Daily Papers

Autonomous driving technology, a catalyst for revolutionizing transportation and urban mobility, has the tend to transition from rule-based systems to data-driven strategies. Traditional module-based systems are constrained by cumulative errors among cascaded modules and inflexible pre-set rules. In contrast, end-to-end autonomous driving systems have the potential to avoid error accumulation due to their fully data-driven training process, although they often lack transparency due to their "black box" nature, complicating the validation and traceability of decisions. Recently, large language models (LLMs) have demonstrated abilities including understanding context, logical reasoning, and generating answers. A natural thought is to utilize these abilities to empower autonomous driving. By combining LLM with foundation vision models, it could open the door to open-world understanding, reasoning, and few-shot learning, which current autonomous driving systems are lacking. In this paper, we systematically review a research line about Large Language Models for Autonomous Driving (LLM4AD). This study evaluates the current state of technological advancements, distinctly outlining the principal challenges and prospective directions for the field. For the convenience of researchers in academia and industry, we provide real-time updates on the latest advances in the field as well as relevant open-source resources via the designated link: https://github.com/Thinklab-SJTU/Awesome-LLM4AD.

Foundation models have revolutionized artificial intelligence across numerous domains, yet their transformative potential remains largely untapped in Extreme Multi-label Classification (XMC). Queries in XMC are associated with relevant labels from extremely large label spaces, where it is critical to strike a balance between efficiency and performance. Therefore, many recent approaches efficiently pose XMC as a maximum inner product search between embeddings learned from small encoder-only transformer architectures. In this paper, we address two important aspects in XMC: how to effectively harness larger decoder-only models, and how to exploit visual information while maintaining computational efficiency. We demonstrate that both play a critical role in XMC separately and can be combined for improved performance. We show that a few billion-size decoder can deliver substantial improvements while keeping computational overhead manageable. Furthermore, our Vision-enhanced eXtreme Multi-label Learning framework (ViXML) efficiently integrates foundation vision models by pooling a single embedding per image. This limits computational growth while unlocking multi-modal capabilities. Remarkably, ViXML with small encoders outperforms text-only decoder in most cases, showing that an image is worth billions of parameters. Finally, we present an extension of existing text-only datasets to exploit visual metadata and make them available for future benchmarking. Comprehensive experiments across four public text-only datasets and their corresponding image enhanced versions validate our proposals' effectiveness, surpassing previous state-of-the-art by up to +8.21\% in P@1 on the largest dataset. ViXML's code is available at https://github.com/DiegoOrtego/vixml.

To mimic human vision with the way of recognizing the diverse and open world, foundation vision models are much critical. While recent techniques of self-supervised learning show the promising potentiality of this mission, we argue that signals from labelled data are also important for common-sense recognition, and properly chosen pre-text tasks can facilitate the efficiency of vision representation learning. To this end, we propose a novel pre-training framework by adopting both self-supervised and supervised visual pre-text tasks in a multi-task manner. Specifically, given an image, we take a heuristic way by considering its intrinsic style properties, inside objects with their locations and correlations, and how it looks like in 3D space for basic visual understanding. However, large-scale object bounding boxes and correlations are usually hard to achieve. Alternatively, we develop a hybrid method by leveraging both multi-label classification and self-supervised learning. On the one hand, under the multi-label supervision, the pre-trained model can explore the detailed information of an image, e.g., image types, objects, and part of semantic relations. On the other hand, self-supervised learning tasks, with respect to Masked Image Modeling (MIM) and contrastive learning, can help the model learn pixel details and patch correlations. Results show that our pre-trained models can deliver results on par with or better than state-of-the-art (SOTA) results on multiple visual tasks. For example, with a vanilla Swin-B backbone, we achieve 85.3\% top-1 accuracy on ImageNet-1K classification, 47.9 box AP on COCO object detection for Mask R-CNN, and 50.6 mIoU on ADE-20K semantic segmentation when using Upernet. The performance shows the ability of our vision foundation model to serve general purpose vision tasks.

Accurately detecting and classifying damage in analogue media such as paintings, photographs, textiles, mosaics, and frescoes is essential for cultural heritage preservation. While machine learning models excel in correcting degradation if the damage operator is known a priori, we show that they fail to robustly predict where the damage is even after supervised training; thus, reliable damage detection remains a challenge. Motivated by this, we introduce ARTeFACT, a dataset for damage detection in diverse types analogue media, with over 11,000 annotations covering 15 kinds of damage across various subjects, media, and historical provenance. Furthermore, we contribute human-verified text prompts describing the semantic contents of the images, and derive additional textual descriptions of the annotated damage. We evaluate CNN, Transformer, diffusion-based segmentation models, and foundation vision models in zero-shot, supervised, unsupervised and text-guided settings, revealing their limitations in generalising across media types. Our dataset is available at https://daniela997.github.io/ARTeFACT/{https://daniela997.github.io/ARTeFACT/} as the first-of-its-kind benchmark for analogue media damage detection and restoration.

Deep reinforcement learning has achieved remarkable success in learning control policies from pixels across a wide range of tasks, yet its application remains hindered by low sample efficiency, requiring significantly more environment interactions than humans to reach comparable performance. Model-based reinforcement learning (MBRL) offers a solution by leveraging learnt world models to generate simulated experience, thereby improving sample efficiency. However, in visually complex environments, small or dynamic elements can be critical for decision-making. Yet, traditional MBRL methods in pixel-based environments typically rely on auto-encoding with an L_2 loss, which is dominated by large areas and often fails to capture decision-relevant details. To address these limitations, we propose an object-centric MBRL pipeline, which integrates recent advances in computer vision to allow agents to focus on key decision-related elements. Our approach consists of four main steps: (1) annotating key objects related to rewards and goals with segmentation masks, (2) extracting object features using a pre-trained, frozen foundation vision model, (3) incorporating these object features with the raw observations to predict environmental dynamics, and (4) training the policy using imagined trajectories generated by this object-centric world model. Building on the efficient MBRL algorithm STORM, we call this pipeline OC-STORM. We demonstrate OC-STORM's practical value in overcoming the limitations of conventional MBRL approaches on both Atari games and the visually complex game Hollow Knight.

Modern Vision-Language Models (VLMs) have achieved impressive performance in various tasks, yet they often struggle with compositional reasoning, the ability to decompose and recombine concepts to solve novel problems. While neuro-symbolic approaches offer a promising direction, they are typically constrained by crisp logical execution or predefined predicates, which limit flexibility. In this work, we introduce NePTune, a neuro-symbolic framework that overcomes these limitations through a hybrid execution model that integrates the perception capabilities of foundation vision models with the compositional expressiveness of symbolic reasoning. NePTune dynamically translates natural language queries into executable Python programs that blend imperative control flow with soft logic operators capable of reasoning over VLM-generated uncertainty. Operating in a training-free manner, NePTune, with a modular design, decouples perception from reasoning, yet its differentiable operations support fine-tuning. We evaluate NePTune on multiple visual reasoning benchmarks and various domains, utilizing adversarial tests, and demonstrate a significant improvement over strong base models, as well as its effective compositional generalization and adaptation capabilities in novel environments.

Images of the natural world, collected by a variety of cameras, from drones to individual phones, are increasingly abundant sources of biological information. There is an explosion of computational methods and tools, particularly computer vision, for extracting biologically relevant information from images for science and conservation. Yet most of these are bespoke approaches designed for a specific task and are not easily adaptable or extendable to new questions, contexts, and datasets. A vision model for general organismal biology questions on images is of timely need. To approach this, we curate and release TreeOfLife-10M, the largest and most diverse ML-ready dataset of biology images. We then develop BioCLIP, a foundation model for the tree of life, leveraging the unique properties of biology captured by TreeOfLife-10M, namely the abundance and variety of images of plants, animals, and fungi, together with the availability of rich structured biological knowledge. We rigorously benchmark our approach on diverse fine-grained biology classification tasks, and find that BioCLIP consistently and substantially outperforms existing baselines (by 17% to 20% absolute). Intrinsic evaluation reveals that BioCLIP has learned a hierarchical representation conforming to the tree of life, shedding light on its strong generalizability. Our code, models and data will be made available at https://github.com/Imageomics/bioclip.

Foundation vision or vision-language models are trained on large unlabeled or noisy data and learn robust representations that can achieve impressive zero- or few-shot performance on diverse tasks. Given these properties, they are a natural fit for active learning (AL), which aims to maximize labeling efficiency. However, the full potential of foundation models has not been explored in the context of AL, specifically in the low-budget regime. In this work, we evaluate how foundation models influence three critical components of effective AL, namely, 1) initial labeled pool selection, 2) ensuring diverse sampling, and 3) the trade-off between representative and uncertainty sampling. We systematically study how the robust representations of foundation models (DINOv2, OpenCLIP) challenge existing findings in active learning. Our observations inform the principled construction of a new simple and elegant AL strategy that balances uncertainty estimated via dropout with sample diversity. We extensively test our strategy on many challenging image classification benchmarks, including natural images as well as out-of-domain biomedical images that are relatively understudied in the AL literature. We also provide a highly performant and efficient implementation of modern AL strategies (including our method) at https://github.com/sanketx/AL-foundation-models.

We explore adapting foundation models (FMs) from the computer vision domain to geoscience. FMs, large neural networks trained on massive datasets, excel in diverse tasks with remarkable adaptability and generality. However, geoscience faces challenges like lacking curated training datasets and high computational costs for developing specialized FMs. This study considers adapting FMs from computer vision to geoscience, analyzing their scale, adaptability, and generality for geoscientific data analysis. We introduce a workflow that leverages existing computer vision FMs, fine-tuning them for geoscientific tasks, reducing development costs while enhancing accuracy. Through experiments, we demonstrate this workflow's effectiveness in broad applications to process and interpret geoscientific data of lunar images, seismic data, DAS arrays and so on. Our findings introduce advanced ML techniques to geoscience, proving the feasibility and advantages of cross-domain FMs adaptation, driving further advancements in geoscientific data analysis and offering valuable insights for FMs applications in other scientific domains.

Image-text retrieval has become a fundamental component in intelligent multimedia systems; however, most existing vision-language models are optimized for highresource languages and remain suboptimal for low-resource settings such as Vietnamese. This work introduces ViCLIP-OT, a foundation vision-language model specifically designed for Vietnamese image-text retrieval. The proposed framework integrates CLIP-style contrastive learning with a Similarity-Graph Regularized Optimal Transport (SIGROT) loss to enhance global cross-modal consistency and mitigate modality gap issues. Extensive experiments on three Vietnamese benchmarks (UITOpenViIC, KTVIC, and Crossmodal-3600) demonstrate that ViCLIP-OT consistently outperforms CLIP and SigLIP baselines in both in-domain and zero-shot settings. On UIT-OpenViIC, the model achieves an average Recall@K of 67.34%, improving upon CLIP by 5.75 percentage points. In zero-shot evaluation on Crossmodal-3600, ViCLIPOT surpasses CLIP by 11.72 percentage points. Embedding-space analysis further confirms improved alignment and reduced modality gap. The results indicate that integrating SIGROT provides an effective and scalable strategy for cross-modal retrieval in low-resource languages, offering practical implications for intelligent multimedia retrieval systems in Vietnamese and other underrepresented linguistic contexts.

