.", "pred_label": "__label__POS", "pred_score_pos": 0.514684796333313} +{"content": "The clean energy sector is playing a leading role in providing the solutions to meet the net zero by 2050 target. In the run up to the 26th UN Climate Change Conference of the Parties (COP26) in Glasgow this November, we want to showcase the leading efforts of our vibrant sector.\n#FacesoftheEnergyTransition is a digital campaign run by all the UK energy trade associations, supported by COP26 and Race To Zero digital channels, designed to celebrate the inspiring individuals and pioneering projects working to achieve the clean energy transition and tackle the climate crisis internationally.\nWe have produced a series of videos celebrating those individuals – click through them below to hear inspiring stories from voices across the sector.", "pred_label": "__label__POS", "pred_score_pos": 0.9717232584953308} +{"content": "When investigating an industrial incident, one piece of information I always ask for is the relevant P&ID’s for the process. P&ID stands for Piping and Instrumentation Diagram and is defined as “A schematic diagram of the relationship between instruments, controllers, piping, and system equipment.” The information from the P&ID’s covering the vessel or vessels involved in an incident can be very useful.", "pred_label": "__label__POS", "pred_score_pos": 0.5418068170547485} +{"content": "Ether (ETH) hit higher lows over the course of 2021, and the current trend suggests that $ 1,800 could be the low for April. Even traders and investors who don’t rely on tech specs have become optimists after Visa launched a pilot to process USD Coin (USDC) transactions over the Ethereum network.\nGiven that the price of Ether looks like it is ready to hit new annual highs, there are some investment opportunities on the table. Buying and holding is an excellent strategy and leveraged long up to 2x. The problem is on the downside, as a 20% move in futures contracts would result in a 40% loss. Not to mention, there isn’t a lot of room for additional leverage as it requires a substantial advance payment.\nOption strategies, on the other hand, offer excellent opportunities for traders who have a set goal. For those who expect a moderate price increase of 15% in 30 days, the “Iron Condor” strategy, for example, offers 12% profit with minimal upfront requirements. This strategy also limits the disadvantage to 10% regardless of how the asset performs.\nThis bullish strategy is to buy 10 ethers worth $ 1,600 put options while selling the same amount of $ 2,240 calls. To complete the trade, the buyer sells put options worth 7.5 ethers valued at $ 2,080 and settles them by purchasing 8 ether contracts valued at $ 2,880.\nIn contrast to perpetual futures (inverse swaps), options have a fixed expiry date, so that the expected result must occur during the defined period.\nThe Ether (ETH) calendar option below refers to the end of April 30th. However, this strategy can also be applied to Bitcoin (BTC) or applied to any other time period.\nDerivatives exchanges value these contracts in ether, ie the displayed profits and losses are calculated in ether fractions on the expiry date.\nGiven that Ether is currently trading at $ 1,810, any result between $ 1,790 and $ 2,545 (up 40.6%) will result in a net profit. For example, a price increase of 15% to $ 2,080 results in a net profit of 1.2 ETH, or $ 2,500.\nThe maximum loss of this strategy is 1.04 ETH. This will happen if the price is below $ 1,600 (minus 12%) or above $ 2,545 on April 30th.\nThe appeal of the Iron Condor strategy is the potential gain of 1.2 ETH, while losses are limited to under $ 1,600 upon expiry.\nOverall, this conservative strategy gives a much better risk / return rate than trading leveraged futures due to the limited disadvantage. The upfront cost (deposit) is 1.04 ETH and this also reflects the maximum potential loss.\nThe views and opinions expressed here are solely those of author and do not necessarily reflect the views of Cointelegraph. Every investment and trading step is associated with risks. You should do your own research when making a decision.", "pred_label": "__label__POS", "pred_score_pos": 0.6082586050033569} +{"content": "The value-depressing ripple effect that foreclosures can have on homes also relates to apartment buildings in New York City. A study by the Citizens Housing & Planning Council and Enterprise organization showed that buildings\nwithin 250 feet of ones that were in foreclosure saw a 14% increase in Class C housing code violations. As a neighborhood's value becomes more imperiled due to foreclosed properties, landlords are suspected of making fewer repairs to nearby buildings and allowing more housing code violations. [WSJ]\nFiled under:", "pred_label": "__label__POS", "pred_score_pos": 0.8614040613174438} +{"content": "Mindfulness\nMindfulness can have a positive effect on symptoms like irritability, depression, and anxiety in middle-aged menopausal women. The goal during mindful moments is not to empty the mind but to become an observer of the mind’s activity while being kind to oneself. The second step is to create a pause. Take a deep breath and observe one’s own space, thoughts, and emotions non-judgmentally. The resulting calm helps lower stress.\nTreatment Type: Lifestyle Changes MMM Reviews:\nThis lifestyle change has not been reviewed by the Menopause Made Modern team.", "pred_label": "__label__POS", "pred_score_pos": 0.5634970664978027} +{"content": "The optimal diet involves eating mostly 'real', whole, nutrient-dense foods and avoiding food 'products' that include processed, addictive, inflammatory food like products high in flours, sugars, trans-fats, salt and toxic additives.\nBelow are some sample recipes to try, most of which are incorporated into e-recipe books provided during a NuU healing programme.", "pred_label": "__label__POS", "pred_score_pos": 0.9607268571853638} +{"content": "Our women’s health physiotherapy program focuses on pelvic floor function and dysfunction in women with range of pelvic floor disorders. We are currently exploring:\nPelvic pain: Women with endometriosis and persistent pelvic pain. We are exploring pelvic floor muscle properties, specifically muscle tenderness and muscle tone, as well as symptoms of bladder, bowel and sexual dysfunction and psychosocial distress, in women pre- and post-laparoscopy for pelvic pain. Women with provoked vestibulodynia, and ultrasound elastography to explore pelvic floor muscle stiffness. Pelvic floor disorders, including bladder and bowel incontinence and pelvic organ prolapse, in women who: Engage in regular exercise, including elite female athletes Are diagnosed with and have undergone treatment for gynaecological cancer Have undergone treatment for breast cancer The feasibility, clinical and cost effectiveness effectiveness of telehealth-delivered pelvic floor muscle training to treat urinary incontinence in women following treatment for gyneacological or breast cancer. Researchers Graduate Researchers\nJodie Dakic\nRobyn Brennen\nUdari Colombage\nRachel Nelligan", "pred_label": "__label__POS", "pred_score_pos": 0.6816112995147705} +{"content": "We screen natural products for antimicrobial, antiviral and anticancer activity, immunomodulatory effects, as inhibitors of cell adhesion and antioxidants. High-resolution MRI-tomography with 7T magnet (PharmaScan 70/16US, Bruker) allows us to search in situ for compounds with anticancer, anti-stroke and anti ischemia activity, inhibitors of angiogenesis and hepatoprotective substances.\nAuthors: Aminin D.L., Anisimov M.M., Prokof’eva N.G., Agafonova I.G., Likhatskaya G.N., Stonik V.A.\nThis work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License", "pred_label": "__label__POS", "pred_score_pos": 0.8433786034584045} +{"content": "To ask Her Majesty's Government what assessment they have made of the knowledge and understanding school Designated Safeguarding Leads (DSLs) have of child sexual abuse; and what training DSLs receive to help them to respond appropriately.\nAnswered on\n8 July 2021\nSchools and colleges must have regard to the statutory safeguarding guidance ‘Keeping children safe in education’ (KCSIE). This guidance sets out the role of the designated safeguarding lead, and highlights that they should undergo training to provide them with the knowledge and skills required to fulfil the role. Designated safeguarding leads (DSLs) should have a good understanding of their own role, and the processes, procedures, and responsibilities of other agencies.\nThe department keeps the KCSIE guidance under review, updating and strengthening it as required (usually on an annual basis), to ensure all schools and colleges have the guidance to meet their statutory duties to safeguard children. As part of this, we also carry out regular public consultations, with the most recent closing on 4 March 2021. In total, 90% of respondents agreed that Part five of the draft guidance provides schools and colleges with the right level of information to support them to manage reports of child-on-child sexual violence and sexual harassment effectively. Of the 7% who said it was not enough, the information which they would like to see included is already within the additional advice document, entitled ‘Sexual Violence and Sexual Harassment between children in schools and colleges’ (SVSH). KCSIE is supplemented with SVSH, which provides detailed advice about all types of child sexual abuse, including peer-on-peer abuse, the focus of the recent Ofsted review.\nThe guidance helps schools and colleges understand what they need to do to respond quickly and effectively when an incident occurs, or if they have concerns about a child, including all forms of sexual abuse.\nThe Everyone’s Invited testimonies have shown us the scale and nature of sexual abuse and harassment experienced by young people, often by their peers. The department acted quickly by asking Ofsted to carry out a thematic review into sexual abuse, the findings from which have now been widely reported and can be found here: https://www.gov.uk/government/publications/review-of-sexual-abuse-in-schools-and-colleges/review-of-sexual-abuse-in-schools-and-colleges. We have also set up a dedicated NSPCC helpline to support anyone who has experienced sexual abuse in educational settings or has concerns about someone or the issues raised.\nWe have already updated and published the information statutory guidance: Keeping Children Safe in Education (KCSIE), and Sexual Violence and sexual harassment between children in schools and colleges, both coming into force for this September. The updated guidance will ensure that schools and colleges, including DSLs, have even clearer guidance on how to deal with reports of sexual abuse, where to seek additional support (including engagement with the multi-agency safeguarding partners), help them make decisions when there are long-term investigations, harmful sexual behaviour, or when a criminal investigation does not lead to a prosecution or conviction. We will also update the Working Together to Safeguard Children statutory guidance in due course.\nWe will continue to develop our policies and engage with sector experts to understand the emerging risks and harms that children face, especially regarding peer-on-peer abuse, sexual exploitation, and online harms. As part of this work, we will keep the statutory guidance under review to update and strengthen as required, to ensure all schools and colleges have the guidance to meet their statutory duties to safeguard children. It goes without saying that we will thoroughly consider all the findings of the recent Ofsted report as part of this routine process. The work on the 2022 iteration of KCSIE has already started, including a cross-government review of the definitions of sexual abuse, including peer-on-peer, to consider how to better reflect the experiences of children and young people.\nWe are extending the DSL supervision trials, involving 30 local areas, to up to 10 further local authorities, with a specific focus on sexual abuse. The programme, led by What Works for Children’s Social Care, aims to strengthen support for designated safeguarding leads and will help build the evidence base on what works.\nWe are committed to developing an online resource hub for designated safeguarding leads where they can access relevant advice and guidance on a range of issues. The online resources will be developed with DSLs and relevant sector experts and made available in 2022. We will be working with the Centre of expertise on child sexual abuse to include resources on child sexual abuse.\nThe government will also undertake further work to consider how we can give greater status and support to designated safeguarding leads, looking first at the model we have for Special Educational Needs Coordinators.", "pred_label": "__label__POS", "pred_score_pos": 0.8725355267524719} +{"content": "ManChem’s COVID-19 Resource Centre Syndrome Coronavirus 2’ (SARS-CoV-2) was confirmed as the causative agent of what we now know as ‘Coronavirus Disease 2019’ (COVID-19). Cleaning and Disinfecting Your Building or Facility Close off areasused by the person who is sick. Companies do not necessarily need to close operations, if they can close off affected areas. Open outside doors and windowsto increase air circulation in the area. Wait 24 hoursbefore you clean or disinfect. If 24 hours is not feasible, wait as long as possible. Clean and disinfect all areas used by the person who is sick, such as offices, bathrooms, common areas, shared electronic equipment like tablets, touch screens, keyboards, remote controls, and ATM machines. Once area has been appropriately disinfected, it can be opened for use. Workers without close contactwith the person who is sick can return to work immediately after disinfection. If more than 7 dayssince the person who is sick visited or used the facility, additional cleaning and disinfection is not necessary. Continue routine cleaning and disinfection. This includes everyday practices that businesses and communities normally use to maintain a healthy environment.", "pred_label": "__label__POS", "pred_score_pos": 0.5064529776573181} +{"content": "Mindfulness-Based (MBCT) Therapists\nFor clients in Doylestown with chronic pain, hypertension, heart disease, cancer, and other health issues such as anxiety and depression, mindfulness-based cognitive therapy, or MBCT, is a two-part therapy that aims to reduce stress, manage pain, and embrace the freedom to respond to situations by choice. MCBT blends two disciplines--cognitive therapy and mindfulness. Mindfulness helps by reflecting on moments and thoughts without passing judgment. MBCT clients pay close attention to their feelings to reach an objective mindset, thus viewing and combating life's unpleasant occurrences.\nMindfulness Based therapists in Doylestown can help with issues like anxiety and depression in their role as Doylestown MBCT therapists.", "pred_label": "__label__POS", "pred_score_pos": 0.9826180338859558} +{"content": "Veterinary surgeons (vets) provide us with a fascinating platform to study anthropocentric and zoocentric beliefs, which we argue are gendered in both their genesis and practice. Gendered in the sense of the double meaning of our title ‘who's a good boy then?’, which reflects both a default male gender and a patronizing masculine claim to mastery over the animal. In addition, veterinary practices are organized in specifically masculine ways that, despite the demographic feminization of the profession, are oblivious to distinctively gendered practices and concerns and thus to the reproduction of gendered inequalities. The research also focuses on how there is a tendency for vets to neglect their own bodies for the sake of the animal's welfare (zoocentrism) but, at the same time, this reflects and reproduces masculine anthropocentric demands for human supremacy involving linear rational and effective control over the animal as a necessary part of their commercial and career success. In the empirical presentation, we show how organizational gendering within the gendered organization of veterinary surgery occurs at all levels, sometimes openly and explicitly, but also covertly and implicitly. In seeking to interrogate the covert and implicit in gender asymmetry, we draw on post‐humanist feminist philosophical perspectives that facilitate our challenging of the gendered anthropocentric organization of veterinary work.\nThis is the peer reviewed version of the following article: Clarke, C, Knights, D. Who's a good boy then? Anthropocentric masculinities in veterinary practice. Gender Work Organ. 2019; 26: 267– 287. https://doi.org/10.1111/gwao.12244 which has been published in final form at https://onlinelibrary.wiley.com/doi/full/10.1111/gwao.12244 This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.", "pred_label": "__label__POS", "pred_score_pos": 0.5464814305305481} +{"content": "Successful fundraising deals and attractive returns have resulted in burgeoning assets across PE funds globally. The value of these assets crossed an astounding USD4tn for the first time. The PE space has not only been growing but evolving and has adopted outsourcing as one of its boosters for growth. As per PwC, 70% of PE firms in Europe are actively outsourcing. Among US-based PE firms, approximately 30-40% have been outsourcing. PE funds have been outsourcing areas such as the tax function, compliance reporting, fund accounting, technology and even investor relations. Unsurprisingly, India is emerging as an outsourcing hub for PE firms.\nHere are some of the leading reasons why PE firms are outsourcing to India:\nCompliance-related requirements PE firms need to comply with several legal and regulatory requirements. For instance, as per the Foreign Account Tax Compliance Act and the Alternative Investment Fund Managers Directive, PE firms need to provide accurate and timely financial reports. Preparing these reports for these reports is a time consuming and vital task. Indian firms have capable accounting professionals and robust infrastructure to manage repetitive yet critical tasks such as on-demand financial reporting and accounting. The Indian outsourcing sector has been in existence for nearly two decades and is well equipped to take on such projects. This enables in-house PE professionals to focus on their core competencies, which include raising funds for unlisted companies. A mature PE landscape India emerged as the second-largest deal market in Asia-Pacific (APAC) in 2019 with more than 1,000 PE and venture capital deals valued at USD45bn. Large-scale PE firms in India have created a mature PE landscape in the country. India's share in the APAC deal market increased to ca.25% in 2019, with the value of investments increasing by 70 compared to the previous year. The consumer technology space attracted deals amounting to almost USD7.7bn. Sectors such as e-commerce, on-demand services, healthcare and software as a service (SAS) are poised to experience tremendous growth. Thus, India already has a mature PE landscape: there are individuals as well as processes that could play a crucial role in supporting PE infrastructure abroad. Access to world-class talent India has a huge talent pool of engineers, managers and accountants who are proficient in English. With the proliferation of cheap and accessible internet, Indian students and professionals have been investing in upskilling themselves. This talent pool is a compelling justification for PE firms to outsource their operations to India. Cost reductions Outsourcing offers long-lasting benefits and one of the most significant is cost reductions up to 30-70% in PE fund operations. Therefore, a significant share of management fees may be booked as fund profits. Outsourced solutions require less spending compared to in-house professionals. Plug-and-play model When the frequency of deals rises, the quantum of supporting activities would also increase. However, scaling up in-house teams may not be a viable solution, as a reversal in the trend would result in PE firms with oversized staff, which would have to be reduced and could lead to multiple complications . Outsourcing to India presents a plug-and-play model for private equity outsourcing, as they could ramp their outsourcing operations up and down as per demand. This optimises their operations and improves their margins. An extended work day Outsourcing to India means that work continues throughout the day due to time zone differences. When professionals in western countries end their day, their Indian counterparts would be starting work in the morning. The latter would be able to complete and submit their tasks in the evening and their colleagues in the western markets would be able to access important information and insights when they report for work. This significantly improves efficiency. Discreet due diligence Conducting due diligence of prospective investors is an extremely crucial activity. PE firms would not want their targets to know about these activities. Hence, it is suitable to outsource such activities to a firm based in India that could conduct extensive due diligence without the prospective investee getting a whiff of the impending deal.\nThe above-mentioned reasons are why most PE companies outsource to India.", "pred_label": "__label__POS", "pred_score_pos": 0.8951029181480408} +{"content": "We present the first approach to volumetric performance capture and novel-view rendering at real-time speed from monocular video, eliminating the need for expensive multi-view systems or cumbersome pre-acquisition of a personalized template model. Our system reconstructs a fully textured 3D human from each frame by leveraging Pixel-Aligned Implicit Function (PIFu). While PIFu achieves high-resolution reconstruction in a memory-efficient manner, its computationally expensive inference prevents us from deploying such a system for real-time applications. To this end, we propose a novel hierarchical surface localization algorithm and a direct rendering method without explicitly extracting surface meshes. By culling unnecessary regions for evaluation in a coarse-to-fine manner, we successfully accelerate the reconstruction by two orders of magnitude from the baseline without compromising the quality. Furthermore, we introduce an Online Hard Example Mining (OHEM) technique that effectively suppresses failure modes due to the rare occurrence of challenging examples. We adaptively update the sampling probability of the training data based on the current reconstruction accuracy, which effectively alleviates reconstruction artifacts. Our experiments and evaluations demonstrate the robustness of our system to various challenging angles, illuminations, poses, and clothing styles. We also show that our approach compares favorably with the state-of-the-art monocular performance capture. Our proposed approach removes the need for multi-view studio settings and enables a consumer-accessible solution for volumetric capture.\nIn this section, we describe the overall pipeline of our algorithm for real-time\nvolumetric capture (Fig. 2). Given a live stream of RGB images, our goal is to\nobtain the complete 3D geometry of the performing subject in real-time with\nthe full textured surface, including unseen regions. To achieve an accessible\nsolution with minimal requirements, we process each frame independently, as\ntracking-based solutions are prone to accumulating errors and sensitive to\ninitialization, causing drift and instability [49, 88]. Although recent approaches\nhave demonstrated that the use of anchor frames [3,10] can alleviate drift, ad-hoc\nengineering is still required to handle common but extremely challenging scenarios\nsuch as changing the subject.\nFor each frame, we first apply real-time segmentation of the subject from the background. The segmented image is then fed into our enhanced Pixel-Aligned Implicit Function (PIFu) [61] to predict continuous occupancy fields where the underlining surface is defined as a 0.5-level set. Once the surface is determined, texture inference on the surface geometry is also performed using PIFu, allowing for rendering from any viewpoint for various applications. As this deep learning framework with effective 3D shape representation is the core building block of the proposed system, we review it in Sec. 3.1, describe our enhancements to it, and point out the limitations on its surface inference and rendering speed. At the heart of our system, we develop a novel acceleration framework that enables real-time inference and rendering from novel viewpoints using PIFu (Sec. 3.2). Furthermore, we further improve the robustness of the system by sampling hard examples on the fly to efficiently suppress failure modes in a manner inspired by Online Hard Example Mining [64] (Sec. 3.3).\nTo reduce the computation required for real-time performance capture, we\nintroduce two novel acceleration techniques. First, we present an efficient surface\nlocalization algorithm that retains the accuracy of the brute-force reconstruction\nwith the same complexity as naive octree-based reconstruction algorithms.\nFurthermore, since our final outputs are renderings from novel viewpoints, we\nbypass the explicit mesh reconstruction stage by directly generating a novel-view\nrendering from PIFu. By combining these two algorithms, we can successfully\nrender the performance from arbitrary viewpoints in real-time. We describe each\nalgorithm in detail below.\nOctree-based Robust Surface Localization. The major bottleneck of the pipeline\nis the evaluation of implicit functions represented by an MLP at an excessive\nnumber of 3D locations. Thus, substantially reducing the number of points to\nbe evaluated would greatly increase the performance. The octree is a common\ndata representation for efficient shape reconstruction [87] which hierarchically\nreduces the number of nodes in which to store data. To apply an octree for an\nimplicit surface parameterized by a neural network, recently [45] propose an\nalgorithm that subdivides grids only if it is adjacent to the boundary nodes\n(i.e., the interface between inside node and outside node) after binarizing the\npredicted occupancy value. We found that this approach often produces inaccurate\nreconstructions compared to the surface reconstructed by the brute force baseline\n(see Fig. 3). Since a predicted occupancy value is a continuous value in the range\n[0, 1], indicating the confidence in and proximity to the surface, another approach\nis to subdivide grids if the maximum absolute deviation of the neighbor coarse\ngrids is larger than a threshold. While this approach allows for control over the\ntrade-off between reconstruction accuracy and acceleration, we also found that\nthis algorithm either excessively evaluates unnecessary points to perform accurate\nreconstruction or suffers from impaired reconstruction quality in exchange for\nhigher acceleration. To this end, we introduce a surface localization algorithm\nthat hierarchically and precisely determines the boundary nodes.\nWe train our networks using NVIDIA GV100s with 512 × 512 images. During\ninference, we use a Logitech C920 webcam on a desktop system equipped with 62\nGB RAM, a 6-core Intel i7-5930K processor, and 2 GV100s. One GPU performs\ngeometry and color inference, while the other performs surface reconstruction,\nwhich can be done in parallel in an asynchronized manner when processing\nmultiple frames. The overall latency of our system is on average 0.25 second.\nWe evaluate our proposed algorithms on the RenderPeople [57] and BUFF datasets [82], and on self-captured performances. In particular, as public datasets of 3D clothed humans in motion are highly limited, we use the BUFF datasets [82] for quantitative comparison and evaluation and report the average error measured by the Chamfer distance and point-to-surface (P2S) distance from the prediction to the ground truth. We provide implementation details, including the training dataset and real-time segmentation module, in the appendix. In Fig. 1, we demonstrate our real-time performance capture and rendering from a single RGB camera. Because both the reconstructed geometry and texture inference for unseen regions are plausible, we can obtain novel-view renderings in real-time from a wide range of poses and clothing styles. We provide additional results with various poses, illuminations, viewing angles, and clothing in the appendix and supplemental video.", "pred_label": "__label__POS", "pred_score_pos": 0.8210353851318359} +{"content": "This article looks firstly at the consequences of sleep deprivation and fatigue. We then provide some tips which you can try to sleep better—before you resort to medication.\nA recent study with significant implications for nursing care found that even minor sleep deprivation can increase pain sensitivity and cause a drop in the neurotransmitters that relieve pain.\nIndividuals should need to realize the importance of sleep and its relation to fulfillment, productivity, and activity. Here are seven sleep-promoting tips nurses must share to their clients:", "pred_label": "__label__POS", "pred_score_pos": 0.9682071805000305} +{"content": "If you have your own car insurance, you likely don't need to purchase additional car insurance for your rental car. You should check your insurance policy or call your insurer to make sure, but most policies extend the definition of your \"covered vehicle\" to any vehicle you rent.\nIf you don’t have a debit or credit card, you can still rent a car. A number of national car rental companies accept cash deposits, though be aware that those that do often require hefty deposits and the completion of extra paperwork.", "pred_label": "__label__POS", "pred_score_pos": 0.9448927640914917} +{"content": "Beyond the classifier/gender dichotomy Beyond the classifier/gender dichotomy\nThe role of flexibility in a more integrated typology of nominal classification\nThe entrenched nature of the gender/classifier dichotomy stands in the way of better typologies of nominal classification. How can we move beyond it to a more integrated view of nominal classification? Looking at a range of kinds of data from the Australian language Mawng, it is clear that our understanding of many less well-known nominal classification systems reflects a lack of data on how the system is used. Mawng has what seems like a well-behaved system of five genders, including gender agreement in the verb. However, the genders, like classifiers, play a crucial role in constructing meaning in discourse, often in the absence of nouns. Nominal classification systems must be contextualized in terms of their roles in constructing meaning in discourse, in order to do them justice in typologies. Greater emphasis on the flexibility of nominal classification systems and less on the role of nouns will also move efforts forward.\nOxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.\nIf you think you should have access to this title, please contact your librarian.", "pred_label": "__label__POS", "pred_score_pos": 0.8649106621742249} +{"content": "One more federal court has come out against proceeding with expensive and potentially unnecessary class discovery pending the resolution of dispositive motions.\nThe facts are straightforward: In\nSilva v. Connected Investors, No. 7:21-CV-74-BO , 2021 U.S. Dist. LEXIS 176184 (E.D.N.C. Sept. 16, 2021), defendant filed a motion to stay discovery while its motion for judgment on the pleadings in a putative TCPA class action was pending. Defendant highlighted that the motion, if successful, had the potential to dispose of the entire case, which would moot the need for class discovery. Defendant also pointed to the broad-reaching class discovery Plaintiff had requested, and highlighted the burden involved in responding to that discovery.\nAlthough Plaintiff opposed, claiming four months into the litigation was too late for the request and arguing potential prejudice via the loss of evidence from third parties, the Court found for defendant. It agreed that defendant’s motion could terminate the entire litigation, and observed that discovery was not necessary to resolve the motion for judgment on the pleadings. As for any prejudice to Plaintiff, the Court found that this prejudice was outweighed by the prejudice to\ndefendant if it were forced to engage in costly and broad-reaching class discovery.\nNotably, the Court granted defendant’s motion even after a scheduling order was entered, and after defendant’s discovery responses were due.\nSilva affirms the important point that there is no reason to proceed with costly class discovery while dispositive motions that could dispose of the entire case are pending – especially where there is a significant burden in responding to that discovery", "pred_label": "__label__POS", "pred_score_pos": 0.5030192136764526} +{"content": "To overcome the inefficiencies and challenges faced in traditional VMS camera deployments, QCIC were engaged to provide an innovative and turnkey solution both in the Asia-Pacific (APAC) and North America regions.\nThe overall objective of our client, a leading global consulting firm, was to minimise the number of interruptions of live working sites. Equally, we set an aggressive programme – so solutions that speeded up installation and deployment were critical whilst delivering on time and within budget.\nStrategy/process taken during the project\nQCIC has developed a process to seamlessly automate the project from design through to the delivery-to-site of pre-programmed cameras.\nOur Direct-to-Site delivery ensures that through the automation of design processing, the required security equipment arrives on-site, pre-programmed along with the necessary design documentation and without the unnecessary waste. We achieve this via our innovative automation software and selected distribution partners. The result is a simple plug-and-play deployment with significant time saved, both in the procurement process and on-site configuration.\nOur designs for this project incorporated intelligent icons that held all of the required information for the equipment and pre-programing. Working in collaboration with our distribution partners, 1 500 cameras for APAC and 500 cameras in North America would be pre-programed, tested and repackaged, ready for dispatch and delivery.\nThe pre-programing, testing and smart-packaging of the units significantly reduced the possibility of any “dead on arrival” units and lowered freight costs and wastage, offering our client sustainability benefits.\nOutcome\nThe automation tool allowed all the required information to be populated within smart icons that were placed onto the design drawings, coupled with the central reference information specific to the project. Via this process, full documentation was supplied to our pre-configuration partners to prepare the equipment and dispatch pre-kitted and tested cameras ready for an expedient installation at the associated locations across the globe. Once the cameras were fixed and connected, we were then able to remotely and automatically configure them “over the air” by way of the automated importer tool. This removed the need for physical personnel on-site and vastly sped-up the process, delivering a higher degree of accuracy across the project.\nBenefits of using Direct-to-Site delivery include automation of the design and documentation process, streamlined engagement with the pre-configuration/distribution partners, more detailed and environmentally friendly shipping and packing, significant reductions in labour, on-site, installation, engineering, software, freight and commissioning costs.\nThese benefits promise: 95% recycled waste at source 66% reduction in on-site activities 38% reduction in total labour hours 45% reduction in delivered volum\nThe use of the auto mini-importer versus a manual data entry method delivered a saving of 83 hours in North America and a saving of 250 hours in the APAC region.", "pred_label": "__label__POS", "pred_score_pos": 0.6192021369934082} +{"content": "Care for older Adults\nPeople like to feel seen and heard, also when they become older. Older adults prefer to continue living their lives the same way as they used to do, even when they become dependent on care and support from others. Person-centered care enables this by putting individuals’ preferences and values at the heart of care decisions. As such, person-centered care focuses on maintaining the older adults’ identity, autonomy and their independence.\nWithin the Academic Collaborative Center (ACC) Care for Older Adults of Tranzo, older adults, (care professionals of) care organizations and scientists closely collaborate in realizing person-centered care for (vulnerable) older adults living at home and in nursing homes. The ACC conducts social scientific research on the perspectives of (vulnerable) older adults. By bundling the knowledge and skills of scientists, healthcare professionals and older adults themselves, research findings clearly provide insight into the preferences, values and goals of older adults. These insights are used to evaluate and innovate care. As such, we strive for older adults to be recognized as unique individuals and as equal partners in healthcare and to realize more person-centered care.\nThe ACC Care for Older Adults is led by\nEvents\nKnowledge exchange within Tranzo is important: - Symposia - Promotions and inaugurations", "pred_label": "__label__POS", "pred_score_pos": 0.8537015914916992} +{"content": "Dog Park Do’s and Don’ts\nA dog park can be a great place for your dog to exercise and 'socialize. It can, however, become a source of trauma for him. The behavior of your fellow dog owners has a big impact on your experience. A few obnoxious people can ruin your and your dog's experience.\nSimply follow these simple etiquette rules for a more enjoyable bark park experience for everyone:\nDO'S\nBring everything you'll need. Bring a bowl of water and a bowl from home. Cleaning towels and car seat covers are also a good idea. After all, a romping, running pack of dogs is bound to get filthy. Remember to bring something to clean up after your dog as well.\nAllow your dog to just be a dog. Spend some time observing dogs playing in a group if you don't know the difference between rough play and real dogfighting. Many dog owners have been known to panic when they see their dogs at the bottom of a dog pile for the first time.\nMake sure your dog is wearing identification. You may use a tag or information on your dog's collar. Before allowing dogs free to play, replace training collars with buckle collars or a harness—training collars may become hooked in the teeth of other dogs, resulting in serious consequences. Better yet, use a harness.\nKeep your dog on a leash until you've reached the park's perimeter. After entering the off-leash area, remove your dog's leash. When on-leash and off-leash dogs are together, the leashed dogs may become stressed, which may lead to violent behavior.\nKeep an eye on your dog while he is playing. It's tempting to bury your head in today's newspaper but resist the urge. Whether your dog is the culprit or the victim, be ready to stop improper play.\nTo prevent possible disputes, limit the usage of toys or food rewards. Depending on how many dogs are at the park when you come, you may modify this guideline.\nCheck to see whether your dog understands simple instructions. The most essential commands are \"come,\" \"sit,\" and \"leave it/off,\" which may help you manage your dog if required and prevent him from irritating others.\nDON'TS\nDon't bring a dog with a history of misbehavior. If your dog's behavior is unpredictably unpredictable, he should be socialized in more controlled settings than a dog park.\nIf your dog has been ill in the previous 48 hours, don't bring him. If you're unsure, consult your veterinarian.\nDon't punish a dog that belongs to someone else. If you don't like another dog's behavior, take your dog out of the park instead of correcting another dog's.\nOther dogs should not be fed. You have no idea whether their owners agree, and your goodies may disrupt another dog's diet or stomach. It may also cause dogs to become envious of one other.\nIf your dog isn't having a nice time, don't remain. Some canines prefer a small group of pals over large groups. Some pups love playing in the park, but as they get older, they become less interested.\nOne more piece of advice: don't wear white and don't bring a dog that has just been groomed. Neither of you will go unnoticed when you get home.", "pred_label": "__label__POS", "pred_score_pos": 0.8019305467605591} +{"content": "Trauma-Informed Embodiment Yoga\nThe research is evident- trauma impacts our bodies - how we nurture the body, how we hold ourselves, how we protect our bodies, how we move through the world.\nDissociation and disidentification from the body is often a trauma response. It can result in faulting the body, misunderstanding what and why the body is, and sadly, not knowing how to befriend the physical body without judgment, fear, frustration, and condemnation.\nOur team is committed to dissolving any barriers to the healing practice of connecting the mind and the wisdom of the body through breath and gentle movement. We invite you to join us whether or not you have practiced before, regardless of what shape you are in or what shape you are.\nOur Yoga practice is a personal and private journey into oneself - it is not about how far you can flex or balance. It is about how much you can simply feel and be.\nIf you have ever looked at yoga and thought \"I can't bend like that\" but you are curious and want to embark on a journey to return home to your body...\nWelcome to Trauma Respectful and Embodiment Yoga!\nThe Philosphy:\nWe honor yoga as a practice that supports embodiment rather than flexibility - we are open to all individuals and all levels. You do not need any prior experience to take part in these sessions. All participants will be met with respect and are welcome.\nIntentions of our journey:\n- Judgment free observation of how your body is feeling\n- Recognize what brings you comfort\n- Understanding of how to seek comfort\n- Ability to connect to your sense to feel grounded\n- Develop a personal supportive “toolbox”\nFrom Couch to Mat\nPart 1 - Intake\nThe intake and assessment process is an online meeting to understand what your personal barriers and fears may be. How your trauma holds in the body and how yoga can heal trauma.\nWe explore what your unique needs are in order for your to start feeling comfortable being present within your body to support your trauma counseling process.\nWe will honor and gently explore what types of movements would be helpful for you and which to avoid at this time.\nDuring this meeting we may also explore your personal \"dhosha\" tendencies and provide resources which may be helpful.\nThere is no yoga movement during the intake and assessment meeting.\nPart 2 - Practice\nAfter your initial assessment, you will be invited to either individual, group practices, or both.\nIndividual practice will be private one-to-one yoga therapy practices scheduled at a time convenient to you and your trained practitioner.\nGroup practices will be held weekly and your intake and assessment will influence the series of movements (vinyasa) the teacher will suggest as you move through the practice together. During the class options will always be provided to ensure you are experiencing the \"purpose\" of the pose rather than the esthetics of the pose.\n*Unless noted, all sessions are provided by trained yoga therapists and mental health therapists with specialized training in trauma-informed yoga.\nInsurance Receipts are available for appointments with our mental health therapists.\n* no equipment necessary though we suggest:\na journal\ncomfy clothes\na mat\nsome pillows and blankets\na water bottle\na small stool if you like\nsome wall space if you prefer", "pred_label": "__label__POS", "pred_score_pos": 0.5496509075164795} +{"content": "Paraguay, located in middle South America, is bordered by Bolivia, Brazil, and Argentina. It is home to approximately 6.5 million people. Paraguay’s capital is Asuncion.\nYou might need to ship your household goods, such as furniture and clothing if you’re moving to Paraguay. Learn important rules and regulations before shipping cargo to Paraguay. Paraguay customs officials will inspect any cargo shipment that arrives at the port or airport, even if it is not a diplomatic shipment.\nParaguay citizens who are returning home from abroad and want to ship goods home must have lived in Paraguay for at least two years to be eligible to import personal items duty-free. These documents are required if you want to qualify for Paraguay duty-free shipping.\nYour Paraguayan Identification\nYou will need identification or something similar in the country you are leaving. Paraguayan Consulate in origin. Please note that you must give these documents to Asuncion’s Repatriation Office to receive a Repatriation Certificate. You are not allowed to import vehicles to Paraguay duty-free. Temporary Residents Ship Cargo to Paraguay\nYou should be aware of crucial information if you’re not a Paraguayan but would like to ship cargo to the country as a temporary resident.\nTo ship household goods or personal items to Paraguay, you will need a temporary resident permit. These permits can be valid for up to 12 months. You will need to pay import taxes and duty fees on the goods you send.\nForeign Diplomats Ship Cargo to Paraguay\nForeign diplomatic personnel and individuals who work with international organizations: To receive your accreditation from the Paraguayan government, you should be in Asuncion no less than three weeks prior to your shipping container arrives.\nYou can import household goods, personal effects, and one vehicle to Paraguay with the diplomatic franchise.\nPermanent Residents Sea Shipping to Paraguay\nA Paraguay permanent resident permit (valid for up to a decade) allows you to import household goods and personal effects duty-free. A Customs Certificate is required. This can be obtained by bringing the necessary paperwork to Asuncion’s Immigration Office.\nA residence permit is required depending on your status. To legalize the documents, you must first present all required paperwork to the Ministry of Interior (MOFA) and Ministry of Foreign Affairs. You can then submit all documents to Paraguay’s Immigration Office.\nThe customs certificate can only be issued within the first six months of obtaining the residence permit. Duties must be paid after this period of six months.\nParaguay: Items Prohibited or Restricted\nParaguay has some restrictions on cargo shipping. These include the following:\nMachines for making currency\nDaggers and hatchets, firearms, or swords Books, films, or other materials that are immoral or inappropriate Paintings Any equipment used in war, including arms and military machinery Paraguay Car Shipping\nParaguay is not permitted to receive vehicles older than ten years old if you wish to ship a car there.\nParaguay is a destination for car shipping. You will need to provide the following documentation:\nThe original invoice for commercial purposes\nOriginal vehicle title Paraguay Permanent Residence Permit You may have to pay duties fees if you ship a car, or any other vehicle, to Paraguay. The duty fees range from 35% to 40% above the Paraguayan customs officials’ value. This is an exception for diplomatic shipments. Port taxes are required for all diplomatic shipments.", "pred_label": "__label__POS", "pred_score_pos": 0.5014934539794922} +{"content": "With copyright protection entering the influencer-marketing picture, brands must prepare to empower creators.\nA TikTok creator was recently granted the right to copyright popular choreographed moves using labanotation. The process records bodily movements using symbols and specific patterns aligned with musical accompaniment. This is a significant development in an ongoing conversation to empower creators and grant them protection for their IPs while collaborating with brands.\nAs brand-influencer collaborations move to become more equitable for all parties involved, creators may seek to align production timelines with copyright timelines. Now that copyright clauses are making their way to contracts, brands should also prepare to negotiate more complex agreements.\nBrands should now make creators feel valued by crediting creators who inspire brand campaigns and establish clear compensation standards. More importantly, adapt to changing times and empower creators to secure copyright protection.\n[4 minute read]", "pred_label": "__label__POS", "pred_score_pos": 0.9903454184532166} +{"content": "Successful internal mobility is a key to retention of high-performing employees, their deployment in suitable positions, and their career development. Psychometric tools can therefore provide invaluable insights for effective internal mobility processes that encourage long-term productivity and engagement.\nJoin us on\nWednesday, July 28th at 11:00 am CEST We shall explore & discuss: What is internal mobility and why is it important? The role of psychometric assessments in internal mobility Actionable advice for effective internal mobility 3 key assessments for successful internal mobility Live Q&A chat Speakers Victoria Gosling, R&D Project Manager - Central Test Diksha Unni, Asst. R&D Manager & Sr. Consultant - Central Test", "pred_label": "__label__POS", "pred_score_pos": 0.9934214353561401} +{"content": "Abstract\nChallenges and opportunities in multi-scale computational modeling of (photo-) electrocatalytic processes Author(s):Tadashi Ogitsu\nRenewable energy sources, such as solar and wind energies, are intermittent in nature and show large variation in its geographical distribution, leading to necessity of scalable energy storage and re-distribution solutions. Hydrogen and hydrogen rich organic species are good candidates for such energy carrier due to its abundance of constituent elements and their high energy densities that stems from the low atomic weight of hydrogen. While methodologies for synthesizing such energy carriers already exist, further improvements are necessary for accelerating mass deployment of renewable energy.", "pred_label": "__label__POS", "pred_score_pos": 0.9502724409103394} +{"content": "Though a small percentage, some individuals with autism and other developmental disabilities can display dangerous challenging behaviors such as high intensity aggression or self-injury. While the field of applied behavior analysis has made great strides in the assessment and treatment of challenging behaviors, effectively applying that technology increases in difficulty as individuals’ profiles become more complex. In addition to a diagnosed developmental disability, those served at Melmark often also have several other factors contributing to their challenging behaviors. These can include co-occurring mental health diagnoses, impaired communication abilities, social skill deficits, unique sensory profiles, and complex medical needs. This means any treatment plan must balance all of these factors, even when the treatment recommendation for one factor contradicts the recommendation for another.\nGuided by our values as expressed through our core commitments of\ncompassionate care, integrity in everything we do, highly skilled workforce, evidence-based practices, and ensuring best outcomes for all, Melmark built its model to provide this level of comprehensive assessment and treatment for every person who walks through our doors, ensuring them the best chance at a meaningful and productive life. Assessment\nAll treatment planning at Melmark begins with thorough assessment. Assessment allows us to understand the person, mapping out their strengths and needs, and finding clues as to why they may be engaging in such dangerous behavior.\nSome of the first assessments we conduct are designed to explore what the individual enjoys. These preference assessments help identify reinforcers, but also provide insight into how to design each individual’s day to ensure an enjoyable and supportive environment. Thorough skill assessments are also conducted to determine areas of strength, as well as where additional support and training is necessary for folks to successfully navigate their environment. This can include assessing skills related to adaptive behavior, academics, daily living, social, communication, and more.\nAs a behavior analytic program, a functional behavior assessment (FBA) also begins immediately to identify environmental variables that may evoke and maintain targeted behaviors. With the complex profiles we serve, initial results are often inconclusive. In this case, individual variables are tested directly via a functional analysis. Identifying these variables is critical to pinpoint exactly what makes certain scenarios so challenging for someone. Once identified, we can effectively prevent some of those scenarios, make those scenarios less aversive when they do occur, and teach skills to navigate those situations more successfully. In addition to analyzing the immediate situations, a comprehensive FBA also includes the assessment of variables that are harder to detect. We systematically collect data and analyze the impacts of factors such as sleep patterns, medication, bowel movements, hydration, and more to include in treatment programming.\nIt is worth noting this is not an exhaustive list of assessments. If there is a variable that could be important, Melmark has likely assessed it in some way. We regularly develop custom assessments to examine the influence of idiosyncratic variables. For example, when we hypothesized that an individual exhibited challenging behavior to access the physical intervention required to maintain safety, we tested different types of physical interaction, identified the most preferred type, and then taught the individual to request this preferred physical attention instead of exhibiting aggression.\nAddressing Unmet Wants and Needs\nAfter assessment, planning begins. The first step in intervention is to ensure access to a healthy, supportive, and enjoyable environment. As such, schedules are developed for individuals that blend instructional, leisure, social, and community activities.\nThe specifics of how these activities look changes for each individual, guided by assessment results. For instance, instruction is tailored to the person’s skill level and learning profile. Recreational activities and interaction styles incorporate results from preference assessments. Social opportunities are customized to ensure everyone has meaningful social engagement. Plans are created to ensure each person’s medications and health procedures are implemented, diets are adhered to, sleep schedules are implemented and tracked, and more. All of this effort forms the strong foundation upon which all other interventions are added.\nThis is not always an easy task as challenging behaviors can interfere with an individual’s ability to participate in these activities. However, we remain dedicated and commit the resources necessary to support individuals through their day. If an individual can access this type of environment, the need to engage in challenging behaviors at all decreases dramatically.\nImmediate Environmental Adaptations\nEven with a strong foundation, challenges still occur. A peer may not respond as anticipated, preferred activities may not always be available, or it may be necessary to work on a skill that is particularly hard for someone. That is why, as part of our compassionate planning, the next step is to look at how to make such situations less aversive.\nTargeted interventions to address challenging situations are incorporated. Some empirically-supported strategies to achieve this goal include: reducing the magnitude of aversive stimuli (e.g., dimming bright lights), incorporating preferred stimuli into challenging activities proactively, signaling the length of challenging situations and delay to preferred activities through the use of schedules and visual supports, and providing some level of control through choice making.\nTeaching and Increasing Appropriate Behaviors\nTo ensure best outcomes for individuals, we must also include evidence-based skill building. While making the environment supportive and reducing the obstacles challenging situations present is important, teaching the folks we serve how to succeed in a less structured environment is critical for their long-term success. Therefore, once the environment is planned for, we move to planning for skill building.\nThis is also a two-pronged strategy, encompassing teaching broader, foundational skills alongside skill building targeted for challenging situations. Broadly speaking, the skill assessments inform us of what adaptive skills need to be targeted. For instance, if an individual has difficulty with activities of daily living such as getting dressed, it may be because they lack the ability to perform these tasks fluently. Similarly, an individual may be resistant to solving algebraic formulas or sustaining peer interactions because they do not have the prerequisite skills. In all of these cases, plans are implemented to build the skills to complete these activities.\nSimultaneously, we also teach skills that give individuals the ability to respond immediately and appropriately to the challenging situations, to help them navigate those times while the long-term skills are being acquired. For instance, if the FBA reveals an individual becomes aggressive when presented with a task to avoid it, we might teach the individual to ask for short breaks so they can escape the tasks without needing to escalate to aggressive behavior. We may also layer in a reinforcement program for completing the task without exhibiting challenging behaviors. This way the person can get away from the task when they need to, but is still motivated to receive instruction on the task. This way they acquire the skills necessary to complete it independently over time.\nFor complex individuals, this can take months or years to fully shift to more adaptive options. However, we remain patient and support them through the acquisition of these critical skills because we know it will increase the likelihood of successful long-term, best outcomes.\nResponding to Challenging Behaviors Safely\nFinally, even with all the proactive supports in place, we must have a plan for how to respond to challenging behavior. Anytime we make a plan to respond to dangerous behavior, we always ensure the safety of the individual and those around them.\nOnce safety is secured, we plan to ensure any reinforcement received for challenging behaviors is of a lower quality than reinforcement for appropriate behaviors. This is important, as sometimes it is not possible to avoid reinforcing challenging behavior. For instance, if an individual engages in severe self-injury to access attention, staff must intervene to protect that person, thus providing some level of attention for safety. However, such interactions should be more neutral if challenging behavior is occurring while high-quality attention should be available throughout the day and provided immediately following appropriate behavior. In this way, the individual is likely to learn that the better option is to use appropriate behavior to gain access to high-quality attention.\nLast, we constantly review plans to ensure individual rights are protected. Due to the complexity of the population Melmark serves, interventions that are more restrictive than we would like, such as non-violent physical intervention, are sometimes necessary. The decision to use restrictive interventions is never taken lightly, and always weighed in consideration with every individual’s rights. As such, we regularly review interventions to ensure every step is taken to protect people’s rights when a restrictive procedure is called for.\nOngoing Data Monitoring\nAll of the work described thus far is a fair description of what goes into making a plan for individuals we serve. However, it does not end there. Our staff must be trained to implement the plan. With so many different components, this is no small feat, which is why we ensure all of our staff are highly skilled through extensive and ongoing training.\nData collection occurs in real time on all of the metrics that have been targeted including rates of challenging behaviors, acquisition of new skills, physiological factors, safety indicators, and more. These data are reviewed on a biweekly basis to ensure progress. This rigorous data collection and review allows us to pivot as needed to respond to the shifting needs of those we serve. It also allows us to identify issues that may have been masked initially. As our plan controls for so many variables, new patterns of responding can reveal additional factors. For example, a person may come to us exhibiting high rates of challenging behaviors across a myriad of activities. However, once we control for the majority of the operant variables, we can see challenges consolidate around certain activities such as bathroom trips. A medical follow up may diagnose an undetected condition, allowing for us to put the final piece of the puzzle of treatment into place.\nConclusion\nThe process described here is intensive. The layers of assessment and intervention requires significant skill and investment to ensure it is done with fidelity. Adhering to our core commitments, this is the only way to proceed to ensure those we serve achieve the\nbest outcomes possible.\nForemost, this means having\ncompassionate care as the basis of our intervention plans. Compassionate care begins with foundational values including humane treatment, the preservation of dignity, and a focus on increasing choice, control, and competence. It extends to maximizing the individual’s agency and involvement in their care, incorporating preferences and choices into every aspect of intervention, and involving the individual in their own care and treatment planning in every way possible. It also applies to responding to challenging behaviors, where interventions are administered in the context of humane care that focuses on maximizing the individual’s quality of life.\nWith compassion as the foundation, we look to our other commitments to ensure successful implementation of those compassionate and comprehensive plans. This means selecting interventions that are\nsupported by evidence so they have the best chance at success. It also means investing in a highly-skilled workforce, which allows us to be confident that our staff have the skills and sophistication to craft such nuanced plans and implement them fidelity. Finally, it means administering every step of the process with integrity, so they we are able to deliver the highest quality services to every individual, every day. Resources\nFor further reading, see the following resources addressing compassionate care, essential components of a behavior plan, and a model for comprehensive behavior planning.\nLeBlanc, L. A., Taylor, B. A., and Marchese, N. V. (2020). The training experiences of behavior analysts: Compassionate care and therapeutic relationships with caregivers. Behavior Analysis in Practice, 13, 387-393. O’Neill, R. E., Albin, R. W., Storey, K., Horner, R. H., & Sprague, J. R. (2014). Functional assessment and program development. Cengage Learning. Quigley, S. P., Ross, R. K., Field, S., & Conway, A. A. (2018). Toward an understanding of the essential components of behavior analytic service plans. Behavior Analysis in Practice,11, 436-444. Taylor, B. A., LeBlanc, L. A., & Nosik, M. R. (2019). Compassionate care in behavior analytic treatment: Can outcomes be enhanced by attending to relationships with caregivers? Behavior Analysis in Practice, 12, 654-666. Bradley S. Stevenson, PhD, BCBA-D, is Director of Program Administration and Clinical Services, Jill Harper, PhD, BCBA-D, LABA, is Senior Director of Professional Development, Kylee Formento, MA, BCBA, is Director of Children’s Clinical Services, Shawn P. Quigley, PhD, BCBA-D, is Executive Director, PA Division, and Frank L. Bird, MEd, BCBA, LABA, is Vice President & Chief Clinical Officer at Melmark Inc. For more information, please visit www.melmark.org .", "pred_label": "__label__POS", "pred_score_pos": 0.9577534794807434} +{"content": "Sportspeople are prone to injuries during sporting events. Therefore, installing quality sports flooring and maintaining it is a critical step to avoiding falls. Although most fans keep on cheering, they may not understand the importance of quality sports flooring. Moreover, sports flooring may resemble conventional flooring, but there are significant differences. Traditional floors are rigid and can pose serious strain to anyone undertaking physical exercises. On the other hand, sports flooring employs carefully selected materials to ensure comfort and enhance player performance.\nCheck out the benefits of sports flooring to athletes: Better traction\nQuality sporting surfaces allow for easy and safe movement in multiple directions. The floor surface is designed to offer the right amount of traction, allowing for easy and quick action. Sports flooring also ensures better bounce and balance during play.\nIf there’s too much traction, this can hinder movement, while too little traction hinders movement and stability. Most injuries occur on sporting floors due to slips and falls. Such sporting surfaces don’t offer proper traction, thus causing too much friction.\nHowever, it’s advisable to choose the best flooring materials depending on the type of sporting activity. For instance, recycled rubber flooring is ideal for weight rooms, while wooden flooring suits indoor soccer, volleyball, and basketball.\nImproved playability& Noise reduction\nQuality sports flooring offers adequate levels of ball bounce. It has a consistent bounce throughout the court, which helps avoid unresponsiveness among athletes. Distractions are also worth mentioning and are common in traditional flooring.\nDistractions can lead to accidents and injuries, which can be fatal. To avoid accidents and noise distractions, install quality sports flooring. Additionally, use the right underlayment material in the sub-flooring.\nQuality sports flooring is easy on the joints.\nShock absorption is a critical aspect of sports. A floor with excellent shock absorption properties helps decrease injuries among athletes. These can result from wrong landing, bumping into other players, or falls. Sporting accidents can lead to long-term injuries, and you can easily prevent them by installing sports flooring.\nSuch floors have high shock absorption properties and are friendly to athlete’s joints. For instance, sports like basketball involve constant running and jumping and can be hard on the legs. However, quality sports flooring can help prevent ligaments to the ankles, knees, and feet.\nWhy is wooden sports flooring popular?\nWooden sports floor is renowned for its many benefits. It’s common in most sporting fields and home gyms alike. It’s easy to clean and maintain, and wiping spills shouldn’t be an issue. Also, it’s durable and can withstand different sports without wear.\nWood is famous for its excellent shock absorption properties, which help prevent injuries using sporting events. Can I tell you more? Wooden flooring comes in different colors and patterns, and it’s quite appealing.\nConclusion\nSports flooring benefits players in multiple ways. It helps avoid severe injuries and improves playability for enhanced performance. If you’re seeking to install high-quality flooring for your sporting field or home gym, acquire it from experts. You can only be sure of quality when shopping from reputed companies or manufacturers.", "pred_label": "__label__POS", "pred_score_pos": 0.6491127014160156} +{"content": "abstract\nThis experiment assessed the efficacy of proprioceptive and visual information for the performance of “vertical position” by synchronized swimmers. Three skill groups of 5 senior, 5 intermediate, and 5 novice synchronized swimmers performed 40 vertical positions under four conditions. The conditions were: self-initiated with and without vision, and following experimenter perturbation, with and without vision. The dependent measure was degrees of error from true vertical. Analysis indicated that either proprioception or proprioception and vision may be used in performing vertical positions. A significant main effect was found among skill groups.", "pred_label": "__label__POS", "pred_score_pos": 0.9329649209976196} +{"content": "As part of the national strategy on overdose prevention and response, the SPVM is contributing to the collective drive, supported by the Gouvernement du Québec. From October 19 to November 9, 2020, almost 3,300 police officers took an online training course run by the École nationale de police du Québec to learn how to administer naloxone with a nasal spray. This medication is used to temporarily reverse the effects of an opioid overdose and consequently save lives.\nBeginning November 10, 2020, the SPVM has distributed 174 naloxone kits to 30 neighbourhood police stations and 26 operational support units. From November 10 to December 31, 2020, SPVM police officers conducted 12 interventions which required naloxone to be administered to individuals who had taken opioid overdoses. They acted as first responders across Montréal in different types of places.\nLives have been saved in a context where the number of deadly opioid overdoses recorded by the SPVM more than doubled in 2020, amounting to 65 compared to 28 in 2019. This was a first for the SPVM: at the time, no medication had yet been added to police officers’ work tools.", "pred_label": "__label__POS", "pred_score_pos": 0.8418896794319153} +{"content": "Laser beam expanders increase the diameter of a collimated input beam to a larger collimated output beam for applications such as laser scanning, interferometry, and remote sensing. Contemporary laser beam expanders are afocal systems developed from well-established optical telescope fundamentals. In such systems, the object rays enter parallel to the optical axis of the internal optics and exit parallel to them. This means that the entire system does not have a focal length.\nOptical telescopes, traditionally used to view distant objects such as celestial bodies in outer space, are divided into two types: refracting and reflecting. Refracting telescopes utilize lenses to refract, or bend, light, while reflecting telescopes utilize mirrors to reflect light.\nThere are two categories of refracting telescopes: Keplerian and Galilean. A Keplerian telescope consists of lenses with positive focal lengths separated by the sum of their focal lengths (Figure 1). The lens closest to the object being viewed, or source image, is called the objective lens, while the lens closest to the eye, or image created, is called the image lens.", "pred_label": "__label__POS", "pred_score_pos": 0.5448232293128967} +{"content": "Discover our 11 fault mitigation patterns\nHardware Fault Attacks are extremely powerful and have a high probability of success. In this paper, Riscure proposes 11 fault mitigation patterns, which are organized into three categories: Resist, Recover, and Respond. The first category increases code resistance to prevent disturbance of the program behavior. Recover patterns prevent insecure behavior after the fault took place. Lastly, to deter attackers of the fault Respond patterns are applied.\nFault Injection is a growing threat to devices and as the number of software vulnerabilities is raising, a systematic fault mitigation approach is necessary. As a leading security lab, Riscure has a long-standing experience and expertise in conducting Fault Injection testing and evaluation. Therefore, we are eager to share our knowledge on how to efficiently apply the patterns and protect the critical code by applying illustrative examples.\nPattern 1. FAULT.CONSTANT.CODING Problem:\nSensitive data carrying a limited set of values (like phase and state variables) is manipulated by fault injection attacks if they use trivial constant coding (e.g. 0, 1, 0xFF, or -1).\nSolution:\nDo not use trivial constants for sensitive data. These constants should use nontrivial values with the maximal hamming distance that is unlikely to be set through fault injection. This includes avoiding booleans which are coded in a trivial way (0 / 1). Use complex symbolic constants instead\nExample Constant Coding: int INITIALIZED = 0x5A5A; int AUTHENTICATED = 0x3EE3; Pattern 2. FAULT.RANDOM.DELAY Problem:\nAttackers aim to manipulate a specific value or decision.\nSolution:\nInsert random-length delays throughout code making it much harder to hit a specific moment in software execution.\nExample Random Delay:\nvoid delay () { // wait random time\nint loops = rand() & 0x3FF; // 10 bit entropy, 1024 possible values\nwhile (--loops >= 0 ) {\nloops++;\nloops--; // loop counter changes avoid compiler removal of non-functional loop\n}\n}\n3. Recover\nEven when fault injection is successful, it is possible to make resilient code that would continue correct execution and prevent exploitation. This includes double-checking to verify value correctness and crypto results, but also double-checking conditional statements, branches, loops, and program flow.\nPattern 3. FAULT.VALUE.CHECK Problem:\nSensitive data is manipulated by a fault injection attack at any time during program execution.\nSolution:\nVerify sensitive data. Sensitive data can, for instance, be protected by a checksum. Data protected in this way should be verified at regular intervals. Ideally, the integrity of sensitive data should be verified each time when used.\nExample Value Check:\nint result = SOME_VALUE; // sensitive value assigned\nint checksum = ~ SOME_VALUE; // use complement as checksum\nif (checksum == ~result) { // verify checksum //\ncontinue critical code execution\n}\nDo you want to read the other 8 fault mitigation patterns?\nThen download our white paper for free below.", "pred_label": "__label__POS", "pred_score_pos": 0.6059830188751221} +{"content": "Across the globe and spanning all industries, companies are recognising the need to leverage content marketing for business growth.\nSadly, many fail to get their audience to listen, understand, and care.\nBut – if done right – high-quality content is one of the best ways to showcase your expertise, connect with your audience, and build meaningful relationships.\nExplore our managed and done-for-you content marketing and copywriting services for innovative organisations who want to share their visionary ideas, gain leverage, and win their markets\nAt Tales, we understand the multiple facets of crafting effective brand content that optimally supports your business goals. Our data-driven approach will help you increase your traffic, convert leads, and make an impact.", "pred_label": "__label__POS", "pred_score_pos": 0.8926962614059448} +{"content": "Taste of the Wild PREY Angus Beef Recipe for Dogs is formulated to meet the nutritional levels established by the AAFCO Dog Food Nutrient Profiles for All Life Stages, including growth of large size dogs (31.81kg or more as an adult).\nPREY Angus Beef Recipe for Dogs features pasture-raised Angus beef as the first of just four key ingredients. Despite having limited ingredients, your dog won’t miss out on flavor or nutrition. Guaranteed probiotics help support digestion, while precise levels of vitamins and minerals, guaranteed antioxidants, omega fatty acids and DHA help ensure your dog gets the complete nutrition he or she needs, all with the rich, red-meat taste of beef dogs crave.\nAngus Beef – Angus Beef, the number one ingredient in this formula, is rich in nutrients and energy, and a highly digestible source of protein. Species Specific Probiotics – Healthy digestive and immune systems are vital to the overall health of your pet. Our proprietary K9 Strain Probiotics are developed specifically for dogs and added after the cooking process to ensure viability. Each pound of Taste of the Wild provides 80 million live, active cultures that help support healthy digestive and immune systems. Digestive Support – Fiber from garbanzo beans helps promote digestive health while prebiotic fiber from dried chicory root provides fuel for the beneficial probiotic bacteria in the digestive system. Antioxidants – Legumes and fruits, including peas, lentils, tomatoes, blueberries and raspberries, provide nutrients that help support your dog’s overall well-being while guaranteed levels of zinc, selenium and vitamin E support the immune system. Ingredients - Beef, lentils, tomato pomace, sunflower oil (preserved with mixed tocopherols), natural flavor, dicalcium phosphate, salmon oil (source of DHA), salt, DL-Methionine, choline chloride, taurine, L-Carnitine, dried Lactobacillus plantarum fermentation product, dried Bacillus subtilis fermentation product, dried Lactobacillus acidophilus fermentation product, dried Enterococcus faecium fermentation product, dried Bifidobacterium animalis fermentation product, vitamin E supplement, iron proteinate, zinc proteinate, copper proteinate, ferrous sulfate, zinc sulfate, copper sulfate, potassium iodide, thiamine mononitrate, manganese proteinate, manganous oxide, ascorbic acid, vitamin A supplement, biotin, niacin, calcium pantothenate, manganese sulfate, sodium selenite, pyridoxine hydrochloride, vitamin B12 supplement, riboflavin, vitamin D3 supplement, folic acid.\nContains a source of live (viable), naturally occurring microorganisms.\nAnalytical Constituents:\nGuaranteed Analysis % Crude Protein 27.0% Crude Fat 15.0% Crude Fibres 5.0% Moisture 10.0% DHA (Docosahexaenoic Acid) 0.05% minimum Zinc 150 mg/kg minimum Selenium 0.35 mg/kg minimum Taurine* 0.12% minimum Omega-6 Fatty Acids* 2.5% minimum Omega-3 Fatty Acids* 0.5% minimum Total Microorganisms*\n(Lactobacillus plantarum, Bacillus subtilis, Lactobacillus acidophilus, Enterococcus faecium, Bifidobacterium animalis)\nnot less than 36,363,636 CFU/kg\nAdditives per kg Vitamin A 15,000 IU/kg minimum Vitamin E 150 IU/kg minimum Calorie Content:\n3,719 kcal/kg (370 kcal/cup) Calculated Metabolizable Energy\nFeeding Guide: Standard Measuring Cups/Day\nPet Size 6 - 12 weeks 3 - 4 months 5 - 7 months 8 - 12 months Adult Dogs 1 - 2.25kg 75 - 125g 75 - 100g 66 - 100g 50 - 75g 50 - 66g 2.25 - 4.5kg 125 - 200g 100 - 175g 100 - 166g 75 - 133g 66 - 100g 4.5 - 9kg 200 - 325g 175 - 300g 166 - 275g 133 - 225g 100 - 175g 9 - 13.5kg 325 - 433g 300 - 400g 275 - 366g 225 - 300g 175 - 233g 13.5 - 18kg 433 - 550g 400 - 500g 366 - 450g 300 -366g 233 - 300g 18 - 27kg 550 - 750g 500 - 666g 450 - 625g 366 - 500g 300 - 400g 27 - 36kg 666 - 850g 625 - 766g 500 - 625g 400 - 500g 36 - 45kg 766 - 900g 625 - 725g 500 - 575g 45 - 57kg 700 - 825g 566 - 650g 575 - 675g 57 - 68kg 850 - 975g 675 - 775g 68 - 79kg 975 - 1050g 775 - 866g For adult dogs over 45.45kg, add 1/2 cup for every additional 4.54kg. For pregnant or nursing adult dogs, we recommend free-choice feeding. Adjust amount offered daily as needed to maintain ideal body condition. This feeding guide provides a starting point for the amount of food to give your dog each day. We recommend that you keep your dog in ideal body condition and not allow them to become overweight. The amount of food your dog needs can vary based on age, activity level or other food and treats given, so be sure to work with your veterinarian to determine an appropriate weight for your dog, and to make any necessary adjustments to their feeding. Changing Food: For 7 - 10 days, gradually decrease the amount of current food while increasing the amount of new food.\nAvailable Sizes:\n3.6kg, 11.3kg", "pred_label": "__label__POS", "pred_score_pos": 0.9230659008026123} +{"content": "A potential preventative measure is the natural sugar substitute, xylitol. Studies indicate that xylitol chewing gum, lozenges or syrup may reduce the occurrence of AOM by as much as 25%.\n[35] However, a study by Danhauer et al suggested that most parents are unaware that xylitol can prevent AOM and would be unlikely to use it in their preschool- and kindergarten-aged children. Nonetheless, the investigators, who employed an Internet questionnaire, did find that parents who were previously aware of xylitol as a preventive and who had children with a history of AOM would be more likely to give it to their youngsters. [36] What is the role of xylitol in the prevention of acute otitis media (AOM)? Author: John D Donaldson, MD, FRCSC, FACS; Chief Editor: Arlen D Meyers, MD, MBA more... Feedback", "pred_label": "__label__POS", "pred_score_pos": 0.9703739285469055} +{"content": "The memory-guided saccade task requires the remembrance of a peripheral target location, whilst inhibiting the urge to make a saccade ahead of an auditory cue. The literature has explored the endophenotypic deficits associated with differences in target laterality, but less is known about target amplitude. The data presented came from Crawford et al. (1995), employing a memory-guided saccade task among medicated and non-medicated patients with Schizophrenia (n=31, n=12), Bipolar Affective Disorder (n=12, n=17), and neurotypical controls (n=30). The cur-rent analyses explore the relationships between memory-guided saccades toward targets with different eccentricities (7.5 degs and 15degs), the discernible behaviour exhibited amongst diagnostic groups, and cohorts distinguished based on symptomatology. Saccade gain control and final eye position were reduced among medicated-schizophrenia patients. These metrics were lessened further among targets with greater amplitudes (15o), indicating greater deficit. The medicated cohort exhibited reduced gain control and final eye positions in both amplitudes compared to the non-medicated cohort, with deficits markedly observed in the furthest targets. No group differ-ences in symptomatology (positive and negative) were reported, however, greater deficit was ob-served toward the greatest amplitude. This suggests that within the memory-guided saccade paradigm, diagnostic classification is more prominent in characterising disparities in saccade performance than symptomatology.", "pred_label": "__label__POS", "pred_score_pos": 0.6347416043281555} +{"content": "Justice for the oppressed is close to God's heart. God is just, and calls us to be the same. This means treating people with the dignity with which God made them. It also means acting and speaking when others are denied their dignity. Even as we go about our daily lives, people the world over are enslaved, trafficked, and treated unfairly. Followers of Jesus must respond with grace, integrity, and urgency.\nTim Keller's\nprovides just the guidance we need. It treats a complex and, sometimes, controversial topic with the seriousness and nuance it deserves. Generous Justice Kellertackles tough topics in the Bible, where God's justice is called into questions. His answers are profound. And, he presents readers with a beautiful vision of what a justice that imitates the Just One can be. We heartily recommend giving it a read. It's a guide for our times.", "pred_label": "__label__POS", "pred_score_pos": 0.7351049184799194} +{"content": "This study is mainly concerned with sulfur isotope (delta S-34) values of inorganic sulfur species associated with the North Thrace Basin's coals (Saray and Pinarhisar coalfields). Sulfur isotope analyses were performed on pyritic sulfur, native sulfur, sulfate sulfur (rozenite) and the precipitated sulfate (P-BaSO4) (leached sulfate from the coal). The delta S-34 values of pyritic sulfur, rozenite, native sulfur and P-BaSO4 samples in Saray coals ranging from -6.9 parts per thousand to -37.3 parts per thousand are comparable to the delta S-34 values of Pinarhisar coals which change from -1.1 parts per thousand to - 59.3 parts per thousand. A wide range of strong negative delta S-34 values in both coalfields, particularly in Pinarhisar site, indicate that bacterial sulfate reduction (BSR) and subsequent pyrite formation were the key processes in the peat depositional environments. As in the delta S-34 values of both coalfield sites, comparable Sr/Ba and Th/U ratios and pyrite forms (cleat filling and partly massive) of the coals imply that besides marine sulfate hydrothermal solutions, originated from volcanism being active during peat accumulation in the basin, also contributed to the sulfur pools in the coal depositional environments.", "pred_label": "__label__POS", "pred_score_pos": 0.9866567254066467} +{"content": "CD8+ T cell effector function and transcriptional regulation during HIV pathogenesis Abstract\nA detailed understanding of the immune response to human immunodeficiency virus (HIV) infection is needed to inform prevention and therapeutic strategies that aim to contain the AIDS pandemic. The CD8+ Tcell response plays a critical role in controlling viral replication during HIV infection and will likely need to be a part of any vaccine approach. The qualitative feature of the CD8+ Tcell response most closely associated with immunologic control of HIV infection is its cytotoxic capacity. The pore-forming protein, perforin, is a major determinant of the cytotoxic capacity of CD8+ Tcells. In the context of chronic HIV infection, enhanced perforin expression by HIV-specific CD8+ Tcells is associated with greater control over HIV replication. However, individuals experiencing chronic progressive infection (CP) often demonstrate a diminished ability to express this important cytolytic molecule. HIV-specific CD8+ Tcells from CP also express lower levels of the T-box transcription factor T-bet, an upstream regulator of CD8+ Tcell effector differentiation and function. Whether HIV-specific CD8+ Tcells from progressors possess effector capacity during the earliest stages of infection and subsequently lose it remains unclear. The relationship between perforin, T-bet, and the closely related transcription factor eomesodermin (Eomes) also remains largely undefined in the context of acute, chronic, or controlled HIV infection. In this work, we report that CD8+ Tcell responses had high cytotoxic potential during acute HIV infection but perforin expression quickly waned with the resolution of peak viremia. Importantly, perforin was maintained in HIV-specific CD8+ Tcells with high levels of T-bet, but not necessarily in a population of T-betLo HIV-specific CD8 + T cells that expanded as infection progressed. During chronic infection there was a generalized increase in perforin expression for both total memory and HIV-specific CD8+ Tcells that was dissociated from both T-bet and Eomes. Of note, however, individuals in which perforin remained closely associated with T-bet demonstrated greater in vivo control of HIV replication. Collectively, our data imply that loss of transcriptional regulators responsible for driving strong cytotoxic responses, such as T-bet, contributes to CD8+ Tcell dysfunction during chronic progressive HIV infection.\nSubject Area\nVirology|Immunology\nRecommended Citation\nDemers, Korey R, \"CD8+ T cell effector function and transcriptional regulation during HIV pathogenesis\" (2016).\nDissertations available from ProQuest. AAI10194678. https://repository.upenn.edu/dissertations/AAI10194678", "pred_label": "__label__POS", "pred_score_pos": 0.6102174520492554} +{"content": "Abstract\nElevation in the intracellular Ca\n2+ concentration stimulates glucagon secretion from pancreatic α-cells. The Transient Receptor Potential Melastatin 4 channel (TRPM4) is critical for Ca 2+ signaling. However, its role in glucagon secreting α-cells has not been investigated. We identified TRPM4 gene expression and protein in the αTC1-6 cell line using RT-PCR and immunocytochemistry. Furthermore, we performed a detailed biophysical characterization of the channel using the patch-clamp technique to confirm that currents typical for TRPM4 were present in αTC1-6 cells. To investigate TRPM4 function, we generated a stable knockdown clone using shRNA and a lentiviral vector. Inhibition of TRPM4 significantly reduced the responses to different agonists during Ca 2+ imaging analysis with Fura-2AM. The reduction in the magnitude of Ca 2+ signals resulted in decreased glucagon secretion. These results suggested that depolarization by TRPM4 may play an important role in controlling glucagon secretion from α-cells and perhaps glucose homeostasis. Keywords α-Cells Ca signaling Glucagon secretion Pancreas TRPM4 ASJC Scopus subject areas Endocrinology Molecular Biology Biochemistry", "pred_label": "__label__POS", "pred_score_pos": 0.7833017110824585} +{"content": "Introduction\nThe selection of eligible candidates for a crisis negotiation team is one of the most crucial steps in preparing for mediation in a time of crisis. Therefore, it is important for organizations to consider key factors that should be taken into account. An ideal selection process should assess individual experience, personality, and technical abilities before deciding on the best fit for team members (Põlajeva, 2017). The following memorandum advertises open positions that will be required in the forthcoming negotiating team. It defines roles, responsibilities, and deliverables that members will fulfill as well as key factors and characteristics that will contribute to successful negotiations.\nMemorandum\nTo: All staff\nFrom: Project manager\nDate: September 04, 2018\nSubject: Crisis Negotiation Team\nFollowing the recent upsurge of crises in the organization’s internal and external environment, the management has decided to create a crisis negotiation team. This memo announces open negotiator positions that need to be filled.\nAccording to recent studies, estimated annual costs resulting from poor crisis management have risen tremendously in the 21\nst century. Our organization attests to this claim based on the last annual period in which we lost a significant amount of our profits to crises. Crises are inevitable. Therefore, it is better to be prepared than to be surprised when they occur. We believe that a crisis negotiation team is the best strategy for achieving preparedness. Here are the required positions and their roles: Chief Negotiator\nThe chief negotiator is responsible for making unilateral decisions, speaking and leading the negotiation toward conclusions, and binding the agency in a contract. This team member holds the highest authority within the team. The chief negotiators must have a depth and breadth of negotiating experience and a personality that’s well suited for negotiation efforts. In addition, they must showcase negotiation skills, professionalism, excellent oral communication skills, analytical abilities, and knowledge of crises.\nSummarizer\nThe summarizer intently follows the argument, occasionally intervening at opportune times to slow the argument and allow the chief negotiator to think critically. Intervention in negotiation involves asking questions for clarifications and summarizing negotiations. The summarizer must demonstrate logic, discernment, and excellent oral communication skills.\nNote Taker\nThe role of the note taker is to write quality notes in the course of negotiation. This team members should remain silent during the negotiation process unless required to do otherwise. Since quality note-taking is essential in a negotiation table, this role requires a member who holds experience, analytical ability, and good written communication.\nTeam Members\nThe team member is a legal and technical specialist and does not necessarily engage in the negotiation directly. Their role is to clarify and understand the issue in light of their expertise. They are also required to carefully observe the other negotiating team to detect visual and verbal cues. Team members must be able to contribute to the negotiations according to their knowledge level significantly and must keep their emotions and opinions in check.\nGiven the complexity of the negotiation process, eligible candidates should familiarize themselves with major factors that contribute to success in negotiations. They are broadly grouped into the following categories:\nAuthority – Negotiators should have the authority to conclude the deal. Credibility – People that uphold honesty and sincerity, and are reliable and steady are better at negotiating. Information – Negotiations rely on facts, past data, figures, empirical data, and future trends. Therefore, negotiators should be knowledgeable about crises. Time – Negotiations cannot go on endlessly because of time constraints. However, parties should be patient since undue pressure is not desirable. Emotional control – Good negotiators are aware of emotional responses and should always respond to arguments with emotional maturity. Communication Skills – Negotiations involve the exchange of messages which necessitate good communication skills (McMains & Mullins, 2014). Individuals interested in filling the open roles are encouraged to apply through the organization’s website.\nThank you,\nProject Manager. Conclusion\nSelection of negotiators should be based on candidates’ experience and potential strengths that may contribute to the success of negations in the team (Nadler, Thompson, & Boven, 2003). Each member should possess the capacity to contribute to the goals of negotiation and gains a sense of achievement after a successful negotiation process. The success of each negotiation process relies heavily on the skills, abilities, and professionality of individual members of the negotiating team. Order Unique Answer Now", "pred_label": "__label__POS", "pred_score_pos": 0.5526131987571716} +{"content": "Abstract\nMixing is an essential manufacturing process in various industries. The processing procedure and final product quality depend on the homogeneity of mixing. Because it is difficult to evaluate mixing systems experimentally, the discrete element method is commonly employed. However, as the number of particles increases, this approach incurs huge computational costs. The coarse grain model offers a potential solution, but its applicability has not been widely demonstrated; this study aimed to elucidate the upper limit for applying the coarse grain model. To determine the appropriate simulation parameters, calibrations were performed by comparing the powder bed in experiments versus simulations. Various mixing processes were numerically evaluated, and the mixing characteristics were qualitatively consistent among all coarse-grained ratios. These mixing systems were also evaluated quantitatively based on Lacey's mixing index, which indicated that the upper limit of the coarse-grained ratio was five times. It is therefore important to secure a sufficient number of particles in each cell and to use an appropriate number of cells. This study clarified the upper application limit and criteria for the coarse grain model and verified the maximum coarse-grained ratio (five times). This approach can be used to determine the coarse-grained ratio and reduce computational costs.\nKeywords Coarse grain model Coarse-grained ratio Discrete element method Lacey's mixing index Mixing ASJC Scopus subject areas Chemical Engineering(all) Mechanics of Materials", "pred_label": "__label__POS", "pred_score_pos": 0.8451888561248779} +{"content": "This paper provides a good introduction to material selection in paper and pulp applications, specifically ‘Kraft’ digesters where materials are subject to aggressive conditions including contact with black and white liquers. Alloy S32550 (”2605”) was recommended for future digester fabrication given its superior performance over other alloys, including Alloy 2205 – supporting the use of Ferralium\n® in this application due to the similarity in specification.", "pred_label": "__label__POS", "pred_score_pos": 0.9980375170707703} +{"content": "It can be frustrating. You are already behind because you burnt your toast and had to start over, but now to top things off, you are stuck behind a big, slow, vibrantly yellow school bus. It can be tempting to speed past the lumbering giant. You might want to quickly dart by the mechanically raised stopped sign. Beware! Washington laws protect school buses and, more importantly, children from hazardous driving.\nPay attention to the white board now and remember the following rules for sharing the road with our bumblebee themed school support staff.\nMost importantly, be careful when seeking to pass by a school bus (from any direction) while the bus is stopped near children. Those flashing red lights are there for a reason. Children – at any moment – may dart across the road not thinking about the dangers of traffic. While bus drivers are trained to keep their head on a swivel, there is no stopping a car quickly travelling no matter the reaction time.\nSpecifically, RCW 46.61.370 provides guidance on overtaking or meeting a school bus and, sure enough, drivers must stop when reaching a stopped school bus and may not accelerate until the “school bus resumes motion or the visual signals are no longer activated.” No gunning it to pass the bus!\nWhat if the school bus is on a larger, multilane road? RCW 46.61.150 provides additional guidance. If you are travelling the same direction as the school bus, you must stop. However, drivers need not stop if – and only if – they are travelling in the opposite direction and there are either three or more marked traffic lanes or the street is divided into separate roadways.\nPolice do not even need to be present for drivers to get in trouble. Under RCW 46.61.372, if a school bus driver can sufficiently identify a car or driver that violates these laws, the school bus driver may complete a written report. The report is then provided to the police for investigation. If the police identify the driver, they can still be cited for violating the law based on the school bus driver’s information.\nSchool buses are an integral part of our education system and allow thousands of children every day to attend school. Getting stuck behind a bus that stops every few blocks can be frustrating. Instead of violating Washington law and perhaps endangering kids, leave your house or work five minutes earlier to hopefully avoid the bus schedule.\nIf you know someone injured in a motor vehicle collision, knowing Washington law will prepare you for the inevitable fight with the insurance company. At the law offices of Magnuson Lowell, PS, we work each day to push back against at fault drivers and insurance companies. Call today for a free consultation.", "pred_label": "__label__POS", "pred_score_pos": 0.6487546563148499} +{"content": "Your divorce may include taking ownership of your marital home so that you may continue living in it. As noted on the North Carolina Judicial Branch website, you must file a claim to divide your property fairly between you and your soon-to-be ex-spouse.\nIf you fail to claim an interest in owning your home after divorce, the court may not honor your wishes to keep it. By filing a claim, however, the court may distribute the assets acquired during your marriage. A judge may review whether 100% ownership of your home reflects fairness.\nHow may the court determine fairness?\nThe Tar Heel State’s laws generally do not recognize fairness as an equal or a 50-50 division. When an individual requests 100% ownership of a marital asset, a judge may review several factors. The length of a marriage, each spouse’s age and any health conditions may determine whether a judge awards an asset to one spouse.\nTo keep your home, the court may require showing that you earn enough income to afford it. If you request custody of your children and they will reside in the home, you may file a claim for financial support. The amount of an award may contribute to your ability to maintain the home after your divorce.\nHow may a mortgage change with divorce?\nIf your home currently has an outstanding mortgage, you may refinance it to take ownership. As noted by Bankrate.com, a new home loan may release an ex-spouse’s name from the note. He or she may no longer have responsibility for making payments.\nYour home’s equity may support your request to take ownership of it. When filing a claim with the court, a judge may, however, review your ability to afford the home. A lender may also consider the payments you expect to receive as court-ordered financial support from your ex-spouse.", "pred_label": "__label__POS", "pred_score_pos": 0.8624091148376465} +{"content": "A new study published on the medRxiv* pre-print server and currently undergoing peer-review aims to answer this question through whole blood transcriptomics of individuals with varying degrees of COVID-19 severity. Transcriptomics, done by RNA sequencing, gives insights into the genes expressed in a cell at a given time point. It gives an analysis of all RNA molecules within a cell, in this case, whole blood.", "pred_label": "__label__POS", "pred_score_pos": 0.9814297556877136} +{"content": "This publication provides an analysis of the State of School Feeding Worldwide in 2020. A report on the State of School Feeding Worldwide was first published by WFP in 2013.\nThis document provides programmatic guidance to help maintain essential preventative, promotive, and curative sexual and reproductive health (SRH) services in fragile and humanitarian settings during the COVID-19 epidemic threat and outbreak period; including general guidance, the continuation of\n“My Hero is You” is a book written for children around the world affected by the COVID-19 pandemic. “My Hero is You” should be read by a parent, caregiver or teacher alongside a child or a small group of children.\nThe purpose of this document is to provide clear and actionable guidance for safe operations through the prevention, early detection and control of COVID-19 in schools and other educational facilities.\nAs school closures due to COVID-19 impact the majority of learners, education systems deployed remote learning solutions. Motivation is a central to learning. This poster presents tips for teachers on what they can do to motivate learners in such times.\nAs schools have closed due to COVID-19, the majority of children are learning remotely. Motivating your children during remote learning is central to their success. Motivation means ensuring they are interested, involved and confident in their learning.\nIn these times of school closure owing to the COVID-19 crisis, learners more than ever need their teachers’ support and continuous engagement with them.", "pred_label": "__label__POS", "pred_score_pos": 0.6141533255577087} +{"content": "This week’s blog comes from Team TutorPro HQ, after attending a webinar called ‘6 Essentials of Empowered Learner Experiences’. This webinar was sponsored by LinkedIn’s eLearning Industry group.\nThey discussed the future of learning and after conducting a research program with 52 Learning leaders from 36 organizations, they asked what one word or phrase describes the future of organizational learning. These were the most frequent responses:\nThey shared that learners want curated learning journeys and personalization of learner experiences through intuitive learning technology. There was discussion about the phrase soft skills being rephrased as interpersonal skills. Diversity, Equality, and Inclusion is the number one course in top firms.\nThe new world of learner experience is now expected to be transformative with a shift from skills-focused to knowledge-driven training. A focus on the whole self-model, not an isolated role focused along with a broader more flexible, less rigid training path.\nThey shared the six essentials are:\nThe webinar was very interesting and informative.\nIf you are interested in learning more about the TutorPro solutions, and how we can help your business achieve these six essentials and empower learning experiences, we’d love to hear from you.", "pred_label": "__label__POS", "pred_score_pos": 0.7227141857147217} +{"content": "Fund selection plays a crucial role in portfolio construction. Once the asset allocation decision has been made, these individuals need to decide how they want to be exposed, be it through a mutual fund, investment trust or ETF.\nOver the years, ETFs are becoming an increasingly important part of any investors’ toolkit. This series will show how the key players across the fund selection space use ETFs in their portfolios while asking what more can be done by the ETF providers to help with this increasing adoption.\nNext in the hot seat is Weixu Yan, portfolio manager and head of ETF research at Close Brothers Asset Management. Yan joined Close Brothers following the acquisition of Fortune Asset Management in 2010. He runs a number of multi-asset portfolios at the firm.\nHow much of your portfolio is made-up of ETFs/index funds?\nAs the manager of the Close Tactical Select Passive fund range, my portfolio is made-up of over 90% ETFs/index funds.\nAs a firm, Close Brothers Asset Management has two fund ranges that sit alongside the Close Tactical Select Passive funds; the Close Managed funds and Close Portfolio funds.\nWhile these products primarily invest in active third party-funds and direct stocks respectively, ETFs/index funds are used for exposure in areas where the fund manager deems there is no potential to generate significant alpha.\nWhen did you start investing in ETFs?\nI have been investing in ETFs since October 2011. This is when the Close Tactical Select Passive funds launched and ETFs were used to provide exposure to certain asset classes.\nWhich asset classes do you tend to invest in through ETFs?\nDue to investing in multi-asset funds, I invest in all asset classes through ETFs. This includes equities, fixed income, absolute return/hedge fund-like strategies and commodities.\nWhich areas would you avoid?\nI would not necessarily avoid any areas for using ETFs as wrappers. This is because I am more focused on how well an ETF’s underlying index is constructed.\nUsing this process, I determine whether liquidity has been taken into account at a stock selection level, and whether there are constraints to limit a single stock position from becoming too large within an ETF.\nIf the index is not transparent and constraints are not clear or implemented correctly, we would avoid this type of investment. Examples would be a VIX, or other indices that do not have sufficient liquidity.\nWhat is your methodology for selecting ETFs?\nMy methodology for selecting ETFs starts with fully understanding the index it aims to track. Following this, I conduct further research to determine if the ETF provider is robust and able to efficiently track the index.\nIn the final stages of analysis, when comparing ETFs from different providers that aim to track the same index, I will take the bid/ask spread, AUM, OCF, performance and tracking error of the ETF into account.\nI do not have a strong preference when choosing between physical and synthetic instruments, as long as in-depth research has been conducted to understand both the total return swap (in the case of synthetic replication) and the stock lending policy (with respect to physical replication).\nDo you have an ETF provider preference?\nI evaluate and review all ETF providers on a regular basis. One of my requirements for providers is that they meet our due diligence standards. When selecting providers, of main concern is how much support the ETF business receives if it falls under a larger brand; is it a core part of their overall business strategy?\nIf it is an independent ETF provider, then we determine how well it is capitalised and where it is drawing its operational mid- and back-office support from. Generally, I invest with ETF providers that maintain conservative securities lending policies.\nWhat ETF products would you like to see more of?\nIt tends to be difficult to find the right fixed income and alternatives ETFs which are important to capture uncorrelated returns. I would like to see more innovative and ‘smart beta’ products within fixed income.\nFor alternatives, I would like to see more ETFs tracking risk premia, where there is an element of shorting the markets.\nAdditionally, an interesting investment opportunity could be a property and infrastructure ETF reflecting the underlying asset’s risk and return profile, rather than an equity profile.\nAny areas ETF providers could improve?\nETF education could definitely be improved across the industry, but the first step would be to generate more interest amongst financial advisers and ultimately investors.\nETFs are exciting and innovative products which can be extremely cost-effective for investors as part of their portfolios. Effectively getting this message across should be a priority for providers.\nExpert investors is a new series brought to you by ETF Stream where on a fortnightly basis we interview the key individuals from across the fund selection and research space about the ETF industry. To read the previous edition of Expert Investors with Justin Onuekwusi of Legal & General Investment Management (LGIM), click here.", "pred_label": "__label__POS", "pred_score_pos": 0.7168785333633423} +{"content": "Issues, Challenges and Opportunities addressed:\nLessons from Internet governance can and should be applied to complex supply chain security challenges. Different stakeholders must collaborate to ensure the integrity of supply chains and prevent the proliferation of malware or harmful back-doors that may cause disruption in the digital and/or physical world.", "pred_label": "__label__POS", "pred_score_pos": 0.709627628326416} +{"content": "Two-year impact of the Spanish smoking law on exposure to secondhand smoke: evidence of the failure of the 'Spanish model'.Tob Control. 2012 Jul; 21(4):407-11.TC OBJECTIVE\nStudies evaluating the long-term impact of smoking laws on secondhand smoke (SHS) exposure using airborne markers are scarce. This study aimed to assess the long-term impact of the Spanish smoking law on SHS levels, using a specific and objective marker.\nMETHODS\nFollow-up study, measuring vapour-phase nicotine levels before the implementation of the law and 6, 12 and 24 months after the initial assessment. A total of 443 samples were taken at baseline in eight different regions in offices in the public administration, private sector, universities and hospitality venues.\nRESULTS\nTwo years after the law was implemented, the nicotine concentration decreased by a minimum of 60% in public administration, university and private sector offices, as well as in venues where smoking was totally banned. However, nicotine levels significantly increased by 40% in hospitality venues allowing smoking. No significant differences were found in hospitality venues with areas for smokers and non-smokers or in pubs and discotheques.\nCONCLUSIONS\nTwo years after the smoking law came into force, levels of SHS exposure in the workplace were significantly lower than before the law was implemented. Importantly, however, SHS levels were even higher than before the law was implemented in venues still allowing smoking. The data obtained in this study clearly show that the 'Spanish model' is not protecting the health of hospitality workers and that a complete ban is required. Furthermore, this study highlights the importance of long-term monitoring of compliance with smoking laws over time.\nMeSH Pub Type(s) Language PubMed ID Citation Tobacco Control,vol. 21, no. 4, 2012, pp. 407-11. Tob Control. 2012;21(4):407-11. Tobacco Control, 21(4), 407-11. https://doi.org/10.1136/tc.2010.042275 Tob Control.2012;21(4):407-11. PubMed PMID: 21659449.", "pred_label": "__label__POS", "pred_score_pos": 0.9459897875785828} +{"content": "Gua sha aims to move energy, known as qi or chi, around the body. The treatment involves using a tool to rub the skin in long stoke applying enough pressure to create minor bruising.\nGua sha may help to break down scar tissue and connective tissue, improving movement in the joints. The treatment does not have any serious side effects but is not suitable for those with certain medical conditions.\nGua sha is the practice of using a tool to apply pressure and scrape the skin to relieve pain and tension. This action causes light bruising, which often appears as purple or red spots known as petechiae or sha.\nThe name gua sha — pronounced gwahshah — comes from the Chinese word for scraping. It may also be called skin scraping, spooning, or coining.\nAccording to traditional Chinese medicine, qi or chi is energy that flows through the body. Many people believe that a person’s qi must be balanced and flowing freely to ensure their health and wellbeing.\nPeople also believe that qi can become blocked, causing pain or tension in the muscles and joints. Gua sha aims to move this blocked energy to relieve aches or stiffness.\nTraditional East Asian medicine also views blood stasis or stagnation as a cause of pain and illness. Another aim of gua sha is to move pooled or stagnated blood to relieve symptoms.\nSome physiotherapists use a version of the technique known as instrument assisted soft tissue mobilization (IASTM). Using a tool instead of the hands during a massage allows a physiotherapist to apply more pressure.", "pred_label": "__label__POS", "pred_score_pos": 0.6570566892623901} +{"content": "Extracellular Matrix Regulates Fibroblast Heterogeneity and Tumorigenesis Abstract\nHeterogeneous activated fibroblasts that deposit and remodel extracellular matrix (ECM) comprise desmoplasia, a key regulator of tumor development. The divergent outcomes in response to varied therapies targeting intratumoral desmoplasia underscore the pressing need to delineate the intricate role of a heterogeneous stroma in tumorigenesis. Fibroblast activation protein (FAP) and alpha-smooth muscle actin (?SMA) identify distinct, yet overlapping, activated fibroblast subsets in myriad tumor types, fibrosis, and wound healing. FAP Hi reactive fibroblasts and αSMAHi myofibroblasts can exert divergent influences on tumor progression. However, the factors that drive this phenotypic heterogeneity and the unique functional roles of these distinct phenotypes are not yet understood. By comparing fibroblast activation on fibronectin- and collagen I-coated hydrogels of varying stiffness, I demonstrated that a convergence of ECM composition, elasticity, and TGF-β signaling governs activated fibroblast phenotypic heterogeneity. Furthermore, by characterizing gene expression signatures, I revealed potentially unique roles of activated fibroblast subsets in tissue remodeling. In addition to its utility as a marker of activated fibroblasts, FAP also constitutes a highly attractive drug target due to its selective expression in the tumor microenvironment and its pro-tumorigenic proteolytic activity. FAP-mediated proteolysis of collagen I and III fragments promotes collagen clearance. However, the potential mechanistic link between FAP’s role in collagen proteolysis and tumorigenesis is not yet known. I investigated the role of FAP-dependent collagen proteolysis and ECM remodeling in tumorigenesis using both a spontaneous oncogenic Kras-driven lung tumor model and fibroblast-derived matrices. I found that Fap genetic deletion promotes intratumoral fibrillar collagen accumulation and attenuates lung tumor multiplicity, size, progression, and proliferation. Furthermore, I obtained preliminary evidence that Fap-/- lung fibroblasts produce ECM with enhanced fibrillar collagen accumulation, which directly impedes both tumor cell proliferation and motility. Taken together, my research underscores the essential role of ECM remodeling in regulating key aspects of tumorigenesis, such as intratumoral fibroblast heterogeneity, proliferation, and invasion.\nSubject Area\nCellular biology|Pharmacology|Oncology\nRecommended Citation\nAvery, Diana, \"Extracellular Matrix Regulates Fibroblast Heterogeneity and Tumorigenesis\" (2017).\nDissertations available from ProQuest. AAI10615798. https://repository.upenn.edu/dissertations/AAI10615798", "pred_label": "__label__POS", "pred_score_pos": 0.9992308616638184} +{"content": "Clyde & Co are delighted to invite you to join our webinar on “Reinsurance 101” on 18 November 2021, from 15:00 to 16:00 (HKT). Our Partners, Simon McConnell and Rosie Ng will discuss key legal issues in reinsurance.\nWhilst the current reinsurance market is continuing to assess the scale of its Casualty (natural catastrophe, cyber, PDBI) and Covid-19 exposure, current estimates place this figure in the region of US$100 billion. This has highlighted the importance of reinsurance capacity going forward. The transition to a sustainable future / ESG will present future opportunities for the reinsurance market not merely in terms of investment but also underwriting.\nIn the webinar we will focus on:", "pred_label": "__label__POS", "pred_score_pos": 0.9665269255638123} +{"content": "Compact2025 focal countries have made significant progress to reduce hunger and undernutrition. As reaffirmed in the recent roundtable discussions, strong national commitment buttressed by support from numerous partners and stakeholders has helped advance food security and nutrition in these countries. However, to meet their goals and end hunger and undernutrition by 2025, progress must be accelerated.\nEmerging from the recent Compact2025 roundtable discussions were several key recommendations for accelerating progress. These recommendations, as well as a way forward, are discussed in a synthesis of outcomes from the four roundtable discussions.\nWhile each country faces unique challenges to ending hunger and undernutrition, several cross-cutting recommendations for addressing challenges and exploiting opportunities to accelerate progress emerged in all four countries. These include\nMake strategies, policies, and programs more nutrition-driven Improve coordination and accountability Enhance and implement policies and scale-up successful programs Strengthen capacity Fill data and knowledge gaps\nAlong with recommendations that were common to the four countries, country-specific recommendations were put forth. In Bangladesh, empowering women will help achieve food security and nutrition goals while promoting gender equality. In Ethiopia, there is a need to develop policies and accountability for better nutrition. “Breaking the cycle” of food shortages met with humanitarian aid with holistic, transparent, and market-driven approaches is a critical recommendation for Malawi. Participants in the Rwanda roundtable discussion highlighted the crucial role for communications and advocacy for better nutritional outcomes.\nAs a way forward, Compact2025 aims to set up a Knowledge and Innovation Hub in each focal country, ideally within a high-level government office in partnership with relevant ministries and stakeholders. The hubs will work to support country goals, processes, and programs with demand-driven research and innovation for the purpose of accelerating progress. They will help to collect data, strengthen capacities, and enhance tracking and monitoring and evaluation systems.\nThe hubs will synthesize lessons and compile, share, and communicate information and best practices within and across focal countries. The country hubs will be supported by a global Knowledge and Innovation Hub that is currently in development.\nThe one-day roundtable discussions took place in Compact2025 focal countries Bangladesh (May 5, 2016), Ethiopia (March 28, 2016), Malawi (May 26, 2016), and Rwanda (March 24, 2016). The purpose of the meetings was to set the critical groundwork for assessing how to accelerate progress to end hunger and undernutrition in each country by 2025.\nFor more details on the roundtable discussions and documentation on each country’s current food security and nutrition situation, policy environment, and recommendations emerging from the roundtable discussions, see the blog posts for Bangladesh, Ethiopia, Malawi, and Rwanda.", "pred_label": "__label__POS", "pred_score_pos": 0.7563099265098572} +{"content": "It is true that the solutions that are offered in Affluenza are definitely useful. For instance, the solutions at political level that includes change of tax code to dishearten harmful consumption and decrease the need for the low income workers are most crucial in combating Affluenza because they are implemented by the authorities hence they will be followed by all people whether they like it or not. Those that are mentioned under societal level are also worthwhile. For example, simplicity groups are more efficient in helping individuals learn how to solve some of these problems.\nI totally agree that the solutions that the authors mention under personal level are actually less effective than those under political and societal levels. This is due to the fact that individuals when alone will tend to be unwilling in taking actions that are proposed under personal level. For example, it is true that the difference made after encouraging the households to use less air conditioning, drive less, use fluorescent light bulbs that are compact, recycle, among others is miniscule compared to discouraging sewage disposal, solid waste disposal, and emissions by a factory. I also believe that the ecological footprint that is associated with the process of recycling is huge.\nI agree that people are reluctant to engage in simple activities that can help to solve Affluenza malady. Many people have negative attitudes towards doing what is needed to treat this disease. It is also correct that individuals are deeply rooted to a common mindset that if there is no one else who is doing what is required to be done, they do not need to bother. I have personally witnessed some individuals who refuse to do the right thing just because others are not doing so. For instance, one of my friends declined to adopt a simpler lifestyle because no one in his family was ready to adopt this type of lifestyle.\nAffluenza is a convincing book hence I too believe that individuals who have gone through it may begin to change their consumption behavior. However, it will not be easy to convince those who have not read it. It is also completely true that despite the increase in awareness about causes and effects of global warming, ordinary people put in very little effort to relieve this condition. Individuals do not also put much effort in engaging in societal activities that are fundamental in solving our problems.", "pred_label": "__label__POS", "pred_score_pos": 0.5127218961715698} +{"content": "\"An erring conscience is an absurdity\": The later Kant on certainty, moral judgment and the infallibility of conscience Peer reviewed, Journal article Published version Permanent lenkehttps://hdl.handle.net/1956/21478 Utgivelsesdato2019 MetadataVis full innførsel Samlinger Department of Philosophy [187] Originalversjonhttps://doi.org/10.1515/agph-2019-1004 Sammendrag\nThis article explores Kant’s view, found in several passages in his late writings on moral philosophy, that the verdicts of conscience are infallible. We argue that Kant’s infallibility claim must be seen in the context of a major shift in Kant’s views on conscience that took place around 1790 and that has not yet been sufficiently appreciated in the literature. This shift led Kant to treat conscience as an exclusively second-order capacity which does not directly evaluate actions, but one’s first-order moral judgments and deliberation. On the basis of this novel interpretation, we develop a new defence of Kant’s infallibility claim that draws on Kant’s account of the characteristic features of specifically moral judgments.", "pred_label": "__label__POS", "pred_score_pos": 0.9207878708839417} +{"content": "Abstract\nIn Southeast Asia, the presence of cleared and burned forests has long evoked deep emotions, symbolism and representations that powerfully inform the governance of forests and upland peoples. In particular, the palpable visibility of shifting (swidden) agriculturalists ‘slashing and burning’ forests has fuelled centuries-old political agendas to criminalise swidden farmers for supposedly destroying swaths of forests valued for timber, biodiversity and now ecosystem services. Swidden farmers who regularly clear and burn forests, have endured a disproportionate burden of blame for investing in and maintaining an old livelihood practice into the 21st Century. Drawing on Hall’s politics of representation, we examine the contrasting political frames, management and practices of clearing and burning forests among upland farmers, state and non-state actors who govern forests on Palawan Island, the Philippines. We describe the social, economic, and biophysical character of swidden clearing and burning among the indigenous Tagbanua of central Palawan, whose livelihoods and landscapes are impacted by green governance and enclosures. Informed by several years of ethnographic fieldwork, we explore how and why Tagbanua farmers continue to clear and burn forest despite state and non-state actors criminalising these practices for decades. We argue that, despite sustained vilification and reduced fallows arising from governance policies and enclosures, Tagbanua farmers continue to clear and burn knowing well that, despite the practices being illegal, levels of tolerance and leniency toward swidden is the local norm, rather than exception—highlighting the importance of what we call ‘atmospheres of consent’. Ethnoecological understandings of clearing and burning in the uplands, we argue, are crucial to recalibrating the burden of blame placed on poor farmers whose agriculture is deemed destructive by the region’s burgeoning sustainability discourse.\nKeywords Criminalisation Ethnoecology Fire practices Philippines Resistant Swidden", "pred_label": "__label__POS", "pred_score_pos": 0.7200959920883179} +{"content": "If you're a Western fan of Indian food whose only experience of the cuisine is what's available in restaurants and ethnic markets, you're in for a treat. Kodampuli, sometimes spelled kudampuli, is a gateway ingredient to regional Indian cooking that doesn't get much attention in the U.S.: the cooking of Kerala in Southern India.\nWhat is Kodampuli?\nKodampuli (also known as gambodge, Malabar tamarind, fish tamarind, and mistakenly as kokum) is\na fruit used to add sourness to curries in Kerala. When the fruit ripens, it's removed from the vine, seeded, and left to dry in the sun till it turns leathery. The skins are then smoked, infusing them with a complex aroma: sweet, funky, and astringent.\nAfter a brief rinse and soak, the skins are added to curries, which in Kerala means a pungent sauce, rich with creamy coconut milk and abundant with the freshest seafood. Heat, time, and a bath of spices transform the kodampuli, allowing it to\ncontribute a pleasant sourness to the sauce, with hints of sweetness, astringency, and the faintest whiff of smoke. Kodampuli is what sourness tastes like in the absence of acidity. Its flavor isn't tart, and it doesn't brighten foods like acids do, but cuts through rich ingredients exceptionally well.\nThe effect on the dish is completely transformative—fish curry just wouldn't be the same without it. Much like white wine in or with a fish stew, kodampuli compliments fish's natural sweetness while giving it something to play against.\nHow Do I Use It?\nI wish I could say kodampuli is a versatile spice, but\nits use is almost exclusively restricted to Kerala cuisine, fish curry in particular. But don't let that keep you from getting your hands on some. Indian food, like Italian, French, and Chinese cooking, is intensely regional, and American restaurant diners are only exposed to a few regions' offerings. Kerala style cooking isn't among them, so if you want to expand your Indian food horizons, you'll need to do it on your own.\nKerala curries are refreshing. They don't rely on heavy amounts of liquid fat and avoid intense sweet spices like cardamom and clove. But they're satisfyingly meaty, not just from fresh fish (Kerala is on the water and is a thriving fishing hub), but from rich coconut milk, preferably chunky from bits of actual coconut (you can get frozen unprocessed coconut milk in Thai and Indian groceries). Kodampuli's sourness is a perfect balance to the rich coconut and intense spicing.\nUsing it is dead simple: Rinse it briefly to dislodge any grit, then soak it in hot water for a few minutes before adding it to any sauce. Three to four pieces is sufficient for a curry for four, and ten minutes' cooking is more than enough time for them to release their flavor.\nIn between your fish curry adventures, keep your kodampuli stored in as airtight containment as you can manage. It's got a strong odor that can contaminate other spices after prolonged exposure. Wrap it tightly in plastic, then put that in a large glass jar or an airtight plastic container. Keep it with your other sequestered-off spices, like asafoetida.\nWhere to Find Kodampuli\nKodampuli isn't easy to find. Well-stocked Indian groceries may carry it (Kalustyan's carries it for New Yorkers). If you can't find it locally, don't hesitate to seek it out online.", "pred_label": "__label__POS", "pred_score_pos": 0.6849666833877563} +{"content": "Legal narratives obtained from forensic interviews of twenty sexually abused children were analyzed concerning gender differences in disclosure patterns and narrative elaboration. Quantitative analysis of the children's disclosure of sexual abuse revealed that boys made prompted disclosures to caretakers, primarily mothers. Girls more often made purposeful disclosures, and revealed the abuse to caretakers as well as other supportive individuals. Quantitative analysis of the children's forensic interviews revealed that girls provided more coherent, elaborate, structured, and contextually detailed narratives than boys did. Children's accounts of their disclosures were qualitatively analyzed. Results indicated that fear was the primary reason children delayed abuse disclosure. Qualitative analysis also found that the children's narratives revealed several common themes including themes of force and resistance. Implications for legal interventions on behalf of children and the effectiveness of abuse prevention programs were discussed.\nContributors\nCreated\n2011", "pred_label": "__label__POS", "pred_score_pos": 0.609119176864624} +{"content": "'Yoga or Pilates for Older Adults with Chronic Musculoskeletal Conditions?' by Laura Denham-Jones\nSPARC 2021 Poster No. 18\nExercise interventions for older adults play an important role in public health as people work into later years. While age can exacerbate musculoskeletal conditions, this can be mitigated with appropriate physical activity.\nYoga and Pilates are the top group exercise choices in the UK and particularly popular among women, who are more prone to experience chronic musculoskeletal conditions. Systematic reviews by the researcher found that both are safe, adaptable interventions for chronic musculoskeletal conditions in a >70% female sample, mean age 50+. Yoga was effective for osteoarthritis and neck pain, improving physical functioning for osteoarthritis and sarcopenia. Pilates was effective for back, neck, osteoarthritis, and osteoporosis pain. Back and neck patients showed significant functional and quality of life effects. Pilates had benefits over a broader range of outcomes than did yoga without specific modifications and neither was found superior to other exercise comparators. This suggests that preferences are not always linked to orthopaedic health outcomes, and a mixed methods approach might lead to a better understanding of what participants experience, and what is important to them, when exercising.The next phase is a survey of the 50+ population exploring exercise habits, motivators, barriers, and perceived benefits. Finally, a trial and subsequent focus group will compare yoga and Pilates interventions specifically designed for this age group. The aim is to determine best practice in delivery and the relative benefits of age-targeted Pilates and yoga classes, addressing the value of including these on class timetables in the yoga, Pilates, and fitness communities.", "pred_label": "__label__POS", "pred_score_pos": 0.8557061553001404} +{"content": "In children with recurrent AOM, adenoidectomy has demonstrated efficacy. However, determining which children will benefit from this treatment modality is not yet possible. Few pediatric otolaryngologists recommend adenoidectomy initially over tympanostomy tube placement alone, unless coexistent nasal symptoms are present. The procedure might be considered for older children who require replacement of their tympanostomy tubes. As additional information on the role of biofilm in the nasopharynx becomes available, the selection of candidates for adenoidectomy with or without tube placement is likely to improve.\nWhat is the role of adenoidectomy in the treatment of acute otitis media (AOM)?\nUpdated: Sep 25, 2019\nAuthor: John D Donaldson, MD, FRCSC, FACS; Chief Editor: Arlen D Meyers, MD, MBA more... Feedback", "pred_label": "__label__POS", "pred_score_pos": 0.9836412072181702} +{"content": "Diversity and inclusion (D&I) strategies have simply not moved the needle for corporations. While a variety of factors, including inadequate resources, competing priorities, and lack of accountability, have all contributed to slow progress, changing demographics, the need for innovation, and globalization have made D&I more important than ever. It’s time to rethink traditional approaches. A complex issue that necessitates an integrated solution, D&I can be enhanced through mindfulness, which focuses on training the mind to balance the sometimes-competing functions of awareness and attention. Hallmarks of mindfulness include the ability to suspend emotional judgment under stress, greater self-awareness, and increased compassion in thought and action. By increasing competencies of presence, awareness, and attention, mindfulness at work can illuminate the behaviors and mindsets that build bridges across differences and enable organizations to leverage the power of D&I. Learning Objectives: - Examine the driving and restraining forces shaping D&I in companies today. - Understand how mindfulness increases the ability to pause and manage nonconscious biases in moments of communication and decision. - Discuss the advantages of increasing awareness, attention, presence, nonjudgment, and compassion in leadership and team behaviors to build more inclusive workplace cultures. - Discuss the advantages of developing mindfulness as a portable competency that enables employees to engage and contribute fully at work.", "pred_label": "__label__POS", "pred_score_pos": 0.9411665797233582} +{"content": "(RepublicanReport.org) – The US Supreme Court has attracted its share of negative attention this year. Liberal commentators are upset that the bench now contains six nominees from Republican presidents, compared to just three from Democrats. It looks as though the controversy will persist for the remainder of the year, as the 2021 SCOTUS docket has several divisive cases. Its new term begins on Monday, October 4.\nAbortion\nPerhaps the most controversial case before the nation’s highest court this year will relate to reproductive rights. In December, SCOTUS will consider a Mississippi case where the state government is trying to outlaw abortions after 15 weeks of pregnancy. If the court allows Mississippi to enforce this law, it will overturn the precedent set by the 1992 case of Planned Parenthood vs. Casey. This case provided that states cannot interfere excessively with a woman’s right to seek a termination before 22-24 weeks of pregnancy.\nIf the case succeeds, experts believe it could open the door for other states to introduce more restrictive laws around abortion.\nGun Control\nNext month, the court will also consider New York’s rules around concealed carry in public places. Lower courts have supported the current laws in the state, which require people to show they have a need to carry a weapon that’s greater than the need of the average person. Two Second Amendment advocates who could not obtain concealed carry licenses on this basis decided to challenge the law.\nNew York Attorney General Letitia James has insisted that the law is consistent with the Constitution, despite protests like the plaintiffs. However, legal experts believe the court’s current justices will take this opportunity to strengthen the Second Amendment.\nThe court will also hear a New Jersey case banning magazines with the capacity for more than ten rounds of ammunition. The court may wait until it decides in the New York case to begin considering this matter.\nReligious Liberty\nThis year, a Maine case coming before the court will look at whether the state government violates the Constitution by preventing students from attending schools that teach religion while benefiting from student-aid programs. This is the most significant First Amendment case that the three newest justices (all appointed by former President Donald Trump) will have dealt with. It will tell Americans much about how the court intends to approach religious liberties in the future.\nThere’s also been recent controversy over the idea that Justice Stephen Breyer should retire so that President Joe Biden and the Democrat-controlled Senate can replace him with a new liberal judge. Breyer, himself a noted liberal, has dismissed calls for his early retirement.\nIt looks like the country’s highest judicial power is set for an action-packed end to the year.\nCopyright 2021, RepublicanReport.org", "pred_label": "__label__POS", "pred_score_pos": 0.5808660984039307} +{"content": "The Impact of PNPLA3 rs738409 Genetic Polymorphism and Weight Gain ≥10 kg after Age 20 on Non-Alcoholic Fatty Liver Disease in Non-Obese Japanese Individuals.利用統計を見る\nFile / Name\nLicense\njournal.pone.0140427\nThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.\nNon-alcoholic fatty liver disease (NAFLD) in non-obese individuals is inadequately elucidated. We aim to investigate the impact of known genetic polymorphisms on NAFLD and the interaction between genetic risks and weight gain on NAFLD in obese and non-obese Japanese individuals. A total of 1164 participants who received health checkups were included. Participants with excessive alcohol consumption, with viral hepatitis or other inappropriate cases were excluded. Fatty liver was diagnosed by ultrasonography. Participants with a body mass index (BMI) of <18.5 kg/m2, 18.5-22.9 kg/m2, 23.0-24.9 kg/m2 and ≥25 kg/m2 were classified underweight, normal weight, overweight and obese, respectively. Self-administered questionnaire for lifestyle was assessed and a total of 8 previously reported genetic polymorphisms were chosen and examined. In all, 824 subjects were enrolled. The overall prevalence of NAFLD was 33.0%: 0% in underweight, 15.3% in normal weight, 41.1% in overweight and 71.7% in obese individuals. The prevalence of NAFLD is more affected by the G allele of patatin-like phospholipase domain-containing protein 3 (PNPLA3) rs738409 in normal weight (odds ratio (OR) 3.52; 95%-CI: 1.42-8.71; P = 0.0063) and in overweight individuals (OR 2.60; 95%-CI: 1.14-5.91; P = 0.0225) than in obese individuals (not significant). Moreover, the G allele of PNPLA3 rs738409 and weight gain ≥10 kg after age 20 had a joint effect on the risk of NAFLD in the normal weight (OR 12.00; 95% CI: 3.71-38.79; P = 3.3×10-5) and the overweight individuals (OR 13.40; 95% CI: 2.92-61.36; P = 0.0008). The G allele of PNPLA3 rs738409 is a prominent risk factor for NAFLD and the interaction between the PNPLA3 rs738409 and weight gain ≥10 kg after age 20 plays a crucial role in the pathogenesis of NAFLD, especially in non-obese Japanese individuals.", "pred_label": "__label__POS", "pred_score_pos": 0.9376915097236633} +{"content": "Abstract\nUncertainty remains on the threshold of ventilation rate in airborne transmission of SARS-CoV-2. We analyzed a COVID-19 outbreak in January 2020 in Hunan Province, China, involving an infected 24-year-old man, Mr. X, taking two subsequent buses, B1 and B2, in the same afternoon. We investigated the possibility of airborne transmission and the ventilation conditions for its occurrence. The ventilation rates on the buses were measured using a tracer-concentration decay method with the original driver on the original route. We measured and calculated the spread of the exhaled virus-laden droplet tracer from the suspected index case. Ten additional passengers were found to be infected, with seven of them (including one asymptomatic) on B1 and two on B2 when Mr. X was present, and one passenger infected on the subsequent B1 trip. B1 and B2 had time-averaged ventilation rates of approximately 1.7 and 3.2 L/s per person, respectively. The difference in ventilation rates and exposure time could explain why B1 had a higher attack rate than B2. Airborne transmission due to poor ventilation below 3.2 L/s played a role in this two-bus outbreak of COVID-19.", "pred_label": "__label__POS", "pred_score_pos": 0.9895420670509338} +{"content": "AMAZON FIRES POSE SERIOUS HEALTH RISK FOR COVID-19 AFFECTED COMMUNITIES\n06/22/2020\nScientists warn that people living in tropical regions from Brazil to Indonesia may face a heightened risk for COVID-19 complications due to particulate matter released from forest fires (Reuters, Reuters). Forest fires tend to peak from August to October in the Brazilian Amazon, while the forest fire season in Indonesia runs from April to October (Reuters). Experts caution that these fires will especially hurt populations already experiencing high rates of COVID-19, including Indigenous and Amazonian communities in the city of Manaus, Brazil, and Colombia’s Amazonas province (Reuters).\nEnvironmental enforcement in the Amazon has decreased since 2019, accelerating deforestation and raising the public health risk of forest fires (New York Times). Forest fires do not occur naturally in tropical biomes; rather, newly deforested areas are typically set on fire during drier months to prepare the land for cattle grazing. Researchers from the Amazon Conservation Association have already discovered the first fires of 2020 several months ahead of the season’s expected peak in August and September (Mongabay). According to a Brazilian government agency, deforestation in the Amazon rose 55% from January to April compared to last year. Meanwhile, coronavirus has killed 34,000 people in Brazil, which currently has the highest daily number of deaths in the world (New York Times).\nAne Alencar, the director of science at the think tank Ipam Amazônia, cites lack of environmental enforcement during the pandemic as a leading cause of increased deforestation and fire risk (New York Times). Alencar and other scientists have called for businesses and consumers who consume beef, leather, soy, and other Brazilian commodities to pressure Brazil to take action (Reuters).", "pred_label": "__label__POS", "pred_score_pos": 0.8074749708175659} +{"content": "Aurora kinases, which have been implicated in several vital events in mitosis, represent a protein kinase family highly conserved during evolution. The activity of Aurora kinases is delicately regulated, mainly by phosphorylation and degradation. Deregulation of Aurora kinase activity can result in mitotic abnormality and genetic instability, leading to defects in centrosome function, spindle assembly, chromosome alignment, and cytokinesis. Both the expression level and the kinase activity of Aurora kinases are found to be up-regulated in many human cancers, indicating that these kinases might serve as useful targets for the development of anticancer drugs. This review focuses on recent progress on the roles of Aurora kinases in mitosis and tumorigenesis.", "pred_label": "__label__POS", "pred_score_pos": 0.8629485964775085} +{"content": "Ransomware as a service (RaaS) equips prospective attackers, even those who possess minimal technical skills and knowledge, with the ammunition they need to launch attacks. This in turn helps ransomware spread quickly to more targets. What exactly is RaaS, and which ransomware families and techniques are associated with it?\nRansomware-stricken organizations grapple with multilevel extortion schemes that are advancing at an alarming rate. What exactly happens in these campaigns? We scrutinize three active ransomware families associated with these schemes to find out.\nModern ransomware like Nefilim present new challenges and security concerns for enterprises across the world. How do these new families differ from traditional ransomware? And what can organizations do to mitigate risks?\nThese tools were intended for use in security research and other authorized purposes. However, cybercriminals have found a way to exploit them for ransomware campaigns. What are some of these tools and how exactly are they weaponized?\nThe upheavals of 2020 challenged the limits of organizations and users, and provided openings for malicious actors. A robust cybersecurity posture can help equip enterprises and individuals amid a continuously changing threat landscape.\nRansomware continues the trend of targeted attacks but with the added challenge of double extortion. Organizations need to be one step ahead of such coercive tactics to avoid potential disruptions, financial losses, and reputational damage.", "pred_label": "__label__POS", "pred_score_pos": 0.9724873900413513} +{"content": "Mini-splits are convenient and versatile heating and cooling products. If you need to install a new HVAC system in your home, they could be the best solutions. Here’s everything you need to know about these innovative devices to determine whether they’re right for your needs.\nHow Do They Work?\nA mini-split features an outdoor condenser or compressor and multiple indoor air-handling units. Each indoor unit is placed inside the room or rooms that need to be treated. The indoor and outdoor parts are connected via refrigerant lines, eliminating the need for ductwork, which central air relies on.\nIn cooling mode, the system collects warm indoor air and transports it outside to the condenser via hidden pipes. The air moves through coils, transferring energy to the refrigerant and converting it into a gaseous state. This gas moves to the compressor, and the system uses electricity to turn it back into a liquid. At this stage, the previously warm air is cool and sent back into the air-handler, which distributes it throughout the room. The reverse occurs in heating mode, with the device creating warmth from ambient air outdoors and sending it into the house.\nWhat are the benefits?\nMini-splits are well-suited for homes that don’t have existing ductwork. Not only can ductwork installation be expensive, but the system can also lead to considerable energy loss. Since they require no ducts, these devices are cost-effective and energy-efficient. This means they’re also ideal for garages, attics, room additions, and other spaces where ducts can’t be installed.\nMini-splits are also simple to control. While there are buttons directly on the indoor units, most products have remotes so you can set the perfect temperature from anywhere in the room.\nPlus, since each area has its own unit, you can save energy by keeping it cooler or warmer as needed. For example, you might turn off climate control in bedrooms during the day when people are at work and school, then turn them on in the evening, thus reducing the household’s daily energy consumption.", "pred_label": "__label__POS", "pred_score_pos": 0.5727108120918274} +{"content": "OR WAIT null SECS\nA study released in JAMA reveals a 25% increase in cannabis use in pregnant women during the pandemic in the United States.\nStudy findings published in the\nJournal of the American Medical Association revealed that there has been a 25% increase of cannabis use in early pregnancy since March of 2020. The study was conducted by Kaiser Permanente and evaluated 100,000 pregnancies in Northern California from 2019 to 2020.\nPrior to the pandemic, the study reveals that approximately 6.75% of pregnant women were cannabis users and this has risen to over 8.14% during the pandemic. Kelly Young-Wolff, PhD, MPH describes this increase possibly linked to increased trauma, anxiety, and depression during the pandemic.\nThe study looked at urine toxicology tests for cannabis from the first prenatal visit for 100,005 pregnancies from January 2019 to December 2020 for data. This trend draws concern due to the reported potential risks to babies such as birth weight being affected and possible neurodevelopmental issues.\n1\nDeborah Ansley, MD, regional medical director for Kaiser Permanente’s Early Start prenatal health programexplains, “We need to get the word out more effectively that cannabis is not a healthy choice during pregnancy.”\n1\nReference\n1. Cannabis use by pregnant women increased during pandemic. News Release. EurekAlert! https://www.eurekalert.org/news-releases/929586. Accessed September 27, 2021.", "pred_label": "__label__POS", "pred_score_pos": 0.9151666760444641} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis toolkit is designed to help state system planners from early childhood, Head Start, and schools create plans for a successful transition to kindergarten. It includes materials like a transition and alignment summit guide, a questionnaire on transition practices, and research and resources on why transition matters and how to engage families.\nThis website offers a variety of technical assistance activities and supports to build system capacity to improve outcomes for young children with disabilities and their families.\nThis collection of resources focuses on helping state administrators and program practitioners design and implement high-quality Out-of-School (OST) programs that support all students, including those with disabilities and special needs.\nThis website was designed by Maryland State Department of Education to support early childhood providers in promoting family engagement.\nThis step-by-step guide offers practical instructions on how to develop a local campaign to create a ballot initiative focused on providing a dedicated, sustainable stream of funding for early childhood, out-of-school time, violence prevention, and mental health programs.\nThis tool provides consumer information for what families should know about criminal background checks, including who should have a background check and what is included in state and federal requirements. It links to a state-by-state resource that provides information about licensing, about quality, and also the specifics on each state's criminal background check requirements.\nThis document provides links to teaching resources, training models, publications, and other resources to assist child care providers and families as they help children recover from exposure to a natural disaster or other traumatic event. It includes links to relevant federal agencies, national organizations, and additional publications.\nThe School-Age Consumer Education toolkit shares consumer education information, including state examples and resources, on the physical, social, and emotional health and development of school-age children and engagement efforts with their parents and families.\nThis list is an annotated collection of materials on suspension and expulsion. It includes a robust range of policy and research overviews, reports and articles, audiovisual sources, and online materials. While it is designed for early childhood through grade 3 in Vermont, most resources are relevant for older school-age and those beyond the state of Vermont.\nThis toolkit is designed to support states and territories in designing a policy approach to promote social emotional development and reduce the likelihood of expulsion and suspension.", "pred_label": "__label__POS", "pred_score_pos": 0.9498150944709778} +{"content": "This volume provides intimate anthropological accounts of Muslim men’s everyday lives in the Middle East, Asia, Africa, and diasporic communities in the West. Amid increasing political turmoil and economic precarity, Muslim men around the world are enacting nurturing roles as husbands, sons, fathers, and community members, thereby challenging broader systems of patriarchy and oppression. By focusing on the ways in which Muslim men care for those they love, this volume challenges stereotypes and showcases Muslim men’s humanity.", "pred_label": "__label__POS", "pred_score_pos": 0.9454944729804993} +{"content": "A cost-efficient, faster and secure cross-border payments system will boost international business, while ensuring that migrants aren’t charged exorbitant rates for sending money home and more people are included into the present financial system. The blockchain technology can make it all a reality.\nHow Blockchain Is Being Used To Solve Cross-Border Payments Problems\nIt has been nine years since Bitcoin came into existence, enabling fast, low-cost and transparent peer-to-peer transactions. Over these years, Bitcoin has seen both—glory and gloom. Today, it lives on and so does its underlying technology—blockchain—which has captivated various entities, especially financial institutions and banks. With the hope that the distinct advantages of Bitcoin can be replicated by imbibing the blockchain technology into their ecosystems, many monetary institutions have been exploring it.\nCross-Border Payments\nOver the last few decades, there has been a steady rise in global businesses and international trade along with diaspora contributing to an increase in intricate cross-border payments. Cross-border payments account for about 40% of global payments transactional revenues with payment flows of more than $135 trillion during 2016 (as per McKinsey).\nOne crucial limitation of the system is its inability to cater to the unbanked population (38% according to the World Bank data) as well as those residing in regions where Corresponding Banking Relations (CBRs) have been withdrawn (such as Caribbean region).\nBlockchain Solutions for cross border payment\nTo overcome the current structural weaknesses, financial institutions and banks are adopting blockchain to offer near instant cross-border payments at lower costs, higher security and more reliability. With blockchain, payments are tamper-proof and accurate, thereby trimming costs associated with investigation of cases and litigation.\nSince its launch in 2009, bitcoin has often captured headlines for the wrong reasons. Variously associated with criminal activity, theft, and a libertarian movement that focuses on disintermediating banks, it has generally been deemed inappropriate for mainstream financial services. Nonetheless, the average dollar-equivalent value of daily bitcoin transactions has risen steadily to $160 million in recent months, equivalent to 25% of global consumer-to-consumer remittance flows processed by MTOs (and larger than the daily volume processed by digital-only MTOs). Meanwhile, several technology startups have received substantial venture capital backing to launch pilot programs that offer cross-border payment services based on bitcoin transfers.\nSuccessful application of blockchain in the cross border payments\nAlign Commerce is a good example. It has leveraged the liquidity of bitcoin to local currency exchanges in strategic cross-border corridors to offer real-time, transparent, and low-cost cross-border payments to small and midsize enterprises. Its platform provides a unique visual dashboard that enables counterparties to track the progress of payment transfers with up-to-the-minute accuracy and implicit payment guarantees.\nAbra has followed the mobile “uberization” trend by offering peer-to-peer, real-time, cross-border payments via roving mobile tellers who can accept cash payments in exchange for instant-payment bitcoin transfers to any recipient with online or mobile access. And funds can be withdrawn from a similar mobile teller in the destination country such as a teller agent in the active corridor between the U.S. and the Philippines.\nIt is widely believed that over 90% of bitcoin’s daily transaction volume is generated by speculators, rather than by buyers of traditional goods and services. (The average value of daily exchange-traded volume is close to $30 million). However, the substantial volumes and endurance of bitcoin are prompting some to look more closely at its underlying technology and to explore how it might be used to more rapidly and securely execute and track transfers of value while creating an immutable audit trail.\nThe year 2017 started with SWIFT launching a Proof of Concept (PoC) to help banks that are challenged with monitoring and managing their international nostro accounts—crucial for streamlined cross-border payments. This is a part of SWIFT’s global payments innovation initiative that is looking to set new standards in cross-border payments.\nSWIFT, short for Society for Worldwide Interbank Financial Telecommunications, can be considered a synonym for international payments. To test and validate the PoC’s blockchain application, 22 additional banks joined the initiative in July 2017.", "pred_label": "__label__POS", "pred_score_pos": 0.9268587231636047} +{"content": "Abstract\nIntrahepatic portal-systemic shunts causing hepatic encephalopathy are very rare. This is a case report of a patient with hepatic metastases of a pancreatic islet cell tumor that manifested with transtumoral shunts leading to hepatic encephalopathy. The diagnosis was confirmed with Doppler ultrasound and initially treated with selective transhepatic portal vein embolization followed by hepatic artery embolization, and eventually radiofrequency ablation of the largest metastases. Despite excellent short-term palliation, symptom recurrence necessitated liver resection, the results of which proved durable. A multidisciplinary treatment plan for the identification and management of potentially salvageable encephalopathy in similar patients is described.\nOriginal language English (US) Pages (from-to) 4-7 Number of pages 4 Journal Hepato-Gastroenterology Volume 50 Issue number 49 State Published - Jan 1 2003 Keywords Encephalopathy Hepatic Metastases Portal-hepatic venous shunts", "pred_label": "__label__POS", "pred_score_pos": 0.6207355856895447} +{"content": "The Single Euro Payments Area (SEPA) is probably the most ambitious self-regulatory project aimed at creating a single integrated European digital payments market since the introduction of the Euro. SEPA aims to make EU more innovative and competitive. When considering the SEPA initiative and combining it with the disruptive and innovative nature the mobile phone permeates, the result is a market that is rapidly transforming from well-established into a state of flux. We build a model to understand and explain this transformation of the digital payment infrastructure. The model captures the formation and development of digital payment infrastructure with a particular emphasis on the regulator´s perspective. It consists of four stages characterized by slow incremental change following by short rapid bursts of discontinuity. Each stage is portrayed by its evolutionary dynamics, the nature of the payment platform, the legal implications, the regulatory asymmetry, the level of competition, and what drives the discontinuity.\nOriginalsprog Engelsk Udgivelsessted Frederiksberg Udgiver Department of IT Management. CBS Antal sider 17 ISBN (Trykt) 9788792524195 Status Udgivet - 2013\nNavn ITM Communications Nummer 2013/3 EU Digital payments SEPA Multi-sided platform Evolutionary economics Institutional isomorphism Regulation", "pred_label": "__label__POS", "pred_score_pos": 0.5562599897384644} +{"content": "You’ve heard the saying “an apple a day keeps the doctor away,” but what happens if you eat an apple before bed?\nApples are the edible fruit of a flowering tree known as\nMalus domestica. They contain an array of nutrients, including carbohydrates, fiber, antioxidants, vitamins, and minerals (1).\nThese iconic fruits make a great snack when hunger strikes, and they’re one of the most consumed fruits globally. That’s mainly due to their seasonal availability, but they’re also tasty and versatile (2, 3).\nThis article explores the potential benefits and downsides of eating apples before bed.\nBelow are the nutrition facts for a 3.5-ounce (100-gram) serving of raw, unpeeled apple (6):\nCalories: 52 Carbs: 13.8 grams Sugar: 10.4 grams Fiber: 2.4 grams Protein: 0.3 grams Fat: 0.2 grams VitaminC: 8% of the Daily Value (DV) Potassium: 3% of the DV Magnesium: 1% of the DV Carbohydrates\nOne study showed that consuming a carb-rich meal with a high glycemic index (GI) before bed may raise tryptophan levels, which increases melatonin and serotonin. These hormones help promote the onset of sleep (8, 9).\nYet, other studies have found mixed results regarding the effects of high GI meals on sleep. Some studies show that a high GI meal can have no effect, while others report sleep disturbances (7, 9, 10).\nHigh GI foods can lead to a rapid increase in blood sugar...\nRead Full Story: https://www.healthline.com/nutrition/apple-before-bed\nYour content is great. However, if any of the content contained herein violates any rights of yours, including those of copyright, please contact us immediately by e-mail at media[@]kissrpr.com.", "pred_label": "__label__POS", "pred_score_pos": 0.7768025398254395} +{"content": "UBC Theses and Dissertations Predicting landslides using contour aligning convolutional neural networks Hajimoradlou, Ainaz Abstract\nLandslides are movement of soil and rock under the influence of gravity. They are common phenomena that cause significant human and economic losses every year. To reduce the impact of landslides, experts have developed tools to identify areas that are more likely to generate landslides. We propose a novel statistical approach for predicting landslides using deep convolutional networks. Using a standardized dataset of georeferenced images consisting of slope, elevation, land cover, lithology, rock age, and rock family as inputs, we deliver a landslide susceptibility map as output. We call our model a Locally Aligned Convolutional Neural Network, LACNN, as it follows the ground surface at multiple scales to predict possible landslide occurrence for a single point. To validate our method, we compare it to several baselines, including linear regression, a neural network, and a convolutional network, using log-likelihood error and Receiver Operating Characteristic curves on the test set. We show that our model performs better than the other proposed baselines, suggesting that such deep convolutional models are effective in heterogenous datasets for improving landslide susceptibility maps, which has the potential to reduce the human and economic cost of these events.\nItem Media Item Citations and Data License\nAttribution-NonCommercial-NoDerivatives 4.0 International", "pred_label": "__label__POS", "pred_score_pos": 0.9645401239395142} +{"content": "Nurturing talent will help companies survive the global COVID-19 pandemic, according to Peter Cappelli and Sydney Finkelstein.\nCappelli, a professor of management at The Wharton School at the University of Pennsylvania, and Finkelstein, a professor of management at the Tuck School of Business at Dartmouth College, recently recorded a podcast on superbosses.\nThe key, they said, is finding the best talent, then pushing them to continue learning and hitting goals.", "pred_label": "__label__POS", "pred_score_pos": 0.6181117296218872} +{"content": "Taste of the Wild PREY Trout Recipe for Dogs is formulated to meet the nutritional levels established by the AAFCO Dog Food Nutrient Profiles for All Life Stages, including growth of large size dogs (70 lbs. or more as an adult).\nWe believe everyone deserves to experience the benefits of simpler and cleaner eating. And that includes our pets. Limited ingredient diets may also be easier for some dogs to digest. In this simplified, limited ingredient recipe, spring-fed trout is the first of just four key ingredients. Along with sunflower oil, trout also provides omega fatty acids that help maintain skin and coat health. Species-specific probiotics further support digestion, while guaranteed levels of antioxidants and DHA help support overall well-being. Finally, carefully selected vitamins and minerals ensure your dog is getting the balanced nutrition they require with the unique taste of trout they’ll crave.\nTrout – Trout, the number one ingredient in this formula, is rich in nutrients and energy, and a highly digestible source of protein. Species Specific Probiotics – Healthy digestive and immune systems are vital to the overall health of your pet. Our proprietary K9 Strain Probiotics are developed specifically for dogs and added after the cooking process to ensure viability. Each pound of Taste of the Wild provides 80 million live, active cultures that help support healthy digestive and immune systems. Digestive Support – Fiber from garbanzo beans helps promote digestive health while prebiotic fiber from dried chicory root provides fuel for the beneficial probiotic bacteria in the digestive system. Ingredients - Trout, lentils, tomato pomace, sunflower oil (preserved with mixed tocopherols), natural flavor, dicalcium phosphate, calcium carbonate, salmon oil (source of DHA), salt, DL-Methionine, choline chloride, taurine, L-Carnitine, dried Lactobacillus plantarum fermentation product, dried Bacillus subtilis fermentation product, dried Lactobacillus acidophilus fermentation product, dried Enterococcus faecium fermentation product, dried Bifidobacterium animalis fermentation product, vitamin E supplement, iron proteinate, zinc proteinate, copper proteinate, ferrous sulfate, zinc sulfate, copper sulfate, potassium iodide, thiamine mononitrate, manganese proteinate, manganous oxide, ascorbic acid, vitamin A supplement, biotin, niacin, calcium pantothenate, manganese sulfate, sodium selenite, pyridoxine hydrochloride, vitamin B12 supplement, riboflavin, vitamin D3 supplement, folic acid.\nContains a source of live (viable), naturally occurring microorganisms.\nAnalytical Constituents:\nGuaranteed Analysis % Crude Protein 27.0% minimum Crude Fat 15.0% minimum Crude Fibres 5.0% maximum Moisture 10.0% maximum DHA (Docosahexaenoic Acid) 0.05% minimum Zinc 150 mg/kg minimum Selenium 0.35 mg/kg minimum Taurine 0.12% minimum Omega-6 Fatty Acids* 2.5% minimum Omega-3 Fatty Acids* 0.5% minimum Total Microorganisms*\n(Lactobacillus plantarum, Bacillus subtilis, Lactobacillus acidophilus, Enterococcus faecium, Bifidobacterium animalis)\nnot less than 36,363,636 CFU/kg\nAdditives per kg Vitamin A 15,000 IU/kg minimum Vitamin E 150 IU/kg minimum\n*Not recognized as an essential nutrient by the AAFCO Dog Food Nutrient Profiles.\nCalorie Content:\n3,592 kcal/kg (336 kcal/cup) Calculated Metabolizable Energy.\nFeeding Guide: Standard Measuring Cups/Day -\nPet Size 6 - 12 weeks 3 - 4 months 5 - 7 months 8 - 12 months Adult Dogs 1 - 2.25kg 75 - 125g 75 - 100g 66 - 100g 50 - 75g 50 - 66g 2.25 - 4.5kg 125 - 200g 100 - 175g 100 - 166g 75 - 133g 66 - 100g 4.5 - 9kg 200 - 325g 175 - 300g 166 - 275g 133 - 225g 100 - 175g 9 - 13.5kg 325 - 433g 300 - 400g 275 - 366g 225 - 300g 175 - 233g 13.5 - 18kg 433 - 550g 400 - 500g 366 - 450g 300 -366g 233 - 300g 18 - 27kg 550 - 750g 500 - 666g 450 - 625g 366 - 500g 300 - 400g 27 - 36kg 666 - 850g 625 - 766g 500 - 625g 400 - 500g 36 - 45kg 766 - 900g 625 - 725g 500 - 575g 45 - 57kg 700 - 825g 566 - 650g 575 - 675g 57 - 68kg 850 - 975g 675 - 775g 68 - 79kg 975 - 1050g 775 - 866g For adult dogs over 45.45kg, add 1/2 cup for every additional 4.54kg. For pregnant or nursing adult dogs, we recommend free-choice feeding. Adjust amount offered daily as needed to maintain ideal body condition. This feeding guide provides a starting point for the amount of food to give your dog each day. We recommend that you keep your dog in ideal body condition and not allow them to become overweight. The amount of food your dog needs can vary based on age, activity level or other food and treats given, so be sure to work with your veterinarian to determine an appropriate weight for your dog, and to make any necessary adjustments to their feeding. Changing Food: For 7 - 10 days, gradually decrease the amount of current food while increasing the amount of new food.\nAvailable Sizes:\n3.6kg, 11.3kg", "pred_label": "__label__POS", "pred_score_pos": 0.9332876205444336} +{"content": "The AASM has made a minor update to the Standards for Accreditation to clarify that only diagnoses\nbased upon the interpretation of a sleep study must be reviewed by an individual who is board-certified in sleep medicine (Standard F-8 of the Standards for Accreditation and Standard F-2 of the ). Independent Sleep Practice Standards for Accreditation\nMore substantial updates previously announced in 2016 emphasized safety, patient-centered care and long-term disease management. By\nJuly 1, 2017, all AASM-accredited facilities must show compliance with the updated 2016 standards by completing a reaccreditation application (if applicable) or submitting a signed attestation.", "pred_label": "__label__POS", "pred_score_pos": 0.8414523601531982} +{"content": "Policy field\nAntitrust\nTarget group\nAll citizens, companies, organisations and public authorities are welcome to contribute to this consultation.\nContributions are particularly sought from companies (including SMEs), business associations, public authorities, consumer organisations, as well as competition practitioners, researchers and think tanks. Comments from other stakeholders who have experience or knowledge of the enforcement of the EU competition rules by the national competition authorities are also welcome.\nConsultation period\nFrom\n04.11.2015 until 12.02.2016 Objective of the consultation\nThe European Commission is consulting stakeholders on how to empower the national competition authorities (NCAs) to be more effective enforcers.\nThe NCAs play a key role enforcing the EU antitrust rules alongside the Commission, but there is potential for them to do much more. While EU law (Regulation 1/2003) gave NCAs the competence to apply the EU competition rules, it did not tackle the means and instruments by which NCAs apply those rules. As a result, NCAs encounter difficulties in carrying out their work and in tapping their full potential.\nThe Commission would like to gather views on how to ensure that NCAs:\ncan act independently when enforcing EU competition rules and have the resources and staff needed to do their work;\nhave an adequate competition toolbox to detect and tackle infringements;\ncan impose effective fines on companies which break the rules; and\nhave leniency programmes, which encourage companies to come forward with evidence of illegal cartels, that work effectively across Europe.\nStakeholders are invited to answer those parts of the questionnaire which concern them and to provide any other comments or information which they consider to be relevant.\nView the questionnaire\nEUSurvey:\nConsultation questionnaire Reference documents and other related consultations Inception Impact Assessment Communication from the Commission - Ten Years of Antitrust Enforcement under Regulation 1/2003: Achievements and Future Perspectives (COM(2014) 453, 9.7.2014) Commission SWD \"Enhancing competition enforcement by the Member States' competition authorities: institutional and procedural issues\" accompanying the Communication from the Commission (SWD(2014 231 final) Communication from the Commission to the European Parliament and the Council, Report on the functioning of Regulation 1/2003 (COM(2009) 206 final, 29.4.2009) ECN Model Leniency Programme (MLP) Contact details\nResponsible service: Directorate-General for Competition – Unit A4 European Competition Network and Private Enforcement\nPlease always indicate the reference number in your correspondence: HT. 4504 email: COMP-ECNPLUS@ec.europa.eu Postal address: European Commission Directorate-General for Competition Antitrust registry Ref.: HT.4504 1049 Bruxelles / Brussels Belgique /België Fax (32-2) 295.01.28\nReplies to the consultation\nPublic authorities Austria - Federal Ministry of Science, Research and Economy and Ministry of Justice Belgium - Belgian Competition Authority Belgium - CCE Conseil Central de l'Economie - Commission de la Concurrence Croatia - Ministarstvo gospodarstva Czech Republic - Office for the Protection of Competition Denmark - Danish Competition and Consumer Authority and Danish Competition Council Estonia - Ministry of Justice Finland - The Finnish Competition and Consumer Authority France - Autorité de la Concurrence France - French Authorities Germany - Bundeskartellamt Iceland - Icelandic Competition Authority Ireland - Commission for Communications Regulation - ComReg Ireland - The Competition and Consumer Protection Commission (CCPC) Italy - Autorità Garante della Concorrenza e del Mercato Italy - Ministry of economic development Latvia - Ministry of Economics Latvia - Corruption Prevention and Combating Bureau Lithuania - Competition Council Lithuania - Ministry of Economy Netherlands - Ministry of Economic Affairs Portugal - Portuguese Competition Authority Romania - Competition Council Slovakia - Antimonopoly Office of the Slovak Republic Spain - Regional Service of Competition Protection Spain - Catalan Ombudsman Office (Síndic de Greuges de Catalunya) Sweden - Competition Authority United Kingdom - UK Government United Kingdom - CMA (Competition & Markets Authority) Registered organisations Austria - Industriellenvereinigung Austria - Wirtschaftskammer Austria - Bundesarbeitskammer Austria - Austrian working group of Studienvereinigung Kartellrecht Belgium - Independent Retail Europe Belgium - European Telecommunications Network Operators' Association (ETNO) Belgium - UEAPME Belgium - BEUC - The European Consumer Organisation Belgium - BusinessEurope Bulgaria - Bulgarian Chamber of Commerce and Industry Cyprus - Cyprus Chamber of Commerce and Industry Europe - NEON - The National Energy Ombudsman Network Europe - In-house Competition Lawyers' Association (ICLA) Finland - Roschier, Attorneys Ltd Finland - Confederation of Finnish Industries EK Finland - The Federation for Finnish Enterprises France - Fédération Nationale de l'Artisanat Automobile - F.N.A.A France - Groupe Eurotunnel France - AFEP - French Association of Large Companies France - Orange Germany - Der Mittelstandsverbund e.V. Germany - Handelsverband Deutschland (HDE) Germany - Bundesverband Paket und Expresslogistik e. V. (BIEK) Germany - United Internet AG Germany - EE&MC - European Economic & Marketing Consultants Germany - BDI Bundesverband der Deutschen Industrie International - Eversheds LLP Italy - ANIA - Associazione nazionale fra le imprese assicuratrici Italy - Altroconsumo Italy - Assonime Latvia - PricewaterhouseCoopers Legal (Latvia) Lithuania - Lithuanian Bar Association Lithuania - Lithuanian Free Market Institute Portugal - Abreu Avogados (Abreu & Associados – Sociedade de Advogados, R.L.) Romania - Asociatia pentru Protectia Consumatorilor din România Spain - UNESPA - Asociacion Española de Aseguradores Spain - Telefonica S.A. Spain - Repsol S.A. United States - American Chamber of Commerce to the EU (AmCham EU) Non-r egistered organisations Belgium - Free and Fair Post Initiative (FFPI) France - CLCV France - Association Française d’Etude de la Concurrence France - Collectif \"David contre Goliath\" Italy - Movimento Difesa del Cittadino Italy - Associazione Antitrust Italiana Portugal - Associação Portuguesa para a Defesa do Consumidor Slovenia - Slovene Consumers Association Spain - ASTEL Individual contributions Austria - Westbahn Management GmbH Belgium - G. van der Wal Bulgaria - Niveks Ltd Bulgaria - Hristov & Partners Law Firm Croatia - Gjurasic Fak & Partneri France - Alexandre Bertuzzi Greece - George Floras Ireland - Dr MaryCatherine Lucey Italy - Transporto Pubblico Non Dilinnea Latvia - Jelena Alfejeva Latvia - Glimstedt & Partners Law Firm Netherlands - P. Peereboom Spain - Iberdrola Spain - Asociación Española para la Defensa de la Competencia (AEDC) Sweden - Ann Margaret Nylen United Kingdom - MAD Promotion Records United Kingdom - Niamh Dunne United Kingdom - Pinsent Masons LLP United Kingdom - easyJet Airline Company Limited United Kingdom - Hogan Lovells International LLP United Kingdom - Vodafone Group Services Ltd Anonymous replies\n48 anonymous contributions", "pred_label": "__label__POS", "pred_score_pos": 0.5426571369171143} +{"content": "Is Child Pornography a State or Federal Law?\nChild pornography is any visual depiction of sexually explicit conduct involving a minor.\nUnder the Michigan Penal Code (750.145c), production, knowing possession, promotion, or distribution of any visual depictions of minors engaging in sexually explicit conduct could lead to a criminal charge.\nWith that said, the U.S. code also prohibits producing, knowing receipt, or distributing any child pornographic material. That means child pornography crimes can be prosecuted under state or federal law, depending on the underlying circumstances.\nWhatever the level of child pornography charges you may face, a child pornography offense can be life-altering, upon conviction, and require working with a skilled criminal defense attorney.\nIs Child Pornography a State or Federal Law?\nIf you face child pornography charges, this article provides all there is to know at the state and federal levels.\nState and Federal Child Pornography Crimes\nTypically, child pornography charges are prosecuted under state laws and are enforced by state law enforcement agencies.\nIf child pornography crimes cross state or international borders, or involve interstate or foreign commerce, federal law then comes into play.\nTherefore, it’s important to work with a lawyer well-versed in Michigan and federal law when facing any form of child pornography charges or sexual abuse charges.\nMichigan Child Pornography Laws – Penal Code (750.145c)\nMichigan law prohibits the production, distribution, and possesion of child pornography, as outlined below:\n1. Production of Child Pornography\nAny person who causes a child, in any way, to engage in sexually explicit conduct for the purpose of producing child pornography shall be guilty of a felony.\nIt’s important to note that taking photos of oneself as a minor or a minor encouraging another minor to take sexually explicit photos of themselves could result in the minors being charged with producing child pornography.\n*In Michigan a “child,” for purposes of the charge of production of child pornography, is under 18 years old.\nUnder Michigan law, the production of child pornography is punishable by a maximum of 20 years in prison, a fine not exceeding $100,000, or both. Additionally, asset forfeiture and repossession may also apply, depending on the case’s circumstances.\n2. Possession of Child Pornography\nUnder Michigan law, it’s a criminal offense for a person to have any form of child pornography in their possession. This includes personal photos shared among minors.\nFor example, a girl under 18 sending photos depicting sexually explicit conduct to her boyfriend could see him charged with possessing child pornography, upon arrest, with the images in their phone or any device.\nUpon conviction, possession of an image of child pornography carries a penalty of up to four years in prison, a fine of up to $10,000, or both. Additionally, asset forfeiture and repossession may also apply, depending on the circumstances.\n3. Distribution of Child Pornography\nUnder Michigan law, it’s a criminal offense for a person to participate in the distribution of child pornography.\nDistribution of child pornography offenses carries a penalty of up to 20 years in prison, a fine of up to $100,000, or both. Like other child pornography-related offenses, asset forfeiture and repossession may also apply, depending on the circumstances.\n4. Using the Computer or Internet to Commit a Crime\nBesides production, distribution, and possession of child sexually abusive material laws, the use of a computer or the internet is also applicable under child pornography rules where a computer, a computer network, or the internet was used in the violation of the crimes outlined above.\nPenalties for using a computer or the internet, in the commission of a crime, are dependent on the underlying offenses, which can range from between one year to a maximum of 20 years, a fine of between $5,000 and $20,000, or both, on top of other penalties for the underlying offenses.\nFEDERAL LAWS ON CHILD PRONOGRAPHY\nFederal child pornography laws are very stringent and carry severe penalties, compared to their state counterparts. They are designed to protect against sexual abuse of children and child sexual exploitation.\nWhat is Child Pornography Under Federal Law?\nWhile other images may be protected under first amendment rights, images of child pornography are not.\nUnder 18 U.S.C. 2256, any visual depiction of sexually explicit conduct involving a minor is classified as child pornography and illegal.\nVisual depictions include videos, photographs, computer-generated images that are indistinguishable from a minor, or any image that has been created to depict an identifiable minor.\nUnder federal law, underdeveloped film, videotape, and electronically stored data that can be processed into child pornography are also classified as child pornography.\nNotably, for an image to qualify as child pornography under federal law, there is no requirement that the child is depicted engaging in sexual activity. Any picture of a naked child may constitute child pornography if it’s sufficiently sexually suggestive.\nFederal Child Pornography Charges\nAs stated earlier, child pornography charges are prosecuted on a state level. However, under certain circumstances, federal law may come into play, which also means the involvement of federal law enforcement agencies.\nIt’s not uncommon for a charge to begin on a state level and then move up to a federal court as more evidence emerges, and vice versa.\nTherefore, having an attorney skilled at defending sexual crimes on a state and federal level is critical when facing child pornography charges, because you may never know how the evidence may play out in the future.\nCrimes committed using the internet across state and international lines may attract federal investigation and prosecution.\nCircumstances Under Which Federal Charges are Applicable\nBefore federal law enforcement agencies enforce federal child pornography laws, child pornography and child sexual abuse crimes must meet a specific criterion, according to 18 U.S.C. 2251 – Sexual exploitation of Children penal code.\nThe offense must have occurred in interstate or foreign commerce. For example, through the U.S. mail or carriers to move the child sexually explicit content across state lines or international boundaries.\nAdditionally, federal jurisdiction almost always applies where the internet was involved in committing child pornography-related crimes.\nThis law may still apply even where the image itself does not travel across state or national borders, if other materials, such as the computer or the storage devices, used to commit the offense did.\nFederal Child Pornography Laws on Production, Reception, Distribution, and Possessing Child Pornography\nFederal child pornography law prohibits the production, distribution, possession, and reception of child pornography through any means, including U.S. mail and interstate or foreign commerce (see 18 U.S.C. 2251; 18 U.S.C. 2252; 18 U.S.C. 2252a).\nSpecifically, federal child pornography 18 U.S.C. 2251a law on sexual exploitation of children, which covers causing a person below the age of 18 to engage in sexually explicit conduct to create images of child pornography, which includes any visual depiction of a child engaging in sexually explicit conduct and child sexual abuse, is a crime punishable by law.\nAdditionally, section 2251 of title 18 of the federal law on sexual exploitation of minors makes it a criminal offense for any parent or guardian, to a minor, to sell, buy, or transfer the minor’s custody for the purpose of engaging in sexually explicit conduct for the production of child pornography and sexual abuse.\nLastly, section 2256 of title 18 of the federal law prohibits the production, distribution, reception, transportation, shipping of images of child pornography, or any form of visual depiction of sexually explicit conduct uninvolving a minor by a person outside the United States and to transmit the child pornography to the U.S.\nFederal Child Pornography Law Penalties\nA violation of any federal child pornography law is a serious crime carrying severe penalties.\nWhen facing federal child pornography charges, it’s important to enlist the services of a skilled federal criminal defense attorney.\nUpon a conviction with child pornography 18 U.S.C. 2251 – sexual exploitation of children, an offender faces a minimum of 15 years in prison and a maximum of 30 years in prison.\nUpon violation of federal child pornography 18 U.S.C. 2252 law, the defendant faces a statutory minimum of five years in prison, with 20 years in prison being the maximum.\nSex Offender Registration for Child Pornography Offenses\nUpon a conviction with any child pornography offense, the offender is required by law to register with the Michigan sex offender registry, under the SORA act.\nBeing on the public sex offender registry can be life-altering and significantly affect the quality of your life.\nIt’s vital to ensure that you work only with the best sex crimes attorney, considering these consequences, to minimize the chances of a conviction.\nCan a Minor Receive Child Pornography Charges?\nWhile this issue is still legally controversial, it’s not unlikely for a minor to face child pornography charges, and the repercussions are often damaging to the child’s future.\nThere have been cases in the past where minors have faced child pornography charges. Most culprits, in such instances, are often high school students involved in sending explicit photos or videos of themselves to other minors, a crime commonly known as sexting.\nWhile sexting or sending such explicit content is considered legal among consenting adults, minors can now face charges under child pornography laws.\nIn other words, a minor who knowingly provides, offers, distributes, or sends a picture, photograph, video, film, or any visual depiction showing a minor engaging in sexually explicit conduct will risk severe penalties upon conviction.\nThat’s why it’s important to protect your teenager from prison time or sex offender registration by hiring a knowledgeable criminal defense attorney.\nDEFENDING YOUR CHILD PORNOGRAPHY CHARGES\nWhile child pornography, child sexual exploitation, or sexual abuse charges are serious and carry severe consequences, having a skilled attorney by your side can help you put up a good fight.\nYour skilled defense team can use a variety of defense strategies to fight your charges, which include:\nPossession of Three or Fewer Pornographic Images or Video\nSubsection (a)(4) and subsection (c) of U.S.C. 2252 provides an affirmative defense to mere possession of child pornography offense charge for persons with one image of child pornography or video, and a maximum of three.\nThis is a good strategy, especially if the defendant promptly notified law enforcement and took reasonable steps to destroy the material, without sharing it with anyone.\nNot Aware Victim was a Minor\nFor a conviction to happen, the prosecution must prove that the defendant knew or had reason to know that they were dealing with a minor’s image or video.\nIf your attorney can introduce reasonable doubt in your ability to have reasonably known that the image or video in question was a minor, you may be able to fight your charges.\nThis defense strategy is efficient where the victims depicted in the child sexually abusive material are fully grown in stature, and hard to tell that they are below the age of 18, from the depiction.\nLaw Enforcement Misconduct\nLaw enforcement officers obtain evidence for child pornography cases by searching your home or computer hard drives, in most circumstances. However, the police are only allowed to do that within the law.\nWhen evidence is illegally obtained, for example, without a search warrant or sufficient probable cause, your defense attorney can use police misconduct as a defense strategy to have your charges dropped, even when there is evidence to prove your child pornography offense.\nEither way, the outcome of your charges will largely depend on the quality of your defense.\nGet a Lawyer for Your Child Pornography Charges Today\nIf you face child pornography charges in Michigan, Nicole Blank Becker of Blank Law P.C. is the lawyer to call.\nNicole is a sex crimes defense attorney based in Michigan who has dedicated her practice solely to defending sex crimes charges.\nShe has over two decades of experience in child pornography charges, having done both Michigan and federal law, with a track record of success to back it up.\nYour future is dependent on the outcome of your charges. Don’t let your charges define your future.\nTo hire criminal defense attorney Nicole Blank Becker and have the best on your side, give us a call today or contact us online to book a free consultation.", "pred_label": "__label__POS", "pred_score_pos": 0.5171834230422974} +{"content": "UBC Theses and Dissertations Understanding academia's and educators' perception of arts-based research : using Superkids 2 documentary film as an example Guryil, Gizem Abstract\nArts-based research (ABR) has started to become more mainstream in recent years, leading to the increased adoption of documentaries by academics as a form of media-based research. While documentaries have intriguing potential to be utilized in research, there has been little research on how documentaries can also be a powerful tool for disseminating research. This project investigates the effectiveness, benefits, and challenges of constructing and disseminating knowledge through a research-based documentary. Using the documentary film Superkids 2 as an example, this study aims to explore academia’s and educators’ perception of arts-based research and investigate any changes of perceptions of gifted education. Employing an experimental design (i.e., one-shot case study), this study treated the screening of the Superkids 2 as an intervention. This study developed a survey to measure and develop a foundation for understanding academia’s perspective of arts-based research and examining the intervention’s effect after its implementation. Research participants included K-12 teachers, graduate students, and university researchers/lecturers/faculty members who participated in two major international conferences in gifted education. This study notes participants’ appreciation and desire to learn more about arts-based research along with concerns in conducting arts-based research. Funding and time are the main concerns about conducting arts-based research. The results contribute to the employability of arts-based research and research-based documentaries, which can lead to more prominent recognition of documentaries by the public. Findings also explore the changes in participants’ perception of gifted education.\nItem Media Item Citations and Data License\nAttribution-NonCommercial-NoDerivatives 4.0 International", "pred_label": "__label__POS", "pred_score_pos": 0.6429381966590881} +{"content": "Customized Risk Management Framework\nThis issue of\nThis issue of\nEngagement in Fragile and Conflict-Affected Situations presents a customized risk management framework to enhance ADB's effectiveness in fragile and conflict-affected situations.\nRisks to aid effectiveness can be exacerbated in countries experiencing fragile and conflict-affected situations (FCAS). There is no one-size-fits-all solution in FCAS, wherein standard business processes can be challenged by the need for flexibility and customized solutions.\nADB has committed to enhancing its effectiveness in FCAS with its 2007 Approach and its operational plan. One of the initiatives identified in the operational plan is the development of a customized risk management framework to guide ADB staff in managing risks in FCAS. The framework presents ADB’s existing business processes, which are customized in each phase of the project cycle to better address or mitigate the four major risks identified during the 2013 High-Level Forum on Building Resilience to Fragility in Asia and the Pacific.\nAdditional Details\nType Series Subjects SKU", "pred_label": "__label__POS", "pred_score_pos": 0.6734680533409119} +{"content": "LITTLE ROCK – Arkansas Attorney General Leslie Rutledge is warning the public about the dangers of cannabis edibles and hemp derivatives in packaging designed to look like well-known snack foods and candy. These products are unregulated, illegal and may be extremely dangerous. As Halloween approaches, parents should be aware that these look-alike products are being offered for sale online.\n\"The unregulated look-alike products are dangerous and marketed to kids and young adults and when consumed by a child can have 120 times the potency of the maximum legal adult serving,\" said Rutledge. \"If anyone sells these products to Arkansans I will hold them accountable to the fullest extent of the law. If you see these look-alike products for sale, report them to my office immediately.\"\nThese products may contain high concentrations of delta-9 tetrahydrocannabinol (THC), the psychoactive compound found in cannabis, and if eaten by children, can lead to an accidental overdose. According to the Department of Homeland Security, the most common overdose incidents among children involve ingestion of edible cannabis foods, and such overdoses are on the rise. In the first nine months of 2020, 80% of calls related to marijuana edibles to the Poison Control Center were for pediatric exposure. In the first half of 2021 alone, the American Association of Poison Control Centers reports poison control hotline calls have received an estimated 2,622 calls for services related to young children ingesting cannabis products.\nIf a child were to eat the entire bag, he or she would be consuming 120 times the maximum legal adult serving. Individuals and companies responsible for putting these edibles within the reach of children should carefully reconsider whether they choose to continue to profit from illegal look-alike cannabis edibles sales. Sellers may be subject to legal action and substantial civil penalties under the Arkansas Deceptive Trade Practices Act.\nLike any other drug, adults should take strong precautions to ensure that children do not have access to any products containing cannabis. Products advertising cannabis should not be purchased online through direct shipment platforms. Parents are encouraged to speak with their children, including young adults, and provide age-appropriate guidance about the dangers look-alike products pose.\nSymptoms of THC overdose include respiratory distress, loss of coordination, lethargy, and loss of consciousness. If you suspect your child has eaten a food containing high amounts of THC and become sick, call the Arkansas Poison Control Hotline at 1-800-222-1222. Consumers who encounter look-alike cannabis edible products are encouraged to file a consumer complaint with the Arkansas Attorney General's Office at (501) 682-2007 or [email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.6721618175506592} +{"content": "Paloma Health\nPaloma Health is a telehealth platform dedicated to the treatment of hypothyroidism. Through their online platform, you can access comprehensive hypothyroidism care from best-in-class endocrinologists and wellness experts.\nPeople with hypothyroidism produce a low amount of thyroid hormone; it’s most commonly experienced by women in mid-life. According to the North American Menopause Society (NAMS), hypothyroidism can mimic conditions associated with menopause transition — including fatigue, forgetfulness, mood swings, weight gain, irregular menstrual cycles, and cold intolerance.\nServices Provided: Treatment Type: Hormone Therapy Pharmaceutical (Non-Hormonal) Natural Supplements Lifestyle Changes Other Tags: Prescribed By Doctor Over the counter MMM Reviews:\nThis service provider has not been reviewed by the Menopause Made Modern team.", "pred_label": "__label__POS", "pred_score_pos": 0.6920694708824158} +{"content": "Hello, we have recently received reports that some accreditation auditors are not warranting non-compliance with Annex A substances, but rather that the relevant determination should be associated with the first 10 items of the standard. How are technical issues related? The accreditation inspectors claim that this is spoken by the IAF.\nDo the inspectors write the findings in the relevant Annex A as evidence, indicating the nonconformities they have identified from Annex A? For example, does the auditor specify \"A.9.4.4 by using the number 9.9.4, or by associating it with one of the first 10 items of the standard\" in relation to the use of privileged support programs?\nAnswer: We are unaware about IAF such related recommendations about ISO 27001 audits, but what I can tell you is that non-conformities statements must be as precise as possible, and if an auditor can state directly a control from ISO 27001 Annex A, then he should do it to make the understanding and resolution of the non-conformity easier.\nWhat is common is that, when applic able, the auditor states both controls from Annex A and requirements from the main sections of the standard. For example, non conformities related to control A.7.2.2 (Information security awareness, education and training) may also be associated to non compliance with requirement 7.2 Competence.", "pred_label": "__label__POS", "pred_score_pos": 0.6663515567779541} +{"content": "Abstract\nIn leaves, sucrose uptake kinetics involve high- and low-affinity components. A family of low- and high-affinity sucrose transporters (SUT) was identified. SUT1 serves as a high-affinity transporter essential for phloem loading and long-distance transport in solanaceous species. SUT4 is a low-affinity transporter with an expression pattern overlapping that of SUT1. Both SUT1 and SUT4 localize to enucleate sieve elements of tomato. New sucrose transporter-like proteins, named SUT2, from tomato and Arabidopsis contain extended cytoplasmic domains, thus structurally resembling the yeast sugar sensors SNF3 and RGT2. Features common to these sensors are low codon bias, environment of the start codon, low expression, and lack of detectable transport activity. In contrast to LeSUT1, which is induced during the sink-to-source transition of leaves, SUT2 is more highly expressed in sink than in source leaves and is inducible by sucrose. LeSUT2 protein colocalizes with the low- and high-affinity sucrose transporters in sieve elements of tomato petioles, indicating that multiple SUT mRNAs or proteins travel from companion cells to enucleate sieve elements. The SUT2 gene maps on chromosome V of potato and is linked to a major quantitative trait locus for tuber starch content and yield. Thus, the putative sugar SenSor identified colocalizes with two other sucrose transporters, differs from them in kinetic properties, and potentially regulates the relative activity of low- and high-affinity sucrose transport into sieve elements.", "pred_label": "__label__POS", "pred_score_pos": 0.9462236166000366} +{"content": "The miner who discovers the solution to a complex hashing puzzle first receives mining incentives, and the possibility that a participant will be the one to discover the solution is proportional to the network’s total mining power.\nA GPU (graphics processing unit) or an application-specific integrated circuit (ASIC) are required to set up a mining rig (ASIC).\nA New Gold Rush? A New Gold Rush?\nFor many miners, the possibility of being reimbursed in Bitcoin is the main draw. To be clear, you do not have to be a miner in order to own bitcoin tokens. You can also purchase cryptocurrencies using fiat money, exchange them for another cryptocurrency on an exchange such as Bitstamp (for example, using Ethereum or NEO to purchase Bitcoin), or earn them through purchasing, posting on services that pay users in cryptocurrency, or even opening cryptocurrency accounts that pay interest.\nSteemit is a cryptocurrency blog platform similar to Medium, with the exception that users can reward bloggers with STEEM, a proprietary cryptocurrency.\nThe Bitcoin reward that miners receive is an incentive that encourages people to contribute to the fundamental goal of mining: legitimizing and monitoring Bitcoin transactions to ensure their validity. Bitcoin is a “decentralized” cryptocurrency, meaning it does not rely on any central authority, such as a central bank or government, to monitor its regulation, because these functions are distributed among many users throughout the world.\nWhat exactly is Bitcoin mining? What exactly is Bitcoin mining?\nMine workers are compensated for their auditing services. They are in charge of determining if Bitcoin transactions are legitimate. Satoshi Nakamoto, the creator of Bitcoin, created this protocol to keep Bitcoin users honest. By confirming transactions, miners assist to prevent the “double-spending problem.”", "pred_label": "__label__POS", "pred_score_pos": 0.5214551687240601} +{"content": "We previously demonstrated that inhibition of Na-dependent phosphate (P(i)) transport in osteoclasts led to reduced ATP levels and diminished bone resorption. These findings suggested that Na/P(i) cotransporters in the osteoclast plasma membrane provide P(i) for ATP synthesis and that the osteoclast may utilize part of the P(i) released from bone resorption for this purpose. The present study was undertaken to define the cellular localization of Na/P(i) cotransporters in the mouse osteoclast and to identify the proteins with which they interact. Using glutathione S-transferase (GST) fusion constructs, we demonstrate that the type IIa Na/P(i) cotransporter (Npt2a) in osteoclast lysates interacts with the Na/H exchanger regulatory factor, NHERF-1, a PDZ protein that is essential for the regulation of various membrane transporters. In addition, NHERF-1 in osteoclast lysates interacts with Npt2a in spite of deletion of a putative PDZ-binding domain within the carboxy terminus of Npt2a. In contrast, deletion of the carboxy-terminal TRL amino acid motif of Npt2a significantly reduced its interaction with NHERF-1 in kidney lysates. Studies in osteoclasts transfected with green fluorescent protein-Npt2a constructs indicated that Npt2a colocalizes with NHERF-1 and actin at or near the plasma membrane of the osteoclast and associates with ezrin, a linker protein associated with the actin cytoskeleton, likely via NHERF-1. Furthermore, we demonstrate by RT/PCR of osteoclast RNA and in situ hybridization that the type III Na/P(i) cotransporter, PiT-1, is also expressed in mouse osteoclasts. To examine the cellular distribution of PiT-1, we infected mouse osteoclasts with a retroviral vector encoding PiT-1 fused to an epitope tag. PiT-1 colocalizes with actin and is present on the basolateral membrane of the polarized osteoclast, similar to that previously reported for Npt2a. Taken together, our data suggest that association of Npt2a with NHERF-1, ezrin, and actin, and of PiT-1 with actin, may be responsible for membrane sorting and regulation of these Na/P(i) cotransporters in the osteoclast.", "pred_label": "__label__POS", "pred_score_pos": 0.7855988144874573} +{"content": "dc.description.abstract The purpose of this grounded theory study was to explore the factors influencing college men’s positive masculinity development. This study conducted from a constructionist epistemological paradigm, through a queer theoretical lens, and using grounded theory methodology, resulted in the co-construction of a model of men’s positive masculinity development. Two semi-structured interviews conducted with eight undergraduate men provided an opportunity for participants to discuss their lives as men, their understanding of masculinity, the intersections of other aspects of their identity and their masculinity, and the role of peers, friends, family, and role models had on their development.The theory that emerged from this study is grounded in the participants’ experiences and depicts how sense of self, people, and life events influence positive masculinity development. Positive masculinity was influenced by a number of factors, but always through a lens of traditionally masculine norms. These norms were described as societal expectations traditionally ascribed to men. Lived experiences and interactions with family, role models, and friends who are women contributed to participant’s positive masculine ideals. Additionally, developing a strong sense of self and recognizing negative traits of their male peers also played a role in positive masculinity development. Positive masculinity was constructed not in opposition to hegemonic masculinity, but outside of traditional, binary constructions of masculinity. Furthermore, positive masculine conceptualizations influenced how the men considered their identity and their relationships with family, male peers, and women. This theory of factors of college men’s positive masculinity development has implications relevant for future theory development, understanding of gender construction, and student affairs practice.", "pred_label": "__label__POS", "pred_score_pos": 0.9773065447807312} +{"content": "Abstract Purpose\nCloud computing flexibility has advantages for IT professionals as well as non‐technical users. This paper aims to look at cloud computing from the library instruction perspective. The authors aim to discuss types of cloud computing applications for organizing information and sharing content, creating tutorials, collaboration, scheduling and storage. Additionally, the paper seeks to discuss types of applications used at ISU for library instruction and implications for teaching.\nDesign/methodology/approach\nThe authors conducted a literature review followed by practical applications of library instruction that included cloud‐computing technologies.\nFindings\nThe paper encourages library professionals to take advantage of cloud computing applications to provide better library instruction.\nOriginality/value\nThis paper offers insights on how cloud computing can be used for library instruction.\nKeywords Citation\nKoury, R. and Jardine, S.J. (2013), \"Library instruction in a cloud: perspectives from the trenches\",\nOCLC Systems & Services: International digital library perspectives, Vol. 29 No. 3, pp. 161-169. https://doi.org/10.1108/OCLC-01-2013-0001 Publisher:\nEmerald Group Publishing Limited\nCopyright © 2013, Emerald Group Publishing Limited", "pred_label": "__label__POS", "pred_score_pos": 0.9375460743904114} +{"content": "Results from a large study indicate that variants of the gene LRP5 are associated with a significant increase in the risk of fractures, by up to 20 percent, and lower levels of bone mineral density in the spine and hip, according to a study in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.", "pred_label": "__label__POS", "pred_score_pos": 0.9763981699943542} +{"content": "摘要:\n为了对中国特有的木本药用植物青钱柳进行优良种源和家系筛选和研究,分析了12个种源33个家系青钱柳的生长和黄酮积累。结果表明:种源间和种源内家系间均对树高和胸径生长的变异产生了显著的影响,但种源的影响更大;而总黄酮和黄酮单体(槲皮素、异槲皮苷、山奈酚)的含量仅在种源内家系间产生了显著的变异,家系的影响平均占到总变异的86%,而且生长和黄酮积累均表现出明显的地理变异规律。聚类分析结果表明,33个青钱柳家系可以划分为4类。\n关键词: 青钱柳 地理变异 生长 黄酮 种源家系\nDOI:10.13610/j.cnki.1672-352x.20171214.002\n投稿时间:2017-04-21\n基金项目:安徽农业大学稳定和引进人才项目(yj2016-03)资助。\nVariations in growth and flavonoid accumulation among different Cyclocarya paliurus provenances\nDENG Bo,HAN Yexin,LI Yuanyuan,ZHAO Zhuoqun\n(School of Forestry and Landscape Architecture, Anhui Agricultural University, Hefei 230036)\nAbstract:\nCyclocarya paliurus is a sole medicinal tree species in China. However, limited information is available on its genotype selection for improving growth and flavonoid production. In this study, we analyzed the growth and flavonoid accumulation in 33 families of Cyclocarya paliurus from 12 provenances. Results indicated that tree height and diameter at breast height growth were significantly influenced by provenance and family, while provenance had more important impact. The contents of total and individual flavonoids (quercetin, isoquercitrin, and kaempferol) were significantly influenced only by family, which accounted for 86% of total variation. The growth and flavonoid accumulation of C. paliurus showed a distinct geographic variation pattern. The hierarchical cluster analysis based on the growth and flavonoid contents in leaves indicated that 33 families of C. paliurus can be classified into 4 distinct groups.\nKey words: Cyclocarya paliurus geographic variation growth flavonoid provenance and family", "pred_label": "__label__POS", "pred_score_pos": 0.8788453936576843} +{"content": "Economic Report 2021 - OGUK\nECONOMIC REPORT 2021\nCommodity prices and markets Commodity prices have seen continued recovery from the low levels experienced during the pandemic, with Brent crude prices reaching $70/barrel by the end of August and gas prices touching 112 pence per therm (p/ th). Indeed, prices for the first half of 2021 have averaged 67.41p/th, one of the highest levels ever recorded. Oil: Despite the increase in prices, there is still uncertainty within the supply-demand dynamic as we continue to see subdued oil demand, below pre- pandemic levels, which is directly impacting the recovery in supply. Owing to reduced production, the market is reliant on OPEC+ countries to provide stability through continued production restrictions. The oil price collapse has constrained investment and greater confidence in long term pricing signals will help unlock investment in all types of energy resources including both greenfield and brownfield oil and gas projects. Such a recovery is still likely to be gradual, reflecting the range of pressures which companies continue to face.\nDespite falling demand, the UK remains reliant on imported coal to meet a supply gap from domestic production. Imports rose by 45 per cent in Q1 2021 compared with the same period in 2020 to fill the remaining demand gap largely within the industrial sector. Coal imports have supported most of the UK’s coal supply for the last decades, reaching a peak in 2013. The replacement of coal-fired generation with gas has been central to the UK cutting its carbon emissions by over 40 per cent since 1990. Continued access to gas generation alongside renewable power will be key to continuing to displace coal whilst ensuring ongoing security of supply. In this context, the UK has successfully avoided scenarios such as those seen currently in the EU, where coal-fired generation is increasing to supplement gas supplies constrained by production challenges. 4\n4 https://ec.europa.eu/energy/sites/default/files/quarterly_report_on_european_gas_markets_q1_2021_final.pdf\n12\nMade with FlippingBook - Online Brochure Maker", "pred_label": "__label__POS", "pred_score_pos": 0.9129073619842529} +{"content": "JavaScript is disabled for your browser. Some features of this site may not work without it.\nPerformance Pay and the White-Black Wage Gap\ndc.contributor.author Heywood, John S. dc.contributor.author Parent, Daniel dc.date.accessioned 2020-11-12T19:47:58Z dc.date.available 2020-11-12T19:47:58Z dc.date.issued 2009-08-01 dc.identifier.other 1259278 dc.identifier.uri https://hdl.handle.net/1813/73199 dc.description.abstract We show that the reported tendency for performance pay to be associated with greater wage inequality at the top of the earnings distribution applies only to white workers. This results in the white-black wage differential among those in performance pay jobs growing over the earnings distribution even as the same differential shrinks over the distribution for those not in performance pay jobs. We show this remains true even when examining suitable counterfactuals that hold observables constant between whites and blacks. We explore reasons behind our finding that performance pay is associated with greater racial earnings gaps at the top of the wage distribution focusing on the interactions between discrimination, unmeasured ability and selection. dc.language.iso en_US dc.subject performance pay dc.subject wage inequality dc.subject race dc.subject earnings dc.subject compensation dc.title Performance Pay and the White-Black Wage Gap dc.type preprint dc.description.legacydownloads cri_2010_017.pdf: 2071 downloads, before Oct. 1, 2020. local.authorAffiliation Heywood, John S.: University of Wisconsin - Milwaukee local.authorAffiliation Parent, Daniel: McGill University", "pred_label": "__label__POS", "pred_score_pos": 0.7991083860397339} +{"content": "© Copyright 2004 - 2009 Irish Medical Journal. This study examined victimisation, substance misuse, relationships, sexual activity, mental health difficulties and suicidal behaviour among adolescents with sexual orientation concerns in comparison to those without such concerns. 1112 Irish students (mean age 14yrs) in 17 mixed-gender secondary schools completed a self-report questionnaire with standardised scales and measures of psychosocial difficulties. 58 students (5%) reported having concerns regarding their sexual orientation. Compared with their peers, they had higher levels of mental health difficulties and a markedly-increased prevalence of attempted suicide (29% vs. 2%), physical assault (40% vs. 8%), sexual assault (16% vs. 1%) and substance misuse. Almost all those (90%) with sexual orientation concerns reported having had sex compared to just 4% of their peers. These results highlight the significant difficulties associated with sexual orientation concerns in adolescents in Ireland. Early and targeted interventions are essential to address their needs.", "pred_label": "__label__POS", "pred_score_pos": 0.8264850378036499} +{"content": "The Good Food Institute is a nonprofit working internationally to accelerate alternative protein innovation.\nGlobally, meat consumption is the highest it’s ever been. According to the UN, global meat production is projected to double by 2050.\nWith plant-based meat, cultivated meat, and fermentation, we can mitigate the environmental impact of our food system, decrease the risk of zoonotic disease, and ultimately feed more people with fewer resources.\nBy making meat from plants and cultivating meat from cells, we can modernize meat production.\nWe are developing the roadmap for a sustainable, secure, and just protein supply. We identify the most effective solutions, mobilize resources and talent, and empower partners across the food system to make alternative proteins accessible, affordable, and delicious.\nA world where alternative proteins are no longer alternative.", "pred_label": "__label__POS", "pred_score_pos": 0.6668041944503784} +{"content": "Abstract\nThis review and meta-analysis aim to assess the effect of prolonged progesterone support on pregnancy outcomes in women undergoing fresh embryo transfer after IVF/intracytoplasmic sperm injection (ICSI). Two independent authors searched Embase, MEDLINE and grey literature from inception to January 2019 for randomized controlled trials (RCT) of prolonged progesterone support versus early cessation. Risk of bias was assessed. Outcome measures were live birth, miscarriage and ongoing pregnancy rate. The study was registered with PROSPERO (CRD42018088605). Seven trials involving 1627 participants were included: three reported live birth rate (672/830), seven the miscarriage rate (178/1627) and seven the ongoing pregnancy rate (1351/1627). Clinical outcomes were similar between early progesterone cessation versus progesterone continuation: live birth rate (risk ratio [RR] 0.94, 95% confidence interval [CI] 0.88–1.00), miscarriage rate (RR 0.91, 95% CI 0.69–1.20) and ongoing pregnancy rate (RR 0.98, 95% CI 0.91–1.05). Ongoing pregnancy rates were similar when analyses were restricted to those with cessation of progesterone on the day of a positive human chorionic gonadotrophin (RR 0.93, 95% CI 0.83–1.06). This meta-analysis suggests that prolonged progesterone support may be unnecessary after fresh embryo transfer. Further larger RCT would be useful to corroborate and lead to standardized duration of progesterone luteal phase support across IVF/ICSI centres.\nKeywords IVF Live birth rate Luteal phase Miscarriage rate Ongoing pregnancy rate Progesterone", "pred_label": "__label__POS", "pred_score_pos": 0.9115932583808899} +{"content": "抄録\nWith the spread of Internet of Things (IoT), a lot of devices have been connected to networks. We believe that Open IoT, where devices are shared by multiple services, will be common in the future. However, constructing cyber-physical systems (CPS) by using shared devices has challenges. Since there are many combinations of devices and software in the network, designing and testing systems cannot be done manually as with current CPS. The system model and technologies suitable for Open IoT are necessary. In this article, we propose a new concept of CPS. It is 'Ephemeral-Cyber-Physical System (E-CPS),' which is temporarily constructed by combining devices in the network similar to an instance of cloud computing. Also, we propose a method of actuator control optimization for automatically constructing E-CPS by using nonconfigured devices connected to the network. This method will significantly contribute to not only E-CPS but also quick and inexpensive provision of conventional CPS. Experiments with a simulator, and with lighting devices and cameras confirmed that the method can automatically optimize the actuator control value and it enables satisfying the service requirements at a low cost.\nASJC Scopus subject areas 制御およびシステム工学 情報システム コンピュータ サイエンスの応用 コンピュータ ネットワークおよび通信 電子工学および電気工学", "pred_label": "__label__POS", "pred_score_pos": 0.9974926114082336} +{"content": "The ongoing global pandemic has led many people to pay less attention to their oral health and to skip their regular dental appointments. This could have disastrous effects on your teeth and gums, as well as your overall health.\nA recent study suggests that individuals with gum disease might be more likely to suffer severe complications of COVID-19. This stems from the connection between gum inflammation and the body’s inflammatory response.\nPeriodontal health evaluations from routine dental exams could be more crucial than ever. Dr. Michael Mulkey, a dentist in Marietta, GA, highlights the importance of seeking prompt treatment for gum disease.\nDo I Have Gum Disease?\nGum disease occurs when your mouth’s natural bacteria spreads and infects your gum tissue. The causation varies, but the condition requires intervention from a dental professional to treat.\nSome patients do not notice symptoms when they have periodontal disease, which emphasizes the importance of attending regular dental appointments every six months. Your dentist can evaluate your gum health and develop a treatment plan if necessary.\nOther dental patients may notice bleeding, sore, or swollen gums if they have periodontal issues. Though these symptoms may happen for acute reasons, you should contact your dentist if they continue.\nWhat Periodontal Treatment Will I Need?\nIf your dentist diagnoses you with gum disease, they will first clean your teeth and gums to remove excess plaque and bacteria. More extensive cleaning may be required to eliminate the infection. This technique is called scaling and root planing.\nIf the infection does not respond to this treatment, you may require laser or surgical solutions for targeted and intensive removal of damaged gum tissue. Dentists also emphasize preventative care for periodontal health. This includes practicing good oral hygiene habits, but they may also recommend rinsing with an antibacterial mouthwash to balance bacteria in your mouth.\nUntreated periodontal problems could lead to severe and irreversible dental issues such as tooth loss. If you have concerns about the health of your gums, schedule a consultation with your dentist as soon as possible.\nGet Prompt Treatment for Gum Disease in Marietta, GA\nLost Mountain Dental offers treatment for gum disease and many other dental concerns in patients in Marietta, GA. Dr. Mulkey specializes in general, cosmetic, and restorative dentistry, including implants and other tooth replacement solutions. To schedule an appointment with our practice, contact us online or reach our office by phone at 678.212.1280.", "pred_label": "__label__POS", "pred_score_pos": 0.8797797560691833} +{"content": "(2018)\nConspecifics inhabiting divergent environments frequently differ in morphology, physiology, and performance, but the interrelationships amongst traits and with Darwinian fitness remains poorly understood. We investigated population differentiation in morphology, metabolic rate, and swimming performance in three-spined sticklebacks (Gasterosteus aculeatus L.), contrasting a marine/ancestral population with two distinct freshwater morphotypes derived from it: the typical low-plated morph, and a unique small-plated morph. We test the hypothesis that similar to plate loss in other freshwater populations, reduction in lateral plate size also evolved in response to selection. Additionally, we test how morphology, physiology, and performance have evolved in concert as a response to differences in selection between marine and freshwater environments. We raised pure-bred second-generation fish originating from three populations and quantified their lateral plate coverage, burst- and critical swimming speeds, as well as standard and active metabolic rates. Using a multivariate Q(ST)-F-ST framework, we detected signals of directional selection on metabolic physiology and lateral plate coverage, notably demonstrating that selection is responsible for the reduction in lateral plate coverage in a small-plated stickleback population. We also uncovered signals of multivariate selection amongst all bivariate trait combinations except the two metrics of swimming performance. Divergence between the freshwater and marine populations exceeded neutral expectation in morphology and in most physiological and performance traits, indicating that adaptation to freshwater habitats has occurred, but through different combinations of traits in different populations. These results highlight both the complex interplay between morphology, physiology and performance in local adaptation, and a framework for their investigation.", "pred_label": "__label__POS", "pred_score_pos": 0.9605217576026917} +{"content": "Keywords:preference-based reinforcement learning, human-in-the-loop reinforcement learning, deep reinforcement learning, semi-supervised learning Abstract:Preference-based reinforcement learning (RL) has shown potential for teaching agents to perform the target tasks without a costly, pre-defined reward function by learning the reward with a supervisor’s preference between the two agent behaviors. However, preference-based learning often requires a large amount of human feedback, making it difficult to apply this approach to various applications. This data-efficiency problem, on the other hand, has been typically addressed by using unlabeled samples or data augmentation techniques in the context of supervised learning. Motivated by the recent success of these approaches, we present SURF, a semi-supervised reward learning framework that utilizes a large amount of unlabeled samples with data augmentation. In order to leverage unlabeled samples for reward learning, we infer pseudo-labels of the unlabeled samples based on the confidence of the preference predictor. To further improve the label-efficiency of reward learning, we introduce a new data augmentation that temporally crops consecutive subsequences from the original behaviors. Our experiments demonstrate that our approach significantly improves the feedback-efficiency of the state-of-the-art preference-based method on a variety of locomotion and robotic manipulation tasks. One-sentence Summary:We present SURF, a semi-supervised reward learning algorithm with data augmentation for feedback-efficient preference-based RL. Supplementary Material:zip\n0 Replies\nLoading", "pred_label": "__label__POS", "pred_score_pos": 0.8675446510314941} +{"content": "This paper explores the determinants of market diversification by export-oriented manufacturing firms using the logistic regression framework. The results show that firm level characteristics including age of the enterprise, managerial expertise, type of ownership, and size of the enterprise play a key role in determining the probability of market diversification by firms. These findings highlight the salience of firm level capacities in achieving export diversification in Pakistan. JEL Classification: F14, L25", "pred_label": "__label__POS", "pred_score_pos": 0.9855534434318542} +{"content": "International Literacy Day (ILD) 2021 is held on 8 September 2021 and this year’s theme is Literacy for a human-centred recovery: Narrowing the digital divide. It’s especially timely this year, as NSW students are learning from home. As UNESCO reports:\nThe COVID-19 crisis has disrupted the learning of children, young people and adults at an unprecedented scale. It has also magnified the pre-existing inequalities in access to meaningful literacy learning opportunities, disproportionally affecting 773 million non-literate young people and adults. Youth and adult literacy were absent in many initial national response plans, while numerous literacy programmes have been forced to halt their usual modes of operation. - from UNESCO’s official ILD page\nThis year the focus is on recovery of skills:\nILD 2021 will explore how literacy can contribute to building a solid foundation for a human-centred recovery, with a special focus on the interplay of literacy and digital skills required by non-literate youth and adults. It will also explore what makes technology-enabled literacy learning inclusive and meaningful to leave no one behind. By doing so, ILD2021 will be an opportunity to reimagine future literacy teaching and learning, within and beyond the context of the pandemic. - from UNESCO’s official ILD page\nHow can you support these ideas in the classroom?\nAs UNESCO posits, the recovery post-COVID lies in building literacy skills in students across the world. You could try some of the resources below in your classroom that may fit into your current programs of literacy learning or use them as a springboard into further literacy activities.", "pred_label": "__label__POS", "pred_score_pos": 0.777596652507782} +{"content": "Currently, the City of Vancouver’s Unlawful Camping Ordinance (Chapter 8.22 VMC) provides that it is unlawful for any person to camp or store personal property on any public land during daytime hours of 6:30 a.m. through 9:30 p.m.\nDespite this Ordinance, an estimated 500-600 individuals still reside in tents or vehicles within the City of Vancouver. This Council has observed that many individuals who camp on public property do so, not by choice, but due to a lack of financial means to afford adequate shelter. These individuals are adversely mentally and physically impacted by camping. Some people hold nighttime employment and cannot reasonably be expected to sleep during the hours allowed by VMC 8.22 (9:30 p.m. through 6:30 a.m.). Single female camp occupants experience a disproportionately high incidence of violent crime as compared to other people. Families with children who camp as a result of a lack adequate shelter are also disproportionately adversely impacted through risk of physical danger and impediments to childhood education.\nSimultaneously, Council has also observed that the City’s sensitive ecological areas are adversely impacted by adverse secondary impacts of camping. The City’s sensitive waterways, water treatment facilities, stormwater and wastewater facilities are particularly vulnerable to impacts of illegal dumping and improper disposal of human waste.\nThere are also Constitutional constraints on cities’ authority to regulate camping. The Ninth Circuit Court of Appeals has held that cities cannot criminalize camping in all places, at all times, unless there is adequate access to temporary shelter (Martin v. Boise). As a corollary to this holding, cities may impose 24-hour daily prohibitions against unlawful camping “in particular locations.” However, the City Attorney’s Office has advised that these locations should be no broader than necessary and Council should ensure that adequate public space remains for nighttime camping throughout the rest of the City.\nTo balance these competing interests, Staff has proposed that the City revise VMC 8.22 “Camping” from a system in which camping is criminalized everywhere from 6:30a.m. to 9:30p.m., to one that seeks to address a variety of competing interests by (a) legalizing camping within Supportive Campsites, (b) prohibiting camping 24/7/365 in certain ‘camping impact areas’ to include ecologically sensitive areas, (c) allowing camping at night throughout most of the City, and (d) establishing an exemption for nighttime workers.\nAccompanying this Staff Report are two ordinances for Council’s consideration (“Ordinance Option A” and “Ordinance Option B”). The only distinction between the two versions is the verbiage relating to Camping Impact Areas. Both ordinances indicate that unless occurring within a City-approved Supportive Campsite, camping shall be illegal 24/7/365 within Camping Impact Areas. However the locations of the Camping Impact Areas differ as follows:\nThe term “Camping Impact Areas” means:\nBoth Ordinances:\n1000’ from Supportive Campsites;\nAt a public water station, wastewater or stormwater facility; and\nOrdinance Option A\nOrdinance Option B\nWithin two hundred feet (200’) of the nearest edge of the Columbia River, Vancouver Lake, Burton Channel, Peterson Channel, Fisher’s Creek, or Burnt Bridge Creek.\nUpon land classified as one or more of the following:\na. Habitats of Local Importance as defined by VMC 20.740.100;\nb. Riparian Buffers of Fish and Wildlife Habitat Conservation areas as defined by VMC 20.740.110;\nc. Frequently Flooded Areas as defined by VMC 20.740.120; or\nd. Wetland Buffer area of Wetlands as defined by VMC 20.740.140.\nStaff recommends adoption of Option A for a few reasons. First, Option A is more easily mapped and provides greater clarity to the public and law enforcement regarding areas where camping is prohibited. Additionally, the designations of flood areas, wetlands, and habitat conservation areas under Option B will change over time with environmental changes, so a Critical Areas Protection Map would need to be continuously updated, which may cause more uncertainty regarding the location of Camping Impact Areas. Finally, Option B may be over-inclusive in protecting environmentally sensitive areas. For example, during certain seasons, designated wetlands are dry and isolated camping may not have a significant impact on such land.", "pred_label": "__label__POS", "pred_score_pos": 0.9364076852798462} +{"content": "Decentralized exchanges play a crucial role in the broader cryptocurrency ecosystem. They facilitate the trading of and swapping between assets without constraints. It is a matter of time until the DEXes generate a combined $1 trillion in 12-month volume, and that may even happen this year.\nThe Ongoing Growth Of DEX Trading\nIt is not entirely surprising to see decentralized exchanges gain such a high market share lately. While centralized trading platforms remain ever-popular, many users explore other options. Unlike a centralized platform, a DEX can offer trading pairs and swaps that would otherwise require one or multiple intermediary “hops.” Convenience is crucial in the crypto world, and users will go wherever they can trade freely without restrictions.\nMoreover, it is crucial to note there are more decentralized exchange opportunities than before. On the one hand, there are still new platforms coming to market. A competitive ecosystem is crucial to fuel further innovation and improvements. On the other hand, there are also existing DEXes exploring cross-chain functionality. It broadens the ecosystem, introduces opportunities for other assets, and creates a better overall trading experience.\nToday, the DEXes combine for over $900 billion in 12-month volume. An impressive statistic, considering how the monthly volume was relatively low for most of 2020. Things only started picking up in January 2021 and beyond, with a massive peak in May of this year. Those levels have not been reached again, although the industry is still in a very good place.\nMoreover, it appears that reaching $1 trillion and more in 12-month volume will occur relatively soon. The monthly volume for August, November, and December 2020 was relatively low. These days, DEXes generate over $70 billion in monthly volume. With that average, it should take until late November to reach that $1 trillion mark. An impressive development for an industry few people thought could survive two years ago.\nSustaining Growth is Crucial For DEXes\nAlthough the May 2021 volume peak still baffles many, it is essential to look at the bigger picture. Sustaining over $120 billion in monthly volume is, under the current circumstances, impossible. However, all DEXes combine for a much higher monthly volume compared to 2019 and 2020. That trend is visible all year long and should run until the end of the year with ease.\nThe bigger question is which platform will offer some competition against Uniswap. So far, that has been a tough task for all other DEXes. Sushiswap is the only other decentralized platform surpassing $10 billion in monthly volume. Curve, 0x Native, DODO, Balancer, and Bancor Network will need to step up their game to remain competitive. Unfortunately, it appears those protocols all struggle to captivate users and their liquidity.", "pred_label": "__label__POS", "pred_score_pos": 0.8393446207046509} +{"content": "Separate yourself from other people in your home, in a well-ventilated bedroom. No family member should stay or sleep in the same room as you. Use a separate bathroom. If you have to share a bathroom, clean and sanitize after every use. Avoid sharing items and the same spaces with other people and clean and sanitize frequently touch surfaces often. Wear facemasks to help prevent the spread of the virus to others. Cough or sneeze into the fold of your elbow. Alternatively, cover your mouth and nose with a tissue when you cough or sneeze and dispose of tissue in a dedicated bin. Clean your hands often with soap and water for at least 20 seconds or with alcohol-based hand sanitizer that contains 60-95% alcohol.\n- Advertisement -", "pred_label": "__label__POS", "pred_score_pos": 0.9978458285331726} +{"content": "Wikipedia Linking - Bremelanotide\nGoogle Scholar Search - Bremelanotide\nDrug Information Portal (U.S. National Library of Medicine) - Bremelanotide\nPubChem Compound Summary - Bremelanotide\nDrug Bank - Bremelanotide\nKEGG (Kyoto Encyclopedia of Genes and Genomes) - Bremelanotide\nhttp://www.ebi.ac.uk/\n- Bremelanotide\nhttp://www.ncbi.nlm.nih.gov/ - Bremelanotide\nhttp://toxnet.nlm.nih.gov/\nHazardous Substances Data Bank - Bremelanotide\nhttp://www.ingentaconnect.com/\nIn both normal and ED men, treatment with Bremelanotide causes significant increases in erectile activity, in a dose-dependant manner [10]. Clinically and statistically effective doses of the drug (up to 20mg) are safe and well tolerated by both normal and ED patients [12]. Having completed all Phase II trials in men with promising results, Bremelanotide is set to enter Phase III for men in the first half of this year. In women, positive data from a Phase IIa trial and the recent commencement of a Phase IIb trial suggest that entry to Phase III for women may also be on the horizon. If approved, Bremelanotide would be the first FDA-approved synthetic aphrodisiac. This novel therapy could potentially address the substantial need for an effective female sexual dysfunction treatment as well as offer an alternative to traditional PDE inhibition in ED men.\nhttp://www.researchgate.net/\nBremelanotide: The peptide-melanocyte stimulating hormone (MSH) is a product of the proopiomelanocortin pro-hormone. This peptide has long been known to be involved in regulation of energy homeostasis and has been suggested as a target for number medical indications (Hedlund 2004). In the mid-1980s, a group at the University of Arizona synthesized two highly potent MSH analogues (Hadley et al. 1998). One compound, deemed Melanotan I (MTI) was licensed out and further characterised for utility as a tanning drug, given the known role of MSH in pigmentation. A further analogue, Melanotan II (MTII) was developed which was smaller and the hope was that this would aid in its absorption and tissue distribution. The investigator decided to assess for himself whether this second analogue had the tanning capability seen with MTI and proceeded to dose himself. While it is unclear whether he did achieve a tan, what the investigator reports was an “unrelenting” erection lasting 8 hours. Not long after, this compound was licensed out for further development as a sexual dysfunction treatment candidate. PT-141 is the active metabolite of MTII and ultimately became the drug development lead compound and was renamed bremelanotide. Clincal trials in women have demonstrated that bremelanotide increases sexual desire and arousal in women with arousal disorders (Diamond et al. 2004; Diamond et al. 2006; Safarinejad 2008). In one study, using vaginal plethysmography to assess vasocongestion, even though subjective scores were increased over placebo, there was no change in vasocongestion measures as compared to controls, confirming that vaginal vasocongestion is not a suitable method for assessing efficacy of compounds (Diamond et al. 2006). Prior to the discovery and development of bremelanotide, melanocortin receptors were not considered to be of great interest within the sexual medicine field. Since that time, a surge of interest has appeared, and along with it a boost in scientific research investigating the mechanisms involved.", "pred_label": "__label__POS", "pred_score_pos": 0.5617842078208923} +{"content": "Importance: Safety-net hospitals (SNHs) operate under limited financial resources and have had challenges providing high-quality care. Medicaid expansion under the Affordable Care Act led to improvements in hospital finances, but whether this was associated with better hospital quality, particularly among SNHs given their baseline financial constraints, remains unknown. Objective: To compare changes in quality from 2012 to 2018 between SNHs in states that expanded Medicaid vs those in states that did not. Design, setting, and participants: Using a difference-in-differences analysis in a cohort study, performance on quality measures was compared between SNHs, defined as those in the highest quartile of uncompensated care in the pre-Medicaid expansion period, in expansion vs nonexpansion states, before and after the implementation of Medicaid expansion. A total of 811 SNHs were included in the analysis, with 316 in nonexpansion states and 495 in expansion states. The study was conducted from January to November 2020. Exposures: Time-varying indicators for Medicaid expansion status. Main outcomes and measures: The primary outcome was hospital quality measured by patient-reported experience (Hospital Consumer Assessment of Healthcare Providers and Systems Survey), health care-associated infections (central line-associated bloodstream infections, catheter-associated urinary tract infections, and surgical site infections following colon surgery) and patient outcomes (30-day mortality and readmission rates for acute myocardial infarction, heart failure, and pneumonia). Secondary outcomes included hospital financial measures (uncompensated care and operating margins), adoption of electronic health records, provision of safety-net services (enabling, linguistic/translation, and transportation services), or safety-net service lines (trauma, burn, obstetrics, neonatal intensive, and psychiatric care). Results: In this difference-in-differences analysis of a cohort of 811 SNHs, no differential changes in patient-reported experience, health care-associated infections, readmissions, or mortality were noted, regardless of Medicaid expansion status after the Affordable Care Act. There were modest differential increases between 2012 and 2016 in the adoption of electronic health records (mean [SD]: nonexpansion states, 99.4 [7.4] vs 99.9 [3.8]; expansion states, 94.6 [22.6] vs 100.0 [2.2]; 1.7 percentage points; P = .02) and between 2012 and 2018 in the number of inpatient psychiatric beds (mean [SD]: nonexpansion states, 24.7 [36.0] vs 23.6 [39.0]; expansion states: 29.3 [42.8] vs 31.4 [44.3]; 1.4 beds; P = .02) among SNHs in expansion states, although they were not statistically significant at a threshold adjusted for multiple comparisons. In subgroup analyses comparing SNHs with higher vs lower baseline operating margins, an isolated differential improvement was noted in heart failure readmissions among SNHs with lower baseline operating margins in expansion states (mean [SD], 22.8 [2.1]; -0.53 percentage points; P = .001). Conclusions and relevance: This difference-in-differences cohort study found that despite reductions in uncompensated care and improvements in operating margins, there appears to be little evidence of quality improvement among SNHs in states that expanded Medicaid compared with those in states that did not.", "pred_label": "__label__POS", "pred_score_pos": 0.7088053822517395} +{"content": "In 1996, Bill Gates coined the memorable phrase \"Content is King.\" This credo has stood the test of time, but a succession is underway. The new king is data. Data is the most valuable business asset, and how you leverage it defines business success.\nThis presents a challenge when managing your data assets in a cloud-native environment. The traditional database strategy is unfit for cloud-native architecture. Essentially, no \"one\" database solution addresses how to manage and effectively persist data in the cloud. Instead, you must build a new strategy for how you manage different data types to meet operational SLAs.\nWhat do you need for your \"succession plan?\" We will look at three items to inform your strategy: baseline database requirements, existing database technology, and database management options available for a cloud-native environment.\nA crown to fit the king – What are the requirements?\nWhen you scan today's data management market, you realize you have to reset your thinking. Instead of looking for \"one\" database to address your requirements, focus on how you manage your data in a cloud-native architecture. Anchor your initial workflow to map and address persisting a myriad of data types on the cloud that align with your specific business requirements.\nWhat is required for a good fit? The following are fundamentals for fully leveraging a cloud-native mode:\n✔ Portability - Ability to deploy in your chosen infrastructure (private, public, hybrid) with flexibility to migrate with minimal business impact.\n✔ Cloud-native fundamentals of ephemerality - Architecting around ephemerality to achieve significant gains for what matters most - serviceability.\n✔ Scalability and high performance - 5G demands ultra-low latency. You must comply with telco-grade SLA requirements for applications and databases.\n✔ TCO - Optimize required data management and associated TCO with new use cases and growing traffic.\n\"The One\" - What does the database market offer?\nLet's examine database technology in today's market. Typically, databases are optimized to handle specific classes of data and related management scenarios. For the capability to manage all BSS domain database performance scenarios, however, no traditional database fully meets cloud-native business requirements. For example:\nWhile there are many database options, the cautionary tale is that no \"one\" is a true fit for data management needs in a cloud-native architecture. Thus, the king needs access to many crowns for different occasions.\nNew approach required: King of many crowns\nImplementation of core products requires you re-architect BSS solutions and adopt a cloud-native data persistence (CDP) approach. This approach analyzes data technologies and performance requirements against cloud-native databases and managed products serving cloud infrastructures. The CDP approach assesses performance metrics, use cases, data types, and operational scenarios (e.g., charging, billing, analytics, customer management, self-management), providing an optimal baseline. It focuses on achieving cloud-native data management success versus the underlying technology. Four performance principles anchor this approach.\n#1: Portability and high performance\nSupport various deployment options with same software version- \"Implement once, deploy often.\" Data technologies need flexibility to use multiple infrastructures from private or public cloud, hosted or managed infrastructure, and the ability to react on local conditions for datacenter setups, intersite latency, regional distribution, etc., especially when architecting an active/action solution. Autotuning- Technologies, different infrastructures, and new hardware provide tuning options. Have the data layer localized and autotune to key variables, including deployment resources, resiliency settings, and application profile, enabling you to maintain a \"zero-touch\" principle. #2: Cloud resource availability and reliability\nUnexpected resource removal- Database technology must operate in a container orchestration environment and acknowledge a resource will unexpectedly disappear, meaning designs implicitly contain resiliency from resource level up. Verify algorithm on non-functional behaviors- The algorithm on resiliency from node recovery, scaling in/out, and upgrade process are often the same. Ensure zero business impact on maintenance activity or failover scenario. A true cloud database will continue with no serviceability interruptions. #3: Elasticity and latency SLA Distributed setup elasticity - High-availability systems need clear architecture for scalability, resilience, and data durability. To ensure you meet SLA:\n-Choose your \"sync\" model carefully to achieve performance and resiliency.\n-Change the database access pattern to tune queries to achieve low latency.\n-Remove data unneeded for your core, decompose and orchestrate it via a message bus, and move to near-real-time, cloud-native app processes.\n-Ensure resiliency design, so probability of failure matches utilization of database resources.\nLatency when scaling - Distributed data layers have partitioning mechanisms that do the corresponding split to resources with different available algorithms. Verify which fits you best and how to tune scaling to avoid latency impact. #4: Balance cost for best TCO\nDecide impact of lost resources- Distribute resources to ensure best resiliency. Define maximum impact (e.g., 30% resource loss, continue handling 100% traffic, zone failure). Define the RTO/RPO corresponding to resource restoration and align to capabilities the infrastructure provides. Managed resources- You may need more resources to achieve your SLA, such as storage. Because IOPS is the limiting factor, scaling is only possible with dedicated utilization, etc. Data is king\nTim O’Reilly, founder of O'Reilly Media, sums up the new world well — \"Who has the data has the power.\" With data your most valuable asset, proper management is vital to accelerate your business velocity. The foremost stage of your journey must include architecting your data management based on principles that underpin a cloud-native solution.\nToday, no single database provides a robust enough solution for the full range of cloud-native data management scenarios. Thus, a CDP approach provides a strategy for managing telecom's varying data types across operational scenarios, ensuring your most valued asset is leveraged for your business success.\n— John Giere, President and CEO of Optiva, Inc. ([email protected])", "pred_label": "__label__POS", "pred_score_pos": 0.6761409044265747} +{"content": "These effects remain poorly understood, however. One of the most plausible links between cross-border refugee flows and the spread of conflict has to do with the impact of migration flows on the ethnic balance of host countries. Cultural similarity may facilitate refugee integration, but refugee flows can also foster tensions among ethnic groups. However, there is a lack of systematic data on the ethnic composition of refugee flows, making it difficult to test these claims. Existing datasets, available from the United Nations High Commissioner for Refugees, list refugee host and asylum countries, along with aggregate refugee counts. However, information on refugee ethnicity, religion, language use, etc, is not currently available.\nWe propose the creation of two datasets, which will help improve research on the migration-conflict connection. The first is a global dataset which contains information on the primary ethnic group(s) of refugee flows between states, at the aggregate country-dyad level. The second dataset will offer a geographically disaggregated view of these flows, listing refugee point of origin in the sending country and point of settlement in the receiving country. These projects will require extensive data collection efforts in conjunction with the United Nations High Commissioner for Refugees, which collects census data on refugee camps.\nThese projects will be based in Zürich and Geneva, with input from international collaborators. The Zürich team will collect the global refugee data using secondary materials, NGO documents, and news reports. The Geneva team will work closely with relevant UNHCR offices to collect the geographically disaggregated data. The project will result in at least two research papers, dissertation projects, and publically-available data for the academic and policy communities.\nproposal", "pred_label": "__label__POS", "pred_score_pos": 0.533591628074646} +{"content": "Objective: To determine the prevalence of multiresistant organism (MRO) colonisation of reusable venesection tourniquets. Design and setting: A prospective study in a tertiary hospital to collect and analyse reusable venesection tourniquets for the presence of MROs - methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and extended-spectrum β-lactamase and metallo-β-lactamase-producing Enterobacteriaceae - using a sensitive enrichment method. Tourniquets were collected and tested during a 10-week period between September and November 2010. Main outcome measure: Prevalence of MRO colonisation of tourniquets. Results: The overall colonisation rate of 100 tourniquets randomly collected from general wards, ambulatory care areas and critical care areas was 78%. MROs were isolated from 25 tourniquets collected from a variety of hospital locations, including general wards, the intensive care unit, burns unit and anaesthetic bay. MRSA was isolated from 14 tourniquets and VRE from 19; both MRSA and VRE were isolated from nine tourniquets. There were no microorganisms isolated from 22 tourniquets. Conclusion: Reusable tourniquets can be colonised with MROs and may be a potential source of transmission of MROs to hospitalised patients.", "pred_label": "__label__POS", "pred_score_pos": 0.7800124883651733} +{"content": "dc.contributor.author Pullagura, Gokul Raj dc.contributor.author Waite, Nancy M dc.contributor.author Houle, Sherilyn KD dc.contributor.author Violette, Richard dc.contributor.author Wong, William WL dc.date.accessioned 2020-06-19T01:26:48Z dc.date.available 2020-06-19T01:26:48Z dc.date.issued 2019 dc.identifier.issn 1544-3191 dc.identifier.doi 10.1016/j.japh.2019.02.011 dc.identifier.uri http://hdl.handle.net/10072/394737 dc.description.abstract Background:Despite the availability of free and accessible influenza vaccine to all Ontarians, uptake has remained suboptimal. Although reasons to not receive the vaccine vary widely, health care provider recommendations remain the most effective strategy to positively influence vaccination decisions.Objectives:This study aimed to predict the relative quality of life, costs, and cost-effectiveness of introducing a remunerated community pharmacist consultation service on influenza vaccination for Ontarians aged ≥ 65 years.Methods:A cost-utility analysis was performed from a third-party public payer perspective over 1 year. The delivery of consultation services by community pharmacists on influenza vaccination, billable at CAD $15 was compared with current standard practices (absence of remunerated consultations). Model inputs were derived primarily from existing literature. The impact of parameter uncertainties was assessed through deterministic and probabilistic sensitivity analyses.Results:The provision of influenza vaccine consultation services was predicted to prevent 2407 cases of mild influenza and 3 influenza-related deaths at an additional cost of CAD $2.03 per person over current practices. The incremental costs per quality-adjusted life-year (QALY) gained for the enhanced care strategy compared with standard care was CAD $2087. The interpretation of the base-case result was found to be robust across all sensitivity analyses. The projected additional costs of implementing pharmacist consultations in Ontario was estimated at CAD $1.15 million per year, and the anticipated benefits included a gain of 507 QALY per year.Conclusion:Pharmacist-delivered consultation services on influenza vaccination are cost-effective and lead to improved clinical outcomes for Ontario seniors. Introduction of such services offers a promising strategy to address challenges related to poor vaccine uptake in this group. dc.description.peerreviewed Yes dc.language English dc.language.iso eng dc.publisher Elsevier dc.relation.ispartofpagefrom 489 dc.relation.ispartofpageto 497.e1 dc.relation.ispartofissue 4 dc.relation.ispartofjournal Journal of the American Pharmacists Association dc.relation.ispartofvolume 59 dc.subject.fieldofresearch Pharmacology and Pharmaceutical Sciences dc.subject.fieldofresearch Public Health and Health Services dc.subject.fieldofresearchcode 1115 dc.subject.fieldofresearchcode 1117 dc.title Cost-utility analysis of offering a novel remunerated community pharmacist consultation service on influenza vaccination for seniors in Ontario, Canada dc.type Journal article dc.type.description C1 - Articles dcterms.bibliographicCitation Pullagura, GR; Waite, NM; Houle, SKD; Violette, R; Wong, WWL, Cost-utility analysis of offering a novel remunerated community pharmacist consultation service on influenza vaccination for seniors in Ontario, Canada, Journal of the American Pharmacists Association, 2019, 59 (4), pp. 489-497.e1 dc.date.updated 2020-06-17T19:56:48Z gro.hasfulltext No Full Text gro.griffith.author Violette, Richard", "pred_label": "__label__POS", "pred_score_pos": 0.8280453681945801} +{"content": "Monolayer graphene finds practical applications in many fields, thanks to its desirable intrinsic properties. However, these properties can also limit its potentials. The addition of foreign atoms can help, but requires precise control. Now, researchers from South Korea invented a simple methodology to achieve fine control over the integration of foreign atoms with graphene, developing composite graphene-based heterostructures that can be used to store energy at low cost and fabricate ultrathin, wearable electronics.\nFew materials have stolen the limelight like graphene. Since its discovery, graphene has become the go-to for nearly any technology out there, thanks to its exceptional properties such as high surface area, chemical stability, and high mechanical strength and elasticity. However, despite its seemingly limitless applications, graphene's potential remains underutilized due to several factors, most notably its single-atom thickness, chemical inertness, and the lack of an energy gap.\nOne way to overcome these limitations is by integrating graphene with other materials, such as metals, insulators, and semiconductors, to form composite structures with desirable properties. For instance, researchers are adding metal oxides to graphene to create graphene monolayer/metal-oxide nanostructures (GML/MONSs) that have improved physical and chemical properties. However, depositing uniform layers of metal oxides over graphene without disturbing the characteristics of the graphene layer is extremely challenging.\nIn a new study published in\nNano Energy, a team of materials scientists from South Korea has now developed GML/MONSs by using a low-temperature technique known as electrochemical deposition, in which they grew metal-oxide nanostructures exclusively on the native defect sites of graphene. They achieved this by immersing a single-atom-thick graphene layer in a metal-oxide precursor solution. By adjusting the deposition time, the scientists were able to precisely deposit the metal oxide onto the graphene monolayer, creating composite structures with unique properties in the process. \"Metal-oxide integrated graphene monolayers with lower densities (≤30 μg/cm 2) possess fewer defects, whereas those with higher densities have synergistic characteristics,\" explains Professor Sungwon Lee from Daegu Gyeongbuk Institute of Science & Technology (DGIST), South Korea, who was a part of the research team.\nTo read more,\nclick here.", "pred_label": "__label__POS", "pred_score_pos": 0.8429946899414062} +{"content": "Cacao powder is a superfood packed with flavanoids and antioxidants.\nAlthough cacao and cocoa are derived from the same tree, but cacao is more nutritious overall.\nVegan dessert recipes call for cacao powder because of its minimal processing and nutrition density.\nThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. This product is a natural dietary supplement intended for nutritional support. Please consult your physician for personalized medical advice.\nStore tightly closed in a dry place at room temperature of 59-86 F (15-30C).", "pred_label": "__label__POS", "pred_score_pos": 0.7640223503112793} +{"content": "CONCEPTUAL ANALYSIS article Extended Theoretical Framework of Parental Internet Mediation: Use of Multiple Theoretical Stances for Understanding Socio-Ecological Predictors 1Institute of Social and Cultural Studies, University of the Punjab, Lahore, Pakistan 2Department of Public Health, Institute of Social and Cultural Studies, University of the Punjab, Lahore, Pakistan 3Institute of Public Health, Charité – Universitätsmedizin Berlin, Berlin, Germany 4Institute of Gerontological Health Services and Nursing Research, Ravensburg-Weingarten University of Applied Sciences, Weingarten, Germany\nDigital media is a common phenomenon in contemporary societies. Recognizing the popularity of digital and online devices among the younger generation, the subject of parental internet mediation is of utmost significance for avoiding the adverse effects of digital media on the physical, cognitive, and social wellbeing of youngsters. Taking insights from an informed review of multi-grounded theories, we propose an extended framework of socio-ecological predictors concerning parental internet mediation. This contribution offers an innovative methodological and analytical perspective to consider both psychological and behavioral predictors for promoting resilience. This review acknowledged resilience as a strength-based measure to ensure online safety among young individuals. This review suggests that an integrated socio-ecological approach is critical to formulating the basis for a theoretical framework to fully comprehend the socio-ecological predictors of parental internet mediation.\nIntroduction\nParental mediation in internet use of young children, teenagers, and adolescents is widespread in both developed and developing countries. It is one of the critical agendas of contemporary societies because almost all young individuals, growing up in the age of digitalization, use media and the internet in their daily routine (Hassan et al., 2020). The relationship of youngsters with digital media is diverse, highlighting multiple challenges in a varied sociocultural context (Green et al., 2020). The harmful effects of digital media have been discussed in recent years, particularly focusing on the physical and psychological health of the younger generation, including children and teenagers (Ferrara et al., 2017; Bruggeman et al., 2019; Biernesser et al., 2020; Hassan et al., 2020; Twenge and Martin, 2020). Large evidence pointing to issues such as internet addiction (Kawabe et al., 2016), cyberbullying and cybervictimization (John et al., 2018; Lin et al., 2020), and adverse health effects of online gaming (Paulus et al., 2018; Stenseng et al., 2020) is available. Predominantly, the outcomes are related not only to cognitive and mental health and sociability indicators (Bilgrami et al., 2017; Green et al., 2020) but also to self-inflicted violence (Deslandes and Coutinho, 2020), sleep habits, and quality of life (Kawabe et al., 2019).\nTo reduce the adverse effects of digital media on the physical, cognitive, and social wellbeing of children and teenagers, parental mediation is expected to be a successful approach. Parental mediation is a multi-pronged concept and facilitates in building and enhancing essential digital skills (Livingstone, 2008; Lin et al., 2019; Green et al., 2020). The concept of parental mediation is mainly situated within the media effects paradigm, which is primarily rooted in communication and deals with social, psychological, and developmental perspectives (Mendoza, 2009; Clark, 2011; Livingstone et al., 2015a). Reciprocal relationship between parents and the younger generation, their social environment, and psychological needs is of utmost importance in this regard (Clark, 2011; Green et al., 2020). The discourse of parental mediation explores how parents interact, regulate, or manage the use of media or the internet, particularly in mitigating negative effects on the physical, psychological, and emotional health and sociability of children/teenagers (Mendoza, 2009; Green et al., 2020).\nParents are the main socializing agents and gatekeepers for the younger generation to access media and digital devices. They ensure the adequate use of media regarding content and time by their children. In this study, the younger generation is referred to as children, teenagers, and adolescents. Research on parental mediation encompasses all of these age groups. This is due to the fact that childhood, teenage, and adolescence all are transitional phases of human life, where young individuals experience new things, reject normative ideas, and prefer to adopt unique lifestyles (Flanagan et al., 2015). Though, there is a difference among the nomenclature and age groups due to the transition from childhood to adolescence, where children include both preschool and school-age children, teenagers (13–19 years), and adolescents [10–19 years; Flanagan et al., 2015; Aierbe et al., 2019; WHO (World Health Organization), n.d.]. Nonetheless, Havighurst (1972) labeled children, teenagers, and adolescents as a unitary group in view of their developmental tasks. Further, these are the most common age groups used in the literature concerning parental mediation because parental control plays a decisive role in the regulation of their behavior. Furthermore, these groups are most vulnerable to the risks associated with both media and internet due to the lack of e-maturity, more close contact with peers, inadequate capacity for self-regulation, and self-efficacy to cope with risks (O’Keeffe and Clarke-Pearson, 2011; Aierbe et al., 2019). For that reason, they require parental attention and mediation.\nBased on the abovementioned context, this review acknowledges the need for an overarching framework of parental internet mediation in the context of a digital media-rich environment. Therefore, it aims to seek guidance from the review of multi-grounded theories to enrich the sociological inquiry and design an extended framework for the socio-ecological predictors of parental internet mediation. This review is structured into four main sections. Section 1 describes the introduction and context of the study, followed by the objective and structure of the study. Section 2 highlights the contribution of the existing literature to parental internet mediation and explains the particular theoretical assumptions of multi-grounded theories. This section critically debates and identifies key predictors of parental internet mediation, which impact at various levels (the level of children/teenagers, parental level, and contextual level). Section 3 synthesizes, summarizes, and proposes an extended theoretical framework for the socio-ecological predictors and motivating factors of parental internet mediation, followed by the conclusion in Section 4.\nPredictors of Parental Internet Mediation\nDigital media and technology lead to both advantages and challenges in contemporary societies. This contribution focuses on parental internet mediation, recognizing the popularity of digital and online devices among the younger generation. This article discourses on various predictors of parental internet mediation, using relevant theoretical stances to comprehensively extend the existing framework with a socio-ecological approach. Although excessive use of the internet is one of the significant predictors of parental internet mediation, nonetheless, there are other multiple contributing and contextual factors, which are essential to be considered, enhancing digital literacy and empowering the younger generation to manage risks (Lin et al., 2019).\nVarious strands correspond to comprehend the framework and ideologies of parental internet mediation and their related factors. At the very onset, the academic discourse of parental mediation emerged from communication and media studies due to the advent of TV and video games. At that time, communication and media experts were concerned to understand the effects of TV and video games on the behaviors of children (Rothfuss-Buerkel and Buerkel, 2001; Livingstone et al., 2015a; Aierbe et al., 2019). However, soon it evolved as an important subject in the field of social psychology to comprehend the motives of parental mediation, in view of an array of digital devices and media-rich environment (Clark, 2011; Iqbal, 2019; Lin et al., 2019; Iqbal et al., 2021). In this context, the parental mediation theory emerged and underwent a critical review over a period of time (Clark, 2011; Iqbal, 2019).\nResearchers coined various typologies on parental mediation to address the changing context of media and digital devices. They attempted to understand parental mediation and its related factors to apply various methodological and philosophical assumptions and to share some common questions, nonetheless with different theoretical perspectives (Clark, 2012). The variation in opinions of researchers highlights their own conception of theory and its application according to their own context and interests (Clark, 2012). This argument is well-established by the fact that the word “theory” is a broader and an applied term, which has diverse meanings in various disciplines such as sociology and communication.\nIn the field of communication, Craig (1999) observed that theory is a radically different conception and discussion of communication problems and practices. Similarly, theory or semantic predicament is an important expression in the lexicon of contemporary sociology, having multiple definitions and concepts (Abend, 2008). Abend (2008) categorized numerous definitions, describing that theory is a “logically connected system of general propositions,” an “explanation of a particular social empirical phenomenon,” an “overall perspective to see and interpret the social world,” an “account of a fundamental normative component,” and the “discussions about the ways by which reality is socially constructed.” Broadly, theory may be comprehended as the explanation and interpretation of a social phenomenon within a social context.\nTaking insights from various theories, this contribution is intended to provide some critical aspects for extending the framework of socio-ecological predictors of parental internet mediation. Largely, a theoretical framework is viewed as an organizing structure, which conveys meanings to any situation and creates linkages between predictors (Baldwin et al., 2003). It is observed that social, psychological, and communication researchers used several methodological approaches for understanding the social context and related factors which influence behavior (Clark, 2012). Based on the analysis of the parental internet mediation literature, this study argues to adopt a multi-grounded theoretical framework, accounting for both parental and children level factors. This contribution, an interplay of various theories, is found to be interesting and relevant for researches to explore various predictors of parental internet mediation, applying both quantitative and qualitative research methods to explain social reality (Iqbal, 2019). In the following sections, we present an overview of multiple theoretical perspectives, followed by a debate along with a comprehensive, proposed, and extended socio-ecological theoretical framework. Keeping in view the objective of this study, four theories have been selected for the academic discourse: the parental mediation theory, the ecological theory of development, the protection motivation theory, and the theory of resilience. These are explained in the following subsections. The parental mediation theory was prioritized, as it is the focus of this study, while the ecological theory of development (Bronfenbrenner, 1979) was chosen by considering the developmental stages of children/teenagers. Furthermore, the protection motivation theory (Norman et al., 2005; Plotnikoff and Trinh, 2010) was used to understand the preference of parents for mediation in view of vulnerability of youngsters to online risks and efficacy of coping with the risks. Finally, the social and ecological theory of resilience (Ungar, 2011) was incorporated to extend the theoretical assumptions of parental internet mediation. In this contribution, resilience is acknowledged as a strength-based measure and positive adjustment against challenges or risks to ensure online safety.\nParental Mediation Theory\nThe parental mediation theory was originated to examine the effects of TV on children and teenagers in media and communication. Initially, researchers coined three dimensions of parental mediation, i.e., active, restrictive, and co-view mediation (Nathanson, 1999, 2002; Martins et al., 2015), which were, later on, applied to video games, the internet, and smartphones. St. Peters et al. (1991) expanded the parental mediation theory in four dimensions, which are distinguished according to the type (active vs. regulated) and level (high vs. low) of mediation. High levels of active and regulative mediation are referred to as selective mediation, whereas low levels of both are called as Laisses Faire (or unmediated). Highly active and low regulated mediation is promotive and highly regulated but low active is labeled as restrictive mediation (Wright et al., 1990; St. Peters et al., 1991; Truglio et al., 1996; Livingstone and Helsper, 2008).\nIn addition, Clark (2011) adopted a critical stance for the parental mediation theory and employed participatory learning as a further dimension of parental mediation, highlighting the role of communication between the parents and their children for being active participants. However, Clark (2011) identified gaps in the existing parental mediation theory in relation to digital and mobile media. Nikken and Jansz (2014) addressed this gap and introduced five dimensions of parental mediation to regulate online behavior in view of digital media: active, restrictive, co-use mediation on access, content, and supervision. Livingstone et al. (2015b) adopted a holistic approach and acknowledged the complexity of online digital and portable devices, specifically for parents to manage. Livingstone et al. (2015b) also categorized five dimensions of parental internet mediation, which are more comprehensive and widely adopted: active co-use or instructive, restrictive, monitoring, technical, and active internet safety mediation. Later, Livingstone et al. (2017) defined two broader dimensions of parental internet mediation, i.e., enabling and restrictive mediation, which provides a reorganization of the dimensions and underlines the interactive nature of mediation. Enabling mediation encompasses active mediation in coupling with safety and technical mediation and monitoring. Although the abovementioned five dimensions are very pertinent in the present digital media-rich environment; however, we believe that Laissez Faire or unmediated dimension is also essential and must be included as the sixth dimension of parental internet mediation, as few parents either mediate less or remain unmediated according to their cultural practices (Iqbal, 2019; Iqbal et al., 2021), which may affect the positive outcomes of children/teenagers.\nTo sum up, the parental mediation theory has evolved over time with the growth of media and digital technology and classified six key dimensions, which are essential to be considered: active co-use or instructive, restrictive, monitoring, technical and active internet safety mediation, Laissez Faire, or unmediated. Along with the dimensions of parental mediation, several researchers also identified some predictors of parental internet mediation (Clark, 2011; Symons et al., 2017; Clay, 2019; Lin et al., 2019). However, to establish a more thorough understanding and explanation of the socio-ecological predictors of parental internet mediation, the consultation of further theories is required as explained in the following sections.\nEcological Theory of Development\nClark (2011) found few limitations in the parental mediation theory in terms of its prime focus on negative effects of media on the cognitive development of children, while overlooked processes shaping parental mediation, especially the parent–child relationship. Therefore, Clark (2011) recommended that attention should be paid to the sociology of childhood to delimit the parental mediation research. In this context, the ecological theory of development has been selected for an extended framework. The ecological theory of development by Bronfenbrenner (1979) provides a basis for understanding the environment of children and teenagers in the context of development classifying into the following five integrated systems:\na. Microsystem: the relationship between children/teenagers and an immediate environment, such as family and friends.\nb. Mesosystem: the relationship between two or more microsystems where children/teenagers actively participate, such as at home and school.\nc. Exosystem: an indirect environment, which has a bearing on children/teenagers, such as the working place of parents.\nd. Macrosystem: the prevailing sociocultural and economic conditions of society.\ne. Chronosystem: the system of nested relationships, capturing the lower subsystems over time.\nThe ecological theory highlights certain critical factors of development, shaping the environment of children and teenagers. Specifically, this theory enables in comprehending the current scenario of media and digital landscape around every child/teenager at the level of the home, school/college, and community. Though this theory was developed prior to the revolution of the internet and digital media as well as their developmental impact on children/teenagers, yet, it is considered as the most comprehensive one, focusing on their immediate, direct, and indirect environments.\nAtkin (2001) and Jordan (2004) added that an ecological and overarching perspective, centered on home, is most significant to understand the environment of children/teenagers as digital natives, and their relationships within micro-, meso-, and exo-system. Further, Johnson and Puplampu (2008) acknowledged the role of technology and embedded the concept of ecological techno-subsystem through introducing a new dimension in an immediate environment (microsystem), concerning the interactions of children/teenagers with both living (e.g., peers) and non-living elements of technology (e.g., hardware and digital devices).