In studies of transferable learning, scaling laws are obtained for various important foundation models to predict their properties and performance at larger scales. We show here how scaling law derivation can also be used for model and dataset comparison, allowing to decide which procedure is to be preferred for pre-training. For the first time, full scaling laws based on dense measurements across a wide span of model and samples seen scales are derived for two important language-vision learning procedures, CLIP and MaMMUT, that use either contrastive only or contrastive and captioning text generative loss. Ensuring sufficient prediction accuracy for held out points, we use derived scaling laws to compare both models, obtaining evidence for MaMMUT's stronger improvement with scale and better sample efficiency than standard CLIP. To strengthen validity of the comparison, we show scaling laws for various downstream tasks, classification, retrieval, and segmentation, and for different open datasets, DataComp, DFN and Re-LAION, observing consistently the same trends. We show that comparison can also be performed when deriving scaling laws with a constant learning rate schedule, reducing compute cost. Accurate derivation of scaling laws provides thus means to perform model and dataset comparison across scale spans, avoiding misleading conclusions based on measurements from single reference scales only, paving the road for systematic comparison and improvement of open foundation models and datasets for their creation. We release all the pre-trained models with their intermediate checkpoints, including openMaMMUT-L/14, which achieves 80.3% zero-shot ImageNet-1k accuracy, trained on 12.8B samples from DataComp-1.4B. Code for reproducing experiments in the paper and raw experiments data can be found at https://github.com/LAION-AI/scaling-laws-for-comparison.

Foundation vision-language models are currently transforming computer vision, and are on the rise in medical imaging fueled by their very promising generalization capabilities. However, the initial attempts to transfer this new paradigm to medical imaging have shown less impressive performances than those observed in other domains, due to the significant domain shift and the complex, expert domain knowledge inherent to medical-imaging tasks. Motivated by the need for domain-expert foundation models, we present FLAIR, a pre-trained vision-language model for universal retinal fundus image understanding. To this end, we compiled 37 open-access, mostly categorical fundus imaging datasets from various sources, with up to 97 different target conditions and 284,660 images. We integrate the expert's domain knowledge in the form of descriptive textual prompts, during both pre-training and zero-shot inference, enhancing the less-informative categorical supervision of the data. Such a textual expert's knowledge, which we compiled from the relevant clinical literature and community standards, describes the fine-grained features of the pathologies as well as the hierarchies and dependencies between them. We report comprehensive evaluations, which illustrate the benefit of integrating expert knowledge and the strong generalization capabilities of FLAIR under difficult scenarios with domain shifts or unseen categories. When adapted with a lightweight linear probe, FLAIR outperforms fully-trained, dataset-focused models, more so in the few-shot regimes. Interestingly, FLAIR outperforms by a large margin more generalist, larger-scale image-language models, which emphasizes the potential of embedding experts' domain knowledge and the limitations of generalist models in medical imaging.

Foundation Vision Language Models (VLMs) exhibit strong capabilities in multi-modal representation learning, comprehension, and reasoning. By injecting action components into the VLMs, Vision-Language-Action Models (VLAs) can be naturally formed and also show promising performance. Existing work has demonstrated the effectiveness and generalization of VLAs in multiple scenarios and tasks. Nevertheless, the transfer from VLMs to VLAs is not trivial since existing VLAs differ in their backbones, action-prediction formulations, data distributions, and training recipes. This leads to a missing piece for a systematic understanding of the design choices of VLAs. In this work, we disclose the key factors that significantly influence the performance of VLA and focus on answering three essential design choices: which backbone to select, how to formulate the VLA architectures, and when to add cross-embodiment data. The obtained results convince us firmly to explain why we need VLA and develop a new family of VLAs, RoboVLMs, which require very few manual designs and achieve a new state-of-the-art performance in three simulation tasks and real-world experiments. Through our extensive experiments, which include over 8 VLM backbones, 4 policy architectures, and over 600 distinct designed experiments, we provide a detailed guidebook for the future design of VLAs. In addition to the study, the highly flexible RoboVLMs framework, which supports easy integrations of new VLMs and free combinations of various design choices, is made public to facilitate future research. We open-source all details, including codes, models, datasets, and toolkits, along with detailed training and evaluation recipes at: robovlms.github.io.

Learning generalist embodied agents, able to solve multitudes of tasks in different domains is a long-standing problem. Reinforcement learning (RL) is hard to scale up as it requires a complex reward design for each task. In contrast, language can specify tasks in a more natural way. Current foundation vision-language models (VLMs) generally require fine-tuning or other adaptations to be functional, due to the significant domain gap. However, the lack of multimodal data in such domains represents an obstacle toward developing foundation models for embodied applications. In this work, we overcome these problems by presenting multimodal foundation world models, able to connect and align the representation of foundation VLMs with the latent space of generative world models for RL, without any language annotations. The resulting agent learning framework, GenRL, allows one to specify tasks through vision and/or language prompts, ground them in the embodied domain's dynamics, and learns the corresponding behaviors in imagination. As assessed through large-scale multi-task benchmarking, GenRL exhibits strong multi-task generalization performance in several locomotion and manipulation domains. Furthermore, by introducing a data-free RL strategy, it lays the groundwork for foundation model-based RL for generalist embodied agents.

Large-scale but noisy image-text pair data have paved the way for the success of Contrastive Language-Image Pretraining (CLIP). As the foundation vision encoder, CLIP in turn serves as the cornerstone for most large vision-language models (LVLMs). This interdependence naturally raises an interesting question: Can we reciprocally leverage LVLMs to enhance the quality of image-text pair data, thereby opening the possibility of a self-reinforcing cycle for continuous improvement? In this work, we take a significant step toward this vision by introducing an LVLM-driven data refinement pipeline. Our framework leverages LVLMs to process images and their raw alt-text, generating four complementary textual formulas: long positive descriptions, long negative descriptions, short positive tags, and short negative tags. Applying this pipeline to the curated DFN-Large dataset yields VLM-150M, a refined dataset enriched with multi-grained annotations. Based on this dataset, we further propose a training paradigm that extends conventional contrastive learning by incorporating negative descriptions and short tags as additional supervised signals. The resulting model, namely HQ-CLIP, demonstrates remarkable improvements across diverse benchmarks. Within a comparable training data scale, our approach achieves state-of-the-art performance in zero-shot classification, cross-modal retrieval, and fine-grained visual understanding tasks. In retrieval benchmarks, HQ-CLIP even surpasses standard CLIP models trained on the DFN-2B dataset, which contains 10times more training data than ours. All code, data, and models are available at https://zxwei.site/hqclip.

Large language models, trained on extensive corpora, successfully unify diverse linguistic tasks within a single generative framework. Inspired by this, recent works like Large Vision Model (LVM) extend this paradigm to vision by organizing tasks into sequential visual sentences, where visual prompts serve as the context to guide outputs. However, such modeling requires task-specific pre-training across modalities and sources, which is costly and limits scalability to unseen tasks. Given that pre-trained video generation models inherently capture temporal sequence dependencies, we explore a more unified and scalable alternative: can a pre-trained video generation model adapt to diverse image and video tasks? To answer this, we propose UniVid, a framework that fine-tunes a video diffusion transformer to handle various vision tasks without task-specific modifications. Tasks are represented as visual sentences, where the context sequence defines both the task and the expected output modality. We evaluate the generalization of UniVid from two perspectives: (1) cross-modal inference with contexts composed of both images and videos, extending beyond LVM's uni-modal setting; (2) cross-source tasks from natural to annotated data, without multi-source pre-training. Despite being trained solely on natural video data, UniVid generalizes well in both settings. Notably, understanding and generation tasks can easily switch by simply reversing the visual sentence order in this paradigm. These findings highlight the potential of pre-trained video generation models to serve as a scalable and unified foundation for vision modeling. Our code will be released at https://github.com/CUC-MIPG/UniVid.

Medical image segmentation allows quantifying target structure size and shape, aiding in disease diagnosis, prognosis, surgery planning, and comprehension.Building upon recent advancements in foundation Vision-Language Models (VLMs) from natural image-text pairs, several studies have proposed adapting them to Vision-Language Segmentation Models (VLSMs) that allow using language text as an additional input to segmentation models. Introducing auxiliary information via text with human-in-the-loop prompting during inference opens up unique opportunities, such as open vocabulary segmentation and potentially more robust segmentation models against out-of-distribution data. Although transfer learning from natural to medical images has been explored for image-only segmentation models, the joint representation of vision-language in segmentation problems remains underexplored. This study introduces the first systematic study on transferring VLSMs to 2D medical images, using carefully curated 11 datasets encompassing diverse modalities and insightful language prompts and experiments. Our findings demonstrate that although VLSMs show competitive performance compared to image-only models for segmentation after finetuning in limited medical image datasets, not all VLSMs utilize the additional information from language prompts, with image features playing a dominant role. While VLSMs exhibit enhanced performance in handling pooled datasets with diverse modalities and show potential robustness to domain shifts compared to conventional segmentation models, our results suggest that novel approaches are required to enable VLSMs to leverage the various auxiliary information available through language prompts. The code and datasets are available at https://github.com/naamiinepal/medvlsm.

Foundation Vision-Language Models (VLMs) trained using large-scale open-domain images and text pairs have recently been adapted to develop Vision-Language Segmentation Models (VLSMs) that allow providing text prompts during inference to guide image segmentation. If robust and powerful VLSMs can be built for medical images, it could aid medical professionals in many clinical tasks where they must spend substantial time delineating the target structure of interest. VLSMs for medical images resort to fine-tuning base VLM or VLSM pretrained on open-domain natural image datasets due to fewer annotated medical image datasets; this fine-tuning is resource-consuming and expensive as it usually requires updating all or a significant fraction of the pretrained parameters. Recently, lightweight blocks called adapters have been proposed in VLMs that keep the pretrained model frozen and only train adapters during fine-tuning, substantially reducing the computing resources required. We introduce a novel adapter, VLSM-Adapter, that can fine-tune pretrained vision-language segmentation models using transformer encoders. Our experiments in widely used CLIP-based segmentation models show that with only 3 million trainable parameters, the VLSM-Adapter outperforms state-of-the-art and is comparable to the upper bound end-to-end fine-tuning. The source code is available at: https://github.com/naamiinepal/vlsm-adapter.