\nLivingstone et al. (2012) also adopted an ecological approach for investigating online-based activities of children/teenagers and parental mediation within the context of social structures of family, community, and culture. They added three categories while investigating parental internet mediation, i.e., individual-level or microsystem (e.g., home), social mediation (e.g., school/college and peers), and national-level or macrosystem (e.g., cultural values, socio-economic conditions, and regulations). In addition, Livingstone et al. (2015b) also refined an ecological and analytical model and identified various factors at the individual, society, and national level, encompassing demographics, online access, activities, and risks of children/teenagers. Thus, previous researchers applied the ecological theory within media and internet-related studies to comprehend the interplay of various factors (Livingstone et al., 2012, 2015b).\nGiven this context, we included an ecological theoretical perspective to highlight the predictors within the five integrated systems. Since the use of the internet is more personalized and individualized, it is essential to understand the factors concerning the access of children/teenagers. Primarily, the role of the digital environment at home and school/college is most essential to be considered, where children and teenagers have instant access to the internet and internet-connected devices.\nIn view of a digital media-rich environment, we recommend the following predictors using an ecological approach for an extended parental internet mediation theoretical framework (Figure 1), positioning children/teenagers within their environment and nested within the five key integrated systems. These predictors are proposed at the level of children/teenagers, parents, and contexts.\na. The microsystem includes (i) the characteristics of children/teenagers, e.g., age, sex, the level of education, digital skills, types of online activities, and time spent online and (ii) the characteristics concerning their parents, e.g., parental attitude toward the use of internet; level of communication between parent–child/teenager; and the role of peers/friends in the use of internet.\nb. The mesosystem comprises (i) the characteristics of the digital environment of children/teenagers at home and schools/colleges such as availability of internet (WIFI and mobile data package dongles) and internet-connected devices (computer, laptop, tablets, smartphones, smart TV, audio devices, and video game devices); (ii) parental digital skills; and (iii) the role of teachers and peers/friends.\nc. The exosystem includes (i) the characteristics concerning their parents, e.g., parental job nature and workplace and (ii) contextual factors, e.g., the role of mass media and community support.\nd. The macrosystem consists of adherence to prevailing cultural values, beliefs, and customs as well as socio-economic conditions, as contextual factors.\ne. The chronosystem highlights the transition over time.\nIt is envisaged that these predictors altogether at various levels influence the engagement of children/teenagers with digital devices as well as parental preferences for various dimensions of internet mediation in interactive and multilateral ways.\nProtection Motivation Theory\nTaking the frame of reference of parents, the protection motivation theory provides another perspective to explore the factors of parental internet mediation. This theory postulates that intention of an individual to engage in protection behaviors is based on his/her understanding of the adversity, i.e., fear or any other emotion related to the situation, its persuasion, and the coping process. This theory directly indicates the motives of parents of applying mediations based on their perception about the threat (severity and susceptibility) and coping appraisal (response-efficacy and self-efficacy; Rogers, 1983; Norman et al., 2005; Plotnikoff and Trinh, 2010).\nThis theory facilitates to comprehend the preference of parents for applying various dimensions of parental internet mediation (active co-use or instructive, restrictive, monitoring, technical and active internet safety mediation, Laissez Faire, or unmediated), subject to their understanding about online risks and efficacy of children/teenagers in coping up with risks. Broadly, this theory predicts that those parents who perceive online risks as more severe and susceptible to their children or teenagers apply more and diverse mediation. Nevertheless, the parents who perceive their children/teenager as more capable of having sufficient response-efficacy and self-efficacy to prevent risks and perform optimal behavior online apply less mediation or remain unmediated. For that reason, we recommend that parental internet mediation could be predicted as a protective behavior in the face of online risks. Considering the risk perception and protective actions, the protection motivation theory drives in understanding the online safety behavior, keeping in view the cultural variation (Menard et al., 2018). This theory facilitates understanding whether individual sociocultural values motivate to perform a protective behavior and adopt various dimensions of parental mediation.\nDerived from the protection motivation theory, Figure 2 elaborates the potential predictors or motivating factors of parental internet mediation, giving importance to both threat and coping appraisal at parental level, where threat appraisal indicates severity and susceptibility of online risks while coping appraisal signifies response and self-efficacy to prevent online risks.\nTheory of Resilience\nFinally, this study introduces the concept of resilience for theoretical integration, which has various interpretations. Resilience is a dynamic concept and concerned with how individuals respond to risks, stress, or challenges (Rutter, 1987). Several researchers defined resilience in diverse ways, highlighting its compensatory, challenging, or protective factors, where resilience neutralizes exposure to risks, enhances the adaptation of person, or opted as an active problem-solving approach, fostering positive personality characteristics and wellbeing (Ledesma, 2014).\nWe argue that resilience is an effective measure to ensure the online safety of children/teens and to enhance online opportunities. Therefore, we adopted a socio-ecological approach to comprehend the key factors and process of resilience as potential predictors of parental internet mediation. Ungar (2011) theorized the social ecology of resilience as capacity of an individual, in the face of any challenge or adversity, to navigate and negotiate for resources in a culturally meaningful way to sustain wellbeing. In general, the theory of Ungar (2011) explained some basic principles of socio-ecology and emphasized the significance of resources and capacities to adopt resilient pathways. For instance, resilience is linked with own positive adjustments of children/teenagers against challenges or risks (herein referred to as online risks within the context of the internet), demonstrating their capacities to reciprocate and navigate for resources. Ungar (2011) has drawn attention to the role of family and friends as a valuable resource, providing necessary support to the children and teenagers in the face of any risk or challenge.\nRealizing the connotation of resources in nurturing resilience among children and teenagers, it is meaningful to include these aspects in exploring the key factors of parental internet mediation, which vary according to diverse contexts and cultures. The literature revealed both internal and external level factors, which contribute to the ability of an individual to thrive (Carver, 1998; Ledesma, 2014). Internal factors are related to self and personality of an individual, having a significant impact on interpretation of an individual and dealing with adversity, such as positive attitude toward self, cognitive skills, constructive emotions and energy, self-regulation, self-efficacy, core personal values, and motivation to be effective in the environment (Luthar et al., 2000; Wyman et al., 2000; Bonanno, 2004; Patterson and Kelleher, 2005). Predominantly, it is argued that individuals with higher levels of positive personality traits and lower levels of disruptive behaviors are more likely to cope better with risks and build resilience (Affleck and Tennen, 1996; Park et al., 1996; Tedeschi and Calhoun, 1996). On the other hand, external factors influence the ability of an individual to remain resilient while facing adversity. For example, a strong support system and close relationships with family, friends, and community, as the most critical social resource, encourages and reinforces coping skills among individuals to adopt resilient pathways (Rutter, 1987; O’Leary, 1998; Masten, 2001). In this study, the internal and external factors highlight that resilience is indicative of both psychological and behavioral characteristics of children and teenagers.\nGiven the context of online digital environment of children/teenagers and the role of parental internet mediation, it may be stated that children and teenagers are at the exposure to unforeseen online risks. Therefore, parents applied multiple dimensions of parental mediation to build critical thinking, leading to the journey of resilience to reduce any potential harm. Theoretical analysis suggests that the possible predictors for nurturing resilience among children and teenagers could be personal skills, psychological and behavioral characteristics (higher levels of positive personality traits and lower levels of disruptive behaviors), and the support of parents, friends, and teachers to achieve resilient pathways. This study argues that resilience is a strength-based outcome and positive adjustment among children and teenagers against challenges or risks in the context of digital media. Resilience is not a linear process, rather it is iterative, related to the learning of children/teens on how to recognize and manage risks, learn from difficult experiences, and seek appropriate support to recover.\nFigure 3 depicts an illustrative explanation of nurturing resilience among children and teenagers, recognizing both psychological (e.g., personality traits) and behavioral predictors (e.g., disruptive behaviors) for an extended socio-ecological framework of parental internet mediation.\nExtended Theoretical Framework For Predictors of Parental Internet Mediation\nIn the light of the theories described above, we conclude that an integrated approach is critical to formulate the basis for a socio-ecological theoretical framework to fully comprehend the predictors and motivating factors of parental internet mediation. Broadly, this extended framework adopts the socio-ecological resilience model (Ungar, 2011), where children and teenagers are positioned within their environment along with their related characteristics, recognizing the interaction of predictors of multiple levels, particularly at parental and contextual levels. Taking inspiration from all the above given theories, this study also represents resilience as a strength-based discourse to promote positive outcomes among children and teenagers to manage online difficulties. This study acknowledges resilience as both a process and positive outcome against online risks and challenges, resulting from parental internet mediation. Resilience is an iterative process, related to the learning of children/teens, enabling them to recognize and manage online risks, learn from difficult experiences, and seek appropriate support to recover. It argues that resilience is an effective measure to ensure the online safety of children/teens and to enhance online opportunities.\nSeeking guidance from the above theories, this study applies a socio-ecological and multi-methodological approach, unveiling a set of essential predictors to be considered at the level of parents, children/teenagers, and contexts. First, in the level of children/teenagers, the individual characteristics are the most significant, such as age, gender/sex, level of education, digital environment for internet access (means, devices, and place of use), types of online activities, digital skills, time spent online, positive personality traits, less disruptive behaviors, and access to social resources, in the form of support from parents, friends/peers, and teachers for building resilience. Second, in the level of parents, their particular characteristics and beliefs are essential for empirical investigation, e.g., the level of education of parents, employment status, nature of job and workplace, income, own use of the internet, digital skills, the level of communication with children/teenagers, threat appraisal about online risks (severity and susceptibility), and coping appraisal to perform optimal protection behaviors (response-efficacy and self-efficacy). Third, contextual level factors are imperative to be investigated, such as place of residence, socio-economic conditions of families, and cultural values, beliefs, and customs. Figure 4 illustrates the proposed socio-ecological extended framework through connecting the dots and creating linkages among multiple factors of parental internet mediation.\nBased on the above synthesis and prepositions, the proposed extended socio-ecological model combines multiple individuals, contextual, behavioral, and analytical predictors, altogether from both the levels of children/teenagers and parents. We argue that it is necessary to apply a socio-ecological approach to investigate the potential predictors for parental internet mediation, particularly nurturing resilience among children/teenagers to manage online risks in the digital context of contemporary societies.\nThis extended framework model has also been empirically tested in primary research using both quantitative and qualitative designs (Iqbal, 2019; Iqbal et al., 2021). Previous evidence suggests that the above-given set of socio-ecological predictors for the extended theoretical framework of parental internet mediation is quite comprehensive. Nonetheless, there is a requirement of unfolding certain factors to ensure its effective application, such as personality traits and disruptive behaviors, being psychological and behavioral predictors. The most common personality traits are studied in terms of the five big models (Goldberg, 1993), including extrovert vs. introvert, emotionally stable vs. neurotic, agreeable vs. disagreeable, conscientiousness vs. lack of direction, and openness vs. closeness to experiences. Among these, only the positive attributes of personality will help to build resilience. Conversely, the disruptive behavior, the negative emotions or reactions against a particular situation, could be internalized or externalized, focusing inward or outward (Achenbach et al., 1991). Regarding the internet, internalized disruptive behaviors may include high depression and anxiety or low self-esteem while externalized disruptive behaviors include high aggression, delinquency, or the use of drugs or smoking may also be considered. The operationalization of most of the predictors is available and is used in several studies (Achenbach et al., 1991; Goldberg, 1993; Livingstone and Helsper, 2008; Livingstone et al., 2015a; Iqbal, 2019; Iqbal et al., 2021).\nFuture research is also welcome to examine, validate, and test the relationship between the predictors of the proposed framework of parental internet mediation for a more in-depth understanding. Further, researchers may also extend the proposed socio-ecological framework, integrating innovative approaches and related predictors.\nConclusion\nParents remain highly concerned of online behavior of children and teenagers for multiple reasons and apply mixed or diverse dimensions of internet mediation, i.e., active co-use, restrictive, monitoring, technical, internet safety mediation, or no mediation. The preference of parents for selecting multiple dimensions of mediation or no mediation is subject to their socio-economic conditions (age, education, employment status, job nature, and income), own use of the internet (time spent online and types of online activities), digital skills, and the level of communication with children/teenagers (positive, neutral, and negative). Further, the perception of parents related to threat appraisal of children/teenagers about online risks (severity and susceptibility) as well as the perception about coping appraisal of children/teenagers to perform optimal protection behaviors (response-efficacy and self-efficacy) also determine their preference for parental internet mediation. Parental internet mediation facilitates building critical thinking and nurturing resilience among children and teenagers to manage online risks and ensure online safety. Therefore, it is a prerequisite to explore the positive personality traits of children and teenagers (extrovert, emotionally stable, agreeable, conscientiousness, and openness to experiences), less disruptive behaviors (depression or anxiety, self-esteem, aggression, delinquency, or the use of drugs/smoke), and access to social resources (the support from parents, peers/friends, teachers, and community). The socio-ecological approach also suggests in considering the contextual factors of parental internet mediation, e.g., place of residence, socio-economic conditions of families, and cultural values, beliefs, and customs. A graphical illustration of the potential socio-ecological predictors is given in Figure 4.\nTo sum up, this contribution argues that parental internet mediation is an ongoing process, where parents reassess and readjust their dimensions of internet mediation based on the feedback and reaction of children and teenagers with an ultimate intention to build a strength-based outcome of resilience among them. Therefore, this theoretical review is an attempt to enrich the sociological inquiry of parental internet mediation using a multi-grounded theoretical approach. We want to enrich the academic discourse and reflect on the varied theoretical stances to explore the potential predictors of parental internet mediation. The proposed extended theoretical framework facilitates to provide an insight to comprehend the predictors of parental internet mediation more concisely, at the levels of parents, children/teenagers, and contexts, particularly highlighting resilience as a positive adjustment among children and teenagers against challenges or online risks in the context of digital media. This analytical perspective considers both psychological and behavioral predictors of parental internet mediation to adopt a resilient pathway.\nAn essential contribution of this study is related to its objective, acknowledging the need for an overarching framework of parental internet mediation in the context of a digital media-rich environment. Subsequently, this study presents an extended and a comprehensive socio-ecological framework for parental internet mediation. Future research is needed to empirically test this extended model in various settings.\nAuthor Contributions\nSI: conceptualization, investigation, and writing – original draft preparation. RZ and FF: supervision and writing – review and editing. All authors contributed to the article and approved the submitted version.\nConflict of Interest\nThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.\nAcknowledgments\nWe acknowledge support from the German Research Foundation (DFG) and the Open Access Publication Fund of Charité–Universitätsmedizin Berlin.\nReferences\nAchenbach, T. M., Howell, C. T., Quay, H. C., and Conners, C. K. (1991). National survey of problems and competencies among four- to sixteen-year-olds: parents’ reports for normative and clinical samples.\nMonogr. Soc. Res. Child Dev. 56, 1–131. doi: 10.2307/1166156\nBiernesser, C., Sewall, C. J. 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Predictors of parental mediation in teenagers’ internet use: a cross-sectional study of female caregivers in Lahore, Pakistan.\nBMC Public Health 21:317. doi: 10.1186/s12889-021-10349-z\nJohn, A., Glendenning, A. C., Marchant, A., Montgomery, P., Stewart, A., Wood, S., et al. (2018). Self-harm, suicidal behaviours, and cyberbullying in children and young people: systematic review.\nJ. Med. Internet Res. 20:e129. doi: 10.2196/jmir.9044\nKawabe, K., Horiuchi, F., Ochi, M., Oka, Y., and Ueno, S. (2016). Internet addiction: prevalence and relation with mental states in adolescents.\nPsychiatry Clin. Neurosci. 79, 405–412. doi: 10.1111/pcn.12402\nKawabe, K., Horiuchi, F., Oka, Y., and Ueno, S. I. (2019). Association between sleep habits and problems and internet addiction in adolescents.\nPsychiatry Investig. 16, 581–587. doi: 10.30773/pi.2019.03.21.2\nLin, L., Liu, J., Cao, X., Wen, S., Xu, J., Xue, Z., et al. (2020). Internet addiction mediates the association between cybervictimization and psychological and physical symptoms: moderation by physical exercise.\nBMC Psychiatry 20:144. doi: 10.1186/s12888-020-02548-6\nLin, M.-H., Vijayalakshmi, A., and Laczniak, R. (2019). Toward an understanding of parental views and actions on social media influencers targeted at adolescents: the roles of parents’ social media use and empowerment.\nFront. Psychol. 10:2664. doi: 10.3389/fpsyg.2019.02664\nLivingstone, S., Mascheroni, G., Dreier, M., Chaudron, S., and Lagae, K. (2015a).\nHow Parents of Young Children Manage Digital Devices at Home: The Role of Income, Education and Parental Style. London: EU Kids Online.\nLivingstone, S., Ólafsson, K., Helsper, E. J., Lupiáñez-Villanueva, F., Veltri, G. A., and Folkvord, F. (2017). Maximizing opportunities and minimizing risks for children online: the role of digital skills in emerging strategies of parental mediation.\nJ. Commun. 67, 82–105. doi: 10.1111/jcom.12277\nMenard, P., Warkentin, M., and Lowry, P. (2018). The impact of collectivism and psychological ownership on protection motivation: a cross-cultural examination.\nMotivation 75, 147–166. doi: 10.1016/j.cose.2018.01.020\nPaulus, F. W., Ohmann, S., von Gontard, A., and Popow, C. (2018). Internet gaming disorder in children and adolescents: a systematic review.\nDev. Med. Child Neurol. 60, 645–659. doi: 10.1111/dmcn.13754\nRogers, R. (1983). “Cognitive and psychological processes in fear appeals and attitude change: a revised theory of protection motivation,” in\nSocial Psychology: A Sourcebook. eds. J. Cacioppo and R. Petty (New York: Guilford Press), 153–176.\nStenseng, F., Hygen, B. W., and Wichstrøm, L. (2020). Time spent gaming and psychiatric symptoms in childhood: cross-sectional associations and longitudinal effects.\nEur. Child Adolesc. Psychiatry 29, 839–847. doi: 10.1007/s00787-019-01398-2\nSt. Peters, M., Fitch, M., Huston, A. C., Wright, J. C., and Eakins, D. J. (1991). Television and families: what do young children watch with their parents?\nChild Dev. 62, 1409–1423. doi: 10.1111/j.1467-8624.1991.tb01614.x\nSymons, K., Ponnet, K., Emmery, K., Walrave, M., and Heirman, W. (2017). A factorial validation of parental mediation strategies with regard to internet use.\nPsychol. Belg. 57, 93–111. doi: 10.5334/pb.372\nTruglio, R., Murphy, K., Oppenheimer, S., Huston, A., and Wright, J. (1996). Predictors of children’s entertainment television viewing: why are they tuning in?\nJ. Appl. Dev. Psychol. 17, 475–493. doi: 10.1016/S0193-3973(96)90012-X\nTwenge, J. M., and Martin, G. N. (2020). Gender differences in associations between digital media use and psychological well-being: evidence from three large datasets.\nJ. Adolesc. 79, 91–102. doi: 10.1016/j.adolescence.2019.12.018\nWHO (World Health Organization) (n.d.). Adolescent Health. World Health Organization. Available at: https://www.who.int/southeastasia/health-topics/adolescent-health (Accessed October 23, 2020).\nWright, J. C., St. Peters, M., and Huston, A. C. (1990). “Family television use and its relation to children’s cognitive skills and social behavior,” in\nTelevision and the American Family. ed. J. Bryant (Hillsdale: Lawrence Erlbaum Associates), 227–252.\nWyman, P. A., Sandler, I., Wolchik, S., and Nelson, K. (2000). “Resilience as cumulative competence promotion and stress protection: theory and intervention,” in\nThe Promotion of Wellness in Children and Adolescents. eds. D. Cicchetti, J. Rappaport, I. Sandler, and R. P. Weissberg (Washington: Child Welfare League of America), 133–184.\nKeywords: digitalization, internet addiction, theory, resilience, children, teenager\nCitation: Iqbal S, Zakar R and Fischer F (2021) Extended Theoretical Framework of Parental Internet Mediation: Use of Multiple Theoretical Stances for Understanding Socio-Ecological Predictors.\nFront. Psychol. 12:620838. doi: 10.3389/fpsyg.2021.620838\nEdited by:Gian Marco Marzocchi, University of Milano-Bicocca, Italy\nReviewed by:Pilar Lacasa, University of Alcalá, Spain\nCristina Ponte, New University of Lisbon, Portugal\nCopyright © 2021 Iqbal, Zakar and Fischer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.\n*Correspondence: Florian Fischer, florian.fischer1@charite.de", "pred_label": "__label__POS", "pred_score_pos": 0.6153087615966797} +{"content": "Court Rejects Insurer's Interpretation of its Own Policy Language on Limitations Period\nIn\nSpina v. Metro. Life Ins. Co., 2021 U.S. Dist. LEXIS 114887, (D.N.J. June 21, 2021), the court rejected both an insurer's and insured’s interpretation of when proof of loss was due under a long-term care policy and ultimately held that a lawsuit challenging a benefits denial is not time-barred by the limitations period imposed by the policy.\nDante Spina was insured under a long-term care insurance policy issued by Metropolitan Life Insurance Company (MetLife). In the spring of 2014, Spina continually moved between a nursing home, a hospital, and a rehabilitation facility, having been diagnosed with several serious medical conditions. On May 24, 2014, Spina submitted a claim under the MetLife policy, seeking benefits dating back to his first hospital stay on May 10, 2014. MetLife denied the claim after surveillance showed Spina driving a tractor and working when he claimed to be unable to perform at least two activities of daily living without assistance.\nSpina sued MetLife in state court on August 5, 2020, and the case was subsequently removed to a New Jersey district court. MetLife moved to dismiss Spina's complaint on the grounds that he had violated the subject policy's contractual limitations period. The applicable provision stated \"[n]o legal action…may be brought after six (6) years from the time written proof of claim is required to be given\" and that the policyholder \"must submit written proof of claim no later than ninety (90) days after the day You are requesting benefits.\"\nMetLife argued that because Spina claimed to be entitled to benefits starting on March 10, 2014, Spina had until June 8, 2014 (i.e., 90 days) to submit proof of the claim and until June 8, 2020 (six years) to file the action. Following this methodology, Spina filed the action approximately two months late.\nSpina countered that the provision required him to file a written proof of claim within 90 days of the last day\nfor which he was claiming benefits. Because Spina claimed entitlement to benefits through at least June 2014, he claimed the six years and 90-day period began running on that date. This methodology would have pushed his filing deadline to September 2020, and his complaint would have cleared the deadline by approximately one month. Spina also argued that the contractual limitations period conflicted with New Jersey's statutory limitations period.\nThe court rejected the argument of both sides. Preliminarily, the court upheld the validity of the limitations period in the MetLife policy, holding that New Jersey law allows for parties to contract for a limitations period shorter than the one specified by statute. Regarding the policy language, the court held that \"90 days after the day You are requesting benefits\" requires a claimant to submit proof of loss 90 days after he or she\nsubmits a claim for benefits. Because Spina submitted his claim on May 24, 2014, he had until August 22, 2014, to provide the written proof of claim and until August 22, 2020, to file the lawsuit. Accordingly, the court held that the plaintiff timely filed his claim by more than two weeks.\nIn so holding, the court stated that \"both parties have overlooked the plain and ordinary meaning of the provision in question.\"\nApplying the plain meaning, the court interpreted the provision to mean that the Spinas were required to submit a written proof of claim\nwithin ninety days of the day they submitted their request for benefits. Therefore, if the Spinas submitted their benefits claim on May 24, 2014, they had until August 22, 2014, to submit a written proof of claim and until August 22, 2020, to bring their claims without being time-barred.\nThus, the court denied MetLife's motion to dismiss on the basis of the contractual limitations bar.", "pred_label": "__label__POS", "pred_score_pos": 0.9046344757080078} +{"content": "Approximately 1 in 1800 pregnancies is complicated by adnexal torsion, typically between the sixth and fourteenth weeks of gestation. This increased frequency in pregnant women is likely due to greater laxity of the tissues adjoining the ovaries and oviducts during pregnancy, as well as to enlargement of the ovary in early pregnancy secondary to the corpus luteum cyst.\nDetorsion of the adnexa during pregnancy has not been found to compromise fetal well-being. However, if the corpus luteum cyst is removed during salpingo-oophorectomy, supplemental progesterone is indicated.", "pred_label": "__label__POS", "pred_score_pos": 0.9981706738471985} +{"content": "The European Union: Challenges and Strategic Choices\nWith 28 member states and nearly half a billion residents, the European Union has grown into a major political and economic actor on the world stage. It has promoted peace in Europe for over five decades, changed the way Europeans live, as well as the way the rest of the world perceives Europe. The EU has been considered a paradigm of a successful “peace project” that promoted stability, prosperity and successful cooperation between erstwhile feuding nations. The fact that the Union has grown from its original 6 members to the current 28 serves as undeniable proof of the appeal and attractiveness of the EU for most countries on the European continent.\nThe ongoing economic crisis in the eurozone has changed this idyllic picture of the EU: in this context, the European Union is being called upon to respond to the challenge of the economic crisis and safeguard the common currency, while promoting direct policies for confronting the recession and employment by stimulating growth. Moreover, the EU must address crucial social issues such as growing disillusionment with the European project, the rise of extremism in Europe, and growing polarization between North and South. At the same time, the EU also faces important international challenges, such as the situation in the Middle East and Ukraine, relations with Russia and the United States, and the crucial issue of energy supplies to the Union in light of the volatile international situation.\nThrough a combination of lectures, critical analysis in class discussions and students’ written work/independent research, this course will focus on the study of the history, institutions, policy processes and current challenges of the European Union. Special emphasis will be placed on the ongoing economic crisis in the eurozone area and its political/social repercussions, the strategic choices for emerging from the crisis, and the challenges of the increasingly unpredictable international environment.", "pred_label": "__label__POS", "pred_score_pos": 0.5271824598312378} +{"content": "According to the recently released data from the Bank of Greece, July revenues were 61.4% in relation to the revenues of the corresponding month of 2019. This reinforces forecasts that total tourism revenues for the year could exceed 10 billion or even close to 12 billion, according to estimates by some market participants, including former SETE president Andreas Andredis.\nAccording to the ΤτΕ (Bank of Greece), tourism revenues were 2.275 billion in July and 3.702 billion euros in 2019. To make everyone realize how big the difference is, suffice it to note that in July last year, revenue was $ 678 million.\nFor the period January-July 2021, total revenue amounted to 3.38 billion against 9.11 billion in the corresponding period of 2019 and 1.41 billion last year. That is, the revenue for 7 months corresponds to 37% of the figure for 2019.\nIn 7 months, the arrivals of travelers increased by 51.4% (by 139.7% compared to the same period in 2020), amounting to 37.1% of the indicator for 2019.\nIn July, the number of traveler arrivals and related revenues increased significantly (by 240.2% and 235.6%, respectively) compared to the same month in 2020.\nIt should be noted that this year, due to restrictions due to the pandemic, in fact, the first month of tourism was July.", "pred_label": "__label__POS", "pred_score_pos": 0.8863444328308105} +{"content": "How Does IVD Registration Process Change with New EU Regulations?\nManufacturing of in-vitro diagnostic devices (IVD) is set to change with new regulations set by the European Union (EU). According to the recent update in the EU Regulation 2017/746, medical device manufacturers are likely to face several changes in the IVD registration process. This major update brings forth more compliance to the regulatory framework for IVD manufacturers under the EU. Registration of IVDs is expected to become more modernized under this new European regulatory system.\nWhat is IVD registration?\nBefore understanding how the new IVD registration process is changing, let’s explore the process before the EU regulatory update. In the field of In-vitro Diagnostics, medical device manufacturers need to follow a process for the commercialization of IVD devices. In most healthcare markets, including the EU medical device market, manufacturers are required to follow a registration framework to get necessary approvals from the regulators.\nThis IVD registration process primarily involves obtaining the European CE Marking certification for IVD products. To get this approval, IVD manufacturers demonstrate the compliance of their products with the In Vitro Diagnostics Directive IVDD 98/79/EEC during the registration process.\nNew Changes in IVD Registration\nWith the recent EU regulatory update, IVD registration is set to undergo several changes. From regulatory documentation improvements to IVDR product registration outside of EU and EEA, these changes are being addressed to all IVD manufacturers and economic operators around the world.\nFrom early-2022, the EU will enforce new rules to redefine IVDs at pre-approval and post-approval stages of the registration. Here are some key changes in the IVD registration process:\nMedical device manufacturers can such as epilation lasers and cosmetic products such as contact lenses in the IVD category. This helps the manufacturers to expand their product lines and register more products for regulatory approvals. include non-medical products are also covered in the new IVD registration process. These IVD tests can be registered under patient therapeutics during approvals. Genetic test kits New rules require IVD manufacturers to of the process. Their experimental IVD products need to pass various levels of safety through effective evidence before getting approved for widespread use. demonstrate clear and higher evidence during the experimental stage These new changes also affect the production of existing IVD products. Hence, manufacturers are compelled to seek . This emerges as a key challenge for most medical device manufacturers. If an existing IVD product fails the registration process during recertification, it can entail economic losses through product recalls. recertification of existing IVD products Why is this New IVD Registration Important?\nThe new changes in IVDR aim to address concerns such as end-user transparency and patient safety. IVD markets are likely to be influenced by these increased expectations for clinical evidence. Under strict scrutiny, manufacturers will need to maintain and provide more data to competent authorities and notified regulatory bodies. The traceability of these products throughout the supply chain is also crucial under the new changes in the IVD registration process. The EU is also stepping up its safety monitoring through different stages of quality control and assurance. Going forward, this will emerge as a new regulatory task for IVD manufacturers in the EU and outside.", "pred_label": "__label__POS", "pred_score_pos": 0.7114419937133789} +{"content": "The national average retail price of a gallon of diesel climbed for the sixth consecutive week, rising 7.4 cents to $2.572 for the week ending Monday, June 15. However, the price — which has climbed 38.7 cents in the last six weeks — is still $2.120 less than the same week last year, according to the U.S. Department of Energy.\nAll regions tracked by DOE saw price increases. The largest increase by region, 8.8 cents, was found in the Lower Atlantic, where week-over-week prices climbed to $2.556. The smallest increase by region, 5.2 cents, was found on the West Coast, where week-over-week prices rose to $2.655.\nThe nation’s most expensive diesel by region, $2.696, was found in the Central Atlantic region, where prices climbed 7.7 cents. The nation’s least expensive diesel by region, $2.520, was found in the Rocky Mountains, where prices climbed 7.8 cents.\nCalifornia, which DOE tracks separately for its weekly update, saw a price increase of 5.8 cents to $2.734; however, that price is $2.235 cheaper than last year. For state-by-state diesel prices, updated daily, click here.", "pred_label": "__label__POS", "pred_score_pos": 0.961643636226654} +{"content": "Abstract\nState-of-the-art 3D morphable model (3DMM) is used widely for 3D face reconstruction based on a single image. However, this method has a high computational cost, and hence, a simplified 3D morphable model (S3DMM) was proposed as an alternative. Unlike the original 3DMM, S3DMM uses only a sparse 3D facial shape, and therefore, it incurs a lower computational cost. However, this method is vulnerable to self-occlusion due to head rotation. Therefore, we propose a solution to the self-occlusion problem in S3DMM-based 3D face reconstruction. This research is novel compared with previous works, in the following three respects. First, self-occlusion of the input face is detected automatically by estimating the head pose using a cylindrical head model. Second, a 3D model fitting scheme is designed based on selected visible facial feature points, which facilitates 3D face reconstruction without any effect from self-occlusion. Third, the reconstruction performance is enhanced by using the estimated pose as the initial pose parameter during the 3D model fitting process. The experimental results showed that the self-occlusion detection had high accuracy and our proposed method delivered a noticeable improvement in the 3D face reconstruction performance compared with previous methods.\nBibliographical noteFunding Information:\nThis work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (No. 2012–0005223).\nAll Science Journal Classification (ASJC) codes Signal Processing Hardware and Architecture Electrical and Electronic Engineering", "pred_label": "__label__POS", "pred_score_pos": 0.9966097474098206} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis report summarizes survey data collected in 2020, both before and during the pandemic; it is the fourth survey, preceded by findings from 2004, 2009, 2014.\nThe Afterschool Alliance's webpage on COVID-19 offers a rich array of resources to help support Out-of-School Time (OST) system builders, administrators, and practitioners in navigating the challenges of the pandemic as they strive to effectively serve children, families, and providers.\nThe Office of Inspector General's issue brief identifies a concern that if states set payment rates too low, families may not have access to child care providers.\nThis blog is the second part in a series on prevention and responding to substance use and trauma in Alaska. It describes a collaborative effort and training on trauma-engaged response.\nThis issue brief provides a succinct overview of social emotional learning and why afterschool is a perfect place to focus on this and to achieve positive developmental outcomes. It includes examples of curriculum and activities for afterschool programs from SC, NC, GA, NH, and NY.\nThis brief provides a crosswalk of three common community supports that enhance children's social and emotional health: (1) infant and early childhood mental health consultation, (2) pyramid model/practice-based coaching, and (3) mental health treatment. It provides information such as definitions, professional qualifications, and service examples.\nThis policy statement provides recommendations from the U.S. Department of Health and Human Services (HHS) for developing and implementing career pathways to support the professional learning, practice, and compensation of early childhood educators and program directors.\nThis website offers resources on a range topics related to healthy youth development, with the goal of helping users create, maintain, and strengthen effective youth programs.\nThe Afterschool Alliance has developed an easy-to-use searchable database on evidence-based impacts of afterschool and summer programs.\nThis report summarizes 2014 survey results and provides a quick picture of supply and demand in afterschool. It indicates that the numbers of children being served in afterschool have increased to 10.2 million. It also indicates that the numbers of children that would enroll if a program were available is increasing to 19.4 million.", "pred_label": "__label__POS", "pred_score_pos": 0.8059976100921631} +{"content": "Know Your Customer (KYC) regulations have evolved and expanded rapidly, and for good reason. When a cybercriminal can purchase an identity for just over $1,000 on the dark web, consumers and businesses are at significant risk of fraud.\nThe dramatic rise in cybercrime during the pandemic led to swift regulation enforcement, a key example being the early institution of 6AMLD. Going forward, we’re likely to see even more extensive security measures take over.\nFor real estate financing, a key issue has been how to implement these safeguards. The fact is, traditional KYC processes are not only insufficient but expensive. Meanwhile, companies are shifting through numerous solutions in an attempt to transform their company operations for the digital era.\nBefore we get to potential solutions, it’s critical to understand why traditional processes, even when digitized, are no longer an option for most firms.\nThe problem with traditional KYC processes\nTraditional KYC processes are a significant revenue and time leak. Offline procedures that rely on customer print-outs and documentation copies require digitization and significant resources. All of this delays onboarding.\nBut most online processes don’t fare much better. Many digital KYC processes still require manual data entry, verification, and approvals.\nAt the same time, KYC regulation has continued to become more complex. The mismatch of legacy systems with complicated compliance processes has created bottlenecks and inefficiencies and organizations scramble to remediate their process.\nBut KYC operations, especially for real estate financing and investment, suffer from more than inconsistency. When conducting due diligence with KYC/KYB operations, businesses have to consider data security, user privacy, sort through redundancies, and keep updated files on record.\nFailing to do so results in higher risk for everyone involved in a real estate transaction. At the same time, the cost of maintaining secure systems is quickly becoming unsustainable. The cost of KYC compliance has dramatically increased the cost of onboarding clients, which averages at about $6,000.\nWe can see that the traditional process is no longer sustainable. And technology offers us a solution.\nKYC on the Blockchain\nWhile initially used as a ledger for payments, blockchain technology provides the optimal platform for KYC compliance. Built through advanced cryptography, blockchain technology offers a transparent and secure engine for any transaction.\nInformation exchanged during a transaction – such as KYC data – is compiled and logged within a block. Once that block is attached to the previous block, it cannot be changed. This feature alone provides an auditable, secure method of maintaining records. The process of creating a block, completed through mathematical equations, is also incredibly fast.\nIt’s also important to note that many actions can take place automatically on the blockchain, especially if a platform uses smart contracts. Smart contracts are essentially a set of conditions that, once fulfilled, automatically take action. These capabilities take the place of costly intermediaries, which further complicate and slow down the KYC process.\nIn other words, with blockchain technology, it’s possible to automate the KYC process and decrease onboarding times without sacrificing security or compliance measures.\nFinding a KYC Compliant Blockchain Platform\nSo, how do you find a blockchain-based platform that makes sense for your business? While there aren’t many in the real estate financing space, more and more startups are popping up, with varying features. Ultimately, you’ll want a platform that provides secure and tested tools for investors to manage their own KYC data and identity profile when investing in real estate digitally.\nAt Earn, we have a user-friendly complaint onboarding process that makes it easy to verify and monitor customer and business information. Some features include:\nEstablishing and maintaining compliant investor profile(s). Populating each profile with adequate data to ensure compliance for all parties. Associating profile data with the investor’s unique blockchain id, also known as their wallet. Streamlining subscription and allocation processes using pre-established investor profiles. Storing information securely and allowing the investor to subscribe to multiple offerings in the future.\nIn the best-of-class platforms, you will be able to cut out redundancies as investors only need to input their data once. Once saved on the platform, investors have complete control over their personal information from their unique and secure wallets. At the same time, our systems can verify information through the blockchain ledger without pulling sensitive information. Instead, our system sees a tokenized version of the data that is useless to potential malicious parties.\nBecoming future-ready\nA solid KYC platform is essential for the future of real estate investing. Slow and inefficient onboarding is not only expensive, but it will turn away customers. And these manual processes are increasingly becoming more susceptible to fraud.\nBlockchain technology can streamline KYC processes, secure client data, and make it easier than ever to stay ahead of the curve.\nOur platform has been tried and tested by industry leaders. To learn more, book a demo with us today.", "pred_label": "__label__POS", "pred_score_pos": 0.763681173324585} +{"content": "Test Relays Accurately with the ISA T-1000 Relay Test Set\nUncategorized\nRelays have a high risk of unexpected failures because of the constant switching of high currents. The constant switching puts severe electrical and mechanical stress on the contacts. After a while, it may fail and disrupt normal operations. Technicians must evaluate the reliability of the electrical system’s relays to avoid hassles.\nThe ISA T-1000 is a powerful tester that offers multi-relay type testing capabilities. It has its own 3 separate generators for phase shift-able AC voltage, AC current and DC voltage. You can adjust the outputs, and they are monitored real-time on its LCD screen. This lets you customize the generators depending on the test you are conducting. This relay test set has semi-automatic and manual testing modes to suit your preferences. The test results can be transferred to a computer through its USB or RS232 ports. This lets you further analyze the test results using its powerful TDMS software.\nPrevent unexpected electrical failures through regular preventive maintenance. You can rent the tools you need from\nProtec Equipment Resources. We have affordable rental plans to suit your needs. You can reach a Protec advisor at 1-866-352-5550 for any questions about our services.", "pred_label": "__label__POS", "pred_score_pos": 0.9337235689163208} +{"content": "To ask the Secretary of State for Work and Pensions, what recent assessment he has made of the potential merits of introducing a secure alternative to the Post Office Card Account (POca) card for those without a bank account, which offers face-to-face support for those requiring assistance.\nAnswered on\n8 September 2021\nWe recognise that not all of our customers are able to open and operate standard accounts, which is why we offer an alternative for those customers.\nThe Post Office card account (POca) contract is due to end and the Department plans to start moving customers to the replacement Payment Exception Service (PES) during the coming months.\nThe new PES is similar to Her Majesty’s Government Payment Exception Service (HMG PES) which has been in place since 2018 and is due to end in September 2021. The HMG PES service has successfully served our most vulnerable customers by the issue of vouchers which are uploaded to a card or sent electronically via SMS or email.\nThe replacement PES has also been designed for customers who cannot open or manage a basic bank or standard account. We have ensured that the new service enables users to continue to obtain cash payments in their local area (including suburban and rural locations) following the end of the Post Office card account contract.\nCustomers identified as at risk of harm will receive additional support before being migrated to the new service. This includes outbound calls to make contact with the customer or their nominated representative and referral to the DWP visiting service to make face-to-face contact where a call is unsuccessful or identifies that a visit is required. Post migration we will track the encashment of vouchers by all customers to ensure that they are accessing the payments they receive at the level we would expect. This post migration support is significantly stronger than currently exists for POca.", "pred_label": "__label__POS", "pred_score_pos": 0.6500237584114075} +{"content": "Each year, April 7 marks World Health Day. With the past year marked by the global struggle against COVID-19, the occasion has never been more significant. The pandemic’s impact has been devastating and swift; not one person or nation has escaped its effects. In particular, health systems have struggled to meet demand for services while keeping patients and providers safe.\nNurses comprise the largest proportion of Canada’s health care providers. The most recent data from the Canadian Institute for Health Information (CIHI)’s Nursing in Canada, 2019 survey reveals that the regulated nursing workforce grew by 1.9 per cent from 2018: faster than the general Canadian population growth. This increase is welcome news, since nurses play a prominent role in patient care. A larger nursing workforce will support better access to health care for Canadians, especially during this unprecedented health crisis.", "pred_label": "__label__POS", "pred_score_pos": 0.8350180387496948} +{"content": "By Barbara O’Neill. Published on Egyptological, In Brief, August 14th 2012 Introduction: An Overview of the Mortuary Temple\nIn the Old and Middle Kingdoms, pyramid complexes incorporated a mortuary chapel where cult to sustain the deceased king could be maintained. By the Eighteenth Dynasty however, the royal-mortuary temple had evolved from an integrated part of the burial complex adopting a more fragmented form within discrete structures at western Thebes. The mortuary temple’s layout was closely based upon that of contemporary divine-cult temples. Typically, a royal mortuary temple included the following elements:\nan axial sanctuary for the barque of Amun-Ra; an open court for worship of the sun-god; at least one false door for the presentation of offerings, and a location for the commemoration of royal ancestors.\nTemple organisation evolved and changed through time, with cults for the living or deceased kings not restricted to mortuary temples, (Gundlach, 2009; Arnold, 1997).\nThe Mortuary Complex at Abydos\nRe-excavation work, carried out by Dr. Stephen Harvey between 1993-2006 at the mortuary complex of Nebpehtyre Ahmose (King Ahmose I) at Abydos, has provided renewed insight into the conceptual variability of intended functions within divine and mortuary cults, following the reunification of Egypt at the beginning of the New Kingdom (Harvey, 1998). With no evidence of a mortuary temple for this monarch at Thebes, the vast mortuary complex constructed by Ahmose at South Abydos, includes subsidiary structures for his sister-wife Ahmose-Nefertari and their grandmother Tetesheri, with other cult-components possibly related to Crown Prince Ahmose, an eldest son, who is believed to have predeceased his father.\nConstruction of his mortuary complex is believed to have begun late in Ahmose’s reign between Regnal Years 18-22 following his defeat of the Hyksos, an event recorded on the outer walls of his pyramid temple at Abydos and attested through thousands of carved relief and painted fragments. Triumphant battle-scenes depicting horses and chariots, perhaps the earliest examples of this genre, provide ‘unique historical data’ which may prompt a revision of our understanding of the chronology of narrative art in Egypt (Harvey, 1998-p.150; O’Connor, 2009, p108). Other innovative elements include stamped bricks, the first ever attested in a royal-mortuary complex. The bricks indicate a revised titulary for Ahmose as\nSa-rA-HqAtAwy, and HqAtAwy-mry-Wsir uniting this king with the mortuary-cults of both Re and Osiris.\nAlthough most of Ahmose’s funerary structure at Abydos no longer exists in an immediately recognisable form, Dr. Stephen Harvey’s painstaking work has revealed evidence of the massive structure which once stood there. Constructed along a central north-south axis at South Abydos, the complex included a large mortuary temple at the edge of the arid area close to the limit of cultivation, with the subsidiary temple of Ahmose-Nefertari nearby. There is evidence of tree-pits either side of the main temple’s northern entrance which was approached through a massive mud-brick pylon gateway which itself stood before open courts. Within the temple, the pillars of colonnaded halls bore scenes depicting Ahmose in the embrace of several deities. Other carved and painted imagery (now fragmented) attests to an evident preoccupation with offering table scenes within which Ahmose-Nefertari stands behind the king, who is seated before elaborate offerings, served by\niwnmwtf priests. In this imagery, the king is clearly the object of cultic devotion (Harvey, 1998).\nAt the beginning of the Eighteenth Dynasty significant changes occurred in divine cult and royal mortuary temple ideology. Interpreting the repertoire of scenes and the use of cultic space within Ahmose’s temple is important In understanding these changes. Enactment of ritual evolved from that carried out on behalf of the deceased king, to cultic practices carried out by the king on behalf of the gods. Depictions within the South Abydos temple complex and at his Northern shrine portray Ahmose as the object of cult signifying his divine nature and suggesting ‘a compelling personal need’ for deification and immortality (Harvey, 1998, pp.419-421; O’Connor, 2009-p.109).\nThe pyramid temple of Ahmose is believed to have been the last monument of that type to have been built in the Nile Valley by an Egyptian king. The decision to built a pyramid temple was most likely intended to evoke the successful political and economic reigns of earlier Middle Kingdom unifier kings. Ahmose employed the monumental symbolism of pyramid and terrace temple forms succinctly integrating Memphite, Theban and Abydene funerary ideologies into the design, layout and structure of his mortuary temple. It was clearly important to Ahmose that in his most significant temple structure all important aspects of Egypt’s funerary traditions were reflected in this mortuary complex. Today Ahmose I is recognised as the founder of the 18\nth Dynasty. Living in turbulent times, it is likely that he believed adherence to traditions as either propitious or politically expedient to his ambition to reunite Upper and Lower Egypt.\nThe southern-axial placement of a nearby enclosure dedicated to Ahmose’s wife, Ahmose-Nefertari, appears to indicate her cultic role as an incarnation of Hathor, signifying the prominent role of his sister-wife during Ahmose’s reign. Further on from the pyramid complex is a shrine dedicated to Tetesheri placed close to her unfinished cenotaph-tomb. This part of the complex culminates in a terraced temple built into the cliffs which surround the area.\nThe elevated terrace temple may represent the\nrwd-nTr-aA, the staircase of Osiris, with the related tomb symbolising the Osirian cave and the sacred grove which surrounded it. The pyramid and its subsidiary structures appear to represent the Axt, the solar horizon, conceptualising Dt-Osirian time of permanent perfection and cyclic nHH-time, related to solar renewal. Although Osirian ideology was an overarching factor in Ahmose’s funerary programme, solar aspects are also evident in the east-west axis of the complex, referencing Memphite-style solar iconography through the pyramid which dominated the eastern end of the monumental axis; its form representing the primeval mound of creation.\nAhmose has two physically separate cult locales at Abydos. At North Abydos, within the Osiris temple complex, Amenhotep I also built a cult chapel for his father where Ahmose’s Osirian transformation appears paramount. There is evidence that both locales were connected through ritual procession (Harvey, 2011). This conclusion is supported by depictions of the Ahmose barque within the temples of Ramesses II and Seti I nearby.\nConclusion\nThe mortuary complex of Nebpehtyre Ahmose has ‘paradigmatic and extra-regional significance’ in the development of royal cult from the start of the Eighteenth Dynasty, (O’Connor, 2009, p.107). This is also evident in the newly emergent cult of the royal-ka, as exemplified within the Theban temples of Amun-Ra at Karnak and Luxor, and within the Southern and Northern mortuary structures of Ahmose at Abydos. Modifications created by Ahmose within post-Hyksos Egyptian royal funerary ideology is said to have profoundly affected the rest of the Eighteenth dynasty (Bryan, 2000).\nIt was once noted that the reign of Ahmose lacked the time and resources for significant construction, with his finest ‘monument’, the Eighteenth Dynasty itself, (Lefebvre, 1929 in Harvey, 2007). However, it might be argued that the unique legacy emerging from ongoing investigations into this king’s intriguing mortuary complex at Abydos, indicates significant architectural and theological innovations which may have influenced royal and divine-cult ideologies from the dawn of the New Kingdom.\nBibliography\nArnold, D., 1994, ‘\nThe Encyclopedia of Ancient Egyptian Architecture’, English Language Edition, 2003, New York, Princeton University Press.\nArnold, D. 1997, ‘Royal Cult Complexes of the Old and Middle Kingdoms’ in B. Shafer, et al eds., ‘\nTemples of Ancient Egypt’, New York, Cornell University Press\nBryan, B., 2000, ‘The 18\nth Dynasty before the Amarna Period, (c.1550-1352 BC), in I. Shaw, ed., ‘ The Oxford History of Ancient Egypt’, Oxford, OUP\nGundlach, R. 2009, ‘Horus in the Palace’, in R. Gundlach and J. Taylor, eds., ‘\nEgyptian Royal Residences’, 4th Symposium on Egyptian Royal Ideology, Wiesbaden, Harrassowitz Verlag\nHarvey, S., 1998, ‘\nThe Cults of King Ahmose at Abydos’, Dissertation, Ann Arbour, UMI 9829912\nHarvey, S., 2007, ‘King Heqatawy: Notes on a Forgotten Eighteenth Dynasty Royal Name’ in Z. Hawass, J. Richards ‘\nThe Archaeology and Art of Ancient Egypt: Essays in Honor of David B. O’Connor, Volume II’, Cairo, AUC Press\nO’Connor, D. 2009, ‘\nAbydos: Egypt’s First Pharaohs and the Cult of Osiris’, London, Thames & Hudson Ltd. Image Credits\nFigures 1,2 – Adapted by Kate Phizackerley from originals by GDK, licensed under Creative Commons Attribution Sharealike 3.0\nFigure 3 – By JMCC1 via Creative Commons Attribution 2.0 Generic license.", "pred_label": "__label__POS", "pred_score_pos": 0.7158352136611938} +{"content": "If the duty is one which the trustee cannot properly delegate, but he delegates it nevertheless and a loss is sustained, the trustee will be absolutely liable to the beneficiaries. If a duty is delegable and the trustee used reasonable care in the delegation, selection, and supervision of the agent, but a loss was sustained because the agent acted with negligence, dishonesty, or other misconduct, the trustee is not liable to the beneficiaries. If a duty is delegated and reasonable care is used in delegation, the trustee will be liable to third parties under the doctrine of respondeat superior. However, the trustee is entitled to indemnification from the trust estate. Note: respondeat superior does not apply to independent contractors.", "pred_label": "__label__POS", "pred_score_pos": 0.9181137681007385} +{"content": "Abstract\nGenome-wide association studies (GWASs), which assay more than a million single nucleotide polymorphisms (SNPs) in thousands of individuals, have been widely used to identify genetic risk variants for complex diseases. However, most of the variants that have been identified contribute relatively small increments of risk and only explain a small portion of the genetic variation in complex diseases. This is the so-called missing heritability problem. Evidence has indicated that many complex diseases are genetically related, meaning these diseases share common genetic risk variants. Therefore, exploring the genetic correlations across multiple related studies could be a promising strategy for removing spurious associations and identifying underlying genetic risk variants, and thereby uncovering the mystery of missing heritability in complex diseases. We present a general and robust method to identify genetic patterns from multiple large-scale genomic datasets. We treat the summary statistics as a matrix and demonstrate that genetic patterns will form a low-rank matrix plus a sparse component. Hence, we formulate the problem as a matrix recovering problem, where we aim to discover risk variants shared by multiple diseases/traits and those for each individual disease/trait. We propose a convex formulation for matrix recovery and an efficient algorithm to solve the problem. We demonstrate the advantages of our method using both synthesized datasets and real datasets. The experimental results show that our method can successfully reconstruct both the shared and the individual genetic patterns from summary statistics and achieve comparable performances compared with alternative methods under a wide range of scenarios. The MATLAB code is available at:http://www.comp.hkbu.edu.hk/~xwan/iga.zip.\nOriginal language English Article number 7164310 Pages (from-to) 557-564 Number of pages 8 Journal IEEE/ACM Transactions on Computational Biology and Bioinformatics Volume 13 Issue number 3 DOIs Publication status Published - 1 May 2016 Scopus Subject Areas Biotechnology Genetics Applied Mathematics User-Defined Keywords biclustering convex optimization GWAWs low-rank and sparse SNPs", "pred_label": "__label__POS", "pred_score_pos": 0.6767811179161072} +{"content": "January 2010\nIn a lengthy decision regarding online student speech, the United States District Court for the Central District of California ruled that a student’s posting of an online video containing derogatory, sexual and profane statements about a fellow classmate did not create enough of a substantial disruption on campus to permit discipline by the school district. (\nJ.C. v. Beverly Hills Unified School Dist. (C.D. Cal. 2009) No. 08-03824.) Although the court held that the student’s online speech was protected by the First Amendment in this situation the court nevertheless recognized that a school district has the authority to regulate off-campus speech, including online speech, if the specific facts show that the speech “materially and substantially disrupted the work and discipline of the school.”\nPlaintiff was a middle school student. While at an off-campus location and after school hours, she recorded a four-minute video making fun of a fellow classmate, C.C. The video included students calling C.C. derogatory names, making sexual comments and using profanity. On the video, plaintiff was heard urging the students to continue insulting C.C. Plaintiff returned home, posted the video on YouTube, a public video website, and sent emails to approximately ten students, telling them to watch the video. Plaintiff also contacted C.C. to alert her to the video posting. By the next day, the video had already received over 100 hits and students were discussing the video on campus.\nC.C. was extremely upset and came with her mother to the school to report the video. C.C. did not want to go to class and met with a school counselor for 25 minutes because she was humiliated and hurt by the video. In response, school administrators called plaintiff from class and directed her to take the video down from the YouTube website. The district then suspended plaintiff for two days.\nPlaintiff sued the district, and three individual administrators, alleging that the district violated her First Amendment rights by disciplining her for off-campus, online speech. The court explained that there was no bright-line rule applicable to all internet speech and acknowledged that “the substantial weight of authority indicates that geographic boundaries generally carry little weight in the student-speech analysis.” In such cases, courts must apply the standard set forth by United States Supreme Court in\nTinker v. Des Moines Independent Community School Dist. (1969) 393 U.S. 503, which allows school districts to regulate off-campus speech if the speech causes or is reasonably likely to cause a substantial disruption of school activities.\nHowever, after applying Tinker to the facts of the case, the court concluded that the plaintiff’s YouTube video had not caused or threatened to cause a substantial disruption on the school campus. First, the court reasoned that plaintiff’s YouTube video did not actually disrupt school activities. Although the court acknowledged that an actual disruption need not have already occurred, it focused on the fact that the district staff had only spent a few hours addressing the concerns of an upset parent and only five students, including the student victim, had missed a minimal amount of class time in response to the video. The court also noted that there was no evidence of a “widespread whispering campaign [that] was sparked by the video [and] no students were found gossiping about C.C. or about the video while in class,” even though these were the behaviors the administrators were attempting to prevent by having the student take down the video.\nThe court emphasized that the video was unlikely to lead to actual verbal or physical conflicts between students, none of the students involved had a history of violence and there was no evidence of similar incidents causing disruptions in the past. In summary, the court concluded that a substantial disruption “must equate to something more than the ordinary personality conflicts among middle school students that may leave one student feeling hurt or insecure.”\nThe court rejected the school district’s arguments that there was a foreseeable risk of a future substantial disruption. The court explained that “undifferentiated fears or mere disapproval alone will not justify disciplining student speech” and instead, a school district must articulate specific facts suggesting a high likelihood of a future disruption. In the absence of such evidence, the court concluded that there was not a sufficient nexus between the student’s off-campus conduct and the disruptive effect on campus.\nFinally, despite holding that the school had violated the student’s free speech rights, the court dismissed the claims against the individual administrators under the doctrine of qualified immunity. Under this doctrine, the employee of the public entity may avoid personal liability if the constitutional right that was violated was not clearly established at the time of the violation. Here, because the United States Supreme Court has never addressed a school’s authority over internet speech and the only Ninth Circuit Court of Appeals case addressing the issue\nupheld the school’s regulation of speech, the school district officials had no reason to know the discipline would potentially violate the student’s rights.\nIt is important to note that student speech cases are very fact-specific. Although the court failed to find a sufficient level of disruption in this case, the court nevertheless reinforced the idea that school districts may regulate off-campus speech if the speech creates or is reasonably likely to create a substantial disruption to school activities. Therefore, school districts should proceed cautiously when disciplining students for online or other off-campus speech and should make sure to support any disciplinary action with strong evidence of any actual or potential disruption to school activities.\nShould you have questions about this case, or its impact on your school district, please contact one of our five offices.\nF3 NewsFlash prepared by Kimberly Smith and Kelley Owens. This F3 NewsFlash is a summary only and not legal advice. We recommend that you consult with legal counsel to determine how this case may apply to your specific facts and circumstances. Information on a free NewsFlash subscription can be found at www.fagenfriedman.com.\nAs part of the\nE-ducation™ Professional Development Series hosted by ACSA and F3, we offer webinars on various topics. You can find the information on the ACSA website at http://www.acsa.org/MainMenuCategories/ProfessionalLearning/E-ducation-Series.aspx.", "pred_label": "__label__POS", "pred_score_pos": 0.589552640914917} +{"content": "NEW DELHI: Union Health Minister Mansukh Mandaviya on Monday launched an initiative to facilitate COVID-19 vaccine delivery to tough and hard-to-reach terrains of the Northeast through drones.\nThe ICMR's Drone Response and Outreach in North East (i-Drone), a delivery model to make sure that life-saving COVID vaccines reach everyone, is in line with the government's commitment to Antyodaya' in health - making healthcare accessible to the last citizen of the country, officials said.\n\"This is for the first time that a \"Make in India' drone has been used in South Asia to transport COVID-19 vaccine over an aerial distance of 15 km in 12-15 mins from the Bishnupur district hospital to Loktak lake, Karang island in Manipur for administration at the PHC.\n\"The actual road distance between these locations is 26 km. Today, 10 beneficiaries will receive the first dose and eight will receive the second dose at the PHC,\" Mandaviya said.\nThanking Prime Minister Narendra Modi, the Union Health Minister said, \"Under his leadership, the nation is progressing at a great pace.\n\"Today is a historic day, which showed us how technology is making life easier and bringing social change.\"\nIndia is home to geographical diversities and drones can be used to deliver essentials to the last mile, he said.\n\"We can use drones in delivering important life-saving medicines, collecting blood samples. This technology can also be used in critical situations. This technology may prove a game-changer in addressing the challenges in health care delivery, particularly health supplies in difficult areas,\" Mandaviya said.\nLaunching the initiative which would facilitate vaccine delivery to hard-to-reach terrains of India, the Union Health Minister said, \"Our immunisation programme for COVID-19 has already exceeded all expectations.\n\"I strongly believe that this initiative will further help us achieve the highest possible immunisation coverage for COVID-19. Incorporating such drone technologies into the national programmes would help deliver other vaccines and medical supplies as quickly as possible.\"\nDespite the effective and safe vaccine administration in the states and Union Territories, the vaccine delivery in tough and hard-to-reach terrains of India is still challenging.\nThe i-Drone has been designed to overcome these challenges by deploying Unmanned Aerial vehicles (UAV) / drones to remote areas, the health ministry said.\nCurrently, the drone-based delivery project has been granted permission for implementation in Manipur and Nagaland, as well as the Union Territory of Andaman and Nicobar Islands.\nThe ICMR conducted an initial study in collaboration with the Indian Institute of Technology, Kanpur to test the capacity of drones to carry and transfer vaccines safely.\nThe study was conducted in Manipur, Nagaland and Andaman and Nicobar.\nThese studies provided promising results on the basis of which the Ministry of Civil Aviation (MoCA), Directorate General of Civil Aviation (DGCA) and other regulatory authorities have granted permission to fly drones beyond the Visual Line Of Sight.\nMandaviya expressed confidence in the initiative and noted that it can be helpful in delivering not only vaccines but also other medical supplies.\nThis will help in overcoming the gaps in current vaccine delivery mechanisms, he said He thanked the Ministry of Civil Aviation, DGCA and the Airport Authority of India for their support towards this endeavour and congratulated ICMR, health workers and all associated with this landmark initiative.", "pred_label": "__label__POS", "pred_score_pos": 0.7417685389518738} +{"content": "There is a condition affecting millions of people around the world which can be the bane of their daily life. It can lead to sufferers exhibiting a vast array of symptoms; the most commonplace being intense pain. It may not be derived from a specific accident or trauma or may not be centred on one particular part of the body. As a matter of fact, those living with Fibromyalgia may experience a cross-section of physical effects, all over.\nThere have been cases where the ailment may result from a particular injury. However, at the same time, the symptoms may gradually progress, and get worse over time, which may have a lasting, negative impact on their lives.\nIt should be noted that, as well as intense, overriding pain, other symptoms of fibromyalgia range from muscular stiffness and headaches to low energy. This also encompasses feelings of fatigue, disrupted sleep, and digestive issues such as stomach pain and IBS or irritable bowel syndrome alongside many others.\nFor years, people living with fibromyalgia have been searching for a viable treatment, which can help relieve the symptoms and ease their suffering. They may consult their GP, or take pain medications, but, in this day and age, an increasing number are considering another option, and taking CBD to overcome their condition\n.\nThey have chosen this course due to cannabidiol’s noted pain relief properties, especially considering CBD's renowned anti-inflammatory qualities. Particularly when you take into account one of the principal concerns for people afflicted with fibromyalgia is the risk of brain inflammation, which can be devastating. However, experts feel consuming CBD can reduce the possibility of developing the condition. This, alongside taking cannabidiol regularly, can help people alleviate intense pain once and for all.\nIf you live with fibromyalgia, it can feel as if you have a great deal to overcome. It can be a constant struggle, but consuming CBD daily can be the secret to easing the symptoms, which could change your life for the better.\nSource: Cbdqueen.co.uk", "pred_label": "__label__POS", "pred_score_pos": 0.8839055299758911} +{"content": "Possible involvement of IL-6-producing tissue-resident macrophages in early-onset pericardial effusion pathogenesis after hematopoietic stem cell transplantation.Hamada Satoru,Miyamoto Jiro,Oshiro Tokiko,Yagi Takeshi,Kiyuna Shinobu,Uehara Taichi,Matsuda Takehiro,Higa Takeshi,Hyakuna Nobuyuki,Nakanishi KoichiPediatric blood & cancerPURPOSE:Pericardial effusion (PE) is a potentially life-threatening complication following hematopoietic stem cell transplantation (HCT). A higher incidence of early-onset PE, unrelated to graft-versus-host disease, before day 100 after HCT has been reported in pediatric patients, but the pathogenic mechanism is poorly understood. Aiming to determine the pathogenesis of early-onset PE in pediatric patients, we analyzed the cytokine concentration and cell population in the pericardial fluid of four pediatric patients with PE. METHODS:Between January 2009 and December 2015, four patients requiring pericardiocentesis for clinically significant PE were identified in 60 patients. We evaluated the interleukin-6 (IL-6), interferon-γ, IL-1β, and tumor necrosis factor-α levels in PE. Two patients were available for analysis with intracellular cytokine flow cytometry and a chimerism assay. RESULTS:All patients showed the accumulation of pericardial macrophages and high concentrations of IL-6 in PE. Notably, the accumulated pericardial macrophages were CD163 CD15 CD14 cells of host origin that produced IL-6. CONCLUSION:These IL-6-producing tissue-resident macrophages may be key players in the pathogenesis of early-onset PE.10.1002/pbc.26982", "pred_label": "__label__POS", "pred_score_pos": 0.607769250869751} +{"content": "October 6, 2021\nThe ongoing COVID-19 pandemic continues to exhaust our energies, medical capacities and claim human lives across the world. Over the last year and a half, the healthcare system in Syria has faced enormous challenges in attempting to circumvent the spread of the virus while simultaneously facing severe shortages in equipment and qualified staff due to the decade-long conflict in the country.\nAs part of a concentrated effort to respond to the virus in Northwest Syria, SAMS has participated in efforts with other health organizations in the region to prepare isolation centers in existing hospitals specifically for COVID-19 patients. This larger effort aims to curb the spread of COVID-19, as hospitals in northwest Syria are already under strain due to equipment shortages, the constant state of emergency response, and ever-decreasing medical staff capacities. As it stands, SAMS established and operates four COVID-19 hospital-based isolation units (HBIUs), including three for adults, and one for children. The HBIUs encompass 210 beds and 90 ventilators in total. These hospitals produce more than 2,880 m3/day of Oxygen, which is equal to 720 oxygen tanks, each containing approximately 660ml of oxygen per day. Despite these efforts, this production barely covers 50% of the HBIUs’ oxygen needs.\nOxygen shortages have been experienced worldwide since the onset of the COVID-19 pandemic. Earlier this year, shortages were reported in Brazil, Lebanon and India, among other countries, which led to severe repercussions and avoidable deaths. In northwest Syria, the lack of available oxygen is particularly acute. As it stands, 3,000 out of 61,586 confirmed COVID-19 patients have been hospitalized since the onset of the pandemic. As of September 2021, admission rates to our COVID-19 treatment centres have reached full capacity, with all facilities reporting oxygen shortages. Should access to oxygen be stopped for any reason, patients face a higher possibility of death. There is also a lack of spare parts, making it difficult to repair stations that break, further increasing the level of risk facing patients in need of oxygen. The situation has worsened exponentially, as the COVID-19 death toll in September reached over 200, compared with 50 COVID-19 related deaths reported in August. Daily test positivity rates have reached 58%, a record high since the pandemic began.\nThe importance of oxygen tanks is illustrated by Khaldiyah, a 70 year-old immunocompromised patient, who was brought to SAMS’ isolation unit at Al-Amal Hospital. Khaldiyah’s situation was deteriorating rapidly upon her arrival, and her doctors were extremely worried about her survival. After carrying out an x-ray, doctors also found ground-glass opacities (the radiology term describing the appearance of fluid in the lungs on a scan) in her lungs, in addition to the immense suffering respiratory distress, acute cough,fever, and skeletal pain that Khaldiyah reported. Upon placing her on a CPAP device (a machine that uses a hose and mask or nosepiece to deliver a steady flow of oxygen), Khaldiyah’s respiratory distress eased and ability to breathe improved. Our medical staff monitored her situation until they began noticing a great improvement. Within a few days, Khaldiyah’s condition had stabilised and she was soon discharged from the ICU to rejoin her family at home.\nAccess to oxygen was a crucial, potentially life-saving element of Khaldiyah’s treatment. Having been internally displaced from Hama and struggling with various chronic illnesses, she was considered a high-risk patient.\n“Prior to coming to the hospital nobody knew how to help me or what was wrong with me, and once it became known that I had contracted COVID-19, the medical staff played a huge role in saving my life.”\nAs is often the case, underserved communities are frequently left behind when it comes to procuring crucial supplies and services needed to fight COVID-19. This is further evidenced by Khadliyah’s story, which is shared by multitudes of other Syrians. The ability of staff in such dire conditions to save lives when given the tools they need to succeed highlights the importance of tirelessly striving to ensure that health facilities on the ground receive the resources they need in order to continue saving their patient’s lives.", "pred_label": "__label__POS", "pred_score_pos": 0.8252866864204407} +{"content": "While energy security remains an essential mission, the IEA has evolved over the years and adapted to the transformation of the global energy system. Today, the IEA is at the heart of the global energy dialogue, providing relevant statistics and analysis, examining the full range of energy issues, and advocating strategies that will improve the reliability, affordability and sustainability of energy in its 30 Member States and beyond. The success of the Agency`s „open door” policy has enabled the IEA to deepen its cooperation with eight new countries through the association programme: Brazil, China, India, Indonesia, Morocco, Thailand, Singapore and South Africa. The IEA family now accounts for about 75% of the world`s energy consumption, up from 40% in 2015. In 2015, the IEA Ministerial Meeting approved a new modernization strategy, presented by the Agency`s new Executive Director, Fatih Birol, to strengthen the Agency`s role as a key to global energy policy. Ministers are focusing on creating a more inclusive and truly global agency through closer cooperation with emerging economies. The IEA was established as the leading international forum for energy cooperation on a wide range of issues such as security of supply, long-term policy, information transparency, energy efficiency, sustainability, research and development, technological cooperation and international energy relations. The International Energy Agency was established in 1974 to ensure the security of the oil supply. While energy security remains a central issue, the IEA is now at the heart of the global energy debate and focuses on a wide range of issues ranging from electricity security to investment, climate change and air pollution, energy access and energy efficiency. This first oil shock led to the creation of the IEA in November 1974, with a broad mandate for energy security and energy cooperation. This included a collective action mechanism to respond effectively to potential disruptions in oil supplies. The framework was enshrined in the IEA treaty „Agreement on an International Energy Programme,” whose newly created autonomous agency was hosted by the OECD in Paris.\nThe modernization of the IEA has been based on three pillars: strengthening and expanding the IEA`s commitment to energy security beyond oil, natural gas and electricity; Strengthen the IEA`s commitment to major emerging economies; and to put more emphasis on clean energy technologies, including energy efficiency. IEA agreement signed on 18 November 1974. From left to right: Ulf Lantzke, Special Adviser for Energy to the OECD Secretary General; Etienne Davignon, Belgian Ministry of Foreign Affairs, Chairman of the IEA-OECD Board of Directors; Emile Van Len The IEA was born with the oil crisis of 1973-1974, when developed countries found that they were not sufficiently equipped to cope with the oil embargo imposed by the major producers, which pushed prices to historically high levels.", "pred_label": "__label__POS", "pred_score_pos": 0.9752472639083862} +{"content": "Sustaining economic progress in a region fighting to end poverty\nThe Appalachia cultural region, which is part of the larger Appalachian Mountain range, stretches from southern New York to Northern Alabama. It is rich in natural resources and geographically close to major economic engines on the Eastern Seaboard. While the region has historically suffered from unemployment and below-average incomes, the past two decades have produced steady economic growth that has halved the area’s poverty rate.\nfootnote1 While this progress is meaningful, the recent global events caused by the health crisis have threatened to impede critical social and economic gains. In the above video, Appalachian Community Capital (ACC) President and Chief Executive Officer Donna Gambrell discusses the role Community Development Financial Institutions (CDFIs) play in fostering Appalachia’s economic growth, particularly as they try to minimize the impact of the coronavirus on the region’s small businesses.\nCDFIs provide underserved communities, often minority or impoverished, access to capital that encourages small business ownership. They’ve been crucial to supporting the Appalachia region’s economic progress. ACC, working in partnership with CDFIs across region, has financed nearly 70 small business loans and helped create or retain over 1,800 jobs—more than half of them going to low-income workers—since its founding.\n“I’m optimistic about the future of this region and the resilience of our economy,” Gambrell says. “There’s a growing recognition that we must do things differently—we’ve got to keep working to debunk the notion that this region doesn’t hold great opportunity.”\nBank of America operates a $1.6 billion CDFI portfolio with 255 partner CDFIs to provide access to capital to individuals and small businesses who do not qualify through traditional lenders. Recognizing the increased need for support during the health crisis, Bank of America committed $250 million in additional capital to CDFIs to facilitate lending through the Paycheck Protection Program, which it exceeded. The bank also provided $10 million in operating philanthropic grants, including a $100,000 grant to ACC, in addition to $3 million in loans to support the region’s small businesses to date.\nAs communities in Appalachia, and across the country, respond to the impact of the health crisis learn more about how Bank of America is helping CDFIs play a critical role in creating economic opportunity.\nOriginally published on 04/08/2021.", "pred_label": "__label__POS", "pred_score_pos": 0.8086140155792236} +{"content": "If facing end-stage organ failure, a kidney, pancreas, liver, lung, intestine or heart transplant will help you embrace life again.\nFeatured Services\nIf you have a condition that causes your liver to no longer work properly, you may need a transplant which replaces your diseased liver with a healthy, donated liver from another person.\nThese diseases occur when your body's immune system attacks the cells of your liver and biliary system.", "pred_label": "__label__POS", "pred_score_pos": 0.9928757548332214} +{"content": "Dr. Vukica Jovanovic is a Batten Endowed Fellow and an Associate Professor of Engineering Technology in Mechanical Engineering Technology Program. She holds a Ph.D. from Purdue University in Mechanical Engineering Technology, focuses on Digital Manufacturing, Magistar (Ph.D. candidate) degree in Industrial Engineering and Management, focused on Production Systems Design, and dipl.ing. degree in Industrial Engineering focused on Mechatronics, Robotics and Automation. She went through engineering pathways herself, completing master electrician degree when completing Technical School in Uzice, Serbia, focusing on pre-engineering program on high power voltage systems and maintenance of electro-mechanical systems. Her research is focuses on engineering pathways, career and technical education, digital thread, cyber physical systems, mechatronics, digital manufacturing, broadening participation, and engineering education. She is a Director of Mechatronics and Digital Manufacturing Lab at ODU and a lead of Area of Specialization Mechatronics Systems Design. She worked as a Visiting Researcher at Commonwealth Center for Advanced Manufacturing in Disputanta, VA on projects focusing on digital thread and cyber security of manufacturing systems. She has funded research in broadening participation efforts of underrepresented students in STEM funded by U.S. Department of Education, focusing on computer science and cybersecurity pathways, and from Office of Naval Research, focusing on mechatronic pathways. She is part of the ONR projects related to the additive manufacturing training of active military. She is also part of the research team that has multiple projects funded from NSF focusing on veteran pathways and their success in engineering. She leads the team that delivers the summer program to nine graders that focus on broadening participation of underrepresented students into STEM (ODU BLAST), funded by the Virginia Space Grant Consortium.\nDr. Anthony W. Dean has had several roles in academia. He is currently Assistant Dean for Research, Batten College of Engineering and Technology (BCET) at ODU. His previous appointments include Associate Professor of Engineering Technology and as Associate Director of the Institute for Ship Repair, Maintenance, and Operations at Old Dominion University (ODU).His research has focused mostly on control systems (integration and testing) and the reliability and maintainability of complex systems. He has been selected as both a NASA and an ONR Faculty Fellow. He regularly teaches courses in Marine Engineering and in Maintained Systems. Most recently Dr. Dean was on the Headquarters Staff the American Society of Naval Engineers. He received his Ph.D. from the Department of Engineering Management and Systems Engineering, and a B.S. in Nuclear Engineering Technology, from the Batten College of Engineering and Technology at Old Dominion University. Additionally, Dr. Dean received an MBA from the College of William and Mary. Prior to is academic career Dr. Dean was Director of Operations and Business Development for Clark-Smith Associates, P.C., and served as an Electrician in the US Navy aboard the USS South Carolina and the USS Enterprise.\nDr. Bullington is an experienced and accomplished leader in higher education and university administration with strong expertise in program management, organizational development, and student and academic affairs administration, with over two decades of university experience.\nDr. Bullington's research interests include student success - especially in the veteran and non-traditional student realm, higher education policy, and student access to higher education resources.\nProgram Director, Training Specialist; Director, ODU BLAST (Building Leaders to Advance Science and Technology); Professor in STEM Education and Professional Studies, Darden College of Education, Old Dominion University, VA.\nDr. Landaeta is an Associate Professor with tenure in the department of Engineering Management and Systems Engineering at Old Dominion University in Norfolk, Virginia. He holds a Ph.D. in Industrial Engineering and a M.S. in Engineering Management from the University of Central Florida, as well as, a B.S. in Mechanical Engineering from UNITEC Venezuela. He serves as an Associate Editor for the Engineering Management Journal and is the Old Dominion University Faculty Advisor of the Student Chapter of the Society of Hispanic Professional Engineers and the Student Chapter of the Engineering Management Honor Society.His scholarship focuses on generating, transferring, and applying multi-disciplinary knowledge that addresses current and future challenges in knowledge-intensive organizations. He has provided management coaching, training, and consulting to Fortune 100 companies and large government organizations. The American Society for Engineering Management recognized him with two Meritorious Service Awards in 2006 and 2012 and was elected Fellow of the society in 2014. Old Dominion University recognized him with the Shining Star Award in 2010, the Batten College of Engineering and Technology Excellence in Teaching Award in 2008 and the Industry Engagement Award in 2014. He was selected an entrepreneurship \"Entsminger fellow\" by Old Dominion University in 2015.\nAre you a researcher? Would you like to cite this paper? Visit the ASEE document repository at peer.asee.org for more tools and easy citations.", "pred_label": "__label__POS", "pred_score_pos": 0.5084972381591797} +{"content": "Pfizer and AstraZeneca vaccines proved highly effective against the Indian variant of Covid after two doses of the product. This was revealed by a study by the British health authorities, reports the BBC, specifying that with the second dose the two vaccines ensured a level of protection against the symptoms of the disease of the Indian variant equal to that recorded for the English variant. However, the two vaccines proved to be only 33% effective against the Indian strain three weeks after the first injection, compared to 50% effective against the English one. The Pfizer vaccine was found to be 88% effective in stopping the symptomatic disease of the Indian variant two weeks after the second dose, compared to 93% guaranteed compared to the variant that emerged in Kent. Astrazeneca revealed an efficacy of 60% against the Indian variant, 66% against the British one, therefore lower percentages but which may derive from the fact – according to the authors of the study – that the inoculations of the second dose of Astrazeneca started later than to those of Pfizer, which had received approval earlier.", "pred_label": "__label__POS", "pred_score_pos": 0.8982830047607422} +{"content": "Press Kit\nResources for members of the media & bloggers.\nShot@Life is monitoring the evolving landscape of the Taliban’s takeover in Afghanistan. We’re deeply concerned by the imminent threats to essential health services and are collaborating closely with our UN partners to safeguard the health and human rights of both vulnerable Afghan children and frontline health workers — many of whom are women.\nAfghanistan is one of the last frontiers for polio eradication, a landmark feat that when achieved, would make it only the second disease to be eradicated worldwide. While the polio program has sustained operations for decades amidst insecurity and conflict, Shot@Life is renewing our advocacy to ensure that all populations are shielded from disease outbreaks and have continued access to lifesaving immunizations and quality healthcare.", "pred_label": "__label__POS", "pred_score_pos": 0.5428046584129333} +{"content": "According to Gartner, 80% of an application’s code is provided by dependencies. However, the vulnerabilities of these dependencies are rarely monitored.\nOWASP’s Dependency Check tool (https://www.owasp.org/index.php/OWASP_Dependency_Check) can automatically list and check whether an application dependency has a vulnerability.\nTo do this, this tool uses the NIST National Vulnerability Database (NVD) website. This database publishes vulnerabilities in the form of CVEs (Common…", "pred_label": "__label__POS", "pred_score_pos": 0.9998234510421753} +{"content": "Prior research suggests that predicting defect-inducing changes, i.e., Just-In-Time (JIT) defect prediction is a more practical alternative to traditional defect prediction techniques, providing immediate feedback while design decisions are still fresh in the minds of developers. Unfortunately, similar to traditional defect prediction models, JIT models require a large amount of training data, which is not available when projects are in initial development phases. To address this flaw in traditional defect prediction, prior work has proposed cross-project models, i.e., models learned from older projects with sufficient history. However, cross-project models have not yet been explored in the context of JIT prediction. Therefore, in this study, we empirically evaluate the performance of JIT cross-project models. Through a case study on 11 open source projects, we find that in a JIT cross-project context: (1) high performance within-project models rarely perform well; (2) models trained on projects that have similar correlations between predictor and dependent variables often perform well; and (3) ensemble learning techniques that leverage historical data from several other projects (e.g., voting experts) often perform well. Our findings empirically confirm that JIT cross-project models learned using other projects are a viable solution for projects with little historical data. However, JIT cross-project models perform best when the data used to learn them is carefully selected.", "pred_label": "__label__POS", "pred_score_pos": 0.9895655512809753} +{"content": "Description\nA once a day everyday supplement to support optimal wellbeing. It contains nutrients such as the B vitamins and vitamin C that contribute to the reduction of tiredness and fatigue and help increase the body?s resistance to stress. It also provides nutrients to support immune function and protect body cells against oxidative stress to minimise the environmental impact on delicate body tissues such as the skin.\nThis is a high potency ?all-in-one? formula designed to augment dietary intake, particularly useful in times of stress, or for those at risk of nutritional deficiencies such as the elderly, those with special dietary requirements such as vegetarians or for anyone following a weight management diet where calorie intake is restricted.", "pred_label": "__label__POS", "pred_score_pos": 0.9683421850204468} +{"content": "MOG 03:10pm Deep-ultraviolet Laser Ablation Sampling for Mass Spectrometry Remilekun O. Lawal; Fabrizio Donnarumma; Kermit K. Murray\nHigh resolution sampling of biological systems is crucial to revealing the differences in proteins and metabolites amongst heterogeneous cells. Laser ablation sampling for mass spectrometry is a powerful method for analyzing biomolecules in tissue under ambient conditions with high spatial control while eliminating the need for external matrices. It allows off-line analysis by liquid chromatography tandem mass spectrometry and can be combined with mass spectrometry imaging for region of interest selection. The most efficient lasers currently used for ablation sampling use mid-infrared wavelengths that are diffraction limited to spot sizes tens of micrometers in diameter. Short wavelength lasers can be focused to order of magnitude smaller spot sizes for efficient ablation with minimal thermal damage to adjacent sample areas.", "pred_label": "__label__POS", "pred_score_pos": 0.5056029558181763} +{"content": "The Taylor M. Brown Memorial Award was established in honor of biosciences graduate student Taylor M. Brown. Taylor was a long-standing and vibrant member of the UCLA community. As a UCLA undergraduate, she majored in Microbiology, Immunology and Molecular Genetics, receiving her B.S. in 2015. She then joined the Immunity, Microbes, and Molecular Pathogenesis Home Area in the Molecular Biology Interdepartmental Program for her Ph.D., where she pursued her interest in understanding host-pathogen interactions. Taylor was deeply committed to increasing diversity in the biosciences, serving as an active member of the Association for Multi-Ethnic Bioscientists’ Advancement (AMEBA) and the UCLA SACNAS Chapter (SACNAS@UCLA). She was passionate about teaching, mentoring, and outreach. Her kindness and compassion made a lasting and widespread impact on the UCLA biosciences community. Taylor’s many accomplishments, her promise as a scientist, and her strong dedication to diversifying the biosciences were recognized by her selection in 2018 as a Howard Hughes Medical Institute Gilliam Fellow.\nThe Taylor M. Brown Award recognizes exceptional Ph.D. students in the biosciences who reflect the characteristics that made Taylor such a special member of the UCLA community. The awardees are well-rounded, with strong interpersonal skills and broad interests, and are passionate about mentorship, leadership, teaching, and science. They are highly engaged with the UCLA biosciences community and have a powerful commitment to increasing diversity in the biosciences.\nKimberly Martin, 2021 Awardee Kimberly Martin is a Ph.D. candidate in Social Psychology in the labs of Drs. Annette Stanton and Kerri Johnson. Kimberly’s dissertation research is focused on understanding the experiences of Black Americans in healthcare. She is actively involved in the UCLA Underrepresented Graduate Students in Psychology (UGSP) organization, and established UGSP’s Transfer Outreach Committee. She also serves on the Brain Research Institute’s Equity, Diversity & Inclusion Advisory Board. Kimberly is an instructor for the VIP Scholars Program, where she teaches social psychology courses to underrepresented high school students. She has also participated as a panelist and speaker in numerous outreach activities for high school and undergraduate students. Kimberly is currently a Cota Robles Fellow and was an NIMH T32 Predoctoral Fellow and a 2020 UCLA Political Psychology Fellow.\nTina Del Carpio, 2021 Awardee Tina Del Carpio is a Ph.D. candidate in Ecology and Evolutionary Biology in the lab of Dr. Kirk Lohmueller. Tina’s thesis research is focused on investigating recombination rates in dogs and wolves, and also on investigating the impact of the Competitive Edge program on graduate education. Tina is a passionate advocate for mental health and the founding member of the UCLA EEB Mental Health Working Group. They have contributed to training sessions for the EEB Department on supporting trans and non-binary students, were a member of the EEB Antiracism Task Force, and have participated in numerous career and mental health panels for undergraduate and graduate students. Tina is an NSF Graduate Research Fellow, a former NHGRI T32 Predoctoral Fellow, and a recipient of a 2021 UCLA EEB Special Faculty Award for Departmental Service.\nFunds for the discretionary award are provided by UCLA Graduate Programs in Bioscience. Funds for the travel award are provided by the Howard Hughes Medical Institute Gilliam Fellows Program.", "pred_label": "__label__POS", "pred_score_pos": 0.7235941290855408} +{"content": "Abstract\nPurpose of Review: Children with unilateral deafness may experience challenges with language development, educational progress, and social interaction. Rehabilitation with a cochlear implant (CI) may minimize these impacts. This review examines the characteristics of children with unilateral deafness presenting for candidacy assessment. Recent Findings: Forty-nine children with unilateral deafness were assessed. Many (15/49) did not meet candidacy criteria due to cochlear nerve aplasia/hypoplasia (12/49), while 17/49 elected not to pursue CI. The most common etiologies in those 17/49 (35%) who met candidacy and consented to CI were congenital cytomegalovirus (cCMV) (41%) and trauma (26%). Summary: Many children with unilateral deafness who present for assessment do not go on to receive an implant due to anatomic contraindications or their desire for non-intervention. This review highlights the high prevalence of cCMV amongst children with unilateral deafness presenting for CI where the potential for progression to bilateral hearing loss may influence decision for implantation.\nBibliographical notePublisher Copyright:\n© 2017, Springer Science+Business Media, LLC.\nKeywords Children Cochlear implantation Cochlear nerve aplasia Cochlear nerve hypoplasia Cytomegalovirus Hearing loss Pediatric Unilateral deafness", "pred_label": "__label__POS", "pred_score_pos": 0.993497371673584} +{"content": "Abstract\nNews reports (e.g., Abrams, 2008) and scholarly research (e.g., Wiersma & Fifer, 2005) have indicated increasing concern that parent-spectator behavior at youth sport events may be problematic. Multiple strategies have been used to influence spectator behavior in youth sport contexts (e.g., “Silent Sundays”). However, it is unlikely that interventions aimed at changing parent-spectator behaviors have adequately considered young athletes’ perspectives, because little is known about how children want parents to behave during youth sport events. Therefore, children (ages 7–14 years) were asked to describe how parents actually behaved at youth sport events and how they wanted parents to behave. Through grounded theory analysis (Charmaz, 2000), three parent “roles” emerged from the data—supportive parent, demanding coach, and crazed fan.\nKeywords Child preferences Fans Spectators", "pred_label": "__label__POS", "pred_score_pos": 0.5305989384651184} +{"content": "272-9 Long-Term Productivity in Traditional, Organic and Low-Input Management Systems of the Upper Midwest.\nTuesday, October 24, 2017: 4:05 PM\nTampa Convention Center, Room 7\nAbstract:\nTraditional cropping practices in the Upper Midwest are marked by low-diversity and high tillage disturbance. Eight years of production were evaluated to determine potential benefits of adopting low-input and organic management practices on system productivity. Increased crop rotation diversity, reduced tillage, and use of animal manure or no fertilizer, employed in organic and low-input systems, were compared to traditional management. A four-year, corn/soybean/wheat-alfalfa/alfalfa rotation replaced the traditional two-year corn-soybean rotation. Strip-tillage replaced conventional moldboard plow. Animal manure or no fertilizer, respectively in organic and low-input systems, replaced inorganic fertilizers. Eight years of findings indicated overall system productivity was better under traditional management, largely due to tillage impacts on corn yields. Within organic and low-input systems, tillage also had an impact on productivity due to a positive influence on corn yields. These systems were marked by strict adherence to a tillage management scheme. Future research should investigate rotational tillage schemes and alternative mechanisms to improve nutrient availability in organic and low-input production systems.\n<< Previous Abstract |\nNext Abstract", "pred_label": "__label__POS", "pred_score_pos": 0.8765283823013306} +{"content": "2020/10/26\nWhat is \"Occupational Therapy\"?\nOccupational Therapy is provided by MHF among other services.\n‘Occupation’ means the practical and purposeful daily activities a person performs that are meaningful and important to them. This can include necessary tasks and routines such as looking after you/ personal care, engaging in enjoyable leisure or recreational activities and achieving productive goals within employment and education.\nAn occupational therapist focuses on you as an individual, assessing your strengths and needs. They will work with you at an appropriate pace to understand how your health difficulties impact on your ability to fulfill activities and roles that are important to you.\nOccupational therapists’ can help you to:\n- Develop or maintain your skills and independence in activities of daily living.\n- Establish a satisfying balanced routine to enable you to get the most from life.\n- Identify and participate in meaningful activities\n- They can support you to set and achieve realistic goals.\n- Develop coping strategies and maintain interpersonal relationships.\n- Restoring independence and emotional well-being.\nMHF occupational therapist is Danette Mc Rae Gumbs\nMore Articles →", "pred_label": "__label__POS", "pred_score_pos": 0.8826361894607544} +{"content": "Technology and Instructional Materials Allotment\nThe Technology and Instructional Materials Allotment (TIMA) can be used to purchase instructional materials; technological equipment; certain related software, systems, and services; and salaries for specific technical support employees, as described in Texas Education Code (TEC), Chapter 31 Instructional Materials and Texas Administrative Code §66.1307.\nEach district and open-enrollment charter school is entitled to an instructional materials allotment amount determined biennially by the commissioner and based on the legislative appropriation. These funds become available after September 1 of each odd-numbered year. The allotment is accessed through EMAT (must obtain EMAT access and complete the training and prerequisites first).\nTIMA Access for the 2021–22 School Year\nThe new allotment has been loaded into EMAT. If carry-over funds are not available, districts and charters may use up to 80% of it prior to September 1, 2021. The new funds can be used for pre-approved disbursement requests and materials for which publishers have agreed to the delayed payment option (Texas Education Code, §31.0215). The list of publishers accepting delayed payment is found in EMAT under Reports.\nPre-approved requests will be paid after September 1, as revenue becomes available and after the delayed-payment publishers have been paid.\nYou will notice that the 2022–2023 allotment is lower than it has been in previous years. The legislature reduced the allotment to more closely match the projected costs of\nProclamation 2021 and Proclamation 2022 instructional materials for prekindergarten systems, health, and physical education; however, they did indicate their intention to increase future allotments to more closely align with previous allocations. Examples of Allowable Expenses\nBefore submitting a disbursement request, review examples of allowable and non-allowable expenditures to understand what can be covered with these funds.\nTo determine the eligibility of a product or service (before or after entering a disbursement request in EMAT), complete the online Allotment Disbursement Requests form. TEA will contact you if more information is needed to determine the eligibility.\nIn addition to Currently Adopted Instructional Materials adopted by the State Board of Education under TEC, §31.024, TIMA funds also can be used to purchase:\nNon-adopted instructional materials (e.g., Fountas/Word Study, RAZ Kids, Sirius Education) Consumable instructional materials, including workbooks, student kits, and magazines Versions of non-adopted instructional materials that are fully accessible to students with disabilities, including large-print, braille, and audio materials Bilingual materials as provided by TEC, §31.029, including Spanish-to-English dictionaries and flash cards Instructional materials for use in college preparatory courses, including dual-credit textbooks and dual-credit online courses, as provided by TECs, §28.014 and §31.031 Supplemental instructional materials, as provided by the TEC, §31.035, including band instruments and NWEA Maps State-developed, open-source instructional materials, as provided by TEC, Chapter 31, Subchapter B-1, including Texas Home Learning courses and open education resources\nTIMA funds can be used for services that assist the technology or instructional materials used in the classroom, including:\nActivities related to the local review and adoption of instructional materials, such as a contracted service to determine instructional materials Texas Essential Knowledge and Skills (TEKS) coverage Training educational personnel directly involved in student learning in the appropriate use of instructional materials, including IMCAT registration or instructional materials trainings offered by publishers/vendors, and training for online testing. Providing access to technological equipment for instructional use, including wi-fi, postage during COVID, Google Suite, Screencastify, Zoom, single sign-on services, and internet connectivity Inventory software or systems for storing, managing, and accessing instructional materials (e.g., Canvas, Hayes Software Learning Management Systems, internet filtering) Software or the portion of a system that analyzes the use and effectiveness of instructional materials The salary and other expenses of an employee who provides technical support for the use of technological equipment directly involved in student learning (e.g., instructional technology trainer, computer/laptop technician) Printing services, printer paper, and ink/toner for copies of instructional materials (e.g., digital licenses that permit printing, black line masters) for teachers and students\nTIMA funds can be used for technological equipment that contributes to student learning or supports the use of instructional materials, including:\nLaptops Headphones Desktops Calculators Charging carts Protective cases for tablets\nExamples of allowable salary disbursement requests include:\nAn employee who provides technical support for a learning management system (LMS) used to access instructional materials An employee who provides support through planning and professional development for teachers and staff to integrate technology into classroom instruction A computer lab technician who directly assists students An employee who performs maintenance and provides technical support for technological equipment used in labs and classrooms\nTo use the allotment for the salary or appropriate portion of the salary of an employee, districts must request a disbursement through EMAT and indicate the pay period on each submission. Salary disbursements are provided as reimbursements to the district’s payroll account.\nSalary requests are accepted three times per year, and the deadlines remain the same every year:\nNovember 30 for September, October, November February 28 for December, January, February May 31 or end-of-contract date for the remaining months\nTIMA funds cannot be used for the following materials and services:\nGeneral professional development Programs for non-instructional purposes, such as scheduling Online gradebooks Book covers Physical conduits that transmit data, such as cabling and wiring or electricity Equipment used for moving or storing instructional materials (e.g., forklifts, pallets, pallet jacks, shrink wrap) Office and school supplies (e.g., pens, paper clips, desks, batteries, etc.) Items not directly related to student instruction, such as furniture, athletic equipment, extension cords, temporary contractors, or video surveillance equipment (e.g., chairs, basketballs, bleachers, surge protectors) Services for installation of equipment or hardwiring Travel expenses, including lodging, mileage, flights, or meals Salaries for teachers, testing coordinators, or instructional materials coordinators Instructional Materials and Implementation Division 1701 North Congress Avenue, Room 3-110 Austin, Texas 78701-1494", "pred_label": "__label__POS", "pred_score_pos": 0.889551043510437} +{"content": "A 62-year-old woman presented to the hospital with lower extremity pain. The pain had initially begun in her left leg distal to her knee. She had thought the pain was secondary to osteoarthritis.\nA recent study assessed the risk of intracranial hemorrhage in patients taking direct oral anticoagulants who experience minor head injury. Would you recommend computed tomography head imaging for this patient population?\nA 23-year-old military pilot presented to an aviation clinic for his annual flight physical examination. At the start of the examination, the patient drew the flight surgeon’s attention to a lump on the left side of his neck.\nA 70-year-old man who had undergone pacemaker placement for atrial fibrillation 21 years ago, with a generator change 4 years ago, was transferred from an outside hospital to our hospital for evaluation of fever of unknown origin.\nA 64-year-old Nigerian man with no pertinent medical history was admitted to the hospital for evaluation of the recurrence of a painful left axillary nodule.\nA 15-year-old boy presented to the emergency department with acute onset of right knee pain. While playing basketball, the patient had attempted a layup and had felt a “popping” sensation in midair. He was unable to ambulate after the injury.\nAn 83-year-old morbidly obese woman presented to the emergency department with progressively worsening atraumatic right hip pain for the past week that had made her unable to walk.\nA neonate was noted to have swelling of the right thigh on her initial newborn examination. The patient had been born via unplanned cesarean delivery for breech presentation.\nIn December 2018, a 27-year-old man who had recently emigrated to the United States from India had struck his right elbow into a door. Over the following weeks, he had had experienced progressive pain and swelling in the joint.\nA 60-year-old man presented to our emergency department after detecting persistently low SpO2 measurements on his home pulse oximeter device during the peak of the COVID-19 pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.7534772157669067} +{"content": "Industrial\nLandsdale North Industrial Park The efficient delivery of a significant 40 hectare industrial estate – developed, sold and settled in just over two years. Overview\nindustrial estate\nranging from 1,100m\n2 to 1.4ha Project Background The Landsdale North project was highly successful with 116 lots developed and sold in just over two years.\nA well-located industrial estate on the corner of Madeley Street and Furniss Road in Landsdale, the site was acquired in 2007 in the early years of the global financial crisis.\nA rapid development programme and strategic off-market marketing campaign saw Hesperia deliver outstanding outcomes to investors, even under the challenging investment and operating environment of the GFC.\nProject Details Stages were rapidly developed in parallel, ensuring efficient delivery and strong market interest.\nA wide range of lot sizes were developed to cater to a number of national and local owners and tenants.\nIn later stages of the development process, concerns emerged regarding the potential for migration of landfill gas discovered on an adjacent inorganic waste site. Intelligent response was needed to minimise project delivery impacts. To counter potential issues, the team completed complex investigations and detailed audits in less than six months, ensuring development could continue without delay.", "pred_label": "__label__POS", "pred_score_pos": 0.7840067148208618} +{"content": "The electrical vehicles revolution is definitely here and there is abundant excitement in the air. As the EV charging infrastructure in India gets built-in record scale ground up, there is a dire need among EV owners, for a single go-to place for verified listings, considering how charging is crucial when it comes to EVs.\nDelhi-based EV Plugs was co-founded in 2021 by EV enthusiasts Manish Narang, Kapil Narang and Ashwani Arora. Its app went live on Wednesday with 1000+ verified listings alongside tips for the EV owners on making the most of it while being there. The free app is available on both iOS and android and the web-based one is available at www.evplugs.co.in\n“We expect the market to be flooded with EVs across categories. However, it will take several decades before the market reaches a level similar to diesel and petrol where one can be assured of finding one charging station within a few kms,\" Manish Narang, co-founder, EV Plugs, said.\n\"The aim is to emerge as the one-stop platform for multiple needs related to EVs for the millions of owners who would be owning one sooner or later.\nEV Plugs has emerged as India's largest EV Charging Infrastructure aggregator with over 1000+ verified listings, helping to remove the range anxiety issues many existing and potential EV owners have.", "pred_label": "__label__POS", "pred_score_pos": 0.8368993997573853} +{"content": "The probiotic bacterial strain Lactobacillus plantarum ZS2058 has been proven to alleviate colitis due to its ability to synthesize conjugated fatty acids (CFAs). To investigate the specific functions of CFAs produced by this probiotic bacterium, a-linolenic acid was isomerized by Lactobacillus plantarum ZS2058, and two different conjugated a-linolenic acid (CLNA) isomers were successfully isolated: c9, t11, c15-CLNA (CLNA1) and c9, t11, t15-CLNA (CLNA2). The effects and mechanism of CLNA crude extract and individual isomers on colitis were explored. CLNA significantly inhibited weight loss, the disease activity index, colon shortening. Additionally, CLNA improved histological damage, protected colonic mucous layer integrity and significantly upregulated the concentration of tight junction proteins (ZO-1, occludin, and claudin-3). CLNA significantly attenuated the expression of proinflammatory cytokines (TNF-a, IL-1▀, and IL-6) while upregulating the expression of the colonic anti-inflammatory cytokine IL-10 and nuclear receptor PPAR┐. Moreover, the activity of oxidative stress-related enzymes (superoxide dismutase, glutathione peroxidase and catalase) was increased by CLNA. The myeloperoxidase activity was significantly decreased by CLNA. Meanwhile, the concentrations of CLNA in the liver and colonic conjugated linoleic acid (CLA) were significantly increased in response to CLNA supplementation. Furthermore, CLNA could rebalance the gut microbial composition damaged by DSS, including increasing the a-diversity. CLNA1 and CLNA2 increased the abundance of Ruminococcus and Prevotella, respectively.", "pred_label": "__label__POS", "pred_score_pos": 0.987175703048706} +{"content": "Background: Effective treatments for irritable bowel syndrome with constipation (IBS-C) are lacking. Aim: To assess the efficacy and safety of lubiprostone in IBS-C. Methods: A combined analysis was performed among 1171 patients with a Rome II diagnosis of IBS-C in two phase-3 randomized trials of lubiprostone 8 mcg vs. placebo twice daily for 12 weeks. Using a balanced seven-point Likert scale ranging from significantly relieved (+3), to significantly worse (-3), patients responded on their electronic diary to the question: 'How would you rate your relief of IBS symptoms over the past week compared to how you felt before you entered the study?'. The primary efficacy endpoint was the percentage of overall responders. Results: Using an intent-to-treat analysis with last observation carried forward, a significantly higher percentage of lubiprostone-treated patients were considered overall responders compared with those treated with placebo (17.9% vs. 10.1%, P=0.001). Patients treated with lubiprostone reported a similar incidence of adverse events to those treated with placebo. Conclusions: The percentage of overall responders based on patient-rated assessments of IBS-C symptoms was significantly improved in patients treated with lubiprostone 8 mcg twice daily compared to those treated with placebo. Lubiprostone was well tolerated with a favourable safety profile.", "pred_label": "__label__POS", "pred_score_pos": 0.9662166237831116} +{"content": "Parents may worry more about their kids driving while impaired by alcohol or texting, but they should be equally concerned about drowsy driving. [...]\nIt seems that many prescription drug users do not understand (or care about) the dangerous side effects of these medications. Nor are they aware how their use can impair driving. This, in spite of directly spoken warnings from healthcare professionals and multiple warnings found on drug labels and recited by dispensing pharmacists. [...]", "pred_label": "__label__POS", "pred_score_pos": 0.6193304061889648} +{"content": "The gift of intimate strangersSep 27, 2021 02:47PM ● By Elayne Clift\nI was 22 years old when I first flew across the Atlantic for a solo adventure in Europe. I was meant to take the trip with my best friend, but she became engaged and I wasn’t going to wait for anyone else to accompany me on this dream trip.\nI’d been seduced by travel as a child on summer holidays to Canada, home of my paternal grandparents. Bitten by the travel bug, nothing compared to the idea of seeing some of Europe’s most amazing countries and capitals.\nArmed with a Eurail pass and modest hotel reservations, I flew from New York to Amsterdam. From Amsterdam’s canals to London’s museums, pubs and palace, I traveled on to the Champs-Élysées and cafes of Paris, the Colosseum of Rome, and the magnificent statue of David in Florence.\nThey were magical places that spurred me on to more worldwide travel in the years to come. But the really special part of that initial journey resided in the people I met and the conversations we shared in trains, restaurants, hotels and elsewhere. No sooner did I bid farewell to one new friend than I made another. Some were young travelers like me, others were wise elders—and in two cases, attractive men whom I would see again.\nEveryone I interacted with told stories that moved me, made me laugh, tear up, and most importantly, share the truths of my own life. I felt for the first time like I’d climbed into my own skin. No need for game playing, diminishing or apologizing for my thoughts, so often called for from American females in the ’60s. I could be who I was, and be appreciated for it. It was an entirely new, sensual experience, devoid of sexual overtones. And it changed my life forever.\nYears later on a visit to England, I stayed in a bed and breakfast run by a woman whose husband had suffered a workplace injury and was unable to work. Every day, she repeated her routine—cooking breakfast for guests, changing beds, cleaning rooms and caring for her husband and children. Every day, we shared an intimate, unspoken moment when, smiling at each other, she knew that she would never have my life of freedom and mobility, and I understood that I would never be subjected to her burdens. It made me sad, but helped me understand my privileged place in the world.\nThen there was the woman I literally bumped into in a New York shop. She was accompanied by two children and a dreadful husband who barked at her as she enjoyed a brief shopping moment. I don’t know why, but as I left the shop, I whispered to her, “You have the courage to do what you need to.” Later, crossing the street, I bumped into her again. I quickly hugged her and she hugged me back. I often wonder if, in that moment, a decision was made that led to her liberation.\nAnd how can I forget Roy Cesarini, whom I met in a café by the sea in Santa Margherita Ligure, Italy? Roy was a dapper older gentleman whose sparkling blue eyes, pink cheeks, and broad smile beneath a carefully trimmed mustache drew me to him immediately. Roy had noticed that I was struggling with the menu and asked quietly, “May I be of some assistance?”\nAnd he began to tell his story. He had been a British prisoner of war due to Mussolini’s collaboration with Germany in World War II. Sent to a work farm in the UK, he quickly endeared himself to everyone, including the farmer’s daughter, Elizabeth. The two fell in love.\nBut one day, Elizabeth was warned that she could be arrested for collaborating with the enemy. Shortly thereafter, Roy was sent to another farm in Scotland. They wrote to each other, but their letters were never received and each thought the other had forgotten about the other.\nAfter the war, Roy returned to Italy, married and became a restaurant owner. But he never forgot Elizabeth. When his wife died, he learned that Elizabeth had also passed away. From then on, he visited England annually to lay flowers on her grave.\n“She was my first love and I don’t forget her,” he said.\nHis moving story taught me a lot about love.\nSome years later, I heard that Roy, too, had passed away. Like Elizabeth, I fell in love with him, and I don’t forget him.\nThese treasured memories, many born of travel, have been true gifts in my life. They offered me opportunities for deeper insight and heightened compassion, a genuine appreciation of people’s life stories, and a kind of intimacy that I would’ve hated to have missed.\nI’m a better human being for those moments shared with intimate strangers.", "pred_label": "__label__POS", "pred_score_pos": 0.8370020389556885} +{"content": "This week, Mighty Earth CEO Glenn Hurowitz sent a letter to European Commission President Ursula von der Leyen on the need to ensure environmental and human rights conditions for all EU bailouts and recovery support. The letter is reprinted below and available here.\nDear President von der Leyen,\nThank you for your environmental leadership and commitment to advancing the European Green Deal as the basis of the EU’s recovery strategy, and we applaud the proposed €40bn Just Transition Fund to assist member states to transition towards climate neutrality and a more circular economy.\nMighty Earth is a global environmental organization with a significant and growing interest in ending land-grabbing, human rights abuses, and environmental destruction linked to commodities imported into the EU. We focus heavily on areas of outsized importance to the climate that receive insufficient attention from policymakers and the private sector. We have driven adoption of zero-deforestation sourcing policies across the palm oil, cocoa and rubber industries, and helped launch a CSO-industry partnership, Responsible Steel, under which several of the world’s largest steel companies have committed to science-based targets.\nIn that context, I am writing to urge you to ensure all post Covid-19 EU bailout and recovery support for EU-based tire and rubber, auto, car rental, ride-share and aviation companies is aligned with the European Green Deal, supports environmental and human rights standards, and helps build a green, just and healthy economy.\nThe rubber industry\nThe tire and automotive industries are the largest market for natural rubber. Between 2003 and 2014, the rubber industry tore down 75,000 square kilometers of tropical forest, an area the size of Ireland. This deforestation was responsible for an estimated 3.75 gigatons of pollution during that time, comparable to the amount produced by Europe in a year. Land-grabbing is widespread in the sector, and we are finding companies are using the Covid-19 lockdown as a cover to seize and clear land while nobody appears to be watching. For example, in March, Vietnam-based HAGL destroyed forests on two sacred mountains earmarked for return to local Indigenous peoples in Ratanakiri in Cambodia. HAGL’s largest investor is THACO, which assembles cars in Vietnam for auto companies including Peugeot, Mazda and Kia. While low rubber prices in the last few years have reduced incentives for deforestation and land-grabbing, increased commodity prices in the absence of strong conservation policies would create new incentives for aggressive deforestation.\nPlanning a post-pandemic recovery to ensure a greener future\nHigh volumes of EU and EU-backed bailout support distributed over the coming months will shape the EU tire and rubber, auto, car rental, ride-share and aviation industries for years to come. Many EU-based companies in these sectors will benefit from this support. EU airlines are seeking €33bn in emergency bailout support, while tire companies like Continental, Michelin and Pirelli are seeking state aid, bailout or recovery assistance. Insisting on green conditions is possible: Air France-KLM was required to halve emissions, cut short-haul flights, and use more sustainable aviation fuel by 2024 to qualify for bailouts from the French and Dutch governments. However, few other bailouts to the transport sector have set conditions on carbon emissions or deforestation, let alone curbing the human rights abuses so rampant in the rubber industry.\nAction Points\nWe urge you to ensure that all EU-based companies that rely on rubber in their key products or connected to transport are aligned with the European Green Deal and legally bound by environmental and human rights conditions when accessing EU or EU-backed recovery support. In particular, we would ask you and your colleagues within the Commission to tie public EU and EU-backed recovery funds to the following conditions:\n1) Environment\nAll companies receiving bailout funds should be committed to the European Green Deal, the Paris Agreement, and to achieving net zero carbon neutrality by 2025. They should all have measurable action plans to transition towards a net zero carbon future. Airlines should set out plans for carbon neutrality by 2025 and for rapidly shifting to sustainable aviation fuels and mitigating the full climate impacts of the industry, including rubber deforestation. Auto, car rental and ride-share companies should set a target date by which they only provide electric vehicles made from low carbon materials – including zero carbon steel – and vehicle-scrappage should be in line with circular economy principles. All tire, rubber and auto companies seeking EU or EU-backed bailouts should have clear ‘Zero Deforestation’ and ‘Fire-free’ sourcing policies for natural rubber and time-bound plans to implement and enforce them. To quality for aid, these companies should have credible plans in place to achieve transparency and traceability throughout their raw materials supply chains, which will ultimately be necessary for them to align with the EU’s deforestation action plan.\n2) Human Rights\nBusinesses seeking EU bailout support should have robust policies and practices in place that recognize and ensure workers’ rights throughout their supply chains. This means a commitment to the ILO Core Conventions, which include human rights commitments on health and safety, freedom of association, gender equity and on forced, bonded, trafficked and child labor. All corporations should be committed to a living income and living wage. Tire and rubber corporations in particular should commit to recognize and respect the customary land tenure rights of Indigenous and local communities, as well as to ending all involvement in harassment, attacks, or killings of Indigenous peoples and local community members defending their land, forests and other natural resources.\nThis moment represents a significant opportunity to build a healthy, low and zero-carbon economy. I would be delighted to have an opportunity to discuss these proposals with you or your staff.\nWe use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept”, you consent to the use of ALL the cookies. However you may visit Cookie Settings to provide a controlled consent.\nThis website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.5554794073104858} +{"content": "Creator: Date: Abstract:\nThis study examines information-sharing practices within the Seasonal Agricultural Worker Program (SAWP). Drawing on Foucauldian theory and critical discourse analysis (CDA), I analyze 61 documents for their content, codification of stakeholder relationships, and use of discourse. Documents were selected based on creation, use, or circulation within Ontario, and \"official\" status - at least one stakeholder group would look to the document for (perceived) reliable information. I argue that documents function as material actors, alongside (sometimes beyond) human actors, making physical impact on SAWP bodies and realities. Documents communicate, discipline, and uphold neoliberal structures surrounding the program; through consistent sharing of narrow, \"work-related\" information, and the rare inclusion of more well-rounded, \"non-work\" knowledge, documents subtly discipline the boundaries of acceptable/unacceptable communication. In doing so, material actors perpetuate a program which does not consider the varied, complex needs of \"whole workers\" (McLaughlin et. al., 2017), but treats them as disposable labouring bodies.", "pred_label": "__label__POS", "pred_score_pos": 0.9705670475959778} +{"content": "Explorations of Genesis 2 intent on recovering God's ideal for the interrelationship between male and female often zoom in on the creation of Eve. We are better able to appreciate how the narrative supports that ideal when we engage the whole chapter.\nToo often the patriarchy of Bible culture has been confused with the moral teachings of Scripture. This workshop will explore how Christians working to end slavery challenged power, dominance, and self-interest in interpreting Scripture so that the church might become more effective agents of reconciliation in the world. What might egalitarians today learn from the interpretative methods of the abolitionists in their work as agents of gender justice?\nCultures of hierarchy maintain authority by claiming ontological distinction. The power and dominance inherent in hierarchy, which directly conflict with ontological equality, perpetuates abuse. This session will examine the abuse that results from hierarchical human relationships and the biblical response to dominance.", "pred_label": "__label__POS", "pred_score_pos": 0.9855799078941345} +{"content": "On September 17, 2021, the First District of the Illinois Appellate Court — which covers appeals from Cook County, Illinois — addressed a hotly contested issue under the Illinois Biometric Information Privacy Act (BIPA): which statutes of limitations apply to BIPA claims? In\nTims v. Black Horse Carriers, Inc. (2021 IL App (1st) 200563), the court concluded that a five-year limitations applies to some BIPA claims and a one-year limitations period applies to others.\nThere is no statute of limitations in BIPA which has led to litigation over which limitations period under Illinois law should apply to BIPA claims. In\nTims, the plaintiff, a former employee of defendant, filed a class action complaint alleging that defendant did not comply with certain BIPA provisions in connection with its so-called biometric time clocks. The defendant moved to dismiss, arguing these claims were untimely under Illinois’ one-year limitation period for “slander, libel or for publication of matter violating the right of privacy” under 735 ILCS 5/13-201. The trial court denied the motion, concluding instead that the Illinois “catch-all,” five-year limitation period under 735 ILCS 5/13-205 for “all civil actions not otherwise provided for” applied to the plaintiff’s BIPA claims.\nOn interlocutory appeal, the Illinois appellate court held that\nboth periods — one-year and five-years — apply, depending on the specific alleged BIPA violation.\nIn particular, the Court held that the five-year statute of limitations applies to BIPA claims alleging failure to develop a publicly available retention and destruction schedule (Section 15(a)); collecting biometrics without written notice and release (Section 15(b)); and failing to take reasonable care in storing, transmitting, and protecting biometric data (Section 15(e)).\nBy contrast, claims for improper disclosure (Section 15(d)) and improperly selling, leasing, trading or otherwise profiting from biometrics (Section 15(e)) are subject to a one-year statute of limitations because such claims, according to\nTims, involve “publication” of biometrics that implicate Illinois’ one-year statute of limitations.\nThe\nTims decision thereby endorses two potential sets of limitations periods, even within the same complaint. Certain of the most common BIPA claims — failure to maintain and comply with a publicly available retention policy under Section 15(a), and failure to provide written notice and receive written consent under Section 15(b) — are afforded a lengthier limitations period of five years, whereas improper disclosure claims under Section 15(d) must be brought within one-year. Further, Tims suggests that “multiple recoveries of liquidated damages” could be recovered for each BIPA subsection violated (2021 IL App (1st) 200563, ¶ 30.)\nThe\nTims appellate court decision is not the last word on this statute of limitations issue. The defendant, which was supported on appeal by the Illinois Chamber of Commerce, could seek a discretionary appeal to the Illinois Supreme Court. Additionally, this same issue is now before the Illinois Appellate Court’s Third District in Marion v. Ring Container Technologies, LLC (though Marion is stayed pending the Illinois Supreme Court’s decision in McDonald v. Symphony Bronzeville Park LLC regarding the applicability of the Illinois Workers’ Compensation Act to certain BIPA claims). The Tims court also did not address when BIPA claims accrue (regardless of the limitations period), an issue pending before the federal Seventh Circuit Court of Appeals in Cothron v. White Castle System, Inc. This accrual issue, too, may be headed to the Illinois Supreme Court as a certified question.\nMeanwhile, companies doing business in Illinois that use biometric devices should continue to consider potential BIPA obligations. Virtually all trial courts to have addressed the issue applied the five-year statute of limitations to all BIPA subsections. Thus, a silver lining in an otherwise pro-plaintiff decision is the ruling that a one-year statute of limitations applies at least to\nsome BIPA claims. However, because under Tims, that one-year limitation does not apply to BIPA’s most frequently litigated provisions (Sections 15(a) and 15(b)), the tide of BIPA class action lawsuits should continue to flood Illinois state and federal court dockets.", "pred_label": "__label__POS", "pred_score_pos": 0.5027395486831665} +{"content": "All-solid state Li ion batteries are expected as one of next-generation rechargeable batteries since they have the potential to achieve high energy density and are free of risk of a flammable liquid electrolyte. The Li ion batteries cathodes, such as LiCoO\n2, change their volume during insertion or extraction of Li ions. Therefore, mechanical stress can be induced at the electrode/electrolyte interface. This mechanical stress can affect the thermodynamic and/or kinetic properties of electrodes and electrolytes. In this study, we aimed to understand the influence of the mechanical stress on Li chemical potential of LiCoO 2. The variation of Li chemical potential in LiCoO 2 under mechanical stress was evaluated by electromotive force (emf) measurements. Positive emf was observed when the external mechanical stress was applied. This indicates that Li chemical potential in LiCoO 2 was changed by the mechanical stress. The relationship between Li chemical potential and the mechanical stress was discussed from thermodynamic point of view.", "pred_label": "__label__POS", "pred_score_pos": 0.6397652626037598} +{"content": "Abstract : ZnO nanorods were grown on polyester fabric by hydrothermal process. The seeding of fabric to grow ZnO nanorods was necessary because they did not grow without seeding. An air plasma treatment was carried out on polyester fabric to generate polar groups which could attach ZnO seeds. ZnO nanorods were grown on these seeds. The generation of polar groups was confirmed by XPS analysis. The morphology of nanorods was characterized with SEM and TEM. The quantity of ZnO deposited on fabric in the form of nanorods was estimated to be 5.6 % w/w by atomic absorption spectroscopy. Two Gram negative bacteria; Escherichia coli and Pseudomonas aeruginosa and a Gram positive; Staphyloccocus aureus were used for antibacterial activity evaluation by qualitative method. E. coli and S. aureus were used for quantitative assessment by using NF ISO 20743:2009 Transfer Method. It was noted that the functionalized fabric prevented the growth of bacteria not only on and below the fabric but also in the immediate proximities for all three bacteria. It was also observed that the fabric was more effective against Gram positive as compared to Gram negative bacteria. Moreover, it was shown that UV pre-activation of functionalized fabric enhanced the antibacterial activity.", "pred_label": "__label__POS", "pred_score_pos": 0.6809011101722717} +{"content": "I was wrong to initiate field research in the Volcanic Tablelands and collect rock samples without explicit clearance from the local BLM authority. I recognize the error in my judgment and apologize to the local tribal groups, including members of the Bishop Paiute Tribe, for the impact of my actions.\nWhile the area’s geology is of significant interest, it is also of cultural and historical importance. I have always tried to conduct field research in a manner that is respectful of the land and its people. In this situation, I failed. I appreciate that I did not realize the damage I was causing at the time and that our efforts to assess the site for signs of petroglyphs and confirm that there were no prominent petroglyphs was not enough. There is no excuse for sampling without permission, and more broadly intruding on sacred land is wrong. I am horrified that I inadvertently collected samples from a sacred area that I too cherish and respect. I sincerely and deeply apologize for the disturbance we caused.\nFrom the moment I was notified and realized the violation and oversight, I have sought to make amends for my actions. I am committed to continuing to educate myself and to bringing awareness to others on how to conduct field work in a more responsible and respectful manner. There should be clear consent of land managers and indigenous people prior to engaging in field work. I hope that I can continue to make amends through my continued efforts to bring awareness to the significance of this matter.\nJoe Kirschvink California Institute of Technology July 2021", "pred_label": "__label__POS", "pred_score_pos": 0.8578444719314575} +{"content": "Abstract\nDespite there being numerous studies exploring the relationship between competition and vertical integration, the empirical findings regarding the nature of this relationship are still unclear. The current study suggests that technological niche width mediates the relationship between competition and vertical integration. It also suggests that technological niche width and vertical integration play a complementary role in enhancing firm performance. These arguments have found empirical support in the examination of the U.S. hybrid electric vehicle market from 2008 to 2016. In so doing, this study provides an opportunity to better understand the relationship between competition, vertical integration, and technological niche width. In addition, it explains how firms can effectively manage fierce competition and achieve the goal of superior performance through strategic decisions regarding vertical integration and technological niche width.\nKeywords competition firm performance hybrid electric vehicle market technological niche width vertical integration ASJC Scopus subject areas Business and International Management Geography, Planning and Development Strategy and Management Management, Monitoring, Policy and Law", "pred_label": "__label__POS", "pred_score_pos": 0.5893301367759705} +{"content": "Inclusion of disadvantaged parts of the society to the labor market is now becoming a major task for the policy makers. This task has multiple dimensions requiring integration of complex societal and engineering decisions. In this study, we will present G@together, a Urban Europe project funded by TUBITAK as an exemplary for an international, multi-stakeholder and interdisciplinary approach for finding solutions to societal challenges. This project aims facilitating the inclusion of qualified but disadvantaged individuals labor markets. We will particularly focus on the collaboration of engineers and social researchers to engage the users into the system design process. Our purpose is to develop a role management system that does not discriminate against any user group. For this purpose, we incorporate system design approach with social research process that involves a variety of methods. With this, we target to overcome the shortcomings of top-down designed expert systems which might have rule management features discriminating against disadvantaged groups. All stakeholders have participated to the design process to voice their concerns about user roles and management of the digital rights. After a series of consulting sessions involving engineers, stakeholders and social researchers and interviews with potential users, we have discovered that depersonalized application procedures would solve the asymmetrical rights management issue. (C) 2015 The Authors. Published by Elsevier Ltd.", "pred_label": "__label__POS", "pred_score_pos": 0.8661755919456482} +{"content": "While reviewing the Cleveland/Cuyahoga County Workforce Development Board’s most recent annual report, I was drawn to the OhioMeansJobs page.\nI learned my firm qualifies for funding short-term training for new employees. Workers may qualify for up to $7,500 to pay for short-term training, if training is required to get a job. Reimbursement to employers is 50% of the wage rate up to a maximum wage of $25 per hour.\nAccording to the report, workers have access to recruitment services, internet job postings, hiring and training incentives, layoff and dislocation services, and industry-specific labor market information.", "pred_label": "__label__POS", "pred_score_pos": 0.9938787221908569} +{"content": "President Biden signed the $1.9 trillion American Rescue Plan Act on March 11th, which means a third round of stimulus checks are on their way to Americans.\nMonths of negotiation in the House and Senate have left many people wondering if they qualify for this round of stimulus payments, how that eligibility is determined, and what can be done to ensure payments are received.\nWho Is Eligible For This Stimulus?\nWhile each adult and dependent will receive a $1400 check this round, unlike the previous stimulus payments where dependents only qualified for $500 and $600 respectively, the income limits for this round of stimulus payments are stricter than the previous one. Kari Brummond, a tax preparer and financial writer for TaxDebtHelp, says, \"To qualify for the full payment, individuals must have an adjusted gross income (AGI) of $75,000 or less, while couples filing jointly need an AGI of $150,000 or less and head-of-households need an AGI of $112,500 or less.\"\nWhat About Partial Payments?\nIn this round of stimulus payments, partial payments will be available for those just slightly above the limits. Brummond says, \"Taxpayers above these thresholds may receive a partial payment if they have an AGI of less than $80,000 for a single filer, less than $160,000 for married filing jointly, or less than $120,000 for head-of-households.\"\nWho Qualifies as a Dependent for This Stimulus?\nDuring the last round of stimulus payments, some dependents were excluded from eligibility, such as high school students over the age of 16, college students still claimed by the parents, elderly adult dependents, and disabled adult dependents.\nFor this third stimulus payment, Tricia Tetrault, Senior Financial Analyst at Fit Small Business and The Close, says, \"While previous stimulus payments did not account for adult dependents, the current proposal offers the same stipend for adult dependents as it does for dependent children.\"\nAre There Any Tips For Qualifying?\nSince your most recent tax returns will determine your eligibility, there is no way around the income requirements for this round of stimulus payments. However, there may be some strategies you can employ to help you qualify.\nYou may consider either filing your current tax returns quickly or hold off on filing them until closer to the deadline, depending on your income status. According to Tetrault, \"If you were previously ineligible for a stimulus payment based on your 2019 returns, but experienced a reduction in income in 2020, filing your 2020 tax return as soon as possible could benefit you.\"\nThis third stimulus payment comes at a crucial time for a lot of Americans: it's been one full year since the first lockdown of Covid, and many are suffering the financial impact of closed businesses, health issues, and even childcare and educational concerns. With the $1400 checks going to an estimated 85% of American households, the majority of taxpayers are eligible for the stimulus benefit. Checks are expected to begin arriving later this month.", "pred_label": "__label__POS", "pred_score_pos": 0.7966536283493042} +{"content": "A monohull form has been selected to minimise accelerations caused by roll motions, reflecting considerations that the SOV will be on DP 80% of the time at speeds between 0-5 knots. The bow section has been lowered to create a V-shape. This offers significantly reduced slamming, facilities inclusion and improved operation of the bow thrusters. The strong V-shape in the frames in the aft ship reduce slamming occurrence, while the concentration of volume in the midship region achieve a slender aft. Both features make stern to weather operations more comfortable than on a conventional PSV.\nThese innovations lead to increased, safer access to the wind energy sector, thereby contributing to lower energy costs. Seakeeping analysis of systematic variations of hull design and dimensions verified are by tank tests. More access, more comfort. Balanced low lateral wind profile and shallow draught contribute to reduced power demand while station-keeping in beam-on conditions. Focus on high-speed transits between turbines while remaining in DP. DP controllers, gangway systems and seakeeping characteristics assessed in hardware-in-the-loop (HIL) test. The HIL enables us to carry out a site specific assessment based on the local metocean data. This in turn gives the owner operator more certainty about the capabilities of the vessel.\nAccommodation areas are located amidships to minimise vertical accelerations (15% below a conventional PSV). The vessel accommodates engineers whose previous experience may be land-based. Avoidance of seasickness and perception of a comfortable working environment will influence their acceptance of extended stays at sea. Rest areas have been designed to improve life at sea and ensure readiness of personnel for work. Natural light has been maximised and the vessel will also feature a recreational space.View virtual tour\nThe primary access solution is a motion compensated access gangway system (Uptime) aligned with the vessel’s DP system. This gangway, in combination with the integrated elevator, offers safe and stepless access from the covered warehouse to the offshore structure. For a high level of redundancy, alternative transfer methods are included, including helicopter access and a daughter craft.Watch the video\nAll internal spaces have been designed with logistical or personnel flow in mind. A well routed workflow supports an improved working environment, yet preserves a high convenience level.", "pred_label": "__label__POS", "pred_score_pos": 0.7542097568511963} +{"content": "Target Ovarian Cancer will help you understand your role in diagnosing cancer at the earliest possible stage whatever your role in the primary care multi-disciplinary team.\nAs Primary Care teams diversity through the ARRS scheme, so do the opportunities and challenges of diagnosing ovarian cancer early. Our expert panel will support you to recognise symptomatic women, gain confidence in managing patients appropriately and offer simple guidance on best practice for safety netting patients effectively.\nThe expertise shared in this session is focused on ovarian cancer but many of the principles will support early diagnosis of other cancers.", "pred_label": "__label__POS", "pred_score_pos": 0.541770339012146} +{"content": "What Does a Pinched Nerve Feel Like?\nAbout 85 out of every 100,000 adults in the United States will experience a pinched nerve each year. In fact, a pinched nerve could potentially be the root cause of your pain. But how do you know? What does a pinched nerve feel like?\nIn this article, we’ll explore what exactly having a pinched nerve means, the symptoms of a pinched nerve, the causes of a pinched nerve, and how you can treat and prevent it. Let’s get straight to it!\nWhat is a Pinched Nerve?\nA pinched nerve is when a nerve comes under pressure due to surrounding structures or tissue. This can happen due to tight muscle, muscle spasms, inflammation, injury, and more. And this can happen at various spots in the human body.\nA pinched nerve can occur in your wrist, lower back, neck, buttocks, and more. For example, sciatica is a common form of low back pain caused by a pinched nerve. The sciatic nerve runs down the legs. However, this nerve can come under pressure in the lower back or buttocks. A common example includes a tight piriformis muscle or a spastic piriformis muscle. The piriformis muscle is a tiny muscle located in the buttocks. When it becomes aggravated, it can cause problems. It may press on the sciatic nerve, leading to pain, tingling, numbness, and weakness in the legs.\nPinched Nerve Symptoms\nSo, what does a pinched nerve feel like? How do you know that’s what is causing your pain?\nTypical pinched nerve symptoms include:\nReduce sensation or numbness in the area that the nerve serves Burning, sharp, or aching pain Radiating pain Pins and needles or tingling sensations Muscle weakness\nSometimes, individuals describe some of these symptoms as though their leg or hand has fallen asleep. Most people have felt similar sensations when they’ve laid on their hand or arm for too long or have crossed their legs for an extended period.\nPinched Nerve Causes\nAs previously mentioned above, a pinched nerve occurs when a nerve is compressed. This can happen due to:\nInjury Arthritis Muscle tension or spasm Stress Overuse Obesity Other underlying conditions, such as a herniated disc Treatment Options\nGenerally, treatment varies depending on what is causing your pinched nerve in the first place. However, in most cases, rest is recommended to prevent further aggravation and to allow time for your body to heal.\nCommon treatment options include:\nIce and Heat\nThis can help reduce pain and inflammation and lower any muscular tension contributing to your pinched nerve. Place the ice or heat on the area for 10–20 minutes at a time. You can choose whichever option feels best, or you can alternate between the two.\nOver-the-Counter Pain Relievers\nThese can help reduce your symptoms. However, NSAIDs, non-steroidal anti-inflammatory drugs, should never be taken longer than two weeks at a time.\nPhysical Therapy\nA physical therapist can prescribe appropriate exercises to help alleviate your condition. They can further perform various manual therapy techniques that can help reduce your symptoms.\nSplints or Cervical Collars\nIf re-aggravating the area is an issue, it may be wise to invest in a splint or cervical collar to immobilize the area and give the irritated area time to rest and heal.\nSurgery\nThis is often the last resort. If a pinched nerve hasn’t improved after months of treatment and after various treatment methods, your doctor may recommend surgery to remove the pressure on your nerve. Surgery may also involve removing any structures that are aggravating the nerve.\nPreventing a Pinched Nerve\nAs always, prevention is the best form of treatment. If you can halt pain before it happens, you’re always better off.\nWhen it comes to a pinched nerve, you’ll want to focus on maintaining a good posture. This means sitting with your shoulders back and down, your feet planted on the ground, and your neck straight (this means no hunching over to look at a phone or work on your computer).\nFurther, maintaining a regular exercise routine involving flexibility exercises can go a long way. These can help reduce your risk of injury, which may lead to a pinched nerve.\nIf you’re performing repetitive activities, ensure you take plenty of breaks. Give your body time to rest and reset. This includes typing at your keyboard. You can also support your body during these activities. For instance, for typing, you can use wrist supports to ensure your wrist maintains a healthy position that is less likely to cause pain.\nLastly, maintain a healthy weight. Excess weight can place pressure on parts of the body, ultimately leading to a pinched nerve.\nPrevent pain before it becomes a problem. Use the tips above to help you do just that. And if you’re already experiencing a pinched nerve, seek out the right treatment for it. This may involve visiting your family doctor or your local physical therapist. Get on track toward healing today!", "pred_label": "__label__POS", "pred_score_pos": 0.8955036997795105} +{"content": "Over the year, the crypto-verse has seen some major pumps and dumps driven by FUDs which have severely affected the prices of tokens. Heck, even Bitcoin was not spared the wrath of FUDs, let alone meme coins like Dogecoin and Shiba Inu. However, one alt that has shown some resistance to the same is Litecoin.\nThe price of Litecoin spiked swiftly early on Monday, before falling back, after a news release touting a partnership with retail giant Walmart Inc. turned out to be fake. Nonetheless, despite the rest of the market being fairly lukewarm at press time, LTC was notably holding up better than the rest.\nWhat has helped hold this currency’s price?\nLTC’s OG coin club status\nLitecoin, at one point, was valued at $240, up by almost 40%, after the issuance of a press release that touted a Litecoin-Walmart partnership. The altcoin’s trade volumes also saw their highest peak since 19 May. Alas, these numbers quickly fell after Walmart clarified that the news release was fraudulent.\nWhile this definitely came as a blow, it was notable that LTC’s price didn’t drastically fall post the FUD.\nFor Litecoin, however, some good news followed a couple of days later. AMC made headlines by announcing it will support Bitcoin Cash, Ethereum, and Litecoin. While ETH and BCH’s prices didn’t note much of an impact, LTC’s price has strongly held on to the $170-support level.\nIt is possible then that Litecoin has held on so well since it is part of the OG coins’ club that has been around for a long time. Apart from that, the constant support by institutions has enabled its growth.\nEven so, LTC’s metrics seemed to be painting a two-sided picture for the altcoin.\nHere’s the metrics’ verdict…\nWhile active addresses for LTC were at an ATH on 8 September, they took a downturn soon after. The after-effects of the FUD weren’t as evident as active addresses were still higher than the numbers seen last year. The downtick in active addresses also saw signs of reversal post the FUD news as they were seen forming a V-shaped recovery curve.\nFurther, the aSOPR and dormancy highlighted contrasting patterns. Dormancy showed that older coins were in circulation – A bad sign for the price. What’s more, the aSOPR on different averages highlighted that profits are being realized.\nEven with Litecoin’s price dropping at press time, its aSOPR was trending higher. This implied that profits are being realized with potential for previously illiquid supply being returned to liquid circulation.\nThus, while LTC’s mid-short-term trajectory looks like it may face certain bumps due to the larger market going down, long-term prospects look good. Further, LTC’s resistance from the FUD was proof of Litecoin’s market strength.", "pred_label": "__label__POS", "pred_score_pos": 0.635130763053894} +{"content": "A platform of large-scale\nin vivo CRISPR screens is described in Science this week. Despite CRISPR-Cas9's ability to be scaled up for large-scale screens in cultured cells, its use in animals is limited by the need to generate, validate, and track large numbers of mutant animals. To address this, a University of Utah team developed MIC-Drop — short for multiplexed intermixed CRISPR droplets — that combines droplet microfluidics, single-need en masse CRISPR ribonucleoprotein infections, and DNA barcoding to enable large-scale functional genetics screens in zebrafish. \"The MIC-Drop platform enables in vivo vertebrate CRISPR experiments to be performed with speed, efficiency, and scale previously available only to in vitro systems,\" the authors write.\nAn analysis of the seadragon genome is published in\nScience Advances this week, providing insights into this animal's evolutionary novelties and identifying its sex-determining locus. Seadragons are best known for their leaf-like appendages, toothless tubular mouth, and male pregnancy involving incubation of fertilized eggs on an open brood patch. To better understand the basis for such characteristics, a group led by scientists from the Chinese Academy of Sciences generated and analyzed high-quality, chromosome-level genome assemblies of the male and a female common seadragon, as well as a chromosome-scale, genome assembly for the closely related alligator pipefish. Transcription profiles show that a set of genes typically involved in fin development have been co-opted for the development of the seadragon's leaf-like appendages, as well as reveal an enrichment of transcripts for potential tissue repair and immune defense genes. The investigators also identify a putative sex-determining locus encoding a male-specific gene shared by common seadragon and alligator pipefish.", "pred_label": "__label__POS", "pred_score_pos": 0.5870561599731445} +{"content": "In a new draft guidance issued today the FDA sought to clear up confusion about what types of changes to existing medical devices require new 510(k) submissions.\nThe watchdog agency outlined changes to the device features, such as labeling, manufacturing and materials, which require a new 510(k) submission, as well as what types of changes don’t need additional agency review.\n\"We are making the regulatory process for medical devices less challenging by better describing our expectations,\" Dr. Jeffrey Shuren, director of FDA’s Center for Devices & Radiological Health, said in a press release. \"In particular, manufacturers can continue to make innovative improvements to their devices and better plan for any updated submissions. This saves time and money.\"\nThe guidance addresses types of changes that typically warrant a new 510(k) submission for an existing medical device:\nMajor changes or modifications to the intended use of the device. Manufacturing process changes. Specific types of labeling changes. Technology, engineering and performance changes. Materials changes. Is clinical data necessary to determine substantial equivalence?\nThe document, titled\nDeciding When to Submit a 510(k) for a Change to an Existing 510(k), replaces the 1997 guidance of the same name, which was issued to clarify the words \"significant\" and \"major\" in regard to agency regulation stating that existing devices need new applications in case of:\n(i) A change or modification in the device that could significantly affect the safety or effectiveness of the device, e.g., a significant change or modification in design, material, chemical composition, energy source, or manufacturing process.\n(ii) A major change or modification in the intended use of the device.\"\nThe guidance does not address issues concerning nanotechnology, and the FDA recommends that manufacturers contact the agency directly to work out any nano-related changes.", "pred_label": "__label__POS", "pred_score_pos": 0.5460985898971558} +{"content": "As of Friday, B.C. drivers once again need snow tires to travel on most of the province's highways.\nThe province requires passenger vehicles using major roadways be equipped with winter tires between Oct. 1 and March 31 every year, to account for more hazardous weather.\nThe annual requirement covers:\nAll highways in the North;\nAll highways in the Interior;\nSections of some highways on the South Coast, including the Sea to Sky Highway; and\nSections of some highways on Vancouver Island, including the Malahat and highways 4, 14 and 28.\nTrucks travelling these routes are also required to carry chains.\nFor select highways, the date is extended until April 30 to account for early spring snowfall. The province said these highways, including mountain passes and rural routes in heavy snowfall areas, are marked with regulatory signs.\nLook for the snowflake or M+S\nWinter tires — sometimes called alpine or snow tires — are marked with a symbol of a snowflake inside a three-peaked mountain placed on the sidewall of the tire.\nMud and snow tires, marked with an M+S symbol, also qualify as winter tires, though the Ministry of Transportation notes they are less effective than dedicated alpine snow tires.\nThe ministry requires winter tires to have tread at least 3.5 millimetres deep. It requires at least two matching winter tires on the vehicle's drive axle, but recommends a matching set on all wheels.\nDrivers without proper winter tires in good condition caught driving on designated highways can be fined $121.\nA full list of routes requiring winter tires can be found on the ministry website.", "pred_label": "__label__POS", "pred_score_pos": 0.8814373016357422} +{"content": "Browsing Research Output by Author \"Osei-Frimpong, Kofi\" An examination of the influence of ICT on patient co-creation in healthcare service delivery at the micro levelOsei-Frimpong, Kofi; Wilson, Alan; Lemke, Fred (2016)This study provides an empirical perspective of the influence of online health information search on patient co-creation in healthcare service delivery at the micro level. The study primarily sheds light on the influence of information seeking on the clinical encounter process and how this cumulatively impacts on the expected service outcomes. The following research questions are addressed: 1. How do patients search for information and what motivates them to seek health related information? 2. What impact does online information seeking have on patients’ engagement in healthcare clinical encounters? 3. How is co-creation modeled in healthcare to ascertain the cumulative effects of ICT on the expected outcomes at the micro level? Customer coproduction in healthcare service delivery: Examining the influencing effects of the social contextOsei-Frimpong, Kofi; McLean, Graeme; Wilson, Alan; Lemke, Fred (Journal of Business Research, 2020)This study furthers our understanding of service coproduction by examining some pertinent antecedents and the consequent effect on customer adherence to medical instructions in healthcare service delivery. Through a cross-sectional quantitative survey design, data collected from 594 healthcare customers were analysed through structural equation modelling using AMOS 23. The findings indicate significant influences of social context on participation in service coproduction and adherence. Additionally, the mediating effect of customer role clarity on social context (nature of interactions, access to healthcare information, service climate) and coproduction are established. This study also determined moderation effects of provider-customer orientation on the coproduction process. Further, customer health condition-type (acute or chronic) does not present different effects on their coproduction behaviours. From a social cognitive theoretical perspective, this study has established that customers’ coproduction behaviours are motivated by the social system in relation to the social context. Examining the service engagement process in value co-creation in healthcare service delivery: A multi-level perspectiveOsei-Frimpong, Kofi; Wilson, A.; Lemke, Fred; Mclean, G. (2018)This study furthers our understanding of value co-creation, which has received little attention in the doctor-patient encounter relationship. We employed a quantitative survey method to shed light on factors driving this fundamental service aspect, followed up with a multilevel data analysis. These factors (assurance, social skills, doctor-patient orientation) from the doctor significantly strengthen the effects of the patient-level factors (trust, perceptual beliefs, interactions) on the service engagement and outcomes of the focal doctorpatient dyad. We establish the cross-level interactive effects at the group level of the focal dyad on service engagement. The findings suggest service engagement at the group level had no significant effect on patients’ perceived value. We provide new empirical insights to understand and operationalize these fundamental influencing factors of the value co-creation concept in a healthcare setting, and contribute to the value co-creation literature.", "pred_label": "__label__POS", "pred_score_pos": 0.5866156816482544} +{"content": "Mortality > Table\nRate/Trend Comparison by Cancer Table\nAbove US Rate Similar to US Rate Below US Rate Rising\nTrend\nPriority 1: rising and above Priority 2: rising and similar Priority 3: rising and below Stable\nTrend\nPriority 4: stable and above\nMilam County\nPotter County\nPriority 6: stable and similar\nBexar County\nHarris County\nRusk County\nSmith County\nTom Green County\nTravis County\nVal Verde County\nWebb County\nPriority 7: stable and below Falling\nTrend\nPriority 5: falling and above Priority 8: falling and similar\nAnderson County\nAngelina County\nAransas County\nAustin County\nBastrop County\nBell County\nBowie County\nBrazoria County\nBrazos County\nBrown County\nBurnet County\nCaldwell County\nCherokee County\nComal County\nCooke County\nDallas County\nEctor County\nEl Paso County\nEllis County\nGalveston County\nGillespie County\nGrayson County\nGregg County\nGuadalupe County\nHardin County\nHays County\nHill County\nHood County\nHunt County\nJasper County\nJefferson County\nJohnson County\nKaufman County\nKerr County\nLamar County\nLiberty County\nLlano County\nLubbock County\nMcLennan County\nMedina County\nMidland County\nNacogdoches County\nNueces County\nOrange County\nPolk County\nRandall County\nSan Patricio County\nTarrant County\nTaylor County\nUpshur County\nVan Zandt County\nVictoria County\nWalker County\nWashington County\nWharton County\nWichita County\nWilliamson County\nPriority 9: falling and below\nCameron County\nCollin County\nDenton County\nFort Bend County\nHarrison County\nHenderson County\nHidalgo County\nMontgomery County\nParker County\nWood County\nNotes:\nCreated by statecancerprofiles.cancer.gov on 10/16/2021 5:46 am.\n1 Priority indices were created by ordering from rates that are rising and above the comparison rate to rates that are falling and below the comparison rate. 2 Recent trend in death rates is usually an Average Annual Percent Change (AAPC) based on the APCs calculated by Joinpoint Version 4.8.0.0. Due to data availability issues, the time period and/or calculation method used in the calculation of the trends may differ for selected geographic areas. 3 Rate ratio is the county rate divided by the US rate. Previous versions of this table used one-year rates for states and five-year rates for counties. As of June 2018, only five-year rates are used.\nSource: Death data provided by the National Vital Statistics System public use data file. Death rates calculated by the National Cancer Institute using SEER*Stat. Death rates are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84, 85+). The Healthy People 2020 goals are based on rates adjusted using different methods but the differences should be minimal. Population counts for denominators are based on Census populations as modified by NCI. The 1969-2018 US Population Data File is used with mortality data.\nNote: When the population size for a denominator is small, the rates may be unstable. A rate is unstable when a small change in the numerator (e.g., only one or two additional cases) has a dramatic effect on the calculated rate. Suppression is used to avoid misinterpretation when rates are unstable.\nState Cancer Registries may provide more current or more local data. Data presented on the State Cancer Profiles Web Site may differ from statistics reported by the State Cancer Registries (for more information).\nData for the following has been suppressed to ensure confidentiality and stability of rate and trend estimates:\nAndrews County, Archer County, Armstrong County, Bailey County, Baylor County, Bee County, Blanco County, Borden County, Bosque County, Brewster County, Briscoe County, Brooks County, Burleson County, Calhoun County, Callahan County, Camp County, Carson County, Castro County, Chambers County, Childress County, Clay County, Cochran County, Coke County, Coleman County, Collingsworth County, Colorado County, Comanche County, Concho County, Cottle County, Crane County, Crockett County, Crosby County, Culberson County, Dallam County, Dawson County, DeWitt County, Deaf Smith County, Delta County, Dickens County, Dimmit County, Donley County, Duval County, Eastland County, Edwards County, Erath County, Falls County, Fannin County, Fayette County, Fisher County, Floyd County, Foard County, Franklin County, Freestone County, Frio County, Gaines County, Garza County, Glasscock County, Goliad County, Gonzales County, Gray County, Grimes County, Hale County, Hall County, Hamilton County, Hansford County, Hardeman County, Hartley County, Haskell County, Hemphill County, Hockley County, Houston County, Howard County, Hudspeth County, Hutchinson County, Irion County, Jack County, Jackson County, Jeff Davis County, Jim Hogg County, Jim Wells County, Jones County, Karnes County, Kenedy County, Kent County, Kimble County, King County, Kinney County, Kleberg County, Knox County, La Salle County, Lamb County, Lampasas County, Lavaca County, Lee County, Leon County, Limestone County, Lipscomb County, Live Oak County, Loving County, Lynn County, Madison County, Marion County, Martin County, Mason County, McCulloch County, McMullen County, Menard County, Mills County, Mitchell County, Montague County, Moore County, Morris County, Motley County, Newton County, Nolan County, Ochiltree County, Oldham County, Palo Pinto County, Panola County, Parmer County, Pecos County, Presidio County, Rains County, Reagan County, Real County, Red River County, Reeves County, Refugio County, Roberts County, Runnels County, Sabine County, San Augustine County, San Saba County, Schleicher County, Shackelford County, Shelby County, Sherman County, Somervell County, Stephens County, Sterling County, Stonewall County, Sutton County, Swisher County, Terrell County, Terry County, Throckmorton County, Titus County, Trinity County, Upton County, Uvalde County, Ward County, Wheeler County, Wilbarger County, Willacy County, Winkler County, Yoakum County, Young County, Zapata County, Zavala County\nTrend for the following could not be reliably determined due to small number of deaths per year:\nAtascosa County, Bandera County, Cass County, Coryell County, Hopkins County, Kendall County, Matagorda County, Maverick County, Navarro County, Robertson County, Rockwall County, San Jacinto County, Scurry County, Starr County, Tyler County, Waller County, Wilson County, Wise County\nInterpret Rankings provides insight into interpreting cancer statistics. When the population size for a denominator is small, the rates may be unstable. A rate is unstable when a small change in the numerator (e.g., only one or two additional cases) has a dramatic effect on the calculated rate.\nData for United States does not include Puerto Rico.", "pred_label": "__label__POS", "pred_score_pos": 0.9010717272758484} +{"content": "Residing near Mount Asama of Nagano Prefecture, Symbiotic House is composed of two geometric concrete volumes. Blending themselves into the courtyard’s grey pebbles, their symmetrically slanted roofs mimic the mountainous peak in the distance. Parallel to each other, they seem to be having a conversation in the verdant surroundings, which are graced with beams of sunlight shining through tall canopies. These nature blessings make a perfect site for a resting home, where quietness is filled with the sounds of morning birds and late-night insects.\nSymbiotic House was built for an elderly couple to spend the rest of their years. The tranquil ageing process is in dialogue with the forest, which can be observed from all sides of the interior. Full-height glass facades complement the rough concrete surface to lighten the inside, bringing natural light onto the wooden floors and furniture. The addition of organic textures and a brown palette gives cosy warmth to the stark interior. At some corners, house plants curve and rise like rhythms of a harmonic life.\nWhereas the larger structure is dedicated to the couple, the smaller volume acts as a unit for their children and grandkids. The two masses are connected with a small corridor that overlooks a budding garden. While maintaining privacy, the corridor is an interstitial space that helps flow living activities from one side to another. It modestly stabilizes physical separation and generational differences, linking passages of time-continuous and endless.\nAs a considerate gesture, the architects dedicated a room adorned with traditional elements, including tatami mats, tokonoma, and paper screens. At moments throughout the property, small details like a conventional tsukubai adorn corners with a touch of nostalgia. These intricate instances act as memories for the residents and valuable relics for the modern time.\nSymbiotic House is a residence filled with complex emotions. Time stops to give people across generations a moment to enjoy the beauty of life. A three-dimensional snapshot of history, the house records human movements and sentiments through physical linkage. At times, a simple gesture is all it needs to ignite all the senses within one.", "pred_label": "__label__POS", "pred_score_pos": 0.9095736145973206} +{"content": "The Computational Social Science Technical Skills Workshop (or Computation Skills Workshop for short) trains participants in technical skills and methods which are relevant to computationally-driven research, but are not typically taught in for-credit courses. It provides an explicit introduction to core software environments and interfaces which impose a barrier to access for individuals lacking prior exposure to programming, and facilitates a community of computational researchers across the Division of the Social Sciences. Individual workshops are designed for a range of technical backgrounds, including purely introductory methods as well as intermediate or advanced training in specific software or computational techniques. Workshops are designed for hands-on learning, and will include substantial live-coding exercises.\nThe workshop launched in 2021 on a biweekly schedule. Future meetings will include extended length workshops devoted to a broad range of tools and software in the data science community. All workshop materials, including detailed notes, slides, and in-class exercises, are published under open-source license.", "pred_label": "__label__POS", "pred_score_pos": 0.9967466592788696} +{"content": "A set of five gold complexes with the general formula Au(PR\n3)(C≡C-C 6H 4-4-R') (R = PPh 3, R' = -CHO (1), R = PCy 3, R' = -CHO (2), R = PPh 3, R' = -N=CH-C 6H 4-2-OH (3), R = PPh 3, R' = -N=CH-C 6H 4-4-OH (4), R = PCy 3, R' = -N=CH-C 6H 4-2-OH (5)) were synthesized and characterized by elemental analysis, 1H-NMR spectroscopy, 31P-NMR spectroscopy, and mass spectrometry. The structures of complexes 2 and 5 were determined by X-ray crystallography. The effects of the structural modifications on the protein binding affinities and anticancer activities of the five gold complexes were assessed. Fluorescence quenching experiments to assess binding to human serum albumin (HSA) revealed that the Schiff base complexes (3, 4, and 5) had binding constants that were superior to their parent aldehyde complexes and highlighted the position of the hydroxy group because complex 4 (4-hydroxy) had a binding constant 6400 times higher than complex 3 (2-hydroxy). The anticancer activities of the complexes against the OVCAR-3 (ovarian carcinoma) and HOP-62 (non-small-cell lung) cancer cell lines showed that the Schiff bases (3-5) were more cytotoxic than the aldehyde-containing complexes (1 and 2). Notably, compound 4 had cytotoxic activity comparable to that of cisplatin against OVCAR-3, demonstrating the significance of the para position for the hydroxy group. Molecular docking studies against the enzyme thioredoxin reductase (TrxR) and human serum albumin were conducted, with docking scores in good agreement with the experimental data. The current study highlights how small structural modifications can alter physiochemical and anticancer properties. Moreover, this simple design strategy using the aldehyde group can generate extensive opportunities to explore new gold(I)-based anticancer drugs via condensation, cyclization, or nucleophilic addition reactions of the aldehyde. Keywords: HSA-binding; anticancer properties; gold(I); molecular docking; phosphine.", "pred_label": "__label__POS", "pred_score_pos": 0.6322996616363525} +{"content": "Madrid, the first Spanish city to implement a comprehensive sustainability tool for meetings and events\nSustainability, legacy and positive impact are three key aspects of Madrid’s MICE tourism strategy. And, thanks to the recent addition of this new tool, these three pillars will be integrated into professional conferences and events held in the capital. The Tourism Department, in collaboration with Madrid Convention Bureau (MCB), has launched PLUS (Platform for Legacy with us). The first of its kind in Spain, this digital platform aims to support organisers manage these types of events efficiently and in line with the 17 Sustainable Development Goals (SDGs) adopted by the United Nations (UN) in the 2030 Agenda.\nPLUS generates sustainability reports specific to each meeting that takes place in Madrid, with recommendations for how to minimise social and environmental impact. What is so innovative about this analysis is that it is conducted before events are held, allowing for organisers to make any necessary changes in the planning phase to reduce impact from the outset. The report also facilitates implementation of the SDGs in real time and the creation of a legacy strategy.\nThanks to this tool, event organisers are able to evaluate a series of aspects about the event during the design phase. What’s more, the various reports are adapted to each event’s specific characteristics, i.e., attendees, venues, type of layout and set-up, catering services, etc. Additionally, the platform also generates a post-meeting report, which calculates the total CO2 emissions and, in a later phase, will suggest ways to compensate the event’s impact on a local level within the city of Madrid.\nLegacy project\nOne of the main features of this new service is related to creating legacy, by promoting contact between event organisers and local agents (NGOs, associations, foundations, etc.). In this way, it encourages positive impact actions from a social, environmental and cultural point of view, giving way to long-lasting benefits for society. To do so, the tool features a specific section to connect event organisers with representatives from a range of organisations located in Madrid, suggesting actions to contribute to this legacy project in the city.\nAvailable in Spanish and English, PLUS can be used to upload any necessary documentation to the ISO 20121 management system and to view statistics on sustainable events. It also includes a database for sustainable meetings with environmentally friendly resources, such as a list of Madrid-based suppliers of sustainable services and products which meet the SDGs. Madrid Convention Bureau will allow all organisers and companies responsible for managing conferences and events in the capital temporary access to the tool. Additionally, MCB will run free training sessions for its partners, targeting DMCs and PCOs, to promote the advantages and benefits of using this digital platform.\nMICE Sustainability Guide\nThis tool is a complement to the MICE Sustainability Guide, created by Madrid Convention Bureau in 2020 with practical information regarding sustainability, legacy and positive impact. Designed in collaboration with responsible tourism experts, this manual features an in-depth analysis of the Sustainable Development Goals related to the tourism industry, with practical ways to apply them in five different sectors: Special Venues, Hotels, Restaurants and Catering, Service Providers and Events Agencies, Specialist Travel Agents (DMCs), and Professional Conference Organisers (PCOs).\nWith initiatives like these, Tourism Department and MCB aim to consolidate Madrid’s reputation as a leading international MICE tourism destination and a sustainable, efficient and responsible city.", "pred_label": "__label__POS", "pred_score_pos": 0.8399951457977295} +{"content": "Who can use nicotine pouches (e.g. Velo, Lyft & Zyn) Those who are currently smoking (to prevent nicotine withdrawal and as a safer alternative to smoking) Those who have quit smoking (to prevent returning to smoking) They should not be used by people who have never smoked. What are in nicotine pouches?\nNicotine, water, plant-based ingredients, flavourings, and sweeteners are all used in this product. They don’t have any tob. in them.\nHow do I use a nicotine pouch?\nTake one out of the tin. Place it between your gum and lip. You’ll feel a tingling, hot sensation – that’s the nicotine being released. You can gently chew it a few times to release the nicotine. Keep the pouch between your gum and lip for a minimum of 5 minutes and a maximum of 60 minutes. DON’T SWALLOW IT.\nWhat nicotine strength should I use? Velo and Lyft have distinct strengths (Velo & Lyft: 4 mg, 6 mg) and Zyn has a separate strength (‘strong 2’=3 mg). ‘strength 4′ equals 6mg Start with the greater strength if you’re a heavy smoker (20+ cig. each day). Request a lower strength if it feels too strong. Try the lower strength if you only smo. 20 cig. per day. If it still doesn’t satisfy your want to smo., request a stronger dose. How often should I use a pouch?\nIf you keep the pouch in your mouth for up to 60 minutes each time, you shouldn’t require more than one every hour. A tin should keep you going for 1-2 days.\nWhat side effects might I get?\nSimilar to other oral nicotine replacements like lozenges and mouth spray, you might get hiccups or a sore mouth. If you have too many, you might feel sick and get an upset stomach.\nSafety tips: To prevent infection DO NOT share a pouch with anyone or use a pouch that someone has thrown away. If you accidently swallow a pouch, let the staff know straight away. Throw away the used pouch in the waste compartment in the top of the tin. Or throw it in a bin", "pred_label": "__label__POS", "pred_score_pos": 0.6624281406402588} +{"content": "However, there are several areas of severe storms research in which observations have been and will continue to be crucial toward advancing our understanding, such as the microphysical attributes of storms, cold pool properties, and the radiative effects of cloud shading. It seems only fitting, given that Lance Bosart is an observationalist's observationalist, that my talk focus on the critical role of observations in severe storms research, with special emphasis on what we have learned from observations that we could not have learned from numerical models alone.", "pred_label": "__label__POS", "pred_score_pos": 0.5466500520706177} +{"content": "To assist Nigerian entrepreneurs, start-ups and corporate customers scale their businesses, Nigeria’s leading digital bank, ALAT by Wema, has launched Quick Loan.\nThe additional feature which is hosted on ALAT for Business, its corporate internet banking platform, will help small/medium-scale enterprises (SME) and corporate customers access loans between N100,000 to N10,000,000.\nQuick Loan will enable ALAT for Business users to access loan services virtually from any location without the need to locate a physical branch. A Nigeria SME survey report developed by PricewaterhouseCoopers (PwC), shows there are about 17.4 million small and medium-scale enterprises (SMEs) in Nigeria and these contribute about 48% of the national GDP, accounting for 96 per cent of businesses and 84% of employment in the country.\nProduct Manager ALAT for Business, Samuel Robson, highlighted the pivotal role that SMES play in the economic, employment and export growth in Nigeria.\nHowever: “despite the significant contribution of SMEs to the Nigerian economy, challenges persist that hinder the growth and development of the sector,” said Robson.\nIn his statement, he stressed that “loan access has been one of the most challenging factors faced by this sector and we understand the need to support SMEs by providing easy access to the loans they seek.\n“Hence the launch of Quick Loan on ALAT for Business, a platform that currently serves our corporate customers and SME owners. We believe this extra feature will help to mitigate some hassles entrepreneurs and businesses experience.\nThe ALAT for Business Quick Loan is open to new and existing customers registered on the ALAT for Business platform and does not require cumbersome paperwork. The feature, Quick Loan, is specially designed for our corporate customers and SME owners,” Robson explained.\nALAT for Business is the internet banking platform designed to help corporate customers and entrepreneurs manage their business accounts optimally and stay on top of their finances from anywhere and anytime. Customers can make transactions of up to N100 million, make bulk transfers, pay bills and other collections without hidden charges, among others.\nALAT by Wema has continuously supported entrepreneurs, young startup founders, business, and SME owners in various capacities over the years. This year, the digital bank has facilitated the ALAT Talk Series, a session aimed at training young Nigerians on business management, strategy, technology and other key business areas.", "pred_label": "__label__POS", "pred_score_pos": 0.7405262589454651} +{"content": "2 Works\nIntraspecific competition plays a significant role in shaping how animals use and share habitats in space and time. However, the way individuals may modify their diel activity in response to increased competition has received limited attention. We used juvenile (age 1+) Arctic charr Salvelinus alpinus to test the prediction that individuals at high population density are more active and distribute their foraging activity over a greater portion of the 24-h cycle than individuals at low...\nData from: Divergence of gastropod life history in contrasting thermal environments in a geothermal lakeMagnus P. Johansson, Friederike Ermold, Bjarni K. Kristjánsson & Anssi Laurila\nExperiments using natural populations have provided mixed support for thermal adaptation models, probably because the conditions are often confounded with additional environmental factors like seasonality. The contrasting geothermal environments within Lake Mývatn, northern Iceland, provide a unique opportunity to evaluate thermal adaptation models using closely located natural populations. We conducted laboratory common garden and field reciprocal transplant experiments to investigate how thermal origin influences the life history of Radix balthica snails originating from stable cold...", "pred_label": "__label__POS", "pred_score_pos": 0.9998482465744019} +{"content": "Tree Pruning in San Marcos, CA\nRegular tree pruning can improve the health, appearance, and safety of trees. As an experienced\narborist company, we can determine the correct type of pruning that the trees on your property may need. Pruning may involve:\nEliminating branches that rub against each other.\nRemoving dead, dying, or weak limbs. Removing limbs that interfere with wires, buildings, gutters, roofs, chimneys, and windows or obstruct streets or sidewalks. Removing diseased or insect-infested limbs. Creating a better structure by thinning or making proper reduction cuts in order to lessen wind resistance and reduce the potential for storm damage. Training young trees to grow into well-structured trees. Removing branches or thinning to increase light penetration. Improving the shape and aesthetics. What’s the Difference Between Pruning and Trimming?\nTree trimming services include thinning off overgrown branches, which aids in the formation of shapely growth. In contrast, tree pruning protects against pests and illnesses while also promoting healthy development. It essentially entails removing dead, diseased, and lose branches that impede the trees' growth.\nWhat Trees Should Be Pruned?\nMany species of trees may require regular pruning to preserve the overall health of the tree. During specific seasons certain types of trees are pruned to prevent the tree from becoming overstressed.\nFor example, most Pinus (Pine) or Quercus (Oak) family trees should be pruned only during the dormant season.\nFaster-growing trees may need more regular pruning than slower-growing trees. Tree pruning also may depend on the tree's area, whether it's near a structure or in a more open space.\nWe also offer fruit tree pruning, which may vary depending on the season and desired goal for the tree. Fruit trees may benefit from summer pruning to maintain a specific size and prevent the accidental removal of fruiting buds for certain species. Some fruit trees produce fruit on current years’ development, and some have fruit on last years’ growth, and we can help you make the right decision that is best for your trees.\nPalm Tree Pruning\nPruning\nPalm trees will enhance their appearance, eliminate potential fire hazards, and remove seeds/seedpods that produce fruit that can cause a mess and attract pests. However, we recommend leaving a reasonable amount of healthy fronds to maintain the tree’s health.\nRemember that Palm fronds are the tree’s solar panels, and over trimming Palm trees may harm their health.\nStructural Pruning\nStructural pruning encourages a specific growth pattern by removing select branches that may be undesirable or problematic. It is necessary, especially for young trees, to help your tree’s overall well-being and prevent potential problems early on.\nThinning\nThinning involves removing select living branches from the tree’s interior or ends of branches to reduce weight, increase sunlight to the inner canopy, reduce wind resistance, and encourage an even distribution of foliage within the canopy.\nCrown Cleaning\nCrown cleaning involves removing dead, diseased, detached, and broken limbs to mitigate the risk of hazards and control the spread of decay, disease, or insects.\nCrown Reduction/branch reduction\nThis method is performed by reducing the overall size of the canopy by making proper reduction cuts to reduce end weight and create a more balanced canopy. This may help mitigate hazardous trees/branches and create a more uniform appearance.\nCrown Restoration\nThis tree pruning method seeks to restore a lost structure due to improper pruning, topping, storm damage, or other damage. It includes thinning out sucker branches or stubs to create a new branch union that is not overcrowded or structurally unsound. It may also involve reducing sucker leaders that have overgrown to a hazardous height.", "pred_label": "__label__POS", "pred_score_pos": 0.8856254816055298} +{"content": "As foreshadowed here the superannuation concession changes announced in the 2016-2017 Commonwealth Budget are to be reviewed before legislation is introduced.\nThe Treasurer has confirmed that there will be an exemption from the $500,000 lifetime cap on non-concessional (after-tax) contributions for self-managed superannuation funds who had pre-existing contracts and were relying on non-concessional contributions.\nThere is also expected to be an exemption to the cap for “life events”, such as an inheritance, a divorce settlement, or eligibility for a trust payment.", "pred_label": "__label__POS", "pred_score_pos": 0.9096056222915649} +{"content": "AM16: Heat pump installations for multi-unit residential buildings\nAM16: Heat pump installations for multi-unit residential buildings\nBy law, the UK is committed to reduce its greenhouse gas emissions to net zero by 2050. To achieve this goal our power grid has already begun to decarbonise and, to make the most of this, much of our building stock is destined to become ‘all-electric’ – as well as being cooled, lit and powered by electricity many of our buildings will also be heated with electricity.\nHeat pumps are the most efficient way to generate heat from electricity. Consequently, they have a crucial role to play in the transition to net zero, particularly in the residential sector where traditionally their market penetration has been low. AM16: Heat pump installations for multi-residential buildings provides guidance on the design and installation of heat pump systems for high-density developments, such as medium- and high-rise apartment buildings, care homes and student accommodation, including existing buildings. This guidance assumes that a heat pump has already been selected as the preferred primary heat source and principally covers installations within the UK market.\nThis Applications Manual deals predominantly with the design and optimisation of heat pump systems. It also covers the full life cycle, including installation, commissioning, operation, maintenance and decommissioning. Cost is always a key project driver – perhaps more so in residential construction than many others – and guidance on relative capital, energy and maintenance costs is included to help designers keep a weather eye on their client’s investment and the homeowners’ bills.\nA series of case studies are included detailing where heat pumps have been applied to new and existing multi-unit residential projects. In time, as heat pumps grow in popularity, so will the industry’s portfolio of success stories.\nHeat pumps will be a big part of our future as building services engineers and AM16 provides timely guidance and resource as we start down the road to an all-electric, zero carbon future.", "pred_label": "__label__POS", "pred_score_pos": 0.536636233329773} +{"content": "Scientists at UNIST have developed a ternary catalyst that converts greenhouse gases into hydrogen and carbon monoxide. The catalyst is composed of cobalt, nickel, and iron.\nThe dry reforming of methane (DRM) utilizes two ozone-harming substances, carbon dioxide (CO2) and methane (CH4), to create a syngas mixture of carbon monoxide (CO) and hydrogen (H2). Usually, nickel-based catalysts are the best options for the noble metals in the DRM response since they are cheap and dynamic. However, they become deactivated because of carbon deposition (coking), the accumulation of porous carbon materials, and the agglomeration of carbon particles.\nProfessor Guntae Kim in the School of Energy and Chemical Engineering at UNIST said,\n“This research, which focused on the development of a catalyst with enhanced activity and stability, will greatly contribute to the commercialization of the DRM technique.” “The catalyst’s cobalt-nickel-iron alloy nanoparticles allow the generation of a larger number of exsolved nanoparticles, separated at critical temperatures, to cause more enhanced catalytic activity than the conventional catalyst’s nickel monometallic and cobalt-nickel bimetallic particles.” “The activity and stability of a catalyst must be secured to produce syngas and hydrogen through DRM stably. The research team further noted that the exsolved catalyst exhibited exceptional stability, with continuous DRM operation for about 350 hours at a temperature above 750°C.” Journal Reference: Sangwook Joo, Kyeounghak Kim, Ohhun Kwon, et al., Enhancing Thermocatalytic Activities by Upshifting the d-Band Center of Exsolved Co-Ni-Fe Ternary Alloy Nanoparticles for the Dry Reforming of Methane. DOI: 10.1002/anie.202101335", "pred_label": "__label__POS", "pred_score_pos": 0.5745741128921509} +{"content": "As the COVID lockdown, while varying in some countries, continues globally, the availability of semiconductors have become scarce. This will inevitably reduce the manufacturing of processor chips and furthermore affecting the production of smartphones, PCs and other devices.\nIn order to oversee the situation, major tech giants such as Intel, AMD and Nvidia made a request, to the current President of the United States Joe Biden, to accelerate semiconductor productions through a letter written by the Semiconductor Industry Association. A part of the letter stated the following:\n“We therefore urge you to include in your recovery and infrastructure plan substantial funding for incentives for semiconductor manufacturing, in the form of grants and/or tax credits, and for basic and applied semiconductor research. We believe bold action is needed to address the challenges we face. The costs of inaction are high.”\nThe letter included signatures from the top semiconductor executives including Bob Swan from Intel, Lisa Su from AMD including other major companies such as the likes of IBM, Qualcomm etc. This letter was sent after President Biden had pledged to oversee the global semiconductor shortage.\nFurthermore, President Biden plans to sign an executive order to conduct a supply chain review for crucial semiconductor components.", "pred_label": "__label__POS", "pred_score_pos": 0.5035598278045654} +{"content": "Abstract\nBackground: Obesity (OB) and major depressive disorder (MDD) are chronic conditions associated with disease burden, and their comorbidity appears more common among women. Mechanisms linking these conditions may involve inflammatory and metabolic pathways. The goal of this study was to evaluate the impact of MDD on relationships between OB and cardiometabolic function, and sex differences therein. Materials and Methods: Adult offspring from the New England Family Studies (NEFS) were assessed at ages 39-50, including anthropometry, cardiometabolic profile assays, and metabolic syndrome. Individuals were grouped by body mass index (BMI) and MDD status: healthy weight with (n = 50) or without MDD (n = 95) and obese with (n = 79) or without MDD (n = 131). The interaction of (recurrent) MDD and BMI on cardiometabolic markers was tested using quantile regression models. Results: Participants with MDD exhibited significantly higher hemoglobin A1c (HbA1c) than those without MDD (5.60% vs. 5.35%, p < 0.05). Women with comorbid recurrent MDD and OB had higher HbA1c levels compared to obese women without MDD (5.75% vs. 5.44%, p < 0.05); an interaction between MDD and BMI status was not observed among men. Conclusions: We demonstrated sex differences in the interaction between BMI and recurrent MDD status on a primary biomarker for diabetes risk, suggesting a common metabolic pathway predisposing women to these comorbid conditions. Further investigation is needed to identify mechanisms that may lead to more effective, sex-dependent screening and therapies.\nKeywords diabetes epidemiology long-term weight mental health obesity ASJC Scopus subject areas Medicine(all)", "pred_label": "__label__POS", "pred_score_pos": 0.655469536781311} +{"content": "Laminar organization of neurons in cerebral cortex is critical for normal brain function. Two distinct cellular events guarantee the emergence of laminar organization– coordinated sequence of neuronal migration, and generation of radial glial cells that supports neurogenesis and neuronal migration. Our goal is to understand the cellular and molecular mechanisms underlying neuronal migration and layer formation in the mammalian cerebral cortex. Towards this goal, we are studying the following three related questions: 1. What are the signals that regulate the establishment, development and differentiation of radial glial cells, a key substrate for neuronal migration and a source of new neurons in cerebral cortex?2. What are the signals for neuronal migration that determine how neurons reach their appropriate positions in the developing cerebral cortex?3. What are the specific cell-cell adhesion related mechanisms that determine how neurons migrate and coalesce into distinct layers in the developing cerebral cortex?", "pred_label": "__label__POS", "pred_score_pos": 0.6225144863128662} +{"content": "Embracing OER as one of the most relevant assets within the Open Education movement has proved to be growing its adherence in LatAm. Although digital repositories are the channel with the largest capillarization potential for scholars and lifelong learners in the region, LatAm countries still face a great challenge when it comes to equally guaranteeing access to education. This presentation aims to showcase a case study that analyses the OA policies from 4 countries from the region and propose a sustainability model for OER digital repositories, including their copyright legislation factors.", "pred_label": "__label__POS", "pred_score_pos": 0.996434211730957} +{"content": "Abstrakt\nThe fuzzy front in product development is frequently mentioned as the most critical phase of the innovation process, and the five cases of successful design innovations here indicate that experiments and an experimental approach are generating positive outcomes. The experiments in the cases can be characterized as various forms of prototyping. Interestingly the prototyping and experiments took place in the very early phases of the innovation process, rather than later as often advised and interestingly experimentation in the cases here appears to be a vehicle for creating new options. Furthermore, the analysis demonstrates that prototyping can be considered as a punctuation device, as it offers those involved the option of opting out of ongoing processes, routines and engage in playful behavior by allowing for a freer experimentation with materials, processes, methods to challenge existing knowledge and explore potential solutions. In science, by contrast, experimentation generally is carried out to support, refute, or validate a hypothesis, in other words it seems to be associated with testing options rather than creating them.\nOriginalsprog Engelsk Tidsskrift CERN IdeaSquare Journal of Experimental Innovation Vol/bind 1 Udgave nummer 1 Sider (fra-til) 35-41 Antal sider 7 ISSN 2413-9505 DOI Status Udgivet - 2017 Emneord Fuzzy Front End Experiments Prototypes Punctuation Playfulness", "pred_label": "__label__POS", "pred_score_pos": 0.9748385548591614} +{"content": "The safety of goods and people is a key issue for energy operators. This imperative is based on the ability to prevent incidents,\nassess their risks and respond appropriately to incidents. when they occur. The first link in the chain is the implementation of the most effective gas leak detection technologies, and detection strategies tailored to each case. Related skills: gas quality.", "pred_label": "__label__POS", "pred_score_pos": 0.9879500269889832} +{"content": "Despite some recent rains, drought conditions are persisting.\nAccording to the US Army Corps of Engineers, winter releases from Gavins Point Dam will be 12,000 cubic feet per second as part of the overall water conservation measures.\nJohn Remus, chief of the U.S. Army Corps of Engineers’ Missouri River Basin Water Management Division, says last month the Corps reduced Gavins Point releases to 4,000 cfs as tributary flows downstream of the system increased. As the tributary runoff subsides, the Gavins Point releases will be adjusted to meet navigation flow targets.\nDespite localized heavy rainfall events throughout the basin during August, drought conditions expanded across the basin due to the exceptionally dry soils. August runoff in the upper Basin was 54% of average.\nAccording to the National Drought Mitigation Center, drought degradation is occurring across much of the upper Basin. Approximately 83% of the Missouri River basin is experiencing some form of abnormally dry conditions or drought. The seasonal drought outlook, which extends through the end of November, shows drought conditions persisting across most of the upper Basin.", "pred_label": "__label__POS", "pred_score_pos": 0.8026692867279053} +{"content": "No currently open grant opportunities\nIn November '13, the Israeli Ministry of Education announced its intention to introduce a new concept in Israel – public summer school for elementary schoolchildren. The main objective behind the idea was to create meaningful learning experiences for low-income Israeli children during July, thereby introducing a value-added “11th month” to the Israeli school year.\nSensing the urgency of this exciting new opportunity, two prominent family foundations – the Charles and Lynn Schusterman Family Foundation and The Steinhardt Family Foundation in Israel – decided to take action. These insightful foundations recognized the increasing importance of English for Israeli students and professionals, on the one hand, and the growing need for an authentic educational service project in Israel for young, international Jewishly-connected educators, on the other. The two foundations partnered with Israel's Ministry of Education to create a unique new program on Israel’s educational landscape – TALMA.\nUnder the guiding belief that English proficiency is essential to unlocking future opportunities for Israel's low-income youth, TALMA's social justice driven international educators devote their summer to volunteer-teaching with TALMA. In return, participating educators - TALMA Fellows - receive an all-expenses-paid summer of top-notch professional development and networking opportunities in Israel, an inspiring location that serves as the ideal backdrop for learning how to lead and create social change within complex systems and environments.\nTALMA has impacted more than 120 schools, 500+ educators & 10,000+ students spanning all of Israel's diverse populations. This giving circle is to ensure the continuation & expansion of TALMA's impact and community.\nNo currently open grant opportunities No grants awarded yet\nOur Jewish Giving Circle Incubator will help you bring your giving circle to life. Whether you're 23 or 73, interested in social justice or Jewish innovation, and ready to give $50 or $10,000, we want you to join the Incubator. Apply today!\nApplications are open until July 31st.Apply Now", "pred_label": "__label__POS", "pred_score_pos": 0.6691887378692627} +{"content": "Pennsylvania voters of every political party are expressing their support for public health policies that better protect us from pollution. This includes emissions released through fracking by the shale gas industry, which has flooded into Western Pennsylvania over the last decade.\nThe Ohio River Valley Institute’s recent opinion poll reveals that 78% of Pennsylvania voters are concerned about how pollution affects their community’s health. At........", "pred_label": "__label__POS", "pred_score_pos": 0.8980889916419983} +{"content": "Abstract Date Presented 4/20/2018\nFeeding challenges are prevalent in children with autism spectrum disorder (ASD), often disrupting family mealtimes. Limited research has examined tools families incorporate to support mealtime engagement. This study explored the tools (e.g., toys, books) and their purpose that families used during mealtimes with children with ASD.\nPrimary Author and Speaker: Jessica Muesbeck Additional Authors and Speakers: Shannon Kant, Brittany St. John, and Karla Ausderau", "pred_label": "__label__POS", "pred_score_pos": 0.9987300038337708} +{"content": "Abstract\nThe aims of this study were to examine the effect of old age on the pharmacokinetics of morphine and morphine-6β-glucuronide (M6G) and their relationships to antinociceptive activity. Morphine (21.0 μmol/kg) or M6G (21.7 μmol/kg) were administered s.c, to young adult and aged male Hooded-Wistar rats. Antinociceptive effect was measured by the tail-flick method at various times up to 2.5 h or 6.5 h after morphine or M6G administration, respectively, and concentrations of morphine, morphine-3β-glucuronide (M3G) and M6G in plasma and brain were determined by HPLC. Creatinine clearance was significantly lower by 33% or 21% in aged compared to young adult rats receiving morphine or M6G, respectively. After morphine administration, the areas under the (i) antinociceptive effect-time curve, (ii) plasma morphine concentration-time curve, and (iii) brain morphine concentration-time curve were not different between young adult and aged rats. However, the AUC for plasma M3G was five-fold higher in the aged relative to young adult rats, which could not be accounted for by only a 33% lower creatinine clearance. M6G was not detected in any plasma or brain sample from rats administered morphine and no M3G was detected in brain. For M6G administration, the areas under the (i) antinociceptive effect-time curve, and (ii) plasma M6G concentration-time curve were 1.8- and 1.6-fold higher in aged compared to young adult rats, respectively. Concentrations of M6G in brain were below the limit of quantification. No morphine or M3G was detected in any of the plasma or brain samples of rats administered M6G. The results demonstrate no change in morphine antinociception and pharmacokinetics with age, and suggest that blood-brain barrier permeability and receptor sensitivity to morphine are not altered in aged rats. Accumulation of M3G in plasma of aged rats is probably due to diminished renal clearance of M3G in addition to a reduction in the biliary excretion of M3G. The heightened sensitivity of the aged rats to M6G is probably due to the observed altered kinetics of M6G rather than a pharmacodynamic change.\nKeywords Age Morphine Morphine-6β-glucuronide Pharmacodynamics Pharmacokinetics Rat", "pred_label": "__label__POS", "pred_score_pos": 0.5739722847938538} +{"content": "The Molecular Analysis for Precision Oncology Congress 2022 will take place in Amsterdam, Netherlands, from 14 to 16 October.\nMAP is the leading global meeting dedicated to precision oncology, defined as molecular profiling of tumours to identify targetable alterations. This oncology field is fast evolving and has now entered the mainstream of clinical practice.\nAt MAP 2022, international key opinion leaders will explain how to use genomic data for treating cancer patients, matching such data to a specific drug or therapy, based on the genetic drivers detected in the patients’ tumours, and they will debate about the future challenges in precision oncology.\nThe MAP Congress is the result of a solid partnership among Cancer Research UK (CRUK), the European Society for Medical Oncology (ESMO) and Unicancer, all committed to offering the best care to people with cancer worldwide, through oncology education and research.\nWe look forward to seeing you at MAP 2022 in Amsterdam!\nVenue\nThe Congress will take place at the Amsterdam Conference Centre Beurs van Berlage, Damrak 243, Amsterdam\nOrganisation\nMAP Congress Team\nc/o ESMO Head Office Via Ginevra 4 6900 Lugano Switzerland map@esmo.org", "pred_label": "__label__POS", "pred_score_pos": 0.7227916717529297} +{"content": "To print this article, all you need is to be registered or login on Mondaq.com. I. INTRODUCTION\nSimply put, a ‘\nPonzi scheme‘ is a scam\ninvestment purposed at cheating investors. It involves persuading the public to invest in fraudulent, seemingly lucrative, schemes. With nearly no real income, these thrive on a consistent progression of new money to survive. When it reaches a point of no new investors, or the existing one’s cash out, the scheme collapses. On the face of it, its irrationality is evident. Yet, the threat it has posed in domestic society is undeniable.\nResorting to investment schemes that offer high returns is not\nuncommon. Undoubtedly, extraordinarily high returns to the tune of 100-120% are red flags. But this continues to remain a deeply ingrained socio-economic problem. 1\nCharles Ponzi in the early 1920s notably duped thousands of New\nEngland residents by…", "pred_label": "__label__POS", "pred_score_pos": 0.7579575777053833} +{"content": "At birth, synaptic sites in developing rodent muscles are innervated by numerous motor axons. During subsequent weeks, this multiple innervation disappears as one terminal strengthens, and all the others are eliminated. Experimental perturbations that alter neuromuscular activity affect the rate of synaptic refinement, with more activity accelerating the time to single innervation and neuromuscular blockade retarding it. However, it remains unclear whether patterns of muscle use (driven by endogenous neuronal activity) contribute to the rate of synapse elimination. For this reason we examined the timing of supernumerary nerve terminal elimination at synapses in extraocular muscles (EOMs), a specialized set of muscles controlling eye movements. On the basis of their exceptionally high patterns of activity, we hypothesized that synaptic refinement would be greatly accelerated at these synapses. We found, however, that rates of synaptic refinement were only modestly accelerated in rectus and oblique EOMs compared with synapses in somite-derived skeletal muscle. In contrast to these results, we observed a dramatic delay in the elimination of supernumerary nerve terminals from synapses in the levator palpebrae superioris (LPS) muscle, a specialized EOM that initiates and maintains eyelid elevation. In mice, natural eye opening occurs at the end of the second postnatal week of development. Thus, although synapse elimination is occurring in most EOMs and somite-derived skeletal muscles, it appears to be dramatically delayed in a set of specialized eyelid muscles that remain immobile during early postnatal development.", "pred_label": "__label__POS", "pred_score_pos": 0.8520498871803284} +{"content": "case study corporate credit analysisgo to sitehttps://abt.edu/bestsellers/centro-medico-polispecialistico-villanova-di-guidonia/22/seeessays on how to stop bullying in schoolgo to linkhelp writing essaypatatas al cialisfluoxetine hcl 20 mg pricewatchsource urlpiled higher and deeper thesis writingfollow linkclick hereseealternative viewpoints essaycialis danmarkhttps://thembl.org/masters/case-study-security-risk-assessment/60/argumentative essay on medicinebenefits of a positive organizational culture essayviagra meno costosohttps://medpsychmd.com/nurse/viagra-irregular-heartbeat/63/see url200mg celebrex medicine vioxxfollowhttps://campuschildcare-old.wm.edu/thinking/essay-about-love-poetry/10/source urlhttps://abt.edu/bestsellers/is-it-dangerous-to-take-cialis/22/get linkdescriptive essay on hiroshimahttps://eagfwc.org/men/viagra-super-force-reviews/100/https://chanelmovingforward.com/stories/top-writing-services/51/ BASSETERRE, St. Kitts, March 26, 2018 (Press Unit in the Office of the Prime Minister) – St. Kitts and Nevis’ Prime Minister, Dr. the Honourable Timothy Harris, has outlined various concerns the Federation has with respect to the recent listing of the twin island Federation as a non-cooperative tax jurisdiction by the European Union.\nEarlier today (Monday, March 26), Prime Minister Harris expressed concerns of fairness, deadlines and economical impact during a meeting with a high-level European Union mission, led by Director-General for International Cooperation and Development in the European Commission, Mr. Stefano Manservisi.\nDuring the frank discussions, which were also attended by Financial Secretary in the Government of St. Kitts and Nevis, Mrs. Hilary Hazel and Cabinet Secretary, Mrs. Josephine Huggins, Dr. Harris said that his Government strongly rejects St. Kitts and Nevis’ inclusion to the list of non-cooperative tax jurisdictions, noting that “the process in our view is somewhat a bit unfair; unfair to small states like St. Kitts and Nevis in that we hardly had enough time to deal with these issues; and the kind of guidelines, which the EU provides is highly inadequate.”\nPrime Minister Harris stressed that the matter of blacklisting countries is one that should not be taken lightly. He added, “Every country in our view should be given real opportunities and reasonable timeframe within which to respond to these requirements.”\nFinancial Secretary, Mrs. Hilary Hazel, further noted that the language as it relates to the requirements outlined by the EU is often difficult to interpret and understand, and as a result creates a stumbling block.\nThe financial secretary also agreed with the summation by Prime Minister Harris that these decisions to list countries like St. Kitts and Nevis, which remain committed to international standards on transparency and exchange of information for tax purposes, pose significant challenges for the country’s economy.\n“You mentioned that we had a fairly good showing relative to the OECS group in terms of the prospects for growth – financial services is one of those pillars that make this possible. And so to remove that pillar or to disrupt it in a significant way leaves us in a state where we would really have to do some serious reconfiguration of the economic structure of the country,” Mrs. Hazel stated.\nMr. Manservisi acknowledged the concerns expressed by Prime Minister Harris and the financial secretary and called for continued dialogue between small island states like St. Kitts and Nevis, the European Union and its partners.\nIn the case of St Kitts and Nevis, the only area of concern from the EU is in respect of fair taxation. It stated that “a jurisdiction should have no preferential tax measures that could be regarded as harmful and a jurisdiction should not facilitate offshore structures or arrangements aimed at attracting profits which do not reflect real economic activity in the jurisdiction.”\nFinancial Secretary Hazel stated, in a national address on March 13, that St. Kitts and Nevis is a committed and fully cooperative jurisdiction in the context of international tax transparency.\nThis, she said, is evident by the “Largely Compliant rating by the Organization for Economic Co-operation and Development (OECD). Further, Saint Kitts and Nevis has continued to expand its exchange of information network and is a signatory to the Multilateral Convention on Mutual Administrative Assistance for Tax Matters.”", "pred_label": "__label__POS", "pred_score_pos": 0.6573039293289185} +{"content": "After a loved one passes, you'll have to deal with their estate. In the best cases, this process goes smoothly, but estate disputes do occur. The Law Office of John Lemieux in Portland, ME can help with mediation or representation in an estate dispute. Attorney Lemieux answers most calls, texts and emails within a day and will provide assistance ASAP.\nYou can reach him at 207-347-3198.\nIf you've lost a loved one, the last thing you want to think about is a legal dispute. However, disputes are sometimes unavoidable. You may want to open an estate dispute if:\nYou suspect a will has been tampered with You have an ongoing conflict with an executor You are concerned about a sudden incapacitation\nIf someone experiences a sudden or unexpected incapacitation or disability, they may not have a will or trust in place. In this situation, it's best to find an estate dispute lawyer to help you. Retain attorney Lemieux for sound legal counsel.", "pred_label": "__label__POS", "pred_score_pos": 0.529180645942688} +{"content": "The self-employed income support scheme (SEISS) grant, introduced by the government to help businesses through the coronavirus pandemic, is open for applications again.\nThis grant can award businesses up to £7,500.\nHowever, businesses may have to submit two turnover figures to successfully apply.\nHow do you apply?\nHMRC has either emailed or sent a letter to every self-employed taxpayer who may be able to apply for the grant. This gives the business a personal start date from which they can apply. Applying before the start date will invalidate the application and it will not be processed.\nDifferent start dates have been given to businesses to reduce the number of crashes the government website experiences.\nThe first day of application was the 29\nth July and will remain open until 30 September 2021. What makes a business eligible?\nHMRC has already conducted a basic check for eligibility within the 2019/20 tax return, submitted by 2 March 2021.\nWithin the tax return, the taxpayer must have made a declaration that they intend to keep trading in 2021/22. They must also have declared profits will sustain a ‘significant reduction’ between 1 May 2021 and 30 September 2021 due to the pandemic.\nWhile HMRC have not elaborated on the meaning of ‘significant’, the taxpayer is only required provide a forecast for profits in the period ending 30 September 2021. The forecast provided will not be re-examined after September 30\nth.\nHowever, businesses will need to keep any evidence of why they believed profits were going to be negatively impacted due to covid-19.\nDo not worry if you were too late to apply for the SEISS-4 grant. If you were eligible, you will still be able to apply for the SEISS-5 grant, so long as the other conditions are fulfilled.\nWhat turnover data do you need to submit?\nMost taxpayers applying will now need to submit two different turnover figures. These figures will be the 12-month turnover between April 2020/21, and, in most cases, the turnover figure for April 2019/20 as a reference point.\nNew businesses who started trading in 2019/20 and did not have a self-employed trade between the years 2016/17 to 2018/19, do not have to provide any turnover figures. HMRC already has the figure for 2019/20 via their tax return.\nThese businesses will receive the higher-level grant, awarding them 80% average trading profits across 3 months.\nSome argue that turnover does not accurately measure the ‘significant losses’ incurred to the business due to the pandemic. Other factors like deferred loan repayments and staff redundancies might mean the business is worse off despite a stable turnover.\n[Article written 8th Aug, 2021]", "pred_label": "__label__POS", "pred_score_pos": 0.6690126657485962} +{"content": "Big Development in Electronic IDs Market as Researchers Create a New Method to Identify Counterfeit Electronic Devices\nPosted On September 21, 2021\nThe interconnection between digital electronics, wireless technologies, and micromechanical electronic has grown over the decade. However, with the growing ease also comes the question of security. The Internet of Things is exceptionally vulnerable to forgeries and external tampering, leading to complete telecommunication networks failure. In 2017, counterfeit devices sold from pharmaceuticals to electronics comprised $1.2 Trillion (approx.) worldwide. As a result, improved security measures or solutions that can assist consumers in distinguishing between counterfeit and genuine products are urgently needed.\nResearchers have unveiled a new method that could help avert counterfeit computer chips and other technologies from saturating the market. The approach demonstrated can authenticate products prior to their shipment from the factors electronically. The method has the potential to be a massive contribution to the Electronic Ids Market as it facilitates unique identifications of components in a way that is unalterable, inexpensive, and secure.\nTo develop the method, the team employed a popular technique referred to as ‘doping.’ The process involves the implantation of tiny clusters of “foreign” atoms (differentiated from the elements present in the device) beneath the surface. The atoms so implanted work towards altering the electrical properties of the device’s topmost layer without causing any harm. Thus, a unique label is created as a result that can be read-only through an electrical scanner.\nDoping as a tool for creating electronic tags for the device is not a particularly novel idea. However, the present technique gets the edge as it uses the sharp tip of an AFM (Atomic Force Microscope) to probe the implant atoms. This makes the procedure cost-efficient and straightforward while also reducing the need for sophisticated equipment than the techniques that employ lasers or beams of ions. Further, the process is also comparatively less damaging.\nThe team narrated that a sticker is embedded in every device wherein each is electronic and unique due to the different amounts and forms of dopant present in atoms. Every dopant-modified lattice has novel impedance according to type and amount of dopant. This results in the production of a lattice that can work as a differentiated electronic label like a nanometer-scale version of a QR code. Whenever a beam of radio waves from the scanner is directed towards the device, the electrically altered lattice will respond by producing a unique radiofrequency matching their impedance. In this manner, counterfeit devices can be easily recognized as they would never respond to the scanner like the original ones.", "pred_label": "__label__POS", "pred_score_pos": 0.7031254768371582} +{"content": "Removalists make it easy and convenient to move your home or office. An ideal move involves some collaboration between the client and removalist. The article below discusses a few disclosures that you should make when hiring a removalist. Hopefully, it will ensure you have an easy time when dealing with your removalist.\n1. The Location Of Your Home And New Premises\nYou must give intricate details about the location of your current and new premises. This enables the removalist to know how far they will have to transport your items. Besides, they will know when to schedule the move if the roads are impassable during certain times of the day. Remember to inform the removalist if you live in a multi-storey building. Remember, they might require special equipment to move your items down a narrow staircase.\n2. The Items You Intend To Move\nThe removalist must know the items that you intend to move. This ensures that they come with the right truck and equipment. In some cases, the removalist will visit your home for a physical inspection. If this is not possible, send the removalist photos. This ensures adequate preparation. For example, the removalist could ask you to defrost the refrigerator a few hours before they arrive. If you have sensitive electronics, the removalist will ask if you have their original packaging material. If not, they will look for special boxes, removal blankets and bubble wrap.\n3. Your Valuables\nMany people will forget to inform the removalist about their valuables. However, they need this information since the presence of valuables will significantly affect how the removalist plans the move. For example, you might need a secure transport option to move expensive paintings, rare artefacts and jewellery.\n4. Moving Time\nWhen do you intend to move? Most removalists will try and move within your schedule. However, different factors could compel the removalist to adjust the removal time. For example, if you are moving interstate, the removalist could ask you to move late at night since some states restrict heavy haulage during the day.\n5. Removal Budget\nAsk the removalist for a quote and check if it falls within your budget. If the quote is too high, ask the professional to initiate some cost-saving measures. For example, you could lease the moving cartons instead of purchasing them. Alternatively, you could ask the removalist to use a backloading service.\nWhen hiring a removalist, disclose the location of your premises, what you plan to move, your valuables and your budget. Contact a company that offers furniture removal solutions to learn more.\nShare", "pred_label": "__label__POS", "pred_score_pos": 0.9951716065406799} +{"content": "The\nWyoming standard residential lease agreement is used to establish a rental arrangement between a landlord and tenant in a legal document signed by both parties. Once completed, the lease will relay all the terms and conditions of the agreement, including the rental price, lease term, tenant’s responsibilities, and landlord’s rules and right to access.\nThe document will also list any additional fees, payments, and deposits that the tenant will be required to make, as well as any utilities, appliances, and furnishings that are included in the rental. The document becomes legally binding when both parties have signed, and it remains effective for the duration of its terms or until the contract is breached.\nHandbook (Guide) – Landlord-Tenant Handbook\nContents Maximum – Not mentioned in state statutes. Returning (§ 1-21-1208(a)) – Thirty (30) days from lease termination date or fifteen (15) days from the date that the landlord receives the tenant’s new address.\nState law does not specify when rent must be paid or if the tenant is allowed a grace period before late fees can be charged for past due rent. Therefore, rent is due as stated in the lease and the tenant will not receive a grace period unless the written agreement provides for one.\nUsed to disclose the use of lead paint in the rental unit (required if the dwelling was built before 1978).\nIf any portion of the tenant’s security deposit is non-refundable, the tenant must be informed via written notice at the time the landlord or designated agent is receiving the deposit.", "pred_label": "__label__POS", "pred_score_pos": 0.9167096018791199} +{"content": "Employee experience has risen to the top of many organisations’ agendas as they strive to differentiate themselves, and the ongoing pandemic has only amplified its importance.\nThis report set out to understand what factors are driving employee experience at various organisations, what strategies are being implemented to improve it, and what’s preventing them from reaching their goals.\nThe report is filled with eye-opening findings, including this significant response:\nRequest Free!", "pred_label": "__label__POS", "pred_score_pos": 1.0000094175338745} +{"content": "Object\nEmerging research in evoked broadband electrocorticographic (ECoG) measurement from the cortical surface suggests that it might cleanly delineate the functional organization of cortex. The authors sought to demonstrate whether this could be done in a same-session, online manner to identify receptive and expressive language areas.\nMethods\nThe authors assessed the efficacy of simple integration of “χ-band” (76–200 Hz) change in the ECoG signal by implementing a simple band-pass filter to estimate broadband spectral change. Following a brief (less than 10-second) period to characterize baseline activity, χ-band activity was integrated while 7 epileptic patients with implanted ECoG electrodes performed a verb-generation task.\nResults\nWhile the patients were performing verb-generation or noun-reading tasks, cortical activation was consistently identified in primary mouth motor area, superior temporal gyrus, and Broca and Wernicke association areas. Maps were robust after a mean time of 47seconds (using an “activation overlap” measure). Correlation with electrocortical stimulation was not complete and was stronger for noun reading than verb generation.\nConclusions\nBroadband ECoG changes can be captured online to identify eloquent cortex. This demonstrates the existence of a powerful new tool for functional mapping in the operative and chronic implant setting.", "pred_label": "__label__POS", "pred_score_pos": 0.6989039182662964} +{"content": "NEW YORK (GenomeWeb) – Noninvasive prenatal testing has limited clinical utility for subchromosomal abnormalities, according to a team of UK-based researchers.\nAs the popularity of NIPT tests for detecting fetal aneuploidies like trisomies 21, 18, and 13 has risen, commercial providers have moved to expand their offerings to include recurrent microdeletions and microduplications.\nBut as University College London's Lyn Chitty and her colleagues reported in the\nAmerican Journal of Human Genetics today, a calling pipeline they developed to detect subchromosomal rearrangements could not reliably detect microdeletions or microduplications even as it uncovered most large chromosomal rearrangements.\nWhile increasing sequencing depth could improve detection, it would also increase the false positive rate, the researchers noted.\n\"[T]o be effective, NIPT must be able to detect chromosomal rearrangements across the whole genome for a very low false-positive rate,\" Chitty and her colleagues wrote in their paper. \"Because standard NIPT can only detect the majority of larger chromosomal rearrangements and requires knowledge of fetal fraction, we consider that it is not yet ready for routine clinical implementation. \"\nA study appearing in the\nProceedings of the National Academy of Sciences last month similarly reported that while NIPT approaches could detect subchromosomal deletions and duplications, they would likely need a higher fetal DNA percentage or depth of coverage than conventional aneuploidy testing, and would have a higher false positive rate.\nIn this study, Chitty and her colleagues used 12-plex sequencing to detect chromosomal rearrangement in 20 of the 31 cell-free DNA samples obtained from maternal plasma they examined. All the samples, which were collected as part of the UK Rapid Accurate Prenatal Noninvasive Diagnosis project, contained known unbalanced chromosomal rearrangements.\nFor 15 of the 18 samples with CNVs larger than 6 megabases, the researchers were able to detect at least one abnormality, a sensitivity of 83 percent.\nHowever, the researchers were only able to detect CNVs smaller than 6 megabases in five samples, and three of those had duplications for which the mother was also a carrier. For the 10 other samples with small CNVs, only two were correctly identified, a sensitivity of 20 percent.\nThe researchers also tested their pipeline on a set of 534 samples with no known chromosomal abnormalities. After filtering, they had false calls in two samples, yielding a specificity of 99.6 percent.\nDeeper sequencing — to a read depth of 120 million reads — identified fetal CNVs that were missed at the shallower sequencing depth in nine of the 11 samples. For instance, they noted that a 22q11.2 deletion in one fetus could be detected once the sequencing depth reached 32 million reads.\nOverall, deeper sequencing increased the test sensitivity to 94 percent for CNVs larger than 6 megabases and to 93 percent for CNVs larger than 1.5 megabases.\nDeeper sequencing also failed to reveal CNVs that had been previously identified. This discrepancy, the researchers noted, is likely due to fetal fraction. In one case, a male fetus was reported to have a 3-megabase deletion in 22q11.2, but using the reads mapped to the Y chromosome, the researchers estimated the fetal fraction to be only 2.5 percent.\nChitty and her colleagues estimated their power to detect CNVs of different sizes at a range of fetal fractions. While they noted that their calculations are specific to their laboratory, they found that the sensitivity of the test didn't improve substantially with increased sequencing depth if the fetal fraction fell below 5 percent.\nAt the same time, they reported that CNVs as small as 1 megabase could be detected with 38 million reads if the fetal fraction was greater than 20 percent.\nThe cost of increasing the sequencing depth, they noted, would be high, and would lead to an increased false positive rate.\n\"Given that a significant benefit of using NIPT to screen for aneuploidy is the increased safety secondary to the reduced need for invasive testing, extending NIPT to include screening for subchromosomal rearrangements stands to reverse some of this benefit whilst not offering comprehensive detection of pathogenic rearrangements,\" Chitty and her colleagues wrote.", "pred_label": "__label__POS", "pred_score_pos": 0.6012574434280396} +{"content": "NEW YORK (GenomeWeb) – A research team from China and Korea has characterized the mutations found in secondary glioblastoma (GBM), uncovering potentially-targetable MET alterations in cases with more rampant disease progression and poorer outcomes.\nInvestigators at Capital Medical University, Hong Kong University, and elsewhere used whole-genome, exome, and/or targeted DNA sequencing to assess samples from 145 East Asian individuals with secondary GBM — a recurrent form of the disease that arose after standard treatment with the non-selective, DNA-damaging chemotherapy temozolomide (TMZ).\nTogether with RNA sequence data for a subset of the cases, their genomic data revealed hypermutated secondary GBM cases and cases marked by recurrent TP53 mutations, MET amplifications, fusions involving the PTPRZ1-MET genes, and exon skipping events affecting exon 14 of MET.\nIn a paper published online today in\nCell, the team noted that there appeared to be potential for targeting the MET exon 14 skipping and PTPRZ1-MET fusions — which often co-occur — using a MET kinase inhibitor known as PLB-1001. That compound produced promising results in cell line or tumor xenografts experiments, as well as in a phase I clinical trial which included 18 secondary GBM or glioma patients with exon 14-skipped MET or PTPRZ1-MET fusions, the group reported.\n\"Given the lack of therapeutic options for recurrent tumor[s] under TMZ treatment, our study has provided a promising therapeutic strategy of PLB-1001 mono- and combinatorial treatments with TMZ chemotherapy for patients with MET alterations,\" the authors wrote.\nThe researchers brought together samples from 188 secondary GBM patients enrolled through efforts such as the Chinese Glioma Genome Atlas project or at the Samsung Medical Center. Using Illumina instruments, they sequenced genomes, exomes, or a panel of 272 Agilent SureSelect-captured gene sequences in matched tumor and normal samples from 145 cases.\nAlong with somatic alterations identified from these sequences, the team did RNA sequencing in 78 of the secondary GBM samples to get a closer look at the gene fusions and MET exon 14 skipping events. The latter alterations were present in 14 percent of the cases, and a comparison with available primary GBM and low-grade glioma (LGG) data pointed to particularly low overall survival rates for secondary GBM cases with METex14.\nThe researchers examined the MET changes in more detail in secondary GBM, primary GBM, and LGG. They found that METex14 alterations — linked to enhanced MET/STAT3 signaling, a boost tumor growth, and tumor gene expression and microenvironment differences — often occurred in conjunction with the PTPRZ1-MET fusions.\nBased on the growth inhibition they saw in cell lines treated with several MET inhibitors, the researchers pursued a phase I clinical trial using PLB-1001, which has binding abilities that suggested it should cross the blood brain barrier to get into the brain. In that dose escalation study, which involved nine secondary GBM and nine advanced glioma patients with METex14 or PTPRZ1-MET fusions in their tumors, they reported a partial response in two patients with secondary GBM.\nThe median response duration spanned more than 62 days, the team noted, while the median progression-free survival reached 80 days during the monotherapy trial.\n\"Encouragingly, PLB-1001 achieves partial response in at least two advanced [secondary GBM] patients with rarely significant side effects,\" the authors wrote, \"underscoring the clinical potential for precisely treating gliomas using this therapy.\"", "pred_label": "__label__POS", "pred_score_pos": 0.7638543844223022} +{"content": "This guideline covers exercise referral schemes for people aged 19 and older, in particular, those who are inactive or sedentary. The aim is to encourage people to be physically active.\nSearch results 481 results\nThis guideline covers lifestyle weight management services for children and young people aged under 18 who are overweight or obese. It advises how to deliver effective weight management programmes that support children and young people to change their lifestyle and manage their weight.\nThis guideline covers helping people to stop smoking in acute, maternity and mental health services. It promotes smokefree policies and services and recommends effective ways to help people stop smoking or to abstain from smoking while using or working in secondary care settings.\nThis guideline covers changing health-damaging behaviours among people aged 16 and over using interventions such as goals and planning, feedback and monitoring, and social support. It aims to help tackle a range of behaviours including alcohol misuse, poor eating patterns, lack of physical activity, unsafe sexual behaviour and smoking.\nThis guideline covers the link between body mass index (BMI) and waist circumference and the risk of disease among adults from black, Asian and other minority ethnic groups in the UK. The aim was to determine whether lower cut-off points should be used for these groups as a trigger for lifestyle interventions to prevent conditions such as diabetes, myocardial infarction or stroke.\nThis guideline covers improving oral health by developing and implementing a strategy that meets the needs of people in the local community. It aims to promote and protect people’s oral health by improving their diet and oral hygiene, and by encouraging them to visit the dentist regularly.\nThis guideline covers providing brief advice on physical activity to adults in primary care. It aims to improve health and wellbeing by raising awareness of the importance of physical activity and encouraging people to increase or maintain their activity level.\nThis guideline covers reducing harm from smoking. It aims to help people, particularly those who are highly dependent on nicotine, who:\nThis guideline covers good practice for developing, authorising, using and updating patient group directions. It also offers advice on deciding whether a patient group direction is needed.\nThis guideline covers a set of principles that can be used to help people change their behaviour. The aim is for practitioners to use these principles to encourage people to adopt a healthier lifestyle by, for example, stopping smoking, adopting a healthy diet and being more physically active.\nThis guideline covers diagnosing and managing gastro-oesophageal reflux disease in children and young people (under 18s). It aims to raise awareness of symptoms that need investigating and treating, and to reassure parents and carers that regurgitation is common in infants under 1 year.\nThis guideline covers how to identify adults at high risk of type 2 diabetes. It aims to remind practitioners that age is no barrier to being at high risk of, or developing, the condition. It also aims to help them provide those at high risk with an effective and appropriate intensive lifestyle-change programme to prevent or delay the onset of type 2 diabetes. The recommendations in this guideline can be used alongside the NHS Health Check programme .\nThis guideline covers people living in England with ancestral links to Bangladesh, India, Nepal, Pakistan or Sri Lanka who use traditional South Asian varieties of smokeless tobacco. The aim is to help them stop using tobacco that is placed in the mouth or nose (but not burned). It does not include oral snuff products that are sucked.\nThis guideline covers supporting the social and emotional wellbeing of vulnerable children under 5 through home visiting, childcare and early education. It aims to optimise care for young children who need extra support because they have or are at risk of social or emotional problems.\nThis guideline covers how local communities, with support from local organisations and networks, can help prevent people from becoming overweight or obese or help them lose weight. It aims to support sustainable and community-wide action to achieve this.\nThis guideline covers raising awareness of and testing for hepatitis B and C infection. It aims to ensure that people at increased risk of hepatitis B and C infection are tested.\nThis guideline covers home safety assessments, supplying and installing safety equipment and providing education and advice. It aims to prevent unintentional injuries among all children and young people aged under 15 but, in particular, those living in disadvantaged circumstances.\nThis guideline covers road speed limits, 20mph zones and engineering measures to reduce speed or make routes safer.\nThis guideline covers preventing type 2 diabetes in adult populations and communities who are at high risk. It aims to promote a healthy diet and physical activity at community and population level, and recommends how to tailor services for people in ethnic communities and other groups who are particularly at risk of type 2 diabetes.\nThis guideline covers encouraging people to increase the amount they walk or cycle for travel or recreation purposes.\nThis quality improvement guide was produced by NICE, in partnership with the Health Protection Agency (HPA). Its aim is twofold: to reduce the risk of harm from healthcare-associated infections for patients, staff and visitors; and to reduce the costs associated with preventable infection.\nThis guideline covers new buildings and communal outdoor areas. The aim is to ensure there are enough shady areas to protect people from overexposure to the sun.\nThis guideline sets out an antimicrobial prescribing strategy for secondary bacterial infection of eczema and covers infection of other common skin conditions. It aims to optimise antibiotic use and reduce antibiotic resistance. The recommendations are for adults, young people and children aged 72 hours and over. They do not cover diagnosis.\nThis guideline covers mental health rehabilitation for adults with complex psychosis. It aims to ensure people can have rehabilitation when they need it and promotes a positive approach to long-term recovery. It includes recommendations on organising rehabilitation services, assessment and care planning, delivering programmes and interventions, and meeting people’s physical healthcare needs.\nThis guideline sets out an antimicrobial prescribing strategy for insect and spider bites and stings in adults, young people and children aged 72 hours and over, including those that occurred while travelling outside the UK. It aims to limit antibiotic use and reduce antibiotic resistance.\nThis guideline covers interventions that use a digital or mobile platform to help people eat more healthily, become more active, stop smoking, reduce their alcohol intake or practise safer sex. The interventions include those delivered by text message, apps, wearable devices or the internet. The guideline only includes those that are delivered by the technology itself and not by healthcare professionals using technology to deliver interventions.\nThis guideline covers the diagnosis and management of type 1 and type 2 diabetes in children and young people aged under 18. The guideline recommends how to support children and young people and their families and carers to maintain tight control of blood glucose to reduce the long-term risks associated with diabetes.\nThis guideline sets out an antimicrobial prescribing strategy for human and animal bites (excluding insect bites) in adults, young people and children aged 72 hours and over. It aims to optimise antibiotic use and reduce antibiotic resistance.\nThis guideline covers care before, during and after a planned knee, hip or shoulder replacement. It includes recommendations to ensure that people are given full information about their options for surgery, including anaesthesia. It offers advice for healthcare professionals on surgical procedures and ensuring safety during operations. It also offers guidance on providing support and rehabilitation before and after surgery.\nThis guideline covers diagnosing and managing venous thromboembolic diseases in adults. It aims to support rapid diagnosis and effective treatment for people who develop deep vein thrombosis (DVT) or pulmonary embolism (PE). It also covers testing for conditions that can make a DVT or PE more likely, such as thrombophilia (a blood clotting disorder) and cancer.\nThis guideline covers integrated diagnostic reporting for diagnosing haematological cancer in adults, young people and children. It also covers staffing, facilities (levels of care) and multidisciplinary teams needed for adults and young people. It aims to improve care for people with suspected or diagnosed cancer by promoting best practice on the organisation of haematological cancer services.\nThis guideline covers how to identify the adults, young people and children with non-alcoholic fatty liver disease (NAFLD) who have advanced liver fibrosis and are most at risk of further complications. It outlines the lifestyle changes and pharmacological treatments that can manage NAFLD and advanced liver fibrosis.\nThis guideline covers diagnosing and managing non-Hodgkin's lymphoma in people aged 16 years and over. It aims to improve care for people with non-Hodgkin's lymphoma by promoting the best tests for diagnosis and staging and the most effective treatments for 6 of the subtypes. Tests and treatments covered include excision biopsy, radiotherapy, immunochemotherapy and stem cell transplantation.\nThis guideline covers approaches to promoting social and emotional wellbeing in children aged 4 to 11 years in primary education. It includes planning and delivering programmes and activities to help children develop social and emotional skills and wellbeing. It also covers identifying signs of anxiety or social and emotional problems in children and how to address them.\nThis guideline covers how to encourage employees to be physically active. The aim is to increase the working population’s physical activity levels.\nThis guideline covers routine preoperative tests for people aged over 16 who are having elective surgery. It aims to reduce unnecessary testing by advising which tests to offer people before minor, intermediate and major or complex surgery, taking into account specific comorbidities (cardiovascular, renal and respiratory conditions and diabetes and obesity). It does not cover pregnant women or people having cardiothoracic procedures or neurosurgery.\nThis guideline covers the organisation and provision of major trauma services in pre-hospital and hospital settings, including ambulance services, emergency departments, major trauma centres and trauma units. It aims to reduce deaths and disabilities in people with serious injuries by providing a systematic approach to the delivery of major trauma care. It does not cover services for people with burns.\nThis guideline covers the assessment and early management of spinal column and spinal cord injury in pre-hospital settings (including ambulance services), emergency departments and major trauma centres. It covers traumatic injuries to the spine but does not cover spinal injury caused by a disease. It aims to reduce death and disability by improving the quality of emergency and urgent care.\nThis guideline covers assessing and managing suspected or confirmed cirrhosis in people who are 16 years or older. It aims to improve how cirrhosis is identified and diagnosed. It recommends tools to assess the severity of cirrhosis and gives advice on monitoring people with cirrhosis to detect and manage complications early, and referral criteria for tertiary care.\nThis guideline covers safe and effective prescribing of strong opioids for pain relief in adults with advanced and progressive disease. It aims to clarify the clinical pathway for prescribing and help to improve pain management and patient safety. Care during the last 2 to 3 days of life is covered by care of dying adults in the last days of life .\nThis guideline covers how upper gastrointestinal bleeding can be effectively managed in adults and young people aged 16 years and older. It aims to identify which diagnostic and therapeutic steps are useful so hospitals can develop a structure in which clinical teams can deliver an optimum service for people who develop this condition.\nThis guideline covers diagnosing and managing suspected or confirmed autism spectrum disorder (autism, Asperger’s syndrome and atypical autism) in people aged 18 and over. It aims to improve access and engagement with interventions and services, and the experience of care, for people with autism.\nThis guideline covers the longer-term psychological treatment and management of self-harm in people aged 8 and over. It aims to improve the quality of care and support for people who self harm and covers both single and recurrent episodes of self-harm.\nThis guideline covers assessment and referral for anaphylaxis. It aims to improve the quality of care for people with suspected anaphylaxis by detailing the assessments that are needed and recommending referral to specialist allergy services.\nThis guideline covers identifying people who wish to donate their organs after their death. It offers advice on how to approach families and carers of people who are nearing the end of life and how to seek consent for organ donation. It aims to promote discussion of organ donation as part of end-of-life care and to increase the number of organs available for people waiting for a transplant.\nThis guideline covers managing acute painful sickle cell episodes in children, young people and adults who present at hospital, from presentation until when they are discharged. It aims to reduce variation in how acute episodes are managed in hospital, focusing on effective, prompt and safe pain relief.\nThis guideline covers managing spasticity and co-existing motor disorders and their early musculoskeletal complications in children and young people (from birth up to their 19th birthday) with non-progressive brain disorders. It aims to reduce variation in practice and help healthcare professionals to select and use appropriate treatments.\nThis guideline covers assessing the risk of fragility fracture in people aged 18 and over with osteoporosis. It aims to provide guidance on the selection and use of risk assessment tools in the care of adults at risk of fragility fractures in all NHS settings.\nThis guideline covers detecting, diagnosing and treating women (18 years and older) who have, or are suspected of having, epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer or borderline ovarian cancer. It aims to enable earlier detection of ovarian cancer and improve initial treatment.\nThis guideline covers recognising and diagnosing autism spectrum disorder in children and young people from birth up to 19 years. It also covers referral. It aims to improve the experience of children, young people and those who care for them.", "pred_label": "__label__POS", "pred_score_pos": 0.9853951930999756} +{"content": "Parents\nCITE is opposed to the independent use of screens by children under two in out-of-home care. We found this INFOGRAPHIC from across the pond on Twitter: Keeping Under Fives Safe Online. These will protect children at home.\nMore Than Baby Talk\nThe University of North Carolina’s Frank Porter Graham Child Development Institute has just published “More Than Baby Talk,” an easily-readable and free online guide to igniting the communication and language skills of infants and toddlers. This guide includes ten research-based recommendations for educators and parents.\n“\nBy using these strategies, educators and parents can provide children with the rich language exposure and opportunities they need to enhance their language and communication.", "pred_label": "__label__POS", "pred_score_pos": 0.6203388571739197} +{"content": "S&W Seed CompanyFind Ratings Reports\nFinancial Analysis\nS&W SEED CO's gross profit margin for the fourth quarter of its fiscal year 2021 has significantly increased when compared to the same period a year ago. Even though sales decreased, the net income has increased. S&W SEED CO has very weak liquidity. Currently, the Quick Ratio is 0.38 which clearly shows a lack of ability to cover short-term cash needs. The company's liquidity decreased from the same period a year ago, despite already having very weak liquidity to begin with. This would indicate deteriorating cash flow.\nDuring the same period, stockholders' equity (\"net worth\") has decreased by 8.63% from the same quarter last year. The key liquidity measurements indicate that the company is in a position in which financial difficulties could develop in the near future.\nSTOCKS TO BUY: TheStreet Quant Ratings has identified a handful of stocks that can potentially TRIPLE in the next 12-months. To learn more visit www.TheStreetRatings.com.\nIncome Statement Q4 FY21 Q4 FY20 Net Sales ($mil) 22.77 25.87 EBITDA ($mil) -3.81 -4.27 EBIT ($mil) -5.15 -5.68 Net Income ($mil) -1.68 -4.8\nBalance Sheet Q4 FY21 Q4 FY20 Cash & Equiv. ($mil) 3.53 4.12 Total Assets ($mil) 151.47 155.96 Total Debt ($mil) 51.72 47.53 Equity ($mil) 74.42 81.46\nProfitability Q4 FY21 Q4 FY20 Gross Profit Margin 16.2 12.54 EBITDA Margin -16.73 -16.49 Operating Margin -22.63 -21.97 Sales Turnover 0.55 0.51 Return on Assets -12.65 -12.61 Return on Equity -25.76 -24.15\nDebt Q4 FY21 Q4 FY20 Current Ratio 1.44 1.68 Debt/Capital 0.41 0.37 Interest Expense 0.73 0.75 Interest Coverage -7.02 -7.59\nShare Data Q4 FY21 Q4 FY20 Shares outstanding (mil) 36.75 33.43 Div / share 0.0 0.0 EPS -0.05 -0.14 Book value / share 2.03 2.44 Institutional Own % n/a n/a Avg Daily Volume 77292.0 66998.0\nValuation\nSELL. This stock’s P/E ratio is negative, making its value useless in the assessment of premium or discount valuation, only displaying that the company has negative earnings per share. For additional comparison, its price-to-book ratio of 1.27 indicates a significant discount versus the S&P 500 average of 4.43 and a significant discount versus the subsector average of 4.13. The price-to-sales ratio is well below both the S&P 500 average and the subsector average, indicating a discount. After reviewing these and other key valuation criteria, S&W SEED CO proves to trade at a discount to investment alternatives.\nPrice/Earnings\nPrice/Cash Flow\nSANW NM Peers 22.53 SANW NM Peers 21.04\nNeutral. The absence of a valid P/E ratio happens when a stock can not be valued on the basis of a negative stream of earnings.\nSANW's P/E is negative making this valuation measure meaningless.\nNeutral. The P/CF ratio, a stock’s price divided by the company's cash flow from operations, is useful for comparing companies with different capital requirements or financing structures.\nSANW's P/CF is negative making the measure meaningless.\nPrice/Projected\nEarnings\nPrice to\nEarnings/Growth\nSANW NM Peers 19.96 SANW NA Peers 6.93\nNeutral. The absence of a valid price-to-projected earnings ratio happens when a stock can not be valued on the basis of a negative expected future earnings.\nSANW's ratio is negative making this valuation measure meaningless.\nNeutral. The PEG ratio is the stock’s P/E divided by the consensus estimate of long-term earnings growth. Faster growth can justify higher price multiples.\nRatio not available.\nPrice/Book\nEarnings Growth\nSANW 1.27 Peers 4.13 SANW 5.09 Peers 136.64\nDiscount. A lower price-to-book ratio makes a stock more attractive to investors seeking stocks with lower market values per dollar of equity on the balance sheet.\nSANW is trading at a significant discount to its peers.\nLower. Elevated earnings growth rates can lead to capital appreciation and justify higher price-to-earnings ratios.\nHowever, SANW is expected to significantly trail its peers on the basis of its earnings growth rate.\nPrice/Sales\nSales Growth\nSANW 1.13 Peers 2.33 SANW 5.61 Peers 8.48\nDiscount. In the absence of P/E and P/B multiples, the price-to-sales ratio can display the value investors are placing on each dollar of sales.\nSANW is trading at a significant discount to its subsector on this measurement.\nLower. A sales growth rate that trails the subsector implies that a company is losing market share.\nSANW significantly trails its peers on the basis of sales growth.", "pred_label": "__label__POS", "pred_score_pos": 0.6431418061256409} +{"content": "My research explores the experiences of criminal justice involved individuals with a particular focus on community justice alternatives, such as restorative justice and bail. I draw from sociological and criminological theories that account for interactional dynamics, emotion, and punishment.\nMy research is also informed by principles of community engaged scholarship. Currently, I am lead researcher on a provincial study exploring Youth Justice Committees, a program model of restorative justice, in partnership with the Ministry of Children, Community and Social Services.\nMy faculty position is associated with and located at the University of Guelph-Humber, Justice Studies.", "pred_label": "__label__POS", "pred_score_pos": 0.9905853271484375} +{"content": "All branches of the military require affordable mobile shelter systems that offer rapid deployment. These military structures serve an essential role, and need to be:\nDurable Portable Easy to maintain\nEdge is proud to support all branches of the military by providing innovative military shelter solutions. Whether you need to house a small squad or a large platoon, Edge is a military shelter manufacturer that quickly addresses your needs.\nAs one of the leading military shelter manufacturers, Edge offers state-of-the-art structures that meet many needs. Our mobile shelter systems with military applications include:\nOur truss arch fabric building system is considered one of the most diverse structures available, and is an ideal mobile shelter system for the military. Edge’s truss structure provides the following benefits:\nRelocatable Naturally ventilated Easily installed Cost effective Easily cleaned Soundproof\nThis quickly deployable shelter features three main components: the frame, the fabric, and the foundation. This simple design eliminates the need for extra materials, which minimizes installation time.\nOur fabric buildings are customizable to suit your military shelter needs, easily relocated, and include a 15- to 25-year warranty.\nEdge’s economic fabric structures are ideal for use as temporary military structures. Our structures are built without posts or beams, maximizing your storage capacity. Our cost-effective facilities are priced $10,000 to $20,000 lower than standard structures, giving our economic solutions the most competitive prices on the market. Our economic structures are ideal for:\nStoring aircraft Emergency shelters Maintenance facilities\nEdge’s structures are built to last. We guarantee a lifespan of 15 to 40 years for our steel-framed solutions.\nEdge takes pride in providing a comprehensive approach that challenges the industry status quo. We go the extra mile by providing the following services:\nWe understand that the installation process for each military shelter is unique, which is why Edge offers installation assistance. Our supply and install process follows these steps:\nOur team of experts conducts a full site analysis and determines which fabric structure best suits your needs. We design your structure by customizing the framework, materials, and anchoring system to support the foundation. We develop the steel frame and durable fabric and oversee delivery to your site. Our expert installation crew arrives at your location and begins installation. Once installation is complete, our team cleans up the site and performs a final inspection.\nOur fabric buildings are designed to last, but every structure eventually requires repair. Some of the common signs that repair is needed include:\nFabric tears Water stains Rusted frame\nEdge provides do-it-yourself repair kits that allow you to easily repair small tears in the fabric. Each repair kit comes with instructions, repair tape, and an industry-standard solution for minor fabric repairs.\nOur experienced professionals inspect your structure for damage and recommend a licensed contractor to perform necessary repairs for more significant problems. Edge is a comprehensive contractor, meaning you don’t have to outsource repairs to multiple vendors.\nSometimes, fabric building materials are damaged beyond repair. When that happens, Edge offers fabric cover replacement services that keep your structure usable. Our services are available for both our structures and those installed by other contractors. Our precise measurements mean your new cover will be a perfect fit.\nEdge specializes in dismantling and relocating our mobile shelter systems to meet the needs of our military partners. All of our military structures are relocatable, and we perform site analysis throughout the relocation process to determine the best solutions.\nAs a comprehensive military shelter manufacturer, Edge specializes in mobile shelter systems for the military. Our military shelters feature multiple foundation options and can be constructed on nearly any surface. We’re committed to reducing upfront costs and offer multiple purchasing and leasing options. Contact Edge today if you’re looking for military shelters that feature simple system designs.", "pred_label": "__label__POS", "pred_score_pos": 0.70082688331604} +{"content": "This research was aimed to investigate how significant the implementation of POEW model improved the students? writing ability. It was conducted using a quasi-experimental method with two pretest-posttest group design. It was implemented to the third semester students of English department of Universitas Muhammadiyah Parepare in academic year 2016/2017. At first, the researcher implemented POEW model to treat the students in teaching writing. After that, they were tested to find out their ability after being treated through POEW model. Data were analyzed quantitatively using 21.0 version of SPSS program.The result indicated that the students who were treated through POEW model have significant improvement in their writing ability than the students who were not. It is found that the significant value (0.000) was lower than the probability value (0.05). This means that there was a significant difference between the students? writing ability before and after being taught through POEW model where the students? writing ability improved significantly in posttest (after being taught through POEW model). The mean score of posttest of the students in experimental class (72.40) was higher than the students in control class (62.46) which indicated that the students ability in the experimental class was better than the students in control class. The students ability in experimental class was improved from 61.24 to 72.40 while in control class only from 61.36 to 62.46. Besides that, the standar deviation in experimental class (7.832) was also lower than in control class (8.364) which indicated that the students ability in experimental class was slightly similar to control class\nCopyrights © 2017", "pred_label": "__label__POS", "pred_score_pos": 0.917381763458252} +{"content": "The National Birth Defects Prevention Network, an organization dedicated to birth defects surveillance, research, and prevention, recently recognized University of Iowa Professor of Epidemiology Paul Romitti with the organization’s prestigious Godfrey P. Oakley, Jr. Award.\nThe award, presented last month at the NBDPN’s national meeting in Arlington, VA, is given to an individual who has made significant lifetime contributions to the field of birth defects.\nRomitti directs the Iowa Registry for Congenital and Inherited Disorders, a collaborative program of the UI College of Public Health and the Iowa Department of Public Health. He previously served NBDPN as Data Committee Chair, Executive Committee Member, and President for the organization.\nThe award is named for Godfrey Oakley, the former Director of the Division of Birth Defects and Developmental Disabilities at the Centers for Disease Control and Prevention, who was instrumental in setting the CDC birth defects agenda and in focusing national attention on the effects of folic acid in preventing neural tube defects.", "pred_label": "__label__POS", "pred_score_pos": 0.8362846970558167} +{"content": "The aim of this study was to evaluate the feasibility and potential efficacy of a WhatsApp-based physical activity for children with autism spectrum disorder (ASD). Fourteen parents and their children with ASD participated in the study. The intervention included parents conducting physical activities with their children with ASD for 4 weeks. Physical activity contents were provided to parents via the WhatsApp group. The data were collected through the Leisure Time Exercise Questionnaire and a feasibility questionnaire adapted from previous studies examining the feasibility of web-based physical activities. Parents reported that WhatsApp-based physical activities were a feasible intervention to increase the physical activity level of their children with ASD and stated that the contents of the physical activity shared in the WhatsApp group were useful. The findings provided preliminary evidence for the use of WhatsApp-based physical activities to increase the physical activity level of children with ASD who stay at home due to the pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.991417646408081} +{"content": "Senses are like muscles: use them or lose them. Most of us overly rely on vision. This is a workout plan for your other senses.\nThe crucial mindset shift that helps new habits stick.\nIt’s not about the outcome.\nWisdom from Alan Watts teaches us to ignore the pressure to “finish strong” and “get it over with.” The point of dancing is to dance.\nTo be truly realized we must get to the point where we’re no longer seeking.\nWhat if life is not happening to you or for you, but rather through you?\nWe often don’t realize the habitual ways we tense against life, and how this impacts our physical health and wellness.", "pred_label": "__label__POS", "pred_score_pos": 0.9998334050178528} +{"content": "Dear GW Community,\nMany of our community members are planning travel over the upcoming Fall Break and the Thanksgiving holiday. As you make your plans, we encourage you to review guidance from the Centers for Disease Control and Prevention (CDC) on how to protect yourself and others when you travel. Wear a mask on planes, buses, trains and other forms of public transportation traveling into, within or out of the United States, as required. Follow all state, local or international recommendations and requirements, including mask wearing and social distancing. Wear a mask in crowded outdoor settings and for activities with close contact with others who are not fully vaccinated.\nHolidays and celebrations are often a time to gather with family and friends. However, they can also be risky for COVID-19 if you are in close proximity to others with whom you do not normally live, especially if they are unvaccinated. Here are some tips for safe celebrations and gatherings:\nHave conversations ahead of time to understand expectations of celebrating together. Do not attend if you have any symptoms of COVID or have been recently exposed, and ask the same of others.Have outdoor celebrations if possible. If celebrating indoors in a group, and if not actively eating and drinking, wear a mask. If celebrating indoors, and weather permitting, open windows to allow fresh air.\nFollowing your travel, please be aware of testing and quarantine requirements and recommendations.\nIf you are fully vaccinated: You are strongly encouraged to schedule a COVID-19 test on your first day back to campus after travel. You are advised to self-monitor for symptoms of COVID-19 for 14 days after travel. You may schedule a test at GW or submit results from an external test site. If you have an exemption to GW’s vaccine requirement and are unvaccinated: You must report any travel outside of D.C., Maryland or Virginia in your daily symptom screener. Upon returning to the District, per D.C. Health guidance, you must follow the protocol for travel quarantine. Thank you for your continued cooperation, and we wish you safe travels.", "pred_label": "__label__POS", "pred_score_pos": 0.8811067938804626} +{"content": "When parents want an alternative to public schools, they have options. Among these, classical education differs quite profoundly from traditional public schools. Guided by the Western canon, classical schools often orient themselves toward the liberal arts with a foundation of Greek and Roman traditions.\nAs we all seek academic excellence for our children, many parents find their alternative in an option such as this. Oftentimes, parents rate good teachers and strong academics as their priorities in evaluating a school.\nHowever, they also tend to rank both safety and extracurricular activities as priorities. Additionally, many parents value their personal education and religious views. With the diverse, multicultural society of the United States, it’s difficult for some families to feel their values in public schools.\nAs an alternative to public schools, classical schools serve a diverse range of students while offering their values and philosophy.\nClassical Education: An Overview\nModern classical schools draw their inspiration from Greek and Roman traditions. They focus on the foundations of Western society: art, language, and literature. In the past, educators synthesized this tradition with the values of Christianity.\nThen, they established a framework to educate children. As such, many of the philosophers, statesmen, and theologians of the West benefitted from a classical education. Today, this educational model includes additional languages and literature that help to uphold the virtue of academic excellence.\nThe Problem with Public Schools for Some Parents\nWhy do so many families seek an alternative to public schools? Today, public schools in the United States sustain influence from many different schools of thought. Often, this varies even from school to school and district to district – within a single state.\nSome schools model the curriculum on the ideals of traditional figures. Others pull influence from a more critical lens. Still others teach a curriculum that ignores significant aspects of our history.\nBecause the public school system is so localized, there isn’t one dominant course structure. For many parents, this constitutes an incredible issue. Based on where they live, the local school system might not reflect their values.\nA Contemporary Alternative to Public Schools\nToday, we find the classical education model in small schools, private schools, public charter schools, and homeschool environments. In religious schools, classical education often incorporates Biblical text and training. These classical Christian schools offer rigorous education from the perspective of Judeo-Christian values.\nMoreover, some Catholic schools also revive the classical school model while some parochial schools offer their parishioners this model.\nIn areas that lack a classical option, parents who homeschool their children often become ardent supporters of the model. Classical homeschool programs provide parents with the information needed to educate their children. Often, faith plays an essential component for these families as well.\nStill, it’s important to remember that classical education is not restricted to these environments. Several public charter schools utilize aspects of classical learning. Often, these schools provide disadvantaged students with a stronger education.\nIn turn, it offers them a better chance to prepare for college.\nThe Difference in Classical Education\nGenerally, public schools in the United States aim to prepare students for a specific grade. They begin with kindergarten and end with the 12th grade. However, those seeking an alternative to public schools find the “trivium” in a classical school.\nThis refers to the first three arts: grammar, logic, and rhetoric. While many schools use conventional grade levels, this structure informs the model of many classical schools.\nGrammar in this sense does not refer to the rules of language. Instead, it means the earliest years of the child’s education. At this time, the goal is to develop a foundation for their education with a base of knowledge.\nIn the logic stage, schools build upon the grammar stage. At this level, students learn how to outline and evaluate an argument. Moreover, students begin to consider narratives from literature and practice explaining facts.\nThe rhetoric stage offers students the opportunity to express their thoughts productively. They use the knowledge and tools of the prior stages to learn how to make arguments. This is both written and oral, allowing students to become comfortable with both.\nGenerally speaking, classical education relies on the Socratic method. This pits ideas against one another in the pursuit of knowledge and truth. By challenging students to explore ideas, families have an alternative to public schools.\nMoreover, it allows students to seek truth throughout their education and life. At the surface level, this might not appear to be an alternative to public schools.\nChildren learn math, English, languages, history, science, and more. However, it’s the method of education that differs. Perhaps the most important difference for parents is the insistence that values matter.\nIn other schools, the value-neutrality might fail to produce an environment that fosters education. However, education often requires a shared understanding of the fundamentals. In this model, children develop a way to digest and interpret facts as they develop and defend their values.\nIs Classical Education Right for My Child?\nToo often, families who seek an alternative to public schools feel they have no option for their children. With our classical school, Houston families have an alternative built around values and community.\nWhen a student enters a classical school, they receive a structured education that challenges and uplifts them. Building from the foundation of American society and Western civilization, they receive the skills necessary to succeed.\nThrough classical education, we foster a lifelong love of learning. Our goal is to turn students into seekers of knowledge who pursue truth through critical thinking. We place great value on the ability of our students to think critically and engage in civil debate.\nOftentimes, classical schools across the country provide a curriculum that adapts to students of various backgrounds. Through this, we transform students from an array of backgrounds into citizens and scholars. Moreover, we prepare them for modern challenges with a foundation in timeless tradition.\nTo learn more about our classical school in Houston, call us today. Schedule a visit to see whether our school is right for your family.", "pred_label": "__label__POS", "pred_score_pos": 0.7272722721099854} +{"content": "The defensive midfielder is a relatively modern position. Players like Claude Makelele, Yaya Toure, Sergio Busquets, and Paul Scholes thrived in the holding midfield role. The defensive midfield role has to do two things on the pitch: break down build-up play from the opposing team, and distribute the ball from the defense into the midfielders or forwards.\nHowever, a successful defensive midfielder, above all, must be able to read the game. The positioning of the defensive mid alone can make a massive difference in the outcome of a match. There are three primary defensive midfield roles: anchor, ball-winning, and the regista.\nAnchor\nThe anchor sits right in front of his defensive line. Usually, their job is to apply pressure for any opponent breaking through the midfield and to join the defense when on the back foot. Offensively, the anchorman is instructed to play the ball to his playmaker to begin an attack.\nBall-winning\nBall-winning midfielders don’t sit quite as deep as anchors, but they are primarily responsible for defense-oriented duties as well. Because of this, ball-winning midfielders are often underrated in their support for the attack.\nIn some situations, when the ball-midfielder plays alone in his or her line, positioning becomes essential. On defense, the ball winning-midfielder has a lot of ground to cover to assist all positions in defense. Alternatively, on offense, the ball-winning midfielder plays some role in possession and distribution and is expected to play (and pass) simply and keep the ball.\nIn the 16/17 Premier League season, N’golo Kante boasted 65% tackle success and averaged 60 passes per game, earning him the player of the season award. Regista/Playmaker\nThe regista is only a defensive midfielder due to their deep positioning. His or her main priority is to distribute the ball, and link the defense to the midfield. As a playmaker, the regista must move constantly to keep an open lane with the ball. A playmaker who is available and able to receive the ball can make the difference between winning and losing. Positioning is key.\nTechnical Ability\nMidfield legends Paul Scholes, Xavi, and Andrea Pirlo thrived in the regista role. Their athletic limitations did not factor into their performances because they had the vision to be at the right place at the right time. However, positioning alone is not enough. Being the focal point of the team, the regista receives the ball often during a match. More recently,\nJorginho made an average of 79 passes per match in the Premier League. A player in this role must have the technical ability to receive the ball under pressure and distribute it to his teammates.\nAdditionally, in a system that plays with a playmaker, the team moves and plays to the pace that the regista dictates. Because of this, the regista must understand the game well and be very technical in keeping possession and distributing the ball to start an attack or escape a press.", "pred_label": "__label__POS", "pred_score_pos": 0.9570688009262085} +{"content": "Table of Contents\nElliptic, a London-based Blockchain analytics firm, identified the Bitcoin wallet used by the ransomware group responsible for the Colonial Pipeline attack and its extortion amount. According to a report from the\nBlockchain analytics firm Elliptic, the ransomware gang Darkside received a ransom payment from Colonial Pipeline of 75 Bitcoin, or roughly $5 million, following the cyberattack on its operations on May 8. Colonial Pipeline was targeted in a cyber attack which led to widespread fuel shortages and has been the most challenging cyber-attack on U.S. vital infrastructure to date. The FBI and security researchers discovered the Darkside ransomware gang’s operation in August 2020 and nearly 9 months later in May 2021, they confirmed the involvement of the Darkside ransomware gang in the attack on Colonial Pipeline. Ransomware-as-a-service model:\nThere were just over $90 million in bitcoin payments to DarkSide from 47 distinct wallets. According to DarkTracer, 99 organizations have been attacked by the DarkSide malware and so far, they seem to have paid an average of $1.9 million in ransoms. In addition to targeting only big companies, DarkSide specifically forbids affiliates from placing ransomware on organizations in a wide range of industries including healthcare, funeral services, education, the public sector, and non-profits.\nIn addition to this, the company also discovered a ransomware payment made by Brenntag, a large chemical distributor in Germany, totaling about $ 4.4 million. According to Elliptic, the group’s wallet has been active since March 4, 2021, and has received 57 payments from 21 different wallets. Some ransomware groups, including DarkSide and other ransomware groups, use the ransomware-as-a-service model, where the malware’s designers can effectively outsource the actual hacking and infecting of a target and split the ransom.\nSince then, the practice has democratized ransomware, allowing less experienced cybercriminals a chance to scam the system without technical knowledge. “In this operating model, the malware is created by the ransomware developer, while the ransomware affiliate is responsible for infecting the target computer system and negotiating the ransom payment with the victim organization. This new business model has revolutionized ransomware, opening it up to those who do not have the technical capability to create malware but are willing and able to infiltrate a target organization,” Elliptic said.", "pred_label": "__label__POS", "pred_score_pos": 0.8876699209213257} +{"content": "This dataset provides the data presented in our paper \"Neuronal figure-ground responses in primate primary auditory cortex\".