People say, "A picture is worth a thousand words". Then how can we get the rich information out of the image? We argue that by using visual clues to bridge large pretrained vision foundation models and language models, we can do so without any extra cross-modal training. Thanks to the strong zero-shot capability of foundation models, we start by constructing a rich semantic representation of the image (e.g., image tags, object attributes / locations, captions) as a structured textual prompt, called visual clues, using a vision foundation model. Based on visual clues, we use large language model to produce a series of comprehensive descriptions for the visual content, which is then verified by the vision model again to select the candidate that aligns best with the image. We evaluate the quality of generated descriptions by quantitative and qualitative measurement. The results demonstrate the effectiveness of such a structured semantic representation.

Canonical surface mapping generalizes keypoint detection by assigning each pixel of an object to a corresponding point in a 3D template. Popularised by DensePose for the analysis of humans, authors have since attempted to apply the concept to more categories, but with limited success due to the high cost of manual supervision. In this work, we introduce SHIC, a method to learn canonical maps without manual supervision which achieves better results than supervised methods for most categories. Our idea is to leverage foundation computer vision models such as DINO and Stable Diffusion that are open-ended and thus possess excellent priors over natural categories. SHIC reduces the problem of estimating image-to-template correspondences to predicting image-to-image correspondences using features from the foundation models. The reduction works by matching images of the object to non-photorealistic renders of the template, which emulates the process of collecting manual annotations for this task. These correspondences are then used to supervise high-quality canonical maps for any object of interest. We also show that image generators can further improve the realism of the template views, which provide an additional source of supervision for the model.

Recent success of pre-trained foundation vision-language models makes Open-Vocabulary Segmentation (OVS) possible. Despite the promising performance, this approach introduces heavy computational overheads for two challenges: 1) large model sizes of the backbone; 2) expensive costs during the fine-tuning. These challenges hinder this OVS strategy from being widely applicable and affordable in real-world scenarios. Although traditional methods such as model compression and efficient fine-tuning can address these challenges, they often rely on heuristics. This means that their solutions cannot be easily transferred and necessitate re-training on different models, which comes at a cost. In the context of efficient OVS, we target achieving performance that is comparable to or even better than prior OVS works based on large vision-language foundation models, by utilizing smaller models that incur lower training costs. The core strategy is to make our efficiency principled and thus seamlessly transferable from one OVS framework to others without further customization. Comprehensive experiments on diverse OVS benchmarks demonstrate our superior trade-off between segmentation accuracy and computation costs over previous works. Our code is available on https://github.com/Xujxyang/OpenTrans

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for various radiological tasks. CT-FM was pre-trained using 148,000 computed tomography (CT) scans from the Imaging Data Commons through label-agnostic contrastive learning. We evaluated CT-FM across four categories of tasks, namely, whole-body and tumor segmentation, head CT triage, medical image retrieval, and semantic understanding, showing superior performance against state-of-the-art models. Beyond quantitative success, CT-FM demonstrated the ability to cluster regions anatomically and identify similar anatomical and structural concepts across scans. Furthermore, it remained robust across test-retest settings and indicated reasonable salient regions attached to its embeddings. This study demonstrates the value of large-scale medical imaging foundation models and by open-sourcing the model weights, code, and data, aims to support more adaptable, reliable, and interpretable AI solutions in radiology.

Leveraging the powerful representations of pre-trained vision foundation models -- traditionally used for visual comprehension -- we explore a novel direction: building an image tokenizer directly atop such models, a largely underexplored area. Specifically, we employ a frozen vision foundation model as the encoder of our tokenizer. To enhance its effectiveness, we introduce two key components: (1) a region-adaptive quantization framework that reduces redundancy in the pre-trained features on regular 2D grids, and (2) a semantic reconstruction objective that aligns the tokenizer's outputs with the foundation model's representations to preserve semantic fidelity. Based on these designs, our proposed image tokenizer, VFMTok, achieves substantial improvements in image reconstruction and generation quality, while also enhancing token efficiency. It further boosts autoregressive (AR) generation -- achieving a gFID of 2.07 on ImageNet benchmarks, while accelerating model convergence by three times, and enabling high-fidelity class-conditional synthesis without the need for classifier-free guidance (CFG). The code will be released publicly to benefit the community.

Vision foundation models trained via multi-teacher distillation offer a promising path toward unified visual representations, yet the learning dynamics and data efficiency of such approaches remain underexplored. In this paper, we systematically study multi-teacher distillation for vision foundation models and identify key factors that enable training at lower computational cost. We introduce Agglomerative Mixture-of-Experts Vision Foundation Models (AMoE), which distill knowledge from SigLIP2 and DINOv3 simultaneously into a Mixture-of-Experts student. We show that (1) our Asymmetric Relation-Knowledge Distillation loss preserves the geometric properties of each teacher while enabling effective knowledge transfer, (2) token-balanced batching that packs varying-resolution images into sequences with uniform token budgets stabilizes representation learning across resolutions without sacrificing performance, and (3) hierarchical clustering and sampling of training data--typically reserved for self-supervised learning--substantially improves sample efficiency over random sampling for multi-teacher distillation. By combining these findings, we curate OpenLVD200M, a 200M-image corpus that demonstrates superior efficiency for multi-teacher distillation. Instantiated in a Mixture-of-Experts. We release OpenLVD200M and distilled models.

The performance of Latent Diffusion Models (LDMs) is critically dependent on the quality of their visual tokenizer. While recent works have explored incorporating Vision Foundation Models (VFMs) via distillation, we identify a fundamental flaw in this approach: it inevitably weakens the robustness of alignment with the original VFM, causing the aligned latents to deviate semantically under distribution shifts. In this paper, we bypass distillation by proposing a more direct approach: Vision Foundation Model Variational Autoencoder (VFM-VAE). To resolve the inherent tension between the VFM's semantic focus and the need for pixel-level fidelity, we redesign the VFM-VAE decoder with Multi-Scale Latent Fusion and Progressive Resolution Reconstruction blocks, enabling high-quality reconstruction from spatially coarse VFM features. Furthermore, we provide a comprehensive analysis of representation dynamics during diffusion training, introducing the proposed SE-CKNNA metric as a more precise tool for this diagnosis. This analysis allows us to develop a joint tokenizer-diffusion alignment strategy that dramatically accelerates convergence. Our innovations in tokenizer design and training strategy lead to superior performance and efficiency: our system reaches a gFID (w/o CFG) of 2.20 in merely 80 epochs (a 10x speedup over prior tokenizers). With continued training to 640 epochs, it further attains a gFID (w/o CFG) of 1.62, establishing direct VFM integration as a superior paradigm for LDMs.

Vision Foundation Models (VFMs) have become the cornerstone of modern computer vision, offering robust representations across a wide array of tasks. While recent advances allow these models to handle varying input sizes during training, inference typically remains restricted to a single, fixed scale. This prevalent single-scale paradigm overlooks a fundamental property of visual perception: varying resolutions offer complementary inductive biases, where low-resolution views excel at global semantic recognition and high-resolution views are essential for fine-grained refinement. In this work, we propose Multi-Resolution Fusion (MuRF), a simple yet universally effective strategy to harness this synergy at inference time. Instead of relying on a single view, MuRF constructs a unified representation by processing an image at multiple resolutions through a frozen VFM and fusing the resulting features. The universality of MuRF is its most compelling attribute. It is not tied to a specific architecture, serving instead as a fundamental, training-free enhancement to visual representation. We empirically validate this by applying MuRF to a broad spectrum of critical computer vision tasks across multiple distinct VFM families - primarily DINOv2, but also demonstrating successful generalization to contrastive models like SigLIP2.

Vision foundation models (VFMs) such as DINOv2 and CLIP have achieved impressive results on various downstream tasks, but their limited feature resolution hampers performance in applications requiring pixel-level understanding. Feature upsampling offers a promising direction to address this challenge. In this work, we identify two critical factors for enhancing feature upsampling: the upsampler architecture and the training objective. For the upsampler architecture, we introduce a coordinate-based cross-attention transformer that integrates the high-resolution images with coordinates and low-resolution VFM features to generate sharp, high-quality features. For the training objective, we propose constructing high-resolution pseudo-groundtruth features by leveraging class-agnostic masks and self-distillation. Our approach effectively captures fine-grained details and adapts flexibly to various input and feature resolutions. Through experiments, we demonstrate that our approach significantly outperforms existing feature upsampling techniques across various downstream tasks. Our code is released at https://github.com/andrehuang/loftup.

Vision Foundation Models (VFMs) and Vision-Language Models (VLMs) have gained traction in Domain Generalized Semantic Segmentation (DGSS) due to their strong generalization capabilities. However, existing DGSS methods often rely exclusively on either VFMs or VLMs, overlooking their complementary strengths. VFMs (e.g., DINOv2) excel at capturing fine-grained features, while VLMs (e.g., CLIP) provide robust text alignment but struggle with coarse granularity. Despite their complementary strengths, effectively integrating VFMs and VLMs with attention mechanisms is challenging, as the increased patch tokens complicate long-sequence modeling. To address this, we propose MFuser, a novel Mamba-based fusion framework that efficiently combines the strengths of VFMs and VLMs while maintaining linear scalability in sequence length. MFuser consists of two key components: MVFuser, which acts as a co-adapter to jointly fine-tune the two models by capturing both sequential and spatial dynamics; and MTEnhancer, a hybrid attention-Mamba module that refines text embeddings by incorporating image priors. Our approach achieves precise feature locality and strong text alignment without incurring significant computational overhead. Extensive experiments demonstrate that MFuser significantly outperforms state-of-the-art DGSS methods, achieving 68.20 mIoU on synthetic-to-real and 71.87 mIoU on real-to-real benchmarks. The code is available at https://github.com/devinxzhang/MFuser.

Accurate segmentation of organs and tumors in CT and MRI scans is essential for diagnosis, treatment planning, and disease monitoring. While deep learning has advanced automated segmentation, most models remain task-specific, lacking generalizability across modalities and institutions. Vision foundation models (FMs) pretrained on billion-scale natural images offer powerful and transferable representations. However, adapting them to medical imaging faces two key challenges: (1) the ViT backbone of most foundation models still underperform specialized CNNs on medical image segmentation, and (2) the large domain gap between natural and medical images limits transferability. We introduce MedDINOv3, a simple and effective framework for adapting DINOv3 to medical segmentation. We first revisit plain ViTs and design a simple and effective architecture with multi-scale token aggregation. Then, we perform domain-adaptive pretraining on CT-3M, a curated collection of 3.87M axial CT slices, using a multi-stage DINOv3 recipe to learn robust dense features. MedDINOv3 matches or exceeds state-of-the-art performance across four segmentation benchmarks, demonstrating the potential of vision foundation models as unified backbones for medical image segmentation. The code is available at https://github.com/ricklisz/MedDINOv3.