A critical aspect of auditory scene analysis is the ability to extract a sound of relevance (figure) from a background of competing sounds (ground) such as when we hear a speaker in a cafe. This is formally known as auditory figure-ground segregation. This is colloquially known as \"cocktail party problem\".
To understand how the brain segregates overlapping sounds, we need to record from neurons, i.e. single cells in the brain. Since systematic single cell brain recordings are not suitable to perform in humans, we need to use animals in this research. Monkeys are best suited as animal models of human auditory perception due to their similar auditory abilities and similar organization of their auditory brain as humans. However, before we generalize the findings from monkeys to humans, we need to establish that monkeys utilize similar brain regions as humans for auditory figure ground segregation.
To compare the underlying brain network in humans and monkeys, we need to employ sounds that are equally relevant to both species. So these sounds can neither be human speech nor monkey calls. So we have created artificial sounds that contain (i) an auditory object made of tones repeating in time and (2) \"background\" masker elements which overlap in time and frequency with the 'object'. Extraction of this auditory object requires integration across both time and frequency similar to extraction of a voice in a noisy party. Thus, these artificial sounds simulate the challenges faced in real-world listening yet are devoid of semantic confounds.
Here, we investigated auditory figure-ground segregation based on neuronal multi-unit activity of rhesus macaques that attentively listened to SFG stimuli. The experiment was designed as Go/No-go figure-detection task. The detection of auditory figures was indicated with a touch bar release. The target-to-masker ratio (figure coherence) was pseudorandomly changed from trial to trial (either 8 or 12 elements, equal probability). We presented auditory figures in 60% of trials. The remaining trials contained no temporally coherent elements (catch trials).
We report figure-ground modulation of neuronal multi-unit activity across the auditory cortex, including the primary auditory cortex (A1).
", "pred_label": "__label__POS", "pred_score_pos": 0.9626624584197998} +{"content": "Year Published: 2021 Journal\nEClinicalMedicine\nAuthors\nGiuseppe Fiorentino, Antonietta Coppola, Raffaele Izzo, Anna Annunziata, Mariano Bernardo, Angela Lombardi, Valentina Trimarco, Gaetano Santulli, Bruno Trimarco\nMethods\n\"This is a parallel-group, double-blind, randomized, placebo-controlled trial conducted on patients hospitalized for severe COVID-19. Patients received 1.66 g L-arginine twice a day or placebo, administered orally. The primary efficacy endpoint was a reduction in respiratory support assessed 10 and 20 days after randomization. Secondary outcomes were the length of in-hospital stay, the time to normalization of lymphocyte number, and the time to obtain a negative real-time reverse transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2 on nasopharyngeal swab.\"\nKey Findings\n\"We present here the results of the initial interim analysis on the first 101 patients. No treatment-emergent serious adverse events were attributable to L-arginine. At 10-day evaluation, 71.1% of patients in the L-arginine arm and 44.4% in the placebo arm (p < 0.01) had the respiratory support reduced; however, a significant difference was not detected 20 days after randomization. Strikingly, patients treated with L-arginine exhibited a significantly reduced in-hospital stay vs placebo, with a median (interquartile range 25th,75th percentile) of 46 days (45,46) in the placebo group vs 25 days (21,26) in the L-arginine group (p < 0.0001); these findings were also confirmed after adjusting for potential confounders including age, duration of symptoms, comorbidities, D-dimer, as well as antiviral and anticoagulant treatments. The other secondary outcomes were not significantly different between groups. Interpretation In this interim analysis, adding oral L-arginine to standard therapy in patients with severe COVID-19 significantly decreases the length of hospitalization and reduces the respiratory support at 10 but not at 20 days after starting the treatment.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9209851026535034} +{"content": "Please note that this is not a complete list of resources. The Agency will be updating this list regularly. If you know of relevant resources not listed here please email them to agr.covidresponse@vermont.gov for inclusion\nVermont has long been proud of its farmers and producers, and now, the role of farmers and producers is even more pivotal. The feed supplier, dairy farmer, vegetable grower, grocery store retail clerk—and everyone in between—generate our food production and supply and are essential to our safety as we work through this public health emergency.", "pred_label": "__label__POS", "pred_score_pos": 0.5936803817749023} +{"content": "Karoo Large to Giant Breed Puppy’s super-premium formulation sustains the boundless energy of youth, meets the demands of a rapidly growing body while laying strong foundations for a happy and healthy future for your puppy. The nutrient-rich meat and poultry proteins, added vitamins (including C, D and E), minerals and high levels of antioxidants found in every enticing, balanced bowl support overall physical well-being and help maintain a healthy immune system. Added Chondroitin and Glucosamine provide support for growing joints and cartilage.\nIngredients:\nMaze*(may contain GMO), Chicken, rice, lamb, poultry oil, ostrich, beet pulp, brewers yeast, natural flavouring agents, fish oil powder, salt and fatty acids with glucosamine and chondroitin. Added essential minerals and vitamins and approved antioxidants. (may contain GMO*s), Omega 6 and 3. Milk powder (lactose induced). Added Chondroitin and Glucosamine.\nGuaranteed Analysis:\nCrude protein: 26.5% | Moisture: 12% | Total fat: 12.5% | Crude fibre: 3% | Crude ash: 7% | Calcium: 1.3% | Phosphorus: 0.9% | Omega-6 fatty acids: 2% | Omega-3 fatty acids: 1% | DHA: 0.25% | Glycaemic carbohydrates: 34% | Taurine: 700 mg/kg | Glucosamine: 640 mg/kg | Chondroitin: 330 mg/kg | Metabolisable energy: 365 kcal/100g", "pred_label": "__label__POS", "pred_score_pos": 0.6668412685394287} +{"content": "Commentary: Supply Chain Laws to Fight Deforestation Must Back Indigenous Rights\nEfforts to save the world’s forests could soon get a boost from proposed laws in the European Union, the United Kingdom and the United States to restrict the import of agricultural commodities linked to deforestation. These three markets’ consumption of such products is a driver of a quarter of all deforestation linked to international trade.\nProtecting carbon sinks—ecosystems like forests that absorb and store planet-warming gases—is crucial to address the climate crisis, so this is welcome news. But these proposed laws would be more effective if they also protected the rights of Indigenous peoples, who have proven to be among the most reliable forest custodians...\n...This is not to say states should offload their responsibility for enforcing environmental laws to Indigenous peoples—only that they should recognize them as essential allies, uphold their land rights, and support their successful initiatives to monitor and reduce deforestation...\n...Harvesting forest products is an integral part of many Indigenous peoples’ livelihoods, and serves as a continuous incentive to protect forests, along with cultural and spiritual factors. Moreover, their traditional knowledge about forest management makes Indigenous peoples effective stewards of local ecosystems.\nTo play this role, however, these communities need protection from violence and intimidation, and from efforts to drive them off or deny them access to or control over their traditional territories.\nThe solution is laws that protect forests\nand people. At a minimum, laws that regulate imports of agricultural commodities should require businesses to ensure their products are not associated with acts of violence and intimidation against Indigenous peoples, abuses of their land tenure rights or failure to obtain their free, prior and informed consent to projects that may impair their rights. These laws should bar agricultural commodities credibly alleged to be linked to abuses of these rights from entering markets.\nThis would require businesses to identify where the agricultural commodities they use in their products come from, assess the risk their operations pose to Indigenous peoples’ exercise of their rights, and mitigate these risks. They should ensure that communities’ consent is sought in good faith when business activities affect them and conduct local audits to determine whether their mitigation measures are effective, including by consulting forest guardians...", "pred_label": "__label__POS", "pred_score_pos": 0.8573486804962158} +{"content": "ISBN : 9780198827009\nThis study provides the first postsecular account of the moral revolution that Britain experienced in the 1960s. Beginning from the groundbreaking premise that secularity is not a mere absence, but an invented culture, it argues that a new form of British secularity achieved cultural dominance during an abrupt cultural revolution which occurred in the late 1950s and early 1960s. This moral revolution had little to do with affluence or technology, but was most centrally a cultural response to the terrors of the Cold War, which pitted Christian Britain against the secular Soviet Union. By exploring contemporary prophecies of the inevitable arrival of 'the secular society', Sam Brewitt-Taylor shows that, ironically, British secularity was given decisive initial momentum by theologically radical Christians, who destigmatized the idea of 'modern secularity' and made it available for appropriation by a wide range of Sixties actors. Further than this, radical Christians played a significant contributory role in deciding what kind of secularity Britain's Sixties would adopt, by narrating Britain's moral revolution as globalist, individualist, anti-authoritarian, sexually libertarian, and politically egalitarian. In all these ways, radical Christians played a highly significant role in the early stages of Britain's Sixties.\nIntroduction: Christian radicalism and the invented revolutions of the 1960s\n1 World crisis and the making of Christian radicalism, c.1938-1957 2 Christian radicalism and the enactment of secular theology 3 Christian radicalism and the hope of Christian unity 4 Christian radicalism and the hope of transcending 'religion' 5 Christian radicalism and the hope of escaping human authority 6 Christian radicalism and the hope of a revolution of love 7 Christian radicalism and the hope of revolutionary social justice Conclusion: Crisis, eschatology, and the re-invention of British modernity Bibliography", "pred_label": "__label__POS", "pred_score_pos": 0.6160364151000977} +{"content": "A just-published report suggests the inventory in the Vancouver real estate market has reached a low not seen since\n2016.\nThe Q3 report posted Thursday morning by the Real Estate Board of Greater Vancouver noted the number of active\nlistings was low over the summer months, a trend that isn't exactly new in the region.\n\"Since the last half of 2019, the total inventory of homes for sale in the market has been operating at near-historic lows\ndespite higher-than-typical sales and new listing activity,\" the REBGV wrote.\n\"The increasing correlation between sales and new listings over the pandemic is consistent with more buyers selling their\ncurrent homes and purchasing other, typically larger, homes,\" the board said.\nIt described the trend board members are seeing since early 2021 as the market \"settling down,\" and said a monthly survey\npointed to first-time and move-up buyers becoming a larger portion of total home sales.\nWhile inventory is down, prices are generally not.\nThe August 2021 benchmark price – a measure that is not an average or median but is calculated based on the typical type,\nsize and age of home available in a region – was a record-breaking $1,176,600.\nLooking at detached homes alone, the benchmark was $1,807,000. Benchmarks for attached homes and condos were at\n$952,600 and $735,100 in the market.\nWhile growth in prices hasn't been to the extent seen at other times in the local market, things are expected to pick up again\nin the fall.\nThe board forecast an upward pressure due to above-average sales volumes, coupled with the low inventory noted previously.\nIt says buyers and sellers should expect new listings and sales in Q4 to remain near to long-term averages, and expects the\nnumber of listings to increase, but at a level still well below the norm.", "pred_label": "__label__POS", "pred_score_pos": 0.588681697845459} +{"content": "Trends Impacting The Design of Healthcare Environments\nIt’s an old design axiom that\nform follows function. This suggestion is nowhere more true than in the healthcare environment. In a habitat that is so completely focused on results, those results and the needs of patients influence every element of design. Additionally, new technologies, practices, and emergencies appear at an accelerating rate. These developments also factor into the critical thought for effective environmental design. While some elements are constant, such as the necessity for efficiency in healthcare design work, others develop and change over time. These current trends will steer the direction of the way medical spaces evolve in the coming years. Related: Mobile Workstations Focus on Employee Wellness\nWhile the COVID-19 crisis highlighted the problem to a highly stark degree, healthcare workers possess a long-standing reputation for hard work.\nLong hours, high levels of stress, and life-or-death situations create a toll on healthcare professionals frequently unseen in other career paths. Many nurses and doctors express high levels of burnout, particularly after extended emergencies like COVID-19, and people are paying attention.\nThe result in the design world is that hospitals and healthcare facilities will begin to reimagine their employee spaces. The goal will be to\ncreate better recuperative environments for healthcare workers to help prevent burnout. Facilities may start taking a cue from corporate backgrounds, establishing outdoor recreation spaces, more wellness-focused break rooms, and areas for socialization. Embracing New Technology\nNew technologies consistently have a substantial impact on design. Between the development of\nrobotics and artificial intelligence for medical facilities and wearable technologies to the growing demand for telemedicine, healthcare spaces will have to adapt to new technological needs. These solutions will range from reimagining waiting rooms and public spaces to developing efficient means of accommodating new devices. The result may be smaller waiting rooms due to lower demand for space from patients. It also suggests a need for dedicated space for practitioners to hold telemedicine appointments. These might be small spaces with dedicated computer access where doctors can meet their patients virtually. Are you in the market for medical supplies and furniture? Check out Carsten’s to fulfill your needs! Cost Reduction\nA perennial concern is cost reduction, but with the recent economic woes, this factor has come to the forefront of people’s minds. The design challenges associated differ from those previously presented. Instead of focusing on new construction to accommodate medical requirements, projects are more\nlikely to move toward consolidation, renovation, and development of flexible-purpose spaces. Rather than developing brand new design solutions for new projects, design challenges will include retrofitting existing spaces for use in new and flexible ways. New projects will likely focus on revenue-generating options like operating rooms. Reactions to COVID-19 Space design is likely to respond to recent concerns raised by COVID-19. The new structure will avoid cross-contamination, which will require different types of spaces that allow hospitals to quickly and completely isolate them from the rest of the hospital. It may also include establishing atria where staff can remove PPE without letting it into the rest of the hospital. Also, it suggests rethinking shared areas. Waiting rooms may need to be redesigned or made smaller to reduce the risk of exposure. Likewise, shared workspaces may be redesigned, established with reduced capacity, or eliminated where possible. Flexibility and Resilience\nDealing with a worldwide pandemic has highlighted the necessity of flexibility and resilience in adapting to new challenges. During the pandemic, this problem was often tackled with hastily-constructed temporary work areas because the medical facilities themselves didn’t offer the kind of adaptability necessary to cope with surges of the size was seen. As a result, new design challenges emerge. These include\ndeveloping spaces that can readily change from one form to another. For instance, the new design paradigm might focus on open format work areas that can rapidly transform into care facilities to serve in sudden desperate situations. Related: Wall-mounted Work Stations Supply Line Sustainability\nAnother concern that came to the forefront recently was the consideration of supply lines for medical facilities. With many hospitals running out of critical supplies at crucial moments recently, it became clear that a new approach to supply lines was necessary. While the solutions employed may vary, the need for storage is genuine. Solutions may range from\nnew centralized offsite facilities designed to house stockpiles of supplies to adapting existing spaces onsite for storage. Creating efficient ways of accomplishing these goals will be a crucial design challenge going forward. Consumer-centered Thinking\nUntil recently, hospital design was focused almost entirely on critical functions. People designed waiting rooms to seat many people for short periods. They developed exam rooms to fit an exam table, a cabinet, and very little else. The vast majority of space and effort ensured that surgeries, tests, and examinations could be carried out efficiently and effectively. While this is still the primary goal of a successful design for a healthcare environment, there are growing demands regarding patients and their families. As a result,\nthe medical industry is looking more closely at consumer-oriented needs. This factor means a new focus on establishing spaces that offer comfort instead of just functionality. That includes a move toward private rooms for patients, which creates a design challenge for maximizing capacity. It also includes establishing separate bathrooms and sleeping spaces for patients’ friends and families during extended stays. The quality of these facilities will also be affected by consumer expectations. Hospital Specialization\nAs options evolve regarding outpatient treatment, telemedicine, and other alternative forms of care, the purposes of hospitals evolve as well.\nRather than maintaining their establishment as a one-stop shop for all medical concerns, they will increasingly focus on very ill patients. The result is that the forms hospitals take will begin to change, along with the focus of the design. This change will range between establishing spaces customized for specific ailments and areas designed for the longer-term stays associated with more severe illness. It will also focus on the necessary auxiliaries concerned, such as more and better facilities for the associates of very ill patients. Do you need help outfitting your medical environment? Go to Carsten’s now to find the help you need! Conclusion\nThere are many factors influencing the design of healthcare facilities, and they range from merely useful to the demands of consumers regarding comfort and aesthetic appeal. Combining these disparate needs into final design solutions represents a considerable challenge for the most knowledgeable designers. However, as we continue through the twenty-first century, the rate of change and associated challenges will only accelerate.\nRelated: Charting Supplies", "pred_label": "__label__POS", "pred_score_pos": 0.6667945384979248} +{"content": "Full metadata record\nDC Field Value Language dc.contributor.author 안성복 - dc.date.accessioned 2019-07-29T16:30:14Z - dc.date.available 2019-07-29T16:30:14Z - dc.date.issued 2018 - dc.identifier.issn 1047-2797 - dc.identifier.issn 1873-2585 - dc.identifier.other OAK-25126 - dc.identifier.uri https://dspace.ewha.ac.kr/handle/2015.oak/250219 - dc.description.abstract Purpose: To investigate whether the relationship between body mass index (BMI) and incident diabetes is modified by different alanine or aspartate aminotransferases (ALT or AST) levels. Methods: We carried out an analysis of 6484 participants aged 40 years or older using data from the Korean Genome Epidemiology Study. The serum aminotransferase levels were stratified into low and high groups according to the median values and classified into three groups: both low, either high, and both high. To assess the association between BMI and incident diabetes according to the serum aminotransferase levels, multiple logistic regression models were used. Results: In participants with high levels of both ALT and AST, compared with the first BMI quartile, the adjusted odds ratios for incident diabetes of the second, third, and fourth BMI quartiles were 1.72 (95% confidence interval, 0.84-3.55), 2.19 (1.11-4.33), and 3.08 (1.60-5.90), respectively (P trend <.001). In participants with either high ALT or AST, the adjusted odds ratios were 3.58 (1.23-10.41), 2.65 (0.90 7.76), and 5.28 (1.86-15.02), respectively (P trend =.005). However, in participants with both low ALT and AST levels, high BMI was not independently associated with the risk of incident diabetes. Conclusions: There was a strong association between BMI and incident diabetes among individuals with high aminotransferase levels, whereas no association was observed among those with low aminotransferase levels. (C) 2018 Elsevier Inc. All rights reserved. - dc.language English - dc.publisher ELSEVIER SCIENCE INC - dc.subject ALT - dc.subject AST - dc.subject Obesity - dc.subject Diabetes - dc.subject Korean - dc.title Aminotransferase levels, body mass index, and the risk of diabetes: a prospective cohort study - dc.type Article - dc.relation.issue 10 - dc.relation.volume 28 - dc.relation.index SCIE - dc.relation.index SCOPUS - dc.relation.startpage 675 - dc.relation.lastpage 680 - dc.relation.journaltitle ANNALS OF EPIDEMIOLOGY - dc.identifier.doi 10.1016/j.annepidem.2018.07.009 - dc.identifier.wosid WOS:000447244800001 - dc.author.google Song, Bo Mi - dc.author.google Kim, Hyeon Chang - dc.author.google Kim, Dae Jung - dc.author.google Ahn, Song Vogue - dc.author.google Kim, Kyoung Min - dc.author.google Lee, Ju-Mi - dc.author.google Koh, Sang-Baek - dc.author.google Suh, Il - dc.contributor.scopusid 안성복(47360986600) - dc.date.modifydate 20210915105720 -\nItems in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.", "pred_label": "__label__POS", "pred_score_pos": 0.9996922612190247} +{"content": "Potassium-Argon Dating Potassium-Argon (K-Ar) dating is the most widely applied technique of radiometric dating.\nWhat isotopes can be used for dating?\nThe most widely used radioactive cosmogenic isotope is carbon of mass 14 (14C), which provides a method of dating events that have occurred over roughly the past 60,000 years. This time spans the historic record and a significant part of the prehistoric record of humans.\nHow are minerals dated?\nTo establish the age of a rock or a fossil, researchers use some type of clock to determine the date it was formed. Geologists commonly use radiometric dating methods, based on the natural radioactive decay of certain elements such as potassium and carbon, as reliable clocks to date ancient events.\nOf the three basic rock types, igneous rocks are most suited for radiometric dating. Metamorphic rocks may also be radiometrically dated. However, radiometric dating generally yields the age of metamorphism, not the age of the original rock.", "pred_label": "__label__POS", "pred_score_pos": 0.9350823760032654} +{"content": "If your child has ADHD and you want to understand how to help them, here are some of our top recommendations.\nNumber One: Super-parenting for ADD\nDr Edward Hallowell has decades of experience working with children experiencing ADD. He argues that ADD is often misunderstood, and he has teamed up with top academic ADD researcher Peter S. Jensen to provide parents with a new approach to helping their child with ADD. Superparenting for ADD offers a specific game plan, including unconditional love, viewing the mirror traits and the cycle of excellence.\nNumber Two: Raising Boys With ADHD\nWritten by professionals who have sons of their own with ADHD. This book aims to empower parents to help their sons with ADHD succeed in school and throughout their lives. Filled with practical knowledge, resources and tools required to support parents in addressing the various strengths and challenges that boys with ADHD experience.\nNumber Three: Mindful Parenting for ADHD\nWritten by a pediatrician, this book aims to assist parents, and their children keep calm, flexible and in control. This book includes effective mindfulness techniques to overcome daily challenges experienced.\nNumber Four: Easy to Love but Hard to Raise\nThis book includes an anthology of personal experiences written by parents of children with ADD and ADHD, along with various other diagnoses. The written experiences of parents focus on honest feelings and lessons learned, epiphanies, commonplace and extraordinary experiences. Some of the topics include how children came to be diagnosed, the experience of dealing with problem behaviours, experiences with/feelings about treatment, school experiences, children’s social interactions, parent’s emotional and physical health, marriage, and other relationships.\nNumber Five: Thriving with ADHD Workbook for Kids\nThis book is filled with 60 fun activities to help children self-regulate, focus and succeed! With this book, parents can help their kids reframe how they think about ADHD and discover their unique talents. Topics include an overview of ADHD, skill-building exercises and action-oriented learning.\nNumber Six: Nowhere to Hide\nThis book focuses on a new way of looking at why kids with ADHD/LD struggle at school; it provides strategies to reduce stress and includes helpful rating scales, checklists and printable charts to use at school and home.\nNumber Seven: Boys Without Instructions\nWithin this book, Penny Wiliams shares her unfiltered thoughts and emotions during her progression through the learning curve of parenting a child with ADHD. This book exposes the genuine grit of the moment-by-moment peaks and valleys of this special parenthood.\nNumber Eight: 8 Keys to Parenting Children with ADHD\nThis book combines expert information with practical advice by sharing eight key concepts to help parents with their children with ADHD. The book focuses on developing and strengthening effective interpersonal skills in both parents and children.\nNumber Nine: What Your ADHD Child Wishes You Knew\nThis is an insightful and practical book where veteran psychologist Sharon Saline shares the words and inner struggles of children and teens living with ADHD, with a blueprint for achieving lasting success by working together.\nNumber Ten: ADHD: How To Parent A Happy Healthy Child With ADHD\nThis book aims to help parents discover what they can do for their child to flourish; it provides answers to questions and gives real-world solutions. Some of the topics included are: how to find the best therapy for your child, the importance of keeping an ADHD journal, hints and tips for avoiding meltdowns and reducing your stress levels.\nWe hope you found this list of 10 books for parents of children with ADHD helpful in your search. If any book stands out for you, let us know! What other books do you recommend? We’d love to hear them!", "pred_label": "__label__POS", "pred_score_pos": 0.5959906578063965} +{"content": "Bacteria and archaea have existed on Earth for billions of years—from surviving in Earth’s primeval, toxic environment to the oxygen-rich world we live in today. These microorganisms hold the mystery of the beginning of life on Earth and are valuable tools for scientific research and discovery. Without them, life as we know it would not exist.\nThese incredible organisms hold a unique fascination for many scientists. Bacteria, for example, not only play a critical role in human health and disease, they are essential for biogeochemical cycling, plant health, and decomposition. Understanding these organisms has led to numerous advancements in medicine, microbiome research, and agriculture.\nSimilarly, archaea have been a source of wonder for researchers who have been using these ancient organisms to explore the origins of life on Earth and other planets. Because of their ability to survive in extreme environments, archaea have also been an essential tool for biofuel production, bioremediation, and the development of innovative industrial biotechnologies.\nIt is because of the high reverence we have for microbial life at ATCC that we have been a leading innovator in microbial scientific discovery and a trusted resource of microbiological materials for nearly a century. We are continually expanding our collection of bacteria and archaea to ensure that researchers have the clinically and environmentally relevant strains needed to support their incredible research.\nExplore our vast collection of authenticated strains that support microbiome research, quality control testing, infectious disease research, extremophile studies, and more!\nDrug-resistant bacteria\nAntimicrobial-resistant bacteria are a growing concern around the globe. As more bacteria become resistant to existing antimicrobial treatments, researchers are investigating alternative therapies to stay ahead of these pathogens. To support this endeavor, ATCC provides the authenticated strains needed to make a difference in this critical field of research.Explore Now", "pred_label": "__label__POS", "pred_score_pos": 0.8805884122848511} +{"content": "Chocolate vine Common name: Chocolate vine Botanical name: Akebia quinata Management programme:Advisory Where is it originally from?\nOriginates in Japan, China, and Korea, it was given the name chocolate vine due to its fragrant vanilla or chocolate scented flowers.\nWhy is it a pest?\nGrows rapidly, forming a thick, smothering mat that prevents establishment of seedlings and native plants.\nWhere is it found?\nChocolate vine spreads via stem fragments and bird-dispersed seeds. It is tolerant to a wide range of conditions but prefers riparian zones, forest edges, wetlands, and urban areas.\nThere are no known sites in the Bay of Plenty.\nWhat does it look like? Climber with slender stems that are green when young, turning brown as they mature. Leaves are often described as ‘hand-shaped’ with a purple tinge that becomes blue-green when mature. Clusters of brown-purple flowers with a vanilla fragrance from August to October. Fruits are purple-violet flattened sausage-like pods. What are the rules? Advisory\nThe Bay of Plenty Regional Council does not enforce the control of advisory species. It is landowner/occupier responsibility to manage these pests. Council may provide advice on how to manage or control these species if required.\nHow do you get rid of it? Recommended: Dig out individual vines, ensuring all roots are removed Cut stems (spring – summer) and paste with herbicide gel Large infestations can be foliar sprayed (spring – summer). Ensure complete leaf coverage is low. This method is most suitable for larger vines where the level of risk to desirable plants is low.\nCAUTION: When using any herbicide or pesticide, PLEASE READ THE LABEL THOROUGHLY to ensure that all instructions and directions for the purchase, use and storage of the product, are followed and adhered to. Read more on pest control advice, information and regulations.", "pred_label": "__label__POS", "pred_score_pos": 0.7889318466186523} +{"content": "Sep 1, 2021\nA teacher at Notre Dame High School in Sherman Oaks, California, was\narrested on suspicion of child molestation last week, according to a police announcement. The Los Angeles Police Department is seeking the public’s assistance in the investigation, asking any additional victims to come forward.\nA LAPD news release confirmed that Jason Bissell, a teacher at the private Catholic school, was taken into custody on August 26 following reports of “\nalleged ongoing inappropriate sexual conduct.”\nBissell, 52, who reportedly remains in custody, has been teaching at Notre Dame since 2006. He was booked at the Van Nuys Community Police Station jail, and subsequently assigned to the Twin Towers Correctional Facility. His bail was set at $710,000, and a court appearance has been set for October 12.\nAuthorities did not release additional details related to the allegations against Bissell, but the LAPD’s Abused Child Section did request the public’s help on Tuesday in an effort to locate potential victims.\nAs the investigation is ongoing, anyone with information on Bissell is urged to contact LAPD Juvenile Division Detectives at 818-374-5415 (or 877-527-3247 during non-business hours/on weekends). Those wishing to remain anonymous can contact\nL.A. Regional Crime Stoppers at 800-222-8477, or submit a tip online at lacrimestoppers.org.\nA recently passed law known as California AB 218 allows survivors of childhood sexual abuse an unprecedented opportunity at obtaining justice. Regardless of when the crime occurred, survivors may now file a civil lawsuit against their abuser (whether an individual or institution) seeking financial compensation. AB 218’s three-year “\nlookback window” clause temporarily tolls (pauses) the statute of limitations on child sexual abuse crimes, allowing every survivor an opportunity at justice through the civil courts.\nHowever, this clause is only in effect until December 31, 2022. After that date, the standard statute of limitations will resume, and survivors who have not filed a claim may be left without legal recourse. Accordingly, we encourage all survivors to come forward as soon as possible and file claims to ensure their chance at justice is not stymied.\nAdditionally, AB 218’s treble damages clause allows the courts the latitude to award triple damages amounts to survivors of childhood sexual abuse in cases where a cover-up is proven. For example, if a survivor was awarded a $10 million settlement and a cover-up was proven, the courts could actually issue that individual $30 million as a final damages award. The treble damages clause is intended to severely punish bad actors who engaged in systemic and widespread child sexual abuse through cover-ups.\nDordulian Law Group (DLG) pursues treble damages in all applicable\nchildhood sexual abuse cases.\nSurvivors of childhood sexual abuse have the option to pursue justice through a civil lawsuit that recovers maximum financial compensation. To file a claim, contact a member of DLG’s Sex Crimes Division team today for a free consultation. We’ll review the facts of your case (at DLG, we believe survivors), launch a thorough investigation led by our in-house Chief Investigator and retired LAPD Abused Child Unit detective, Moses Castillo, and develop an aggressive but precise legal strategy based on our decades of experience and proven results.\nAt DLG, we’re led by a former sex crimes prosecutor and Deputy District Attorney for Los Angeles County, Sam Dordulian. Dordulian founded DLG’s Sex Crimes Division to be the leading and top-rated outfit it is today, providing survivors of childhood sexual abuse with a unique and all-encompassing form of expert legal representation.\nDLG’s\nSAJE Team (Sexual Abuse Justice Experts) offers survivors a four-tiered network of support and resources:\nSurvivors who choose DLG have peace of mind and confidence knowing that their claims are in the absolute best hands. Our experience and proven results are evidence of the level of dedication and personalized attention we offer each and every survivor client:\nContact us today online or by phone at 818-322-4056 for a free and no obligation consultation with one of our\nSAJE Team members. We’re ready to serve as your dedicated legal advocate, and to fight to help you secure justice through maximum financial compensation.\nAt DLG, we believe everyone should have access to the absolute best legal representation available. That’s why we offer our\nNo Win/No Fee Guarantee, ensuring you never have to worry about any upfront costs or out-of-pocket expenses. With DLG, you don’t pay a penny until we recover a maximum financial damages award on your behalf.\nReach out to a dedicated and trusted member of our team today to discuss your claim and to learn more about why DLG’s team is comprised of the best sexual abuse attorneys in California.\nOur law firm in Glendale, CA advocates for victims of sexual assault, injury, employment disputes, and personal injury concerns.", "pred_label": "__label__POS", "pred_score_pos": 0.6175450086593628} +{"content": "An EPIC Talk with NAZIMA KADIR, October AnthropologistTHIS EVENT HAS BEEN POSTPONED—WE WILL ANNOUNCE A NEW DATE SOON!(originally scheduled for 10 November)OverviewIn commercial environments, there is often a lack of understanding of research ethics. As a result, navigating the world of ethics can often be stressful and challenging for commercial researchers. In this session, Nazima Kadir will:provide a history of ethical research and its relevance to commercial researchers who interact with peopleexplain the concept of informed consent and how to practice it throughout the research processprovide an opportunity for participants to evaluate different situations that arise in commercial research and evaluate them using ethical research frameworksNazima's approach to ethical research is based on her experience conducting sensitive and long-term research among vulnerable populations, undergoing rigorous human subjects reviews, and using the ethical guidelines of the American Anthropological Association and...\nWe've worked hard to eliminate cookies that don't serve you and our nonprofit community. By clicking \"Accept\" you consent to our use of all cookies. To manage analytics and social cookies, click \"Settings.\"\nThis website uses cookies to support your experience navigating and using our resources, and we've worked hard to eliminate those that don't serve you or our nonprofit community. You can read our full Privacy Policy, Terms & Conditions, and contact us with questions.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nThese cookies are used by social media links that you can use to share our content easily. If you use these links on our site, data will be exchanged with the platform on which you’re sharing (e.g., Twitter, LinkedIn)", "pred_label": "__label__POS", "pred_score_pos": 0.967490553855896} +{"content": "The large-scale deployment of cross-border CO2 transport and storage infrastructure is crucial for the EU to reach its 2050 climate target. To this end, all modes of CO2 transport – pipeline, ship, barge, truck, train – and CO2 storage should be included in the revised TEN-E regulation, writes Dr Graeme Sweeney.\nDr Graeme Sweeney is the Chairman of the Zero Emissions Platform (ZEP) – A European Technology and Innovation Platform under the European Commission’s SET-Plan and technical adviser to the EU on deploying Carbon Capture and Storage and Carbon Capture and Utilisation.\nTo reach climate-neutrality by 2050, it will be necessary to make strategic investment decisions that will significantly transform energy-intensive industries. This will include sectors such as cement, lime, steel and chemicals, which are at the core of Europe’s economy, producing and manufacturing products central to how we live.\nCarbon Capture and Storage (CCS) will be critical in the industrial transition towards net-zero greenhouse gas emissions. For these sectors, pathways including CCS represent the lowest cost route to decarbonisation whilst maintaining industrial activity and preserving and creating jobs.\nThe revision of the Trans-European Energy Infrastructure (TEN-E) Regulation ensures that the EU’s energy infrastructure policy is consistent and aligned to reach climate neutrality by 2050, as outlined in the European Climate Law.\nSince the Commission presented its proposal for a revised TEN-E regulation in December 2020, the Council adopted a general approach in June, while the European Parliament’s Industry, Research and Energy (ITRE) Committee is expected to vote on their final report on 27 September, for a later vote in the Parliament’s Plenary.\nInvesting in shared, cross-border CO2 transport and storage infrastructure is the ultimate European project. It represents a strategic, instrumental policy to maintain Europe’s welfare and a future-proof society for a climate-neutral economy.\nDeploying CO2 infrastructure would allow industrial emitters from all corners of Europe to connect to permanent geological storage, where CO2 would be safely stored without re-entering the atmosphere, thus mitigating climate change.\nAs the Commission has stated in the EU Taxonomy and reiterated in the revised EU ETS Directive – part of the Fit for 55 package – it is expected that the transport of CO2 will be operated by pipeline and ship.\nFor upcoming CCS projects that will rely on transporting CO2 by ship, recognising CO2 transport by ship in the TEN-E Regulation will be vital. Thus, this outcome should be reflected across all EU legislation.\nAs a vital aspect of CO2 infrastructure and CCS projects, CO2 storage should also be included in the revised TEN-E regulation. It plays a crucial role in delivering real climate change mitigation and therefore merits funding as part of CO2 infrastructure. Enabling secure access to storage sites increases the likelihood that more industrial CO2 emitters will invest in projects, thus reducing the costs of capture technologies.\nWith an ever-increasing number of market-ready CCS projects in Europe moving towards becoming operational within this decade, there is a strong need to support this progress. Additionally, the role of CCS as an essential enabler for a cost-efficient and just transition to net-zero must be considered.\nIt is crucial to secure political support for the five candidate Projects of Common Interest (PCIs) on cross-border CO2 infrastructure, which will become operational before 2025. A long-term policy framework providing a degree of predictability for investments should be a priority for European policymakers.\nCO2 infrastructure can also play an instrumental role in facilitating a clean hydrogen economy, delivering early, large-scale volumes of low-carbon hydrogen produced from reformed natural gas with CCS.\nCO2 infrastructure, CCS, and hydrogen should be at the core of a genuinely integrated, climate-neutral energy system. Low-carbon hydrogen can enable many energy-intensive industries to decarbonise, especially those relying on high-temperature operations, such as steel production. Initially, an EU hydrogen economy will depend on large volumes of low-carbon hydrogen, requiring the development of cross-border CO2 infrastructure.\nBased on the Commission’s proposed TEN-E regulation in December 2020, the Parliament and the Council are now finalising their positions.\nAhead of the ITRE Committee vote regarding the TEN-E regulation, it is crucial to consider the vital role of CO2 transport and storage infrastructure for the EU to reach its 2030 and 2050 targets. This includes helping to drive the decarbonisation of energy-intensive and difficult-to-decarbonise industries in Europe – and for upcoming CCS projects in Europe.\nIt is imperative that all modalities of CO2 transport and CO2 storage are included in the revised regulation.\n[Edited by Alice Taylor]", "pred_label": "__label__POS", "pred_score_pos": 0.9594478607177734} +{"content": "Abstract\nThe estrogens are responsible for many biologic process in ovaries. Their production and secretion contribute significantly for maintenance of women physiology. The 17 ²-estradiol (E2) is the more active form of natural estrogen. To perform its biological functions depends on estrogen receptor activation (ER± ou ²). Additionally, E2 controls the PI3K/AKT signaling pathway due to increased…", "pred_label": "__label__POS", "pred_score_pos": 1.0000052452087402} +{"content": "I’ve learned so much already on this DFP journey. One topic I didn’t anticipate learning so much about was accessibility. While I hadn’t heard of \"508 compliance” before my fellowship began, it quickly became a regular component of my vocabulary. It’s a term used within the USFWS and across the federal government often. It refers to the adhesion to federal laws and policies which ensure content generated by federal agencies (whether written, verbal, or audio) is accessible to all people, regardless of ability. Before my time here, I never considered things such as how inaccessible emojis can be for the visually impaired!\nI’m really impressed by the genuine dedication to human rights within the Service. On a number of occasions, I’ve witnessed staff proactively advocate for accessible content, even if they themselves did not require it. Their consciousness of the subject is admirable and really says a lot about their character.\nUSFWS is a home for people who care.\nOn one occasion, I shared a document with a team of digital media strategists. Several people indicated to me that my document was not (yet) 508 compliant. One was even willing to take time out of their day to meet with me one-on-one and walk me through the process of modifying it. This document was meant for internal communications, meaning these employees were advocating for their fellow employees. A real family!\nThis zeal isn’t exclusive to disability rights. In this fellowship, I’ve met a number of people who are extremely passionate about diversity, equity, and inclusion (DEI) on a grander scale. USFWS employees are incredibly sensitive to the experiences and perceptions of minorities and disenfranchised groups. One employee opened my eyes to the negative undertones that could be perceived from a “master list” I was sharing. I quickly renamed it a “database” and stopped using the other term entirely.\nThere are several internal DEI initiatives in the works focused on things such as diversity in recruitment, expanding access to nature, and developing digital content that connects with diverse audiences in a meaningful way. These are topics that are near and dear to my heart. Conservation has historically been a “white-washed” field, stemming from past colonialist approaches to protecting nature. It benefits us all (including Mother Nature!) when we invite diverse voices to the table. Today’s USFWS seeks opportunities to do just that.\nAcceptance, mutual respect, and inclusion are not just job requirements for Service employees. It’s a way of life, a part of who they are 24/7. The USFWS doesn’t only recruit good, caring people; it creates an environment where employees continually grow and strive to become better versions of themselves.\nPhoto Credit: Mara Koenig/USFWS Alt text for the visually impaired: A diverse mix of people fishing along a dock. At the front is a Black man standing beside another Black man in a wheelchair, both holding fishing poles. Agency: U.S. Fish and Wildlife Service Program: Directorate Fellows Program Location: USFS Headquarters, Washington Office", "pred_label": "__label__POS", "pred_score_pos": 0.5482176542282104} +{"content": "@weight> @weight> Empowering the Remote Workforce@weight> Download form\nPlease fill in your details to download the magazine\nIHS Markit Engineering Intelligence Review Summer 2021@weight>\nAs global economies, supply chains, and workforces continue to adjust to a post-pandemic world, one thing is clear: there is now an unmistakable opportunity to accelerate the adoption of digitization, advanced technologies, and real-time access to information and data.\nFor knowledge workers, including the engineering community, the persistent challenge resides with timely access to accurate information that is increasingly complex and growing exponentially. The added difficulties of moving to a \"suddenly remote\" workforce presented a new wrinkle, but at the same time, uncovered real advantages.\nThis issue of Engineering Intelligence Review shows us how technology-including AI, natural language processing, and platforms such as IHS Markit Engineering Workbench and Goldfire- continue to serve as a critical foundation for more optimized and improved communication, collaboration, and compliance as we adapt to the challenges of a post-pandemic world while equipping engineering professionals with the tools they need to work better and more efficiently.", "pred_label": "__label__POS", "pred_score_pos": 0.8683730959892273} +{"content": "In the courtroom, I was a high-powered attorney who spoke up loudly on behalf of others. I had no trouble raising my voice or being seen in my crisp pantsuit. I knew I was in control. Authority was granted to me by the State, which meant people\nhad to listen to me. I knew I was intelligent. It had won me praise my entire life. In this society, we reward the intellect and treat it like the holy grail.\nEveryone saw me as confident, determined, and ambitious. In some ways, they were right. I pursued my goals with passion and conviction. But they didn’t see me beyond the roles I occupied. The truth is, neither did I.\nMy identity was contingent on the eyes of others. How they viewed me was how I viewed me. Without a role to give me definition, I didn’t know who I was. How did that translate in personal relationships?\nAfter leaving the legal profession, I landed in a relationship while touring Europe. He was sweet, charming, and a good-looking Frenchman. No longer did I have a job – a home – regular income – or status of any sort. I relied solely on my own existence. There was nothing to “justify” me anymore.\nWhen my new partner began to make subtle accusations or call me names, I soaked them right up (just like I soaked up all the praise I’d received for years). After all, I was so used to taking in the opinions of others and making them my own. I didn’t know how to separate what\nhe thought of me from what I thought of me. Sound familiar?\nAll the power, confidence, and prestige I experienced as an attorney was suddenly gone. That’s because\nI wasn’t powerful; my position granted me power. The only power I had ever known was external.\nNo one ever taught me how to source power from within. It hasn’t quite made it into the middle school curriculum.\nMaybe you, too, know what it’s like to feel crippled by self-doubt, inner anxiety, and feelings of unworthiness – despite a hotshot, confident exterior?\nI constantly asked myself, “Is he right? Am I bad?”\nParts of me were engulfed in shame.\nI told myself, “I’m not good enough.” “Something is wrong with me.” “How can I fix myself – make myself better?”\nIn response to his accusations, I simply hung my head. How could I defend myself when I gave\nhim the power to determine how lovable I was?\nIt left me silenced. Afraid. Focused on pleasing my partner – making him happy – hoping and waiting for those moments when I was his Queen.\nOver time, I grew smaller and smaller. Curled inward on myself, afraid to be me. Afraid he wouldn’t like what he saw underneath the façade of coolness. Afraid of losing his love.\nHow can we expose ourselves – be seen – and express ourselves – be heard – if we doubt our inherent worthiness?\nIt’s common now to hear people spouting off phrases like, “Be seen!” “Make yourself visible!” “Expose yourself!”\nBut we cannot do this until we:\n(1) Confront the fears and beliefs that keep us in hiding;\n(2) Access our own inner wisdom – by connecting with our body, and\n(3) Learn how to see ourselves through our own eyes, not through the eyes of others.\nDoing so grants us True Power. It doesn’t need anyone or anything to give us permission. It is not granted by anyone or anything outside of us. It is full, embodied, recognition of who you truly are.\nMost of us have no idea how to access this kind of power. I didn’t, despite all the “powerful” positions I occupied. Because it doesn’t live in the head, not does it have anything to do with a position of dominance, hierarchy, or control over others. It comes only from connecting deeply with the source of love that lies at the core of our very own being.\nHad I been able to access this power in my relationship, I wouldn’t have internalized his words or put myself beneath him. I would have radiated my light outward – shining its rays effortlessly – capable of choosing what to let in and what to keep out. I made him my authority by giving him the power to define me or determine my worthiness. Oh, how forgetful I was.\nOnce I began to access the wisdom of my body – and return to my feminine roots – I naturally shielded myself from my partner’s attacks. Eventually, I left because I could no longer bow down to another. I had tasted the sweetness of my own power. The ecstasy of full-bodied freedom began to flow through my every vein.\nI want this for you too. I want you to become your own authority. I want you to remember the power of your choice. I want you to embody your divinity.\nTake the forbidden fruit. Join me in a revolution to redefine the way we love by Radically Reclaiming your Self. Schedule a free Soul Freedom Breakthrough Session here to see what’s blocking your fullest expression in relationships.\nSign up below to receive 5 Powerful Questions to Ask Yourself: Is it True Love? They’ll be delivered straight to your inbox, along with a series of 5 short videos to help you distinguish between true love and the false forms of love we have been conditioned to accept.", "pred_label": "__label__POS", "pred_score_pos": 0.5915515422821045} +{"content": "Recent scholarship has uncovered laïcité's Protestant sources by focusing attention on its late nineteenth- and early twentieth-century advocates. This article argues that the intellectual sources of laïcité stretch further back than this, namely to the writings of Jean-Jacques Rousseau (1712-1778) and Benjamin Constant (1767-1830). These two thinkers are rarely seen as allies. However, an examination of their views on religion reveals a surprising complicity, attributable in large part to their liberal Protestant sympathies. Benjamin Constant was well placed to understand and appreciate Rousseau's \"Profession of Faith of the Savoyard Vicar\" and his chapter \"On Civil Religion\" in the Social Contract. Moreover, Constant had observed firsthand the distortion of Rousseau's views by the French revolutionaries. This essay shows that Constant's writings on religion were those of a disciple of Rousseau, who wished to clarify and disseminate ideas that would prove foundational for the modern notion of laïcité.", "pred_label": "__label__POS", "pred_score_pos": 0.9638011455535889} +{"content": "Every time the FJA gains a member, our justice community grows stronger. Being a part of the FJA family means joining…\nParalegals and legal assistants are largely considered the backbone of every law firm and fulfill critical roles within the legal community. From conducting research, drafting pleadings, contracts, and more, these legal professionals are integral in preparing attorneys for trial. Without the support and critical functions that they provide to law practices, it’s safe to say that many individuals and consumers would not see justice.\nThis October 23, 2021, is National Paralegal Day, an annual event that celebrates the mountain of legal work paralegals and legal assistants tackle each year to help law firms and their clients succeed.\nBefore we recognize and celebrate the profession as it is today, let’s take a brief look back at its history.\nOverall, the paralegal and legal assistant profession is rather young and its origins can be traced back to the late 1960s (however, the first “lawyers” can be traced back to Ancient Athens.) The profession was created when Congress, law firms, local bar associations, and the American Bar Association recognized that issues with access to legal services and more complex laws necessitated action. The concept was rooted in the goal of offering greater access to justice, and that educated non-lawyers could help fill the gap.\nOver time, these early non-lawyers became experienced legal secretaries who had acquired advanced on-the-job knowledge and training and began performing many complex legal tasks. By 1967, the American Bar Association had issued a formal ethics opinion that outlined the role of legal professionals and helped to solidify and expand their function and prominence within law firms.\nSince 1967, the profession has only continued to grow as more individuals have considered a career as a paralegal or legal assistant. The U.S. Bureau of Labor Statistics indicates that in 2020 there were 345,000 paralegal and legal assistant jobs in the United States, a figure that in the next ten years is expected to expand by 12 percent.\nWith the establishment and expansion of legal professionals, groups like the FJA have focused on creating opportunities for individuals to connect with their peers, share resources, and expand on ideas within the profession.\n“Being a PI paralegal comes with great responsibility. We are tasked with helping clients obtain justice after being harmed by negligence and our reward at the end of a case is knowing that our hard work made a significant impact in their lives. Having a support system like FJA’s Paralegal and Legal Assistant Section is key to making us shine as paralegals! We receive important case law updates, have access to listservs to ask questions and share information and, most importantly, we are connected with a group of paralegals who understand the importance of the work we do.” – Carol Goraczko, Florida Registered Paralegal, Stewart Tilghman Fox Bianchi & Cain P.A.\nFJA’s Paralegal and Legal Assistant Section provides support for professionals located across Florida and connects members with resources to learn, excel, and grow in their careers now and into the future. Some of the benefits of membership include access to networking opportunities, exclusive email discussion groups, CLE webinars and events, and career resources.\n“The Florida Justice Association allows me to be a more valuable resource for my office and our team. The Paralegal and Legal Assistants section specifically provides me with the opportunity to learn, network, and share with my fellow paralegals and legal assistants to better serve our clients.” – Meg Hartnett, Florida Registered Paralegal, Cohen Milstein Sellers & Toll PLLC\nAlthough the FJA supports its members through a series of virtual resources and offerings, our in-person exclusive events for paralegals and legal assistants are by far the most popular. From the Civil Litigation for Paralegals and Legal Assistants Seminar at Annual Convention to Section networking breakfasts held throughout the state, members are active in sharing stories, learning from one another, and overall, deepening their love for the field.\nIn celebration of National Paralegal Day, the FJA Paralegal and Legal Assistant Section will be holding a Regional breakfast on Friday, October 22nd, 2021 at the Orange County Bar Association, Grand Cypress Room located at 880 North Orange Avenue in Orlando. This event will include a networking breakfast at 8:30, a program at 9 a.m., and free CLE credits. Mark R. Lippman, Esq. Lippman Law Offices, P.A. will be speaking on The Eviction Moratorium, and all paralegal and legal assistant members are invited to attend (guests welcome!). RSVP to attend here.\nAs we celebrate National Paralegal Day this year, let us be reminded that paralegals and legal assistants are a growing force within the legal field. We hope you will take a moment to sincerely thank these hardworking individuals who are responsible gatekeepers in the legal profession. They are essential in strengthening and upholding Florida’s civil justice system and protecting the rights of Florida’s citizens and consumers!", "pred_label": "__label__POS", "pred_score_pos": 0.7839577198028564} +{"content": "BACKGROUND\nEarly initiation of breast cancer screening is recommended for high-risk women, including survivors of childhood cancer treated with chest radiation. Recent studies suggest that female survivors of childhood leukemia or sarcoma treated without chest radiation are also at elevated early onset breast cancer risk. However, the potential clinical benefits and cost-effectiveness of early breast cancer screening among these women are uncertain.\nMETHODS\nUsing data from the Childhood Cancer Survivor Study, we adapted two Cancer Intervention and Surveillance Modeling Network (CISNET) breast cancer simulation models to reflect the elevated risks of breast cancer and competing mortality among leukemia and sarcoma survivors. Costs and utility weights were based on published studies and databases. Outcomes included breast cancer deaths averted, false-positive-screening results, benign biopsies, and incremental cost-effectiveness ratios (ICERs).\nRESULTS\nIn the absence of screening, the lifetime risk of dying from breast cancer among survivors was 6.8% to 7.0% across models. Early initiation of annual mammography with MRI screening between ages 25 and 40 would avert 52.6% to 64.3% of breast cancer deaths. When costs and quality of life impacts were considered, screening starting at age 40 was the only strategy with an ICER below the $100,000 per quality-adjusted life-year (QALY) gained cost-effectiveness threshold ($27,680 to $44,380 per QALY gained across models).\nCONCLUSIONS\nAmong survivors of childhood leukemia or sarcoma, early initiation of breast cancer screening at age 40 may reduce breast cancer deaths by half and is cost-effective. These findings could help inform screening guidelines for survivors treated without chest radiation.", "pred_label": "__label__POS", "pred_score_pos": 0.9314378499984741} +{"content": "UBC Theses and Dissertations Transmission of antimicrobial-resistant Campylobacter in agri-food systems Ma, Luyao Abstract\nAntimicrobial-resistant Campylobacter has been regarded as a high priority of public health concern worldwide. This microbe asymptomatically resides in the intestinal tract of animals and may transmit to humans through the consumption of contaminated animal products. It is not fully understood how Campylobacter develops and spreads antimicrobial resistance (AMR) in agri-food systems. This knowledge gap is partially due to a lack of rapid detection methods, inefficient data integration in current surveillance programs, rapid evolution of AMR variants, and insufficient studies in AMR gene transfer. This dissertation focused on addressing the aforementioned problems to better tackle the global AMR crisis. A microfluidic device was developed to identify Campylobacter, with 100% specificity and detection limits down to 10² CFU/mL in milk and 10⁴ CFU/25 g in chicken meat. On-chip antimicrobial susceptibility testing (AST) showed a good agreement (>90%) with the conventional culture-based method. This miniaturized device enabled on-site detection, consumed ~99% fewer reagents, and saved >50% of analysis time. This microfluidic device was further integrated into an internet of things (IoT)-based AMR surveillance program. A machine learning algorithm was employed for classifying on-chip AST results, providing 99.5% accuracy in determining Campylobacter AMR profiles. Both spatial and temporal AMR trends were uploaded to a cloud database for real-time data integration and presentation. Alternatively, Raman spectroscopy and chemometrics reduced the analysis time of AST to 5 h with acceptable accuracy. Raman spectroscopy-based approach deciphered distinct phenotypic responses of antimicrobial-susceptible and resistant Campylobacter to antibiotics. The spread of AMR genes in Campylobacter biofilms was 17-fold more efficient than planktonic cells, which was commonly used as an AMR evolution model. Campylobacter might develop AMR more frequently in the environment than previously expected. When co-cultivating with other foodborne pathogens, Campylobacter showed distinct gene transfer trends, ranging from 3.5×10⁻⁸ in Escherichia coli-C. jejuni biofilms to no detectable transmission in Salmonella-C. jejuni biofilms. This dissertation provides the technique and knowledge to monitor the prevalence of Campylobacter AMR in agri-food systems.\nItem Media Item Citations and Data License\nAttribution-NonCommercial-NoDerivatives 4.0 International", "pred_label": "__label__POS", "pred_score_pos": 0.8295374512672424} +{"content": "Tenosynovitis of one or more flexor tendons of the hand (mean 3.1 tendons per patient) was noted in 55% of 100 patients with rheumatoid arthritis (RA) examined periodically during a mean period of 5 years. The third flexor tendon was involved most frequently (71% of patients), followed by the second (62%), fourth (53%), fifth (27%), and first (13%). Patients with flexor tendonitis (FT) had a significantly higher prevalence of rheumatoid nodules (56% vs 33%), carpal tunnel syndrome (47% vs 13%), wrist extensor tenosynovitis (47% vs 9%), and elbow epicondylitis (22% vs 7%) than patients without FT. Dupuytren's contracture, DeQuervain's tenovaginitis, flexor carpi radialis and ulnaris tendonitis, and Achilles tendonitis were found exclusively in patients with FT. A control group of 50 non-RA patients with FT had statistically fewer diseased tendons per patient (mean 1.5) and a different digital distribution, the thumb being affected more frequently (P less than 0.05) than in RA patients.", "pred_label": "__label__POS", "pred_score_pos": 0.9281419515609741} +{"content": "The Orange County Health Department is advising residents that if they worked or attended the New York Renaissance Faire located at 600 Route 17A, Tuxedo Park, on either Saturday, Sept. 4, or Monday, Sept. 6, they may have been exposed to COVID-19.\nHealth Commissioner Dr. Irina Gelman recommends that if you or your child were there, to monitor for symptoms of COVID-19, which may include but are not limited to: fever, chills, shortness of breath or difficulty breathing, fatigue, muscle or body aches, headache, new loss of taste or smell, sore throat, congestion, or runny nose, nausea or vomiting, diarrhea. Anyone experiencing symptoms indicative of COVID-19 should contact their medical provider to discuss a plan of care.\nGelman advised residents to consider any public site in Orange County as a potential site of COVID-19 exposure, due to a persistent increase in newly diagnosed COVID-19 cases throughout the county.\nAccording to Gelman, the best way to prevent the spread of COVID-19, continues to be adhering to proper safety measures such as wearing your mask, vaccination, avoiding unnecessary contact with others, as well as practicing basic personal hygiene. This includes washing your hands frequently and thoroughly, refraining from touching your face and avoiding unnecessary contact with others.\nShould you feel ill, contact your healthcare provider.", "pred_label": "__label__POS", "pred_score_pos": 0.7686776518821716} +{"content": "The quest to be fit, healthy, and in good shape could cause significant nutritional changes in your life. You start changing diet and reducing calorie intake to achieve more results. However, fueling your body for fitness is more than eating good food or changing your previous diet. It involves eating the right food in the…", "pred_label": "__label__POS", "pred_score_pos": 0.9938411712646484} +{"content": "Data downloads from the Center for Hydrometeorology and Remote Sensing (CHRS) of the University of California, Irvine’s precipitation products in 2021 have exceeded those of any previous year…and August has not yet arrived. This includes various quasi-global, satellite-driven real-time and historical products from the PERSIANN (Precipitation Estimation from Remotely Sensed Information Using Artificial Neural Networks) family—several of which were developed and maintained with support from UNESCO and ICIWaRM (e.g. iRain, RainSphere and PERSIANN Dynamic Infrared Rain Rate (PDIR-Now).\nSince the creation of CHRS’s homepage and iRain on January 1st, 2010, CHRS web systems have been visited by an average of 256 people a day. The frequency of visitors has increased considerably since April 14th, 2014, and March 30th, 2016, when RainSphere and CHRS Data Portal first went online, respectively. Over the last 10 years, data downloads have been increasing at an average of 70% per year.\nResidents of over 200 countries have visited CHRS web pages, including over 40 African countries. African countries are responsible for over 14,000 visits to the real-time iRain site, with Southern African countries (Namibia, South Africa, Angola and Botswana) leading the way. They are also responsible for over 13,000 visits to the data portal, combining real-time and historical data downloads, with Nigeria, Morocco, Egypt and South Africa at over 1000 each, followed by Uganda, Kenya, Sudan, Cameroon, Angola, Ghana and Algeria, with 500-800 downloads each. African visits total almost 1/10 of the total visits outside of the United States (about 140,000 since 2016).\nOver this period, CHRS scientists, in partnership with UNESCO-IHP and often ICIWaRM, have hosted workshops on satellite precipitation measurements in Lebanon, the Islamic Republic of Iran, South Africa, Uganda, the Kingdom of Saudi Arabia, two in Italy, and three in Thailand.", "pred_label": "__label__POS", "pred_score_pos": 0.8881333470344543} +{"content": "In clinical trials, a comparator drug is often required to study the efficacy of a new treatment relative to a drug that is already on the market.\nThe comparator study is used to compare the effectiveness of the investigational product to the existing drug.\n9 Additionally, clinical trial sponsors are also required to source and distribute other medications and supplies along with comparators.", "pred_label": "__label__POS", "pred_score_pos": 0.5031076073646545} +{"content": "A\npulvinus (pl. pulvini) is a joint-like thickening at the base of a plant leaf or leaflet that facilitates growth-independent (nyctinastic and thigmonastic) movement. Pulvini are common in members of the bean family Fabaceae (Leguminosae) and the prayer plant family Marantaceae.\nPulvini may be present at the base or apex of the petiole or where the leaflets of a compound leaf are inserted into the rachis. They consist of a core of vascular tissue within a flexible, bulky cylinder of thin-walled parenchyma cells. A pulvinus is also sometimes called a geniculum.\nPulvinar movement is caused by changes in turgor pressure leading to a contraction or expansion of the parenchyma tissue. The response is initiated when sucrose is unloaded from the phloem into the apoplast. The increased sugar concentration in the apoplast decreases the water potential and triggers the efflux of potassium ions from the surrounding cells. This is followed by an efflux of water, resulting in a sudden change of turgor pressure in the cells of the pulvinus. The process is similar to the mechanism of stomatal closure.\nดูเป็นตัวอย่าง (230826492+40285+39_<6|<_<3747*<+38&+#7&8#9&+9~=+3==91+&0=%9=39394859025)+(309275937<^>[77+&[email protected]&82947&-29590%8303=92072959401)", "pred_label": "__label__POS", "pred_score_pos": 0.8612585067749023} +{"content": "In 1992, through his “Agenda for Peace”, UN General Secretary Boutros Ghali called upon UN member states to train and provide civil professionals for peace missions, stating that such individuals need comprehensive training before deployment. ASPR with the support of the Austrian Federal Government has responded to this call and established a training concept called International Civilian Peace Keeping and Peace Building Training Program (IPT).\nThe training for civilian peace keeping and peace-building involves a two-week foundation training preparing candidates for the situation in conflict areas in general, as well as a function-oriented two-week specialisation course qualifying candidates for a specific task in terms of peace keeping/building activities. The course is designed to develop a conflict sensitive behaviour in conflict areas, a behaviour which recognises the specific needs of the particular nation/ethnic group, avoids negative impacts („Do no harm“), takes responsibility through the people („Ownership“) and focuses on long-term impacts of the mission (sustainability). The courses are meant to help achieve a better understanding and cooperation between various governmental and non-governmental players and contribute to various focal working points and activities such as peace keeping, development cooperation and humanitarian aid.", "pred_label": "__label__POS", "pred_score_pos": 0.5039017200469971} +{"content": "Grapevines & Leadership\nNature offers an accessible model for leadership, and patiently awaits, ready to share its approach with us.\nThis program is offered using two approaches: open to individuals who will join other participants they have yet to meet and open to groups or teams within a company or organization.\nWhat to Expect:\nThis program delivers a much needed break\nfrom the fast-paced world of business To become more aware of the world of nature, and to learn how tending to grapevines – from when they are first planted to each year’s harvest – offers guidance and expertise to enhance your leadership approach. What You Will Gain: A renewed appreciation for nature and its lessons Tangible actions you can take to become a more effective leader while strengthening your team A keen eye for recognizing additional leadership tips that nature has available to you\nSide Effects: When spending time appreciating and learning from nature, it can reduce stress and boost happiness, while rejuvenating the body, mind, and spirit.\nReturn to Small Group Retreat.", "pred_label": "__label__POS", "pred_score_pos": 0.9874227046966553} +{"content": "Early learning teachers think about outcomes in broad terms and with programming intent rather than treating them as ‘checklists’. Curriculum frameworks are intended to be tools that support early learning teachers in examining the visual and potential types of learning occurring when children engage in various types of experiences. Rather than assess the child, consider outcomes to assess the experience. Let’s go back to the stick, stone and pinecone experience presented earlier. Since Honey and Richard work in Ontario, they referred to that province’s framework to determine which outcomes were met. They found many connections since the experience was so multi-faceted. They settled on two that they would consider and build upon in future learning experiences: questioning and observing (Ontario Ministry of Education, 2014).\nRichard and Honey are careful not to focus too narrowly on these outcomes. They added them to their analysis of the experience that they recorded. They were inspired by dialoguing about questioning and observing and decided to bring magnifying glasses outdoors to examine pine cones even more closely and to encourage questions and further experimentation. Environments that support children’s development are those that provide materials, time and opportunities for children to explore and discover, rather than environments that are focused on achieving specific learning outcomes.\nIdeally, early learning teachers support children in having the freedom to be active constructors of their learning through play and experiential learning. When early learning teachers assume that young children have the abilities to determine the types of play to support their learning needs, the learning environment is more likely to focus on the process of play rather than the completion of a product or production of items that exhibit defined learning outcomes. Children learn best in spaces where they are given the freedom to try new ideas, combine new ideas with current knowledge and experiences, and rethink how they did things and what they may do differently to accommodate their new discoveries (Dietze & Kashin, 2012). This approach emulates the United Nations Rights of the Child (1991) that indicates children value freedom from structure, making choices and having time to themselves. Controlled environments that focus on children achieving defined learning outcomes are generally based on the shallow interpretations of children’s interests rather than supporting them in deeper engagement with their funds of knowledge, skills, and dispositions. As learners, children are encouraged to develop strategic thinking processes that have learning as a goal. This involves creating an environment where children make the decision to engage and persist with learning and to develop skills to be a collaborative and an autonomous learner. Children require environments that allow them to assume ownership for their own thoughts, processes and actions in their learning. With intentional early learning, teachers can provide experiences that support children in all critical learning areas including the spirit. Supporting a mind, body and spirit connection is attainable in the outdoor learning environment!", "pred_label": "__label__POS", "pred_score_pos": 0.7265369296073914} +{"content": "A stroke occurs when part of your brain is unable to get the blood and oxygen it needs. It can be a scary time for families and loved ones. Oftentimes, people don’t understand what happens to them during a stroke. Depending on what type of stroke a person has, different things are likely to happen.\nTransient Ischemic Attack\nDuring a transient ischemic attack (TIA), individuals will often show many of the symptoms of a stroke. They may have slurring speech, drooping facial muscles, or lose the use of 1 side of the body. However, after a short period of time, the effects of a transient ischemic attack will disappear.\nDuring a TIA, a blood clot forms in the person’s brain, causing temporary arousal of symptoms. However, the blood clot quickly becomes unstuck, leading to a relief of symptoms. These are frequently known as “mini-strokes.” They may warn of a more significant stroke coming.\nIschemic Stroke\nAn ischemic stroke is when the presence of a blood clot causes loss of blood flow to the part of a brain. During an ischemic stroke, the blockage causes blood loss to that particular area which ultimately leads to the death of brain tissue.\nUnlike a TIA, an ischemic stroke leads to more permanent or pervasive symptoms. Individuals who undergo an ischemic stroke may spend days, weeks, or months in therapy to regain their abilities. They may be unable to regain those abilities at all.\nHemorrhagic Stroke\nA hemorrhagic stroke is similar to an ischemic stroke as it causes permanent or pervasive damage. However, the cause of a hemorrhagic stroke is different.\nDuring a hemorrhagic stroke, a blood vessel or brain breaks or ruptures, causing a brain bleed. As a result of the damage, blood is able to leak into the surrounding blood tissue.\nThe hemorrhage stops blood from getting to essential parts of the brain past the break. This may lead to brain tissue’s permanent and irreversible death beyond the bleed, causing speech, movement, or even cognition changes. Through treatment, a person may be able to regain functioning in one or all of these areas. Others will have permanent symptoms.", "pred_label": "__label__POS", "pred_score_pos": 0.9858746528625488} +{"content": "Table of Contents\nAccording to the popular Mozilla company, Google Floc is a flop and unsecured premise privacy sandbox that does not protect the privacy and could lead to the serious risks.\nWhat is Floc Originally?\nFLoC is premised on a compelling idea: enable ad targeting without exposing users to risk, says Eric Rescorla, author of the TLS standard and the chief technology officer of Mozilla.\nSeveral privacy properties in the current design could result in significant risks if widely implemented in its current form.\nFLoC stands for Federated Learning of Cohorts, a initiative that seeks to develop alternative solutions to satisfy cross-site use cases without resorting to third-party cookies or opaque tracking mechanisms.\nIt enables marketers to guess users’ interests without requiring individual identification, eliminating the privacy implications of\ntargeted advertising. Currently, targeted advertising relies on techniques such as tracking cookies and device fingerprinting that reveal users’ browsing history across websites to advertisers and ad networks. What Else Does It Do?\nFLoC avoids the cookie by using a new “cohort” identifier that buckets users by their similar browsing behaviors.\nThis information can be\naggregated by advertisers to build a list of websites that users in a cohort visit, rather than using the visits made by the specific user, and then advertisers can target ads based on the cohorts’ interests. What Does Mozilla Have To Say about Floc?\nMozilla said that FLoC profiles can provide additional information about the FLoC as a whole. Taking into account the individual profiles, we can make generalizations about the FLoC cohort as a whole.”\nIn addition, the cohort IDs assigned to users are recalculated on the device weekly, which is intended to reflect their evolving interests over time and prevent them from being used as persistent identifiers to track users.\nAt some point next year,\nGoogle plans to replace third-party cookies with FLoC in its Chrome browser as an origin trial. Conclusion\nThis conclusion is supported by\nMozilla’s FLoC analysis. Even though a few thousand users share a cohort ID, it is possible to narrow down the list of users very quickly using fingerprinting data and the periodically recalculated cohort IDs as an easy way to differentiate users from one to the next.", "pred_label": "__label__POS", "pred_score_pos": 0.5200809240341187} +{"content": "Due to Denmark’s the low-lying characteristics, coastal areas are especially vulnerable to future effects of climate changes. The possible interaction between storm tides, storm water and rising groundwater increases the risk of flooding valuable regions. This requires a comprehensive approach to climate adaptation.\nThis webinar explorea our climate adaptation project to make the municipality of Dragør in the Øresund region climate resilient. A project that breaks down the barriers between coastal protection, nature conservation and the evolution of the changing cultural environment along the coast. Discover how, instead of fighting the forces of nature, seawater and storm water, we are reintroducing the natural forces of nature into a new, rich and changing mosaic landscape. By gradually retracting the dikes and by sustaining the natural wave-breaking effect of the foreland, we create a dynamic, resilient landscape. Presenters: Eva Sara Rasmusse - Commercial Manager and Landscape Architect, WSP in Denmark Jens Lauritz Hansen - Commercial Manager and Climate Adaptation Specialist, WSP in Denmark", "pred_label": "__label__POS", "pred_score_pos": 0.505486011505127} +{"content": "A blend of 9 probiotics that help brain function and may relieve nausea and gastrointestinal distress.\nKyo-Dophilus Multi 9 Probiotic combines nine different strains of beneficial Lactobacillus and Bifidus organisms to help maintain healthy intestinal function. This unique probiotic blend is carefully processed to retain viability at room temperature, ensuring an adequate number of living cells to colonize the intestine.\nThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\nSupplement Facts\nServing Size: 2 capsules\nServings Per Container: 45\nProprietary Probiotic Blend Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, Bifidobacterium longum MM-2, Bifidobacterium lactis, Bifidobacterium longum BB536, Bifidobacterium breve M-16V, Bifidobacterium infantis M-63, Lactobacillus gasseri LAC-343, Lactobacillus rhamnosus LCS-742\nOther ingredients: Starch (potato, tapioca and corn), gelatin, silicon dioxide, calcium phosphate.\nSuggested use: Adults take two capsules with a meal daily.\nConsult your healthcare professional before using this or any product if you are pregnant, nursing or under medical supervision.\nRefrigeration not required. Store in a cool, dry place with cap tight. Keep out of reach of children.", "pred_label": "__label__POS", "pred_score_pos": 0.6854197978973389} +{"content": "Uganda’s Coffee exports in August 2021 amounted to 700,990 60-kilo bags worth US$ 75.09 million (Shs264.7bn).\nThis comprised 636,458 bags of Robusta valued at US $65.24 million and 64.532 bags of Arabica valued at US$ 9.85 million.\nThis was an increase of 34.89% and 63.06 % in quantity and value respectively compared to the same month last year.\nBy comparing quantity of coffee exported by type in the same month of last Coffee Year (August 2020), Robusta increased by 39% and 70.98% in quantity and value respectively, while Arabica exports increased by 4.44% and 24.80% in quantity and value respectively, the report says.\nIncreasing Robusta exports during the month compared to the previous year were due to newly planted coffee which started yielding supported by favorable weather. This was also compounded by a positive trend in global coffee prices in the month of July and August as Brazil faced the threat of frost, which prompted exporters to release their stocks.\nThe modest increase in Arabica coffee exports with a correspondingly high increase in value compared to the same month last year was on account of higher global coffee prices as mentioned above.\nLower Arabica proportion in the export mix is a result of the off-year biennial cycle.”\nCoffee exports for the 12 months (September 2020-August 2021) amounted to 6,414,696 60-kilo bags worth US$ 607.81 million compared to 5,216,608-kilo bags valued at US$ 502.24 million the previous year (September 2019-August 2020). This represents 22.97% and 21.02% increase in both quantity and value respectively.\nThe quantity of coffee exported in August was the highest in a single month surpassing the previous month’s exports, while the total export quantity in 12 months was the highest in 30 years.\nDownload full report here: www.bit.ly/3lOfEyv", "pred_label": "__label__POS", "pred_score_pos": 0.9360249042510986} +{"content": "It's no secret that the power of leadership communication is its ability to drive results. In fact, strong leader communication is essential to the health of your organization because it stimulates employee engagement by:\nCreating focus about your organization's mission. Employees need to hear where the organization is heading and what it stands for, so it's best that these messages come straight from the leader. When leaders speak, employees listen. So, the more frequently leaders share messages about your organization's mission, the more likely employees will understand how to accomplish it.\nBuilding trust. You can't expect employees to freely grant trust in your leaders. Instead, leaders need to earn it. The more trust your employees place in leaders, the stronger employees' commitment and confidence in your organization will be.\nDispelling rumors. If you leave employees to draw their own conclusions about difficult topics like organizational change, they may automatically assume the worst. Why? Because in the absence of word from leaders, people create their own messages. However, leaders can get ahead of rumors, pave the way for transformational initiatives to run smoothly and help your organization be the best it can be.\nTo achieve employee engagement, leaders need to communicate often and well. But that's not easy. After all, if all your leaders do is recite dry facts, the only thing they'll accomplish is boring employees. So, what can you do to ensure your leaders communicate well? When helping them develop content, be sure these messages have the following characteristics.\nCompelling\nThe more emotionally connected employees feel to their leaders, the more trusting they'll be. Leaders can create this confidence in employees by sharing unique perspectives, speaking from the heart, going off script whenever they can and, most importantly, practicing what they preach. Instead of this: \"A few months ago, I traveled to various facilities on a listening tour to determine what team members thought about our values. The information we gathered indicated we needed a change.\" Try this: \"During my conversations with team members earlier this year, I heard several of you say that our values are too complicated, too difficult to understand and don't seem to align with the work that we do. So, I asked our HR team to use your input to simplify our values. I really appreciate all your great ideas. I believe that with them, we'll be able to develop values that better represent who we are as an organization.\"\nAuthentic\nWhen receiving updates about your organization, employees crave relatable, sincere conversation, not pre-scripted speeches filled with corporate jargon. To build rapport with employees, leaders should stay away from vague, packaged language. Instead, they should strive to be specific and conversational. You can help by writing talking points that meet these standards. Instead of this: \"Our revamped values are an exciting opportunity for employees. I'm confident that these values will achieve much more synergy within our organization, thereby optimizing how we work and allowing us to better achieve our strategic imperatives.\" Try this: \"I truly believe that our new values express who we are in a simple and compelling way while preserving our organization's character. They deeply touch me. For example, when I think about 'Passion,' one of our new values, I remember how so many of you consistently seek to exceed expectations. That's why I'm particularly excited about the addition of 'Passion' as one of our core values.\"\nEngaging\nDialogue is a key ingredient in effective leader communication. Employees don't want to feel like they're simply receiving orders, they want to feel like they're part of the process. That means leaders need to create an environment where employees have a chance to talk through topics. You can coach leaders on the importance of answering questions, listening to concerns and asking for ideas. Plus, you can give them a few prompts to help them start a conversation such as, \"What challenges do you think we'll face in achieving our objectives?\" or \"What questions do you have about this change?\" Instead of this: \"Our initiative to revamp our organizational values will affect various parts of the employee experience, including the performance management process and onboarding.\" Try this: \"We want our new values to be reflected in all parts of our organization, including the performance management process (PMP). We're currently working on integrating the values into the process and would love to hear your thoughts on how we can do this. What ideas do you have to add values to our PMP?\"\nConsistent\nLeaders need to develop a story and stick with it, as any deviation can cause confusion - or even distrust - among employees. Make sure your leader is armed with materials like a core deck, key messages and frequently asked questions (FAQs). These tools will help leaders stay on message and remember key takeaways. Instead of this: During the launch of the new values, your leader explains that the values were updated because they were outdated and no longer represent what the organization stands for. However, when asked how the PMP process is related to the new values during a town hall Q&A session, your leader mistakenly says, “We established new values to create a more effective PMP process.\" Now, employees are confused about why the values were updated: Was it because they no longer reflected the organization's culture, or because the PMP process wasn't effective? Try this: Provide your leader with a core deck, key messages and FAQs, so he or she knows how to talk about the updated values, as well as what questions to expect from employees. For instance, your FAQs can include a question regarding the PMP process: \"How is the PMP process related to the updated values?\" with a clear answer: \"We want our new values to be reflected in all parts of our organization, including the PMP. We're currently working on integrating the values into the process and will keep you updated.\" After reviewing the FAQs, your leader will be able to better remember key takeaways. For example: The values will be reflected in the PMP; however, the PMP is not the reason they were updated. Now, your leader will be equipped to deliver consistent messages to employees across the globe.\nAlison Davis\nAlison sets the strategic direction for Davis & Company and leads the development of new products and services. Since founding the company in 1984, she has provided senior counsel to clients such as American Water, BD and International Flavors & Fragrances. Alison has written or edited the books 49 Ways to Improve Employee Communications, The Definitive Guide to HR Communication, and Your Attention, Please. An online columnist for Inc.com, she frequently writes articles for leading business and trade publications.", "pred_label": "__label__POS", "pred_score_pos": 0.8204779028892517} +{"content": "To continue receiving Newsflash, please re-subscribe before March 1, 2017.\n*******************************************************************************************\nOn February 22, 2017 the World Trade Organization (WTO) announced the Trade Facilitation Agreement (TFA) had met its two-thirds WTO member ratification requirement as a result of Rwanda, Oman, Chad, and Jordan submitting their acceptance notices, allowing the agreement to enter into force.\nAccording to the announcement the TFA, “…seeks to expedite the movement, release and clearance of goods across borders, launches a new phase for trade facilitation reforms all over the world and creates a significant boost for commerce and the multilateral trading system as a whole.”\nIn 2015, WTO economists conducted a study on the effects of implementing the TFA and listed proposed benefits as follows:\nAverage trade cost reduction of 14.3% Approximately 1.5 days reduced on the importation of goods; a reduction of 47% Almost 2 days reduced on exports; a reduction of 91% Exports of global merchandise could benefit by an increase of approximately US$ 750 billion – US$ 1 trillion\nAdditionally, developing and least developed countries can predict to see a growth in the amount of exported products by as much as 20-35%.\nAdditional TFA information can be accessed at:", "pred_label": "__label__POS", "pred_score_pos": 0.7890264987945557} +{"content": "The assessment of relative model performance using information criteria like AIC and BIC has become routine among functional-response studies, reflecting trends in the broader ecological literature. Such information criteria allow comparison across diverse models because they penalize each model’s fit by its parametric complexity — in terms of their number of free parameters — which allows simpler models to outperform similarly fitting models of higher parametric complexity. However, criteria like AIC and BIC do not consider an additional form of model complexity, referred to as geometric complexity, which relates specifically to the mathematical form of the model. Models of equivalent parametric complexity can differ in their geometric complexity and thereby in their ability to flexibly fit data. Here we use the Fisher Information Approximation criterion to compare, explain, and contextualize how geometric complexity varies across a large compilation of single-prey functional-response models — including prey-, ratio-, and predator-dependent formulations — reflecting varying levels of phenomenological generality and varying apparent degrees and forms of non-linearity. Because a model’s geometric complexity varies with the data’s underlying experimental design, we also sought to determine which designs are best at leveling the playing field among functional-response models. Our analyses illustrate (1) the large differences in geometric complexity that exist among functional-response models, (2) there is no experimental design that can minimize these differences across all models, and (3) even the qualitative nature by which some models are more or less flexible than others is reversed by changes in experimental design. Failure to appreciate geometric complexity in the empirical evaluation of functional-response models may therefore lead to biased inferences for predator-prey ecology, particularly at low experimental sample sizes where the relative effects of geometric complexity are strongest. We conclude by discussing the statistical and epistemological challenges that geometric complexity poses for the study of functional responses as it relates to the attainment of biological truth and predictive ability.", "pred_label": "__label__POS", "pred_score_pos": 0.6930947303771973} +{"content": "UBC Theses and Dissertations LIN28B confers cancer stem-like phenotypes for neuroendocrine prostate cancer progression Lovnicki, Jessica Magdalena Abstract\nDue to the increased utilization of next generation anti-androgens to treat prostate adenocarcinoma (AdPC), therapy-induced neuroendocrine prostate cancer (t-NEPC) has become more prevalent. Although the mechanisms by which t-NEPC is established are not fully understood, emerging evidence suggests that AdPC cells can gain an intermediate pluripotent stem cell (SC)-like phenotype that can promote t-NEPC development. However, it remains unclear whether the core embryonic stem cell genes (ESCs) (LIN28, POU5F1, SOX2, and NANOG) regulate the stem-like state of prostate cancer cells and the switch from luminal epithelial to neuroendocrine lineage during the transition from AdPC to t-NEPC. We hypothesize that LIN28B plays a key role in the transition from AdPC to t-NEPC, and that the overexpression of LIN28B may promote proliferation and trans-differentiation, which may contribute to t-NEPC progression. By comparing the published RNA-seq data on AdPC and t-NEPC, we found that approximately 50% of t-NEPC patient tumors have gained LIN28B and SOX2 expression. Standard molecular and cellular biology techniques were applied to characterize the functions of LIN28B and its relationship with SOX2 using t-NEPC cell and xenograft models. We found that the mRNA levels of LIN28B and SOX2 are positively correlated in patient tumors, patient derived xenografts, transgenic mice, and multiple cell models. LIN28B and SOX2 expression was confirmed to be co-upregulated in a subset of t-NEPC patients by immunohistochemistry. Using our clinically relevant t-NEPC cell/xenograft model, DuNE, we demonstrated that LIN28B is essential for stem cell-like and neuroendocrine marker expression and cell morphology. LIN28B gene depletion by CRISPR inhibited DuNE xenograft initiation and tumor growth. These LIN28B functions are mainly mediated by its inhibitory effects on the microRNA let-7d, which resulted in the upregulation of HMGA2 and HGMA2 mediated SOX2 transcription. Overall, this thesis work adds to the understanding that the LIN28B/let-7/SOX2 axis is an important signaling pathway that regulates a cancer stem-like phenotype to promote t-NEPC development. Ultimately, this knowledge pertains to the clinical implications of LIN28B in informing future therapies that will be effective for managing t-NEPC.\nItem Media Item Citations and Data License\nAttribution-NonCommercial-NoDerivatives 4.0 International", "pred_label": "__label__POS", "pred_score_pos": 0.6542636156082153} +{"content": "Beschreibung\nThis book connects a buying psychology driven by American beliefs and values with a company's go-to market strategy, the goal being to sensitize readers to how the cultural values of a particular country or region can impact the business environment. The book also addresses the reasons behind these differences and therefore begins with a detailed cultural comparison of the United States and Europe, and assessments of how these characteristics impact their respective markets and customer behavior differently.Another aspect that sets this book apart is that it argues for sound decision-making processes as the first priority in any international business strategy. Readers are provided detailed insights into the variables a European company needs to understand before it makes its \"go/no-go\" decision, along with the tools needed to evaluate the probability of success and the risks of going to market. Once a company decides to enter the US market, the book then offers a highly customer-centric approach to developing and executing an effective market strategy. von Drews, Ralf und Lamson, Melissa", "pred_label": "__label__POS", "pred_score_pos": 0.8400611877441406} +{"content": "Friday, June 25, 2021 Turbulence Injuries\nOne of the most significant challenges experienced during the summer season is inclement weather, which often leads to turbulence.\nWhenever encountering turbulence,\nalways remain seated and secure yourself as quickly as possible. If you are in the aisle performing a service, brace the cart by wedging it between aisle seats, set the brakes, remove hot liquids from the top of the cart, and remain aware of the situation. Stay seated until the Captain tells you it is safe to get up. If an emergency should arise, use your best judgment, and communicate with the flight deck. The most important thing is always to keep yourself safe. : Important Reminders During the crew briefing, if you feel you have not received information concerning the possibility of turbulence during the flight, ask for additional information. If the flight deck crew advises you to take or remain in your jumpseat, do so – as quickly as possible, and remain seated until further advised. The flight deck crew will make an initial PA informing passengers of the turbulence—follow-up with subsequent announcements if necessary. If you experience moderate or severe turbulence, report via CERS within 24 hours of the event. If you are on an international sequence, report the incident within 24 hours of your return.\nInjured in Turbulence – What Next?\nIf you sustain an injury due to turbulence, notify the Captain immediately and request the turbulence and injury event be documented. If medical treatment is necessary, it is imperative to let the Captain know as soon as possible.\nAn Injury on Duty (IOD) may be filed 24/7 by calling: 844-777-8463\nA triage nurse from Sedgwick will answer your call. You are NOT required to follow the nurse’s recommendations and are free to seek immediate medical treatment. Advise the nurse if you intend to seek urgent medical care. Not all injuries require immediate medical attention. In the event of a medical emergency such as a head injury, do not wait to speak with a nurse- seek immediate medical attention, or go to the nearest hospital emergency room. If follow-up care is needed, be sure to talk with the registered nurse or your claims adjuster from Sedgwick.\nAll Flight Attendants should file a CERS Report.\nIt is always important to file a CERS report.\nThe CERS Report link can be found on your (EFB) tablet or the Flight Service website by clicking on Safety & Security, or you may connect from your mobile device. Additionally, consider submitting a Cabin ASAP report as it is an invaluable means of documenting specific safety concerns encountered onboard the aircraft.\nFor more information about turbulence safety, please refer to the Inflight Manual – Safety and Security – General Safety or contact the Safety Department at\nsafety@apfa.org\nThe Company and the APFA EAP recognize the\nCritical Incident Stress Management Program (CISM) as a collaborative policy that is jointly managed and monitored. CISD’s are scheduled for any aircraft accident or serious incident within 24-72 hours following an event and are designed to lessen or avoid the potentially negative impact of a traumatic event. JCBA Section 34.H.1. – The Company, upon notification of any aircraft accident, serious incident, or hijacking, or terrorist incident in which a Flight Attendant is involved, shall notify the APFA National President, APFA SSD Coordinator, and APFA EAP Representative. The Manager of Flight Service or her/his designee shall contact the APFA Base President when Flight Attendant(s) assigned to her/his respective base or involved in such incidents, emergency evacuation, or when a Flight Attendant is injured.\nc. Serious Incident: An incident with Flight Attendants onboard a Company aircraft\ninvolving any of the following:\nvi. Turbulence resulting in injuries to crew members or passengers\nIn Solidarity,\nBellia Peckson APFA National IOD Chair iod@apfa.org Vivian Stubblefield APFA Interim National Safety & Security Chair safety@apfa.org Abby Alconcher APFA National EAP Chair eap@apfa.org", "pred_label": "__label__POS", "pred_score_pos": 0.7268643379211426} +{"content": "Comprehensive Probiotic Blend for a Healthy Gut Microbiome\nResearch continues to demonstrate the emerging importance of probiotics and a healthy gut microbiome for protection against gastrointestinal issues such as inflammatory bowel syndrome and nutrient malabsorption.\nProbiotic Complete is a probiotic supplement made with a comprehensive seven-strain blend of gut-supporting microbial organisms (known as probiotics). Probiotic Complete contains some of the most embraced microbial strains for human wellness, with clinical evidence suggesting these beneficial probiotics may: Support a healthy gut microbiome Support a healthy inflammatory response Support immune function Support digestive function\nOther Ingredients: Microcrystalline cellulose, digestive resistant capsule (hypromellose, gellan gum), vegetable magnesium stearate. Recommendations: Take one capsule daily or as directed by your healthcare practitioner. Servings: 60. Cautions: If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use. Keep out of reach of children.\nThis product is shipped and fulfilled by NutriDyn", "pred_label": "__label__POS", "pred_score_pos": 0.8044134974479675} +{"content": "How do run-flat tires work?\nRun-flat inserts from Armormax\n® are not like conventional tires, which require air to stay hard. The run-flat tires have a reinforced sidewall that allows these tires to stay rigid without any air pressure.\nActually, they are designed to remain functional for a limited time without air pressure. On our heavy-duty inserts sometimes called an Armormax\n® donut can even be used without the existing tires on the vehicle.\nThe reinforced outer shell of run-flat tires keeps the rubber in place without air. It also supports the car to continue its journey. However, the sidewall of run-flat-tires is not designed to be permanent and is only recommended for around 50 miles of additional driving after the tire has deflated or shot out. To keep run-flat inserts and tires in good condition you have to check their depth, pressure, and condition often.\nFrequently Asked Questions Should I replace run-flat tires with regular tires?\nYou can replace run-flat tires with ordinary tires safely.\nHow many years do run-flat tires last?\nRun-flat tires are designed for short distances. They are zero pressure tires that can get you roughly 50 miles.", "pred_label": "__label__POS", "pred_score_pos": 0.960159182548523} +{"content": "Brookfield Property Partners (NASDAQ: BPY) and its affiliated real estate investment trust (REIT) Brookfield Property REIT (NASDAQ: BPYU) have a dilemma. They own some of the most iconic office buildings in the world and some of America's best shopping malls. While both real estate sectors are currently facing headwinds from the COVID-19 outbreak, Brookfield believes it has a bright future. Most private institutional investors tend to agree with Brookfield, which is why high-quality property values have held up reasonably well.\nUnfortunately, public market investors aren't on board with this thesis, which has weighed on the value of Brookfield's stock. That led its parent,\nBrookfield Asset Management (NYSE: BAM), to offer to acquire the rest of Brookfield Property that it doesn't already own. That proposal leaves investors wondering whether Brookfield Property is worth buying ahead of a potential deal. Here's the case for and against buying the global real estate giant these days. The case for buying Brookfield Property\nIn early January, Brookfield Asset Management offered to acquire all the shares of Brookfield Property that it didn't currently own for $16.50 a piece. The proposal would give existing investors a choice of accepting all-cash 0.40 shares of Brookfield Asset Management, or 0.66 Brookfield Property preferred shares for each share of Brookfield Property they currently own. Brookfield Asset Management structured that offer to appeal to all types of investors. Those who wanted to cash out could do so. Meanwhile, investors who desire further upside potential could accept Brookfield's shares. Finally, those seeking income could opt for the preferred equity.\nBrookfield Property is currently reviewing the proposal. It could accept the current deal structure, negotiate a better offer, or reject the bid and remain public. The most likely outcome is agreeing to slightly better terms with Brookfield Asset Management. Investors clearly want more, considering that Brookfield Property's stock currently trades at around $17.25 a share, implying they expect a higher offer. Further, management has repeatedly stated they believe the stock is significantly undervalued. On the other hand, it doesn't have much leverage considering that Brookfield Asset Management owns a majority stake. Thus, a deal seems likely at a slightly higher valuation.\nThat might not be a bad outcome for investors who buy ahead of a potential deal if they accept shares in Brookfield Asset Management. The company, which manages and invests in private equity funds and companies focused on real estate, renewable power, and infrastructure, has significant upside potential. The company ended the year with a business valued at $66 a share. Meanwhile, it believes it can grow its business's underlying value to $110 a share by 2025. With the stock currently trading at less than $42 apiece, it looks highly undervalued.\nThe case against buying Brookfield Property\nThere's a lot of uncertainty facing Brookfield Property these days. While it seems likely to reach a deal with Brookfield Asset Management at a higher value, they might not come to terms. If that happens, the stock will probably decline sharply, especially given the headwinds facing its office and real estate segments. The company might have to suspend or reduce its 7.7%-yielding dividend to conserve cash until market conditions improve. While a stand-alone Brookfield Property could create long-term shareholder value, it faces an uphill battle given the current market conditions and the likelihood that scuttling a potential deal would sour its relationship with its parent.\nMeanwhile, even if they agree to a deal, investors likely won't be able to convert all their shares into Brookfield Asset Management because of proration. Brookfield only wants to issue a maximum of 59.5 million of its shares, 42% of the total value offered. Because of that, investors will likely receive some cash and preferred stock in the deal, reducing their upside potential. However, they could sell the preferred stock and use the combined cash proceeds to buy more Brookfield shares to fully participate in its upside potential.\nBetter to buy the sure thing\nWhile Brookfield Property owns a valuable portfolio of commercial real estate, there's too much uncertainty about its future to buy it right now, given the possibility of a deal with Brookfield Asset Management. While that transaction offers upside potential in Brookfield Asset Management's stock, the merger could fall apart. Because of that, investors seem to be better off considering buying Brookfield Asset Management directly than buying its real estate affiliates right now.", "pred_label": "__label__POS", "pred_score_pos": 0.6573930978775024} +{"content": "CONTACT US:Contact info\nTackett JL, Daoud SL, De Bolle M, Burt SA. Aggressive Behav. 2013; 39(2): 149-159.\nDepartment of Psychology, University of Houston, Houston, Texas.\n(Copyright © 2013, International Society for Research on Aggression, Publisher John Wiley and Sons)\n23386551\nThe primary purpose of the present study was to examine support for the inclusion of relational aggression (RAgg) alongside physical aggression (Agg) and rule-breaking behaviors (RB) as a subfactor of antisocial behavior (ASB). Caregiver reports were collected for 1,087 youth (48.9% male) ages 6-18. Results indicated that all three subfactors of ASB demonstrated substantial loadings on a general ASB factor. Using a bifactor model approach, specific factors representing each ASB subfactor were simultaneously modeled, allowing for examination of common and specific correlates. At the scale level, results demonstrated consistently strong connections with high Neuroticism and low Agreeableness across all 3 ASB subfactors, a pattern which was replicated for the general ASB factor in the bifactor approach. Specific factors in the bifactor model demonstrated connections with personality and psychopathology correlates, primarily for Agg. These findings provide some support for an overall grouping of RAgg with other ASB subfactors in youth, and further distinguish Agg as potentially representing a more potent variant of youth ASB relative to both RB and RAgg. © 2013 Wiley Periodicals, Inc.\nLanguage: en", "pred_label": "__label__POS", "pred_score_pos": 0.6045435667037964} +{"content": "TAIPEI, 10 July 2018: The Taiwan government is committed to strengthening tourism through diversifying visitor source markets and upgrading facilities, according to Premier Lai Ching-te.\nThe government is committed to unlocking Taiwan’s rich tourism potential by diversifying visitor sources, upgrading facilities, and encouraging in-depth tours emphasising the local characteristics of each region, Premier Lai Ching-te noted last week.\nTo raise the country’s global tourism visibility, the government aims to create a national brand spotlighting Taiwan’s vibrant cultural attractions, food and natural environments, Lai said.\nAccording to the report in Taiwan Today, the premier claimed, arrivals are now topping 10 million annually.\n“Since diversification holds the key to sustainable tourism development, the government is working to entice more travellers from Europe, Northeast Asia and North and South America, and eyeing substantial future growth from emerging markets in Southeast Asia under the New Southbound Policy,” he said.\nA key plank in the government’s national development strategy, the policy seeks to enhance Taiwan’s agricultural, business, cultural, education, tourism and trade ties with the 10 Association of Southeast Asian Nations member states, six South Asian countries, Australia and New Zealand.\nThe Ministry of Transportation and Communications, which oversees the Tourism Bureau, said that the government has enacted measures to attract visitors such as easing visa regulations as well as fostering a Muslim-friendly travel environment through promoting halal certification and installing prayer rooms at major transportation hubs.\nVisitor numbers increased 17.32% year-on-year to 10.7 million in 2017. Arrivals also exceeded 10 million in 2015 and 2016. Tourists from New Southbound Policy targeted countries stayed for an average of 8.1 days and spent USD152.25 per day, the ministry said, adding that industry revenue from these markets totalled NTD2.8 billion (USD92.2 million) last year.", "pred_label": "__label__POS", "pred_score_pos": 0.6198567152023315} +{"content": "In March 2021, Raleigh Water will be sending a Reminder Letter to water customers whose backflow is due to be tested in April, May, and July (Irrigation Customers). To generate these Reminder Letters, our third-party contractor, BSI, had to complete an entire system restart. This restart currently portrays our online system as 100% compliant. If a containment backflow does not have a current backflow report on file, it is still considered a non-compliant assembly that requires a passing operational test report to be submitted online. A report is considered current if the operational test was completed less than one year prior to the test due date. To confirm your backflow test report(s) has been submitted, you may use the Customer Confirmation Number (CCN) located in the top right corner of your Reminder Letter to view your account online or contact BSI Online or by phone at 888-966-6050; or Raleigh Water and at 919-996-2747.\nThe Cross Connection Program is responsible for ensuring potable water provided by the City remains safe throughout the water distribution system and is protected from “backflow events.” (an undesirable reversal of potentially contaminated water\na customer from the City’s system.) to\nThis protection is achieved through the installation of backflow devices or assemblies after each metered service or the right-of-way for dedicated fire service lines. For most residential customers, backflow protection is provided by a dual check device in the meter box. For other services with higher risk, testable backflow assemblies are installed and required by Raleigh City Code to be tested by a Certified Tester. The results of the test are submitted to our web based system, BSI (Backflow Solutions Inc).\nFailing to adequately prevent or control backflow events could have significant negative health and economic impacts, as evidenced by the Corpus Christi, TX incident in December 2016.", "pred_label": "__label__POS", "pred_score_pos": 0.6326597929000854} +{"content": "The US Food and Drug Administration has issued another update to its ongoing evaluation of heater-cooler systems from different manufacturers, which are used to regulate the temperature of patients undergoing cardiothoracic surgery via sternotomy, and concerns over their associated risks of nontuberculous mycobacterial infections.\nTwo such companies, CardioQuip and Gentherm Medical LLC, have announced voluntary recalls for labeling updates that outline interim mitigation strategies for lowering the risk of such infections “while these manufacturers complete further testing for cleaning and disinfection validation, and aerosolization,” the agency said. CardioQuip initiated its recall of affected devices on July 30, Gentherm on June 7.\nTwo other companies, Maquet and Terumo, announced their recalls of affected devices on July 14 and April 30, respectively, and instructed centers “to discontinue use of their heater-cooler devices because these manufacturers will not be pursuing a cleaning and disinfection protocol that addresses the risks” of nontuberculous mycobacterial infections.\nThe FDA statement follows its February announcement that it had approved similar labeling changes for the LivaNova Heater-Cooler System 3T, which featured “validated cleaning and disinfection instructions” and an aerosol collection system “to reduce (but not eliminate) the risk of potential emission of aerosols.”\nThe FDA reassures that “in appropriately selected patients, the benefits of temperature control during open chest cardiothoracic procedures generally outweigh the risk of infection transmission.”\nContent Source: https://www.medscape.com/viewarticle/960864?src=rss", "pred_label": "__label__POS", "pred_score_pos": 0.6013624668121338} +{"content": "Personalized Energy Plans (PEP talks) Contact us:\nInteractive energy audits are transforming the relationships between customers and their utilities.\nDNV’s PEP Talks provides utilities with a simple way to engage with customers, integrate them into the energy savings process, and develop one-on-one relationships in ways that were never before possible. Utility customers are eager for ways to save money and conserve energy at their properties. Our modernized approach to the in-person energy audit gives utilities the capability to do both of these, while also reducing risk and operational cost for themselves.\nHow it works Once paired with a utility energy advisor, customers are given expert insights into their building’s energy performance. This is done via smartphone or tablet in our interactive platform which is driven by a video-based customer experience. The property owner simply clicks on a link sent to their mobile device without the need to even download an app onto their device.\nDuring the visit the energy advisor gets a live view from the customer perspective itself. In addition to standard functionality, our platform also has advanced capabilities including Optical Character Recognition (OCR), a technology which enables the energy advisor to capture barcodes on specific equipment to identify whether a device qualifies for an instant incentive. Features like this allow the utility to offer an individualized approach for each customer and ultimately grow the long-term relationship.\nThe power of the remote energy audit This past year has proven the performance of DNV’s remote solutions like PEP Talks. Even before our global health challenge, utility visits to properties could be a headache as they present challenges like adverse driving conditions, allergens, unpredictable pets, and on-site hazards. Those challenges are compounded for those utilities servicing remote areas. DNV PEP Talks solves those issues while driving modernization of the home energy audit. Now a utility not only eliminates time to reach a property, but can also complete the experience inside one hour, opening the potential for a higher volume of consultations. This means ease of scheduling, saving more energy and offering your customer a far more engaging process for enhanced trust.\nEVOLVE\nIts easy to take insights from DNV’s PEP Talks to the next level. Our EVOLVE Digital Suite seamlessly integrates insights from virtual audits into existing systems, helping utilities accelerate energy program success. EVOLVE 360 streamlines program management and connects utilities, customers, trade allies, and distributors to valuable insights, resources, and incentives to improve energy performance. Screen captures, nameplate optical character recognition (OCR) scans, notes, and additional data get uploaded to EVOLVE 360 and log energy performance opportunities. This allows Energy Advisors to remain fully focused on customers, knowing that data is being transferred safely for further analysis.", "pred_label": "__label__POS", "pred_score_pos": 0.643279492855072} +{"content": "About 30% of melanoma cases arise from an existing nevus. More commonly known as moles, Nevi are skin growths that develop when pigmented cells accumulate in a cluster. While melanoma is characterized by highly mutated, malignant cells, moles are benign. However, because moles can develop into skin cancer, dermatologists recommend regular monitoring for changes or irregularities.\nA recent study published in\nScience Advances uncovered a powerful subset of white blood cells with potent cancer-fighting potential. Notably, common moles naturally contain these critical immune cells. This research identified a novel strategy that activates these cells resulting in a robust anti-tumor immune reaction.\nThe researchers used a specialized mouse model system to test the immune mediators naturally residing inside a mole. Moles removed from patients were transplanted onto immunodeficient mice. These mice possess immune cells which lack the functionality required for an immune response. Therefore, immune mediators transferred within the mole are likely responsible for any immune reactions detected in this system.\nOver 80% of the moles experienced spontaneous regressions while the remaining moles remained stable, exhibiting no change in size or shape. When compared to stable moles, the regressed moles contained significantly higher numbers of CD4+ T cells. The expansion of these cells coincided with mole regression, indicating that activation of this subset of immune cells is driving the immune response against the pigmented cells in the mole.\nThe study also investigated the role of regulatory T cells (Tregs) in the spontaneous regression of the transferred moles. Tregs are immune cells that regulate the immune response by suppressing immune mechanisms to prevent autoimmune diseases and chronic inflammation. However, in the context of cancer, Tregs can also limit anti-tumor immune responses.\nTregs are dependent on a cytokine called IL-2 which is not present in the murine system used in this study. When mice were administered IL-2 following transplantation of a patient mole, most moles remained stable. However, as soon as IL-2 treatment ceased, most of the moles began to regress. These findings suggest that Tregs located within the mole may be to blame for the stability of benign moles present in many adults.\nImportantly, this study also demonstrated that mice who reject the transplantation of a mole receive protection from future melanoma growth. This finding suggests that the immune response mounted against a mole could also provide anti-tumor immunity towards melanoma.\nThe authors advocate that activating CD4+ T cells, which are already present in moles, may present a novel therapeutic strategy for melanoma treatment or prevention.", "pred_label": "__label__POS", "pred_score_pos": 0.9970102310180664} +{"content": "While many birds are leaving Michigan in the fall to head for warmer wintering grounds down south, two of our most handsomely marked sparrows are moving in from even farther north. White-crowned and White-throated Sparrows are both relatively large songbirds with boldly black-and-white patterned heads that are common across backyards and parks during the spring and autumn months in southeast Michigan. The White-crowned can be distinguished from its close relative by its more grayish overall appearance, its pale orange bill, and its lack of two features found on the White-throated Sparrow. The White-throated is easily identified by the namesake white throat patch and yellow marks above the eyes. The White-crowned comes from further north, nesting in Alaska and northern Canada, and is often only around for a brief stopover during migration with peak numbers in April and October. Both sparrows feed in groups on seeds and berries on or near the ground and will readily come to feed on spilled seeds beneath a backyard birdfeeder. You can increase your likelihood of seeing these birds in your own yard by placing feeders within a short flight from bushes or brush piles for cover. When foraging, they use a characteristic “double-scratching” method which involves a sliding hop backwards to remove leaf litter or dirt followed by a quick forward hop within the same motion to land back where they started. White-crowned Sparrows aren’t born knowing their song, they learn it within the first few months of their life by listening to adults. As a result of this, they have regional dialects across the country and have been the subject of many research studies on bird songs.", "pred_label": "__label__POS", "pred_score_pos": 0.875230073928833} +{"content": "Originally Aired: October 5, 2021 Time: 8:00 am PT, 11:00 am ET, 17:00 CET\nWe are all keenly aware that viruses can negatively impact our lives, but what about viruses that shape our existence and even improve some of its outcomes? In the past several decades, advances in cell and gene therapies have exploded due to innovations with adeno-associated virus (AAV). Yet, given its small genomic size, the life cycle of AAV is surprisingly complex. Understanding this life cycle will be pivotal to developing new and improved methods of AAV vector manufacture that can meet the industry’s increasing needs. Interestingly, in nature, AAV co-exists with adenovirus, with the latter providing help during the AAV life cycle. Thus, taking cues from nature, investigators have developed a novel tetracycline enhanced self-silencing adenoviral (TESSA) helper system that allows for contaminant-free AAV manufacture.\nIn this\nGEN webinar, our notable presenter Dr. Ryan Cawood will discuss how TESSA technology enhances both AAV production yields and particle quality by suppressing adenoviral late gene expression. Moreover, he will explain how using this technology in other systems such as the HeLa-RC32 cell line, which encodes the AAV Rep and Cap genes, has led to several important discoveries regarding AAV biology, including the identification of a previously unknown interaction between adenoviral late proteins and specific AAV sequences, and a more thorough understanding of the previously reported AAV cis-acting replication enhancer (CARE; a region of DNA surrounding the AAV p5 promoter). Dr. Cawood will discuss these findings and their implications for scalable AAV manufacturing strategies. A live Q&A session followed the presentations, offering a chance to pose questions to our expert panelists.\nWebinar produced with support from:", "pred_label": "__label__POS", "pred_score_pos": 0.8857787847518921} +{"content": "Evaluation of a fentanyl drug checking service for clients of a supervised injection facility, Vancouver, Canada.Harm Reduct J. 2018 09 10; 15(1):46.HR BACKGROUND\nBritish Columbia, Canada, is experiencing a public health emergency related to opioid overdoses driven by consumption of street drugs contaminated with illicitly manufactured fentanyl. This cross-sectional study evaluates a drug checking intervention for the clients of a supervised injection facility (SIF) in Vancouver.\nMETHODS\nInsite is a facility offering supervised injection services in Vancouver's Downtown East Side, a community with high levels of injection drug use and associated harms, including overdose deaths. During July 7, 2016, to June 21, 2017, Insite clients were offered an opportunity to check their drugs for fentanyl using a test strip designed to test urine for fentanyl. Results of the drug check were recorded along with information including the substance checked, whether the client intended to dispose of the drug or reduce the dose and whether they experienced an overdose. Logistic regression models were constructed to assess the associations between drug checking results and dose reduction or drug disposal. Crude odds ratios (OR) and 95% confidence intervals (CI) were reported.\nRESULTS\nAbout 1% of the visits to Insite during the study resulted in a drug check. Out of 1411 drug checks conducted by clients, 1121 (79.8%) were positive for fentanyl. Although most tests were conducted post-consumption, following a positive pre-consumption drug check, 36.3% (n = 142) of participants reported planning to reduce their drug dose while only 11.4% (n = 50) planned to dispose of their drug. While the odds of intended dose reduction among those with a positive drug check was significantly higher than those with a negative result (OR = 9.36; 95% CI 4.25-20.65), no association was observed between drug check results and intended drug disposal (OR = 1.60; 95% CI 0.79-3.26). Among all participants, intended dose reduction was associated with significantly lower odds of overdose (OR = 0.41; 95% CI 0.18-0.89).\nCONCLUSIONS\nAlthough only a small proportion of visits resulted in a drug check, a high proportion (~ 80%) of the drugs checked were contaminated with fentanyl. Drug checking at harm reduction facilities such as SIFs might be a feasible intervention that could contribute to preventing overdoses in the context of the current overdose emergency.\nMeSH Pub Type(s) Language PubMed ID Citation Harm Reduction Journal,vol. 15, no. 1, 2018, p. 46. Harm Reduct J. 2018;15(1):46. Harm Reduction Journal, 15(1), 46. https://doi.org/10.1186/s12954-018-0252-8 Harm Reduct J.2018 09 10;15(1):46. PubMed PMID: 30200991.", "pred_label": "__label__POS", "pred_score_pos": 0.5475256443023682} +{"content": "Sounding Board “I now see how owning our story and loving ourselves through that process is the bravest thing that we will ever do.” – Brené Brown\nA sounding board is a session with someone you can share your thoughts, concerns, and ideas rather than thinking and contemplating alone.\nSounding Board encourages objective self-evaluation by providing a confidential environment for you to “hear” and “see” your own thoughts being spoken out loud without being judged. This concept has been widely used across industries and professions including medical, insurance, education, corporate, and performing arts.\nWhen faced with on-going personal or professional issues, having someone to talk to can make us feel less alone with our problems.\nA sounding board offers a private moment with a listening ear for you to speak your thoughts, contemplate, and reflect.", "pred_label": "__label__POS", "pred_score_pos": 0.9249544143676758} +{"content": "The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has approved two new and rare possible side effects associated with the use of vaccines by Janssen and AstraZeneca, a subsidiary of Johnson & Johnson (J&J), LETA informed the State. Medicines Agency.).\nThe rare side effects of J&J are venous thromboembolism and immune thrombocytopenia, while AstraZeneca has been shown to have one of these, immune thrombocytopenia. However, the EZA decided that the benefits of Covid-19 outweigh its risks.\nThe MAH stressed the need for healthcare professionals to evaluate the suitability of these vaccines for people at risk of these potential side effects. If a person has a history of immune thrombocytopenia, the doctor should assess the risk of low platelet counts before vaccination, and monitoring of platelet counts after vaccination is recommended.\nRead more:\nInformation on these two side effects has been sent to healthcare professionals and vaccinators in Latvia.\nThe MAH also urges residents who have received the J&J and AstraZeneca vaccines in the last month to pay attention and seek immediate medical attention if they experience shortness of breath, chest pain, leg pain, leg swelling, pain persistent abdominal, spontaneous bleeding or hemorrhage. minor subcutaneous hemorrhages. When diagnosed early, both diseases respond effectively to treatment, ZVA emphasized.\nAccording to LETA estimates, according to the National Health Service (NSS), 25,387 people have received the J&J vaccine in the last month, and 12,685 people have been vaccinated with the AstraZeneca vaccine.\nThese vaccines are not given to adolescents.\nThe Pfizer / BioNTech vaccine, which has been received by 125,040 people in the last month, is many times more popular in Latvia.\nThe MAH indicates that the most common side effects of Covid-19 vaccines are usually mild to moderate and resolve within a few days of vaccination. These include flu-like symptoms such as fever, fever, headache, dizziness, tiredness, drowsiness, muscle and joint pain, and nausea, diarrhea, and vomiting.\nIntrovert. Beer guru. Communicator. Travel fanatic. Web advocate. Certified alcohol geek. Tv buff. Subtly charming internet aficionado.", "pred_label": "__label__POS", "pred_score_pos": 0.5288234353065491} +{"content": "Abstract\nThis paper aims to find the impact of COVID-19 on Manipal Academy of Higher Education (MAHE) libraries and the measures taken to overcome the challenges in accessing the information during the COVID-19 situation and render services to the users. A structured questionnaire was prepared and distributed to ten libraries of MAHE at Manipal, India campus. The study revealed that the COVID-19 pandemic has a significant impact on the usage of resources and services provided by MAHE libraries. The libraries were kept open, but the working hours of the libraries have been reduced during the COVID-19 pandemic. The study found that the majority of the libraries have seen a significant decrease in the use of physical resources and an increase in the usage of digital resources. The majority of the respondents agreed that online assistance to projects and research had been provided. The analysis reveals that limiting the number of users into the physical library, mandatory face mask, provision of sanitizers at the library entrances and maintenance of social distancing were some of the measures taken by the libraries of MAHE during the COVID-19 pandemic. The study revealed that MAHE libraries have a rich collection of e-books, online journals, online databases, e-learning platforms and research support tools. Remote access facility was extensively used by the users of MAHE libraries to access the relevant literature for teaching, learning, patient care and research activities and thus to meet their information needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9633499383926392} +{"content": "Study: Inefficiencies, lack of transparency sinking competition, delaying Puerto Rico’s recovery\nDespite the allocation of federal funds that exceed $62 billion, Puerto Rico’s recovery has faced multiple delays, and because a large portion of reconstruction projects are delegated to contractors, nonprofit Sembrando Sentido carried out a study on public contracting processes with Community Development Block Grant (CDBG-DR) funds, to identify the causes of the delays, their impact, and potential solutions.\nThe study identified that while the Puerto Rico Department of Housing discloses information on procurement and contracts in their CDBG-DR website, the agency does not publish key information on needs assessments, contract progress, and/or payments.\nAdditionally, municipalities, agencies, and non-governmental organizations (NGOs) implementing reconstruction projects with CDBG-DR funds, with allocations of over USD 838 million are not required to disclose information regarding their procurement processes on the CDBG-DR page.\n“If information is published in dozens of different media channels and formats, local companies will struggle to learn about contracting opportunities, and citizens won’t be able to know how CDBG-DR funding is used, its progress and results,” said Issel Masses, executive director of Sembrando Sentido.\nIn terms of efficiency, the evaluation revealed that competition (with an average of ~3.4 eligible bidders per tender) is limited, and the period of evaluation and award of contracts (~147 days or ~4.8 months on average), points to significant delays in contracting.\nThe study also includes an equity analysis that shows how the disparity between funds awarded to Puerto Rican (~ 36%) versus the United States contractors (~ 63%) persists.\n“Even when accounting for subcontracts, local vs. foreign contractor distribution does not improve,” said Masses, stressing the need to explore strategies that promote and increase the participation of local companies in public procurement to promote local economic development and facilitate the transfer of skills.\nSembrando Sentido also presented recommendations for each of the identified weaknesses. Among these, the organization calls for the centralization of all contracting data with CDBG-DR funds under a single website.\n“We also urge greater accountability and continuity in participation efforts, so that anyone can become an active part of the reconstruction projects that affect them,” said Masses.\nThe study is part of ContratosEnLey.org, an initiative by Sembrando Sentido, a nonprofit organization that “aims to advocate, develop, and maintain robust, transparent, responsive, and inclusive public contracting processes in Puerto Rico.”\nMasses founded the organization after more than a decade of professional experience in international public policy, working from Washington with the World Bank and other institutions, and collaborating with organizations such as the Organization of American States and the United Nations.\nAfter Hurricane Maria, Masses decided to return to Puerto Rico to contribute to efforts that promote a more inclusive, open, and robust governance, at a time when billions of dollars are to be invested in the reconstruction and recovery of the island.", "pred_label": "__label__POS", "pred_score_pos": 0.5114431977272034} +{"content": "How Local Government Can Support Playgroup\nLocal Governments have been supporting community playgroups since they started in the 1960’s. Community playgroups are by their nature place-based and community driven by local families. Often a key factor in their ongoing existence are the partnerships they enter into with their local governments.\nThe following resource was designed to be used by local government professionals in their planning and community development. It outlines the steps local governments can take to support and encourage a vibrant community playgroup sector.\nTo read more, click here:", "pred_label": "__label__POS", "pred_score_pos": 0.9969872236251831} +{"content": "Stop the Spread Campaign\nTo end this public health crisis, we must do all we can to stop the spread of COVID-19\nUpdated September 2021\nCOVID-19 is deeply impacting our members, patients, and communities. During the pandemic, we are working to address our members’ needs and the needs of their patients. It is imperative that we do all we can to stop the spread of disease and end this public health crisis.\nVaccination is Key\nVaccination is key to protecting against severe disease and saving lives. COVID-19 vaccines are effective at helping protect against severe disease and death from variants of the virus that causes COVID-19 currently circulating, including the Delta variant.\nACOG recommends that all pregnant individuals be vaccinated against COVID-19. This recommendation reflects evidence demonstrating the known safety of the vaccines and the increased risk of severe complications associated with COVID-19 infection.\nMitigation Guidance\nACOG also continues to support the CDC’s COVID-19 mitigation guidance: Mask-wearing requirements are part of a comprehensive public health strategy to help reduce the spread of COVID-19 including in schools and on public transit.\nHelp Spread the Word\nDon’t forget to sign the open letter from obstetrician–gynecologists to the public encouraging that every eligible person be vaccinated against COVID-19. This letter will be a powerful tool for advocacy and education. Sign your name today!\nAdditional Resources Statements Recommending Vaccination of Pregnant Individuals Statement in Support of COVID-19 Vaccine Mandates External Resources and Guidance AAP Guidance: COVID-19 Guidance for Safe Schools (aap.org) ACP Statement: ACP Says Masks Should be Required in Schools CDC Guidance: How to Protect Yourself and Others Additional Resources for Patients Resources for Patients in Support of COVID-19 Vaccines Frequently Asked Questions: Coronavirus (COVID-19), Pregnancy, and Breastfeeding Frequently Asked Questions: Coronavirus (COVID-19) and Women's Health Care Infographic: Why Should I Get the COVID-19 Vaccine While I'm Pregnant?", "pred_label": "__label__POS", "pred_score_pos": 0.8110672235488892} +{"content": "The presence and distribution of apoptotic cell death in multiple system atrophy (MSA) and morphologically related diseases were investigated by means of a modified terminal deoxynucleotidyl transferase-mediated nick end labeling method, comparing their distribution with that of glial cytoplasmic inclusions, immunohistochemically demonstrated bcl-2 protein, bax protein, CD95, TNFalpha, and p53-protein expression, as well as activated microglia. Apoptosis occurred almost exclusively in oligodendrocytes in multiple system atrophy and its general distribution was comparable to the already known oligodendroglial pathology in this disorder. Additionally, in about a quarter of glial cytoplasmic inclusions, there was upregulation of bcl-2-protein and coexpression with ubiquitin, suggesting a final attempt of involved cells to counteract apoptotic cell death. Bax protein was also demonstrated in oligodendroglial cells. A significant neuronal apoptosis was not observed in MSA; these cells might be destroyed secondarily to oligodendroglial apoptosis by necrosis or other forms of programmed cell death. These results emphasize the central role of oligodendroglial pathology in multiple system atrophy, making this disease unique among neurodegenerative diseases.", "pred_label": "__label__POS", "pred_score_pos": 0.9881046414375305} +{"content": "Abstract\nOwing to its vast natural resources and the influence of the Congo River and associated submarine canyon, the Angolan continental margin is of both socioeconomic and ecological interest. The deep-sea ecosystems of the region are nevertheless understudied, and much of the deep-sea fauna remains undescribed. Here, we document the scavenging amphipods of the Angolan deep-sea habitat, which provides valuable new insights into the ecology of Angolan deep-sea scavengers. This can be used as an ecological baseline, against which resource-extraction impacts can be measured. A total of 7996 scavenging amphipods, representing 10 species, were identified. At least four species were new to science. The relatively low scavenger diversity of the region, combined with the large sample sizes, may be indicative of abundant food falls in the region due to the presence of the submarine canyon system. The dominant species across all samples,\nAbyssorchomene distinctus (Birstein and Vinogradov, 1960), was the focus of a population-level study, which was used to describe the population structure of this species and identify species traits. Of the 826 individuals of A. distinctus dissected and measured, 533 were unsexed juveniles, 149 were male, and 144 were female. Females were significantly larger than males, which is indicative of non-mate-guarding pre-copulatory behaviour, but had significantly shorter antennae, which may indicate that males use chemical cues during mate searching. Two, three, and five discrete size-based cohorts were identified for juveniles, males, and females respectively. No ovigerous females were caught but brood size of A. distinctus was estimated to be 10-38 offspring based on ovary contents. Keywords Angola Congo Submarine Canyon continental margin population ecology", "pred_label": "__label__POS", "pred_score_pos": 0.7530608773231506} +{"content": "Flashcards in 23 - Urologic Diseases I Deck (38)\nLoading flashcards...\n1\nWhat should you focus on for these lectures? - Diagnosis and treatment - Don't worry about pathology as much\n2\nWhat is hematuria? - Gross hematuria: visible blood in urine - Microscopic hematuria: > 3 red blood cells per high powered field (RBCs/HPF) on two of three urine specimens - May originate from anywhere along the urinary tract\n3\nWhat is nephrologic/glomerular hematuria? - Significant proteinuria is also present with hematuria (>1 gm/24 hours) - Dysmorphic red blood cells - Red cell casts (means nephrologic origin) - Warrants nephrology evaluation\n4\nWhat are common causes of non-glomerular hematuria when it is from the UPPER urinary tract? - Urolithiasis - Pyelonephritis - Renal cell cancer - Urothelial/Transitional cell carcinoma - Urinary obstruction\n5\nWhat are common causes of non-glomerular hematuria when it is from the LOWER urinary tract? - Bacterial cystitis (UTI) - BPH - Prostatitis - Urothelial/Transitional cell carcinoma - Spurious (false) hematuria (e.g. menses, vaginal atrophy) - Instrumentation\n6\nWhat will you do in a hematuria evaluation? - UA with microscopic analysis - Urine culture (if indicated) - Urine cytology/tumor markers - Upper urinary tract imaging (renal US, intravenous urogram, or CT urogram) - Cystoscopy - 10-20% of patients evaluated will be diagnosed with a urologic malignancy\n7\nWhat is a urinary calculi A stone Stones are formed because solutes in urine precipitate and aggregate.\n8\nWhat can stones be composed of? - calcium oxalate (monohydrate or dihydrate) - uric acid - struvite (magnesium ammonium phosphate) - calcium phosphate - cystine (uncommon)\n9\nDescribe the clinical presentation of a patient with a urinary calculi (stone) Very common - Acute onset, colicky flank pain radiating to the groin or scrotum due to ureteral obstruction causing renal capsular and ureteral distention - Renal and ureteral colic are often considered among the most severe pain experienced by patients - Lower quadrant pain, urinary urgency, frequency, and dysuria as the stone approaches the ureterovesical junction, - Distressed patient, often writhing, while trying to find a comfortable position - Costovertebral angle or lower quadrant tenderness may be present - Nausea and vomiting\n10\nHow do you diagnose a urinary calculi (stone)? ******* THIS IS IMPORTANT ******* - Gross or microscopic hematuria is present in approximately 90% *** Gold standard: Computed tomography (CT) scan of the abdomen and pelvis WITHOUT oral or intravenous contrast *** KNOW CT, do NOT use contrast *** Others - KUB Xray - IVP\n11\nWhat are the four indications for urgent intervention with urinary stones? ******* THIS IS IMPORTANT ******* - Obstructed upper tract with infection - Impending renal deterioration - Pain refractory to analgesics - Intractable nausea/vomiting **** KNOW THESE ****\n12\nWhat are three management options for urinary stones? - Strain urine for stone passage - Medical expulsion therapy - Oral stone dissolution\n13\nDescribe medical expulsion therapy Alpha blockers Calcium channel blockers NSAIDS\n14\nDescribe oral stone dissolution therapy Uric acid stones only Urinary alkalinization Potassium citrate, sodium bicarbonate\n15\nWhat is the chance of passing a ureteral stone? *****KNOW THIS ****** KNOW THIS - 2/3 of ureteral stones will pass within 4 weeks of the onset of symptoms - Complete obstruction is rare so risk of renal deterioration from observation is presumed low - If stone has not passed within 4 weeks, intervention is usually needed KNOW 4 WEEKS ***\n16\nHow can you use the size of the stone in order to determine the likelihood you will need intervention? *******KNOW THIS ******* - Stone 6 mm (80% will need intervention) KNOW THIS\n17\nWhat are the three surgical stone intervention options? - Extracorporeal Shock Wave Lithotripsy (ESWL) - Ureteroscopy +/- laser lithotripsy - Percutaneous nephrolithotomy (PCNL)\n18\nDescribe Extracorporeal Shock Wave Lithotripsy (ESWL) Extracorporeal Shock Wave Lithotripsy (ESWL) - 4-15 mm stones in kidney or proximal ureter - Stone must be radio-opaque\n19\nDescribe ureteroscopy +/- laser lithotripsy All stones amendable but large renal stone treatment is tedious\n20\nDescribe percutaneous nephrolithotomy (PCNL) - Renal calculi >15-20 mm - Most invasive treatment\n21\nHow can you prevent stones? DRINK WATER ***** - 2.5-3 L/day) Dietary modifications - Low animal protein, low sodium, low oxalate diets - NORMAL dietary calcium intake - Citrate therapy If this doesn't help patient... - Full metabolic evaluation\n22\nWhat are the two type of renal cysts we have? - Benign - Malignant\n23\nDescribe a benign renal cyst Benign - Present in 50% of people age > 50 - Fluid filled epithelial lined cavity in renal parenchyma - Typically asymptomatic - No treatment required unless very large and causing pain\n24\nWhat is an angiomyolipoma? Benign solid renal tumor Contains three components: - Proliferation of blood vessels - Smooth muscle - Adipose tissue Frequently associated with Tuberous sclerosis\n25\nWhat is the presentation of a patient with angiomyolipoma? - Typically an incidental finding on imaging study - Spontaneous bleed occurs in 10%\n26\nWhat property of the angiomyolipoma determines your treatment method? Larger than 4 cm *** - Treatment needed Smaller than 4 cm *** - Don't treat unless patient has symptoms that interfere with their life - If there is an atypical appearance, consider treating KNOW 4 cm ****\n27\nWhat are the treatment options? Selective embolization Partial nephrectomy Radical nephrectomy\n28\nWhat do you NEED to know about diagnosing angiomyolipomas? ****** KNOW THIS ***** The presence of even a small amount of fat within a renal lesion on CT scan virtually excludes the diagnosis of renal cell carcinoma and is considered diagnostic of AML If there is ANY fat, it is BENIGN (angiomyolipomas)**** Not 100% positive, so still observe the angiomyolipomas, but don't do a biopsy\n29\nWhat is an oncocytoma? - Benign tumor derived from distal tubules - Most renal oncocytomas cannot be differentiated from malignant renal cell carcinoma by clinical or radiographic measures - Biopsy also is often indeterminate - Need to treat aggressively as if malignant **** This is one that you DO TREAT because you cannot tell if it is malignant or not *****\n30", "pred_label": "__label__POS", "pred_score_pos": 0.9186970591545105} +{"content": "Transport for London are consulting on an expansion of the cycle superhighways network, which business leaders warn could have a significant economic cost.\nUnder the Mayor of London’s plans, Europe’s longest substantially-segregated urban cycleways would be created. Two continuous cycle routes almost completely separated from traffic would cross central London from east to west and north to south.\nThe north-south route would run for just 3 miles from Elephant & Castle to King’s Cross. However, the east-west route will run from Barking to Acton, a distance of over 18 miles, including a section on the Westway flyover, where one lane will be removed to create a segregated cycle track.\nRegular users of the Westway will know it is not the most free flowing of roads already, so this could lead to significant extra traffic congestion, not just on the elevated section, but on surrounding roads as drivers avoid it.\nResponding to TfL’s consultation on new cycling superhighways, London First Infrastructure Director David Leam said: “We welcome the Mayor’s ambition to improve London’s cycling infrastructure and get more Londoners on their bikes in a safer environment.\n“However, this must not make life worse for those on London’s buses, cars, taxis, coaches and vans. As well as moving commuters, London’s roads ensure we get the goods and services we need where and when we need them.\n“TfL’s own consultation acknowledges that these proposals would mean longer journey times on key cross-London routes and on the roads approaching them. This could have a significant economic cost. In the absence of complementary proposals from TfL, these plans offer the dispiriting prospect of jams today and jams tomorrow for many Londoners”.", "pred_label": "__label__POS", "pred_score_pos": 0.969340443611145} +{"content": "Dietary fiber is essential for a daily mealIncrease your fiber intake. It's a phrase you've probably heard before. But do you realize why fiber is so beneficial to your health?\nDietary fiber, which is mostly found in fruits, vegetables, whole grains, and legumes, is well recognized for its ability to prevent and treat constipation. Fiber-rich meals, on the other hand, can help you maintain a healthy weight while also lowering your risk of diabetes, heart disease, and certain types of cancer.\nIt's not difficult to find pleasant fiber-rich foods. Learn how much dietary fiber you need, what foods contain it, and how to incorporate it into your meals and snacks.\nWhat is the significance of dietary fiber?\nDietary fiber, commonly referred to as roughage or bulk, refers to the components of plants that your body cannot digest or absorb. Fiber is not digested by your body, unlike other meal components such as lipids, proteins, or carbohydrates, which your body breaks down and absorbs. Instead, it passes through your stomach, small intestine, and colon relatively undamaged before exiting your body.\nFiber is typically divided into two types: soluble fiber that dissolves in water and insoluble fiber that does not dissolve in water.", "pred_label": "__label__POS", "pred_score_pos": 0.9941924214363098} +{"content": "The uncovering of the molecular acrobatics of a key cell enzyme could lead to new treatments for cancer and metabolic diseases such as obesity and diabetes. A recent molecular discovery has plenty of treatment implications. The cell enzyme is called PI3KC2A, and though scientists knew that it controlled many crucial cell functions, they remained unsure\nArsenic is infamous for its harmful properties. However, some arsenic compounds— in carefully measured doses — can be used in medical treatments. One such compound might even help treat cancer, researchers say. How can an arsenic oxide help treat cancer? A new study investigates. Arsenic is often listed as a carcinogen, which is a substance", "pred_label": "__label__POS", "pred_score_pos": 0.9969928860664368} +{"content": "Panic Disorder\nAlternate Names : Panic Attacks, Acute Panic Attacks\nA panic disorder is characterized by repeated panic attacks, or episodes of intense fear that strike without warning.\nWhat is going on in the body?\nThe body has a natural \"fight or flight\" response to danger. When a person perceives some threat or danger, the autonomic nervous system is stimulated. This helps a person escape from danger. During a panic attack, the body's automatic nervous system is triggered for no apparent reason.\nWhat are the causes and risks of the condition?\nWhile the exact cause of panic disorder is unknown, genetics and social factors may play a part. Caffeine, cocaine, and alcohol also may cause the disorder. Panic attacks can be triggered by severe or prolonged stress. This disorder occurs more often in women than men.", "pred_label": "__label__POS", "pred_score_pos": 0.5457839965820312} +{"content": "Care in Chile, as in most Latin American countries, remains largely the responsibility of female family members in informal arrangements with little government support. The analysis of caring for a dependent older person has commonly been approached from the burden of care perspective, focusing on the tasks carried out, the time spent providing care and the negative (burdensome) consequences for the care-giver. This study reveals the daily experiences of family care-givers of older people through a thematic data analysis of 42 interviews with main family carers of an older person as experienced by the carers themselves. Findings highlight the complex nature of care work. Tasks carried out do not necessarily relate to the intensity of the care experience or a negative experience. Care-givers can work long hours providing care and still feel comfortable and find the experience emotionally rewarding. Care-givers might also carry out only a few tasks and experience pressure. The broader social and economic context can generate constraints that make a specific set of tasks easier or harder on the carer, but these contextual factors do not fully explain the experience of care. Relations, and particularly those that carry an emotional component such as the carer-older person, carer-siblings and carer-spouse, must be considered alongside the tasks and the difficulties or potential constraints of the context to understand the care experience.", "pred_label": "__label__POS", "pred_score_pos": 0.9722689986228943} +{"content": "The amber list is gone!\nFrom October 4 the traffic light system will change completely, with the amber list set to disappear entirely. From that date onwards we can expect a simpler system, with pricey PCR tests no longer required for those travelling to countries like Spain and Italy.\nPreviously, countries had been categorised according to the risk they posed – whether that be from new strains of Covid-19 or a prevalence of existing strains. These classifications followed a traffic light system – green, amber and red.\nBefore returning from an amber country people were required to complete a passenger locator form and take a PCR test. Additionally, it was necessary to take a test on the second day upon returning to the UK. These rules applied to passengers who had had both Covid-19 vaccinations and could provide proof of those vaccinations.\nThose rules are now changing. Now countries will only be categorised as either green or red. Those returning from red countries will still need to self-isolate in hotel rooms, whether vaccinated or not. However, those returning from green countries will not be required to take a pre-departure test before returning to the UK if they have received both doses of a Covid-19 vaccine.\nUpon returning from a green country passengers will still be required to take a rapid lateral flow test before day 2, or on 2 day. Additionally, the following countries will be removed from the red list on September 22 and added to the green list: Turkey, Kenya, Pakistan, the Maldives, Egypt, Sri Lanka, Oman and Bangladesh. Transport secretary Grant Shapps has confirmed that these new measures will remain in place until the new year, at least.\nHowever, passengers will still need to complete the passenger locator form 48 hours before they leave the country they are visiting. In addition, those who haven’t had both jabs will still need to take a test before coming to the UK and will need to take a PCR test on or before day 2 of returning to the UK.\nIt is important to note that the devolved nations have control of their own rules and regulations when it comes to travel, but you can always consult the government website for the latest advice on travel. Should you have any queries at all concerning international countries then you can contact the embassies of those countries.", "pred_label": "__label__POS", "pred_score_pos": 0.7151152491569519} +{"content": "September 15, 2021 - Small business spending in the second quarter of 2021 surged 32.4 points quarter-over-quarter (QoQ) and 56 points year-over-year (YoY), according to the Visa Small Business Spending Index. Consumer demand also surged in Q2 due to a large-scale rollback of COVID-19-related restrictions, which contributed to small businesses being more comfortable and able to spend. However, part of the rise in spending was due to the elevated inflation rate for inputs that small businesses needed.\nOutstanding balances on Visa small business credit cards rose for the second consecutive quarter, leading the Visa Small Business Borrowing Index to rise 2.5 points QoQ and 1.6 points YoY. Small business borrowing remains far below pre-pandemic levels (down 8.8 points from Q4-2019), mostly due to the large amount of small business relief and government stimulus disincentivizing borrowing from traditional sources. These programs will end in early 2022, which could spur more demand for borrowing from traditional sources if small businesses are able to weather the new Delta variant challenges.\nBoth delinquencies and charge-offs fell drastically in the second quarter. Small business delinquencies and charge-offs are both at an eight-year low. Strong sales and relief efforts have helped a large share of small businesses deleverage and remain current on their card payments. The dissipation of stimulus and relief effects could push these indicators back up next year.\n“The broad-based reopening has led small businesses to feel very empowered to spend. Additionally, the spending has been prudent as small business card delinquencies and charge-offs are at the lowest point since we began tracking them. However, borrowing is proving slow to recover due, in part, to government relief programs filling that role.” Wayne BestChief Economist, Visa Inc.", "pred_label": "__label__POS", "pred_score_pos": 0.5332694053649902} +{"content": "The early months and years of a child’s life are often the most challenging and exciting moments for parents. For those experiencing an autism diagnosis, their lives change overnight. Expectations, hopes, and dreams for their child shift as new expectations and challenges arise. Early intervention programs can make a huge difference in a child’s autism…\nToday, telehealth treatment is becoming a standard type of medical care across the country. For those seeking autism treatment, telehealth offers a stress-free convenient support system from the comfort of home. Many children with autism struggle with social anxiety and prefer to be at home. Telehealth therapy, educational tools, and doctors can free parents from…\nAn autism diagnosis can be one of the most significant challenges a child and their parents undergo. Overnight a family’s life can change. Not only do hopes, dreams, and expectations for your child’s future shift, so does your own parenting. No matter the severity of an autism diagnosis, parents should never go through the journey…\nThe early months of a child’s life are often the most challenging time for parents. However, some children begin struggling with social interactions, and the parent suspects autism. In such cases, an early autism diagnosis can make a world of difference for parents and children with ASD. Autism spectrum disorder (ASD) presents in 1 in…\nIn recent years, awareness of Asperger’s syndrome has increased as more people are diagnosed with this high-functioning type of autism. With Asperger’s syndrome frequently portrayed on television and awareness in the media, there is a greater general understanding of the social skills struggles that face those with Asperger’s. These challenges often present as difficulty understanding…\nAutism spectrum disorder (ASD) covers a wide range of developmental challenges and symptoms. Often it takes time to get a diagnosis of autism, and the process can feel overwhelming for the family because it cannot simply be diagnosed with a blood test. Because of its complexity, it can be hard to understand the different types…\nOne of the first challenges parents face when their child is diagnosed with ASD is finding the proper support and resources for their family. There is a wealth of autism resources, support groups, and therapy programs around the world. However, it can be a challenge finding autism support close to home. Educating yourself and your…\nEarly childhood with an ASD diagnosis can be overwhelming for parents. A parent’s plans for their child’s early years and future can shift instantly with the diagnosis. Parents may feel lost among various autism treatment programs, therapists, and their own feelings. The varied symptoms and needs of a child with ASD can leave parents in…\nAutism spectrum disorder (ASD) presents various symptoms and challenges occurring in learners of any age. A formal autism diagnosis cannot be determined with a simple blood test. Early intervention screenings with doctors and clinicians incorporate behavioral observation and analysis to track a child’s autism symptoms. ASD diagnosis can occur at a milestone check-up in the…\nAutism spectrum disorder (ASD) covers a wide range of symptoms and developmental challenges for young learners. While some struggle with verbal communication, others may have more difficulty reading emotions. Because there are many types of autism, therapy can range from multimodal to a single type of therapy, such as applied behavioral analysis. However, we take…", "pred_label": "__label__POS", "pred_score_pos": 0.6115833520889282} +{"content": "Hyundai Motor launches global campaign, ‘Expecting Generation One,’ to share its vision for achieving carbon neutrality, in line with its commitment made at 2021 IAA Mobility ‘Expecting Generation One’ campaign film depicts mothers around the world who are counting on Hyundai Motor to play a key role in ensuring the sustainability of the planet for future generations Hyundai Motor aims to achieve carbon neutrality in its products and global operations by 2045 through clean mobility, next-generation platforms and green energy\nHyundai Motor Company today launched a global campaign, ‘Expecting Generation One,’ with the online premiere of a short film signalling its commitment to fight climate change and achieve carbon neutrality in order to secure a habitable world for future generations.\nThe campaign reinforces Hyundai Motor’s recent declaration at the 2021 IAA Mobility Show in Germany that it aims to achieve carbon neutrality in its products and global operations by 2045 through clean mobility, next-generation platforms and green energy. Hyundai Motor plans to roll out more customer communications for ‘Expecting Generation One’ throughout the remainder of the year.\nWith this campaign, Hyundai aims to build consensus with customers about the value of planning for future generations. Our action is not just for us living in the present, but also for all future generations, including the ecosystems of our precious planet.\nIn the campaign film, which debuted today on the company’s official YouTube channel (@HyundaiWorldwide) and other platforms, mothers and grandmothers from around the globe are seen and heard conveying their heartfelt wishes for a sustainable world in which future generations of people, animals, plants and ecosystems can thrive together. Vulnerable species, such as whales, elephants and penguins, are featured alongside human mothers from diverse backgrounds, heard with a soundtrack of nature sounds and a mother’s lullaby.\nThe campaign serves to reinforce Hyundai Motor’s pledge to cultivate a sustainable future through a multi-dimensional strategy focused on clean mobility, next-generation platforms and green energy, particularly hydrogen, which Hyundai Motor Group detailed at its recent Hydrogen Wave event.\nAs part of its push for clean mobility, Hyundai intends to expand its leadership in electrification in coming years and is aiming to secure 30 percent of its global vehicles sales with zero-emission vehicles (ZEVs). By 2040, the company expects that battery electric vehicles (BEVs) and fuel cell electric vehicles (FCEVs) will account for 80 percent of its total fleet sales.\nThe company also aims to become a clean mobility provider through its long-term investments in green hydrogen based on renewable energy, Vehicle-to-Grid (V2G) and Second Life Battery Energy Storage Systems (SLBESS).\nAs we advance our efforts in clean mobility and green energy, Hyundai Motor will continue to engage customers through campaigns such as ‘Expecting Generation One’ so that they can be part of the journey and share our vision of Progress for Humanity.", "pred_label": "__label__POS", "pred_score_pos": 0.8586941957473755} +{"content": "Why Maintaining your Insurance is Vital to Your Recovery\nAt Risk Guidance Insurance, we appreciate that many SMEs are struggling to pay the bills during the COVID-19 restrictions. Maintaining your insurance cover, however, is one strategy that can actually help your recovery, resulting in a much brighter future as restrictions slowly begin to ease.\nWhy is Maintaining your Insurance Cover Important?\nThe right type of insurance cover means that your business can cope with any potential emergencies that might occur, whether accidents, criminal activity or natural disasters.\nMany business owners, however, may be second-guessing their current policies. They may be wondering whether their policies are still relevant, given the imposed restrictions wrought by the ongoing COVID-19 pandemic.\nThis is a very astute question, which demands an honest answer. This answer is that some of your insurance policies may not be as relevant now as they were prior to COVID-19. Subsequently, this means that your insurance policies need to be reviewed and possibly, revised to suit your new operating conditions.\nWhile you might be tempted to cancel your policies at this time, just imagine the intense financial pressure you may face if disaster strikes without the protection of insurance.\nTwo Insurance Policies that are Vital for your Business\nWhilst your insurance policies are essential for protecting your business, there are two key policies that some SME owners might be questioning during the pandemic. These are Public Liability and Property insurances.\nThese two policies are still essential, because even though you might not be trading at the moment, a pipe could still burst and flood neighbouring buildings or a fire could devastate your leased warehouse, showroom, restaurant or retail outlet. If any of the events occur, even if you are not trading at the moment, and your policy has lapsed, the financial consequences can be dramatic. Now is not the time to maximise your exposure to these risks.\nHow are SMEs Responding to the Pandemic?\nAt Risk Guidance Insurance, we have had very few instances where an SME has actually cancelled their insurance policies. We have also seen a gradual increase in enquiries, from a low around Easter at the height of the pandemic, returning to pre-pandemic levels as restrictions ease. These figures tell us that whilst initially, some SMEs reacted to their lost revenues by cancelling their policies, the vast majority have continued to weather the storm and maintained their policies. This is despite suffering significantly reduced revenues.\nCancelling or reducing your insurance cover can be a big risk at any time, let alone in today’s pandemic environment. This is why we encourage all consumers to contact us to discuss their circumstances. Together we can review your policies, in light of your operational changes, and ensure that your business continues to operate safely with the right type of insurance cover.\nGeneral Advice Warning General Advice Warning The information provided is to be regarded as general advice. Whilst we may have collected risk information, your personal objectives, needs or financial situations were not taken into account when preparing this information. We recommend that you consider the suitability of this general advice, in respect of your objectives, financial situation and needs before acting on it. You should obtain and consider the relevant product disclosure statement before making any decision to purchase this financial product.", "pred_label": "__label__POS", "pred_score_pos": 0.6163761615753174} +{"content": "The Earth Science Literacy Initiative is holding a 12-day online conference starting May 12 to establish the “Big Ideas” and supporting concepts that all Americans should know about Earth sciences. Joaquin Ruiz, a geoscientist and dean at the University of Arizona, is a member of the organizing committee.\nThe group's motivation is that,\n\"Critical decisions involving Earth science are continuously made within the political and educational realms, with significant impacts on all American citizens.\"\n\"The research community must do a better job of helping the public understand the most important concepts emerging from geoscience research. However, understanding scientific discoveries requires a science-literate population.\"\n\"Unfortunately, we also live at a time when there are strong movements that seek to discredit the discoveries of scientific research. Whether acting out of fear, misunderstanding or malice, these movements often portray the healthy debate of scientific inquiry as confusion and a lack of agreement. An individual or set of individuals pushing certain self-serving agendas can almost always find a quote or viewpoint that backs their idea. Many of the foundations of our sciences, such as the age of the Earth, radioactive decay, biological and planetary evolution, climate change, and even the existence of plate tectonics, are discredited and ridiculed by extracting fragmented quotes from prominent scientists and taking them out of context.A deep schism is opening up within our country: at the same time that tremendous scientific advances are being made, increasing percentages of Americans are refusing to believe them.\"", "pred_label": "__label__POS", "pred_score_pos": 0.7290359735488892} +{"content": "The approaches proposed in the literature, such as LeSS and SAFe, are typically based on a multi-level model, with operational work taking place on the lower level and coordination on the upper levels. LeSS, for example, aims to minimize overhead. Here, the operational teams send representatives to the upper level teams and the Scrum process is only modified slightly. SAFe, which is currently the most widely used approach, introduces a total of three levels and numerous new roles and events.", "pred_label": "__label__POS", "pred_score_pos": 0.9999919533729553} +{"content": "On August 29, 2021, Hurricane Ida made landfall at Port Fourchon, Louisiana. The storm, later determined to be one of the largest in U.S. history, tore through the South with 150 mph winds and several inches of downpour. Thankfully, the National Hurricane Center had a forecast and an accurate understanding of the hurricane’s path days in advance. Residents and businesses alike had plenty of time to prepare, evacuate, and avoid harm.\nWhether they\ndid so is another story entirely.\nOne vessel, the\nTriton Hedron, was docked at Port Fourchon days before Hurricane Ida arrived. The vessel was owned by Triton Diving Services, who was contracted with Pharma-Safe Industrial Services by Talos Energy for offshore drilling in the Gulf of Mexico. One of the crew members, an employee of Pharm-Safe, was acting as the vessel’s safety man when they heard that Hurricane Ida was days away. However, instead of evacuating, the captain of the Triton Hedron (acting under Triton’s orders) requested that the crew remain on board.\nThe captain and all the companies involved received multiple advisory warnings that a life-threatening storm was coming, up to the morning that Hurricane Ida was forecasted to arrive. They did nothing. The crew, including the safety man, were ordered to remain on the ship.\nWithin hours, the vessel was ripped away from the port and blown six miles out to sea. Without power, the vessel was rocked and battered by enormous swells and violent gusts. Inside the ship, crew members were thrown about\nfor three hours. The ship nearly capsized. Eventually, the crew was able to regain control of the vessel and took it back to shore, but not without paying a steep cost. Permanent & Lifelong Harm Caused by Triton, Pharma-Safe & Talos Energy\nOur Jones Act attorneys have filed a lawsuit for the vessel’s safety man, who was employed by Pharma-Safe and hired by Triton. His experience during the hurricane was nothing short of catastrophic. After three hours at the mercy of one of the largest storms in U.S. history, our client suffered severe mental and physical injuries, including serious damage to his head, neck, back, and legs. The traumatic experience has left him physically and mentally incapable of offshore work ever again, which in turn has disrupted the rest of his life.\nThe suit has been filed against Talos Energy, Pharma-Safe, and Triton, who all bear responsibility for the harm our client has endured. All of them were responsible for keeping the crew safe and the vessel in seaworthy condition. They all failed on both counts. We look forward to helping our client hold them accountable for the deep losses he’s suffered as a result of their negligence.\nThe suit was filed in Harris County, Texas.", "pred_label": "__label__POS", "pred_score_pos": 0.5974291563034058} +{"content": "Leaving water bottles in your car is a bad idea.\nHave you ever left a plastic water bottle in the car on a hot day? Many of us do it all the time without thinking twice about it.\nHowever, firefighters and other safety advocates are warning drivers that this seemingly innocent act can actually create a serious fire hazard.\nStations battery technician Dioni Amuchastegui shared in a Facebook video that this dangerous incident happened to him. According to him, he was eating lunch while sitting in his parked car. Suddenly he noticed that there was smoke inside the vehicle.\nAfter inspecting where it came from, Amuchastegui realized that the fire was caused by his water bottle.\nHe said:\n“I had to do a double take. It was hot enough to start burning a hole through the seat.”\nIt left two little burn marks in his car seat. He tested it again, and a thermometer held up to the bottle registered a temperature of 213°F.\nIt may be surprising to learn that water, which is typically used to put out fires, can lead to flames. A round plastic bottle filled with clear water can act as a lens that concentrates the sun’s energy on a single point, which can then create immense heat where the ray of sun is directed. When it’s exceptionally sunny, that will obviously trigger it even more.\nThe Oklahoma Midwest City Fire Department conducted its own test and concluded that the dangers are very real. They found out that sunlight magnified by a water bottle can reach 250 degrees Fahrenheit.\nSo yes, leaving water bottles in your car is a bad idea.\nSomeone tried to open the door from the outside. Fortunately, she remembered her dad's tip!\n\"You know when they say that kids are natural artists? I think she’s the perfect…\nMeanwhile, in Australia...\nWould you buy this?!\n“Please. She died a few days ago. I cannot lose those photos as well.”\nUnder all the prosthetic makeup is this beautiful woman!\nThis website uses cookies to ensure you get the best experience.", "pred_label": "__label__POS", "pred_score_pos": 0.9111572504043579} +{"content": "STAT3 plays a crucial role in the serotonergic system as a molecular mediator for controlling emotional reactivity. The findings establish a link between the immune system, serotonergic transmission, and affective disorders such as depression.\nResearchers hypothesize vitamin B1 (thiamine) deficiency may play a significant role in dementia associated with alcohol use disorder. It is known iron deposits in the brain contribute to neurodegenerative diseases. Those with AUD have elevated levels of both iron in their blood and thiamine deficiency. Thiamine is vital for maintaining the blood-brain barrier. Thiamine deficiency associated with AUD disrupts the integrity of the BBB, allowing for more iron deposits within the brain and leading to oxidative tissue damage.\nEpisodic exposure to nicotine, caffeine, and amphetamines triggers malfunctions in the fetal brain, specifically affecting the development of the indusium griseum.\nWhen pregnant women consume diets high in polyunsaturated omega-6 fatty acids, an excess of endocannabinoids is produced which overloads the fetus, and impairs healthy brain development.\nThe popular Netflix show \"13 Reasons Why\" has been linked to an increase in suicides in females between the ages of 10 and 19. Researchers said the numbers grew significantly within 3 months of the show's release.\nA new study reports neural activity in the prefrontal cortex reacts as though every experience is brand new, even if the event is similar to ones that have previously occurred. Researchers say this could account for feelings of déjà vu.\nResearchers have identified new subtypes of neurons in the hypothalamus and determined the function of a dopamine neuron.\n1 2", "pred_label": "__label__POS", "pred_score_pos": 0.9521656632423401} +{"content": "Adela Petrovic’s GAUK project entitled “\nIn the face of gentrification: the changing identities of working-class neighbourhoods in the inner-city of Prague” analyses two selected gentrifying inner-city neighbourhoods, Karlín and Smíchov, identifies the changes in the urban physical and socio-cultural landscape, reflects upon their implications, and investigates the identity construction of these changing neighbourhoods.\nAnother project, supported by the START programme, is “\nWhat about your locality? Life-course differences in experiencing and perceiving residential neighbourhoods” with Pavel Frydrych as the principal investigator and Marie Horňáková, Jan Sýkora and Niloofar Ghafouriazar as co-investigators. The project focuses on life-course differences in how residents experience, perceive and are satisfied with their residential neighbourhoods. It aims to approach the topic from perspectives of three population groups in various life-course stages and living in distinct neighbourhood types (children from suburbs, young families from housing estates, older adults from the inner city).", "pred_label": "__label__POS", "pred_score_pos": 0.9949849843978882} +{"content": "This report first examines how standards systems are being applied to landscapes and jurisdictions. It then explores factors that are important to the effective application of sustainability strategies at a landscape level and identifies opportunities to strengthen the role that standards systems can play in implementing those strategies.\nDiscussion paper and webinar on landscape and jurisdictional assurance and claims.\nLandscape, jurisdictional and other regional approaches are gaining momentum as potential tools for scaling-up the sustainable sourcing of commodities. This briefing aims to assist sustainability standards in assessing these new approaches by providing background information and five ‘entry points’ for exploring potential engagement.", "pred_label": "__label__POS", "pred_score_pos": 0.9888066053390503} +{"content": "Article Title Abstract\nThe transition from school to college is a change every student has to make in their pursuit of higher education. The transition phase is a difficult time for many students, especially to the rural students, many of whom are from a disadvantaged background. However, little literature exists in our state and the country on the transition of rural students into higher education, especially on the challenges they face and the coping strategies they have adopted. This qualitative exploratory study, therefore, aims to explore the challenges rural students in Meghalaya faced when making the transition into higher education, along with the strategies they adopted to cope with the challenges. The participants of this study consist of 68 rural students selected by the use of purposive sampling technique and the data was collected by the use of a semi-structured interview schedule. The thematic analysis method was used to analyse the interview transcripts. The study revealed rural students faced two main challenges, which are academic challenges and socio-emotional challenges, and they had adopted task-oriented coping and emotion-oriented coping strategies in coping with these challenges. The study concludes by suggesting that rural students need additional support when making the transition into higher education.\nKeywords\nrural students, transition, higher education, challenges, coping strategies\nPublication Date\n5-24-2021\nCreative Commons License This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 International License. DOI\n10.46743/2160-3715/2021.4759\nRecommended APA Citation\nLyngdoh Nonglait, F., & Myrthong, D. B. (2021). Rural Students Transition into Higher Education in Meghalaya: Challenges and Coping Strategies.\nThe Qualitative Report, 26(5), 1663-1677. https://doi.org/10.46743/2160-3715/2021.4759", "pred_label": "__label__POS", "pred_score_pos": 0.9921359419822693} +{"content": "The future of work is remote, or even better, distributed, an evolution that the Covid-19 pandemic has dramatically accelerated in the past 18 months.\nThese two concepts are fundamentally different. In this essay, I want to highlight the differences between distributed and remote work. I also want to make a case for why distributed organisations are more effective than traditional or remote ones.", "pred_label": "__label__POS", "pred_score_pos": 0.9908323287963867} +{"content": "A team of scientists has developed a method for quickly finding COVID-19 in blood samples, using a deep learning system and a 3D-printed low-cost digital holographic microscope (DHM).\n\"We propose the use of a deep learning cell classification system using the reconstructed phase profiles output from a compact and field-portable shearing digital holographic microscope in the rapid screening of RBCs for COVID-19,\" the researchers explain of the work behind their letter.\n\"Features are extracted from the phase profile of segmented RBCs at each time frame of the reconstructed video data, then input into a bi-directional long short-term memory (Bi-LSTM) network to classify the cells based on their spatiotemporal behavior. The system is capable of successfully classifying between diseased and healthy samples without chemical processing and with fast turnaround times.\"\nThe 3D-printed prototype microscope is based around an off-the-shelf red laser diode, a one-dimensional translation stage, a 40x-magntification objective lens, a glass plate, and a CMOS image sensor. The laser illuminates the blood sample and a magnified image is projected onto the glass plate, forming an interference pattern captured by the image sensor as a video and sent to a computer for analysis.\nThe resulting video is fed into a neural network running on a workstation with an NVIDIA Quadro P4000 graphics processor, which proved capable of classifying a single patient's red blood cells in under 10 seconds — allowing it to quickly detect patients with COVID-19 infections with 80 per cent sensitivity and nearly 93 per cent specificity.\n\"The advantages of the presented system include cost, accessibility, and time to results,\" the researchers note, \"but further investigations with larger patient pools including mild or asymptomatic infections are needed to validate the system performance more rigorously.\"\nThe team's work has been published in the journal\nOptics Letters under open-access terms, with more information available on IEEE Spectrum.", "pred_label": "__label__POS", "pred_score_pos": 0.5962527394294739} +{"content": "Key participant in UK’s first Net Zero power station to collaborate with Navigator Terminals to unlock roadmap for storage and transport of CO2 and hydrogen\n8 Rivers Capital LLC announces memorandum of understanding between subsidiary Zero Degrees Whitetail 1 Ltd and Navigator Terminals to explore potential collaboration across the storage and transport of chemicals, gases and liquids in the UK including CO2, hydrogen and ammonia by ship. This comes in International Shipping Week as global attention turns the push for international shipping emissions to reach absolute zero by 2050, consideration must also focus on the ways in which the maritime sector can contribute towards a low carbon transition.\nUnder the terms of the agreement, the project team will explore the potential for Navigator Terminal’s existing and potential future network of storage assets across the UK to accommodate the growing demand for transport and storage of CO2, hydrogen, and ammonia as part of the wider growth of geological sequestration of carbon emissions. With outstanding supporting infrastructure, including a deep water jetty and rail handling facilities, the Navigator Terminals facility at Teesside is fully integrated into the UK’s largest chemical cluster and can rapidly scale to support deep decarbonisation of these carbon intensive industries.\nAs the UK Carbon Capture and Storage (CCS) progresses through its early stages of development, there is a growing demand for permanent geological storage for CO2 from emitters not co-located near to a suitable storage site. 8 Rivers is leading the development of the initial Net zero emissions power stations in the UK, such as Whitetail Clean Energy. In these projects, nearly all air emissions, including traditional pollutants and CO2, are eliminated and pipeline-quality CO2 is produced so that it can be captured and stored offshore. Produced hydrogen or CO2 or ammonia can then be transferred to a Navigator Terminals location before onward transfer by ship or pipeline to its destination, such as one of the UK carbon storage sites.\nCam Hosie, Chief Executive of 8 Rivers Capital, added of the project: “This partnership signals the latest step in our commitment to support the UK to develop world leading carbon capture capabilities through commercialising innovative power generation projects such as Whitetail Clean Energy, as well as innovative hydrogen technologies, ensuring that near all air emissions are eliminated and pipeline quality CO2 is produced so that it can be captured and stored offshore, for Net Zero emissions . But once the CO2 is captured we need to explore, understand and deliver infrastructure to support these assets to successfully transfer, transport and store CO2 for transport to permanent storage locations. Navigator Terminals is a leading UK terminal operator and has recognised the significant potential of CO2, hydrogen, and ammonia transport in the coming decades.”\nJason Hornsby, Chief Executive Officer for Navigator Terminals said of the partnership: “We are the UK’s leading transport, storage and handling experts for chemicals, gas, biofuels, and fuels and operate a network of strategically located terminals. We are focused on supporting our regions to decarbonise and utilise the highest quality fuels and energy carriers, as part of supporting the UK to reach Net Zero we are adapting to the changing needs of our local industries. We recognise that in the coming decades there will be significant volumes of CO2 to be shipped for storage and this partnership with 8 Rivers forms the first step in understanding and then deploying the infrastructure needed to help the North East meet its decarbonisation goals, creating significant jobs and supply chain benefits in the process.”\nSource: Navigator Terminals", "pred_label": "__label__POS", "pred_score_pos": 0.7221146821975708} +{"content": "Motor vehicle crashes are a leading cause of death among children. While most people believe their children are properly buckled up, the National Highway Traffic Safety Administration, or NHTSA, points out that 46% of all car seats are misused.\nA Child Passenger Safety child seat inspection event will be held on Saturday from 8:30 a.m. to 11:30 a.m. at the Texas Department of Transportation Laredo District Office (covered canopy area in the back of the facility) located at 1817 Bob Bullock Loop. Parents and caregivers with their children are encouraged to attend.", "pred_label": "__label__POS", "pred_score_pos": 0.9816232919692993} +{"content": "Cloud computing provides on-demand services over the internet. These services include server, storage, networking, software, and data analytics services. Due to the cloud’s many benefits, many businesses in the United States leverage the technology in some capacity. In fact, cloud services spending increased to over $18 billion in the first quarter of 2021 alone.\nThere’s also a wide range of cloud services designed for dental practices available today. From dental practice management software to scalable storage solutions and VoIP phone systems, your practice stands to gain a lot by implementing cloud technology.\nHowever, if you’re still on the fence about adopting cloud solutions, we’ve compiled a list of pros and cons that will help you decide.\nThe advantages of cloud computing\nDental practices that incorporate cloud computing stand to gain a host of benefits.\nA simplified IT environment\nThe first benefit of cloud migration is the ability to simplify your business IT. Physical, on-site servers and a complex networking setup are no longer mandatory. With the cloud, all the storage tools and equipment you need are in fully managed off-site data centers that can be accessed with an internet connection.\nThis saves your practice the time and money required to install, configure, and test on-premises infrastructure, along with the effort of hiring and training in-house IT staff. Additionally, cloud solutions are highly scalable. This allows you to only pay for the services and storage you need at any given time, with the option to expand as your practice grows.\nGreater digital security\nProtected storage of patient information is crucial to any dental practice. If you're reluctant to migrate such sensitive data to an off-site data center because of security concerns, you'll be glad to know that cloud solutions typically offer a robust, reliable security system. These platforms come with advanced threat prevention systems, firewalls, encrypted HIPAA-compliant databases, and data backups managed by professionals who monitor everything around the clock.\nThis means you and your staff can rest easy knowing the chances of potential breaches or cyberattacks are significantly minimized. Additionally, having such critical information accessible online further secures your data in the event of hardware damage, power outages, or natural disasters.\nAccess data and applications anytime, anywhere\nAnother reason to move to the cloud is the ability to access and manage your information when and where you please. This is critical for administrative staff who choose to work from home, or dental practitioners who require remote access to patient information in case of emergencies. With all your data online, you can share, edit, and retrieve your files at a moment’s notice.\nThe disadvantages of cloud computing\nWhile there are many advantages to the cloud, dental practices should be aware of some of the risks associated with it.\nRequires a fast and reliable internet connection\nThough the cloud offers a myriad of benefits, you must first ensure a stable, reliable internet connection in order to maintain constant access and meet bandwidth demands. We recommend investing in enterprise-grade networking equipment and internet plans before adopting such platforms. Otherwise, you may face unnecessary disruptions or downtime.\nService level agreements may vary\nWhen sifting through potential cloud providers, have a thorough read of their service offerings. These can vary depending on the company, with some offering a better fit for your practice than others. When weighing out service level agreements, it may help to consider accountability (do they guarantee uptime and system performance?), transitioning (will they help transition your data to another vendor, if necessary?), and the right to cancel.\nPotential hidden fees\nSimilar to assessing the cloud provider’s service package, it’s also important to discuss all fees involved. Avoid exorbitant hidden fees by clarifying all features and procedures upfront. This can help outline all the necessary expectations you have of the vendor, and what they’ll inevitably cost you.\nThough cloud computing isn’t without its challenges, any modern dental practice can benefit from the overwhelming advantages it offers. Manage your data with greater efficiency and flexibility, and join the many practices now adopting the cloud. Enjoy all the benefits of the cloud without the potential pitfalls. Call Pact-One Solutions to migrate to the cloud today.", "pred_label": "__label__POS", "pred_score_pos": 0.6248373985290527} +{"content": "January 10, 2020\nWe urge the State to commit to combating homelessness for the tens of thousands of women raising their children inside homeless shelters in New York City. Ending the crisis of family homelessness requires bold solutions and the State must do its part to ensure the 70% of shelter residents who are women and children have a viable pathway towards housing stability. To do this, the State must expand rental assistance and transitional housing supports for families experiencing homelessness, and ensure that survivors of domestic violence, the leading cause of family homelessness, have access to critical preventive and permanent housing services to keep them and their children stably and safely housed.", "pred_label": "__label__POS", "pred_score_pos": 0.9956603646278381} +{"content": "(Helsingin yliopisto, 2021)\nRecently, mutations in the SGMS2 gene were shown to result in a rare disease known as osteoporosis with calvarial doughnut lesions. Affected patients present with severe, early-onset osteoporosis or skeletal dysplasia depending on the underlying mutation. In addition to the skeletal manifestations, patients also exhibit neurological symptoms, most commonly transient, spontaneously remitting, and recurring cranial nerve palsies. Similar neurological characteristics have previously been described in another rare condition known as Melkersson-Rosenthal syndrome (MRS).\nThe objectives of this thesis were to provide a comprehensive review of literature on the role of sphingomyelin (SM) metabolism in the skeletal and central nervous systems and characterize the nature and prevalence of SGMS2 variants in cohorts of 14 Finnish MRS patients and 47 Finnish primary osteoporosis patients.\nThe literature review explores the currently available data on SM metabolism in basic and clinical research. In bone, SM is suggested to hold a key role as a source of inorganic phosphate needed during mineralization and several studies have shown that aberrant SM metabolism leads to defective bone mineralization. In the central nervous system, SM metabolism has been shown to be altered in various pathologies, though the underlying pathophysiological mechanisms and their significance remain elusive.\nGenetic analyses of the cohorts were performed by extracting DNA from the patients’ whole blood, amplifying the coding and noncoding regions of the SGMS2 gene with PCR and using capillary sequencing to read the genetic code. Altogether 13 discrete single nucleotide variants were found, of which one was a missense variant present in two patients. The variant is relatively rare, has a high CADD score and is predicted probably damaging by computational software. The medical records of the two patients revealed nothing significantly deviating from the cohort norm.\nThis thesis establishes that SGMS2 variants are not a common cause of primary osteoporosis or MRS in these two cohorts of Finnish patients. The significance of the identified missense variant warrants further studies.", "pred_label": "__label__POS", "pred_score_pos": 0.5033692717552185} +{"content": "Hometown: Pittsburgh, PA Education: Temple University, 2018 | Strategic Communication with a concentration in Rhetoric and Public Advocacy Job: Litigation Associate – Ballard Spahr, LLP Program: Full-Time Day Life at Temple Law\nDuring my time at Temple Law, I was an active member of the Black Law Students Association and Temple Law Review. I also served as a teaching assistant for a first-year contracts course.\nAs the Vice President of the Black Law Students Association, I was able to contribute to and benefit from an active community that centered issues of race and social justice. BLSA created an environment where members felt relief from the daily stress of law school. I will certainly miss the general body meetings, but I look forward to returning as a member of the alumni. I joined Temple Law Review as a Staff Editor and was later chosen to be Editor-in-Chief of Volume 93. Together, these experiences provided the opportunity to work closely with dozens of exceptional students who spotted flaws in our legal system and were determined to address them. My time on Temple Law Review sharpened my legal research and writing skills, introduced me to various areas of law, and ultimately made me a better leader. While I am appreciative of my Temple Law Review predecessors, I am particularly grateful to the members of Volume 93, each of whom dedicated countless hours to making the journal the best it could be. Advice from a Graduate\nThere are two pieces of advice I would like to share with incoming students. First, know that you are not on this journey alone. Whenever you need support, lean on your community, including the faculty and administrators at Temple Law. There are people rooting for you every step of the way, and they are eager to help if given the opportunity to do so. It takes a village, and you have one here at Temple Law. Second, extend yourself grace. Law students are often their worst critics. You did not make it to law school by chance. You are worthy of your place in the Temple Law community and will do great things, regardless of the challenges you will inevitably face along the way.\nA Lasting Impact\nMentorship is invaluable. Throughout my time at the law school, I had the pleasure of mentoring first- and second-year students while also being mentored by those who have come before me. As a first-generation college and law student, mentorship played a crucial role in my academic and professional success. I look forward to continuing to pay it forward—lifting as I climb.\nTemple Law Lessons\nTake care of yourself. It is easy to lose track of your health and wellness if you do not make them a priority. Check in with yourself regularly and ensure you are pouring into your mental, physical, and emotional well-being just as often as you are pouring into your academic and professional endeavors. You can grab dinner with your friends, watch your favorite show, and still do great in law school. Success is much harder to achieve when you abandon the aspects of life that bring you peace and comfort.", "pred_label": "__label__POS", "pred_score_pos": 0.6774531602859497} +{"content": "SUMMARY\nObjectives: The case report describes a minimally invasive, multidisciplinary approach to a single discolored anterior tooth, with internal bleaching using traditional Japanese paper (Washi), a gingivoplasty with a three-dimensional (3D) printed surgical guide, and ultrathin feldspathic porcelain veneers.\nClinical consideration: The patient’s primary concern was improving her smile. After clinical evaluation, internal tooth bleaching for the discolored tooth and gingivoplasty with restoration of the maxillary anterior six teeth and first premolars was recommended. The internal tooth whitening was accomplished with sodium perborate mixed with 30% hydrogen peroxide impregnated in Washi and sealed in the root canal with glass ionomer. Once the tooth bleaching was completed, the 3D printed surgical guide was placed in the patient’s maxillary anterior region and used to guide soft tissue recontouring. After 6 months, ultrathin feldspathic porcelain veneers were placed.\nConclusion: Well-planned restorative procedures combining internal tooth bleaching using Washi, gingivoplasty performed with electrosurgery using a 3D printed surgical guide, and ultrathin feldspathic porcelain veneers can achieve the desired results in the esthetic zone and remain successful for 4 years.\n©Operative Dentistry, 2021", "pred_label": "__label__POS", "pred_score_pos": 0.6510735750198364} +{"content": "Knowledge of habitat use by top marine predators in response to environmental conditions is crucial in the current context of global changes occurring in the Southern Ocean. We examined the at-sea locations of male Adélie penguins (Pygoscelis adeliae) breeding at Dumont d’Urville during their first, long incubation trip. Compared with the chick-rearing period, penguins performed longer trips, going to oceanic waters as far as 320 km from the colony. We observed 3 strategies: (1) five individuals covered large distances to the north, targeting open-ocean areas and following the currents of two persistent eddies; (2) five individuals foraged to the north-west, close to the Antarctic shelf slope at the limit of the pack ice; and (3) three individuals covered much shorter distances (northwards or eastwards). The foraging range also seemed to be limited by the body condition of the penguins before their departure to sea.", "pred_label": "__label__POS", "pred_score_pos": 0.9748451113700867} +{"content": "In Marcus P. Adams, Zvi Biener, Uljana Feest & Jacqueline Anne Sullivan (eds.),\nEppur Si Muove: Doing History and Philosophy of Science with Peter Machamer: A Collection of Essays in Honor of Peter Machamer. Springer (2017)\nAuthors Abstract\nDo neurobiologists aim to discover natural kinds? I address this question in this chapter via a critical analysis of classification practices operative across the 43-year history of research on long-term potentiation. I suggest that this 43-year history supports the idea that the structure of scientific practice surrounding LTP research has remained an obstacle to the discovery of natural kinds as philosophers of science have traditionally conceived them.\nKeywords No keywords specified (fix it) Categories No categories specified\n(categorize this paper)\nBuy the book Find it on Amazon.com DOI 10.1007/978-3-319-52768-0_9 Options Download options References found in this work BETA\nNo references found.\nCitations of this work BETA\nNo citations found.\nSimilar books and articles\nLong-Term Potentiation: One Kind or Many?Jacqueline Sullivan - 2016 - In\nEppur Si Muove: Doing History and Philosophy of Science with Peter Machamer, A Collection of Essays in Honor of Peter Machamer. Springer Verlag. pp. 127-140.\nLong Term Potentiation and CaM-Sensitive Adenylyl Cyclase: Long-Term Prospects.Warren Heideman - 1995 -\nBehavioral and Brain Sciences18 (3):477-478.\nLong-Term Potentiation: Does It Deserve Attention?Shane M. O'Mara, Sean Commins, Colin Gemmell & John Gigg - 1997 -\nBehavioral and Brain Sciences20 (4):625-626.\nMechanisms Underlying Induction and Maintenance of Long-Term Potentiation in the Hippocampus.M. A. Lynch - 1989 -\nBioessays10 (2-3):85-90.\nConcepts Structured Through Reduction: A Structuralist Resource Illuminates the Consolidation – Long-Term Potentiation (Ltp) Link.John Bickle - 2002 -\nSynthese130 (1):123 - 133.\nAcute Inhibition of Estradiol Synthesis Impacts Vestibulo-Ocular Reflex Adaptation and Cerebellar Long-Term Potentiation in Male Rats.Jacqueline Anne Sullivan & Roberto Panichi Cristina V. Dieni, Aldo Ferraresi, Jacqueline A. Sullivan, Sivarosa Grassi, Vito E. Pettorossi - 2018 -\nBrain Structure and Function223 (2):837-850.\nDo the Calmodulin-Stimulated Adenylyl Cyclases Play a Role in Neuroplasticity?Zhengui Xia, Eui-Ju Choi, Daniel R. Storm & Christine Blazynski - 1995 -\nBehavioral and Brain Sciences18 (3):429-440.\nLong-Term Potentiation: Enhancing Neuroscience for 30 Years.Timothy Bliss, Graham Collingridge & Richard Morris (eds.) - 2004 - Oxford University Press UK.\nEngaging Employees for the Long Run: Long-Term Investors and Employee-Related CSR.Alexandre Garel & Arthur Petit-Romec - forthcoming -\nJournal of Business Ethics:1-29.\nRepetition Priming: Memory or Attention?Peter M. Milner - 1997 -\nBehavioral and Brain Sciences20 (4):623-623.\nLong Term Epistemic Actions.Mark-Oliver Casper - 2017 -\nAvant: Trends in Interdisciplinary Studies8 (1):119-130.\nLong-Lasting Potentiation of GABAergic Inhibitory Synaptic Transmission in Cerebellar Purkinje Cells: Its Properties and Possible Mechanisms.Masanobu Kano - 1996 -\nBehavioral and Brain Sciences19 (3):354-361. Analytics Added to PP index\n2021-08-31\nTotal views\n0\nRecent downloads (6 months)\n0\nHow can I increase my downloads?\nDownloads Sorry, there are not enough data points to plot this chart.", "pred_label": "__label__POS", "pred_score_pos": 0.5305864810943604} +{"content": "Sign up for the PPE Prospective Majors email list to receive emails about upcoming PPE events.\nIn a world where people are increasingly asked to employ tools that cut across disciplines, the PPE major offers an interdisciplinary education that combines broad and rigorous training in the foundations of our allied disciplines\n. Apart from taking some basic courses in Psychology, Philosophy, Politics, and Economics, each PPE major is required to specialize in a concentration of their choice. Each concentration tends to focus a bit more on a subset of the four constituent PPE disciplines: psychology, philosophy, economics, or political science. For example, students choosing the Distributive Justice concentration will focus on both factual and evaluative questions about the existence and working of just institutions, and what obligations individuals or groups have toward one another. Distributive Justice focuses more on Political Philosophy, though students are encouraged to take courses in legal studies, politicial science and economics that bear on questions of distributive justice. Students choosing the Choice and Behavior concentration, by contrast, will tend to focus more on modeling, explaining, or predicting individual and social behavior, and are encouraged to include classes in Psychology, Economics, but also Sociology and Political Science.\nSince inception at Penn, PPE has been popular and today it is one of the largest majors in the College of Arts and Sciences. The major is intended to prepare its graduates for careers as diverse as public policy, consulting, business, journalism, law, and international affairs, among others. It is an excellent pre-law major and it also offers suitable preparation for graduate study in any of the constituent disciplines. As you explore your major options, take the time to consider how you might be interested in focusing the major and the kinds of opportunities a PPE major affords.\nHaving a chat about PPE\nStudents interested in having a conversation about PPE are encouraged to make an appointment with PPE's Associate Director.\nYou can talk to current majors both through:\nthe University's Major Advising Programor by reaching out to current members of PPE's Undergraduate Advisory Board.", "pred_label": "__label__POS", "pred_score_pos": 0.66507887840271} +{"content": "We provide a full range of services to ensure your business-critical engineering systems remain functional, safe, compliant and efficient. We tailor our offering to meet your specific needs, covering everything from electrical testing and repairs, lighting maintenance and energy solutions, to water treatment, climate control and fire protection.\nWe provide a full range of planned preventative maintenance (PPM) services that ensure your buildings and assets remain operational, fully compliant with legislation and environmentally efficient. This involves both:\n• time-based preventative maintenance – based on a regular calendar of inspection, repair and replacement\n• condition-monitored maintenance – based on monitoring condition and performing the right maintenance to prolong asset life.\nOur contracts span mechanical and electrical (M&E), heating, ventilation and air conditioning (HVAC), and building fabric maintenance.\nOur HVAC engineers are specialists in controlling the temperature of your building and ensuring adequate ventilation. With expertise in monitoring, repairing and prolonging the life of boilers, air conditioning units, ducts and moisture vents, we will ensure that your inter-related air control systems are functioning efficiently and creating a comfortable, healthy environment.\nAs part of any new contract, we can provide a full Asset Registration and Plant Dilapidation Report. This gives you a clear view of the current condition of all your plant and equipment, to assist with budget forecasting.\nOur reports cover heating, ventilation and air conditioning, electrical distribution systems, fire and security systems, building management systems, public health (including water treatment), building fabric services, roofing and drainage, handyperson services, and subcontractor management.", "pred_label": "__label__POS", "pred_score_pos": 0.5998462438583374} +{"content": "This event has passed. COVID and Care: Hope and Caution After (?) the Pandemic October 14 @ 4:00 pm - 5:30 pm CDT\nCaring for someone living with dementia during the COVID-19 pandemic adds unique challenges for caregivers. This program provides simple tips caregivers can put in place whether the person living with dementia lives at home, in a residential facility, or care providers are coming into the home.\nParticipants will review existing knowledge related to COVID and people with dementia, explore potential mental health concerns related to prolonged isolation and entering a “post-pandemic” world, and discuss emerging research and trends related to COVID-19 outcomes in people with and without dementia. This program is led by G.J. Hodson, MA, researcher, former dementia caregiver, and current Alzheimer’s Association volunteer.\n1.0 CEU will be provided to social workers, licensed professional counselors, and registered nurses at no charge.\nRSVP: https://bit.ly/3ozU43P", "pred_label": "__label__POS", "pred_score_pos": 0.9557783603668213} +{"content": "Details Year: 2021 Published in: Scandinavian Journal of Management Cited as: Sudhir Rama Murthy, Kate Roll, Alastair Colin-Jones, Ending business-non-profit partnerships: The spinout of social enterprises, Scandinavian Journal of Management, Volume 37, Issue 1, 2021, 101136, ISSN 0956-5221, https://doi.org/10.1016/j.scaman.2020.101136. Subject\nText here…\nAbstract\nBusiness-non-profit partnerships are expected to create sustained impact, yet they often remain temporary or episodic. By using relationship ending theory and drawing on partnership types from Austin and Seitanidi (2012a), we explore the termination of business-non-profit partnerships and connect how partnerships end to their potential long-term impact. Specifically, we ask: How and why do business-non-profit partnerships end? And, what is the relationship between partnership type and partnership endings? Through interviews and focus groups, we identify two partnership endings: ‘exit’ and ‘spinout.’ The former is the expected severance of ties due to dissatisfaction or the accomplishment of an intended outcome. The latter is more intriguing. As illustrated through two case examples, successful partnerships can create financially self-sustaining social enterprises that continue tackling the chosen problems independently. We argue that spinning out a social enterprise offers a pragmatic pathway that precludes deeper integration between partners – contrary to what is often proposed in the partnership literature – and is best understood as a relationship ending process.\nPaywall\nVisit the journal website to see access options for this document.", "pred_label": "__label__POS", "pred_score_pos": 0.7008093595504761} +{"content": "To ask the Secretary of State for Foreign and Commonwealth Affairs, what his policy is on the export of (a) arms and (b) crowd control devices to overseas governments that his Department has classified as (i) non-democratic and (ii) oppressive.\nAnswered on\n17 March 2020\nRisks around human rights violations or abuses form a core part of the assessment of export licence applications, and are a key factor in the approval or denial of a licence. We do not export equipment where we assess there is a clear risk that it might be used for internal repression. A careful assessment of equipment, potential end use and end user is central to the assessment process. When making assessments, we draw on a range of sources including the media, international organisations, our diplomatic posts, from across Government and reports from our overseas networks.", "pred_label": "__label__POS", "pred_score_pos": 0.9901256561279297} +{"content": "According to a new survey, women and Black, Indigenous and People of Color (BIPOC) respondents report lower feelings of safety and privacy online than men and white respondents. The “Demographics of Cybercrime” report, presented by Malwarebytes in partnership with non-profit Digitunity, asked 5,000 people across the United States, United Kingdom and Germany about their perceptions and experiences of being online.\nA sense of safety and privacy online\nOf all respondents, 50% reported not feeling private online, while 31% reported not feeling safe. Breaking down those statistics, the report notes that while 47% of men reported feeling either “somewhat safe” or “very safe” on the internet, only 37% of women felt the same. Thirty-eight percent of BIPOC respondents reported feeling “somewhat safe” or “very safe,” compared to 44% of white internet users.\nWhen it comes to privacy, white and BIPOC respondents reported similar rates of feeling that their information is private online (29% compared to 28%, respectively). However, 26% of women reported feeling that their information is private online, compared to 32% of men.\nWomen and BIPOC respondents at higher risk of being hacked\nThe survey asked respondents to list which suspicious online activities they had encountered in the past.\nSpam text messages:Seventy-six percent of overall respondents had received text messages from unknown numbers instructing them to click on a link. Women reported higher rates of this activity, with 79% of women having received a spam text, compared to 73% of men. Social media hacks:While 40% of white internet users reported having their social media accounts hacked, 45% of BIPOC respondents reported experiencing such a hack. 46% of women reported that their social media had been hacked, compared to 37% of men. Identity fraud:Twenty-one percent of BIPOC internet users reported having had their identity stolen. Only 15% of white respondents said that their identity had been stolen online.\nOverall, women experienced a slightly higher rate of suspicious online activity than men (33% compared to 30% of respondents).\nMen report higher awareness of cybersecurity tools\nThe survey asked respondents about their familiarity with various cybersecurity resources, including anti-virus protection, virtual private networks (VPNs), identity protection or monitoring, digital vaults and password managers. Across all methods of protection, women reported familiarity with the tools less often than men.\nFor access to the full report and analysis, click here.", "pred_label": "__label__POS", "pred_score_pos": 0.6484754085540771} +{"content": "Through his contribution to poetry, Robert Browning is one of the most well-known and significant poets and playwright of the Victorian era. Having lived between the years 1812 and 1889, Browning died at the ripe age of seventy-seven years old. Browning’s history indicates that he used to be born into a middle-class family where his father, Robert Browning, was a clerk with a giant wage while his mother, Sarah Anna, was a talented musician. Sarianna Browning, Robert Browning’s youthful sister, was also talented in exclusive arts. Browning’s father had an interest in literature and was, therefore, an avid literature collector and encouraged his children to pursue literature and different forms of art. As a result, Browning had a firm foundation in art and literature.\nIn his early years, Browning’s father hired Italian grammarian Angelo Cerrutti to tutor Browning and his sister Sirianna. As a result, this tutor initiated Browning’s relationship with Italy which would later shape most of his works (Mukherjee 614). Most notable of Browning’s friends and acquaintances who helped develop his poetry into focus include Charles Dickens, Rev. W.J. Fox, Alfred Dommett, John Forster, and Harriet Martineu (Hawlin, 45). These individuals are just but a few who shaped Browning’s development into literary stardom.\nPoets and authors’ successes are distinguished their acclaimed works. To know Romeo and Juliet and other plays is to understand Shakespeare. It is no different on the part of Robert Browning. Some of his globally acclaimed works include The Ring and the Book, Men and Women, My Last Duchess, and the Parleyings with Certain People of Importance in Their Day. Most of the poems in various works are famously monologues.\nDespite his renown success in poetry, Robert Browning struggled to establish himself as a renown poet. However, one of the most significant influences on Robert Browning’s poetry and writing was his wife, Elizabeth Barrett Browning. Elizabeth Barrett, was an acclaimed poet who, incidentally, was Browning’s senior regarding age. Barret acclaim was significant as she was one time considered for the Poet Laureate (Stott and Avery 7). Having read her poetry, Browning corresponded with Elizabeth through letters from which, romance ensued. The couple later married against Elizabeth’s father’s wishes and relocated to Italy due to her poor health. As a result, Elizabeth is credited for her influence on Robert more so in the collection Men and Women which Robert dedicated to her. Robert Browning’s success in poetry begun after his marriage to Elizabeth and increased even after her death.\nBrowning’s’ relocation to Italy was very influential to his writing because there is the abundant presence of Italy in many of his works. In various works credited to him, most of the characters in works such as Men and Women and My Last Duchess present Italian personas with Italian socio-cultural backgrounds. The names such as Alfonso and Filippo Lippi indicate his continued relationship and influence with Italy (Sinfield 1). Despite being well-traveled in other areas such as France, Italian influence is dominant and is equitable to the English influence on Browning’s works.\nDespite the Italian influence on his works, the social and cultural organization of Victorian society remained a significant influence on his works. Politically, Browning can be argued to be a liberal left leaning of his time. In some of his poems, it is evident that he was against slavery and supported abolition, was in support of the North in the American Civil war, championed women emancipation, and characteristically ought for animal rights (Woolford, and Karlin 157). Furthermore, he was characteristically absent in the Victorian Society support and glorification of war. From the various observations, it is evident that Browning was very ahead of his time.\nFrom the various pieces of literature, it is evident that Browning engages in dramatic monologue. This aspect of writing and contribution to the Victorian era literary scene distinguishes Browning as one of the influential playwrights (Sinfield 1). The notable tools that he uses in his monologues include diction, symbolism, and rhythm. Consequently, his success in this mode of poetry writing influenced other poets such as the notable twentieth-century poets such as Robert Frost and T.S. Eliot. In the aspect of dramatic monologue, Browning uses single characters in poems whose speech comprises of the whole poem. The primary aim of this form of the literary method is to enable the reader to understand the personality, feelings, and temperament of the speaker in the poem about a specific social setting and history. Dramatic monologues draw the audience into the head of the speaker. In My Last Duchess, Browning brings the audience into the mind of Alfonso II, Duke of Ferrara. From the poem, one can easily observe that the duke is self-centered, arrogant, and conceited.\nIn conclusion, it is evident that Robert Browning is a successful Victorian-era poet. Notable influences to his works include his father, Robert Browning, who initiated him to the literary scene, his tutor Angelo Cerrutti, and most notably his wife, Elizabeth Barrett Browning. His encounters in Italian and English societies form a critical influence in most of his works. Politically, Browning can be argued to be a liberal who is left-leaning due to his modern views on different issues. His main contribution to the Victorian era poetry is dramatic monologue which is evident from works such as My Last Duchess.\nWorks Cited\nHawlin, Stefan. Robert Browning. Vol. 10. Routledge, 2012.\nMukherjee, Baidehi. “Contextualizing the Italian Influence in Reading Robert Browning’s Men and Women and The Ring and The Book.” LandLit, vol.2, no.2, 2015, pp.612- 621.\nSinfield, Alan. Dramatic Monologue (Routledge Revivals). Routledge, 2014.\nStott, Rebecca, and Simon Avery. Elizabeth Barrett Browning. Routledge, 2014.\nWoolford, John, and Daniel Karlin. Robert Browning. Routledge, 2014.", "pred_label": "__label__POS", "pred_score_pos": 0.5678839087486267} +{"content": "Canada-based company Stantec’s IT hiring declined 7.5% in August 2021 when compared with the previous month, according to GlobalData’s Job Analytics database.\nThe company’s overall hiring activity increased by 4.12% in August 2021 when compared with July 2021.\nIT jobs claimed a 10.08% share in the company’s total hiring activity in August 2021, and recorded a 6.95% decline over the last three-month average share.\nSoftware and Web Developers, Programmers, and Testers tops Stantec IT hiring in August 2021\nOut of the total IT job titles posted by Stantec, Software and Web Developers, Programmers, and Testers emerged as the leading occupation, recording a share of 39.66% in August 2021, and a 360% rise over July 2021, while Computer and Information Analysts claimed a share of 27.59% in August 2021, and registered growth of 300%. Miscellaneous Computer Occupations held a share of 22.41% in August 2021, a 44.44% rise from July 2021.\nNorth America drives IT hiring at Stantec\nNorth America emerged as the leading region in the global construction IT hiring activity in August 2021 with a 72.41% share, which marked a 44.83% rise over the previous month.\nAsia-Pacific stood next with 13.79%, registering a 166.67% month-on-month growth. Europe was the third leading region with a 10.34% share and a 200% rise over July 2021.\nIn the fourth place was Middle East & Africa with a share of 3.45% and a month-on-month increase of 100%.\nThe US commanded a leading presence in the region’s construction industry IT hiring activity with a 36.21% share in August 2021, a 31.25% growth over July 2021. Canada featured next with a 36.21% share, up 61.54% over the previous month. The UK recorded a 10.34% share, an increase of 200% compared with July 2021.\nJunior Level jobs lead Stantec IT hiring activity in August 2021\nJunior Level jobs held a share of 70.69%, up by 141.18% from July 2021. Mid Level positions with a 17.24% share, a decline of 23.08% compared with the previous month.\nIn the third place was Entry Level job ads with a 12.07% share, up 40% over July 2021.\nMethodology:\nGlobalData’s unique Job analytics enables understanding of hiring trends, strategies, and predictive signals across sectors, themes, companies, and geographies. Intelligent web crawlers capture data from publicly available sources. Key parameters include active, posted and closed jobs, posting duration, experience, seniority level, educational qualifications and skills.", "pred_label": "__label__POS", "pred_score_pos": 0.8226882219314575} +{"content": "In the UK insurance industry, customer outcomes and pricing are under the spotlight. This eBook focuses on how insurers can prepare for the era of customer-centric insurance by addressing price walking and taking a more proactive approach to pricing to achieve a competitive edge.\nWhile there has been plenty of talk about the FCA’s new rules on pricing and the reporting of value measures data, little of it has focussed on the sale of ancillary products or “add-ons”. This blog highlights how ARAG has engaged with the FCA to reduce the burden on brokers.\nRecently, the FCA spotlight has turned to the insurance sector, focusing on CASS 5 obligations and client money calculations. This paper explores the key CASS 5 requirements, as outlined in the FCA’s handbook and other CASS regulations that affect firms operating within the insurance sector.\nThis blog highlights how the challenges created by the FCA ruling on fairness in pricing should lead many general insurers to accelerate how they innovate with new products and services that offer greater value to all their customers.\nFrom 31 March 2021 the scope of SMCR requirements was extended to cover conduct training and breach reporting for all staff. Sicsic Advisory’s Nindy Mellett highlights how insurance brokers can embed new conduct rules for better business.\nThe FCA’s final report on its market study into general insurance pricing practices proposes several reforms to ensure fair value for customers. In this webinar, an expert panel discuss what the future holds for insurance pricing and how insurers can adapt by adopting different pricing techniques.\nRecent commentary and media coverage about the FCA’s business interruption insurance test case has hit the reputation of the insurance profession. The Society of Insurance Broking’s Kevin Hancock explains why brokers must take a proactive role in rebuilding perceptions of insurance.\nIn this blog, Ian Lloyd, head of technical product at RAC, discusses why breakdown insurance remains relevant today despite improvements in automotive technology and what brokers need to think about when choosing products for their motor customers.\nIn December, the UK’s PRA set out its priorities for the insurance sector in 2021, whilst the FCA continues to focus on ensuring equitable pricing and treating customers fairly. This blog highlights regulations on the horizon and why nimbler insurers will navigate 2021’s uncertainties more easily.\nM&A activity, providing fair value to customers, pricing transparency and high levels of switching have made customer data management a key challenge for insurers. This blog highlights how ID matching can help insurers build more transparent pricing and a better customer journey.", "pred_label": "__label__POS", "pred_score_pos": 0.9508472084999084} +{"content": "A national protocol agreed between police and legal chiefs to protect the health and safety of criminal defence solicitors during the pandemic has been revised to support the return of in-person attendance at police stations.\nThe protocol was\nintroduced last year and stated that legal advice for suspects should take place whenever possible over telephone and by video link. From May, it no longer applied in cases involving children or vulnerable adults requiring an appropriate adult.\nA\nnew version, which comes into force on Monday, states that advice provided by legal representatives in person will be the default position. Exceptions include the suspect having, or believed to have, Covid, and where there are health and safety concerns in relation to the police custody suites.\nSociety president I. Stephanie Boyce said: 'The protocol was introduced as a temporary emergency measure and we have always made it clear that in-person advice is preferable and should be reverted to as soon as possible. Despite the successful vaccine rollout, Covid-19 hasn’t gone away, and it remains crucial to balance the essential right to have one’s solicitor present in custody, with the need to maintain safety for all.\n‘We believe the new protocol is an important step towards returning to face-to-face legal advice but with safeguards in place to allow for remote hearings where necessary.’\nBoyce said members should contact the Society if the exceptions allowed under the protocol are denied or where they believe the health and safety measures at individual police stations are inadequate.\n‘What happens in the police station, and the careful judgements solicitors are required to make there, affect entire cases - illustrating how critical this often out-of-hours and poorly paid work is,’ Boyce said.\nThe protocol has been agreed by the Crown Prosecution Service, National Police Chiefs’ Council, Law Society, Criminal Law Solicitors Association and London Criminal Courts Solicitors’ Association.", "pred_label": "__label__POS", "pred_score_pos": 0.5443612933158875} +{"content": "Gymnastics is a sport that includes physical exercises requiring balance, strength, flexibility, agility, coordination, and endurance. The movements involved in gymnastics contribute to the development of the arms, legs, shoulders, back, chest, and abdominal muscle groups. Gymnastics evolved from exercises used by the ancient Greeks that included skills for mounting and dismounting a horse, and from circus performance skills. The most common form of competitive gymnastics is artistic gymnastics, which consists of, for women (WAG), the events floor, vault, uneven bars, and beam; and for men (MAG), the events floor, vault, rings, pommel horse, parallel bars, and horizontal bar. The governing body for gymnastics throughout the world is the Fédération Internationale de Gymnastique (FIG). Eight sports are governed by the FIG, which include Gymnastics for All, Men's and Women’s Artistic Gymnastics, Rhythmic Gymnastics, Trampoline (including Double Mini-trampoline), Tumbling, Acrobatic, Aerobic and Parkour. Disciplines not currently recognized by FIG include Wheel gymnastics, Aesthetic group gymnastics, Men's Rhythmic Gymnastics, TeamGym, and Mallakhamba. Participants in gymnastics-related sports can include young children, recreational-level athletes, and competitive athletes at varying levels of skill, including world-class athletes.", "pred_label": "__label__POS", "pred_score_pos": 0.9019730091094971} +{"content": "PREAMBLE\nThe purpose of this document is to provide guidance to applicants submitting proposals for funding consideration under the Tourism Fund stream. Funding approval will be granted for projects in line with the strategic objectives of the fund.\nBACKGROUND\nThe newly launched Operation Vula Fund is a funding scheme initiated by the Department of Economic Development, Tourism and Environmental Affairs (EDTEA) with the aim of ensuring that adequate support is provided for the establishment and promotion of sustainable emerging enterprises which include SMMEs and Cooperatives. Funding support will also be aimed at achieving radical economic transformation, with funding availed to the historically disadvantaged groups within the provincial economy who are able to come up with sustainable and profitable initiatives which create wealth and sustainable jobs.\nThe Tourism Fund will be managed under the Operation Vula Fund within EDTEA, as annual grant funding for the 2019/20 financial year. The funding will be utilised to reduce funding gaps within existing and start-up tourism businesses.", "pred_label": "__label__POS", "pred_score_pos": 0.6434711217880249} +{"content": "Keep construction workplace clean and tidy with our range of basic cleaning products and construction cleaning materials.\nWe offer a range of industrial cleaning supplies for canteens, offices and bathrooms.\nTo remove debris, multi-purpose cleaners with sponges or cloths can provide anti-bacterial or anti-viral benefits. Disinfectants or watered down bleach, however, produce better anti-viral and anti-bacterial results.\nReduce harmful chemicals in a workplace by swapping traditional chemical cleaners with eco cleaning products.", "pred_label": "__label__POS", "pred_score_pos": 0.9007883071899414} +{"content": "The sale of dogs, cats, and rabbits in retail pet stores is one step closer to being banned in New York State. On Tuesday, the New York State Senate passed Bill SB4234, which prohibits the sale of dogs, cats, and rabbits by retail pet shops; instead, authorizing space in the stores to be used for the adoption of animals. The bill has now moved to the Assembly for vote. If passed by the Assembly, the critical bill will then head to the Governor’s desk for his signature to establish it as law. “Today the N.Y. Senate passed my anti-puppy mill bill banning the sale of dogs, cats, and rabbits in retail pet stores,” New York Senator Michael Gianaris, who sponsored the critical bill, said in a post on his Facebook page. He further noted that animals that are sold in pet stores are often sourced from cruel and barbaric mills. Gianaris was compelled to draft the bill after speaking with local pet store owners and researching the violations of their questionable suppliers. He was left “aghast” at the deplorable conditions that these poor innocent animals have to endure. On the Senate floor, Gianaris explained that while the public views the “puppy in the window” as cute, most are unaware of the brutal and awful conditions that animals bred by unscrupulous breeders are subjected to; noting that they are treated as commodities and not sentient beings that will become beloved members of people’s families. “These people are not looking at these animals as lives to be respected, but as a way to make more and more money,” stated Gianaris. California was the first state to enact such legislation, prohibiting dogs, cats, and rabbits to be sold in retail pet stores; instead promoting adoption from local rescue groups and shelters. Maryland followed with legislation that only allows pet shops to adopt out dogs and cats that come from local shelters as well.\nhttps://worldanimalnews.com/breaking-new-york-state-senate-passes-bill-banning-the-sale-of-dogs-cats-bill-now-moves-to-the-assembly-for-vote/", "pred_label": "__label__POS", "pred_score_pos": 0.5622521042823792} +{"content": "抄録\nTwo diphosphines bearing an ethynylene and a 1,2-phenylene linkers between the sterically crowded triarylphosphine moieties have been synthesized by employing Sonogashira and Suzuki-Miyaura couplings as key reactions, respectively. Intramolecular interactions between the two phosphine moieties were studied by UV–Vis spectroscopy and cyclic voltammetry. The UV–Vis spectrum of the ethynylene bridged diphosphine exhibits visible absorption in longer wavelength than that of the 1,2-phenylene bridged derivative reflecting lower LUMO spreading over the diphenylacetylene moiety. On the other hand, the cyclic voltammogram of the 1,2-phenylene bridged diphosphine shows larger difference of the first and the second oxidation potentials reflecting larger positive charge repulsion upon oxidation. The trend observed in the UV–Vis absorptions is similar to that of the structurally related diamines, whereas the voltammograms show the opposite trend, or dependence on the distance between the redox centers, reflecting the limited π-conjugation of the triarylphosphines.\nASJC Scopus subject areas 生化学 創薬 有機化学", "pred_label": "__label__POS", "pred_score_pos": 0.5638075470924377} +{"content": "This artice is free to access.\nMaheshvara (mahe), an RNA helicase that is widely conserved across taxa, regulates Notch signaling and neuronal development in Drosophila. In order to identify novel components regulated by mahe, transcriptome profiling of ectopic mahe was carried out and this revealed striking upregulation of JAK/STAT pathway components like upd1, upd2, upd3, and socs36E. Further, significant downregulation of the pathway components in mahe loss-of-function mutant as well as upon lowering the level of mahe by RNAi, supported and strengthened our transcriptome data. Parallelly, we observed that mahe, induced caspase-dependent apoptosis in photoreceptor neurons, and this phenotype was significantly modulated by JAK/STAT pathway components. RNA immunoprecipitation unveiled the presence of JAK/STAT tyrosine kinase hopscotch (hop) transcripts in the complex immunoprecipitated with Mahe, which ultimately resulted in stabilization and elevation of hop transcripts. Additionally, we also observed the surge in activity of downstream transcription factor Stat92E, which is indicative of activation of the JAK/STAT signaling, and this in turn led to apoptosis via upregulation of hid. Taken together, our data provide a novel regulation of JAK/STAT pathway by RNA helicase Maheshvara, which ultimately promotes apoptosis.\nCITATION STYLE\nMaurya, B., Surabhi, S., Das, R., Pandey, P., Mukherjee, A., & Mutsuddi, M. (2021). Maheshvara regulates JAK/STAT signaling by interacting and stabilizing hopscotch transcripts which leads to apoptosis in Drosophila melanogaster.\nCell Death and Disease, 12(4). https://doi.org/10.1038/s41419-021-03649-0", "pred_label": "__label__POS", "pred_score_pos": 0.7676082849502563} +{"content": "This striking photograph shows the deadly blow humans have inflicted on the Niger Delta.\nParts of the once-thriving ecosystem in Nigeria's oil-rich delta have been transformed into an ecological dead zone because of oil bunkering - the practice of siphoning oil from pipelines.\nOil pirates puncture holes in pipelines, steal the crude oil, and then transport it to be sold on the black market or to be refined.\nBoth the theft and refining process leave behind oil spills that cause severe environmental damage to the delta, turning it into a scorched earth of oil slicks, polluted waters and sparse vegetation.\nThe rusted structures seen here are part of the refining process, while the boats are used to transport the stolen oil to various locations hidden deep in the delta.\nThis shot by photographic artist Edward Burtynsky is part of his new multidisciplinary project, Anthropocene, which explores the idea proposed by some scientists that a geological epoch shaped by human activity has begun.\nIt is the second of a series featuring his unsettling images that will explore the impact of humanity on the planet.\nTOMORROW: Fertiliser producer Uralkali's potash mine in Berezniki, Russia.", "pred_label": "__label__POS", "pred_score_pos": 0.9078319668769836} +{"content": "In September 2021, Cumberland Lodge is hosting a cross-cultural conference of academics and cultural leaders, convened by Lord (Stephen) Green, to explore a paper first circulated by Lord Green in December 2020, on connections and relations between the world's major metaphysical traditions in an increasingly intercultural world.\nIncreased global connectivity necessitates increased cultural interaction, which can be fruitful but also carries risks - and there is evidence that geopolitical tensions are rising as a result. This increased connectivity across diverse cultures creates both the need and the opportunity for mutual understanding, through shared learning and understanding about the deep commonalities in human life experience. These commonalities find expression particularly in the prolonged search, widespread in all of the world’s great living cultures, for answers to fundamental metaphysical questions.\nThere are some striking differences in the ways these questions have been understood and addressed, and these have already been explored in a series of video discussions convened online by Lord Green in 2021. The first face-to-face meetings on this theme take place at Cumberland Lodge in Windsor Great Park on 13-14 September 2021. Background reading for the four main sessions is available below, and conference resources from the conference will be shared here in due course. Contributors are invited to share relevant materials for this project area via the conference leads.\nConference documents\nBackground reading for each of the four conference sessions will be shared here shortly.", "pred_label": "__label__POS", "pred_score_pos": 0.5113122463226318} +{"content": "Dumbarton Oaks\nPieter Schengenga presenteert op symposium in Dumbarton Oaks, hieronder de engelse beschrijving van het programma.\nResilience and adaptability are key elements of viable urbanism. But how have these concepts been understood historically? And how do they shape the design and stewardship of urban landscapes today? The dynamic relationships between cities and their rivers, a landscape of potentially critical adaptability and resilience, is the focus of “River Cities: Historical and Contemporary.” Building on the emergence of urban humanities and urban landscape history, we propose to consider the urban river as a city-making landscape deserving of careful reading and analysis: past, present, and future.\nThe subject of this symposium builds on a new multiyear initiative in Urban Landscape Studies, which Dumbarton Oaks is launching in 2015 with support from the Andrew W. Mellon Foundation. Its principal goal is to create a dialogue between designers and scholars to address the landscape consequences of advancing urbanization. With this task in mind, the 2015 symposium aims to bring together the work of contemporary designers with the historical perspectives of scholars, encouraging practitioners and historians to bridge the gaps between their modes of thinking.", "pred_label": "__label__POS", "pred_score_pos": 0.6021308898925781} +{"content": "As members of the Library profession, we recognize the importance of making known to the general public the ethical principles that guide the work of library staff. Libraries significantly influence or control the selection, organization, preservation, and dissemination of information. In a political system grounded in an informed citizenry, we are members of a profession explicitly committed to intellectual freedom and the freedom of access to information.\nWe provide the highest level of service to library users through appropriate and usefully organized resources; equitable service policies; equitable access; and accurate, unbiased, and courteous responses to all requests. We uphold the principles of intellectual freedom and resist efforts to censor library resources. We protect each library user’s right to privacy and confidentiality with respect to information sought or received and resources consulted, borrowed, acquired or transmitted. We recognize and respect intellectual property rights. We treat co-workers and other colleagues with respect, fairness and good faith, and advocate conditions of employment that safeguard the rights and welfare of all employees of our library. We do not advance private interests at the expense of library users, colleagues, or our library. We distinguish between our personal convictions and professional duties and do not allow our personal beliefs to interfere with fair representation of the aims of our library or the provision of access to its information resources. We strive for excellence in the profession by maintaining and enhancing our own knowledge and skills, by encouraging the professional development of co-workers, and by fostering the aspirations of potential members of the profession.\n—————————————\nPlease refer to the\nManagement Policy set for more information.\nThe Estes Valley Library\nCode of Professional Ethics is adapted from the American Library Association Code of Ethics. It was adopted and approved by the Estes Valley Public Library District Board of Trustees on March 14, 2005, revised December 12, 2011, reviewed on November 16, 2015 and revised April 16, 2018 and August 16, 2021. John Krueger, President Pete Johnson, Secretary", "pred_label": "__label__POS", "pred_score_pos": 0.8489784002304077} +{"content": "The Surprising Time You Might Want To Avoid Coffee (Well, Maybe)\nNot even 100-degree weather or a dangerously bumpy subway ride will stop me from sipping on a scalding cup of coffee. So, when a co-worker of mine speculated that coffee might worsen period cramps, I was a bit dismissive of the idea. It's not that I didn't believe her, it's just that I didn't want to believe her. So, I turned to the experts for a second opinion. Here's what OB/GYNs have to say about consuming caffeine during your menstrual phase.\nIt's important to note: It's not the coffee itself that raises questions here-it's the caffeine. So, while decaf drinkers can proceed as normal, the answer isn't quite as clear-cut for caffeine fiends.\nIf you look to guidelines from the American College of Obstetricians and Gynecologists, avoiding caffeine is recommended to help relieve PMS symptoms, whereas, one 2016 study", "pred_label": "__label__POS", "pred_score_pos": 0.9123255014419556} +{"content": "Central Bank Digital Currencies (CBDCs) can make cross-border payments more efficient as identified by a report prepared by the Bank of International Settlements (BIS). The report also mentioned that the countries now should work together keeping interoperability in mind. This news has also started gaining traction around the world as the countries have started working together to improve cross-border payments.\nThe report is jointly prepared by the BIS Committee on Payments and Market Infrastructures, the BIS Innovation Hub, the International Monetary Fund (IMF), and the World Bank. The report focuses on how CBDCs can facilitate cross-border payments and lead to multilateral coordination that has major potential for global impact.\nJon Cunliffe, chair of the Committee on Payments and Market Infrastructures and deputy governor for the financial stability of the Bank of England released a statement, saying, “Reforming cross-border payments to make them cheaper, faster and more reliable is a priority and the G20 has endorsed a roadmap to address the key challenges. While many of the roadmap’s actions seek to improve the existing cross-border payments ecosystem, CBDCs offer the opportunity to start with a ‘clean slate, It is crucially important that central banks take the cross-border dimension into account, in their work on potential CBDCs and so avoid many of the challenges in today’s legacy technologies and processes.”\nTill now, no major jurisdiction has launched CBDC officially launched a CBDC and a large number of policies and designs remain unresolved. Additionally, most CBDC investigations by the Central Bank focus on domestic issues.", "pred_label": "__label__POS", "pred_score_pos": 0.5586841106414795} +{"content": "Anaerobic Hybrid Digesters are a combination of Upflow Filter Digester (UFF) and Upflow Anaerobic Sludge Blanket (UASB). With over 90% reduction in Biochemical Oxygen Demand (BOD) and over 70% reduction in the Chemical Oxygen Demand (COD) and lesser space requirement in comparison to other available technologies, it is a good treatment option available for the clients who face stringent effluent discharge regulations.\nFurther, as the growth of the fixed film of biomass occurs on the plastic media, the need or requirement to develop and maintain granular sludge reduces by a significant margin. This is a significant advantage that is suggested during feasibility analysis when Anaerobic Hybrid Digesters are compared with other anaerobic reactors which are available in the market.\nMoreover, biogas which is generated from the process can be used to generate electricity. This reduces the fuel demand to generate the plant, or, to reduce the amount of electricity bought from public or private organizations.", "pred_label": "__label__POS", "pred_score_pos": 0.6747123003005981} +{"content": "Computer Science > Computers and Society Title:Including Everyone, Everywhere: Understanding Opportunities and Challenges of Geographic Gender-Inclusion in OSSDownload PDF Abstract: The gender gap is a significant concern facing the software industry as the development becomes more geographically distributed. Widely shared reports indicate that gender differences may be specific to each region. However, how complete can these reports be with little to no research reflective of the Open Source Software (OSS) process and communities software is now commonly developed in? Our study presents a multi-region geographical analysis of gender inclusion on GitHub. This mixed-methods approach includes quantitatively investigating differences in gender inclusion in projects across geographic regions and investigate these trends over time using data from contributions to 21,456 project repositories. We also qualitatively understand the unique experiences of developers contributing to these projects through a survey that is strategically targeted to developers in various regions worldwide. Our findings indicate that gender diversity is low across all parts of the world, with no substantial difference across regions. However, there has been statistically significant improvement in diversity worldwide since 2014, with certain regions such as Africa improving at faster pace. We also find that most motivations and barriers to contributions (e.g., lack of resources to contribute and poor working environment) were shared across regions, however, some insightful differences, such as how to make projects more inclusive, did arise. From these findings, we derive and present implications for tools that can foster inclusion in open source software communities and empower contributions from everyone, everywhere. Bibliographic and Citation Tools Code and Data Associated with this Article Recommenders and Search Tools arXivLabs: experimental projects with community collaborators\narXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website.\nBoth individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them.", "pred_label": "__label__POS", "pred_score_pos": 0.996185302734375} +{"content": "For years, frontline mental health workers have spoken about how Victoria’s mental health system doesn’t deliver for consumers. Consumers deserve a holistic, integrated, responsive service system provided by qualified, skilled, and supported mental health workers.\nDespite spiralling demand, staffing increases have failed to keep pace, leading to ongoing service breakdowns where staff and consumers are exposed to violence. While all Victorians are suffering the consequences of a failing mental health system, older people, Aboriginal and Torres Strait Islanders, and Victorians living in rural and remote locations are the most disadvantaged. These groups require flexible and tailored supports, including models of earlier intervention across all ages.\nThe Victorian Government has acknowledged the need for wholesale improvements to Victoria’s mental health system through its commitment to establish a Royal Commission into Mental Health.\nVictorian mental health service delivery needs substantial reform. Flagrant core structural problems are long-term under-investment and lack of accountability of funding. The chronic under-investment in mental health services has occurred over a lengthy period where a service demand has spiralled, creating a dysfunctional system because of unmanageable workloads. With a 37% increase in new service users recorded last year, we see one mental health-related emergency presentation every 10 minutes in our hospitals.\nThese are the solutions the Royal Commission can deliver to address the chronic issues in mental health.", "pred_label": "__label__POS", "pred_score_pos": 0.8067721128463745} +{"content": "Abstract\nCurrent research is increasingly relying on large data analysis to provide insights into trends and patterns across a variety of organisational and business contexts. Existing methods for large-scale data analysis do not fully capture some of the key challenges with data in large datasets, such as non-response rates or missing data. One method that does address these challenges is the SunCore algorithm for cross-evaluation (ACE). ACE provides a view of the whole dataset in a multidimensional mathematical space by performing consistency and cluster analysis to fill in the gaps, thereby illumining trends and patterns previously invisible within such datasets. This approach to data analysis meaningfully complements classical statistical approaches. We argue that the value of the ACE algorithm lies in turning 'big data' into 'smart data' by predicting gaps in large datasets. We illustrate the use of ACE in connection to a survey on employees' perception of the innovative ability within their company by looking at consistency and cluster analysis.\nOriginal language English Pages (from-to) 24-47 Number of pages 24 Journal International Journal of Transitions and Innovation Systems Volume 6 Issue number 1745-0071 Publication status Published - 2018 Externally published Yes", "pred_label": "__label__POS", "pred_score_pos": 0.5071645975112915} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis issue brief explores Elementary and Secondary School Emergency Relief Funds (ESSER) and how these funds can support summer and afterschool programs. It reviews amount of ESSER funds for each state, what the funds can be used for, and how programs can access these funds through grants and contracts. It also includes examples of how CT, GA, NH, UT, and WV are using the funds.\nThis webinar provided an overview of federal stimulus funding, specifically, the American Rescue Plan and the funding available to state and local education agencies, as well as $1.22 billion specified for summer as well as for afterschool. It also included speakers about the USDA meal program, Community Schools, and the American Camp Association on summer.\nThis webinar explores best practices in providing older youth with supportive and meaningful employment experiences and paid internships. The panel includes representatives from National Youth Employment Coalition, Summer Youth Employment Program from Charlotte, NC, College to Congress, and Community Relations Manager from Bank of America.\nThe National Summer Learning Association has provided more than 40 webinars called the Voices of Summer Webinar Series. The webinars were held between spring 2019 and spring 2021. Presenters include national thought leaders, program providers offering promising practices, and researchers.\nThese webinars feature thought leaders, researchers, journalists, and award-winning program leaders who share practices and research. November 16, 2020 included providers sharing promising practices during the pandemic. November 17 included journalists to explore how the election might shape the landscape and leaders who talked about legislation needed right now.