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly heterogeneous tiles extracted from whole-slide images (WSIs) of real-world patient samples. The performance of these FMs is significantly influenced by the size, diversity, and balance of the pre-training data. However, data selection has been primarily guided by expert knowledge at the WSI level, focusing on factors such as disease classification and tissue types, while largely overlooking the granular details available at the tile level. In this paper, we investigate the potential of unsupervised automatic data curation at the tile-level, taking into account 350 million tiles. Specifically, we apply hierarchical clustering trees to pre-extracted tile embeddings, allowing us to sample balanced datasets uniformly across the embedding space of the pretrained FM. We further identify these datasets are subject to a trade-off between size and balance, potentially compromising the quality of representations learned by FMs, and propose tailored batch sampling strategies to mitigate this effect. We demonstrate the effectiveness of our method through improved performance on a diverse range of clinically relevant downstream tasks.

Vision Foundation Models (VFMs) have demonstrated outstanding performance on numerous downstream tasks. However, due to their inherent representation biases originating from different training paradigms, VFMs exhibit advantages and disadvantages across distinct vision tasks. Although amalgamating the strengths of multiple VFMs for downstream tasks is an intuitive strategy, effectively exploiting these biases remains a significant challenge. In this paper, we propose a novel and versatile "Swiss Army Knife" (SAK) solution, which adaptively distills knowledge from a committee of VFMs to enhance multi-task learning. Unlike existing methods that use a single backbone for knowledge transfer, our approach preserves the unique representation bias of each teacher by collaborating the lightweight Teacher-Specific Adapter Path modules with the Teacher-Agnostic Stem. Through dynamic selection and combination of representations with Mixture-of-Representations Routers, our SAK is capable of synergizing the complementary strengths of multiple VFMs. Extensive experiments show that our SAK remarkably outperforms prior state of the arts in multi-task learning by 10% on the NYUD-v2 benchmark, while also providing a flexible and robust framework that can readily accommodate more advanced model designs.

Vision foundation models (VFMs) have emerged as powerful tools for surgical scene understanding. However, current approaches predominantly rely on unimodal RGB pre-training, overlooking the complex 3D geometry inherent to surgical environments. Although several architectures support multimodal or geometry-aware inputs in general computer vision, the benefits of incorporating depth information in surgical settings remain underexplored. We conduct a large-scale empirical study comparing eight ViT-based VFMs that differ in pre-training domain, learning objective, and input modality (RGB vs. RGB-D). For pre-training, we use a curated dataset of 1.4 million robotic surgical images paired with depth maps generated from an off-the-shelf network. We evaluate these models under both frozen-backbone and end-to-end fine-tuning protocols across eight surgical datasets spanning object detection, segmentation, depth estimation, and pose estimation. Our experiments yield several consistent findings. Models incorporating explicit geometric tokenization, such as MultiMAE, substantially outperform unimodal baselines across all tasks. Notably, geometric-aware pre-training enables remarkable data efficiency: models fine-tuned on just 25% of labeled data consistently surpass RGB-only models trained on the full dataset. Importantly, these gains require no architectural or runtime changes at inference; depth is used only during pre-training, making adoption straightforward. These findings suggest that multimodal pre-training offers a viable path towards building more capable surgical vision systems.

Vision Foundation Models (VFMs) excel in generalization due to large-scale pretraining, but fine-tuning them for Domain Generalized Semantic Segmentation (DGSS) while maintaining this ability remains challenging. Existing approaches either selectively fine-tune parameters or freeze the VFMs and update only the adapters, both of which may underutilize the VFMs' full potential in DGSS tasks. We observe that domain-sensitive parameters in VFMs, arising from task and distribution differences, can hinder generalization. To address this, we propose FisherTune, a robust fine-tuning method guided by the Domain-Related Fisher Information Matrix (DR-FIM). DR-FIM measures parameter sensitivity across tasks and domains, enabling selective updates that preserve generalization and enhance DGSS adaptability. FisherTune incorporates variational inference to stabilize DR-FIM estimation, treating parameters as Gaussian-distributed variables and leveraging pre-trained priors. Extensive experiments show that FisherTune achieves superior cross-domain segmentation while maintaining generalization, outperforming selective-parameter and adapter-based methods.

Computer vision foundation models, such as DINO or OpenCLIP, are trained in a self-supervised manner on large image datasets. Analogously, substantial evidence suggests that the human visual system (HVS) is influenced by the statistical distribution of colors and patterns in the natural world, characteristics also present in the training data of foundation models. The question we address in this paper is whether foundation models trained on natural images mimic some of the low-level characteristics of the human visual system, such as contrast detection, contrast masking, and contrast constancy. Specifically, we designed a protocol comprising nine test types to evaluate the image encoders of 45 foundation and generative models. Our results indicate that some foundation models (e.g., DINO, DINOv2, and OpenCLIP), share some of the characteristics of human vision, but other models show little resemblance. Foundation models tend to show smaller sensitivity to low contrast and rather irregular responses to contrast across frequencies. The foundation models show the best agreement with human data in terms of contrast masking. Our findings suggest that human vision and computer vision may take both similar and different paths when learning to interpret images of the real world. Overall, while differences remain, foundation models trained on vision tasks start to align with low-level human vision, with DINOv2 showing the closest resemblance.

We present Sapiens, a family of models for four fundamental human-centric vision tasks - 2D pose estimation, body-part segmentation, depth estimation, and surface normal prediction. Our models natively support 1K high-resolution inference and are extremely easy to adapt for individual tasks by simply fine-tuning models pretrained on over 300 million in-the-wild human images. We observe that, given the same computational budget, self-supervised pretraining on a curated dataset of human images significantly boosts the performance for a diverse set of human-centric tasks. The resulting models exhibit remarkable generalization to in-the-wild data, even when labeled data is scarce or entirely synthetic. Our simple model design also brings scalability - model performance across tasks improves as we scale the number of parameters from 0.3 to 2 billion. Sapiens consistently surpasses existing baselines across various human-centric benchmarks. We achieve significant improvements over the prior state-of-the-art on Humans-5K (pose) by 7.6 mAP, Humans-2K (part-seg) by 17.1 mIoU, Hi4D (depth) by 22.4% relative RMSE, and THuman2 (normal) by 53.5% relative angular error.

Cloud segmentation is a critical challenge in remote sensing image interpretation, as its accuracy directly impacts the effectiveness of subsequent data processing and analysis. Recently, vision foundation models (VFM) have demonstrated powerful generalization capabilities across various visual tasks. In this paper, we present a parameter-efficient adaptive approach, termed Cloud-Adapter, designed to enhance the accuracy and robustness of cloud segmentation. Our method leverages a VFM pretrained on general domain data, which remains frozen, eliminating the need for additional training. Cloud-Adapter incorporates a lightweight spatial perception module that initially utilizes a convolutional neural network (ConvNet) to extract dense spatial representations. These multi-scale features are then aggregated and serve as contextual inputs to an adapting module, which modulates the frozen transformer layers within the VFM. Experimental results demonstrate that the Cloud-Adapter approach, utilizing only 0.6% of the trainable parameters of the frozen backbone, achieves substantial performance gains. Cloud-Adapter consistently attains state-of-the-art (SOTA) performance across a wide variety of cloud segmentation datasets from multiple satellite sources, sensor series, data processing levels, land cover scenarios, and annotation granularities. We have released the source code and pretrained models at https://github.com/XavierJiezou/Cloud-Adapter to support further research.

Automated visual understanding of our diverse and open world demands computer vision models to generalize well with minimal customization for specific tasks, similar to human vision. Computer vision foundation models, which are trained on diverse, large-scale dataset and can be adapted to a wide range of downstream tasks, are critical for this mission to solve real-world computer vision applications. While existing vision foundation models such as CLIP, ALIGN, and Wu Dao 2.0 focus mainly on mapping images and textual representations to a cross-modal shared representation, we introduce a new computer vision foundation model, Florence, to expand the representations from coarse (scene) to fine (object), from static (images) to dynamic (videos), and from RGB to multiple modalities (caption, depth). By incorporating universal visual-language representations from Web-scale image-text data, our Florence model can be easily adapted for various computer vision tasks, such as classification, retrieval, object detection, VQA, image caption, video retrieval and action recognition. Moreover, Florence demonstrates outstanding performance in many types of transfer learning: fully sampled fine-tuning, linear probing, few-shot transfer and zero-shot transfer for novel images and objects. All of these properties are critical for our vision foundation model to serve general purpose vision tasks. Florence achieves new state-of-the-art results in majority of 44 representative benchmarks, e.g., ImageNet-1K zero-shot classification with top-1 accuracy of 83.74 and the top-5 accuracy of 97.18, 62.4 mAP on COCO fine tuning, 80.36 on VQA, and 87.8 on Kinetics-600.

The integration of deep learning systems into the medical domain has been hindered by the resource-intensive process of data annotation and the inability of these systems to generalize to different data distributions. Foundation models, which are models pre-trained on large datasets, have emerged as a solution to reduce reliance on annotated data and enhance model generalizability and robustness. DINOv2, an open-source foundation model pre-trained with self-supervised learning on 142 million curated natural images, excels in extracting general-purpose visual representations, exhibiting promising capabilities across various vision tasks. Nevertheless, a critical question remains unanswered regarding DINOv2's adaptability to radiological imaging, and the clarity on whether its features are sufficiently general to benefit radiology image analysis is yet to be established. Therefore, this study comprehensively evaluates DINOv2 for radiology, conducting over 100 experiments across diverse modalities (X-ray, CT, and MRI). Tasks include disease classification and organ segmentation on both 2D and 3D images, evaluated under different settings like kNN, few-shot learning, linear-probing, end-to-end fine-tuning, and parameter-efficient fine-tuning, to measure the effectiveness and generalizability of the DINOv2 feature embeddings. Comparative analyses with established medical image analysis models, U-Net and TransUnet for segmentation, and CNN and ViT models pre-trained via supervised, weakly supervised, and self-supervised learning for classification, reveal DINOv2's superior performance in segmentation tasks and competitive results in disease classification. The findings contribute insights to potential avenues for optimizing pre-training strategies for medical imaging and enhancing the broader understanding of DINOv2's role in bridging the gap between natural and radiological image analysis.

Recent vision foundation models (VFMs), typically based on Vision Transformer (ViT), have significantly advanced numerous computer vision tasks. Despite their success in tasks focused solely on RGB images, the potential of VFMs in RGB-depth driving scene parsing remains largely under-explored. In this article, we take one step toward this emerging research area by investigating a feasible technique to fully exploit VFMs for generalizable RGB-depth driving scene parsing. Specifically, we explore the inherent characteristics of RGB and depth data, thereby presenting a Heterogeneous Feature Integration Transformer (HFIT). This network enables the efficient extraction and integration of comprehensive heterogeneous features without re-training ViTs. Relative depth prediction results from VFMs, used as inputs to the HFIT side adapter, overcome the limitations of the dependence on depth maps. Our proposed HFIT demonstrates superior performance compared to all other traditional single-modal and data-fusion scene parsing networks, pre-trained VFMs, and ViT adapters on the Cityscapes and KITTI Semantics datasets. We believe this novel strategy paves the way for future innovations in VFM-based data-fusion techniques for driving scene parsing. Our source code is publicly available at https://mias.group/HFIT.

While Contrastive Language-Image Pre-training (CLIP) has advanced open-vocabulary predictions, its performance on semantic segmentation remains suboptimal. This shortfall primarily stems from its spatial-invariant semantic features and constrained resolution. While previous adaptations addressed spatial invariance semantic by modifying the self-attention in CLIP's image encoder, the issue of limited resolution remains unexplored. Different from previous segment-then-splice methods that segment sub-images via a sliding window and splice the results, we introduce a splice-then-segment paradigm that incorporates Segment-Anything Model (SAM) to tackle the resolution issue since SAM excels at extracting fine-grained semantic correlations from high-resolution images. Specifically, we introduce Trident, a training-free framework that first splices features extracted by CLIP and DINO from sub-images, then leverages SAM's encoder to create a correlation matrix for global aggregation, enabling a broadened receptive field for effective segmentation. Besides, we propose a refinement strategy for CLIP's coarse segmentation outputs by transforming them into prompts for SAM, further enhancing the segmentation performance. Trident achieves a significant improvement in the mIoU across eight benchmarks compared with the current SOTA, increasing from 44.4 to 48.6.Code is available at https://github.com/YuHengsss/Trident.

Executing multiple tasks simultaneously in medical image analysis, including segmentation, classification, detection, and regression, often introduces significant challenges regarding model generalizability and the optimization of shared feature representations. While Vision Foundation Models (VFMs) provide powerful general representations, full fine-tuning on limited medical data is prone to overfitting and incurs high computational costs. Moreover, existing parameter-efficient fine-tuning approaches typically adopt task-agnostic adaptation protocols, overlooking both task-specific mechanisms and the varying sensitivity of model layers during fine-tuning. In this work, we propose Task-Aware Prompting and Selective Layer Fine-Tuning (TAP-SLF), a unified framework for multi-task ultrasound image analysis. TAP-SLF incorporates task-aware soft prompts to encode task-specific priors into the input token sequence and applies LoRA to selected specific top layers of the encoder. This strategy updates only a small fraction of the VFM parameters while keeping the pre-trained backbone frozen. By combining task-aware prompts with selective high-layer fine-tuning, TAP-SLF enables efficient VFM adaptation to diverse medical tasks within a shared backbone. Results on the FMC_UIA 2026 Challenge test set, where TAP-SLF wins fifth place, combined with evaluations on the officially released training dataset using an 8:2 train-test split, demonstrate that task-aware prompting and selective layer tuning are effective strategies for efficient VFM adaptation.

In this work, we aim to develop simple and efficient models for human mesh recovery (HMR) and its predecessor task, human pose estimation (HPE). State-of-the-art HMR methods, such as HMR2.0 and its successors, rely on large, non-hierarchical vision transformers as encoders, which are inherited from the corresponding HPE models like ViTPose. To establish baselines across varying computational budgets, we first construct three lightweight HMR2.0 variants by adapting the corresponding ViTPose models. In addition, we propose leveraging the early stages of hierarchical vision foundation models (VFMs), including Swin Transformer, GroupMixFormer, and VMamba, as encoders. This design is motivated by the observation that intermediate stages of hierarchical VFMs produce feature maps with resolutions comparable to or higher than those of non-hierarchical counterparts. We conduct a comprehensive evaluation of 27 hierarchical-VFM-based HMR and HPE models, demonstrating that using only the first two or three stages achieves performance on par with full-stage models. Moreover, we show that the resulting truncated models exhibit better trade-offs between accuracy and computational efficiency compared to existing lightweight alternatives. The source code is available at https://github.com/nttcom/TruncHierVFM.

Medical foundation models, pre-trained with large-scale clinical data, demonstrate strong performance in diverse clinically relevant applications. RETFound, trained on nearly one million retinal images, exemplifies this approach in applications with retinal images. However, the emergence of increasingly powerful and multifold larger generalist foundation models such as DINOv2 and DINOv3 raises the question of whether domain-specific pre-training remains essential, and if so, what gap persists. To investigate this, we systematically evaluated the adaptability of DINOv2 and DINOv3 in retinal image applications, compared to two specialist RETFound models, RETFound-MAE and RETFound-DINOv2. We assessed performance on ocular disease detection and systemic disease prediction using two adaptation strategies: fine-tuning and linear probing. Data efficiency and adaptation efficiency were further analysed to characterise trade-offs between predictive performance and computational cost. Our results show that although scaling generalist models yields strong adaptability across diverse tasks, RETFound-DINOv2 consistently outperforms these generalist foundation models in ocular-disease detection and oculomics tasks, demonstrating stronger generalisability and data efficiency. These findings suggest that specialist retinal foundation models remain the most effective choice for clinical applications, while the narrowing gap with generalist foundation models suggests that continued data and model scaling can deliver domain-relevant gains and position them as strong foundations for future medical foundation models.

Perceiving visual scenes as objects and background -- like humans do -- Object-Centric Learning (OCL) aggregates image or video feature maps into object-level feature vectors, termed slots. OCL's self-supervision of reconstructing the input from these aggregated slots struggles with complex object textures, thus Vision Foundation Model (VFM) representations are used as the aggregation input and reconstruction target. However, existing methods leverage VFM representations in diverse ways and often fail to fully exploit their potential. In response, we propose a clean architecture -- Vector-Quantized VFMs for OCL (VQ-VFM-OCL, or VVO) -- that unifies mainstream OCL methods. The key to our unification is simple yet effective, just shared quantizing the same VFM representation as the reconstruction target. Through mathematical modeling and statistical verification, we further analyze why VFM representations facilitate OCL aggregation and how their shared quantization as reconstruction targets strengthens OCL supervision. Experiments show that across different VFMs, aggregators and decoders, our VVO consistently outperforms baselines in object discovery and recognition, as well as downstream visual prediction and reasoning. The source code is available in supplemental files.

The landscape of publicly available vision foundation models (VFMs), such as CLIP and Segment Anything Model (SAM), is expanding rapidly. VFMs are endowed with distinct capabilities stemming from their pre-training objectives. For instance, CLIP excels in semantic understanding, while SAM specializes in spatial understanding for segmentation. In this work, we introduce a simple recipe to efficiently merge VFMs into a unified model that assimilates their expertise. Our proposed method integrates multi-task learning, continual learning techniques, and teacher-student distillation. This strategy entails significantly less computational cost compared to traditional multi-task training from scratch. Additionally, it only demands a small fraction of the pre-training datasets that were initially used to train individual models. By applying our method to SAM and CLIP, we derive SAM-CLIP: a unified model that amalgamates the strengths of SAM and CLIP into a single backbone, making it apt for edge device applications. We show that SAM-CLIP learns richer visual representations, equipped with both localization and semantic features, suitable for a broad range of vision tasks. SAM-CLIP obtains improved performance on several head probing tasks when compared with SAM and CLIP. We further show that SAM-CLIP not only retains the foundational strengths of its precursor models but also introduces synergistic functionalities, most notably in zero-shot semantic segmentation, where SAM-CLIP establishes new state-of-the-art results on 5 benchmarks. It outperforms previous models that are specifically designed for this task by a large margin, including +6.8% and +5.9% mean IoU improvement on Pascal-VOC and COCO-Stuff datasets, respectively.

Vision-based robot policy learning, which maps visual inputs to actions, necessitates a holistic understanding of diverse visual tasks beyond single-task needs like classification or segmentation. Inspired by this, we introduce Theia, a vision foundation model for robot learning that distills multiple off-the-shelf vision foundation models trained on varied vision tasks. Theia's rich visual representations encode diverse visual knowledge, enhancing downstream robot learning. Extensive experiments demonstrate that Theia outperforms its teacher models and prior robot learning models using less training data and smaller model sizes. Additionally, we quantify the quality of pre-trained visual representations and hypothesize that higher entropy in feature norm distributions leads to improved robot learning performance. Code and models are available at https://github.com/bdaiinstitute/theia.

The exponential growth of large language models (LLMs) has opened up numerous possibilities for multi-modal AGI systems. However, the progress in vision and vision-language foundation models, which are also critical elements of multi-modal AGI, has not kept pace with LLMs. In this work, we design a large-scale vision-language foundation model (InternVL), which scales up the vision foundation model to 6 billion parameters and progressively aligns it with the large language model, using web-scale image-text data from various sources. This model can be broadly applied to and achieve state-of-the-art performance on visual perception tasks such as image-level or pixel-level recognition, vision-language tasks such as zero-shot image/video classification, zero-shot image/video-text retrieval, and link with LLMs to create multi-modal dialogue systems. We hope that our research could contribute to the development of multi-modal large models. Code and models are available at https://github.com/OpenGVLab/InternVL.

Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in pathology image analysis. However, their improvements in cell instance segmentation remain limited. A key challenge arises from the tokenization process in ViTs, which substantially reduces the spatial resolution of input images, leading to suboptimal segmentation quality, especially for small and densely packed cells. To address this problem, we propose CellVTA (Cell Vision Transformer with Adapter), a novel method that improves the performance of vision foundation models for cell instance segmentation by incorporating a CNN-based adapter module. This adapter extracts high-resolution spatial information from input images and injects it into the ViT through a cross-attention mechanism. Our method preserves the core architecture of ViT, ensuring seamless integration with pretrained foundation models. Extensive experiments show that CellVTA achieves 0.538 mPQ on the CoNIC dataset and 0.506 mPQ on the PanNuke dataset, which significantly outperforms the state-of-the-art cell segmentation methods. Ablation studies confirm the superiority of our approach over other fine-tuning strategies, including decoder-only fine-tuning and full fine-tuning. Our code and models are publicly available at https://github.com/JieZheng-ShanghaiTech/CellVTA.