\nThis report from National Summer Learning Association (NSLA) examines data from focus groups and interviews conducted with 21 leaders representing 15 national award-winning summer learning programs in September 2020 and data from a survey of 1,047 afterschool and summer providers conducted in partnership with Afterschool Alliance in July and August 2020.\nThe purpose of this playbook is to provide a long-term and sustainable framework for planning and executing evidence-based practices and partnerships for high-quality summer programs. It has a user-friendly design and includes sections on quality, safety, policies and funding, planning, and partnerships.\nThis webinar features Dr. Gil Noam from Partnerships in Education and Resilience (PEAR) who explores what the field might expect regarding an increase in mental health issues since the pandemic.\nThis virtual press conference brought together leading experts to explore summer solutions emerging in the pandemic. It begins with a review of the findings from the report by the National Academies of Sciences, Engineering, and Medicine on Shaping Summertime Experiences.\nThis issue brief is an interview with researcher Jessica Manta-Myer about an evaluation of the Summer Science Project in 10 elementary school sites in CA. The programs were provided with hands-on curriculum, training, and coaching in STEM. Evaluation showed increased knowledge, skills, and confidence for students, and staff confidence in leading STEM, as well as staff retention.", "pred_label": "__label__POS", "pred_score_pos": 0.8444501757621765} +{"content": "Netherlands Aerospace Centre (NLR) reported (24-Sep-2021) its industry road map for decarbonisation shows the amounts of sustainable aviation fuels (SAF) being produced from biobased feedstocks and available in the Netherlands will only meet a fraction of anticipated fuel demand by 2050. NLR also estimated the supply potential for synthetic kerosene, produced using CO2 that has been recycled or captured from the atmosphere and renewable electricity, is larger and may be sufficient. However, this depends heavily on the amount of excess renewable electricity allocated to the aviation sector. [more – original PR]", "pred_label": "__label__POS", "pred_score_pos": 0.913496196269989} +{"content": "In ancient China, Confucius also employs a version of the Golden Rule (\"Do not impose on others what you yourself do not desire\"; Analects 15.25, Lau trans.; cf. 5.12) However, the next great Confucian, Mencius, offers a subtly and interestingly different view. His focus is rather on \"extending\" one's concern or love or respect from those close to you (or those you can see) to others farther away.\nHere's the key difference, it seems to me: Whereas Golden Rule or empathy accounts start from presumed concern for\noneself first, and then transfer that concern to others (perhaps by an imaginative act), Mencian extension starts from presumed concern for others nearbyand then transfers that concern to others farther away (by noting that those farther away merit similar consideration).\n(For example, Mencius says, \"Among babes in arms there is none that does not know to love its parents. When they grow older, there is none that does not know to respect its elder brother. Treating one's parents as parents is benevolence. Respecting one's elders is righteousness. There is nothing else to do but extend these to the world\" [7A15, Van Norden trans.].)\nWe can, of course, allow for both means of coming emotionally to take others into account in one's ethical reasoning. Both self-concern and familial concern are deep-seated. There's something especially appealing, though, about the Mencian process. It starts less egoistically and closer to the target as it were; and it might be easier logically and emotionally to justify the shift from concern for someone nearby to someone far than to justify the shift from self-concern to other concern.", "pred_label": "__label__POS", "pred_score_pos": 0.7055003046989441} +{"content": "Ductal carcinoma in situ in core biopsies containing invasive breast cancer: correlation with extensive intraductal component and lumpectomy margins.J Surg Oncol. 2005 May 01; 90(2):71-6.JS BACKGROUND AND OBJECTIVES\nThe diagnosis of invasive breast cancer is most commonly made on image-guided core biopsy (CB). The presence of extensive intraductal component (EIC), as identified on subsequent lumpectomy, is associated with an increased risk of positive margins and need for further surgery. CBs demonstrating invasive breast cancer may also contain ductal carcinoma in situ (DCIS), although the significance of this finding is unclear. The objective of this study was to examine the implications of DCIS found in the original CB, specifically related to the risk of EIC and/or positive lumpectomy margins.\nMETHODS\nAll patients at a single academic institution who underwent initial breast conserving surgery for invasive breast cancer diagnosed on image-guided CB between 05/00 and 04/02 were included in the study. A systematic, blinded review of all CB and lumpectomy specimens was performed using standardized criteria for DCIS, EIC, and margins.\nRESULTS\nA total of 95 patients were included in the study, with a mean of 5 (median 5) CB/patient. Of these, 43 (45%) patients had DCIS identified in their CB; in 34 (79%) of these patients, the DCIS was mixed with the invasive cancer. No differences in tumor size or lumpectomy volume were identified between patients with or without DCIS on CB. However, patients with DCIS were noted to be significantly younger. Overall, EIC was identified in 13 (14%) patients; the risk of EIC was significantly higher in patients with DCIS identified in CB than in those with invasive carcinoma alone (30% vs. 0%, respectively; P < 0.0001). Expectedly, the incidence of positive margins on lumpectomy was higher in patients with EIC (38% vs. 16%; P = 0.05). A trend, although not statistically significant, towards positive margins was also noted in patients with DCIS on CB compared to those with invasive carcinoma alone (24% vs. 15%, P = 0.3).\nCONCLUSIONS\nThe identification of DCIS in conjunction with invasive cancer on CB appears important; the absence of DCIS in a CB sample excludes the possibility of eventually identifying EIC. Knowledge of DCIS in CBs with invasive carcinoma may be helpful for surgeons in planning gross resection margins at lumpectomy.\nMeSH Pub Type(s) Language PubMed ID Citation Journal of Surgical Oncology,vol. 90, no. 2, 2005, pp. 71-6. J Surg Oncol. 2005;90(2):71-6. Journal of Surgical Oncology, 90(2), 71-6. J Surg Oncol.2005 May 1;90(2):71-6. PubMed PMID: 15844190.", "pred_label": "__label__POS", "pred_score_pos": 0.6376259326934814} +{"content": "Our initial discussions with you are designed to determine if our philosophy aligns with your personal and business objectives. We will engage in vision-building dialogues with you discussing your plans for the future and showing you a valuable new way of thinking about your financial strategy. We then work with you to articulate a process that will fulfill your future’s potential.\nAfter envisioning where you want to go, we need to define where you are today. We will gather your financial information to create a clear picture of both your current and ideal financial position. This information provides a valuable instrument as we map a course toward your vision of prosperity.\nUsing the information you share, we focus on your objectives and assess your current situation. A blueprint of your current wealth status will be created to analyze your financial strategy, identify potential inefficiencies, and project likely outcomes of your current courses of action. This is a time for clarity, exploration, and growth as you begin to realize the wealth of possibilities that exist for the future you are creating.\nHere is where your future gains momentum. You begin to see the power that is available to you using the WestPac Wealth Partners holistic planning process as your guide. The innovative strategies we implement on your portfolio aim to be measurable and designed to help give you superior results instead of average product performance.\nAfter our strategies have been integrated into your financial pathway, we want to hear what you have to say about the WestPac Wealth Partners experience. Since we work exclusively through personal introductions from our clients, we aim to enhance our process every time. This conversation also sets the stage for our communications for the upcoming year before your annual review. During this time, we like to allow you to share this vital process with those closest to you. We’re dedicated to your future and everyone in it.", "pred_label": "__label__POS", "pred_score_pos": 0.9790509343147278} +{"content": "Wild American Ginseng Stock #725-8 (50 capsules)\nToday, American ginseng is listed under the Convention of International Trade in Endangered Species (CITES) to preserve what remains of native populations. This plant is rarely seen in the wild due to over-harvesting. Wild American ginseng is now being cultivated in Wisconsin, China, and France.\nThe Chinese consider American ginseng an entirely different plant with different medicinal properties than Panax ginseng (Korean ginseng). American ginseng is a white ginseng with cooling, anti-inflammatory properties. It is considered more balancing, or more yin, and is often recommended for individuals with “overheated” conditions due to stress, excessive caffeine intake, or over-stimulation. American ginseng is used to break fevers such as scarlet fever and stimulate fluid production, especially saliva, in dehydrated individuals.\nThe Chinese also consider American ginseng to be beneficial for the lungs and use it to treat dry coughs due to lung chi deficiencies. Chinese medicine prescribes American ginseng as a yin tonic for treating blood loss, coughs, fatigue, fever, hot flashes, irritability, night sweats, smoking, thirst, weakness, and wheezing, and for weakened individuals, to improve the body’s tolerance to various types of stress. American ginseng is also recommended for relieving bleeding due to internal heat such as blood in the urine and stools, nose bleeds, and excess uterine bleeding.\nWomen entering menopause may find American ginseng helpful for the unpleasant side effects often associated with this period in life. American ginseng can cool hot flashes and night sweats and help relieve irritability. However, Dr. Letha Hadady, author of Asian Health Secrets, warns that American ginseng can promote water retention in the digestive tract, especially in those with slow metabolism.\nOlder Asian women are said to drink a tea made from American ginseng every day to maintain their beauty, tone and refine their skin, strengthen fragile capillaries, and reduce dryness and wrinkles.\nUnfortunately, at present, there is a lack of solid scientific research on verified American ginseng studies, as most research conducted to date used Panax ginseng or did not specify which species were used.\nAmerican ginseng should not be used during colds or flu as it is known to stimulate fluids and increase phlegm. Women should avoid using American ginseng during pregnancy.", "pred_label": "__label__POS", "pred_score_pos": 0.8205978870391846} +{"content": "Poly(ionic liquid)s (PILs) with an intrinsically conducting pyrrole polymer (ICP) backbone were synthesized and utilized as novel dispersants of carbon nanotubes (CNTs) in various polar and nonpolar solvents. This is due to their highly tunable nature, in which the anions can be easily exchanged to form PILs of varying polarity but with the same polycation. These CNT dispersions were exceedingly stable over many months, and with the addition of hexane, Pickering emulsions with the PIL-stabilized CNTs at the droplet interfaces were formed. Depending on the hydrophobicity of the PIL, hexane-in-water and hexane-in-acetonitrile emulsions were formed, the latter marking the first non-aqueous stabilized-CNT emulsions and corresponding CNT-in-acetonitrile dispersion, further advancing the processability of CNTs. The PIL-stabilized CNT Pickering emulsion droplets generated hollow conductive particles by subsequent drying of the emulsions. With the emulsion templating, the hollow shells can be used as a payload carrier, depending on the solubility of the payload in the droplet phase of the emulsion. This was demonstrated with silicon nanoparticles, which have limited solubility in aqueous environments, but great scientific interest due to their potential electrochemical applications. Overall, this work explored a new class of efficient PIL-ICP hybrid stabilizers with tunable hydrophobicity, offering extended stability of carbon nanotube dispersions with novel applications in hollow particle formation via Pickering emulsion templating and in placing payloads into the shells.\nContributors\nCreated\n2015-12", "pred_label": "__label__POS", "pred_score_pos": 0.8686770796775818} +{"content": "CMS Proposes New and Significantly Enhanced Enrollment Requirements\nThis webinar will provide an in depth review of the proposed rule released by CMS on March 1, 2016, entitled, “Medicare, Medicaid, and Children’s Health Insurance Programs; Program Integrity Enhancements to the Provider Enrollment Process” that, if finalized, would have a significant impact on providers and suppliers operating in the Medicare, Medicaid and CHIP programs. Consistent with CMS’s recent history of utilizing the enrollment rules to combat fraud, waste and abuse through early identification efforts tangential to the enrollment process, this Proposed Rule seeks to expand CMS’s arsenal by adding yet another set of enrollment and revalidation reporting requirements, as well as significant expansions to CMS’s ability to deny and revoke the billing privileges of providers and suppliers.\nIf enacted, these proposed rules will, in part:\nCreate new obligations on providers and suppliers to monitor and disclose certain present and past “affiliations” with other providers or suppliers who/that underwent certain “disclosable events” Create new bases for a CMS denial or revocation of a provider’s or supplier’s enrollment Increase the length of re-enrollment bars in the event of a revocation Increase the length of re-application bars in the event of a denial Implement changes to CMS’s enrollment moratoria authority Implement changes to the process for reactivating a deactivated supplier’s billing privileges", "pred_label": "__label__POS", "pred_score_pos": 0.5012286901473999} +{"content": "Like me, the hon. Member was, and presumably still is, a councillor. Between 2010, when I was a councillor in Camden, and the start of the pandemic, there were £16 billion-worth of cuts to local government, and the Environment Agency saw its Government funding slashed by nearly two thirds. The direct result of that underfunding is that councils have struggled to deal with plastic waste effectively, and there has not been enough monitoring and enforcement of the rules. As a fellow Member of Parliament and a current councillor, does the hon. Member agree that reducing plastic waste relies on local councils and bodies such as the Environment Agency having the resources that they need to do so?", "pred_label": "__label__POS", "pred_score_pos": 0.6760621070861816} +{"content": "How can we\nmake films more sustainable?\nHello! If you're here, it's because sustainability and film are things that matter to you.\nThe environmental impact of the creative industries can be overwhelming, but it doesn't have to be that way! Together we can apply approaches and methods decreasing that footprint.\nWhat is a green consultant?\nA green consultant advises production companies at all stages of a film's production - from script via shooting to editing, or even its release - always with a focus on sustainability. As it is about using resources more efficiently and consciously, this often translates into financial savings. A win for the planet and a win for you.", "pred_label": "__label__POS", "pred_score_pos": 0.958480954170227} +{"content": "The insurance marketplace commonly goes through its “hard” and “soft” cycles where premium fluctuations have little relation to individual loss experience. These swings can be avoided by joining with other like-minded, successful companies to create your own group captive insurance company, making your costs more predictable and stable. In this way, you can lower your costs and earn investment income — both benefits you won’t receive from a traditional insurance company.", "pred_label": "__label__POS", "pred_score_pos": 0.6929154396057129} +{"content": "Abstract\nThe boredom and alienation produced by capitalist societies and countervailing forces of attraction and excitement are at the heart of the subcultural account of crime. The underground hacker subculture is no exception, commonly represented as based around exciting, technically skilled practices and high-profile deviance. However, the illicit economy associated with these practices has become industrialized, developing shared infrastructures that facilitate the sale of illicit services rather than skilled technical work. We explore how this shift in the nature of work has shaped the culture and experiences of this subculture. Developing a novel concept—the ‘illicit infrastructure’—and drawing on an extensive analysis of empirical data from interviews and novel data sources such as forums and chat channels, we argue that as they industrialize, deviant subcultures can begin to replicate the division of labour, cultural tensions and conditions of alienation present in mainstream capitalist economies.", "pred_label": "__label__POS", "pred_score_pos": 0.9991679787635803} +{"content": "Abstract\nBackground and study aims Capsule endoscopy(CE) is a well-established investigation for iron deficiency anemia (IDA) and melena, usually following negative upper and lower endoscopy. We aimed to study the effect of earlier CE in the investigative pathway for inpatients with IDA or melena at a large tertiary referral centre. Patients and methods We analyzed inpatients undergoing CE for IDA or melena from 2005 to 2017, without signs/symptoms suggesting lower gastrointestinal tract pathology. Patients underwent CE following negative upper and lower gastrointestinal endoscopy (Group 1), or negative upper gastrointestinal endoscopy (UGIE) only (Group 2). Results One hundred and seventy inpatients underwent CE for IDA (n = 44) and melena (n = 126). In Group 1, 46/95 (48.4%) patients had small bowel (SB) findings. CE found 16/95 (16.8 %) gastric and 12/95 (12.6 %) colon findings. Three of 12 patients with colon findings required repeat colonoscopy. One hundred and three colon investigations were carried out for 95 admissions. In Group 2, 33/75 (44.0%) patients had SB findings. There were 12/75 (16.0 %) gastric and 11/75 (14.7 %) colon findings. In patients with positive CE, significant colonic findings led to colonoscopy in 10 of 39 patients (diagnostic yield 6/10). Thirty-six patients had negative CE; 15 underwent colonoscopy (diagnostic yield 9/15). The remaining 21 of 36 patients with no further colonoscopy did not develop adverse outcomes related to colonic pathology. Twenty-six colon investigations were carried out in 75 admissions. Patients in Group 2 had shorter mean times from admission to CE (5.08 ± 3.80 vs. 6.38 ± 3.80 days; P = 0.02) and hospital stays (10.5 ± 9.58 vs. 12.5 ± 11.4 days; P = 0.04) compared to Group 1. Conclusion Earlier use of CE in inpatients with melena or IDA, no signs of lower gastrointestinal pathology and negative UGIE resulted in shortened hospital stays, significant DY from both small bowel and upper gastrointestinal tract, and two-thirds less unnecessary colon investigations without affecting clinical outcomes.", "pred_label": "__label__POS", "pred_score_pos": 0.7163444757461548} +{"content": "Debates on capitalism get muddled by blind spots about essential institutions, particularly\neffective governments and legal systems that enable corporations to exist in their current form and markets to succeed at scale. Across regimes, incentives to maximize profits and power play key roles in determining outcomes, and all institutions are vulnerable to distortions from imbalances in control, information, and expertise. The key problems with capitalism today boil down to failed governance and confusions that obscure the issues and prevent beneficial changes.\nIn recent decades, the forces of “free-market capitalism” have undermined and overwhelmed\ndemocratic institutions, leading to intertwined crises in both capitalism and democracy. Deception and the manipulation of beliefs often distort both markets and political systems. The financial system illustrates starkly how key institutions have failed society and how flawed narratives enable recklessness and bad rules to persist.\nFixing capitalism must start with seeing the challenges for what they are. The devil is then in the\ndetails of improving transparency, norms, rules, and civic engagement so as to prevent the abuse of power and to create more trustworthy and less corruptible versions of capitalism.", "pred_label": "__label__POS", "pred_score_pos": 0.5654106736183167} +{"content": "From someone dropping off dinner at the doorstep of a neighbour with COVID-19 to an octogenarian in India giving up his oxygen bed for a middle-aged patient, instances of people giving to those in need without expectations has made headlines during the COVID-19 pandemic.\nPeople are often in direct competition for shared resources, so biologically, it would make sense that there would be an expectation that giving must be reciprocal. Yet even in situations characterized by intense competition, giving and sharing can take precedence over winning, whether it’s Olympians giving up their medal positions to help peers in need or small businesses banding together to help fellow entrepreneurs hit by the pandemic.\nWhy do people give without expecting anything in return? This question continues to baffle sociologists because, theoretically, unilateral giving and receiving within a community cannot be sustained as the desire to receive without any obligation to give back can give rise to more takers than givers.\nAs organizational theorists, we were interested in the dynamics surrounding unilateral giving when the combined motives of co-operation and competition co-exist. Our research team published our findings in the\nAdministrative Science Quarterly. We examined how acts of giving emerge and are sustained in a Silicon Valley business accelerator.\nEarly stage entrepreneurs increasingly gravitate towards start-up accelerators, which provide them access to investors, clients and the experiences of fellow entrepreneurs.\nA typical accelerator brings together entrepreneurs who are unlikely to have known each other prior to entering the program. Besides providing participating entrepreneurs access to potential investors and clients, a key goal of accelerators is to create a supportive community of entrepreneurs.\nIn a typical start-up accelerator, entrepreneurs are expected to give to their fellow entrepreneurs without expectations, but those seeking help can find themselves competing for resources, including mentorship and funding.\nCreates a cycle of giving\nIn our eight-month study of an accelerator in Silicon Valley, we followed three start-up camps. In the beginning, entrepreneurs across all camps actively sought help from fellow entrepreneurs. But the responses to these early requests differed across camps, setting in motion positive or negative dynamics.\nWe discovered that a single act of giving to a fellow entrepreneur in need spurs a cycle of gratitude and giving in the network. On the other hand, a single act of refusal to help triggers a cycle of shaming and avoidance. But what motivates these early acts of giving?\nAt the heart of these dynamics are social interactions at events like formal onboarding events, weekly progress meetings, informal dinners, parties or outdoor activities. The accelerator program was structured so that one of the camps regularly engaged in weekly progress meetings, while others did not.\nThe accelerator’s weekly progress meetings, which we label “tournament rituals,” focused on entrepreneurs’ shows of strength as they discussed progress made on their products or services. In other camps, informal weekend get-togethers, which we label “bonding rituals,” organically emerged thanks to formal onboarding events that focused on building familiarity among entrepreneurs.\nIn these bonding rituals, entrepreneurs let their guards down and opened up about challenges they faced as entrepreneurs. This helped participants realize their common experiences as entrepreneurs and the need to help their peers.\nThose who participated in these bonding rituals were not only comfortable asking other entrepreneurs for help, but also received help from their peers who gave without expecting anything in return. These early acts of giving generated a sense of gratitude among receivers who willingly paid it forward. This giving-gratitude cycle eventually resulted in a thriving community of giving and a dense network populated by positive relationships.\nShows of strength don’t lead to giving\nOn the other hand, those show-of-strength or tournament rituals generated an expectation among entrepreneurs to be strategic in exchanging resources with others in the accelerator program. Accordingly, when participants strategically approached knowledgeable entrepreneurs in their camp for help, they were rebuffed because their peers saw no value in lending a helping hand.\nThese early failed exchanges became shaming rituals — for example, entrepreneurs who felt undervalued and rejected by fellow entrepreneurs in their camp avoided interacting with them to steer clear of further negative experiences. This shaming-avoidance cycle resulted in a rapid dissolution of ties and what remained, in the end, was a sparsely connected network.\nIn short, organic bonding rituals helped competitors identify with each other, triggering and sustaining early acts of giving. But tournament rituals only encouraged entrepreneurs to further their own interests, which eventually gave rise to more takers than givers.\nWe believe our research offers valuable insights into human interactions. Beyond start-up accelerators, our research applies to other organizational contexts where both competitive and co-operative motives exist. For instance, our research offers critical lessons for organizations looking to build a more collaborative culture.\nAlthough employees are expected to co-operate, they also compete with each other for promotions. Formal meetings are a regular feature in organizations, but they can foster collaboration by ensuring they focus on the camaraderie among members rather than celebrating their individual wins.\nAvoiding shows of strength in formal meetings can also encourage employees to engage in bonding rituals outside the organization, which our study shows are essential for building bonds within the group.\nAmid the pandemic era, which has left more people feeling lonely and distanced from their community — not willingly but reluctantly — our research underscores the importance of bonding rituals for building healthy communities of giving.\nThis article is republished from The Conversation, a nonprofit news site dedicated to sharing ideas from academic experts. It was written by: Rekha Krishnan, Simon Fraser University and Rajiv Krishnan Kozhikode, Simon Fraser University. Read more: Rekha Krishnan receives funding from SSHRC - Social Sciences and Humanities Research Council of Canada. Rajiv Krishnan Kozhikode receives funding from The Social Sciences and Humanities Research Council of Canada.", "pred_label": "__label__POS", "pred_score_pos": 0.509200930595398} +{"content": "ObjectivesRandoms and scatter corrections are essential and critically important for improving the contrast and quantitative accuracy in PET imaging. Iterative reconstruction algorithms have also been demonstrated to improve image quality. In this work, we describe a practical method of incorporating any existing randoms and scatter corrections into the system matrix of iterative PET reconstructions without increasing the matrix size.\nMethodsWe compared the images reconstructed with our Practical Randoms and Scatter System Model (PRSSM) method to those reconstructed with the conventional Ordinary Poisson (OP) approach using contrast and resolution phantoms. The PRSSM method estimates the trues fraction within the prompts for each line-of-response using the variance reduced randoms, the single scatter simulation, and the acquired prompts. The trues fraction is then incorporated into the weighting component of the system matrix (i.e. the diagonal elements) similar to the attenuation correction weighting. The images were reconstructed using 3D-OSEM.\nResultsFrom the contrast and resolution vs noise and iteration, we have observed that the PRSSM method iterates towards (~5%) higher contrast values and converges faster as compared to the conventional OP method. Similar results were observed from the resolution measurements with the PRSSM method reaching a slightly higher resolution and noise at the same iteration. The reconstruction task was also observed to be up to 10% faster for the PRSSM method as there is no need to process through the randoms and scatter sinograms in the forward projection step for every iteration as compared to the OP method and the computation of the trues fraction is sufficiently fast.\nConclusionsThe preliminary results demonstrated that the PRSSM method can stop at an earlier iteration and achieve similar/higher contrast and resolution as compared to the conventional OP method with a faster reconstruction time. The PRSSM method needs to be further evaluated and optimized for various counting statistics", "pred_label": "__label__POS", "pred_score_pos": 0.8145231008529663} +{"content": "Oceanview Belief floats $351 million in jumbo mortgages\nAs the US economy gradually enters pandemic lockdown mode, several aspects of home loan borrowers are also returning to pre-COVID-19 levels, including self-employed borrower levels in Oceanview Mortgage Trust 2021-3 or OCMT 2021-3, the expected to issue $ 351 million in debt securities.\nSelf-employed borrowers made up 18.7% of the borrowers in the pool that secured the deal. For 2020 and 2021, the average combined percentage of self-employed borrowers was 19.5%, according to the Kroll Bond rating agency.\nThe self-employed had slightly weaker credit fundamentals, according to KBRA, as they were more affected by the pandemic due to business closings. For example, the original FICO for self-employed was 773 while full-time employees had a FICO of 779. The original self-employed combined loan-to-value ratio (CLTV) for the underlying loans was 61.6%. , compared to 69.3% for full-time employees.\nIn total pool and weighted average, OCMT 2021-3 borrowers had significant, documented liquidity reserves of $ 553,483 for high quality jumbo loans. Compared to recent transactions, borrowers have also been shown to have high residual income.\nAll of the loans in the pool were qualified mortgages, which KBRA considers credit positive.\nConsistent with the fact that jumbo mortgages are often made at high home prices, the pool is heavily invested in California assets. This state accounted for 22.6% of the pool balance while Virginia, Texas, Florida and Maryland account for 10.3%, 9.8%, 7.2% and 4.7%, respectively.\nAnother aspect of jumbo loans is that the customers are often high net worth borrowers. While the underwriting terms of such loans are conservative, they pose a risk to RMBS pools of jumbo loans as a single loan can constitute a significant portion of the pool balance.\nFrom a different perspective, the top five core-based statistical areas (CBSA) were Washington, DC (11%); Los Angeles (6.5%); San Francisco (5.4%), Dallas, Texas (4.0%) and Philadelphia (3.4%).", "pred_label": "__label__POS", "pred_score_pos": 0.7398214340209961} +{"content": "A young trainee nurse who was hospitalised with three blot clots after getting the AstraZeneca vaccine has encouraged Australian's to register for it despite the 'rare' side effects.\nEllie Peacock, who works in a hospital in Queensland, is backing the vaccine despite having a bad experience with it after receiving the first dose on March 31.\nIt is understood that she got her jab on week before the government announced people under 50 would no longer be receiving the AstraZeneca jab due to blood clot concerns.\nEllie suffered from severe headaches and chest pains, and was diagnosed with pneumonia before her doctors discovered that she had blood clots in her lungs.\nAccording to the Therapeutic Goods Administration (TGA), the condition which is known as thrombosis with thrombocytopenia syndrome is \"very rare\".\nNow, the nursing student is required to get blood tests weekly, go in for a CT scan every month and take blood thinning medication for six months.\nHowever, the bad experience has not wavered her support for the jab.\n\"I think people should still follow the TGA guidelines,\" she told A Current Affair.\n\"I'm not an anti-vaxxer. I've never missed a vaccine in my life. I've never had side effects to any other vaccine. This is the first one I've had a reaction to.\"\nEllie confirmed in her interview that she had received a call from the TGA confirming that the blood clots were indeed linked to the vaccine.\n\"When the information, you know, from the database comes out, yes, her case will be counted amongst them,\" a TGA representative said.\nAs a trainee nurse, she works on a casual team in Brisbane that is regularly exposed to potential Covid-19 positive patients, making it imperative for her to receive the vaccine.\nOn April 18, more than two weeks after getting the jab, Peacock presented to the Royal Brisbane Women's Hospital emergency room with throbbing and tightness in her calf, which she says were \"signs of clotting\".\nShe had an ultrasound which failed to identify any blood clots and was sent home, with the pain in her calf eventually subsiding, the Courier Mail reports.\nShortly after, Peacock started suffering from regular, painful headaches, which she ignore until May 7 when she began experiencing a severe pain near her collar bone when inhaling.\nTwo days later, she went back to the hospital after experiencing severe muscle pain in her back and ribs, only to receive a chest x-ray and be told she has pneumonia.\nThe trainee nurse was sent home once again.\nAt 2am on May 11 Peacock was rushed to the hospital's emergency department for the third time after having extreme breathing difficulties.\n\"I was sent home within six hours without further testing done and was told that it's normal pain with pneumonia and that I need to put up with the pain until the medications start working,\" she told the Courier Mail.\nA couple of days later she visited her GP who discovered her oxygen levels had dropped to 90 per cent, resulting in her once again presenting to the hospital.\nThis time Peacock insisted on more tests, which is when the true nature of her illness was discovered.\n\"After persisting for further testing, they finally found three blood clots in one lung,\" the 18-year-old wrote on Instagram.\nShe said the doctor believes when they did the initial ultrasound on her calf in April the clot had either already moved to her pelvis or was too small to be detected.\n\"This experience has been terrifying and overwhelming but I'm on the mend. Now to focus on my health for the next six months,\" she said.\nPeacock claims because her blood clotting didn't fit the usual timeline for similar incidents she was forced to convince doctors of what was happening to her.\n\"So please always listen to your body because no one knows it as well as yourself,\" she wrote on Facebook.\nAs of Thursday last week, there have been a total of 18 thrombosis with thrombocytopenia syndrome (TTS) cases likely linked to the AstraZeneca vaccine in Australia.\nSo far about 1.8 million doses of the vaccine have been administered across the country.\nLast week there was a surge in blood clot cases following the AstraZeneca vaccine.\nThree cases on May 13 were confirmed as TTS, while four were deemed \"probable\".\nThe three confirmed cases included a 75-year-old man from Victoria, a 75-year-old man from Western Australia and a 59-year-old Queensland man who was diagnosed in Victoria.\n\"Of these, only the Victorian man remains in hospital, but is responding to treatment and is in a stable condition,\" a TGA said.\n\"The other two patients are not currently in hospital and are thought to be well.\n\"Four other newly reported cases are considered to be probable TTS. This includes three men from Victoria aged 65, 70 and 81 years, and a 70-year-old man from NSW.\"\nThe TGA maintains that reporting rates of blood clotting in Australia are \"consistent with what is being seen internationally\".\nThough it did note a \"higher proportion of less severe cases may be being reported in Australia\".\n\"This may be due to high levels of awareness in the community and among the medical profession around TTS along with less strain on the healthcare system around Covid infections with much lower infection rates than internationally,\" the TGA said.", "pred_label": "__label__POS", "pred_score_pos": 0.6098543405532837} +{"content": "Earth re-entering spacecrafts traveling at high Mach number generate a strong shock layer ahead of the blunt body with a high temperature above 60,000 K. These extreme Mach number and temperature flows are sufficiently energetic to initiate gas ionization and thermo-chemical ablation processes. The nonequilibrium energy distribution of atoms and molecules in air causes significant radiative energy that can add or remove energy from the flowfield. To perform accurate and efficient analyses of chemically reacting flowfield - radiation interactions in hypersonic nonequilibrium flows the direct simulation Monte Carlo (DSMC) and photon Monte Carlo (PMC) methods were used to simulate flowfield - radiation coupling of Stardust reentry flows at near continuum regime altitudes. We perform closely coupled DSMC - PMC simulations using a ray tracing schemes of photon bundles that travel through the same DSMC computational cell and with small statistical error. The radiative heat source calculated by the PMC method is then transfered to flowfieid which influenced by the add or removal of radiative energy as calculated by the PMC. For these near continuum flow regimes, the radiation was found to influence the flowfield. The high radiative energy leads to a decrease in both heavy particle translational and internal temperature in the shock layer and a decrease in the convective heat flux to the Stardust body. The DSMC - PMC coupled simulations are performed until both the flow and radiation fields are converged.", "pred_label": "__label__POS", "pred_score_pos": 0.9652395844459534} +{"content": "Homelessness in communities across Alabama is on the rise with no clear end in sight. According to the U.S. Department of Housing and Urban Development (HUD), you can find an estimated 3,400 people sleeping on the streets on any given day.\nHere at Kilgro & Associates Insurance Agency, our priority is to protect what matters to us most, beginning here with our community. As advocates for the safety and wellness of our most vulnerable neighbors, we are thrilled to announce we will be working alongside Tennessee Valley Outreach to support and bring hope to the hopeless.\nThis non-profit organization exists to combat homelessness and provide the gift of opportunity to individuals in need. Their team of dedicated staff and experienced volunteers work one-on-one with homeless clients to create a personalized strategy that identifies and tackles specific challenges while also offering training and support for long-term success. By providing these services, individuals are guided back to self-sufficiency and independently living quickly.\nTennessee Valley Outreach would love to meet the needs of every individual experiencing homelessness, but they can’t do it alone. Recommend your friends, family, and co-workers to receive an insurance quote from us, and we’ll donate $20 for every person! They only need to receive a quote – there is no obligation to purchase. All funds raised during our campaign will go to Tennessee Valley Outreach to support and create a positive change in our community!\nCLICK HERE CLICK HERE", "pred_label": "__label__POS", "pred_score_pos": 0.8965567350387573} +{"content": "A detailed inventory - compiled by JRC scientists - of 800 knowledge sources relevant to the Replacement, Reduction and Refinement (Three Rs) of animal procedures used for scientific purposes.\nDB-ALM dataset is a publicly accessible collection of alternative method summaries and protocols. DB-ALM focuses primarily on methods submitted to EURL ECVAM for validation, and those identified in ad hoc reviews of the literature and end-users in specific application areas between 2000 and 2019.\nIn a detailed analysis of the scientific literature, over 21,000 abstracts (11,636 non-cancer and 9,421 cancer) were scanned for relevant non-animal models of respiratory disease (e.g. asthma, COPD).\nA guide to searching for information relating to alternative methods and 3Rs. It provides search principles and procedures, suggested search terms and user guidance together with an inventory of relevant information resources.", "pred_label": "__label__POS", "pred_score_pos": 0.983813464641571} +{"content": "Researchers are determined to manufacture stretchable biomedical devices that interface directly with organs such as the skin, heart and brain. Electronic devices, however, are usually made from hard materials that are incompatible with soft tissue. Choon Chiang Foo from the A*STAR Institute of High Performance Computing, Singapore, and researchers at Harvard University, United States, are aiming to solve this dilemma with squishy, see-through gels that can act as integral components of stretchable devices thanks to an innovative ionic conduction mechanism.\nFoo and co-workers made their discovery while investigating a promising 'artificial muscle' technology known as dielectric elastomers. These devices sandwich an insulating rubber polymer between two conductive electrodes, typically made from micro-cracked metals or carbon grease. Applying a voltage to the electrodes builds up pressure which causes the inner polymer to expand. Most electrode materials, however, begin to lose conductivity when subjected to high strains.\nThe researchers chose to replace the electrodes in dielectric elastomers with soft hydrogels. Hydrogels are transparent and biocompatible materials, typically used in contact lenses, which encapsulate salty ions and water inside a polymeric sheath. Replacing the electrodes requires overcoming two well-known limitations of ionic conductors: their slow speeds relative to electron conductors and a tendency to undergo destructive electrochemical reactions at high voltages.\nThe team's setup addresses these problems by placing a thin insulating rubber sheet between two hydrogel layers. Electric signals sent to the hydrogel through tiny electrodes leads to rapid buildup of oppositely charged ions on each side of the rubber sheet causing the sandwiched device to thin and expand over the entire area. Furthermore, the rubber layer has a remarkably low capacitance, which causes a large voltage drop across the rubber and shields the hydrogel from electrochemical reactions, even at kilovolt ranges.\nTo demonstrate the high-frequency operation of their stretchable ionic material, the researchers produced the world's first gel-based transparent loudspeaker (see image). This device, which could be placed over a smartphone or flat-screen television screen, resonated thousands of times per second over the entire audible range.\nFoo, whose theoretical contributions proved critical to understanding the novel behavior of these stretchy gels, believes this work may lead to a fundamental shift in how engineers conceive electronic devices.\n\"Because existing conductors struggle to meet the demands of stretchable applications, device designers may begin to ask if they can replace electronic conductors with ionic conductors,\"he explains. \"The device may lose some performance but may gain other attributes, such as stretchiness, transparency and biocompatibility.\" Source and top image: A*STAR Research Top image: a transparent ionic gel, pictured here in front of a laptop computer, can transform electric signals into sound across the entire audible range.\nFor more attend the forthcoming event:", "pred_label": "__label__POS", "pred_score_pos": 0.5043074488639832} +{"content": "What are the challenges to care coordination? In this video, Sean Boynes, DMD, MS, vice president of health improvement at CareQuest Institute, explains how coordination can be daunting because it requires bridging silos and exposing a portion of your operation to someone else. Providers may hesitate to be open and honest about the weaknesses in their practices. But there are opportunities, too. True care coordination will require a significant cultural change and recognizing the deep connections between oral disease and overall systemic health.\nYou may also be interested in:\nMORE Care, an initiative of CareQuest Institute that aims to integrate oral health competencies and capabilities into primary care offices while building patient-centered referral networks with local dental providers using health information technology. A Three Domain Framework to Innovating Oral Health Care, a white paper that outlines a new model in dentistry that will be more cost-effective, efficient, and equitable. Medical-Dental Integration web page, a collection of resources that explore the growing connections between oral health and overall health.", "pred_label": "__label__POS", "pred_score_pos": 0.9283874034881592} +{"content": "The hard outer layer of your teeth, the enamel is incredibly strong and durable. However, it has some limitations. Some common causes of chipped teeth like falling down and impacting the mouth, chewing on ice, popcorn kernels on non-food items can chip your teeth. In addition, teeth weakened from decay are also susceptible to chipping. If you have a chipped tooth, you can visit a dental clinic offering emergency dental services to receive prompt treatment.\nChipped teeth are painful and need attention from a dental professional. Your teeth can sustain damages in several ways, and the damage can be minor or significant depending on the condition of your teeth and the type of injury. Unless you have a minor chip, do not think you can fix it without help from a dentist. However, you can address the pain you experience and protect your tooth beside the inside of your mouth to prevent further injuries.\nIt’s an excellent idea to call emergency dentistry soon after realizing you have chipped a tooth in your mouth. Meanwhile, there are some self-care measures you can take. Rinse your mouth with warm water right away to clean it is recommended by the American Dental Association. If the chipped tooth is bleeding, use a piece of sterile gauze over the bleeding area. Apply some pressure to stop the bleeding and use ice packs over your cheeks to control swelling.\nYou can flush the inside of your mouth with warm water and apply a cold compress to your cheeks every few minutes to keep the swelling down. In addition, over-the-counter pain relievers and anti-inflammatories can help you manage the discomfort from the chipped tooth. However, please do not exceed the recommended dosage and stay away from any painkillers that also act as blood thinners that might increase bleeding instead of preventing it.\nChipped teeth are not all similar, and you might have different types of chips. When you get to the emergency dental clinic near you, the dental professional will examine your teeth thoroughly. The dentist keeps you informed which type of chips affects you and the treatment best suited for your condition.\nIf you have chipped your molar of the lower jaw because of their pointy cusps grinding powerfully against the grooves of the upper molars, these injuries are the most common and may leave you with a broken cusp requiring extensive treatments. You must fix chipped tooth if you have a fractured cusp in the molars because the area becomes a breeding ground for bacteria and food particles to remain trapped and create additional damage to your tooth. In such cases, the dentist recommends treating the broken cusp with a tooth restoration like a dental crown.\nHowever, if you have very fine lines or craze lines as they are also known, you might not require treatment. Instead, the dentist may polish the tooth to eliminate any rough spots to ensure the chip doesn’t cause any discomfort in your mouth.\nA minor chipped front tooth is restored by dentists using tooth-colored filling material to replace lost enamel. You can also inquire with the dentist about getting dental bonding to fix the chipped tooth and restore it to appear like your natural teeth. However, do not try to fix the tooth yourself because you might create additional damage in your mouth.\nMany people assume a chipped tooth is a minor problem that does not cause any significant issues. However, every chip or crack other than craze lines occurring on the enamel needs an evaluation from your dentist because trying to determine the intensity of the damage is pretty challenging for yourself. There are no effective home therapies to prevent additional injuries to your teeth, and the sharp edges of the chipped tooth can cut through your soft tissues to cause more pain and infection, needing expensive treatment. In some cases, an untreated chip can require a root canal, tooth loss, or other complications because of an infection.\nYou can use home repair kits available with drugstore and online retailers to cover the chipped tooth while you wait for an appointment to see your dentist. However, do not delay the treatment for too long because the bacteria in your mouth will undoubtedly get to the chip and, through it to create more infections in your mouth.", "pred_label": "__label__POS", "pred_score_pos": 0.5286107659339905} +{"content": "A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.The file type is\napplication/pdf.\nABSTRACTNew global history studies have provided theoretical models related to different paths of economic growth and consumer behaviour between East Asia (mainly China and Japan) and Europe during the period of the first industrialisation. However, more research challenging the Eurocentric views of the origins of globalisation is needed. In this article, I examine the exchanges of Chinese silks and porcelains and European wines and liquors for American silver through the Swedish Grill Company.doi:10.1017/s0212610919000235 fatcat:iypqfexpljconodrh6i2sa5gym", "pred_label": "__label__POS", "pred_score_pos": 0.5276211500167847} +{"content": "A balanced scorecard for measuring the impact of industry–university collaboration 2011 Production planning & control (Print)\nThe Balanced Scorecard (BSC) can be considered as a strategic measurement tool. Since its first publication by Norton and Kaplan in the early 1990's, many companies have applied it to measure four key aspects of their organisations' performance: Financial, Customer, Internal Business Process, Learning and Growth. Although it is widely used in the business arena, this original BSC was not developed to assess the impact of collaborative research projects under an open innovation strategy, where doi:10.1080/09537287.2010.536626 fatcat:4dbpir4mjfa2dhnlgba4yu6bou\nmore » ... n strategy, where the outputs of research and development (R&D) developed by collaborative projects undertaken by industry and universities should be measured in a different way. Therefore, this paper will propose a Scorecard to measure the outcomes of collaborative research. It is important to recall that this scorecard has been developed during a collaborative research project by CEMEX Research Group AG (Switzerland) and Cranfield University (UK). During such project, a survey was developed to carry out eleven face-to-face interviews in a sample of ten companies in UK, where it was confirmed that a collaborative balanced scorecard (CBSC) is a very useful tool to measure, track and improve the impact of conducting collaborative projects with universities. It should also be noted that this paper is an extended version of the one presented at the PRO-VE'09.", "pred_label": "__label__POS", "pred_score_pos": 0.6820168495178223} +{"content": "Green Lithium is an innovative development company with plans to construct, commission and operate a large-scale lithium refinery in the UK, and provide high-purity lithium hydroxide to UK and European markets\nOVERVIEW:\nThe company will harness industry-leading process technology enabling clean, low-carbon processing of high volumes of lithium ore\nThere is currently no large-scale refining capability in Europe despite a significant market opportunity. Working with key strategic partners to address the need to improve the European battery-metal supply chain, Green Lithium will support the ‘net-zero’ ambitions of society to transition to the future green economy.\nGreen Lithium’s refinery will be a cornerstone UK green-infrastructure asset, enabling UK-based cathode, battery cell and EV manufacture, ushering in an era of decarbonisation and green jobs, and supporting long-term economic prosperity.\nHISTORY:\nThe project started when founders Richard Taylor and Guy Hatcher identified a critical gap in the future UK and European battery supply chain\nThis led them to undertake extensive work mapping hard-rock lithium resources and, in the process, gain deep understanding of the lithium mineral ecosystem. Four years later, Green Lithium has secured over £2m in funding through private investment and government grants, established a detailed programme of delivery, assembled a core project delivery team comprising 60+ in-house and third-party team members, and formed commercial partnerships with key suppliers and offtakers.\nLATEST NEWS:\nJuly 2021\nJune 2021\nSeptember 2021\nGreen Lithium secures grant funding from UK Government automotive grant funder the Automotive Transformation Fundlondonstockexchange.com", "pred_label": "__label__POS", "pred_score_pos": 0.9152240753173828} +{"content": "You are here Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons. Abstract\nLittle is known about the organizational and functional connectivity of the corticospinal (CS) circuits that are essential for voluntary movement. Here, we map the connectivity between CS neurons in the forelimb motor and sensory cortices and various spinal interneurons, demonstrating that distinct CS-interneuron circuits control specific aspects of skilled movements. CS fibers originating in the mouse motor cortex directly synapse onto premotor interneurons, including those expressing Chx10. Lesions of the motor cortex or silencing of spinal Chx10+ interneurons produces deficits in skilled reaching. In contrast, CS neurons in the sensory cortex do not synapse directly onto premotor interneurons, and they preferentially connect to Vglut3+ spinal interneurons. Lesions to the sensory cortex or inhibition of Vglut3+ interneurons cause deficits in food pellet release movements in goal-oriented tasks. These findings reveal that CS neurons in the motor and sensory cortices differentially control skilled movements through distinct CS-spinal interneuron circuits.", "pred_label": "__label__POS", "pred_score_pos": 0.9881076812744141} +{"content": "Valuation of Barrier Options in a Black-Scholes Setup with Jump Risk\nPosted: 29 Mar 2001\nAbstract\nThis paper discusses the pitfalls in the pricing of barrier options using approximations of the underlying continuous processes via discrete lattice models. To prevent from numerical deficiencies, the space axis is discretized first, and not the time axis. In a Black-Scholes setup, models with improved convergence properties are constructed: a trinomial model and a randomized trinomial model where price changes occur at the jump times of a Poisson process. These lattice models are sufficiently general to handle options with multiple barriers: the numerical difficulties are resolved and extrapolation yields even more accurate results. In a last step, we extend the Black-Scholes setup and incorporate unpredictable discontinuous price movements. The randomized trinomial model can easily be extended to this case, inheriting its superior convergence properties.\nKeywords: barrier option, binomial model, lattice-approach, option valuation JEL Classification: C63, G12, G13", "pred_label": "__label__POS", "pred_score_pos": 0.7696201205253601} +{"content": "What are critical success factors in business and how to identify them?\nThey are the few key areas where things must go right for the business to flourish.\nThere are four main types of CSFs. Each of the CSFs that you establish in your organization will likely fall into, and have been defined by, one of these groups.\nIndustry factors\nResult from the specific characteristics of your industry. These are the things that you must do to remain competitive within your sector. For example, a tech start-up might identify innovation as a CSF.\nEnvironmental factors\nResult from macro-environmental influences on your organization: the business climate, the economy, your competitors, and technological advancements, for example. A PEST Analysis can help you to understand environmental factors better.\nStrategic factors\nResult from the specific competitive strategy that your organization follows. This could include the way your organization chooses to position and market itself, and whether it's a high-volume, low-cost producer, or a low-volume, high-cost one.\nTemporal factors\nResult from the organization's internal changes and growth and are usually short-lived. Specific barriers, challenges, directions, and influences will determine these CSFs. For example, a rapidly expanding business might have a CSF of increasing its international sales.\nSix Steps to Identify and Develop Your CSFs\nTo identify and develop CSFs for your organization, follow these six steps\ni. Establish your organization's mission and strategic goals\n.\nii. For each strategic goal, ask yourself, \"Success in what area of business or project activity is essential to achieve this goal?\" The answers to the question are your potential (or \"candidate\") CSFs.\niii. Evaluate your list of candidate CSFs to identify the ones that are truly essential for achieving your goals – these are your Critical Success Factors. As you identify and evaluate candidate CSFs, you may uncover some new strategic objectives, or refine existing ones. So, you may need to redefine your goals and CSFs as you go along.\niv. Work out how you will monitor and measure each of your CSFs.\nv. Clearly communicate your CSFs to those responsible for delivering them and to rest of the business.\nvi. Continually monitor and reassess your CSFs to make sure that you stay on track toward your goals. Although CSFs can be less tangible than measurable targets or KPIs, monitor each one as specifically as possible.\nAlthough there's no absolute rule, it's a good idea to limit the number of CSFs to five or fewer. This helps to ensure that each CSF has maximum impact and gives clear direction on priorities to other elements of your business.", "pred_label": "__label__POS", "pred_score_pos": 0.5400247573852539} +{"content": "Beautyrest Hybrid Mattress Review Beautyrest Hybrid\nCombining positive aspects of both innerspring and memory foam mattresses, the Beautyrest Hybrid mattress offers a balanced sleep surface at a reasonable price point.\nBeautyrest currently produces three other models: the Beautyrest Black, the Harmony Lux Carbon, and the Harmony Lux Diamond. However, the Hybrid is the company’s only model to include Beautyrest’s proprietary ContourFit Design. This feature allows the mattress to stretch and conform to the sleeper’s body type and movements.\nThe Hybrid consists of a support core made from pocketed coils, a 4-inch comfort system consisting of gel-infused memory foam and polyfoam, and a quilted stretch fabric cover. Each layer is designed to promote a cool, breathable sleep surface. Both the cover and comfort layers feature the company’s InfiniCool Plus temperature regulation system, while the support core encourages airflow throughout the mattress.\nBeautyrest Mattresses At-A-Glance\nBeautyrest Hybrid Beautyrest Black Firmness Medium (5) Medium Soft (4), Medium Firm (6) Material Type Hybrid Hybrid Height 13.5\" 13\", 15\" Price (queen) $1,299 $2,699 Scroll L - R for more details Beautyrest Hybrid Mattress Review: Our Verdict Choose The Beautyrest Hybrid if… You share your bed with a partner You sleep on your side most or some of the time You weigh less than 130 pounds You’re seeking a trusted brand with a history of producing quality products Keep Shopping if… You weigh more than 230 pounds You tend to sleep hot You prefer a firmer mattress How Much Is the Beautyrest Hybrid Mattress?\nThe Beautyrest Hybrid is a mid-priced luxury mattress that boasts a 100-night sleep trial and a reputation for quality dating back decades. Beautyrest has long been a trusted name on the market and their beds are seen in hotels worldwide.\nSizes Dimensions Weight Price Twin 40\" x 76\" 56 lbs. $1199 Twin XL 40\"x 81\" 59 lbs. $1229 Full 55\" x 76\" 80 lbs. $1279 Queen 61\" x 81\" 99 lbs. $1299 King 78\" x 81\" 130 lbs. $1699 California King 73\" x 85\" 127 lbs. $1699 Scroll L - R for more details How Does the Beautyrest Hybrid Mattress Feel?\nThe Hybrid falls squarely in the middle of the firmness scale, offering a balanced sleep surface that is neither overly firm nor soft enough for most individuals to sink too far into. Most customer reviews of the Beautyrest Hybrid praised the mattress for being supportive without approaching an uncomfortable level of firmness.\nWhile its pocketed coil support core targets key areas like the spine and lower back, the Beautyrest Hybrid’s foam comfort layers offer enough contouring to reduce pain and pressure where many individuals feel it most. Three inches of cooling, gel-infused memory foam cradle pressure points, while another inch of polyfoam prevents sleepers from sinking into the support core. Side sleepers and those under 130 pounds often find the mattress particularly comfortable, while the memory foam layers may offer too much sink and contouring for some other sleepers.\nWhat Is the Beautyrest Hybrid Made Of?\nLike other hybrids, the Beautyrest Hybrid combines a coil-based support core with memory foam comfort layers to deliver the best of both all-foam and innerspring mattresses with fewer of the drawbacks. At 13.5 inches tall, the mattress has a relatively high profile and features three layers, which we’ll explore in depth below.\nCover Material\nDesigned to draw away body heat, the Beautyrest Hybrid’s cover is made from cooling fabric that features the company’s proprietary InfiniCool Plus technology. The cover stretches over time, conforming to the sleeper’s individual movement patterns and body shape.\nComfort Layers\nThe Beautyrest also uses InfiniCool Plus technology in all three of its comfort layers for better temperature regulation. In total, the comfort layer consists of three inches of cooling, gel-infused memory foam to provide body-conforming contouring with minimal sagging. The gel infusion helps to draw excess heat away from the sleeper’s body so it can dissipate through the mattress.\nAnother 1-inch layer of polyfoam acts as a buffer to help keep the sleeper from sinking into the support core. The mattress’s perimeter is reinforced with Beautyrest’s BeautyEdge material and construction.\nSupport Core\nThe model’s support core consists of a strong base of pocketed coils, which isolate motion and offer targeted support at the hips and shoulders. The coils also encourage airflow throughout the mattress, leading to a cooler sleep surface.\nWhat Type of Sleeper Is the Beautyrest Hybrid Mattress Best for?\nSleeping position and body weight both affect mattress performance. The Simmons Beautyrest Hybrid offers a combination of pressure relief and contouring that appeals to side and combination sleepers. Let’s see how the Beautyrest Hybrid mattress affects each type of sleeper.\nSide Sleepers\nSide sleepers often suffer from pressure buildup at the shoulders and hips, which may ultimately lead to back pain. The Beautyrest Hybrid’s comfort layer seeks to relieve pain and pressure with three inches of gel-infused memory foam, while the support core targets key problem areas. Side sleepers will also appreciate the mattress’s medium firmness level.\nCombination Sleepers\nThe Hybrid stands out from other Beautyrest models for its proprietary ContourFit Design. The mattress stretches and conforms to the sleeper’s movements over time, creating a customized sleep surface that aligns with each individual’s unique nighttime patterns.\nBack Sleepers\nBack sleepers tend to require firmer mattresses with more lumbar support and a medium amount of contouring. Overly soft sleep surfaces may cause back sleepers, especially heavier individuals, to sink into the mattress. Despite the Beautyrest Hybrid’s balanced surface, back sleepers who weigh more than 230 pounds will likely sink in too far to feel comfortable.\nStomach Sleepers\nGenerally, stomach sleepers need more firmness and support from their mattress than back or side sleepers. Stomach sleepers who weigh less than 130 pounds report an excellent balance of body-contouring and support from the Beautyrest Hybrid, resulting in good pressure relief and minimal sagging. Those who weigh 130 pounds or more sank somewhat deeply into the mattress and did not feel as comfortable as lighter stomach sleepers did.\nHow Does Body Weight Impact the Beautyrest Hybrid Mattress's Performance?\nLike sleeping position, body weight affects mattress performance, and some models are better suited to certain body types than others. While most Beautyrest Hybrid mattress reviews were positive, weight played a strong role in customers’ experiences.\nAs a whole, individuals under 130 pounds were satisfied with the Beautyrest Hybrid, regardless of their preferred sleeping position. Customers in this weight range often benefit from softer sleep surfaces, which cushion pressure points and provide gentle support. With a medium firmness level of 5, the model offers more contouring than many other hybrids on the market, thanks to its 3 inches of gel memory foam.\nSleepers over 130 pounds were generally less pleased with the Beautyrest Hybrid mattress. Back and side sleepers weighing 130-230 pounds appreciated the model’s firmness level. However, heavier stomach sleepers tend to benefit from firmer mattresses, which prevent them from sinking too far into the surface and causing pressure to build. Stomach and back sleepers over 230 pounds generally found the Beautyrest Hybrid’s gel comfort layers to be too soft and contouring for their needs.\nIs the Beautyrest Hybrid Mattress Good for Couples?\nHybrids enjoy a positive reputation among couples for providing ease of movement and strong edge support, and the Beautyrest Hybrid is no exception. The pocketed coil support core offers the right amount of bounce with less noise, while the BeautyEdge reinforcement system expands the total sleep surface area and prevents sleepers from rolling off the bed’s edge.\nThe model stands out among its fellow hybrids for providing above-average motion isolation, making it ideal for light sleepers and couples with different sleep habits. While coil-based support and motion isolation are often somewhat mutually exclusive, numerous customers remarked on the Beautyrest Hybrid’s ability to dampen their partner’s movements.\nBeautyrest's Trial, Warranty, and Shipping Policies Availability\nThe Beautyrest Hybrid mattress is available online at the brand’s website and on Amazon. Beautyrest products are also available at the brand’s brick-and-mortar locations around the country and at a variety of mattress retailers nationwide.\nShipping\nBeautyrest ships to any state in the contiguous U.S. through XPO Logistics. All customers who purchase a mattress through the Beautyrest website receive complimentary White Glove delivery and setup. XPO Logistics contacts customers to schedule a delivery date and time. Most orders arrive within 7-15 business days of purchase.\nCustomers who purchase a mattress from another retailer should contact their closest Beautyrest dealer to confirm their order and arrange a delivery time. Shipping and delivery conditions vary by retailer.\nAdditional Services\nIndividuals who purchase a mattress through the Beautyrest website qualify for free White Glove delivery. After scheduling a delivery date and time, an XPO Logistics representative will arrive at the customer’s house to set up their new mattress and remove the old one.\nSleep Trial\nBeautyrest offers a 100-night sleep trial for mattresses bought directly from their website. Customers who are dissatisfied with their purchase may return their mattress and receive a full refund if they do so within those 100 days. Those who wish to initiate a return or exchange after the sleep trial is over should contact Beautyrest customer service.\nWarranty\nBeautyrest’s 10-year limited warranty pertains to manufacturing defects only. To qualify for coverage, mattresses must be used with a suitable foundation as defined on the manufacturer’s website, as well as a protector pad. Pairing the mattress with an inadequate foundation will void the warranty.\nPurchasers should hold on to their original bill of sale and keep the mattress tag intact in case they wish to file a claim.", "pred_label": "__label__POS", "pred_score_pos": 0.5080857276916504} +{"content": "Creating the Perfect Sleep Environment for Your Child\nFact-Checked\nIf it feels like your child is on a daily mission to worm their way out of bedtime, you're not alone. Studies suggest that between 15% and 25% (1) of children have trouble sleeping, and many parents are at their wit's end to know why their tot won't stay in bed.\nThere are many factors that could be affecting your child's sleep, but one of the easiest ones to address is their bedroom environment. Just like adults, children sleep best when their bedroom is cool, dark, and quiet (2). If you're struggling with how to get the kids to sleep, consider these options for creating the perfect child sleep environment.\nA Tidy Bedroom\nTeaching your child to associate bed with relaxation at an early age helps pave the way for them to be a good sleeper. As part of the bedtime routine, encourage them to tidy up their room and clear away objects that take the focus away from sleeping, such as toys or homework. If you can, try keeping screens and playtime out of the bedroom altogether, to reinforce the idea that bed is for sleeping (3).\nIf you're wondering how to get your toddler to sleep in their own bed, it's all right to leave them a comfort object such as a teddy bear or security blanket. This can reduce your child's separation anxiety (4) and help them learn to fall asleep without your help. Avoid leaving a bottle with your baby overnight, as this can lead to tooth decay.\nBlackout Curtains\nBright lights from electronic screens (5) and even household lighting (6) can delay the onset of the sleep hormone, melatonin, making it harder to fall asleep. Blackout curtains in the baby or toddler room are an affordable and easy option for keeping out external light. They may be especially convenient for daytime naps, early bedtimes, or bedrooms that let in excessive street light.\nNightlight\nThe darker the sleep environment, the better. However, a nightlight in your toddler's bedroom might give a much-needed sense of security to kids who are scared of the dark. Plus, children who keep a nightlight on won't have to turn on the overhead lights during those nighttime bathroom breaks.\nUsing a nightlight instead of a lamp or overhead light keeps light levels low, reducing stimulation and helping them get back to sleep faster. For best results, keep nightlights on the dimmest setting.\nLowering the Thermostat for Sleep\nKeeping the bedroom temperature on the cooler side helps naturally prepare the body for sleep. The optimal bedroom temperature for sleeping is between 66 and 70 degrees (7), beyond which your child can regulate their own temperature by kicking the blankets on or off.\nFor babies who are too young to control the blankets, it's even more important to keep the room temperature within a comfortable range and dress them in a onesie or sleep sack as appropriate. Avoid over-bundling them, as this can also increase the risk of Sudden Infant Death Syndrome (SIDS) (8).\nWhite Noise\nAmbient noise from outside (9) or inside the house (10) is a common disruptor of sleep quality. Unfortunately, for many children, it's difficult to achieve a totally silent bedroom at night, especially if other family members are still awake. In these cases, a white noise machine can help mask outside sounds. When choosing white noise for toddlers, opt for a steady, low-key sound such as waves lapping or a steady heartbeat, and keep the volume at a level that's safe for your child's hearing.\nSoothing Scents\nFor stubborn sleepers, try harnessing the power of aromatherapy with calming scents such as lavender (11), which is said to help promote relaxation. Keep them away from secondhand smoke (12), which has been known to cause sleep problems in children. If you smoke, try to limit your children's exposure and keep their bedrooms a tobacco-free zone.\nComfortable Mattress, Pillows, and Bedding\nChildren generally sleep better when they have their own bed (13), as opposed to sharing with a parent or sibling. Investing in a child-friendly (14) mattress, pillows, and bedding can help send your tot off to dreamland and wake up the next morning feeling refreshed and ready to go.\nBed-sharing, letting your baby sleep on the couch or car seat, and leaving soft items in the crib can put your baby at risk for Sudden Infant Death Syndrome (SIDS) (15). Always follow age-appropriate guidelines when choosing a mattress and bedding for your child.\nWith just a few tweaks to your child's bedroom, you can vastly improve their sleep setup and set them up for better slumber at home and at daycare. Healthy sleep in children has been linked to better academic performance and a reduced likelihood of developing mood or health problems. Establish good sleep habits (16) and a consistent bedtime routine now, and your child will thank you for it in the future.\nReferences + 16 Sources 1. Accessed on February 25, 2021.https://www.healthychildren.org/English/healthy-living/sleep/Pages/Melatonin-and-Childrens-Sleep.aspx 2. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/19675858/ 3. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/11903859/ 4. Accessed on February 25, 2021.https://www.healthychildren.org/English/healthy-living/sleep/Pages/Healthy-Sleep-Habits-How-Many-Hours-Does-Your-Child-Need.aspx 5. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/25560435/ 6. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/24918238/ 7. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/31105512/ 8. Accessed on February 25, 2021.https://www.nih.gov/news-events/news-releases/nih-alerts-caregivers-increase-sids-risk-during-cold-weather 9. Accessed on February 25, 2021.https://www.sciencedirect.com/science/article/abs/pii/S0272494406000375 10. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/28369539/ 11. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/23573142/ 12. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/23819057/ 13. Accessed on February 25, 2021.https://www.sleepmedres.org/journal/view.php?doi=10.17241/smr.2014.5.1.29 14. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/16335483/ 15. Accessed on February 25, 2021.https://www.nichd.nih.gov/sites/default/files/2020-12/STSEnvironmentAIAN1PagerFinal.pdf#search=sleep-environment 16. Accessed on February 25, 2021.https://pubmed.ncbi.nlm.nih.gov/24634628/ Related Reading:\nCreating a comfy, cozy sleep spot for your newborn is important, but so is putting your baby to sleep carefully. Certain types of bedding can raise the risk of Sudden…\nBabies are asleep for more than half of their first year of life. This time spent sleeping allows an infant's brain and nervous system to develop, preparing them for the years to come. We cover how much sleep your baby needs to promote healthy growth, why sleep is so crucial for infants and toddlers, and answers to the most frequently asked questions about infant sleep habits.\nParents of babies are often sleep-deprived due to their baby's night awakenings. Learn when your baby should sleep through the night and how to help them.", "pred_label": "__label__POS", "pred_score_pos": 0.6516246795654297} +{"content": "Are you a homeowner? Have you secured adequate insurance for your home building and properties? Home insurance is a necessity, which explains why financial lenders require borrowers to have the coverage to access mortgages. Here are the different types of home insurance policies that every homeowner ought to have.\nBuildings Insurance\nThe buildings insurance cover is the foremost homeowner's insurance policy. Essentially, the policy provides coverage for the structure of your house. In this case, the policy covers any permanent fixture on your home, including the roof, walls, and built-in appliances. In addition, building insurance extends to other structures within your residences, such as the garage, sheds, perimeter wall, and gate. Typically, this form of insurance covers incidences and accidents such as fire and vandalism. In the event of such perils, the insurer meets the cost of repairing and rebuilding the dwelling.\nContent Insurance\nA content insurance cover is a type of home insurance policy that protects the items in your home. Such contents include furniture, electronics, home appliances, carpets, and clothing. In most cases, such belongings are expensive, leading to a significant financial setback in the event of a loss. Broadly, one may lose valuable items through perils like flooding, fire, and theft. In such an incident, the insurance company would pay the value of contents based on your policy. In addition, a policyholder may add accidental damage to the contents insurance policy. Notably, this additional policy covers any unintentional damages to your property, such as a broken TV or stained carpet.\nPersonal Liability Insurance\nThe personal liability policy protects from lawsuits resulting from injuries and damages by third parties within your home premises. For instance, a visitor may have a fall accident on your stairs, or your child may damage a neighbor's property. In such situations, you may assume legal responsibility for the injuries and damages. The insurance company would meet the medical bills, liability damages, and legal expenses with a personal liability insurance cover. Thus, personal liability insurance offers financial protection to you and your family. However, the policy excludes any intentional injuries and property damages.\nOptional Home Insurance Coverage\nHomeowners have the option of including separate policies to the home insurance coverage for adequate protection. For instance, homeowners can protect their homes and belongings from flood-related damages through a flood insurance policy. Likewise, they can get earthquake insurance cover if they live in an area prone to earthquakes. In both cases, the policies have their deductibles. Other home insurance policies include high-net-worth home insurance for high-value buildings and items like jewelry and fine art.\nDo your need to insurer your home and contents? Contact a reputable insurance agent to assess your home insurance needs for adequate coverage.", "pred_label": "__label__POS", "pred_score_pos": 0.7104803323745728} +{"content": "[ad_1]\nFriday, U.S. Senator Roy Blunt (Mo.), a member of the Senate Appropriations Committee, announced that several Missouri priories were included in the FY2022 Agriculture and Energy and Water Development funding bills. The bills were approved by the Appropriations Committee by a vote of 25 to 5.\nThe following are some (but not all) of the things included in the bills.\nAgricultural Research: The bill provides $3.6 billion to support agricultural research conducted by the Agricultural Research Service (ARS) and the National Institute of Food and Agriculture (NIFA). This investment will support research, education, and extension activities at the University of Missouri, Missouri State University, Northwest Missouri State University, Lincoln University, and the U.S. Department of Agriculture’s ARS facility in Columbia.\nAgriculture and Food Research Initiative: The bill includes $445 million for the Agriculture and Food Research Initiative, a $10 million increase over FY2021.\nLivestock Genetic Research: The bill includes an additional $3 million for ARS to conduct livestock genetic research.\nFarm Service Agency (FSA): The legislation includes nearly $1.2 billion for various farm, conservation, and emergency loan programs that Missouri farmers and ranchers rely upon, an increase of $35.4 million above the FY2021 enacted level. The bill also prohibits the closure of FSA county offices.\n[ad_2]\nOriginally Appeared Here", "pred_label": "__label__POS", "pred_score_pos": 0.8717032074928284} +{"content": "Commercial Lithium Production and Mining of LithiumGet Price\nAug 27, 2019 · For decades, commercial lithium production relied on mineral ore sources such as spodumene, petalite, and lepidolite. However, extracting lithium from these sources is significantly more costly than extracting the metal from lithium-containing brines. In fact, the cost of extracting lithium from hard rock is estimated to be double that of ...", "pred_label": "__label__POS", "pred_score_pos": 0.9026015996932983} +{"content": "As times continue to evolve working remotely or within our homes has quickly become the new norm. Therefore the importance of creating a space that gives you the clarity and calm you require for your working day cannot denied.\nHowever, creating the perfect balance between both function and form can often be the hardest to achieve. Whilst the space’s functional requirements are crucial to the productivity of the space, the importance of creating a beautiful design driven space the reflects your own style is also of equal importance.\n“When you enjoy what you do, you will never work another day in your life…”\nAnthony Spon-Smith, Co-owner & Creative Director.", "pred_label": "__label__POS", "pred_score_pos": 0.9790006875991821} +{"content": "Ontario Declares Second Provincial Emergency to Address COVID-19 Crisis and Save Lives\nEffective Thursday, January 14, 2021at 12:01 a.m., the government is issuing a stay-at-home order requiring everyone to remain at home with exceptions for permitted purposes or activities, such as going to the grocery store or pharmacy, accessing health care services, for exercise or for work where the work cannot be done remotely. This order and other new and existing public health restrictions are aimed at limiting people's mobility and reducing the number of daily contacts with those outside an immediate household. In addition to limiting outings for these purposes, all businesses must ensure that any employee who can work from home, does work from home.\nIn response to the alarming and exceptional circumstances at hand, and to further interrupt the deadly trend of transmission in Ontario communities, hospitals, and long-term care homes, the following additional public health measures will take effect January 13, 2021 at 12:01 a.m.:\nOutdoor organized public gatherings and social gatherings are further restricted to a limit of five people with limited exceptions. This is consistent with the rules during the lockdown during the first wave of COVID-19 in spring 2020 and will allow individuals and families to enjoy time outdoors safely. Individuals are required to wear a mask or face covering in the indoor areas of businesses or organizations that are open. Wearing a mask or face covering is now recommended outdoors when you can't physically distance more than two metres. All non-essential retail stores, including hardware stores, alcohol retailers, and those offering curbside pickup or delivery, must open no earlier than 7 a.m. and close no later than 8 p.m. The restricted hours of operation do not apply to stores that primarily sell food, pharmacies, gas stations, convenience stores, and restaurants for takeout or delivery. Non-essential construction is further restricted, including below-grade construction, exempting survey. New Enforcement Measures\nThe province will provide authority to all provincial offences officers, including the Ontario Provincial Police, local police forces, bylaw officers, and provincial workplace inspectors to issue tickets to individuals who do not comply with the stay-at-home-order, or those not wearing a mask or face covering indoors in places open to the public, subject to limited exceptions, as well as retail operators and companies who do not enforce requirements under orders under the\nReopening Ontario (A Flexible Response to COVID-19) Act (ROA) or EMPCA. Those who decide not to abide by orders will be subject to a set fine and/or prosecution under both the ROA and EMCPA as applicable.", "pred_label": "__label__POS", "pred_score_pos": 0.9265711307525635} +{"content": "Wait, Don’t Quit! 4 “If you faint in the day of adversity, your strength is small.” Proverbs 24:10\nBehind every successful dream, goal, and mission is a person who has persevered through hardship. They persevered through adversity, pain, and suffering to achieve their goal and accomplish it. Likewise, when we persevere in our faith, we can achieve great things. We can overcome obstacles, setbacks, and failures if we persevere in faith. To patiently wait for God’s appointed time is what God asks of us.\nInpatient and fear cannot cure our problem overnight; therefore, we must not be afraid of what lies ahead because some traces of failure or rejection that are not real will always come knocking at the door or mind when we least expect it. I believe that this is true in life, especially for those that have the opportunity to succeed. But we must never let the fear of the unknown stop us from pursuing our goals and dreams.\nHebrews 12:3 says, “Consider Jesus who endured such hostility from sinners so that you will not grow weary and lose heart.”\nWe must not allow ourselves to be discouraged by discouragement. Instead, we must continue to pursue our dreams and aspirations even when they seem impossible. Jesus didn’t give us a reason to quit. He didn’t come up with an excuse for us to quit life’s challenges. Instead, He endured the trials and tribulations of life for us to enjoy and learn from the experience. Have you learned something from him?\nJesus is faithful and steadfast in his word. He never gives up on us. He never quits forgiving sinner’s sins, restoring the lost, healing the sick, giving a new life to enjoy abundance life to the fullest, and the joy of living God’s purpose despite everything he faced in the world. Therefore, you, too, don’t have an excuse to quit life’s challenges. James 1:2-3 says,\n“Count it all joy, brethren when you meet trials of various kinds because the testing of your faith produces endurance.”\nPrayer:\n1. Dear Lord, I pray that you give me wisdom and strength to do good deeds. 2. Numbers 6:26- Oh Lord, lift your countenance towards me and give me peace in Jesus’ name.", "pred_label": "__label__POS", "pred_score_pos": 0.5856004357337952} +{"content": "PLEASE USE IN-TEXT CITATION Assignment: Group Wiki: Strategic Goals and Potential Challenges\nOrganizational goals that are clearly written and communicated to stakeholders can have many positive effects. For example, organizational goals can help establish priorities, improve decision making, and build teamwork. However, organizations sometimes experience challenges and trends that impact their goals. As a current or future leader and manager of an organization, it is important to consider how you might overcome these potential challenges. In this Group Wiki, you create organizational goals, explore challenges that might impact them, and consider ways to overcome these challenges.\nBy Day 5 To complete:\nIn the Group Wiki, write a summary to address the following with your Final Project in mind:\nExplain 2–3 short-term goals (1–4 years) for your organization. Explain challenges that might impact these goals. Include how the organization might overcome these challenges. Explain 2–3 long-term goals (15–20 years) for your organization. Identify long-term trends (i.e., social, political, demographic, economic, ecological, technological, etc.) that might impact these goals. Explain why it is important to define short-term and long-term goals. Identify and share resources that you might use to help you define your organizational goals.\nDo you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount! Use Discount Code “Newclient” for a 15% Discount!\nNB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.\nThe post Week-7-Assignment appeared first on Custom Nursing Help.", "pred_label": "__label__POS", "pred_score_pos": 0.5615562200546265} +{"content": "Report Summary The Finance Minister, Ms Nirmala Sitharaman tabled the Economic Survey 2020-21 on January 29, 2021. Key highlights of the Survey include: In March 2020, COVID-19 was declared a pandemic by the World Health Organisation, and a nationwide lockdown was imposed in India to contain the spread of the virus. The survey noted that early use of intense lockdowns delayed the time taken to reach the peak and reduced the magnitude of the peak. This led to a low mortality rate and also allowed for a sharp (V-shaped) recovery in economic activities. State of the economy The survey estimates nominal GDP growth of 15.4% and real GDP growth of 11% in 2021-22. In 2020-21, GDP declined by 23.9% in the first quarter and by 7.5% in the second quarter. Overall, GDP is expected to decline by 7.7% in 2020-21 as compared to the growth of 4.2% in 2019-20. Gross Domestic Product (GDP): The Consumer Price Index (CPI) based inflation was 6.6% in 2020-21 (April-December). The inflation mainly due to food inflation which increased from 6.7% in 2019-20 to 9.1% in 2020-21 (April-December). Inflation: In the first half of 2020-21, the current account surplus was 3.1% of GDP. The survey expects current account surplus to be at least 2% of the GDP by end of 2020-21. If achieved, this will break a 17-year trend of current account deficits. The surplus is due to reduction in merchandise imports and lower expense on travel services, which led to higher decline in current payments (30.8%) as compared to the decline in current receipts (15.1%). Current account surplus: As of November 2020, the fiscal deficit was 135.1% of budget estimate. In comparison, between April to November 2019, fiscal deficit was 114.8% of the budget estimate. The survey noted that the country was fiscally strained due to the disruptions caused by the COVID-19 pandemic. Fiscal deficit: Agriculture and allied activities In 2020-21, the growth rate of agriculture is estimated to be 3.4%. While the contribution of the sector to Gross Value Added (GVA) declined from 18.3% to 17.8% between 2014-15 and 2019-20, it is estimated to increase to 19.9% in 2020-21. This is because the agricultural sector faced fewer disruptions on account of the COVID-19 pandemic as compared to non-agricultural sectors. Under National Food Security Act, 2013, the central government provides rice and wheat at subsidised rates (called central issue price (CIP)). The difference between the CIP and the market price gives quantum of food subsidy. While the CIP of wheat and rice has not been revised since the introduction of the Act, the economic cost of wheat increased from Rs 1,908.32 per quintal in 2013-14 to Rs 2,683.84 in 2020-21 (an increase of 41%). In addition, the economic cost of rice increased from Rs 2,615.51 per quintal in 2013-14 to Rs 3,723.76 per quintal in 2020-21 (an increase of 42%). The survey observes that revision of CIP to reduce the rising expenses on food subsidy bill. Industry and infrastructure The industrial sector is estimated to decline by 9.6% in 2020-21. Within the sector, highest decline is estimated in construction (12.6%) and mining (12.4%). The contribution of the industrial sector to GVA has declined from 32.5% in 2011-12 to 25.8% in 2020-21. The Index of Industrial Production (IIP) growth declined by 15.5% between April-November 2020 as compared to growth of 0.3% during same period in 2019. IIP is a measure of industrial performance that assigns a weight of 78% to manufacturing, 14% to mining, and 8% to electricity. Out of 407 items in IIP, the number of items which observed growth increased from 28 in April 2020 to 171 in November 2020, thereby, indicating a sharp economy recovery. The National Infrastructure Pipeline was launched with an investment plan of Rs 111 lakh crore over five years (2020-25). The project is aimed at increasing growth, competitiveness, and employment. The state governments, central government, and the private sector will invest 40%, 39%, and 21% in the project, respectively. The major share of the funds will be given to: (i) energy sector (24%), (ii) roads (18%), (iii) urban infrastructure (17%), and (iv) railways (12%). Service sector In 2020-21, the service sector is estimated to contract by 8.8% (with trade and hospitality contracting the most (21.4%)) as compared to 5.5% growth in 2019-20. Software services was the only sub-sector with positive growth (3.6%) in the period of April-September 2020. While the pandemic led to a global slowdown in trade, the Indian service sector export remained resilient. The net services export receipts in first half of 2020-21 was USD 41.67 billion, which is 3% higher than the service export receipts in first half of 2019-20 (USD 40.47 billion). Health The survey notes that Ayushman Bharat Pradhan Mantri Jan Arogya Yojana (AB-PM-JAY) enhanced health insurance coverage. The proportion of health insured households between 2015-16 to 2019-20 increased by 54% in states that implemented AB-PM-JAY and decreased by 10% for states which did not implement the scheme. During this period, infant mortality rate decreased by 20% in states that implemented AB-PM-JAY whereas in states that did not implement AB-PM-JAY, infant mortality rate declined by 12%. The survey further notes that better access to bare necessities (such as housing, water, sanitation, electricity, and cooking fuel) lead to an improvement in health indicators. India has one of the highest levels of out-of-pocket expenses as a share of total health expenditure. The survey observes that increasing the spending on public health from 1% of GDP to 2.5-3% of GDP will help in reducing the out-of-pocket expenses from 65% to 30%. The survey noted that mitigating information asymmetry in the healthcare sector will help in achieving lower insurance premiums and better welfare of people. It recommends setting up a regulator for the healthcare sector to prevent market failures due to information asymmetry (specifically in private healthcare sector). Banking sector During an economic crisis, adoption of regulatory forbearance could help ease stress in the financial sector. Regulatory forbearance includes measures such as allowing banks to restructure certain loans rather than change the asset classification. The survey suggests that such measures must be withdrawn in a timely manner. It was noted that regulatory forbearance was adopted after the Global Financial Crisis in 2008 for seven years. This led to an increase in non-performing assets and reduced credit growth once the measures were withdrawn. The survey observed that withdrawal of regulatory forbearance must be followed by a review of the quality of the bank’s assets, and capitalisation to ensure growth in lending. Credit Rating The survey noted that India’s credit rating does not reflect the country’s fundamentals in terms of GDP growth, inflation, government debt as a % of GDP, among others. It observed a bias in ratings against emerging economies like India and China. Credit rating maps the probability of default, reflecting the willingness and ability of borrower to meet debt obligations. India has no history of sovereign default (demonstrating willingness to pay), and the foreign exchange reserves are greater than the total external debt of the country (demonstrating ability to pay). Poor sovereign credit ratings have adverse impact on inflow of foreign investments. Innovation India ranked 48 in Global Innovation Index in 2020, which makes it first among Central and South Asian countries, and third among the lower middle-income economies. However, India’s gross domestic expenditure on research and development (GERD) is lowest amongst larger economies. India spends 0.7% of GDP on GERD as compared to the expenditure of over 2% of GDP by China and over 2.5% of GDP in the United States of America. Currently, the government sector contributes 56% of the total GERD, which is higher than the contribution of the government sector (20%) in top ten economies (such as China, United Kingdom, and Japan). The contribution by business sector to GERD in India is 37%, which is significantly lower than the contribution of the sector in other large economies (68%). The survey observes that GERD should be increased to over 2% of GDP by enhancing research and development facilities, especially in the private sector.\nDISCLAIMER: This document is being furnished to you for your information. You may choose to reproduce or redistribute this report for non-commercial purposes in part or in full to any other person with due acknowledgement of PRS Legislative Research (“PRS”). The opinions expressed herein are entirely those of the author(s). PRS makes every effort to use reliable and comprehensive information, but PRS does not represent that the contents of the report are accurate or complete. PRS is an independent, not-for-profit group. This document has been prepared without regard to the objectives or opinions of those who may receive it.", "pred_label": "__label__POS", "pred_score_pos": 0.7813881635665894} +{"content": "04-01-2021\nJennifer Freyd was a fully tenured psychology professor at the University of Oregon. A graduate of Stanford and Cornell, she specialized in trauma studies, taught students, oversaw a research lab, edited a preeminent journal, and served on several University committees. She filed a lawsuit asserting that the University paid her significantly less than her male colleagues of equal rank and seniority.\nWhile working at the University, other educational institutions reached out to her in an effort to persuade her to leave but she let them know she was not interested. Her husband also worked for the University of Oregon, and she wanted to continue her work there. Other institutions also reached out to her male colleagues at the University to recruit them. The University of Oregon responded to these recruitments by providing “retention raises” to these professors as an incentive to stay. Because Freyd was uninterested in leaving, the University of Oregon did not offer her a “retention raise.” As part of an unrelated records request, Freyd saw the salaries of the Psychology department; she was paid between $14,000 and $42,000 less per year than her male colleagues. She believes the “retention raises” accounted for much of the disparity. In her analysis, she found that even female faculty who were more receptive to offers from other institutions did not benefit in the same way from these raises.\nAfter a federal district court dismissed the case, the Ninth Circuit revived Freyd’s Equal Pay Act claim. The University argued the male professors performed different research, ran different labs, obtained funding from different sources, and sat on different committees, making their work easily distinguishable from Freyd’s. However, the circuit court concluded a reasonable jury could decide that the male comparators “perform a common core of tasks” and did substantially the same work. Each individual taught, researched, advised students, and participated in University committees. The court stated it was unable “\nas a matter of law to pronounce their responsibilities so unique that they cannot be compared for purposes of the Equal Pay Act.” To ensure the Act is “broadly remedial” and will be workable across industries, the appellate court held it should be presented to a jury.", "pred_label": "__label__POS", "pred_score_pos": 0.755873441696167} +{"content": "Punarnava – The Renewing Ayurvedic Herb Punarnava is one of the best known diuretic herbs in Ayurveda. The name Punarnava means ‘one that renews the old body’ indicating its potent rejuvenative properties particularly in heart and kidney issues. It is a strong digestive herb that is beneficial in sluggish and slow digestion. However, as it functions by absorbing fluids from the digestive system, it can be very constipating in excess and therefore caution must be exercised whilst using Punarnava. Since it works efficiently in reducing adipose tissue and balancing the urinary system, it is also an effective herb in cases of diabetes. It has a strong action on the kidneys by reducing excess fluids, swelling and edema hence making it an excellent herb in bladder infections and nephritis....", "pred_label": "__label__POS", "pred_score_pos": 0.8677701950073242} +{"content": "Special Economic Zones and Their EffectsWhile Cambodia has introduced numerous policies in order to attract FDI, its Special Economic Zone (“SEZ”) policy is arguably one of the most instrumental measures in place. Governed by the Law on Investment, SEZs are geographical areas designated by the RGC within Cambodian borders where business and trade regulations differ from those that apply to the rest of the country. Featuring streamlined administrative procedures and high-quality infrastructure, the SEZs aim to facilitate export development, create employment, and promote diversification from traditional sectors through FDI. Surely, such investment-friendly environment has attracted significant FDI inflow and resulted in economic diversification to an extent, attracting a broader spectrum of foreign investment in Cambodia’s main industries.\nNevertheless, not all projected benefits of the SEZs may materialize. For instance, the RGC projects that the SEZs will, in the long-term, facilitate local development and disseminate technology to the rest of the Cambodian economy. However, according to the OECD, insufficient physical and economic infrastructure outside the SEZs may render such spillover benefits unattainable. Additionally, the OECD notes that Cambodia’s domestic small and medium-sized enterprises’ lack of capacity or skill to benefit and comply with certain international standards can deter foreign investors from engaging in business partnerships.\nMoreover, experts and stakeholders have documented negative socioeconomic and environmental consequences. Despite some socioeconomic gains, real wages have not changed significantly while land values in the SEZs have increased. This suggests that landowners have disproportionately benefited from the SEZ program compared to the workers, exacerbating the current economic inequality in Cambodia. Furthermore, many SEZs are associated with biodiversity oppression driven by the proliferation of habitat destruction and black-market trades in wildlife products.\nFor more specific information regarding SEZs or any other topics pertinent to my briefing memo, visit https://opendevelopmentcambodia.net/.\nPostludeAfter the first meal, lights are dimmed, in order to institute a relaxing atmosphere in which passengers can readily neglect time that is passing by ever so slowly. For many, this lighting seems operative of its intended effect, as they start drifting off, successfully entering the state best known for losing our sense of time. However, it still does not permeate its effect through the stubborn some, including myself, who are sleeplessly sitting through the ironic boredom of crossing the skies of multiple continents. With approximately ten hours left to go on this return flight from Incheon to Dulles, countless thoughts have already visited and left my mind in an attempt to divert my attention from this tedium. Although most thoughts were new or transient, the one regular that always pays me a visit in this setting surely didn’t forget to do so again this time. This visitor, as alluded in my third blog post, is the continued contemplation about my sense of “home.”\nPerhaps it is the momentary placement of myself in this neutral zone—where I am not physically restrained by borders of any nation for approximately 14 hours—that enables a more impartial self-assessment.\nAs always, when I arrived at my childhood home and was once again in the presence of my family, I immediately sensed the unique familiarity and comfort that awaited. These feelings lasted through my entire stay in Korea and stayed behind once I set my foot on this plane. Undoubtedly, they had a different nuance from the familiarity and comfort that my Arlington residence induces in ways that are challenging to elaborate. Regardless, I know with certainty that my time in both places have constituted a significant portion of my identity, and both nuances have become parts of the feeling that I like to call home, equally. In this regard, maybe trying to designate a place to call home is futile. Maybe, the word “home” cannot be defined in the first place, like love or happiness, which are abstract concepts of emotions that contain meanings beyond the words of their definitions. So, maybe, what matters the most is the sense of home—something along the lines of a feeling of belongingness, comfort, and affinity that you yearn for after a long day or a journey. Despite its varying definitions, maybe this sense is universal.", "pred_label": "__label__POS", "pred_score_pos": 0.9396507143974304} +{"content": "Projects per year\nAbstract\nWhen a colloid is mixed with a depletant such as a non-adsorbing polymer, one observes attractive effective interactions between the colloidal particles. If these particles are anisotropic, analysis of these effective interactions is challenging in general. We present a method for inference of approximate (coarse-grained) effective interaction potentials between such anisotropic particles. Using the example of indented (lock-and-key) colloids, we show how numerical solutions can be used to integrate out the (hard sphere) depletant, leading to a depletion potential that accurately characterises the effective interactions. The accuracy of the method is based on matching of contributions to the second virial coefficient of the colloids. The simplest version of our method yields a piecewise-constant effective potential; we also show how this scheme can be generalised to other functional forms, where appropriate.\nFingerprintDive into the research topics of 'Coarse-grained depletion potentials for anisotropic colloids: application to lock-and-key systems'. Together they form a unique fingerprint. Projects 1 Finished\nWilding, N. & Jack, R.\n1/05/12 → 30/04/15\nProject: Research council", "pred_label": "__label__POS", "pred_score_pos": 0.9627202153205872} +{"content": "CDC Director Approves Booster Dose of Pfizer COVID-19 Vaccine for Older Adults, At-Risk Workers This information is provided by national senior living association partner, Argentum.\nCDC Director Rochelle Walensky endorsed Pfizer COVID-19 vaccine booster shots for people 65 years of age and older and residents in long-term care settings, as well as people 50-64 years of age with underlying medical conditions—citing that these groups “should” receive the shot. Additionally, individuals 18-49 with underlying medical conditions and those 18-64 who are at increased risk due to an occupational or institutional setting “may” receive the shot, according to the CDC. All Pfizer booster shots should be administered at least 6 months after the Pfizer primary series of vaccines have been completed.\nWalensky’s approval for boosters for at-risk workers strayed from the recommendations made and voted on (9-6) by the Advisory Committee on Immunization Practices (ACIP), a CDC advisory panel, on Thursday afternoon. Those who voted “no” for at-risk workers signaled a lack of evidence to support that people were at higher risk of severe COVID-19 due to their profession. However, the CDC shared that there is emerging evidence indicating that vaccine effectiveness is waning among health care and other frontline essential workers. Due to this, the CDC recommends that adults at high risk of disease due to their work or workplace get the Pfizer booster based on individual benefits and risks. More data and FAQs from the CDC is attached.\nEarlier in the week, the FDA’s Vaccines and Related Biological Products Advisory Committee met and voted unanimously to recommend Emergency Use Authorization (EUA) for a booster dose of the Pfizer COVID-19 vaccine to be given six months after full vaccination for those 65 and older and those at high risk of severe illness due to COVID-19. They also informally suggested that health care workers be considered for the booster dose. The Pfizer COVID-19 vaccine received full FDA approval for those 16 years of age and older on August 23, 2021.\nThe CDC has shared that “individuals can self-attest (i.e. self-report that they are eligible) and receive a booster shot wherever vaccines are offered. This will help ensure there are not additional barriers to access for these select populations receiving their booster shot.” Additionally, the CDC has indicated it will be reviewing data in the coming weeks to make recommendations regarding booster doses for the Moderna and Johnson & Johnson vaccines. Argentum’s Vaccine Task Force is finalizing guidance for members on resources for booster implementation in senior living communities, and that guidance is forthcoming. We are continuing to stress to the administration the importance of continuing to prioritize senior living residents and employees in future decisions and encouraging them to do everything they can to support the resourcing needed for effective and efficient implementation of the additional doses.", "pred_label": "__label__POS", "pred_score_pos": 0.8948085308074951} +{"content": "High frequency indicators for the UK suggest activity collapsed in mid-March and has shown no signs of recovery since. Our forecast assumes a double-digit decline in GDP in H1 2020 even if coronavirus restrictions are gradually eased from mid-May. Nothing in the high frequency data refutes this.\nCommuting and electricity demand fell sharply after the lockdown. Even allowing for widespread working from home, this is indicative of a steep drop in activity. Forced closures caused retail and leisure activity to collapse, and even essential shops have seen much lower footfall since panic-buying subsided.\nWeekly universal credit claims ran at 11x normal levels for a week either side of the introduction of the lockdown. While claims have since fallen back, the spike indicates the number of households suffering financial stress.", "pred_label": "__label__POS", "pred_score_pos": 0.5070153474807739} +{"content": "Australia is experiencing extreme heat and torrential rains. It is a mixing combination, but it is as the weather pattern it is.\nKeeping cool is a challenge and avoiding the rains is a strenuous task. So, as the world experiences the changes in weather, it is time to commence climatizing to cope with the change.\nChange is happening so rather than complaining we need to adjust. Regardless of the excuses or debate we need to make a change.\nOur species will survive if we start now to make adjustments.\nHappy Celeritism", "pred_label": "__label__POS", "pred_score_pos": 0.5162848234176636} +{"content": "As interest rates remain low and could continue to trend lower in the foreseeable future, it’s prudent to bet on reliable dividend-paying stocks to generate a worry-free inflow of cash.\nWhile the list of top-quality dividend-paying Canadian stocks is long, a few offer monthly payouts. Let’s look at five such monthly paying stocks you can consider buying now. I have restricted the list to stocks that are trading below $50 and have sustainable payouts.\nPembina Pipeline\nSpeaking of monthly paying dividend stocks,\nPembina Pipeline (TSX:PPL)(NYSE:PBA) comes first to my mind. This energy infrastructure company has distributed over $10 billion in dividends since its inception. In the last decade, it has increased the dividend by a CAGR of 5%. It pays a monthly dividend of $0.21 a share and offers a stellar yield of 6.0%.\nIt is interesting to note that Pembina’s dividend payouts are covered through its resilient, fee-based cash flows. Its diversified and highly contracted assets consistently generate strong fee-based cash flows and drive higher payments. I believe its contractual framework, exposure to multiple commodities, solid backlogs, and growth projects will continue to fuel its cash flows and drive enhanced dividend payments.\nNorthWest Healthcare NorthWest Healthcare’s (TSX:NWH.UN) low-risk business, diversified healthcare real estate assets, higher occupancy, and long lease expiry term are the reasons why one should consider buying this monthly paying dividend stock. It is worth noting that most of NorthWest’s tenants are government-backed, adding stability to its business. Further, the majority of its rent is inflation-indexed, which is very encouraging.\nNorthWest Healthcare is expanding in high-growth markets. Meanwhile, its strategic acquisitions, robust balance sheet, and focus on deleveraging augur well for growth and are likely to support its monthly dividend payments. It pays a monthly dividend of $0.067 per share, reflecting a high yield of 6.0%.\nAltaGas AltaGas (TSX:ALA), in my opinion, is an excellent stock that offers a monthly dividend of $0.083 per share. Meanwhile, it yields about 3.9% at current price levels, which is lucrative. Thanks to its regulated utility assets and high-growth midstream operations, AltaGas generates solid cash flows that drive its dividend payments.\nThe continued increase in its rate base, improved energy demand, higher export volumes in its midstream business, and increased utilization rate will likely support its future growth as well as its payouts. Further, customer acquisitions, cost efficiencies, and the integration of Petrogas bode well for future growth.\nTransAlta Renewables\nLike AltaGas,\nTransAlta Renewables (TSX:RNW) is another attractive monthly dividend-paying stock that currently yields about 4.9%. It has annually increased its dividend at a CAGR of 3% since 2013 and targets a sustainable payout ratio of 80-85%.\nTransAlta could continue to reward its shareholders with steady monthly payouts thanks to its low-risk business, highly contracted renewable power assets, and predictable cash flows. Meanwhile, its diversified asset base, strategic acquisitions, and strong balance sheet could continue to drive its earnings and dividend payouts.\nNorthland Power\nThe last stock on my list is\nNorthland Power (TSX:NPI). This renewable power company has consistently paid monthly dividends, while its payouts are reliable and sustainable in the long run. It offers a monthly dividend of $0.10 per share and yields about 2.9% at current price levels.\nNorthland Power’s diversified assets and long-term agreements will likely generate predictable cash flows. Furthermore, an improving energy outlook, robust development projects, capital investments, and increasing installed capacity could boost its free cash flows and support future dividend payouts.", "pred_label": "__label__POS", "pred_score_pos": 0.6469148993492126} +{"content": "The recommendations the InfantRisk Center provides are not meant to replace medical advice from your physician. The ultimate decision to breastfeed while taking medications should be based on an informed decision including available data, discussions between a mother, her physician, and the infants’ pediatrician. The decision to take medications during pregnancy should be based available data and a discussion between a mother and her OB/GYN.\nIt should be safe to breastfeed after Botox. Botox is almost completely sequestered in the skin and does not even reach the plasma compartment. Also, it is far too large a molecule to enter milk. I'd suggest you wait a few hours, pump and discard the milk after about 4 hours and then return to breastfeeding.", "pred_label": "__label__POS", "pred_score_pos": 0.9098109006881714} +{"content": "The state of Utah does not follow the Daubert or Frye for the admissibility of expert witness testimony, but instead follows the Rimmasch test. Haupt v. Heaps, 131 P.3d 252 (Utah Ct. App. 2005). The Rimmasch test focuses on the reliability of the expert’s testimony, particularly in cases where the expert utilized “novel scientific principles or techniques” to reach its conclusions. Id. The Rimmasch test has been embodied by Utah’s Rule of Evidence, Rule 702, which stands as the overarching rule for the admissibility of expert witness testimony. State v. Sheehan, 273 P.3d 417 (Utah Ct. App. 2012). Utah’s rule of evidence states that testimony is admissible if there is a “threshold showing that the principles or methods that are underlying the testimony (1) are reliable, (2) are based upon sufficient facts or data, and (3) have been reliably applied to the facts.” UTAH R. EVID. 702 (2017). The portion of the rule that embodies the Rimmasch test is (c), and states that the “threshold showing … is satisfied if the underlying principles or methods, including the sufficiency of facts or data and the manner of their application to the facts of the case, are generally accepted by the relevant expert community.” Id.", "pred_label": "__label__POS", "pred_score_pos": 0.5504292249679565} +{"content": "Effective tax management can result in significant cost and cashflow savings for your business. Here are some tax tips that every business should consider. Effective management of the business taxation affairs can reduce costs and enhance cash flow Be aware of different minimum wage rates for various categories of employees Consideration of dividends v salaries for emoluments of business owners Consider tax effective pension contribution Explore opportunity to employ family members and use Personal Tax Allowances Explore Research & Development Tax Credits Consider forming a Group structure", "pred_label": "__label__POS", "pred_score_pos": 0.9525783658027649} +{"content": "by: Sara Middleton, staff writer | August 19, 2021\n(NaturalHealth365) According to the U.S. Centers for Disease Control and Prevention (CDC), the new mRNA COVID shot available under Emergency Use Authorization (EUA) can cause a variety of adverse effects, including myocarditis, a type of heart inflammation. The CDC also claims these cases are typically mild.\nBut dismissing these cases as “mild” does not capture the whole picture. Let’s explore a recent Children’s Health Defense interview with a mother explaining her son’s struggle with myocarditis following his Pfizer injection.", "pred_label": "__label__POS", "pred_score_pos": 0.9999567866325378} +{"content": "Asian ScienceCitation Index is committed to provide an authoritative, trustedand significant information by the coverage of the most importantand influential journals to meet the needs of the global scientificcommunity.\nAbstract: Activation of CD4+ T cells helps establish and sustain other immune responses. We have previously shown that responses against a broad set of nine CD4+ T-cell epitopes were present in the setting of lymphocytic choriomeningitis virus (LCMV) Armstrong infection in the context of H-2d. This is quite disparate to the H-2b setting, where only two epitopes have been identified. We were interested in determining whether a broad set of responses was unique to H-2d or whether additional CD4+ T-cell epitopes could be identified in the setting of the H-2b background. To pursue this question, we infected C57BL/6 mice with LCMV Armstrong and determined the repertoire of CD4+ T-cell responses using overlapping 15-mer peptides corresponding to the LCMV Armstrong sequence. We confirmed positive responses by intracellular cytokine staining and major histocompatibility complex (MHC)-peptide binding assays. A broad repertoire of responses was identified, consisting of six epitopes. These epitopes originate from the nucleoprotein (NP) and glycoprotein (GP). Out of the six newly identified CD4+ epitopes, four of them also stimulate CD8+ T cells in a statistically significant manner. Furthermore, we assessed these CD4+ T-cell responses during the memory phase of LCMV Armstrong infection and after infection with a chronic strain of LCMV and determined that a subset of the responses could be detected under these different conditions. This is the first example of a broad repertoire of shared epitopes between CD4+ and CD8+ T cells in the context of viral infection. These findings demonstrate that immunodominance is a complex phenomenon in the context of helper responses.", "pred_label": "__label__POS", "pred_score_pos": 0.9345909357070923} +{"content": "Bispectral index in calves anesthetized with xylazine, midazolam, ketamine, isoflurane and subjected to continuous rate infusion of lidocaine\nAraújo, Marcelo Augusto deBeloti, Carolina Aparecida CarlinDeschk, MaurícioArruda, André Moreira MartinsCheng, Lu ShiAlbuquerquer, Verônica Batista deSantos, Paulo Sergio Patto dos\nPURPOSE: To assess the bispectral index (BIS) and recovery in calves anesthetized with xylazine, midazolam, ketamine and isoflurane and subjected to CRI of lidocaine. METHODS: Xilazine was administered followed by ketamine and midazolam, orotracheal intubation and maintenance on isoflurane using mechanical ventilation. Lidocaine (2 mg kg-1 bolus) or saline (0.9%) was administered IV followed by a CRI (100 µg kg-1 minute-1) of lidocaine (L) or saline (C). Were recorded BIS, heart rate (HR), mean arterial pressure (MAP) and rectal temperature (RT) before administration of premedication (TB) and 15 minutes after (TX), before administering lidocaine (T0) and 20, 40, 60 and 80 minutes after the start of the CRI . Time do sternal recumbency (SRE) and standing (ST) and plasma lidocaine concentration also evaluated. RESULTS: In both treatments BIS decreased significantly at all times compared to TB. TX was higher than the subsequent times. HR decreased from baseline at all times and decreased from T40 in L compared to C. SRE was higher in L compared to C. CONCLUSIONS: Bispectral index values were consistent with the degree of hypnosis of the animals. Lidocaine did not potentiate isoflurane anesthesia assessed by BIS in unstimulated calves anesthetized with constant E´Iso. Lidocaine increased the time to sternal recumbency.(AU)Texto completo", "pred_label": "__label__POS", "pred_score_pos": 0.5871045589447021} +{"content": "France adopted its new Law on Transparency, the Fight against Corruption and Modernization of Economic Life which will bring France’s anti-corruption regime up to the highest European and international standards in its fight against corruption.\nThe Supreme Court of Canada held that the World Bank Group cannot be compelled to turn over volumes of investigation materials in a Canadian prosecution.\nWhen senior government prosecutors discuss their white collar enforcement priorities, the prosecution of individuals frequently tops their list. However, holding company employees criminally responsible for corporate misconduct is easier said than done.\nAt the annual “SEC Speaks” conference on February 19, 2016 in Washington, DC, the head of the SEC’s FCPA Unit, Kara Brockmeyer, warned pharmaceutical companies that their industry will be under renewed scrutiny in 2016.\nThis event will explore the sanctions regimes of development banks, in parallel with those of the U.S. Department of Justice and Securities and Exchange Commission. A panel of experts will share observations on the evolving sanctions landscape and will provide practical guidance to companies in order to avoid unwanted enforcement scrutiny.\nOn November 1, 2015, several important amendments to the U.S. Sentencing Guidelines became effective. The amendments include changes to the guidelines governing fraud and economic crime that will have a significant impact on the prosecution of individuals for a wide range of conduct. We summarize several of the amendments that could have a significant impact on sentencing and settlement negotiations in FCPA cases.\nHolding company employees criminally responsible for corporate misconduct is easier said than done. We analyze why the Justice Department, which routinely concludes multimillion-dollar criminal settlements with the world’s largest corporations, struggles to convict individuals associated with the alleged misconduct?\nFrance’s Finance Minister, Michel Sapin, presented the framework of a bill which would create a new anti-corruption authority and introduce U.S.-style monitorships into French law.\nOn June 18, the U.S. Justice Department (“DOJ”) announced the results of a nationwide sweep conducted by the Medicare Fraud Strike Force which led to the arrest of more than 240 healthcare providers alleged to be involved in over $700 million in false billings for Medicare services. Earlier in the…\nAs regulators and prosecutors across many jurisdictions increasingly cooperate in cross-border anti-corruption enforcement efforts, the importance of an effective, globally oriented anti-bribery compliance program cannot be overstated. Parallel enforcement actions along with greater scrutiny of corporate compliance programs serve as a sobering reminder of the persistent efforts of regulators. With…", "pred_label": "__label__POS", "pred_score_pos": 0.5635310411453247} +{"content": "Across democracies, education predicts electoral participation and political interest. Here, German students on the pre-vocational and pre-academic educational tracks are compared to show how these differences emerge, and thus indicate how they can be addressed. In a Preliminary Study, a large dataset (3747 participants) revealed that there is a gap in political interest between the tracks, and that this predicts a gap in voting intentions. Study 1 (228 participants) tested three mediators of the relationship between educational tracks and voting intentions. Differences in civic understanding primarily explained the link between educational track and voting intentions. Lastly, in Study 2, 23 semi-structured interviews explored how limited civic understanding constrains political engagement among students on the pre-vocational track, indicating that a narrow understanding of power and a lack of sociological imagination are key. The finding that the gaps emerge due to differences in civic understanding, which is teachable, suggests that schools can play an effective role in addressing them. Limitations and implications are discussed.", "pred_label": "__label__POS", "pred_score_pos": 0.9972344636917114} +{"content": "Among the members of the International Monetary Fund (IMF), 110 countries examine the central bank’s digital currencies (CBDCs), revealed the fund’s president and CEO Kristalina Georgieva at an event hosted by Bocconi University in Italy. Speaking externally to the public, she noted that the key challenge for monetary authorities now is to guarantee the interoperability of these currencies.\nAccording to Georgieva, a major consideration is whether state-sponsored digital currencies can serve as a means of exchange that the public trusts, Reuters reported on Tuesday. Other questions that politicians need to answer are whether CBDCs can contribute to domestic economic stability and how they would fit within the international regulatory framework introduced by organizations such as the Bank for International Settlements (BIS).\nThe BIS Innovation Hub is leading several projects to test the use of government-issued digital currencies in international transactions, such as a collaboration between the Reserve Bank of Australia, Bank Negara Malaysia, the Monetary Authority of Singapore and the South African Reserve Bank. These also include joint trials conducted by China, Hong Kong, Thailand and the UAE as well as a wholesale CBDC test conducted by the Banque de France and the Swiss National Bank.\nReferring to cooperation between international financial organizations and national monetary authorities concerning CBDCs, Kristalina Georgieva further stated:\n“It is very impressive how much the international community, central banks, institutions like ours are now actively involved in ensuring that money in this fast-paced world of digitalisation is a source of confidence and helps the economy to function rather than [being] a risk “.\nThe head of the IMF stressed that she considers digital currencies issued by central banks as the most reliable form of digital money, while noting that she has difficulty thinking of cryptocurrencies as money. “De facto assets” such as bitcoin are not supported by assets that keep their value stable and can rise and fall sharply, Georgieva elaborated and insisted:\np style = “box-sizing: border-box; margin-bottom: 1rem; margin-top: 0px;”> “In the history of money, it’s hard to think of them as money”.\nIn his speech at the Italian academic event, the IMF chief also spoke about Europe’s efforts to address the challenges posed by the proliferation of Covid-19. Kristalina Georgieva noted that the old continent is now more prepared to avoid another debt crisis like the one with Greece after the last global financial crisis. However, she stressed that governments need to plan their course carefully when switching to fiscal consolidation in the medium term so that they can erase the debt burden associated with the pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.9567201137542725} +{"content": "Going on a diet is never an easy task, but it’s valuable for helping you stay healthy and in shape. However, a cookie-cutter diet isn’t often the best solution for everyone. Each person has unique needs, making it essential to ensure you’re choosing the right diet plan for you. The following questions will help you…", "pred_label": "__label__POS", "pred_score_pos": 0.9955162405967712} +{"content": "October 8, 2021EETC and National Grid SA are developing an interconnection project that aims to connect the grids of Egypt and Saudi Arabia. The project entails the construction of a ±500 kV multi-terminal high voltage direct current (HVDC) link from Badr in Egypt to El-Madinah El Munawara via Tabuk in Saudi Arabia. The interconnector will have a transfer capacity of 3,000 MW. It will allow Egypt and Saudi Arabia to capitalise on the differences in their peak power demand times, facilitate trade, and lead to cost savings of around USD3.7 billion.\nSeptember 9, 2021The 68-km-long, 132 kV double-circuit transmission line will run from Olkaria to Narok in Kenya. It also enatils construction of the a new 132/33 kV substation at Narok and extension of the existing Olkaria substation. The line will serve as the backbone for increasing the electricity access within the Narok country and its surrounding areas.\nAugust 9, 2021The project entails the construction of a 102-km-long, 230 kV double-circuit transmission line from Semera (Ethiopia) to Galafi (Djibouti Border), a 190-km-long, 230 kV double-circuit transmission line from Galafi to Nagad in Djibouti, and a 170-km-long, 230 kV double-circuit transmission line with one circuit strung from Kombolcha to Mile, and then to Semera in Ethiopia.\nJune 10, 2021The 225/30 kV Projetd’ Interconnexion Électrique Guinée Mali (PIEGM) or the Guinea–Mali Electric Interconnection Project, involves the construction of a 714-km-long, 225 kV transmission line between Guinea and Mali, of which 590 km is in Guinea and 124 km in Mali.\nMarch 11, 2021The 500 kV high voltage direct current (HVDC) line aims to link the power grids of Ethiopia and Kenya, create power-sharing between the two countries, reduce energy costs, and promote sustainable and renewable power generation.\nFebruary 9, 2021The Lusaka Power Transmission and Distribution Network (LPTDN) project being developed by ZESCO Limited aims to reinforce and upgrade the power transmission and distribution (T&D) infrastructure in the Lusaka area.\nNovember 5, 2020The project aims to connect the electricity grids of Egypt, Cyprus and Greece through a subsea direct current (DC) cable and high voltage direct current (HVDC) onshore converter stations.\nJuly 13, 2020The 330 kV North Core Project is a 330 kV transmission line from Birnin Kebbi (Nigeria) to Ouagadougou (Burkina Faso), passing through Zabori (Niger) and Niamey (Niger) with a T-off to Malanville (Benin).\nApril 8, 2020The project involves the construction of 1,024-km-long, high voltage lines between Ngaoundéré, Maroua, in Cameroon, and N’Djamena in Chad, along with associated substations and distribution networks for rural electrification along the lines.", "pred_label": "__label__POS", "pred_score_pos": 0.7664058804512024} +{"content": "KEY POINTS Solar winds destroyed the atmosphere of Mars The magnetosphere protects Earth from solar winds Radiation from solar winds can increase cancer rates among humans\nExperts discussed how solar winds emitted by the Sun can be dangerous. Aside from destroying the atmospheres of planets, these solar emissions can also kill humans.\nSolar winds, which are highly charged particles ejected from holes in the Sun’s atmosphere, hit Earth regularly. Fortunately, the solar emissions that reach Earth are only minor and are not powerful enough to affect the planet’s magnetic field or cause electrical disruptions.\nExtreme cases of solar winds, on the other hand, can be devastating for a planet. One example that showcases the destructive capabilities of solar winds is Mars. As indicated in scientific reports, Mars previously had ideal conditions that could have supported life.\nHowever, powerful solar winds from the Sun stripped the planet’s atmosphere and turned it into a hostile world. According to planetary scientist Arun Prasaad Gunasekaran, since Mars did not have a magnetic field to protect it from solar winds, its atmosphere became vulnerable to the effects of the solar emissions.\n“For Mars, the magnetosphere is extremely weak (maybe gone) because of the absence of the internal dynamo,” he stated in a post on Quora. “So, the solar winds can breach the magnetosphere and can rip the atmosphere due to their kinetic energy and momentum.”\nUnlike Mars, Earth has a magnetosphere, which means its atmosphere is relatively safe from being stripped away by solar winds. However, without the magnetosphere, the entire planet and its inhabitants will be directly exposed to the harmful effects of solar winds, such as radiation.\nAccording to electrical engineer Harry Kier, the intense ultraviolet radiation from solar winds could cause accelerated cancer rate among humans, which could be extremely fatal.\nAside from an increased death rate caused by cancer, intense solar winds could also knock out communication and electrical grids, which could have a huge impact on countries.\n“Without the Earth’s magnetic field to deflect it, this radiation would cause an increased cancer rate in we humans,” Kier explained in a statement. “Extreme solar flares can disrupt electric and communication grids. Radiation from the sun increases the risk of cancer in space travelers.”", "pred_label": "__label__POS", "pred_score_pos": 0.6016126871109009} +{"content": "Artificial Intelligence (AI) applications continue to expand opportunities for humankind’s progress and to achieve the Sustainable Development Goals. UNESCO is working to harness these opportunities in its fields of competence and has been leading reflections around pressing concerns related to AI’s rapid development, from a Human Rights and ethics perspective. These range from AI’s role in the futures of education to the omnipresent challenges of disinformation and hate speech online.\nThis article was originally published on UNESCO website. Please follow the link to read more.", "pred_label": "__label__POS", "pred_score_pos": 0.8480849266052246} +{"content": "Soil salinization has been a topic due to the widespread recognition of the food crisis and the shortage of cultivated land resources in arid regions. Unfortunately, the evolution of soil salinization under the background of landscape dynamics is rarely addressed due to the lack of spatial coupling techniques. Recent developments in soil science and remote sensing technology provide the possibility for accurate management of land resources. This study aims to explore the spatiotemporal variations of soil salinization by coupling the spatial distribution of soil salinization and landscape patterns in the irrigated northern slopes of Tianshan Mountains. We graded soil salinization levels based on analytic hierarchy process (AHP) method. The results indicated that the proportion of salinized cultivated land in 2014 (32.11%) was higher than that in 2005 (28.11%). We argue that simply quantifying the changes of soil salinization can neither accurately reflect the effectiveness of salinized cultivated land management nor meet the need for land resource planning. In response to these shortcomings, the evolution of soil salinization was explored in three categories, i.e., \"stable cultivated land\", \"increased cultivated land\", and \"decreased cultivated land\". We found that the proportion of soil salinization in stable cultivated land has dropped considerably from 38.11% in 2005 to 29.22% in 2014. This number in the increased cultivated land (59.11%) is much higher than that of the whole study area. These results are expected to benefit local authorities and assist in alleviating the food crisis in arid regions.", "pred_label": "__label__POS", "pred_score_pos": 0.9769408106803894} +{"content": "Philipp Lorenz-Spreen, Stephan Lewandowsky, Cass R. Sunstein & Ralph Hertwig in Nature: “Public opinion is shaped in significant part by online content, spread via social media and curated algorithmically. The current online ecosystem has been designed predominantly to capture user attention rather than to promote deliberate cognition and autonomous choice; information overload, finely tuned personalization and distorted social cues, in turn, pave the way for manipulation and the spread of false information. How can transparency and autonomy be promoted instead, thus fostering the positive potential of the web? Effective web governance informed by behavioural research is critically needed to empower individuals online. We identify technologically available yet largely untapped cues that can be harnessed to indicate the epistemic quality of online content, the factors underlying algorithmic decisions and the degree of consensus in online debates. We then map out two classes of behavioural interventions—nudging and boosting— that enlist these cues to redesign online environments for informed and autonomous choice….