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer diagnosis from dermoscopic images, they struggle to meet the complex, multimodal requirements of clinical practice. Here, we introduce PanDerm, a multimodal dermatology foundation model pretrained through self-supervised learning on over 2 million real-world skin disease images from 11 clinical institutions across 4 imaging modalities. We evaluated PanDerm on 28 diverse benchmarks, including skin cancer screening, risk stratification, differential diagnosis of common and rare skin conditions, lesion segmentation, longitudinal monitoring, and metastasis prediction and prognosis. PanDerm achieved state-of-the-art performance across all evaluated tasks, often outperforming existing models when using only 10% of labeled data. We conducted three reader studies to assess PanDerm's potential clinical utility. PanDerm outperformed clinicians by 10.2% in early-stage melanoma detection through longitudinal analysis, improved clinicians' skin cancer diagnostic accuracy by 11% on dermoscopy images, and enhanced non-dermatologist healthcare providers' differential diagnosis by 16.5% across 128 skin conditions on clinical photographs. These results demonstrate PanDerm's potential to improve patient care across diverse clinical scenarios and serve as a model for developing multimodal foundation models in other medical specialties, potentially accelerating the integration of AI support in healthcare. The code can be found at https://github.com/SiyuanYan1/PanDerm.

Forecasting from partial observations is central to world modeling. Many recent methods represent the world through images, and reduce forecasting to stochastic video generation. Although such methods excel at realism and visual fidelity, predicting pixels is computationally intensive and not directly useful in many applications, as it requires translating RGB into signals useful for decision making. An alternative approach uses features from vision foundation models (VFMs) as world representations, performing deterministic regression to predict future world states. These features can be directly translated into actionable signals such as semantic segmentation and depth, while remaining computationally efficient. However, deterministic regression averages over multiple plausible futures, undermining forecast accuracy by failing to capture uncertainty. To address this crucial limitation, we introduce a generative forecaster that performs autoregressive flow matching in VFM feature space. Our key insight is that generative modeling in this space requires encoding VFM features into a compact latent space suitable for diffusion. We show that this latent space preserves information more effectively than previously used PCA-based alternatives, both for forecasting and other applications, such as image generation. Our latent predictions can be easily decoded into multiple useful and interpretable output modalities: semantic segmentation, depth, surface normals, and even RGB. With matched architecture and compute, our method produces sharper and more accurate predictions than regression across all modalities. Our results suggest that stochastic conditional generation of VFM features offers a promising and scalable foundation for future world models.

Soccer understanding has recently garnered growing research interest due to its domain-specific complexity and unique challenges. Unlike prior works that typically rely on isolated, task-specific expert models, this work aims to propose a unified model to handle diverse soccer visual understanding tasks, ranging from fine-grained perception (e.g., athlete detection) to semantic reasoning (e.g., event classification). Specifically, our contributions are threefold: (i) we present SoccerMaster, the first soccer-specific vision foundation model that unifies diverse understanding tasks within a single framework via supervised multi-task pretraining; (ii) we develop an automated data curation pipeline to generate scalable spatial annotations, and integrate them with various existing soccer video datasets to construct SoccerFactory, a comprehensive pretraining data resource; and (iii) we conduct extensive evaluations demonstrating that SoccerMaster consistently outperforms task-specific expert models across diverse downstream tasks, highlighting its breadth and superiority. The data, code, and model will be publicly available.

Accurate plant counting provides valuable information for agriculture such as crop yield prediction, plant density assessment, and phenotype quantification. Vision-based approaches are currently the mainstream solution. Prior art typically uses a detection or a regression model to count a specific plant. However, plants have biodiversity, and new cultivars are increasingly bred each year. It is almost impossible to exhaust and build all species-dependent counting models. Inspired by class-agnostic counting (CAC) in computer vision, we argue that it is time to rethink the problem formulation of plant counting, from what plants to count to how to count plants. In contrast to most daily objects with spatial and temporal invariance, plants are dynamic, changing with time and space. Their non-rigid structure often leads to worse performance than counting rigid instances like heads and cars such that current CAC and open-world detection models are suboptimal to count plants. In this work, we inherit the vein of the TasselNet plant counting model and introduce a new extension, TasselNetV4, shifting from species-specific counting to cross-species counting. TasselNetV4 marries the local counting idea of TasselNet with the extract-and-match paradigm in CAC. It builds upon a plain vision transformer and incorporates novel multi-branch box-aware local counters used to enhance cross-scale robustness. Two challenging datasets, PAC-105 and PAC-Somalia, are harvested. Extensive experiments against state-of-the-art CAC models show that TasselNetV4 achieves not only superior counting performance but also high efficiency.Our results indicate that TasselNetV4 emerges to be a vision foundation model for cross-scene, cross-scale, and cross-species plant counting.

To tackle the prevalence of pseudo changes, the scarcity of labeled samples, and the difficulty of cross-domain generalization in multi-temporal and multi-source remote sensing imagery, we propose PeftCD, a change detection framework built upon Vision Foundation Models (VFMs) with Parameter-Efficient Fine-Tuning (PEFT). At its core, PeftCD employs a weight-sharing Siamese encoder derived from a VFM, into which LoRA and Adapter modules are seamlessly integrated. This design enables highly efficient task adaptation by training only a minimal set of additional parameters. To fully unlock the potential of VFMs, we investigate two leading backbones: the Segment Anything Model v2 (SAM2), renowned for its strong segmentation priors, and DINOv3, a state-of-the-art self-supervised representation learner. The framework is complemented by a deliberately lightweight decoder, ensuring the focus remains on the powerful feature representations from the backbones. Extensive experiments demonstrate that PeftCD achieves state-of-the-art performance across multiple public datasets, including SYSU-CD (IoU 73.81%), WHUCD (92.05%), MSRSCD (64.07%), MLCD (76.89%), CDD (97.01%), S2Looking (52.25%) and LEVIR-CD (85.62%), with notably precise boundary delineation and strong suppression of pseudo-changes. In summary, PeftCD presents an optimal balance of accuracy, efficiency, and generalization. It offers a powerful and scalable paradigm for adapting large-scale VFMs to real-world remote sensing change detection applications. The code and pretrained models will be released at https://github.com/dyzy41/PeftCD.

This paper proposes Pix2Next, a novel image-to-image translation framework designed to address the challenge of generating high-quality Near-Infrared (NIR) images from RGB inputs. Our approach leverages a state-of-the-art Vision Foundation Model (VFM) within an encoder-decoder architecture, incorporating cross-attention mechanisms to enhance feature integration. This design captures detailed global representations and preserves essential spectral characteristics, treating RGB-to-NIR translation as more than a simple domain transfer problem. A multi-scale PatchGAN discriminator ensures realistic image generation at various detail levels, while carefully designed loss functions couple global context understanding with local feature preservation. We performed experiments on the RANUS dataset to demonstrate Pix2Next's advantages in quantitative metrics and visual quality, improving the FID score by 34.81% compared to existing methods. Furthermore, we demonstrate the practical utility of Pix2Next by showing improved performance on a downstream object detection task using generated NIR data to augment limited real NIR datasets. The proposed approach enables the scaling up of NIR datasets without additional data acquisition or annotation efforts, potentially accelerating advancements in NIR-based computer vision applications.

Large-scale vision foundation models have made significant progress in visual tasks on natural images, with vision transformers being the primary choice due to their good scalability and representation ability. However, large-scale models in remote sensing (RS) have not yet been sufficiently explored. In this paper, we resort to plain vision transformers with about 100 million parameters and make the first attempt to propose large vision models tailored to RS tasks and investigate how such large models perform. To handle the large sizes and objects of arbitrary orientations in RS images, we propose a new rotated varied-size window attention to replace the original full attention in transformers, which can significantly reduce the computational cost and memory footprint while learning better object representation by extracting rich context from the generated diverse windows. Experiments on detection tasks show the superiority of our model over all state-of-the-art models, achieving 81.24% mAP on the DOTA-V1.0 dataset. The results of our models on downstream classification and segmentation tasks also show competitive performance compared to existing advanced methods. Further experiments show the advantages of our models in terms of computational complexity and data efficiency in transferring.

Pre-trained Vision Foundation Models (VFMs) provide strong visual representations for a wide range of applications. In this paper, we continually pre-train prevailing VFMs in a multimodal manner such that they can effortlessly process visual inputs of varying sizes and produce visual representations that are more aligned with language representations, regardless of their original pre-training process. To this end, we introduce CoMP, a carefully designed multimodal pre-training pipeline. CoMP uses a Continual Rotary Position Embedding to support native resolution continual pre-training, and an Alignment Loss between visual and textual features through language prototypes to align multimodal representations. By three-stage training, our VFMs achieve remarkable improvements not only in multimodal understanding but also in other downstream tasks such as classification and segmentation. Remarkably, CoMP-SigLIP achieves scores of 66.7 on ChartQA and 75.9 on DocVQA with a 0.5B LLM, while maintaining an 87.4% accuracy on ImageNet-1K and a 49.5 mIoU on ADE20K under frozen chunk evaluation.

Active computer vision promises efficient, biologically plausible perception through sequential, localized glimpses, but lacks scalable general-purpose architectures and pretraining pipelines. As a result, Active-Vision Foundation Models (AVFMs) have remained unexplored. We introduce CanViT, the first task- and policy-agnostic AVFM. CanViT uses scene-relative RoPE to bind a retinotopic Vision Transformer backbone and a spatiotopic scene-wide latent workspace, the canvas. Efficient interaction with this high-capacity working memory is supported by Canvas Attention, a novel asymmetric cross-attention mechanism. We decouple thinking (backbone-level) and memory (canvas-level), eliminating canvas-side self-attention and fully-connected layers to achieve low-latency sequential inference and scalability to large scenes. We propose a label-free active vision pretraining scheme, policy-agnostic passive-to-active dense latent distillation: reconstructing scene-wide DINOv3 embeddings from sequences of low-resolution glimpses with randomized locations, zoom levels, and lengths. We pretrain CanViT-B from a random initialization on 13.2 million ImageNet-21k scenes -- an order of magnitude more than previous active models -- and 1 billion random glimpses, in 166 hours on a single H100. On ADE20K segmentation, a frozen CanViT-B achieves 38.5% mIoU in a single low-resolution glimpse, outperforming the best active model's 27.6% with 19.5x fewer inference FLOPs and no fine-tuning, as well as its FLOP- or input-matched DINOv3 teacher. Given additional glimpses, CanViT-B reaches 45.9% ADE20K mIoU. On ImageNet-1k classification, CanViT-B reaches 81.2% top-1 accuracy with frozen teacher probes. CanViT generalizes to longer rollouts, larger scenes, and new policies. Our work closes the wide gap between passive and active vision on semantic segmentation and demonstrates the potential of AVFMs as a new research axis.

Zero-shot anomaly detection aims to detect and localise abnormal regions in the image without access to any in-domain training images. While recent approaches leverage vision-language models (VLMs), such as CLIP, to transfer high-level concept knowledge, methods based on purely vision foundation models (VFMs), like DINOv2, have lagged behind in performance. We argue that this gap stems from two practical issues: (i) limited diversity in existing auxiliary anomaly detection datasets and (ii) overly shallow VFM adaptation strategies. To address both challenges, we propose AnomalyVFM, a general and effective framework that turns any pretrained VFM into a strong zero-shot anomaly detector. Our approach combines a robust three-stage synthetic dataset generation scheme with a parameter-efficient adaptation mechanism, utilising low-rank feature adapters and a confidence-weighted pixel loss. Together, these components enable modern VFMs to substantially outperform current state-of-the-art methods. More specifically, with RADIO as a backbone, AnomalyVFM achieves an average image-level AUROC of 94.1% across 9 diverse datasets, surpassing previous methods by significant 3.3 percentage points. Project Page: https://maticfuc.github.io/anomaly_vfm/

Recent advancements in vision foundation models (VFMs) have opened up new possibilities for versatile and efficient visual perception. In this work, we introduce Seal, a novel framework that harnesses VFMs for segmenting diverse automotive point cloud sequences. Seal exhibits three appealing properties: i) Scalability: VFMs are directly distilled into point clouds, eliminating the need for annotations in either 2D or 3D during pretraining. ii) Consistency: Spatial and temporal relationships are enforced at both the camera-to-LiDAR and point-to-segment stages, facilitating cross-modal representation learning. iii) Generalizability: Seal enables knowledge transfer in an off-the-shelf manner to downstream tasks involving diverse point clouds, including those from real/synthetic, low/high-resolution, large/small-scale, and clean/corrupted datasets. Extensive experiments conducted on eleven different point cloud datasets showcase the effectiveness and superiority of Seal. Notably, Seal achieves a remarkable 45.0% mIoU on nuScenes after linear probing, surpassing random initialization by 36.9% mIoU and outperforming prior arts by 6.1% mIoU. Moreover, Seal demonstrates significant performance gains over existing methods across 20 different few-shot fine-tuning tasks on all eleven tested point cloud datasets.

Self-supervised image backbones can be used to address complex 2D tasks (e.g., semantic segmentation, object discovery) very efficiently and with little or no downstream supervision. Ideally, 3D backbones for lidar should be able to inherit these properties after distillation of these powerful 2D features. The most recent methods for image-to-lidar distillation on autonomous driving data show promising results, obtained thanks to distillation methods that keep improving. Yet, we still notice a large performance gap when measuring the quality of distilled and fully supervised features by linear probing. In this work, instead of focusing only on the distillation method, we study the effect of three pillars for distillation: the 3D backbone, the pretrained 2D backbones, and the pretraining dataset. In particular, thanks to our scalable distillation method named ScaLR, we show that scaling the 2D and 3D backbones and pretraining on diverse datasets leads to a substantial improvement of the feature quality. This allows us to significantly reduce the gap between the quality of distilled and fully-supervised 3D features, and to improve the robustness of the pretrained backbones to domain gaps and perturbations.

The recently proposed SparseFormer architecture provides an alternative approach to visual understanding by utilizing a significantly lower number of visual tokens via adjusting RoIs, greatly reducing computational costs while still achieving promising performance. However, training SparseFormers from scratch is still expensive, and scaling up the number of parameters can be challenging. In this paper, we propose to bootstrap SparseFormers from ViT-based vision foundation models in a simple and efficient way. Since the majority of SparseFormer blocks are the standard transformer ones, we can inherit weights from large-scale pre-trained vision transformers and freeze them as much as possible. Therefore, we only need to train the SparseFormer-specific lightweight focusing transformer to adjust token RoIs and fine-tune a few early pre-trained blocks to align the final token representation. In such a way, we can bootstrap SparseFormer architectures from various large-scale pre-trained models (e.g., IN-21K pre-trained AugRegs or CLIPs) using a rather smaller amount of training samples (e.g., IN-1K) and without labels or captions within just a few hours. As a result, the bootstrapped unimodal SparseFormer (from AugReg-ViT-L/16-384) can reach 84.9% accuracy on IN-1K with only 49 tokens, and the multimodal SparseFormer from CLIPs also demonstrates notable zero-shot performance with highly reduced computational cost without seeing any caption during the bootstrapping procedure. In addition, CLIP-bootstrapped SparseFormers, which align the output space with language without seeing a word, can serve as efficient vision encoders in multimodal large language models. Code will be publicly available at https://github.com/showlab/sparseformer

Vision-driven field monitoring is central to digital agriculture, yet models built on general-domain pretrained backbones often fail to generalize across tasks, owing to the interaction of fine, variable canopy structures with fluctuating field conditions. We present FoMo4Wheat, one of the first crop-domain vision foundation model pretrained with self-supervision on ImAg4Wheat, the largest and most diverse wheat image dataset to date (2.5 million high-resolution images collected over a decade at 30 global sites, spanning >2,000 genotypes and >500 environmental conditions). This wheat-specific pretraining yields representations that are robust for wheat and transferable to other crops and weeds. Across ten in-field vision tasks at canopy and organ levels, FoMo4Wheat models consistently outperform state-of-the-art models pretrained on general-domain dataset. These results demonstrate the value of crop-specific foundation models for reliable in-field perception and chart a path toward a universal crop foundation model with cross-species and cross-task capabilities. FoMo4Wheat models and the ImAg4Wheat dataset are publicly available online: https://github.com/PheniX-Lab/FoMo4Wheat and https://huggingface.co/PheniX-Lab/FoMo4Wheat. The demonstration website is: https://fomo4wheat.phenix-lab.com/.

The superior representation capability of pre-trained vision foundation models (VFMs) has been harnessed for enhancing latent diffusion models (LDMs). These approaches inject the rich semantics from high-dimensional VFM representations (e.g., DINOv3) into LDMs at different phases, resulting in accelerated learning and better generation performance. However, the high-dimensionality of VFM representations may also lead to Information Overload, particularly when the VFM features exceed the size of the original image for decoding. To address this issue while preserving the utility of VFM features, we propose RePack (Representation Packing), a simple yet effective framework for improving Diffusion Transformers (DiTs). RePack transforms the VFM representation into a more compact, decoder-friendly representation by projecting onto low-dimensional manifolds. We find that RePack can effectively filter out non-semantic noise while preserving the core structural information needed for high-fidelity reconstruction. Experimental results show that RePack significantly accelerates DiT convergence and outperforms recent methods that directly inject raw VFM features into the decoder for image reconstruction. On DiT-XL/2, RePack achieves an FID of 3.66 in only 64 epochs, which is 35% faster than the state-of-the-art method. This demonstrates that RePack successfully extracts the core semantics of VFM representations while bypassing their high-dimensionality side effects.

Sparse observations and coarse-resolution climate models limit effective regional decision-making, underscoring the need for robust downscaling. However, existing AI methods struggle with generalization across variables and geographies and are constrained by the quadratic complexity of Vision Transformer (ViT) self-attention. We introduce ORBIT-2, a scalable foundation model for global, hyper-resolution climate downscaling. ORBIT-2 incorporates two key innovations: (1) Residual Slim ViT (Reslim), a lightweight architecture with residual learning and Bayesian regularization for efficient, robust prediction; and (2) TILES, a tile-wise sequence scaling algorithm that reduces self-attention complexity from quadratic to linear, enabling long-sequence processing and massive parallelism. ORBIT-2 scales to 10 billion parameters across 65,536 GPUs, achieving up to 4.1 exaFLOPS sustained throughput and 74--98% strong scaling efficiency. It supports downscaling to 0.9 km global resolution and processes sequences up to 4.2 billion tokens. On 7 km resolution benchmarks, ORBIT-2 achieves high accuracy with R^2 scores in the range of 0.98--0.99 against observational data.

Compared to the great progress of large-scale vision transformers (ViTs) in recent years, large-scale models based on convolutional neural networks (CNNs) are still in an early state. This work presents a new large-scale CNN-based foundation model, termed InternImage, which can obtain the gain from increasing parameters and training data like ViTs. Different from the recent CNNs that focus on large dense kernels, InternImage takes deformable convolution as the core operator, so that our model not only has the large effective receptive field required for downstream tasks such as detection and segmentation, but also has the adaptive spatial aggregation conditioned by input and task information. As a result, the proposed InternImage reduces the strict inductive bias of traditional CNNs and makes it possible to learn stronger and more robust patterns with large-scale parameters from massive data like ViTs. The effectiveness of our model is proven on challenging benchmarks including ImageNet, COCO, and ADE20K. It is worth mentioning that InternImage-H achieved a new record 65.4 mAP on COCO test-dev and 62.9 mIoU on ADE20K, outperforming current leading CNNs and ViTs. The code will be released at https://github.com/OpenGVLab/InternImage.

Recent advancements in large language models have sparked interest in their extraordinary and near-superhuman capabilities, leading researchers to explore methods for evaluating and optimizing these abilities, which is called superalignment. In this context, our paper delves into the realm of vision foundation models, focusing on the concept of weak-to-strong generalization, which involves using a weaker model to supervise a stronger one, aiming to enhance the latter's capabilities beyond the former's limits. We introduce a novel and adaptively adjustable loss function for weak-to-strong supervision. Our comprehensive experiments span various scenarios, including few-shot learning, transfer learning, noisy label learning, and common knowledge distillation settings. The results are striking: our approach not only exceeds the performance benchmarks set by strong-to-strong generalization but also surpasses the outcomes of fine-tuning strong models with whole datasets. This compelling evidence underscores the significant potential of weak-to-strong generalization, showcasing its capability to substantially elevate the performance of vision foundation models. The code is available at https://github.com/ggjy/vision_weak_to_strong.

Real-time object detection has achieved substantial progress through meticulously designed architectures and optimization strategies. However, the pursuit of high-speed inference via lightweight network designs often leads to degraded feature representation, which hinders further performance improvements and practical on-device deployment. In this paper, we propose a cost-effective and highly adaptable distillation framework that harnesses the rapidly evolving capabilities of Vision Foundation Models (VFMs) to enhance lightweight object detectors. Given the significant architectural and learning objective disparities between VFMs and resource-constrained detectors, achieving stable and task-aligned semantic transfer is challenging. To address this, on one hand, we introduce a Deep Semantic Injector (DSI) module that facilitates the integration of high-level representations from VFMs into the deep layers of the detector. On the other hand, we devise a Gradient-guided Adaptive Modulation (GAM) strategy, which dynamically adjusts the intensity of semantic transfer based on gradient norm ratios. Without increasing deployment and inference overhead, our approach painlessly delivers striking and consistent performance gains across diverse DETR-based models, underscoring its practical utility for real-time detection. Our new model family, RT-DETRv4, achieves state-of-the-art results on COCO, attaining AP scores of 49.7/53.5/55.4/57.0 at corresponding speeds of 273/169/124/78 FPS.