(More)”.", "pred_label": "__label__POS", "pred_score_pos": 0.6571729779243469} +{"content": "First Paragraph\nMay 15, 2003 marked the fiftieth anniversary of a paper published in the journal I that revolutionized our thinking about one of the fundamental scientific questions that confronts humanity-how did life began on Earth? The paper was authored by Stanley L. Miller (1953), at that time a graduate student of Nobel Laureate Harold Urey’s at the University of Chicago. The experiment described in his paper demonstrated how, by using a simple apparatus designed to mimic the ocean-atmosphere system of Earth, could be used to synthesize essential biological compounds such as amino acids. If a similar type of process had taken place on early Earth, this could have produced the raw materials needed for the origin of life.", "pred_label": "__label__POS", "pred_score_pos": 0.8558554649353027} +{"content": "Every vehicle we sell at Henry Curtis Ford comes with a spare tire. We want our customers to feel confident and safe when on the road. Did you know that all spare tires aren't the same? There are two main types. Here's what you should know about the difference between a compact temporary spare and a regular spare tire.\nAs the name implies, compact temporary spare tires are best for smaller cars and aren't meant to be used long-term. You should seek a service station to replace this type of spare as soon as you're able. Also, you'll want to drive a bit slower than usual while using this kind of spare.\nA full-size spare tire, on the other hand, is more durable. It's also much larger. That's why you'll find these in trucks and SUVs. There's no need to change your driving habits with a full-size spare.", "pred_label": "__label__POS", "pred_score_pos": 0.5421390533447266} +{"content": "A study published in the European Journal of Cancer has provided further proof that cauliflower is the impressively versatile vegetable that should’ve never been so criminally underestimated. Conducted in 2015, the study found a considerable and surprising link between the consumption of fruit and white vegetables, namely cauliflower, and a lower risk of stomach cancer.\nThe researchers arrived at this conclusion by looking at over 32,000 gastric cancer cases and assessing their respective diets. During the initial information-gathering process, they found sodium and alcohol, specifically beer and liquor, to be particularly high-risk dietary factors.\nThey then discovered that foods rich in vitamin C tend to have a “protective effect” against gastric cancer. Such foods tend to be fruit and white vegetables that include potatoes, endives, onions, and our favorite, cauliflower.\nWhile we didn’t really need further reasons to enjoy the fibrous gem – hello, cauliflower pizza – the study serves as another reminder to continue using it in our recipes along with its fellow adaptable veggies.\nSource: Pop Sugar", "pred_label": "__label__POS", "pred_score_pos": 0.7215118408203125} +{"content": "Romania, Finland and Croatia recently published the Trio Programme for their upcoming EU Council Presidencies. The Trio Programme sets the joint political priorities for the presidencies and does not suggest radical changes, but puts emphasis on jobs and growth. European NGOs would like to see human rights based policies aiming at well-being within planetary boundaries.\nThe Cotonou Partnership Agreement is coming to an end in 2020. To ensure a fair ground leading to a “partnership of equals”, CONCORD has developed a list of recommendations, serving as a contribution from civil society to the ongoing EU-ACP negotiations to ensure mutually beneficial priorities.\nCONCORD took an active part in the AidEx conference in Brussels, that gathered more than 2.000 people from the aid and development. Here are the main takeaways from the debates, stands and discussions.\nIt is now a month since the second High-Level Meeting in Nairobi concluded. Looking back, was it a success? Certainly as the HLM concluded the civil society delegates were delighted with the outcome. Here is how it happened. Article written by Justin Kilcullen, former Co-Chair of CPDE.\nEuropean development NGOs urge the EU to agree an action plan that respects their promises on development and aid effectiveness\nToday, as the EU adopted its Common Position for the Global Partnership for Effective Development Cooperation High Level Meeting taking place in Nairobi on 30 November – 1 December, Europe’s development NGOs urged EU leaders to set themselves a clear timeline to achieve their commitments, crucial to delivering on the Sustainable Development Goals (SDGs).", "pred_label": "__label__POS", "pred_score_pos": 0.7240296602249146} +{"content": "I'm trying to derive the solution to a final producer with unit elasticity of substitution and a continuum of inputs (of measure $x$).\nShe minimizes input costs, given an output of $q$.\n$$ \\min_{\\{y(i)\\}_i, 0 \\leq i \\leq x} \\int_0^x p(i)y(i) di + \\lambda\\left[ \\log q - \\log A + \\int_0^x \\log y(i) di \\right] $$\nCombining two FOCs over $y(i)$ and $y(j)$, the shadow price drops out:\n$$ y(i) = p(j) \\frac{y(j)}{p(i)} $$\nMultiply with $w(i)$ and integrate, to get total labor cost on the left-hand-side:\n$$\\underbrace{\\int_0^x p(i)y(i)}_{C(x)} = p(j) y(j) x$$\nTaking logs:\n$$\\log y(j) = \\log(C(x)) - \\log p(j) - \\log x \\tag 1$$\nPlugging back into the production frontier:\n$$ \\log q = \\log A(x) + \\log(C(x)) - \\log x - \\underbrace{\\int_0^x \\log p(i) di}_{\\equiv P(x)}$$\nwhere I denote the price index as $P(x)$. Plugging back (1):\n$$ \\log q = \\log A(x) + \\log y(j) + \\log p(j) - P(x)$$\nor,\n$$ q = \\frac{A(x)y(j)p(j)}{P(x)} \\\\ y(j) = \\frac{P(x)}{p(j)}\\frac{q}{A(x)} $$\nSo, demand for each variety increases in total output $q$, decreases in productivity, and increases in the relative costs of variety $j$ compared to the total price index $P(x)$. This all appears to make sense.\nHowever, Acemoglu gets for $x=1$, and $A(1) = 1$\n$$ y(j) = \\frac{q}{p(j)}$$\nthat is, the price index does not appear in his equation, which you can find in his slides, slide. What am I missing?", "pred_label": "__label__POS", "pred_score_pos": 0.9897078275680542} +{"content": "Resective epilepsy surgery\nResective epilepsy surgery based on an invasive EEG-monitors performed with subdural grids (SDG) or depth electrodes (stereoelectroencephalography, SEEG) is considered to be the best option towards achieving seizure-free state in drug resistant epilepsy.\nDespite good outcomes from high-quality clinical trials, referrals of patients with seizures refractory to medical treatment remain infrequent\n1).\nThree RCTs (two adult RCTs and one pediatric RCT) consistently supported the efficacy of resective surgery as treatment for epilepsy with semiology localized to the mesial temporal lobe. In these studies, 58-100% of the patients who underwent resective surgery achieved seizure freedom, in comparison to 0-13% of medically treated patients. In another RCT, the likelihood of seizure freedom after resective surgery was independent of the surgical approach (transSylvian [64%] versus subtemporal [62%]). Two other RCTs demonstrated that hippocampal resection is essential to optimize seizure control. But, no significant gain in seizure control was achieved beyond removing 2.5 cm of the hippocampus. Across RCTs, minor complications (deficit lasting < 3 months) and major complications (deficit > 3 months) ranged 2-5% and 5-11% respectively. However, nonincapacitating superior subquadrantic visual-field defects (not typically considered a minor or major complication) were noted in up to 55% of the surgical cohort. The available RCTs provide compelling support for resective surgery as a treatment for mesial temporal lobe epilepsy and offer insights toward optimal surgical strategy\n2)\nComplete removal of the epileptogenic zone significantly increases the chances for postoperative seizure-freedom. In complex surgical candidates, delineation of the epileptogenic zone requires a long-term invasive video/EEG from intracranial electrodes. It is especially challenging to achieve a complete resection in deep brain structures such as opercular insular cortex\n3). Case series\nBelohlavkova et al. retrospectively reviewed data of pediatric patients operated in Motol Epilepsy Center between October 2010 and June 2020 who underwent resections guided by intraoperative visual detection of depth electrodes following SEEG. The outcome in terms of seizure- and AED-freedom was assessed individually in each patient.\nNineteen patients (age at surgery 2.9-18.6 years, median 13 years) were included in the study. The epileptogenic zone involved opercular insular cortex in eighteen patients. The intraoperative detection of the electrodes was successful in seventeen patients and the surgery was regarded complete in sixteen. Thirteen patients were seizure-free at final follow-up including six drug-free cases. The successful intraoperative detection of the electrodes was associated with favorable outcome in terms of achieving complete resection and seizure-freedom in most cases. On the contrary, the patients in whom the procedure failed had poor postsurgical outcome.\nThe reported technique helps to achieve the complete resection in challenging patients with the epileptogenic zone in deep brain structures\n4)\n81 patients with tuberous sclerosis complex (TSC) who had undergone resective epilepsy surgery at Sanbo Brain Hospital, between April 2004 and June 2019. They estimated the cumulative probability of remaining seizure-free and plotted survival curves. Variables were compared using Mann-Whitney U, Pearson's correlation, continuity correction, and Fisher's exact chi-square tests. Prognostic predictors were analyzed using log-rank (Mantel-Cox) tests and Cox regression models.\nAt the last follow-up, 48 (59.3%) patients were classified as International League Against Epilepsy Class 1 (including 14 patients who had seizures <3 times postoperatively on the same or different day and were seizure-free at all other times). The estimated cumulative probability of remaining seizure-free postoperatively was 69.0% (95% confidence interval [CI] 58.8-79.2%), 61.9% (95% CI 51.1-72.7%), and 55.0% (95% CI 42.8-67.2%) at 2, 5, and 10 years, respectively. The mean time of remaining seizure-free was 7.24 ± 0.634 years (95% CI 6.00-8.49); en bloc resection was an essential positive predictor of postoperative seizure freedom, as was age at seizure onset, regional interictal video-electroencephalography pattern, and temporal lobe surgery. The longer the seizure-free time, the less likely a relapse. Patients who postoperatively experienced seizures remained likely to recover.\n1) 2) 3), 4) 5)", "pred_label": "__label__POS", "pred_score_pos": 0.7541540265083313} +{"content": "How to Prevent Healthcare Workers from A Mental Breakdown? By:answerout95328756\nExtensive workload, pressure, and routine monotony can increase workers’ tiredness and fatigue, leading to healthcare problems. Medical professionals deal with even more amplified challenges while working in a highly demanding profession. For instance, unprecedented emergencies are common in their routine. As a result, they are more likely to encounter stress, depression, helplessness, and emotional instability. It is why the ongoing pandemic has complicated and aggravated healthcare problems even more. Even minor concerns have deteriorated to become complex issues.\nHowever, looking after personal well-being and catering to mental health can also be challenging during widespread emergencies.\nMost of the time, individuals are not even aware and capable of identifying the onset of their psychological issues. As a result, these issues keep worsening over time. It is why looking at the indications, prioritizing health, seeking assistance, and allowing yourself healing time are crucial measures. The following sections explore in-depth some of the ways to cater to psychic well-being and prevent the mental breakdown of the healthcare workers.\n1. Enhance awareness on psychic health\nUndeniably, enhancing awareness is an effective remedy to manage healthcare problems early on. Workers unaware of the repercussions of ignoring and postponing their psychological issues are more prone to compromise their health.\nHence, psychic health is also the focus of academic programs like Doctor of Nursing Practice (DNP). The program further enhances and diversifies nurses’ skillset to provide better and specialized psychological care. For instance, aspirants learn several skills, including administration, teamwork, clinical know-how, critical care, and psychotherapy. Additionally, they can also focus on specific healthcare specialties, including psychology and psychiatric disorders, to strengthen their proficiency and knowledge.\nMost importantly, dnp programs online offer the flexibility to carry out research and contribute to healthcare innovations. A relaxed study schedule enables them to participate in clinical procedures, observe physical and psychic healthcare challenges, and devise better healthcare solutions. Thus, individuals who understand the gravity of healthcare problems, patterns, indications, and complications can deal with them effectively.\n2. Observe existing healthcare problems\nA mental breakdown is the manifestation of chronic exhaustion and overload. It is also an indication of overlooking healthcare and personal requirements.\nThough everyone has a different mechanism to deal with the overload, coping with professional problems can be unmanageable. As a result, workers’ health deteriorates to advanced stages. Thus keeping track of your physical and mental requirements should be your concern, irrespective of the industry and work nature.\nWhen it is beyond your control and tolerance, discuss your healthcare issues and seek a specialist’s assistance. It is because mental problems often surface in a complicated manner and even involve physical symptoms that we may not be able to identify on our own.\nAdditionally, individuals overthink and attribute their mental problems to self-inadequacy and immaturity. As a result, identifying and categorizing psychic and physical problems can be challenging. In such cases, approaching an expert is a better option for understanding your concern, its seriousness, and suitable remedies. Thus observing and seeking professional help sooner can prevent mental breakdown and subsequent complications.\n3. Adjust workers’ duty schedule\nUndeniably, a well-structured schedule is one of the crucial factors in creating a balance in life. A balanced work schedule is even more necessary for extensively occupied healthcare professionals. Since their profession requires prioritizing work over personal matters, they usually delay personal obligations.\nHowever, such an attitude can produce toiling outcomes when your health is at stake. Thus a flexible schedule allows them the leverage to ponder over and cater to healthcare issues. Additionally, it improves their performance, personal achievement and enables them to provide better care to patients.\nOn the other hand, preoccupied and stressed workers cannot deliver premium services. They are more likely to commit performance errors and compromise patient health. As a result, hospitals cannot achieve their service delivery goals.\nMost importantly, mentally sick workers increase the burden on the healthcare, economic, and social sectors. Such multisector issues can lead to even more complex crises. Thus adjusting the work schedule can prevent such complications safely and even prevent workers’ psychic breakdown.\n4. Create avenues for mood alleviation\nSince the healthcare system continuously deals with healthcare problems, frequent exposure to miserable and helpless situations can be upsetting. It is why mood alleviation initiatives should be part of healthcare professional’s routine. As such, celebrating performance milestones not only encourages concerned employees but also refreshes others. Arranging and mandating weekly recreational activities can offer them necessary breathing space out of packed schedules. Similarly, offering off days can facilitate workers to focus on their well-being.\nMost importantly, attending to mood swings should also be self-driven. Even though refreshment may seem extravagant in attention-demanding professions, workers should utilize and relish their spare time. Thus chitchatting with colleagues during breaks on topics not relevant to the hospital can depart a soothing get-out from work-related stress.\nAdditionally, regular face-time with loved ones can be relieving and accomplishing. Nonetheless, providing healthcare workers with ways to uplift their mood is not merely an incentive but a necessity in a stressful work environment like the healthcare sector.\n5. Endorse and facilitate a self-care culture\nPrioritizing patients and their wellness are some of the fundamental professional and ethical obligations of healthcare professionals. When duty calls, they are ready to attend to patients 24/7. Sometimes, workers do not utilize necessary breaks or shorten them.\nHowever, work is not everything rather a part of one’s entire life. That is why individuals failing to create an equilibrium in work and personal matters drift towards several problems.\nThus healthcare setups should treat professionals’ healthcare on a priority basis. They should promote self-care and oversee its execution during lengthy and exhaustive work routines. Self-care is crucial to enable workers to continue providing effective services and better healthcare to their patients. Studies report an overwhelmingly 100% of the healthcare participants engaged in palliative care commended that self-care enabled them to provide better care to their patients. It means workers focusing on self-care are not only capable of delivering quality service but catering to personal healthcare effectively.\nConclusion\nThough the healthcare sector treats patient illnesses on a priority basis, employees’ health is equally crucial. Usually, healthcare workers also ignore hidden healthcare problems, which lead to further complications. As a consequence, mental health is becoming an issue of concern among healthcare professionals. Hence, early intervention and organizational assistance are crucial in preventing the effects of mental breakdown.", "pred_label": "__label__POS", "pred_score_pos": 0.9944808483123779} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis issue brief explores Elementary and Secondary School Emergency Relief Funds (ESSER) and how these funds can support summer and afterschool programs. It reviews amount of ESSER funds for each state, what the funds can be used for, and how programs can access these funds through grants and contracts. It also includes examples of how CT, GA, NH, UT, and WV are using the funds.\nThis webinar provided an overview of federal stimulus funding, specifically, the American Rescue Plan and the funding available to state and local education agencies, as well as $1.22 billion specified for summer as well as for afterschool. It also included speakers about the USDA meal program, Community Schools, and the American Camp Association on summer.\nThis webinar explores best practices in providing older youth with supportive and meaningful employment experiences and paid internships. The panel includes representatives from National Youth Employment Coalition, Summer Youth Employment Program from Charlotte, NC, College to Congress, and Community Relations Manager from Bank of America.\nThis webinar provides information to prepare summer staff to understand the overwhelming stress or trauma that youth may bring into a summer program.\nThe National Summer Learning Association has provided more than 40 webinars called the Voices of Summer Webinar Series. The webinars were held between spring 2019 and spring 2021. Presenters include national thought leaders, program providers offering promising practices, and researchers.\nThis week-long webinar series provides program leaders with tools they need to support children in summer during the pandemic and beyond. Speakers included national leaders from McKinsey, NWEA, Weikart Center, and AIR, as well as state and city examples.\nThese webinars feature thought leaders, researchers, journalists, and award-winning program leaders who share practices and research. November 16, 2020 included providers sharing promising practices during the pandemic. November 17 included journalists to explore how the election might shape the landscape and leaders who talked about legislation needed right now.\nThis report from National Summer Learning Association (NSLA) examines data from focus groups and interviews conducted with 21 leaders representing 15 national award-winning summer learning programs in September 2020 and data from a survey of 1,047 afterschool and summer providers conducted in partnership with Afterschool Alliance in July and August 2020.\nThe purpose of this playbook is to provide a long-term and sustainable framework for planning and executing evidence-based practices and partnerships for high-quality summer programs. It has a user-friendly design and includes sections on quality, safety, policies and funding, planning, and partnerships.\nThis virtual press conference brought together leading experts to explore summer solutions emerging in the pandemic. It begins with a review of the findings from the report by the National Academies of Sciences, Engineering, and Medicine on Shaping Summertime Experiences.", "pred_label": "__label__POS", "pred_score_pos": 0.8723366260528564} +{"content": "Chinese authorities have not abandoned blockchain technology despite the harsh crackdown on cryptocurrencies. Reports indicate Malaysian Bitcoin miners have been stealing energy to dig out digital gold. Cryptocurrencies in China have become non grata entities regardless of their associations.\nThe crackdown on cryptocurrencies is overwhelming much of the media space as market sentiment remains below the threshold of 25 on the Fear and Greed Index. The price of Bitcoin is descending without much volume and positive momentum to gather it back up. Cryptocurrencies exist because of blockchain, and while the interlink is rarely discussed, blockchain still holds intrinsic value for any entity or country vested in it. Expanding on the subject of crypto becomes more restrictive as countries that curbed crypto’s growth continue to enforce stricter rules.\nMalaysia Has No Love For “Dirty” Bitcoin\nIn a new video release, Malaysian police are reportedly crushing 1,069 ASIC miners using a steamroller. The market value of the digital-gold digging machines amounts to $1.25 million after authorities seized them during an electricity theft investigation.\nA Malaysian news outlet report indicates that the ASIC miners dispatched occurred in the city of Miri in the Malaysian province of Sarawak state. The seizure of 1,069 miners results from an electricity theft investigation between February and April 2021, where eight individuals were arrested. Furthermore, the report stated, “All seizures made in the cases that had been settled in court were disposed of.” As one Twitter user highlighted, ASIC miners could not have been repurposed because they do not have a GPU.\nThe March theft incurred electricity losses amounting to $2.2 million, with multiple reports stating the behavior was recurring in the country. According to Cambridge Bitcoin Electricity Map data, Malaysia accounts for 3.4% of the global hashrate as of April 2021. While digital assets are not legal tenders in Malaysia, cryptocurrencies are not illegal; however, they are unregulated.\nChina’s Clampdown\nChina’s disassociation with cryptocurrencies pushed most of the Chinese mining operations to Kazakhstan. According to a report, 90% of the total electricity produced is fossil-fueled. However, restrictions on mining and cryptocurrency transactions are not the only ways China is affecting crypto dispersion.\nReports highlight China has increased its control of cryptocurrencies, as Bishijie, a social network for discussing and distributing information about cryptocurrencies, has been forced to shut down. In addition, media reports emphasize that Bishijie or Coin World is already being investigated for issuing illegal digital assets in 2019.\nBishijie app was already removed from the app store, according to Jiemian News; however, the company is still updating BTC-related news. Moreover, with stricter rules towards cryptocurrencies, China aims to regain control of a sector that could imperil its political status by allowing digital anonymity to gather momentum.", "pred_label": "__label__POS", "pred_score_pos": 0.543911874294281} +{"content": "How to get an illegal Bitcoin transaction code\nHow to buy and sell illegal Bitcoins?\nRead more Bitcoin is one of the most popular and widely used digital currencies in the world.\nIt is also one of a few that does not require any central authority to verify the authenticity of transactions.\nBut the Bitcoin network is vulnerable to attack and it is possible for criminals to manipulate transactions, particularly by tricking users into paying with Bitcoin, or using fake addresses to make payments.\nThis week, a hacker called “Troy” leaked an unredacted copy of the Bitcoin transaction codes of more than 3,500 people, including hundreds of high-profile figures, including the US President.\nHe claimed to have cracked the code, but the information was not verified.\nWhat is the Bitcoin code?\nA Bitcoin transaction is a digital document that is created using the cryptographic algorithm known as “mining” or “mining”, and can only be completed by someone who holds a piece of software known as a “Bitcoin address”.\nIt is created in a software known to the bitcoin network as a software wallet, and has an amount of bitcoins held in a special “wallet address” that is kept in a server on a computer’s network.\nUsers can send money to each other using these addresses, but in order to make a payment, they must first confirm that the address is valid.\nThis is known as the “signature” of the transaction.\nThis signature is also known as its “coinbase” address.\nOnce a transaction is confirmed, the transaction can then be confirmed to be valid.\nFor example, if a person pays someone using an address known to be invalid, the person will not receive the money.\nIn the example above, the address “3D4YjZ7cjHgfj4YX1yCv5s6vf3d7jgYgqkxP3T2ZpBx” is known to have a valid signature.\nOnce the transaction is completed, a Bitcoin transaction has been recorded in the public ledger known as blockchains.\nBlockchains are publicly accessible, and are linked to each others Bitcoin addresses, and the public Bitcoin address that they are linked with.\nA transaction is “stored” in a Bitcoin wallet, which can be used to transfer the Bitcoin.\nA user’s Bitcoin address is stored in a wallet on their computer, which is then linked to the Bitcoin address in their Bitcoin wallet.\nWhen a user sends money from one Bitcoin address to another, the Bitcoin is sent to that address in the Bitcoin wallet in question.\nThis process is known in the jargon as “the Bitcoin network”.\nThe Bitcoin network processes the payments and records the transactions.\nTransactions can be confirmed and verified by the Bitcoin miners who are involved in creating the Bitcoin addresses.\nOnce verified, a transaction can be added to a block, or recorded in a block chain.\nA block chain is the most widely used method of linking a Bitcoin address with a block of transactions that has already been processed by the network.\nThe blocks can contain transactions from many different Bitcoin addresses and Bitcoin miners can check that all transactions are valid.\nHowever, there are also “miners” who only process transactions from the first 10 transactions on a block.\nThese miners can be found in the same Bitcoin network as the user they are mining for.\nA miner can also be a third party who performs additional computations to confirm transactions.\nThese are known as mining pools.\nThe mining pool can also send coins to a user’s wallet.\nFor instance, if someone sends money to a wallet with a valid Bitcoin address, the wallet can then send the funds to that wallet’s address.\nA wallet is the central hub where users and other users can deposit money to their accounts, pay bills, and buy or sell goods and services.\nThe wallet is also where users can send Bitcoin to another user.\nThis can happen using a service called a “cold wallet”, where a user holds a Bitcoin balance in a cold wallet account, which then allows a third-party to send Bitcoin directly to the wallet.\nThe same is true of Bitcoin transactions.\nUsers pay with Bitcoin in two ways: by sending the funds through a payment processor, and by using a website such as Coinbase.\nBoth of these are used for transferring funds to and from the Bitcoin ecosystem.\nBitcoin is not a currency, and is not regulated by any government.\nBitcoin has been around for a while, and Bitcoin mining has been used for many years by people in the mining industry.\nBut its adoption has skyrocketed in recent years, thanks to a combination of factors, including an increase in adoption by governments and a growing awareness of Bitcoin by businesses and the general public.\nAs a result, the use of Bitcoin is becoming increasingly mainstream, as it is used by companies such as banks, payment processors, and financial institutions.\nIn 2017, bitcoin prices fell by more than 30%, from about $1,800 to about $850 per coin.\nWhat should you do if you think you have been affected by a fraudulent Bitcoin", "pred_label": "__label__POS", "pred_score_pos": 0.5958607196807861} +{"content": "Malaffi recognised as a successful public-private data-sharing partnership model\n13 October 2021\nThe National Committee for Sustainable Development Goals recently launched a whitepaper\n“Accelerating achievement of the SDGs in the UAE: A blueprint for public-private data-sharing partnerships” as part of its efforts to accelerate the achievements of the United Nations’ Sustainable Development Goals in the UAE by highlighting the partnerships between public and private sectors in the field of statistical data exchange.\nDeveloped by the Federal Competitiveness and Statistics Centre, in cooperation with the UAE Private-Sector Advisory Council and Kearney, the report recognized Malaffi has a successful public-private data sharing partnership which helped address urgent COVID-19 problems.\nAccording to the United Nations’ official website on the SDGs, 90% of countries are still experiencing one or more disruptions to essential health services when reporting data under SDG 3 Health and Well-being. However, an integrated Health Information Exchange platform proved advantageous during the Covid-19 pandemic. Leveraging real-time public-private data integration through Malaffi helped the Department of Health – Abu Dhabi (DOH) to achieve a greater response to the pandemic.\nPlease find the white paper here.", "pred_label": "__label__POS", "pred_score_pos": 0.5672610402107239} +{"content": "Data Migration Risks\nThe world undoubtedly can no longer overlook the agility the cloud has provided businesses. It creates incredible opportunities for businesses to shift platform and continue everyday operations despite the ongoing battle with the global pandemic. Companies and corporations using the cloud aspire to increase agility, help employees centralise on business priorities, fuel top-line growth, drive downturn in capital expenses, and pay for only what you need on-demand. However, the type of migration instituted and infrastructure to support the process will determine exposure to risks and how much free time IT staff can allocate and invest in other projects.\nWhen and why is data migration difficult and risky?\nWhen data migration becomes a challenge, it tends to relate to data gravity which reveals how data attracts other data as it grows, how data integrates into a business, and how data becomes customised as time progresses. These factors attributing to data gravity disclose the difficulty of “disentangling” data as it migrates systems. Therefore, data must first simplify and overcome barriers of data gravity to evoke the advantages of migrating applications and data to a cloud infrastructure. Furthermore, it is crucial to allocate time at the initial stages of a project in sorting data and application complexities to improve data management, enabling application mobility and garner enhanced data governance.\nThe prominent issue arises when applications complicate data management by instituting new elements of application logic into the data management level, whereby each one is inapplicable to the following data use case. Consequently, the system will operate inefficiently and deprive TOS users of the capabilities to resolve bottlenecks or even facilitate decision-making. It is vital to evaluate system IT infrastructures and ask the respective software provider of their migration strategies and process to understand how they treat your data in each stage and if it benefits your operational needs.\nBusiness processes create outputs in their meaningful formats using data in isolation, which leaves integration for the next stage. As a result, application design, data architecture, and business processes must achieve cohesion and combine to envelop a harmonious environment. However, often, one of these groups are resistant or unable to change. Application administrators, consequently, omit ideal and straightforward workflows, resulting in subpar designs. Motioning a workaround that addresses these technical limitations immediately upon detection will prove beneficial though dismissing it in this stage will eventually resurface during data migration or integration projects. Overall, the software provider should encompass a robust system architecture to drive efficient data management, reinforcing a seamless data migration. Therefore, the application or system of choice must follow an explicit data structure while simultaneously achieving a harmonious environment.\nDespite the complexity, data migration grants operators and executives alike the strategic weapon that phases out their current operating legacy system. The terminal and organisation can then take progressive steps to achieve a complete cloud TOS infrastructure that advances ports and terminals in digitalisation and the industrial revolution 4.0.", "pred_label": "__label__POS", "pred_score_pos": 0.9679152965545654} +{"content": "Abstract\nIn a preregistered experiment, we examined the efficacy of arousal reappraisal as an intervention for reducing the negative effects of stress at retrieval on memory. Participants (\nN= 177) were semi-randomly assigned to one of three conditions: a Stress-intervention condition, a Stress-placebo condition, and a No-stress-placebo control condition. Participants viewed four images of complex, mildly negatively valenced scenes. One day later, they received an arousal reappraisal intervention or placebo before exposure to a laboratory stressor (or a control version for the No-stress condition). Participants were then tested on their memory of the images using a free recall instruction and multiple-choice recognition questions. As expected, negative affect and blood pressure increased for the stress conditions but not the control condition. Contrary to our hypotheses, memory performance did not statistically significant differ between the Stress-placebo condition and the No-stress-placebo control condition, indicating a lack of negative effects of acute retrieval stress on memory. Furthermore, we also found no statistically significant differences between the Stress-intervention condition and Stress-placebo condition in terms of memory performance, suggesting that the intervention did not assist with enhancing memory. We integrate interpretations of the findings from this study with a discussion of avenues for future research in this area.", "pred_label": "__label__POS", "pred_score_pos": 0.9984923601150513} +{"content": "Room: AAPM ePoster Library\nPurpose:\nStereotactic radiosurgery relies on very small field sizes on the order of a few millimeters to ablate lesions and spare normal structures. Although a 6 MV photon beam is most often utilized, there is an interest in lower photon energy beams for stereotactic radiosurgery due to their sharper dose fall off. This study provides a dosimetric comparison to determine if there is advantage of using 2.5 MV over 6 MV photons for stereotactic radiosurgery. Methods:\nThe Monte Carlo simulation codes BEAM/dosexyz were used to simulate 2.5 MV form a Varian TrueBeam and 6 MV beams from a Varian TX accelerator. The details of the incident beams including cone accessory were simulated, with calculated doses benchmarked against measurements. The dose calculations were based on a realistic treatment plan for thalamotomy treatment delivering over 145 Gy at isocenter using a 6 MV (4 mm cone) beam with 21 arcs. The calculations were repeated with a 2.5 MV beam with the same cone and delivery arcs. Results:\nFor a realistic patient treatment plan using 21 arcs with 4 mm cone beams delivered 15000 cGy, a significant dose reductions of 37% to brainstem and 50% to chiasm were obtained for 2.5 MV beams comparing to 6 MV beams. From the DVH analysis, the maximum doses to brainstem and Chiasm were 880.5 cGy (552.3 cGy) and 272.2 cGy (134.3 cGy) for 6 MV (2.5 MV) beams respectively. Conclusion:\nA significant reduced dose to organ-at-risks can be achieved by a 2.5 MV beam while providing same target dose. There is a clear dosimetric advantage of using 2.5 MV over 6 MV photons for stereotactic radiosurgery. The current 2.5 MV beam is for imaging and observed significant dosimetric benefit should encourage manufactures to develop lower energy photons for therapy treatment using LINAC-based radiosurgery system.\nNot Applicable / None Entered.\nNot Applicable / None Entered.", "pred_label": "__label__POS", "pred_score_pos": 0.8941798806190491} +{"content": "Nokia took the wraps off a new range of 5G microwave transport products for its Wavence portfolio, targeting communications service providers and enterprises with both indoor and outdoor options.\nOfferings include an outdoor nodal setup, featuring a networking interface module which can be plugged into an ultra-broadband transceiver (UBT) for either new deployments or to upgrade existing installations. The module is compatible with 80 GHz (E-band), twin and single UBTs, and supports “multiple directions, multiple interfaces and carrier aggregation.”\nThe vendor also unveiled two new Split Mount indoor units it claimed are the smallest on the market, and capable of withstanding extreme temperatures ranging from -40 to 65 degrees Celsius (-40 to 149 degrees Fahrenheit).\nAltogether, Nokia said its expanded portfolio is capable of covering use cases spanning short-haul, long-haul, E-Band and SDN to support 5G rollouts.\nMicrowave transport is traditionally used in areas where fiber is either physically or economically impractical, and is expected to continue to play a significant role in networks as 5G rollouts continue. In a report issued in October 2020, Ericsson forecast 38% of global backhaul connections would be based on microwave technology by 2025.\nData from Dell’Oro Group showed the microwave transmission market declined 6% in 2020, thanks in part to losses early in the year caused by the Covid-19 pandemic. Huawei held the highest market share, followed by Ericsson and Nokia. The latter had a particularly good Q3, outperforming the market alongside Aviat and Huawei, and increasing its E-Band market share 8 percentage points in the quarter.\nThe market research firm predicted the overall microwave segment would make a comeback in 2021, growing an estimated 4% to $3.1 billion.\nIn December 2020, Dell’Oro Group VP Jimmy Yu tipped demand for E-Band systems to accelerate and grow by more than 30% in 2021 “since 5G will require more backhaul capacity.” He added multi-band systems combining E-band and lower frequency links were also expected to become more popular, given these provide both increased capacity and resilience.\n“Therefore, we cannot help but think that the adoption of multi-band links will be more mainstream than niche in the coming year,” he wrote.", "pred_label": "__label__POS", "pred_score_pos": 0.5068913698196411} +{"content": "The downward trend in Australian school student scores in tests such as NAPLAN, PISA and TIMSS has understandably caused concern among Australian educators, policymakers and the media.\nThe push to remedy this trend is driving interest in pedagogies differing from the currently favoured, inquiry-based, child-centred educational practices. Numerous educational leaders and experts have proposed returning to guided instructional practices, or otherwise known as explicit teaching.\nAt Australian Christian College – Singleton, a six-year trial of explicit direct instruction (EDI) created a remarkable turnaround in NAPLAN results, enrolments and teacher engagement. Before exploring these aspects in more detail, it’s important to establish some background about EDI.\nExplicit Direct Instruction – A Brief History\nExplicit Direct Instruction evolved from Direct Instruction (DI), an approach developed in the mid-1960s by Siegfried Engelmann and colleagues at the University of Illinois at Champagne-Urbana.\nInitially shown to deliver far superior results across student total reading, total math, spelling and language when compared to nine other educational models, there is now a comprehensive, decades-long corpus of evidence confirming DI’s effectiveness. For example, Hattie’s 2009 synthesis of 800 meta-analyses found DI to be one of the most effective teaching strategies.\nWhy DI Works – Cognitive Load Theory\nDirect Instruction is predicated on behaviourist assumptions that all children can learn if they are taught well and the learning outcomes result directly from well-developed programs, competently implemented through the pedagogical process.\nIt is characterised by systematic, explicitly scripted lesson plans and curriculum materials designed to quickly lead students to mastery using sequentially delivered, small goal- and task-based learning components.\nThe lowercase use of “di” has evolved to denote approaches requiring teachers to develop lesson and resource material, whilst applying effective DI pedagogical practices.\nDI’s effectiveness has been linked to the cognitive load theory (CLT) developed by educational psychologist John Sweller in the 1980s. It emphasises reducing the cognitive load upon learners’ limited working memories, and identifying processes that enable transfer of knowledge from short-term to long-term memory to create retrievable blocks of knowledge (known as schemas).\nCLT posits that introducing short, scaffolded, simple-to-complex instructional chunks and worked examples facilitates transfer of new skills and concepts to long-term memory. It is best implemented by guided instruction practices, rather than discovery-based, problem-based, inquiry-based pedagogies.\nEDI Methods\nExplicit direct instruction is teacher-led and utilises strategies including:\nStarting lessons with a clear statement describing the learning objective. Teaching students the concepts and/or steps or processes used to execute the skills in that objective. Working problems with students at the same time while ensuring they execute each step correctly. Having students prove they have learned the concepts and skills before they are given independent practice.\nStrategies used to achieve these components include: frequently checking for understanding to verify students are learning; teaching by telling: using think-alouds to reveal the strategic thinking required to solve problems; and demonstrating using physical objects to clarify content and support kinaesthetic learning.\nEDI in Practice – ACC Singleton’s Transformation\nSingleton Christian College, in operation for over 30 years, became part of the Australian Christian College network in 2012. Before this, it had consistently registered literacy and numeracy levels significantly lower than national norms. The School was therefore approached by the Association of Independent Schools (AIS) NSW to participate in the Literacy and Numeracy Action Plan 2012-2016 – an initiative designed to assist schools struggling with poor literacy and numeracy.\nAfter examining evidence on literacy and numeracy improvement, the school implemented EDI in 2015, which proved key to the school’s academic recovery. Supporting EDI’s adoption\nShifting to EDI required a whole-school approach. Strategies used to achieve this included:\nTraining and mentoring of school leaders Staff training through dedicated EDI modules, school visits to observe effective EDI practice, provision of a key EDI text, and an intentional coaching program Professional instruction delivered by expert practitioners Purchasing of class resources aligned to the EDI approach.\nThe Results – a Remarkable Turnaround\nThese changes resulted in significant positive developments, including improved results on standardised academic tests, increased enrolments, positive parent feedback, enhanced teacher satisfaction, and recognition of teaching excellence from both the AIS and the University of Newcastle’s Education faculty.\nImproved academic performance\nNAPLAN test data show averaged scores for all domains lifted across all relevant primary year levels from 2013 to 2019:\nYear 3 – from 359 to 433 Year 5 – from 478 to 493\nSimilar NAPLAN results improvements have been achieved in the secondary years from 2014 to 2019:\nYear 7 – from 503 to 558 Year 9 – from 546 to 581\nSome domains evidenced standout improvements. For example, Year 3 average scores for reading jumped from 342 to 432, spelling from 357 to 446, and numeracy from 359 to 415.\nFor Year 5 scores, writing lifted from 412 to 470 and numeracy from 447 to 492. Between 2014 and 2019, Year 7 scores for reading increased from 500 to 549, grammar 525 to 582, and numeracy 496 to 588.\nThe adoption of a synthetic phonics program for Kindergarten students, taught using an EDI approach, also led to significantly improved Priority Literacy Skills.\nIn 2018, for example, students in term 1 tested with 33% foundational literacy skills, which by term 4 had increased to 82%. In 2020, students’ Priority Literacy Skills shifted from 52% in term 1 to 92.5% by end of year. These results confirm that the School’s literacy approach is succeeding.\nIncreased enrolments\nAt the beginning of the improvement process, ACC Singleton was a Kindergarten to Year 10 school with 50 students. It now caters for Kindergarten to Year 12 with over 200 students.\nThe changed teaching approach and resulting academic improvement correlates with a significant upturn in enrolments. Parent feedback surveys confirm the School’s focus on academic outcomes was the most significant enrolment driver.\nEnhanced teacher engagement\nACC Singleton has developed a comprehensive and supportive instructional coaching model with two key goals - to drive ongoing improvements in teacher performance and to support the timely and effective onboarding of new teachers.\nStaff members expressed satisfaction as they embraced the new pedagogy and worked explicit teaching into their classes. A survey asking what the School’s journey with EDI had been like personally and professionally elicited responses typified by the statement: “It has been a positive journey, well worth all of the hard work.”\nOne primary teacher expressed her appreciation saying, “I feel like I’ve been born again as a teacher.”\nTime for a change\nEDI’s merits have been borne out by decades of extensive research and the results of successful implementation in schools such as ACC Singleton. With its clear advantages over student-led, inquiry-based pedagogical approaches, it’s high time education faculties in western universities include this approach in teacher training.", "pred_label": "__label__POS", "pred_score_pos": 0.7966500520706177} +{"content": "NCASE Resource Library Reset Selections Topics Resource type Publisher Search Results Filter By\nThis comprehensive guide on preventing child abuse and neglect uses a strength-based framework and recognizes that there are actions we can take to address root causes and provide meaningful support. The guide provides information on resources and partners, and how to build protective systems and policies using a public health approach, acknowledging families' lived wisdom.\nThis report provides a synthesis of 76 high quality studies on the impact of COVID-19 on young children and early childhood education programs. The studies and accompanying evidence-based and equity-centered policy recommendations were created by 10 leading scholars and 10 leaders in policy and practice for early childhood.\nThis report summarizes survey data collected in 2020, both before and during the pandemic; it is the fourth survey, preceded by findings from 2004, 2009, 2014.\nThis toolkit includes resources that will help build child care supply. It includes six steps: (1) assess and plan; (2) identify resources; (3) generate awareness; (4) develop strategies; (5) implement your plan; and (6) evaluate and implement. The concepts build on recognized strategic planning principles and include stories of success. This resource supports the COVID-19 response.\nWith many school districts providing partial or full online learning, there is increased need for child care for working parents. This collection of online resources includes videos of providers, and identifies recommendations for new supports on funding, shared planning and decision-making, and technical supports. This resource supports the COVID-19 response.\nThese program standards, self-assessment rubric, and resources are designed to help afterschool programs evaluate and improve the support they are providing for youth who are engaged in distance learning.\nThe purpose of this playbook is to provide a long-term and sustainable framework for planning and executing evidence-based practices and partnerships for high-quality summer programs. It has a user-friendly design and includes sections on quality, safety, policies and funding, planning, and partnerships.\nThis report captures what was shared at an October 2019 Conference about the challenges of teaching social and emotional learning (SEL) in afterschool programs. It provides a brief history of the growing focus on SEL, along with a summary of remarks by national leaders.\nThe Collaborative for Academic, Social, and Emotional Learning (CASEL) collaborated with more than 40 partners to develop this SEL Roadmap designed to support teams in planning for the transition back to schools.\nThis guide provides engaging activities and challenges to be used for youth-serving summer programs, whether running virtually or in-person, or to send digitally to families. It is organized to support four different age groups (5-9), (10-12), (13-15), (16-18). The first unit was released May 27, 2020 and subsequent units will be released in two-week increments.", "pred_label": "__label__POS", "pred_score_pos": 0.6092852354049683} +{"content": "Place your order now for a similar assignment and have exceptional work written by our team of experts, At affordable rates\nFive factors are often mentioned as affecting a country’s accounting practices: (a) legal system, (b) taxation, (c) providers of financing, (d) inflation, and (e) political and economic ties.\nRequired: Consider your home country. Identify which of these factors has had the strongest influence on the development of accounting in your country. Provide specific examples to support your position.", "pred_label": "__label__POS", "pred_score_pos": 0.9972661137580872} +{"content": "Nature, Vol.587, No.7832, 139-+, 2020\nThe landscape of RNA Pol II binding reveals a stepwise transition during ZGA\nZygotic genome activation (ZGA) is the first transcription event in life(1). However, it is unclear how RNA polymerase is engaged in initiating ZGA in mammals. Here, by developing small-scale Tn5-assisted chromatin cleavage with sequencing (Stacc-seq), we investigated the landscapes of RNA polymerase II (Pol II) binding in mouse embryos. We found that Pol II undergoes 'loading', 'pre-configuration', and 'production' during the transition from minor ZGA to major ZGA. After fertilization, Pol II is preferentially loaded to CG-rich promoters and accessible distal regions in one-cell embryos (loading), in part shaped by the inherited parental epigenome. Pol II then initiates relocation to future gene targets before genome activation (pre-configuration), where it later engages in full transcription elongation upon major ZGA (production). Pol II also maintains low poising at inactive promoters after major ZGA until the blastocyst stage, coinciding with the loss of promoter epigenetic silencing factors. Notably, inhibition of minor ZGA impairs the Pol II pre-configuration and embryonic development, accompanied by aberrant retention of Pol II and ectopic expression of one-cell targets upon major ZGA. Hence, stepwise transition of Pol II occurs when mammalian life begins, and minor ZGA has a key role in the pre-configuration of transcription machinery and chromatin for genome activation. Binding of RNA polymerase II during zygotic genome activation in mouse embryos is determined using the newly developed method Stacc-seq.", "pred_label": "__label__POS", "pred_score_pos": 0.9803224802017212} +{"content": "North American Wetlands Conservation Act (NAWCA) grants increase bird populations and wetland habitat, while supporting local economies and American traditions such as hunting, fishing, bird watching, family farming, and cattle ranching. Wetlands protected by NAWCA provide valuable benefits such as flood control, reducing coastal erosion, improving water and air quality, and recharging ground water.\nThe NAWCA program provides matching grants to wetlands conservation projects in the United States, Canada, and Mexico. There is a Standard and a Small Grants Program. Both are competitive grants programs and require that grant requests be matched by partner contributions at no less than a 1-to-1 ratio.", "pred_label": "__label__POS", "pred_score_pos": 0.6591067314147949} +{"content": "The origins of digital storytelling are seen to be the pioneering work led by Dana Atchley and Joe Lambert in California in the 1990s (Hartley & McWilliam, 2009). The emergence of digital storytelling at this time was a reflection of the increasing accessibility of digital technologies and a cultural shift toward the consumer as producer that has continued further with Web2.0 technologies. The innovation led by Atchley was to ‘develop an exportable workshop-based approach to teach “ordinary” people ... how to produce their own personal videos’ (Hartley & McWilliam, 2009: 3).\nHartley & McWilliam (2009:4-5) argue that at this moment in time digital storytelling provides a pivotal term that can be used to represent:\nAn emergent form, combining the personal narrative and documentary A new media practice, combining individual tuition with new publishing devices An activist/community movement, combining experts with consumer led activity A textual system, challenging the traditional view of the producer/consumer model and new forms of literacy.\nA typical digital story created within this tradition is a personal narrative of no more than 2-3 minutes. Burgess & Klaebe (2009: 155) identify two important core elements in the wide range of practice that has evolved in this tradition: the collaborative workshop and the first-person narrative. The workshop element, whereby support can be provided for the crafting of stories, contrasts digital stories created in this tradition with the more informal ‘stories’ that are being made available through Web2.0 platforms such as YouTube. These creations are less ‘top-down’ in approach and highlight a criticism of the CDS model that it can be too ‘teacher-centric’ (Hartley & McWilliam, 2009: 15). This CDS approach, while using simple technologies, has also been critcised for being 'deceptively complicated' because of the formalised workshop approach (Dush, 2009: 261). This will present barriers to use, particularly in educational settings, and make it difficult to sustain as a practice. The focus on the personal narrative also represents a potentially restrictive view for educational use, and Hartley & McWilliam (2009: 15) note that the emphasis on self-expression can lead to a ‘serious’ work being underdeveloped. Other developers of digital stories have expanded the range of uses and the definition of digital storytelling; for example, the website 'Educational Uses of Digital Storytelling', developed at the University of Houston, organises stories into three categories:\nPersonal narratives Stories that inform or instruct Stories that examine historical events.\nThe CDS tradition of digital storytelling has informed and inspired a wide range of activities in different contexts. The workshop dynamic, as illustrated through the Capture Wales project (Meadows & Kidd, 2009: 106), lies at the core of why this approach has gone on to be used within community projects, health work and professional development. The workshop can have a theapeutic benefit, helping to create a coherent story of events which have personal value to the individuals involved. For example:\nPatient Voices Project: project to gather the stories of ordinary people to inform health care professionals\nKelvin Grove Urban Village: digital stories representing the indigenous, military, educational, residential and natural history of this Brisbane urban development.\nWithin education it is increasingly used within schools, particularly for engagement and literacy development, though the nature of digital storytelling does mean that the focus of use will vary by age. Within higher education digital storytelling is most common within education departments, reflecting the use in schools, and also in media production departments (McWilliam, 2009: 46). This pattern of usage does reflect the CDS tradition. The potential applications increase if a broader interpretation of digital storytelling is adopted, such as new media narrative. This wider pattern of usage has been evidenced at the University of Gloucestershire with use for a variety of purposes across a range of disciplines (Gravestock & Jenkins, 2009; Jenkins & Lonsdale, 2008).", "pred_label": "__label__POS", "pred_score_pos": 0.7880141735076904} +{"content": "Dorri Partain Contributor The United States Congress was setting aside lands for national parks years before they had created a department to oversee those lands. Yellowstone, the first national park, dates to 1872 but the National Park Service wasn’t officially created by act of Congress until August 25, 1916. Operating under the Department of the Interior, the National Park Service has grown to manage 418 federal sites, including parks, monuments, memorials, military parks, historic sites, recreation areas, seashores, scenic riverways and scenic trails. Collecting fees to enhance national park lands for the comfort of visitors began with the Land and Water Conservation Fund Act in 1908. The act has been updated nearly every decade since, with the Fund Act of 1965 stating, “Clear notice that a fee or charge has been established shall be posted at each area to which it is applicable” and “that no free passes shall be issued to any member of Congress or other government official.” The Federal Lands Recreation Enhancement Act of 2004 stipulates that 75% of fees collected for entrance, camping, and other permits shall be used for park maintenance and programs, with current entrance fees set at $25.00 per day for one vehicle and passengers, $15.00 for visitors arriving on foot or bicycle, and $25.00 for each motorcycle. Entrance fees are waived on six days each year: Martin Luther King Jr. Day, the Great American Outdoors Act Anniversary (August 4), the National Park Service Birthday (August 25), National Public Lands Day (September 25), Veteran’s Day and the first day of National Park Week. The Short-Term Entrance Permit for Rocky Mountain National Park shown here was issued July 23, 1968. Based on the entrance code, the entrance fee was $1.00 for one vehicle with passengers. The fee also included entrance to the Shadow Mountain National Recreation Area, located at the southwestern border just outside the national park.", "pred_label": "__label__POS", "pred_score_pos": 0.7529469728469849} +{"content": "Changing the expectations of delivery, drone delivery company Wing has been operating in select locations in Australia and across the world.\nAn average delivery time of 10 minutes due to the impressive speed and agility of the drones is set to transform how we view delivery services.\nAs a consumer this sounds like a dream- no longer waiting days for your items or sitting hungry for an hour until dinner arrives, but what does this mean for the skies above our towns or cities and what will happen to those who already work in delivery services?\nDelivery drones would mean an entire transformation of law and legislation to regulate airspace, leading to the privatization of an entire space which has been mostly unused. Drones continue to become more available faster than the laws that govern them are created. Across the world drones have led to issues surrounding damages caused by malfunctions or conflicts when drones are shot down by landowners. Scenarios that cause legislation to clash, creating a grey area of the unknown.\nThe commercial applications of drones raise several considerations surrounding monitoring and controlling them as well as remaining aware of weather conditions in specific areas. Advanced monitoring technology and autonomous systems make the drones not directly piloted by a person. While it removes the need for direct delivery drivers, drones create a new style of workforce required to ensure the technical systems function correctly.\nWith over 100 000 delivers made globally, Wing has seen a positive reaction from consumers. There are many questions surrounding the overall impact on the industry and society, following the issues at Amazon warehouses. As delivery times reduce, pressure from the competition could lead to workers being put under strain.\nWhile there are many concerns and questions surrounding Wing and their delivery drones, excitement about swift and contactless delivery continues to grow, and the nature of transport continues to evolve.", "pred_label": "__label__POS", "pred_score_pos": 0.6254627704620361} +{"content": "In this Section\n198943 Effectiveness of disaster surge training for public health nurses\nTuesday, November 10, 2009: 3:30 PM\nBackground: Due to current expectations of public health nurses (PHNs), competency based training for surge capacity is a critical need. This evaluation assessed the effectiveness of a blended educational intervention (in-class and online learning) developed to enhance Ohio PHNs self-perceived competencies regarding confidence and need for training in 25 previously validated PHN disaster surge competencies. The educational intervention, developed using adult learning principles, addressed the role and skills of PHNs in preparedness, response, and recovery related to public health surge events.\nMethods: A pre-intervention survey was given during each of the in-class seminars (N=182) to determine self-perceived confidence and need for further training prior to the competency building intervention. Post-intervention surveys were mailed to all participants who had completed the in-class seminar and at least portions of the online surge curriculum. Using paired t-tests, pre- and post-survey results were compared (N=54).\nResults: PHNs confidence in performing all 25 nursing competencies significantly increased and their self-perceived need for further training correspondingly significantly decreased. Subgroup differences at post-test indicated directors of nursing (n=19) self-perceived competence in describing crisis, crisis management, emergency, disaster, catastrophe, and surge was significantly greater than public health nurses (n=22). Those completing all components of the blended educational intervention had greater self-perceived confidence in their ability to locate their health department's disaster plan resources and their ability to describe the PHN functional roles in the plan.\nConclusions: Using a blended learning approach to surge training effectively improved confidence in competencies for PHNs and reduced the participants' perceived need for further training.\nPresenting author's disclosure statement:\nI agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.", "pred_label": "__label__POS", "pred_score_pos": 0.9784997701644897} +{"content": "We assess several key measures of tobacco use among underage individuals, including awareness of tobacco products, current and ever tobacco use, demographic characteristics, brand and flavors used, and sources of access. The annual target sample size for the survey is 5,000 individuals under the legal age for tobacco use. We met our target from May to November 2020, collecting data from 5,252 underage individuals. We shared this data with FDA and made the results public through our Altria Science website, where we provide updates every 6 months.\nThis Underage Tobacco Use Survey is designed to help us meet stakeholder expectations – made clear through interactions with FDA personnel evaluating product and claim authorizations, the Tobacco Product Scientific Advisory Committee, investors, public health groups and others – that we and other tobacco manufacturers need to understand the latest product-specific underage tobacco use trends.", "pred_label": "__label__POS", "pred_score_pos": 0.9941077828407288} +{"content": "Cement Q2 Earnings Preview - Double Whammy Of High Cost, Softened Prices To Weigh On Margins: KRChoksey BQ Blue’s special research section collates quality and in-depth equity and economy research reports from across India’s top brokerages, asset managers and research agencies. These reports offer BloombergQuint’s subscribers an opportunity to expand their understanding of companies, sectors and the economy.\nKRChoksey Research Report\nWe expect the cement companies to remain resilient during the quarter, despite the confluence of negative factors such as seasonality, sand availability issue, and rising input cost, weighing on the sector.\nTraditionally, Q2 has been a muted quarter, but Q2 will be relatively stable in the current fiscal due to the lower base and improving demand environment.\nOverall, for Q2 FY22E, our cement coverage universe is expected to report sales growth of 8.4% YoY, and Ebitda will decline by 3.6% YoY.\nOn a sequential basis, most of the companies under our coverage are expected to report a de-growth, except for The Ramco Cements Ltd. which is expected to report a sales growth of ~14% mainly due to lower base.\nThe cumulative realisation for our coverage companies is expected to grow by ~4% YoY.\nClick on the attachment to read the full report: DISCLAIMER This report is authored by an external party. BloombergQuint does not vouch for the accuracy of its contents nor is responsible for them in any way. The contents of this section do not constitute investment advice. For that you must always consult an expert based on your individual needs. The views expressed in the report are that of the author entity and do not represent the views of BloombergQuint. Users have no license to copy, modify, or distribute the content without permission of the Original Owner.", "pred_label": "__label__POS", "pred_score_pos": 0.8047053813934326} +{"content": "Biofuels and the need for additional carbon\nUse of biofuels does not reduce emissions from energy combustion but may offset emissions by increasing plant growth or by reducing plant residue or other non-energy emissions. To do so, biofuel production must generate and use ‘additional carbon’, which means carbon that plants would not otherwise absorb or that would be emitted to the atmosphere anyway. When biofuels cause no direct land use change, they use crops that would grow regardless of biofuels so they do not directly absorb additional carbon. All potential greenhouse gas reductions from such biofuels, as well as many potential emission increases, result from indirect effects, including reduced crop consumption, price-induced yield gains and land conversion.\nIf lifecycle analyses ignore indirect effects of biofuels, they therefore cannot properly find greenhouse gas reductions. Uncertainties in estimating indirect emission reductions and increases are largely symmetrical. The failure to distinguish ‘additional’ carbon from carbon already absorbed or withheld from the atmosphere also leads to large overestimates of global bioenergy potential. Reasonable confidence in greenhouse gas reductions requires a precautionary approach to estimating indirect effects that does not rely on any single model. Reductions can be more directly assured, and other adverse indirect effects avoided, by focusing on biofuels from directly additional carbon.", "pred_label": "__label__POS", "pred_score_pos": 0.8201808929443359} +{"content": "Judicial integrity, one of the pillars upon which rule of law rests, depends on a long list of factors which continues to be adapted in a fast-changing world. While national contexts vary, judiciaries often face comparable challenges in ensuring independence and integrity in their respective countries, and they agree on the need to ensure that guidelines on judicial matters remain current.\nWhile the basics of judicial integrity have been agreed and enumerated in the Bangalore Principles of Judicial Conduct, the guidelines on some topical matters may not be up to the required standards. To overcome this, two big meetings were held in Seoul in December, the first organized by the Judicial Policy Research Institute of the Supreme Court of the Republic of Korea; the second, by UNODC.\nSextortion, as defined by the International Association of Women Judges (IAWJ), is the abuse of power to obtain a sexual benefit or advantage. As such, it is a form of corruption in which sex, rather than money, is the currency of the bribe. It is not limited to certain countries or sectors and can be found wherever those entrusted with power lack integrity and try to sexually exploit those who are vulnerable and dependent on their power.\nThe IAWJ has succinctly explained the principle underlying sextortion as follows: what distinguishes sextortion from other types of sexually abusive conduct is that it has both a sexual component and a corruption component. The sexual component of sextortion arises from a request - whether implicit or explicit - to engage in any kind of unwanted sexual activity, ranging from sexual intercourse to exposing private body parts.\nWhile the pace of developments in technology continues to accelerate to the great pleasure of many, it does present challenges to certain categories of professional disciplines whose nature does not lend itself well to much flexibility; with the preservation of judicial integrity at the helm of their principles, many judges may have difficulty embracing rapid innovation.\nJudges must comply with legal and ethical ramifications which other professions may not face when using technology. This is particularly the case when considering social media platforms, which have become ubiquitous in the last few years; inserting themselves into people's mundane activities, they allow instant communication with family, friends and total strangers, the sharing of holiday photos and funny memes, and the ability of commenting on news stories.\nThe effectiveness of any judiciary depends upon its perceived legitimacy, especially in the eyes of the public. This perception requires not only that the judges uphold the highest standards of integrity and independence, but also that states respect judicial independence and do not undermine judicial decisions.\nA successful judiciary is one whose members are appointed following a rigorous process assessing both the candidate's legal qualifications as well as integrity. Different countries' constitutions and other laws provide for different requirements, but it is crucial that only the best people are appointed to judicial positions. Judiciaries should not be politicized - this means that ruling parties should not appoint judges who will be answerable to them and not to the constitution and members of the public.\nEstablished in 2016, the International Anti-Corruption Excellence Award is designed to showcase creative and outstanding achievements of anti-corruption projects from across the globe and publicly acknowledge these exceptional efforts.\nAwarded by the Rule Of Law and Anti-Corruption Center (ROLACC), and presented in support of the anti-corruption mandate of UNODC, the initiative promotes the importance of tackling corruption and encourages the implementation of the United Nations Convention against Corruption.", "pred_label": "__label__POS", "pred_score_pos": 0.5654458403587341} +{"content": "A shortage of crypto expertise is driving up salaries in Indian firms involved in the domestic and worldwide blockchain industries, according to local media, citing data from recent research. In the last year, there has been a significant increase in the need for specialists in the sector. Crypto experience may earn you up to $100,000 per year.\nIndian IT organizations offering services to worldwide customers, fintech startups, and consulting firms have been fighting for professionals with experience in crypto technology, resulting in a wage war, according to the Economic Times. According to a business daily study, demand for this sort of expertise has grown considerably in recent months.\nAccording to the publication, the number of current job vacancies this month is over 12,000, representing a 50% rise over last year. The figures cited are from the most recent report from recruiting firm Xpheno.\nThe relatively young age of bitcoin technology, which is just a little more than a decade old, is likely the major cause for the disparity between the restricted number of specialists in the area and the open vacancies. The sector’s pay is being pushed up by a talent shortage.\nAccording to the report, salaries for professionals with eight to ten years of expertise may reach up to 80 lakh Indian rupees per year, which is more than $106,000 at the time of writing. Xpheno co-founder Kamal Karanth commented on the findings:\nDespite the 12-year life of the crypto domain, its mainstream visibility and talent-related attention is under a decade.\nAnother study, conducted by the Indian IT industry group Nasscom and cryptocurrency exchange Wazirx, found that the country’s crypto-tech business employs around 50,000 people. Nasscom senior vice president Sangeeta Gupta told the Economic Times that if the industry continues to develop at its present rate, the group anticipates 30 percent more employment to be generated in the coming months.\nCompanies in the field frequently seek candidates with blockchain, machine learning, security solutions, Ripplex solutions, data analysis, and front and back-end capabilities. According to Xpheno, there is a 30 to 60% talent supply deficit in certain high-demand skill categories.\nHowever, for some specialized talents in cryptography, cybersecurity, data analytics, and other fields, the gap has already reached 50 to 70%. According to Kamal Karanth, the struggle for talent and the existing wage war would continue for the next two years.\nPatrick.", "pred_label": "__label__POS", "pred_score_pos": 0.6886988878250122} +{"content": "Sustainability is the philosophy and practice of using resources in a manner that will preserve their supply perpetually into the future. It prioritizes the inherent value of complex and delicate environmental systems while recognizing the human need for consumable products, as well as more abstract economic and political considerations. Advocates of sustainability promote regulations, protections, and behavior shifts on a large social scale, as well as individual habits that reduce our detrimental impact on our surroundings, aiming for a balanced relationship between ourselves and our world.\nWe’ve started gathering valuable information on this topic, but haven’t yet curated the findings.\nThe Great Turning identifies the shift from a self-destroying political economy to one in harmony with Earth and enduring for the future. It unites and includes all the actions being taken to honor and preserve life on Earth. It is the essential adventure of our time.", "pred_label": "__label__POS", "pred_score_pos": 0.5329971313476562} +{"content": "One of the most chilling stories in the natural world, seemingly only in the imagination, has obvious evidence. It is the story of an eel stabbing the neck of a heron despite being swallowed by a predator.\nThe images were taken by Sam Davis in Ireland. Initially, he saw a heron in flight with a strange object hanging below its neck. He guessed that the bird was bitten on the neck by a snake or some other species and refused to let go.\nThe heron is flying with a strange object in the neck that makes many people curious\nHowever, when he approached and photographed at a closer angle, he saw that the eel had pierced the neck of the cephalopod. Apparently, it was swallowed by the heron and used its sharp tail to tear the flesh of the predator to get out.\nThe scene looks like something out of a horror movie, but it’s not without foundation. The heron is the eel’s number one enemy, but if it swallows its prey alive, it’s unknown what will happen.\nEels with pointed tails often stab the stomach or body of a predator to find a way to escape. However, the time it got stuck in the escape process while the heron did not die, it became the target of both eagles and foxes.\nPerhaps, an inevitable sad ending due to the not-so-light wound and the stalking of predators.", "pred_label": "__label__POS", "pred_score_pos": 0.5595227479934692} +{"content": "ABSTRACT\nComputational tools for integrative analyses of diverse single-cell experiments are facing formidable new challenges including dramatic increases in data scale, sample heterogeneity, and the need to informatively cross-reference new data with foundational datasets. Here, we present SCALEX, a deep-learning method that integrates single-cell data by projecting cells into a batch-invariant, common cell-embedding space in a truly online manner (\ni.e., without retraining the model). SCALEX substantially outperforms online iNMF and other state-of-the-art non-online integration methods on benchmark single-cell datasets of diverse modalities, (e.g., scRNA-seq, scATAC-seq), especially for datasets with partial overlaps, accurately aligning similar cell populations while retaining true biological differences. We showcase SCALEX’s advantages by constructing continuously expandable single-cell atlases for human, mouse, and COVID-19 patients, each assembled from diverse data sources and growing with every new data. The online data integration capacity and superior performance makes SCALEX particularly appropriate for large-scale single-cell applications to build-upon previously hard-won scientific insights. Competing Interest Statement\nThe authors have declared no competing interest.\nFootnotes\n↵5 Co-first authorship", "pred_label": "__label__POS", "pred_score_pos": 0.9670259952545166} +{"content": "In this webinar, Equitable Origin shares the insights gained and outputs generated from a ten month project funded by the ISEAL Innovations Fund to explore how FPIC processes could be better monitored and verified. The right to free, prior and informed consent (FPIC) is a key principle of international human rights law.\nThis desk research is an output from the Delta Framework, an ISEAL Innovations Fund supported project that is developing a cross-commodity framework for sustainability monitoring and reporting.\nThis report presents methodology and results of the ISEAL Innovations Fund-supported project 'Codifying Free, Prior and Informed Consent (FPIC) in Voluntary Standards Systems', led by Equitable Origin", "pred_label": "__label__POS", "pred_score_pos": 0.9788732528686523} +{"content": "Chapter\nChapter\nPlasticity across Generations\nDOI link for Plasticity across Generations\nPlasticity across Generations book\nABSTRACT\nPlasticity is the ability of an individual organism or genotype to respond to environmental conditions, such that a given environmental state consistently induces a particular phenotype. Plastic responses are often associated with epigenetic modifications that mediate changes in gene expression and can have profound effects on fitness. While plasticity during the individual lifetime has been recognized for a long time, it is now clear that many environmental factors can induce epigenetic, physiological, or behavioral changes that have consistent effects on offspring development, and that some of these effects can persist for multiple generations. Such ‘transgenerational plasticity’ is a form of nongenetic inheritance, and studies on diverse organisms show that a broad range of environmental factors can induce transgenerational plasticity in physiological, behavioral, morphological, and life-history traits. This chapter considers the fitness effects of transgenerational plasticity and its potential to play a role in adaptive evolution. While some instances of transgenerational plasticity have clearly evolved as facultative, fitness-enhancing strategies, many examples of transgenerational plasticity are more plausibly interpreted as non-adaptive effects of stress or pathology. This chapter argues that considerable caution should be exercised in inferring adaptive function for observed transgenerational plasticity effects. Nonetheless, both adaptive and non-adaptive forms of transgenerational plasticity could contribute to adaptive evolution. Many questions and controversies remain to be resolved about the phenotypic scope, fitness consequences, mechanisms, and evolutionary causes and consequences of transgenerational plasticity.", "pred_label": "__label__POS", "pred_score_pos": 0.9211385846138} +{"content": "A healthy workflow is an essential element of success for every professional team. However, problems begin to arise when a project manager has to orchestrate a consistent flow within a virtual environment.\nThe modern shift to a remote-heavy work model has put a novel kind of pressure on teams as they strive to stay on the same page. Flexible schedules and different time zones can make it difficult to be on the clock at the same time — let alone to collaborate together.\nHere are a few suggestions for simple yet effective ways to overcome those growing pains and reconcile your team’s workflow.\n1. Create Crystal Clear Agendas\nMeeting agendas aren’t a perfunctory step of a professional gathering. They’re an art form that, when done well, can revolutionize the productivity of a meeting. Agendas provide purpose, set expectations, empower individuals, and enhance focus.\nA good meeting agenda should include the topics being addressed as well as action items, talking points, and other activities. These should be outlined, with each task assigned and meeting objectives unequivocally stated.\nThe meeting organizer owns the agenda, but it’s absolutely critical to provide the agenda to the entire team before the meeting. By doing this, you ensure that, whenever your team is assembled for a few moments, everyone comes prepared and informed.\n2. Embrace Asynchronous Meetings\nWhen you think of a meeting, it evokes images of well-dressed employees gathered around conference tables in the same space. It’s time to throw that idea away.\nInstead, try using an asynchronous meeting approach. This is a kind of meeting where communication doesn’t happen in real-time and also doesn’t require an immediate response. By sending out a pre-recorded video of the meeting, it allows meetings to take place without the need to align schedules.\nAn asynchronous meeting can be as simple as an email exchange or communication via some other messaging application that doesn’t require real-time attendance. However, that doesn’t mean you let the conversation run wild.\nTo hold a real asynchronous meeting, you must provide a sense of structure. Meeting organizers must select a limited number of participants and create an agenda with a clear purpose. As the meeting “takes place,” they must also set clear deadlines, invoke responses, and generally oversee the progress of the event.\n3. Set Up a Centralized, Cloud-Based Workflow\nIt’s easy to attack the inefficiencies of meetings, especially in an online format. However, the truth is, meetings do offer a sense of structure and forward momentum for a team.\nOne of the best ways to maintain this progress with a multi-time zone workforce is by setting up a centralized, cloud-based workflow space for your team’s activities. This isn’t just referencing a cloud data storage solution like Google Drive or DropBox. It can require a full-blown workflow application.\nA good workflow app doesn’t just offer universal access to critical team information. It also helps shepherd your team through its activities through things such as setting deadlines and assigning responsibilities. It also provides a central, organized space where your team can upload shared documentation from various third-party applications.\nThe remote work world has a plethora of benefits. But that doesn’t change the fact that it has thrown a monkey wrench into the workflow factor for a lot of companies.\nThe good news is that there are alternatives that can ameliorate the issue. If you’re willing to embrace things like clear agendas, asynchronous meetings, and workflow apps, you can eliminate the bulk of the need for regular meetings — and not shed an ounce of productivity in the process.", "pred_label": "__label__POS", "pred_score_pos": 0.6615660190582275} +{"content": "Abstract\nDesign teams commonly form quantitative functional specification lists that define performance targets for a product. Meeting these specifications ensures that the customer needs are satisfied. A central difficulty is to identify the relevant metrics to use as specifications. A working methodology is presented here to establish relevant, quantitative, measurable performance specifications. To start, customer needs, their importances, and the customer use patterns are gathered for the product. Voice-of-the-customer methods are augmented to distinguish no-compromise constraints that must be met. Next, a design is analyzed to establish a representative function structure, applying Pahl and Beitz’s systematic design approach. An optimal function structure can now be defined by a condition of simultaneous maximum simplicity and comprehensive coverage of the gathered customer needs. The function structure can then be used as a list over which specifications are to be made, with at least one specification per sub-function. Having a rational function structure allows a team to more easily determine variables on which to make specifications. A team can then use the House of Quality to document and form consensus over these specifications in the typical way.", "pred_label": "__label__POS", "pred_score_pos": 0.5379244089126587} +{"content": "Ellen is an ESRC-funded PhD student in the Centre for Language and Communication Research at Cardiff University. For her doctoral project, Ellen has designed a vocabulary development programme, which explores whether explicit teaching of word parts, word history and vocabulary decoding skill could influence pupils’ ability to comprehend complex academic vocabulary at the transition from primary to secondary school. Her research also investigates the social factors which may influence pupil vocabulary development. Overall, her work aims to understand strategies that could be used to address the ‘word gap’—where children have a vocabulary below age-related expectations—and inform English language pedagogical practice in the future.\nAlongside her research, Ellen works as tutor on Cardiff University’s English language degree programme and as a writing support tutor for the School of English, Communication and Philosophy. Ellen is committed to supporting young people from all backgrounds access new educational experiences and build confidence in their skillsets. She works as a tutor and mentor for four educational charities: the English Speaking Union, the Brilliant Club, Cardiff University’s ‘Step Up to University’, and Wales’ Seren Award. She supports these charities by delivering subject specific and skills-based masterclasses, offering one-to-one academic and career development support, and facilitating literacy and oracy workshops that aim to help young people develop the communication skills they need to thrive.\nEllen has also worked as an Education Policy Research Intern for the Welsh Government. She wrote two evidence-based reviews that informed the National Strategy for Education Research and Enquiry in Wales.", "pred_label": "__label__POS", "pred_score_pos": 0.8954995274543762} +{"content": "spotlight on electric vehicle infrastructure\nPublic car-charging infrastructure is a key part of the UK Government’s recently announced Green Industrial Revolution, which includes £950 million to support the roll-out of rapid EV charging hubs at every service station on England’s motorways and major A-roads, as well as £90 million to fund local EV charging infrastructure to support the roll out of larger on-street charging schemes.\nWith charging capacity a concern for potential EV buyers, the challenge for network and infrastructure providers lies in differentiating their brands, scaling up their networks, and building a base of satisfied users.\nDownload our spotlight below to learn how EV marketers can address a diverse range of decision makers, influencers and users.", "pred_label": "__label__POS", "pred_score_pos": 0.6192361116409302} +{"content": "Raptor Project\nRAPTOR PROJECT\nINTRODUCTION\nTo align with IGO’s strategic focus on clean energy metals, IGO prioritises the exploration of terranes prospective for polymetallic magmatic nickel sulphide and sediment hosted copper deposits.\nThe Company has acquired exploration access to extensive belt-scale land positions across Australia and in Greenland, and all are highly prospective for multiple large base and precious metals discoveries (Figure 1).\nFigure 1 – Location Map of IGO’s Belt-scale Exploration Projects and Operations\nThe Raptor Project is a belt-scale Proterozoic magmatic nickel-copper sulphide project, which has had very little modern exploration. The project has similar geology to IGO’s Fraser Range and Kimberley projects. Raptor complements the long-term outlook of IGO’s Ni exploration portfolio as a less mature, but highly prospective 100%-owned landholding covering 17,161km\n2.\nTECHNICAL OVERVIEW\nRaptor is a first-mover, belt-scale project where IGO is targeting the coincidence of a continent scale paleo craton margin and a regional scale gravity ridge anomaly (“Willowra Gravity Ridge”) in the Aileron Province (Figure 2). This geological feature is similar in scale to the Fraser Zone of the Albany Fraser Orogen and the Halls Creek and King Leopold Orogens in the East and West Kimberley, respectively. Access to the opportunity has been secured through open staking on a 100% IGO-owned basis.\nPrevious work in the area has only focused on gold exploration. Extensive vacuum and rotary air blast (RAB) drilling had been completed by previous explorers, but most of the samples collected were only assayed for gold and arsenic. IGO’s review of Northern Territory government open file data reports found one company that analysed for a broader suite of elements in the mid-1990’s and identified mafic and ultramafic rocks in the area. That company reported an intercept of 4m grading 1.35% Ni and 0.21% Cu from 39m in a metagabbro at the Osprey Target, and 28m grading 0.32% Ni and 0.31% Cu from 20m at the Kestrel Target in an “amphibolite”[1]. These results may be akin to the first discovery of nickel and copper at the Talbot Prospect in the Fraser Range during the early 1970’s, demonstrating that the processes required to potentially form world-class magmatic nickel-copper mineralisation has occurred in the terrane.\nOn-ground exploration by IGO is yet to commence due to the need to secure agreements with traditional owner groups prior to the granting of tenements. An on-country meeting was recently held and IGO is working with the Central Land Council to finalise a deed for exploration that will cover the entire Project.\nIGO has proactively collected airborne geophysical data across the entire belt through collaborative funding programs with the Northern Territory Geological Survey as part of their Resourcing the Territory initiative. The entire project area is now covered by 100m-spaced lines of aeromagnetic and radiometric data, and co-funding has recently been awarded to commence Airborne Electromagnetic surveying at a high priority area which includes the Kestrel Target.\nFigure 2 - Raptor Project tenements on colour Bouguer Gravity on TMI1VD grayscale aeromagnetic image, highlighting the Willowra Gravity Ridge & associated magnetic terrane hosting mafic-ultramafic intrusions\nIGO Raptor Project - updated October 2021\n1Edwards SE and Kellow M, 1996a. Annual Report for the Period 13 September 1994 to 12 September 1995, Tanami Project, EL6743, 6744 and 6745. Sons of Gwalia Limited. Open File Company Report, Northern Territory Geological Survey, CR1996-0011.", "pred_label": "__label__POS", "pred_score_pos": 0.5282517075538635} +{"content": "dc.description.abstract Beginning teachers often experience a range of challenges in their early years of teaching. From the complexities associated with planning sizeable learning sequences to the micro-skills required for classroom management, many beginning teachers can feel overwhelmed and become disenchanted with the work they do. Managing learning activities and differentiating for the diverse needs of every student in the classroom is a significant source of anxiety for many beginning teachers. Differentiation is, within itself, a complicated and involved process concerned not only with knowing students, but also with how to identify their needs and construct appropriate learning sequences for them. The consequence of self-doubt, confusion, and fear is that neither teacher nor students may get to experience the benefits of a well-differentiated classroom. This study employs a design-based research approach to explore how a personality-focused lens might be leveraged for the purposes of assisting two beginning teachers in junior-secondary classes to differentiate instruction. Through a series of iterative cycles, I worked with the beginning teachers as a co-participant, researcher, and mentor to support the designing of differentiated learning sequences. The cooperative and dialogic approach prompted a shift in the beginning teachers’ understandings of their self-efficacy and agency concerning differentiation. Data were collected through various sources including a baseline individual semi-structured interview, journaling, the collection of research artefacts, and a series of four dyadic semi-structured interviews. The data were thematically analysed and sorted into overarching themes that enabled or constrained the beginning teachers’ shifting experiences. The findings suggest that providing a space for the beginning teachers to critically reflect on, and extend, their pedagogical practices and understandings of differentiation supported the enactment of new methods for instruction.", "pred_label": "__label__POS", "pred_score_pos": 0.8586083650588989} +{"content": "Building from my article last fortnight, I am pleased to inform readers that the Worcestershire LEP has officially launched its new Plan for Growth, outlining the 20-year strategy for the county.\nThe new strategy was launched alongside the arrival of the National Net Zero Carbon Tour Bus in Worcester, which you will remember I discussed a few weeks back. The team presented the strategy at the Business Breakfast event which was run by the Worcestershire Growth Hub to help businesses access support to make sustainability changes.\nThe Plan for Growth showcases the challenges facing the 5 key areas of the Government’s Industrial Strategy which are, People, Place, Infrastructure, Business Environment, and Innovation. All of which have their own challenges which must be overcome to achieve the Worcestershire LEP’s vision of ‘a connected, creative, dynamic economy for all’.\nThe Worcestershire LEP have built the Plan for Growth upon the successes from the previous strategy document, including achievements such as securing two Careers Hubs to help better engage the business community with schools and education, securing one of the six initial Government funded 5G testbeds and unlocking infrastructure through the introduction of the first rail station in over 100 years in the county, Worcestershire Parkway.\nIt is important to note that the Plan for Growth has been built working closely with numerous partners across the county, to ensure a coherent and united approach to delivering on the action points in the strategy.\nAmplifying the physical launch we held, the Worcestershire LEP team have produced a series of digital content which includes videos focused on what the strategy means for the county, and the challenges facing the key development areas for the LEP, Business Support, Careers and Skills and Net Zero and Sustainability.\nI’d like to take a moment as so much has been delivered with the strategy we’ve had so far. This Plan for Growth is all about our evolution of the strategy to the next stage. We need to keep on building, keep on delivering the numbers, to the benefit of everybody within the county. This is not just about the businesses, everybody has got to win out of this.", "pred_label": "__label__POS", "pred_score_pos": 0.6666703820228577} +{"content": "Dec 31, 2018\nMany patients present to our emergency departments with worrisome symptoms, but we physicians can find no objective evidence that they have disease. In this episode, I present a hypothesis to explain what is causing this confusing situation. By offering our patients an understandable explanation for what is happening to them we can more effectively reassure them and begin the journey toward relief.", "pred_label": "__label__POS", "pred_score_pos": 0.999184250831604} +{"content": "Zooarchaeologists and geneticists are exploring how wolves and domestic dogs have been humanity’s predator, prey, and partner.\nA new finding suggests hominins left the African continent at least 500,000 years earlier than previously thought.\nA new theory challenges assumptions about when and how our ancestors altered their behaviors to boost brainpower.", "pred_label": "__label__POS", "pred_score_pos": 0.9680978059768677} +{"content": "Atlanta Pedestrian Accident Lawyer\nHelp Starts with The Champion Firm.\nOver $65 Million Won.\nNo Fees Unless You WinGet a Free Consult\nHablamos Espanol\nDon't accept less than what fair if you were struck by a reckless driver. We'll answer any questions and fight for everything you deserve.\nExperience & Service Matter. Pedestrian Accident Lawyer in Atlanta, GA\nWalking down the side of the road seems, at first, safer than driving. As a pedestrian, the hazards of large vehicles should not endanger you. Unfortunately, sometimes, you must share the road with those vehicles. Sometimes, those vehicles fail to share the road with you. In a pedestrian accident with a vehicle, the pedestrian often comes out with significant, severe injuries, many of which can cause life-changing results.\nLife After a Pedestrian Accident.\nAfter a pedestrian accident, you may find yourself left with serious injuries that make it difficult to move forward with your life. You may suffer:\nSpinal cord damage, including limited or even permanent paralysis Amputations Traumatic brain injuries Organ damage\nPedestrian accidents can leave you struggling with lifelong complications that transform your ability to do the things you have always done in the past: your ability to work, participate in leisure activities, and even care for yourself\nWe demand your settlement as soon as possible. Get What’s Fair After a Pedestrian Accident – Faster\nWe know the costs add up quickly for injured pedestrians. While some things take some time, we don’t wait around. As soon as it’s possible, we’ll demand a fair settlement. Our experiences and commitment help us resolve your claim quickly.\nWe never settle for less than what you deserve. The Cost of Hiring an Atlanta Pedestrian Accident Attorney.\nAfter a pedestrian accident, cost becomes a significant factor in many of your decisions. You do not want to miss out on any of the benefits of hiring an attorney, but you may worry that you cannot afford one.\nAt The Champion Firm, we are committed to helping our clients receive higher levels of compensation than they would receive on their own—even after they pay attorney fees. We accept personal injury cases on a contingent fee basis: our fee comes only as a portion of any compensation you receive. Not only that, we start with a free consultation, so we can discuss your claim and get to know the circumstances of your accident before diving into the claims process. That consultation can give you solid advice about how to proceed regardless of your injuries and your needs.\nClient Stories Dajaneshia | Car Accident Michael | Car Accident Natalia | Premises Liability Robyn | Slip and Fall Jake | Car Accident Sue | Slip and Fall Judith | Medical Malpractice Champion Firm Client | Motor Vehicle Accidents Wanda | Wrongful Death Champion Firm Client | Motor Vehicle Accident Walter | Motor Vehicle Accident Michael | Slip & Fall", "pred_label": "__label__POS", "pred_score_pos": 0.550955593585968} +{"content": "On Friday, September 23, 2021, the U.S. Environmental Protection Agency (EPA) issued the\nfinal rule to reduce the use of hydrofluorocarbons (HFCs) by 85% by 2036. The rule sets baselines for HFC production and consumption from which reductions can be measured and establishes a compliance and enforcement program. In addition to announcing the final rule, EPA also announced an interagency task force with the U.S. Department of Homeland Security to prevent the illegal import and trade of HFCs. (more…)\nU.S. President Joe Biden\nunveiled an initiative to promote the production and use of sustainable fuel in the aviation industry on Thursday, September 9. This initiative includes a goal to cut emissions in the aviation sector by 20% by 2030 and is part of the Administration’s goal to reach net-zero emissions by 2050. (more…)\nOn Friday, April 9, President Joe Biden released a $1.52 trillion fiscal year (FY) 2022 budget proposal. Referred to as the “skinny budget,” the document includes top-line figures and high-level summaries the White House will supplant with the full budget proposal later this spring. The release of the skinny budget starts the often-challenging process for Congress to pass an appropriations bill by the end of September, when the FY21 appropriations expire. (more…)\nIn an April 7 Agencywide\nmemorandum, U.S. Environmental Protection Agency (EPA or Agency) Administrator Michael Regan recommitted EPA to advancing environmental justice initiatives. Administrator Regan stated that it would be one of his “top priorities” to address environmental effects on communities whose residents are predominately of color, Indigenous, or low-income.", "pred_label": "__label__POS", "pred_score_pos": 0.5231771469116211} +{"content": "The price of Ether (ETH) is lagging Bitcoin's (BTC) price action by 13% in October, but is this relevant? To date, the altcoin has still outperformed BTC by 274% in 2021. However, traders tend to be short-sighted and some will question whether the Ethereum network can successfully migrate to proof of stake (PoS) validation and finally solve the high gas fees issue.\nMoreover, the increasing competition from smart contract networks like Solana (SOL) and Avalanche (AVAX) have been worrying investors:\nOne big problem with the “ETH is ultra sound money” meme is that EIP-1559 only limits the supply of ETH if Ethereum continues to have lots of transactions. It’s just as possible that people will tire of $80 gas fees and opt for one of numerous alternatives (SOL, AVAX, etc).— dennis in SF // OP_CTV (@pourteaux) October 8, 2021\nAccording to Cointelegraph, the recent speculation over the possible approval of a Bitcoin exchange-traded fund (ETF) raised traders' appetite for BTC. The U.S. Securities and Exchange Commission (SEC) is expected to announce its decision on multiple ETF requests over the next couple of weeks. However, it remains a possibility that the regulator will postpone these dates.\nPro traders are unfazed by the recent price stagnation\nTo determine whether professional traders are leaning bearish, one should start by analyzing the futures premium — also known as the basis rate. This indicator measures the price gap between futures contract prices and the regular spot market.\nEther's quarterly futures are the preferred instruments of whales and arbitrage desks. These derivatives might seem complicated for retail traders due to their settlement date and price difference from spot markets, but their most significant advantage is the lack of a fluctuating funding rate.\nThe three-month futures typically trade with a 5% to 15% annualized premium that follows the stablecoin lending rate. By postponing settlement, sellers demand a higher price, and this causes the price difference.\nAs depicted above, Ether's failure to break the $3,600 resistance has not caused a shift in pro traders' sentiment because the basis rate remains at a healthy 13%. This shows that there is no excessive optimism at the moment.\nRetail traders have been neutral for the past five weeks\nRetail traders tend to opt for perpetual contracts (inverse swaps), where a fee is charged every eight hours to balance the leverage demand. To understand if some panic selling occurred, one must analyze the futures markets funding rate.\nIn neutral markets, the funding rate tends to vary from 0% to 0.03% on the positive side. This fee is equivalent to 0.6% per week and indicates that longs are the ones paying it.\nSince Sept. 7, there hasn't been any real indication of high leverage demand from either bulls or bears. This balanced situation reflects retail traders' lack of appetite for leverage long positions, but at the same time shows little panic selling or excessive fear.\nDerivatives markets show that Ether investors are not worried about the recent underperformance versus Bitcoin. Furthermore, the lack of excessive long leverage after a 274% gain year-to-date should be positively portrayed.\nBy leaving some room for bullishness without compromising the derivatives market structure, Ether traders seem prepared for a rally above its all-time high, especially if a Bitcoin ETF is approved.\nThe views and opinions expressed here are solely those of the author and do not necessarily reflect the views of Cointelegraph. Every investment and trading move involves risk. You should conduct your own research when making a decision.", "pred_label": "__label__POS", "pred_score_pos": 0.7135707139968872} +{"content": "We are suffering: According to the Center for Hate and Extremism, Black people are the most hated race in America. Combine this experience with over 400 years of racism, discrimination, and second class citizenship along with the various forms of social control used to attempt to subjugate Black people (e.g., lynching and mass incarceration) and you have a race of people who have endured chronic generational trauma. The ongoing experience of chronic hate and generationally transmitted trauma have negatively influenced the physical and psychological health of Black individuals with many studies suggesting a strong link between chronic illness and racial trauma. We should go to therapy because we got a lot to talk about. We are resilient: Encoded in the DNA of every Black individual is the resourcefulness, strength, and connectedness that was needed to survive a metaphorical “splitting of self.” The Africans transported across the Middle Passage essentially had their cultures forcibly removed from them and had to recreate a sense of self from nothing with only memories and stories to guide them as the generations progressed. However, out of this process arose a Black culture that has been revered for its authenticity, creativeness, and ability to give voice and connect others. The process of therapy can help Black people to rediscover their resiliency. We get better: Although, Black individuals are the least likely of any racial group to seek out therapy services, we get better at rates equal to or greater than our counterparts when we engage in therapy. Recent research has found that around 80% of Black individuals who participate in therapy report a significant reduction in distress. Our natural way of being as a culture supports this process through our emphasis on relationship building, narration and verbal communication, emotional expression, and process orientation. Essentially, who we are as a people helps us get better through the process of therapy.", "pred_label": "__label__POS", "pred_score_pos": 0.682661771774292} +{"content": "References & Citations Bookmark(what is this?) Computer Science > Artificial Intelligence Title: Injecting Knowledge in Data-driven Vehicle Trajectory Predictors\n(Submitted on 8 Mar 2021)\nAbstract: Vehicle trajectory prediction tasks have been commonly tackled from two distinct perspectives: either with knowledge-driven methods or more recently with data-driven ones. On the one hand, we can explicitly implement domain-knowledge or physical priors such as anticipating that vehicles will follow the middle of the roads. While this perspective leads to feasible outputs, it has limited performance due to the difficulty to hand-craft complex interactions in urban environments. On the other hand, recent works use data-driven approaches which can learn complex interactions from the data leading to superior performance. However, generalization, \\textit{i.e.}, having accurate predictions on unseen data, is an issue leading to unrealistic outputs. In this paper, we propose to learn a \"Realistic Residual Block\" (RRB), which effectively connects these two perspectives. Our RRB takes any off-the-shelf knowledge-driven model and finds the required residuals to add to the knowledge-aware trajectory. Our proposed method outputs realistic predictions by confining the residual range and taking into account its uncertainty. We also constrain our output with Model Predictive Control (MPC) to satisfy kinematic constraints. Using a publicly available dataset, we show that our method outperforms previous works in terms of accuracy and generalization to new scenes. We will release our code and data split here: this https URL Submission historyFrom: Mohammadhossein Bahari [view email] [v1]Mon, 8 Mar 2021 16:03:09 GMT (3023kb,D)", "pred_label": "__label__POS", "pred_score_pos": 0.9110281467437744} +{"content": "K-Pop sensations BTS perform their hit song Permission to Dance in a video produced at the United Nations. The video accompanies the bands remarks at the SDG Moment and is meant to draw their audiences attention to the importance of Keeping the Promise of the Sustainable Development Goals and to inspire action.\nWhat is your promise? - un.cheerity.com/ ------- The SDG Moment serves to place an annual spotlight on the Sustainable Development Goals (SDGs) and will be held at the beginning of the United Nation’s General Assembly’s High-Level Week. It takes place as the world experiences a deeply uneven response to the COVID-19 pandemic, which risks creating a two-tier recovery with significant implications for the advancement of the SDGs, especially in developing countries. Convened by the UN Secretary-General Antonio Guterres, the Moment will provide world leaders with a platform to showcase the bold plans, actions and solutions that are needed to end the COVID-19 pandemic and set the world on course towards achieving the SDGs. Held in advance of major meetings on food systems, climate, energy, jobs and social protection, the SDG Moment event is expected to build the momentum needed to deliver on the Decade of Action and Keep the Promise of the SDGs.\n20 вер 2021", "pred_label": "__label__POS", "pred_score_pos": 0.7191988229751587} +{"content": "Depressed commodity prices, oversupply issues in the platinum sector, gold price gains offset by currency fluctuations, and simultaneous increases in costs, have led to leaner operations at many southern African mines.\nWhile this is an understandable reaction to the economic context, the financial benefits of developing smarter mining operations should not be overlooked in the drive to cut costs.\nMining operations are complex and there is often no automated flow of information to a single repository.\nThis results in a lack of “overall” clarity as to what is happening on the ground across the mining enterprise.\nAnd insightful decision-making cannot take place in an environment where all the facts are not at hand.\nMany tasks on mines are spatial in nature (e.g. locating and quantifying resource, planning drill and blast, movement of ore, managing environmental impact, etc.) and a wealth of geo-spatial information is collected in the process of addressing these tasks.\nThis treasure trove of captured data is usually not mined for additional seams of valuable information.\nIn addition, the lack of a centralised information portal often leads to data sitting in disjointed data silos in professional fiefdoms where it cannot be accessed for further departmental and enterprise-wide benefit.\nSmart organisations are\ndata driven.\nThey enable strategic decisions affecting the bottom line to be made based on credible information.\nFor this to take place in the mining environment there needs to be a seamless flow of data from various sources that can be easily accessed via a single portal.\nThe solution is a map-driven platform which allows data to be easily visualised, understood and analysed by users.\nThe data accessed via the platform enables users to make informed decisions regarding tactical day-to-day decisions and overall organisational policy, depending on their level of responsibility, by showing a holistic view of all relevant data related to the operation in a single dashboard.\nThis real-world “digital twin” enables users to identify unanticipated opportunities to enhance operational functionality.\nInterestingly, it is not always the complex data sets which provide the most value to mining enterprises.\nOften simply making key data sets readily accessible to users across the organisation reaps the most benefit.\nThe key to deriving maximum benefit from a central data portal is organisational buy-in.\nThe benefits of sharing data in this way needs to be communicated with a clear understanding of the value it can provide to mining professionals, departments and the enterprise as a whole.\nUsers also need to be rewarded for populating the portal with data and for using the data.\nLocation data is a valuable commodity on mines, and mining organisations should not overlook the role it can play in enhancing safety, productivity, profitability and efficiency within lean environments through its conversion into actionable intelligence.", "pred_label": "__label__POS", "pred_score_pos": 0.8043293952941895} +{"content": "Gene Banks, Seed Libraries, and Vegetable Sanctuaries: The Cultivation and Conservation of Heritage Vegetables in Britain, 1970–1985\ndc.contributor.author Curry, Helen en dc.date.accessioned 2019-06-10T23:30:14Z dc.date.available 2019-06-10T23:30:14Z dc.date.issued 2019-12-10 en dc.identifier.issn 1556-486X dc.identifier.uri https://www.repository.cam.ac.uk/handle/1810/293510 dc.description.abstract Individual seed saving and exchange are considered important components of contemporary efforts to conserve crop genetic diversity, which ramify at local, regional, and global scales. Yet the very fact that the contributions of these activities to conservation need to be made explicit by seed savers and those who study them indicates that the practices of seed saving and exchange may not immediately be recognized as conservation-oriented activities. This article investigates why and how individual seed saving came to be aligned with a broader conservation agenda in Britain through an historical examination of the promotion of seed saving by the Henry Doubleday Research Association (HDRA) in the 1970s and 1980s. It demonstrates how several HDRA initiatives that aimed to preserve vegetable diversity also re-inscribed British gardeners' ordinary labor as conservation work. This historical study complements sociological and ethnographic studies, highlighting the role of a prominent organization in creating pathways for individuals to engage in local, national, and international conservation through seed saving. It also serves as a reminder that the connections between these activities had to be made explicit—that is, that there was (and is) work involved in connecting individual acts of seed saving to conservation outcomes at different scales. dc.publisher American Anthropological Association dc.rights Attribution 4.0 International dc.rights.uri http://creativecommons.org/licenses/by/4.0/ dc.title Gene Banks, Seed Libraries, and Vegetable Sanctuaries: The Cultivation and Conservation of Heritage Vegetables in Britain, 1970–1985 en dc.type Article prism.endingPage 96 prism.issueIdentifier 2 en prism.publicationDate 2019 en prism.publicationName Culture, Agriculture, Food and Environment en prism.startingPage 87 prism.volume 46 en dc.identifier.doi 10.17863/CAM.40648 dcterms.dateAccepted 2019-05-31 en rioxxterms.versionofrecord 10.1111/cuag.12239 en rioxxterms.version AM rioxxterms.licenseref.uri http://creativecommons.org/licenses/by/4.0/ en rioxxterms.licenseref.startdate 2019-12-10 en dc.contributor.orcid Curry, Helen [0000-0001-9474-1528] dc.identifier.eissn 2153-9561 rioxxterms.type Journal Article/Review en pubs.funder-project-id WELLCOME TRUST (109337/Z/15/Z) cam.issuedOnline 2019-11-26 en dc.identifier.url https://anthrosource.onlinelibrary.wiley.com/doi/full/10.1111/cuag.12239 en Files in this item This item appears in the following Collection(s) Cambridge University Research Outputs Research outputs of the University of Cambridge", "pred_label": "__label__POS", "pred_score_pos": 0.648090124130249} +{"content": "The Decade of Action and Small Island Developing States: Measuring and addressing SIDS’ vulnerabilities to accelerate SDG progress\nSmall Island Developing States (SIDS) face a unique set of vulnerabilities which impede their ability to achieve sustainable development. Structural factors, including their size, remoteness, limited resource base, market size, exposure to climate risks and natural disasters impact socio economic outcomes and their ability to achieve the SDGs. The COVID19 pandemic amplified those vulnerabilities with many SIDS countries being particularly affected by the drop in international tourism and travels and international remittances. To support the UN effort to develop a sound and robust Multidimensional Vulnerability Index (MVI), this Working Paper presents a new pilot framework and MVI for tracking SIDS structural vulnerabilities by distinguishing across different SIDS categories.", "pred_label": "__label__POS", "pred_score_pos": 0.9253905415534973} +{"content": "The ice cream section of the frozen aisle at the grocery store has never been more competitive or saturated with options. In addition to dozens of flavors, you have low-fat and nonfat options. You have dairy-free and vegan options. You have locally and ethically sourced options.\nTo stand out from the crowd and deliver a customer experience that keeps people coming back, you need the right packaging.\nTraditionally, ice cream packaging has been made from wet-strength paperboard, which is lined with plastic to keep the package from deteriorating in the freezer. Of course, once you open one of those containers and start scooping, it loses its shape and becomes difficult to reseal, which can lead to leaks in the freezer.\nThis type of packaging also limits your design options. Colors tend to be muted and it’s difficult to use shiny, metallic finishes. These limitations are a big reason why so many ice cream products look similar on the shelf.\nCMG Plastics manufactures rigid plastic containers with in-mold labeling (IML) that overcome these limitations. Modern finishes and textures can be combined with vivid graphics and colors that are printed right into the plastic, creating a visual presentation that commands attention and enhances consumer perceptions.\nAt the same time, a clear container allows consumers to see what they’re buying. When you think about it, which do you think a customer would rather see, a photo of your ice cream on the package or the ice cream itself in the container?\nRigid plastic containers also maintain their shape after repeated use and are easily resealed to prevent leaks and maintain freshness. Once the customer finishes the ice cream, they can either rinse it out and use it for something else or recycle it. Our containers can be made with a percentage post-consumer recycled materials and offers a sustainable option that supports a circular economy.\nWe’re ready to help!\nCMG Plastics operates multiple in-mold labeling systems in manufacturing facilities in New Jersey and Canada. If you’d like to discuss how we can enhance your ice cream packaging using rigid, clear containers with IML, contact us today! We look forward to helping you and will get back to you promptly.", "pred_label": "__label__POS", "pred_score_pos": 0.5330525040626526} +{"content": "Measurement of lidocaine half-life before and after initiation of therapy in HIV-patients with various anti-viral regimens: A. Lidocaine half-life - expressed in minutes - was significantly lower in HIV-patients without ART. * p < 0.05, n = patients' number. B. Lidocaine half-life - measured 3 and 6 months (mo.) after initiation of ART - was almost identical with no obvious changes under antiretroviral treatment in patients with HIV-infection. C. Hepatitis C co-infection in HIV-patients had no significant influence on lidocaine half-life and activity of cytochrome p450.", "pred_label": "__label__POS", "pred_score_pos": 0.996019721031189} +{"content": "For only the second time since 1994, domestic cheese sales in the United States fell when compared to the previous year. In both instances, it took an economic shockwave to stop the sales ascent. Domestic demand fell 0.5% during the Great Recession of 2008. Likewise, purchases were off 0.1% in 2020 as COVID-19 gripped the world.\nOutside of those two market anomalies, cheese has been riding a high horse. If this dairy product was a rodeo participant, it would be a perennial winner destined for the Pro Rodeo Hall of Fame.\nUSDA released its annual per capita consumption data on September 30. Mozzarella, the star of the cheese aisle, fell 0.2% to a 12.3 pounds per person consumption figure. This was largely due to reduced restaurant sales as the pandemic unfolded.\nMozzarella married pizza long ago in an economic term known as a complement. In 1977, Americans consumed just 2.5 pounds of this Italian cheese. As the love affair with pizza unfolded, Mozzarella sales climbed to 8 pounds by 1997.\nAmerica’s next favorite cheese, Cheddar, essentially treaded water from 2019 to 2020, as sales moved from 11.16 to 11.20 pounds during that time span.\nTo comment, email your remarks to intel@hoards.com. Hoard's Dairyman Intel2021", "pred_label": "__label__POS", "pred_score_pos": 0.898003876209259} +{"content": "We will not write meal plans, as only Registered Dieticians are legally allowed to do so.\nWe use a variety of diet approaches, but we typically begin with a phase of tracking your intake to build awareness and nutritional knowledge. From there, depending on your goal, we may transition to targeting macronutrient ranges, otherwise known as flexible dieting, or we may transition away from tracking your intake and instead managing portion sizes and focusing on behavior change, moderation, and habit management.\nOur diet guidance will differ for each individual, since each client views food, diet, and making healthy lifestyle changes in a different way. We adapt accordingly to create the best avenue for long-term adherence and success for each individual we coach.\nOur approach to dieting is centered around making healthy lifestyle changes that will stick around, allowing you to maintain a healthy body composition and retain nutritional knowledge. The approach we use depends on what will be best for each client.", "pred_label": "__label__POS", "pred_score_pos": 0.7977091073989868} +{"content": "Doctors are responsible for identifying your health problems and prescribing an effective course of treatment. When a doctor makes a mistake and fails to perform a critical procedure, you could suffer severe physical or emotional harm. Regardless of why a failure occurred, a doctor’s potential negligence could lead to life-altering consequences.\nAn experienced Albany failure to perform a critical procedure attorney could help you hold a physician accountable for their error. There may be many legal options available, including filing a lawsuit for the damages you sustained, so you may seek compensation. A focused patient’s rights attorney could defend you during a medical malpractice claim.\nWhat is a Misdiagnosis?\nOne of the first steps to treating a patient is the diagnosis. This can help a doctor determine a course of care. When a doctor misdiagnoses a patient, the patient may not receive the care, medications, or critical procedures they need.\nFor example, if a doctor misdiagnoses a patient’s traumatic brain injury as a simple headache, that patient may not receive important diagnostic tests and lifesaving care. In some cases, a doctor may correct a misdiagnosis. However, if a delayed diagnosis causes a failure to provide a critical procedure, an Albany lawyer could help harmed people recover compensation.\nCritical Emergency Room Failures in Albany\nAnother reason that a doctor may fail to perform a necessary procedure is their volume of work. A doctor may be too rushed or busy and forget to schedule or perform the procedure. This commonly occurs in emergency rooms. Most patients who visit the emergency room need immediate medical attention, but hospitals often dedicate only a limited number of nurses and doctors to these areas.\nWhy Might a Physician Fail to Perform a Critical Procedure?\nIn the fast-paced emergency setting, a physician may unwittingly overlook a patient’s need for a critical procedure. Sometimes, the doctor may be caring for another patient and forget to order a test or perform a necessary step in a patient’s care plan. Even if the healthcare professional is unaware of their failure to provide a critical procedure, an attorney in Albany could work to hold them accountable.\nWhat Compensation Could Injured Patients Seek?\nWhen a doctor or other medical professional neglects to provide adequate care for their patients, resulting in harm or injury, the victim could seek compensation for the resulting damage.\nIn Albany, individuals harmed by a doctor’s negligence and failure to provide a necessary procedure could seek compensation for:\nMedical expenses Wages lost due to time from work Pain and suffering A wrongful death, if applicable\nDetermining the value of this compensation may be difficult. Following a doctor’s failure to perform a critical procedure, an attorney experienced in defending patients’ rights could quantify the level of harm. Understanding the value of harm could help an attorney fight for a potential damage awards that accurately reflects injury.\nResolving Failure to Perform Critical Procedure Cases\nThere are two ways an attorney in Albany could favorably resolve a legal claim stemming from the failure to perform a critical procedure. Many of these cases result in a monetary settlement. When settlements are not an option, litigation is the next best chance to secure fair compensation.\nMost of the time, malpractice cases resulting from the failure to perform a critical procedure are resolved through negotiated settlements. Doctors and other medical professionals typically enjoy substantial insurance coverage that protects them from third party liability claims. While these insurance providers are often willing to settle these claims, their initial offers are rarely reasonable or fair. Insurance companies aggressively pursue lowball settlement offers, especially when they are dealing with injured individuals without legal representation.\nThese aggressive tactics are common with plaintiffs that do not have an attorney but the right legal representation could convince the insurance company to make a reasonable offer to settle.\nThere are times when a settlement in these cases is impossible. Some defendants will adamantly deny failing to perform a critical procedure. These individuals often refuse to consider any settlement offer and instead demand a trial.\nNo matter what their reasoning, trials are a reality in some cases. When a trial becomes necessary, the benefits of hiring an attorney with litigation experience is clear. The right attorney could not only develop a winning trial strategy but also do so in a way that removes the stress and worry from the plaintiff. Aggressively pursuing a trial verdict is one way to secure a favorable outcome in these cases.\nThe Time Limit to File a Lawsuit\nAs is the case with any medical malpractice, there is a time limit on the ability to file an injury claim following the failure to perform a necessary procedure. The deadline that applies to these cases—the statute of limitations—is one of the primary pitfalls that can come with a malpractice case.\nThe statutory period for these cases lasts for two years and six months. This 30-month period begins to expire on the date that the act of malpractice occurs. While this date is easy to identify when it comes to surgical errors, it can be more challenging in cases involving the failure to perform a critical procedure. That is because there is no clear date of when the malpractice occurs in these cases.\nGiven the complications that come with the statute of limitations, it is important to seek the guidance of an attorney. A seasoned lawyer could ensure that a lawsuit complies with the statute.\nThe consequences of failing to file a malpractice lawsuit before the statute of limitations expires can have dire consequences for a claim for compensation. Typically, the court will dismiss a failure to perform a critical procedure lawsuit with prejudice if it is filed after the deadline. This will bring a malpractice case to abrupt and permanent end, even if there is no doubt as to the existence of negligence. The guidance of an attorney could help to avoid these pitfalls.\nAn Albany Failure to Perform Attorney is Available to Help\nOften, critical procedures need to be performed as quickly as possible to prevent further damage. When a doctor fails to perform a critical procedure, the consequences can be serious. If your doctor neglected to order a test, failed to schedule you for surgery, or otherwise failed to treat your illness or injury, you may be able to recover compensation. A compassionate and skilled Albany failure to perform a critical procedure lawyer could review your case and explain how they may help. Reach out today to learn more.", "pred_label": "__label__POS", "pred_score_pos": 0.9818992614746094} +{"content": "Accurate and confident energy production estimates are central to the efficient financing of solar energy projects. In 2019, DNV issued a white paper on the validation study of our own preconstruction energy assessments for utility-scale solar projects. One key finding from our previous study was that utility-scale solar projects, on average, were underperforming expectations by 3.1%, on a weather-adjusted basis.\nWe continue to invest in validating our preconstruction solar energy assessments against actual operating data in a process of continuous improvement. Since 2019, we have identified three methodology refinements that can reduce this shortfall: terrain, sub-hourly clipping and wind stow. Our new white paper is the addendum to our 2019 Solar Energy Assessment Validation Study and expands on the previous paper to evaluate the impact of subsequent methodology refinements.", "pred_label": "__label__POS", "pred_score_pos": 0.8746078610420227} +{"content": "On a typical day, you will find me seated before 25 community college students. Often I think, “Pinch me; I’m dreaming! Teaching is the most honored profession in the Universe.” Other days, I am nonplussed by the palm-sized babysitters, distractors and anxiety-soothers we call cell phones. Despite my efforts to challenge and inspire, students remain plugged in and tuned out. They are a constant, nagging reminder that disconnecting from technology is the only way back to a real, substantial and healthy life.\nFrom 2002-2005, I taught at Oglala Lakota College in South Dakota. I loved my Native students. I would relay an assignment and sit back. For the first 20 minutes, they would gaze vacantly as though at some invisible screen. I would get the dreads. I’d think, “Oh, no. They hate this project. I’m done!” In a matter of minutes, the room would be abuzz, not with sound, but with the vital energy of engagement. The students would cut, paste, read, think, write and think some more. By the end of class, they had created impeccable works of scholarship and art.\nI do not know how they fare now, as I have not returned since 2005. I can say with certainty that, at the time, concentrating in class or connecting to Gaia came naturally to the Lakota, who for a long time remained immune to the allure of the flip phone. Prior to the invasion of cell phones, news traveled by what is affectionately termed “the Moccasin Telegraph,” that mysterious\nje ne sais quoi method by which information, events, and gossip swiftly spread throughout the Native community — all without help from broadcast networks or radio towers.\nMy current crop of students spend their days with phone in hand or bud in ear. Contact with the natural realm — or any real plane of existence other than the technological — is an afterthought. Life ensues in the virtual realm of social media and the Internet. They will likely not pause to gauge the thickness of a squirrel’s fur and its predictive connection to the imminent onslaught of frigid weather. They are not inclined to attend to the conversation of crows, avian friends and messengers. They feign no interest in the waning of a fingernail moon, the popping of early spring buds or the sluicing of winter melt water, undulating in oily, rainbowy rivulets over the asphalt. All of these are, instead, “experienced” by clicking on a gif, YouTube video, Instagram or Snapchat.\nWhile I’m not in the business of conversion, I do see it as part of my job as educator to foster and facilitate the learning process. I want my students to experience the joy of discovering an unlimited well of ideas and creativity available by accessing the vibrant domains of self and Nature. Unlike my students at the tribal college, my Normandale students at present respond to new tasks with visible agitation, a flood of questions, and more than a few cleverly disguised attempts to bamboozle me into talking them through every micro-step and nuance of what ought to be their assignment. Were they simply to take a walk in nature to gather their shakes, they could easily uncover a wealth of inspiration through their own observations, talents and original creative ideas.\nYears ago, I had the impetus to write a treatise entitled “Spiritual Pedagogy.” Alas, I waited too long: that phrase has since taken hold in books and scholarly journals everywhere. Still, I hold fast to its source, which lies in Cedric Red Feather’s Mandan spiritual wisdom. He has taught, and still maintains, that there are four parts of a person: the spiritual, physical, mental and emotional/social. Address the spiritual, and all of the others fall in line.\nI cannot prescribe for anyone a particular path to the spiritual — for you must find it on your own. It may be as close as your own backyard. Take a walk within the natural world; listen intently to the super-numerous beings all around us. Therein lies the road back from your technological Emerald City. All you need do is click your heels three times and recite, “There’s no nourishment like Gaia. There’s no nourishment like Gaia.”", "pred_label": "__label__POS", "pred_score_pos": 0.5753944516181946}