Knowledge distillation (KD) has been widely applied in semantic segmentation to compress large models, but conventional approaches primarily preserve in-domain accuracy while neglecting out-of-domain generalization, which is essential under distribution shifts. This limitation becomes more severe with the emergence of vision foundation models (VFMs): although VFMs exhibit strong robustness on unseen data, distilling them with conventional KD often compromises this ability. We propose Generalizable Knowledge Distillation (GKD), a multi-stage framework that explicitly enhances generalization. GKD decouples representation learning from task learning. In the first stage, the student acquires domain-agnostic representations through selective feature distillation, and in the second stage, these representations are frozen for task adaptation, thereby mitigating overfitting to visible domains. To further support transfer, we introduce a query-based soft distillation mechanism, where student features act as queries to teacher representations to selectively retrieve transferable spatial knowledge from VFMs. Extensive experiments on five domain generalization benchmarks demonstrate that GKD consistently outperforms existing KD methods, achieving average gains of +1.9% in foundation-to-foundation (F2F) and +10.6% in foundation-to-local (F2L) distillation. The code will be available at https://github.com/Younger-hua/GKD.

Recently, feature upsampling has gained increasing attention owing to its effectiveness in enhancing vision foundation models (VFMs) for pixel-level understanding tasks. Existing methods typically rely on high-resolution features from the same foundation model to achieve upsampling via self-reconstruction. However, relying solely on intra-model features forces the upsampler to overfit to the source model's inherent location misalignment and high-norm artifacts. To address this fundamental limitation, we propose DiveUp, a novel framework that breaks away from single-model dependency by introducing multi-VFM relational guidance. Instead of naive feature fusion, DiveUp leverages diverse VFMs as a panel of experts, utilizing their structural consensus to regularize the upsampler's learning process, effectively preventing the propagation of inaccurate spatial structures from the source model. To reconcile the unaligned feature spaces across different VFMs, we propose a universal relational feature representation, formulated as a local center-of-mass (COM) field, that extracts intrinsic geometric structures, enabling seamless cross-model interaction. Furthermore, we introduce a spikiness-aware selection strategy that evaluates the spatial reliability of each VFM, effectively filtering out high-norm artifacts to aggregate guidance from only the most reliable expert at each local region. DiveUp is a unified, encoder-agnostic framework; a jointly-trained model can universally upsample features from diverse VFMs without requiring per-model retraining. Extensive experiments demonstrate that DiveUp achieves state-of-the-art performance across various downstream dense prediction tasks, validating the efficacy of multi-expert relational guidance. Our code and models are available at: https://github.com/Xiaoqiong-Liu/DiveUp

Agglomerative models have recently emerged as a powerful approach to training vision foundation models, leveraging multi-teacher distillation from existing models such as CLIP, DINO, and SAM. This strategy enables the efficient creation of robust models, combining the strengths of individual teachers while significantly reducing computational and resource demands. In this paper, we thoroughly analyze state-of-the-art agglomerative models, identifying critical challenges including resolution mode shifts, teacher imbalance, idiosyncratic teacher artifacts, and an excessive number of output tokens. To address these issues, we propose several novel solutions: multi-resolution training, mosaic augmentation, and improved balancing of teacher loss functions. Specifically, in the context of Vision Language Models, we introduce a token compression technique to maintain high-resolution information within a fixed token count. We release our top-performing models, available in multiple scales (-B, -L, -H, and -g), alongside inference code and pretrained weights.

Vision-Language-Action (VLA) models have recently emerged as a promising paradigm for robotic manipulation, in which reliable action prediction critically depends on accurately interpreting and integrating visual observations conditioned on language instructions. Although recent works have sought to enhance the visual capabilities of VLA models, most approaches treat the LLM backbone as a black box, providing limited insight into how visual information is grounded into action generation. Therefore, we perform a systematic analysis of multiple VLA models across different action-generation paradigms and observe that sensitivity to visual tokens progressively decreases in deeper layers during action generation. Motivated by this observation, we propose DeepVision-VLA, built on a Vision-Language Mixture-of-Transformers (VL-MoT) framework. This framework enables shared attention between the vision foundation model and the VLA backbone, injecting multi-level visual features from the vision expert into deeper layers of the VLA backbone to enhance visual representations for precise and complex manipulation. In addition, we introduce Action-Guided Visual Pruning (AGVP), which leverages shallow-layer attention to prune irrelevant visual tokens while preserving task-relevant ones, reinforcing critical visual cues for manipulation with minimal computational overhead. DeepVision-VLA outperforms prior state-of-the-art methods by 9.0\% and 7.5\% on simulated and real-world tasks, respectively, providing new insights for the design of visually enhanced VLA models.

Visual imitation learning frameworks allow robots to learn manipulation skills from expert demonstrations. While existing approaches mainly focus on policy design, they often neglect the structure and capacity of visual encoders, limiting spatial understanding and generalization. Inspired by biological vision systems, which rely on both visual and proprioceptive cues for robust control, we propose VGGT-DP, a visuomotor policy framework that integrates geometric priors from a pretrained 3D perception model with proprioceptive feedback. We adopt the Visual Geometry Grounded Transformer (VGGT) as the visual encoder and introduce a proprioception-guided visual learning strategy to align perception with internal robot states, improving spatial grounding and closed-loop control. To reduce inference latency, we design a frame-wise token reuse mechanism that compacts multi-view tokens into an efficient spatial representation. We further apply random token pruning to enhance policy robustness and reduce overfitting. Experiments on challenging MetaWorld tasks show that VGGT-DP significantly outperforms strong baselines such as DP and DP3, particularly in precision-critical and long-horizon scenarios.

This paper proposes novel methods to enhance the performance of monocular 3D object detection models by leveraging the generalized feature extraction capabilities of a vision foundation model. Unlike traditional CNN-based approaches, which often suffer from inaccurate depth estimation and rely on multi-stage object detection pipelines, this study employs a Vision Transformer (ViT)-based foundation model as the backbone, which excels at capturing global features for depth estimation. It integrates a detection transformer (DETR) architecture to improve both depth estimation and object detection performance in a one-stage manner. Specifically, a hierarchical feature fusion block is introduced to extract richer visual features from the foundation model, further enhancing feature extraction capabilities. Depth estimation accuracy is further improved by incorporating a relative depth estimation model trained on large-scale data and fine-tuning it through transfer learning. Additionally, the use of queries in the transformer's decoder, which consider reference points and the dimensions of 2D bounding boxes, enhances recognition performance. The proposed model outperforms recent state-of-the-art methods, as demonstrated through quantitative and qualitative evaluations on the KITTI 3D benchmark and a custom dataset collected from high-elevation racing environments. Code is available at https://github.com/JihyeokKim/MonoDINO-DETR.

Vision transformers (ViTs) have emerged as a significant area of focus, particularly for their capacity to be jointly trained with large language models and to serve as robust vision foundation models. Yet, the development of trustworthy explanation methods for ViTs has lagged, particularly in the context of post-hoc interpretations of ViT predictions. Existing sub-image selection approaches, such as feature-attribution and conceptual models, fall short in this regard. This paper proposes five desiderata for explaining ViTs -- faithfulness, stability, sparsity, multi-level structure, and parsimony -- and demonstrates the inadequacy of current methods in meeting these criteria comprehensively. We introduce a variational Bayesian explanation framework, dubbed ProbAbilistic Concept Explainers (PACE), which models the distributions of patch embeddings to provide trustworthy post-hoc conceptual explanations. Our qualitative analysis reveals the distributions of patch-level concepts, elucidating the effectiveness of ViTs by modeling the joint distribution of patch embeddings and ViT's predictions. Moreover, these patch-level explanations bridge the gap between image-level and dataset-level explanations, thus completing the multi-level structure of PACE. Through extensive experiments on both synthetic and real-world datasets, we demonstrate that PACE surpasses state-of-the-art methods in terms of the defined desiderata.

Object navigation (ObjectNav) requires an agent to navigate through unseen environments to find queried objects. Many previous methods attempted to solve this task by relying on supervised or reinforcement learning, where they are trained on limited household datasets with close-set objects. However, two key challenges are unsolved: understanding free-form natural language instructions that demand open-set objects, and generalizing to new environments in a zero-shot manner. Aiming to solve the two challenges, in this paper, we propose OpenFMNav, an Open-set Foundation Model based framework for zero-shot object Navigation. We first unleash the reasoning abilities of large language models (LLMs) to extract proposed objects from natural language instructions that meet the user's demand. We then leverage the generalizability of large vision language models (VLMs) to actively discover and detect candidate objects from the scene, building a Versatile Semantic Score Map (VSSM). Then, by conducting common sense reasoning on VSSM, our method can perform effective language-guided exploration and exploitation of the scene and finally reach the goal. By leveraging the reasoning and generalizing abilities of foundation models, our method can understand free-form human instructions and perform effective open-set zero-shot navigation in diverse environments. Extensive experiments on the HM3D ObjectNav benchmark show that our method surpasses all the strong baselines on all metrics, proving our method's effectiveness. Furthermore, we perform real robot demonstrations to validate our method's open-set-ness and generalizability to real-world environments.

Parameter-efficient fine-tuning (PEFT) that was initially developed for exploiting pre-trained large language models has recently emerged as an effective approach to perform transfer learning on computer vision tasks. However, the effectiveness of PEFT on medical vision foundation models is still unclear and remains to be explored. As a proof of concept, we conducted a detailed empirical study on applying PEFT to chest radiography foundation models. Specifically, we delved into LoRA, a representative PEFT method, and compared it against full-parameter fine-tuning (FFT) on two self-supervised radiography foundation models across three well-established chest radiograph datasets. Our results showed that LoRA outperformed FFT in 13 out of 18 transfer learning tasks by at most 2.9% using fewer than 1% tunable parameters. Combining LoRA with foundation models, we set up new state-of-the-art on a range of data-efficient learning tasks, such as an AUROC score of 80.6% using 1% labeled data on NIH ChestX-ray14. We hope this study can evoke more attention from the community in the use of PEFT for transfer learning on medical imaging tasks. Code and models are available at https://github.com/RL4M/MED-PEFT.

The recent explosive interest in the reasoning capabilities of large language models, such as DeepSeek-R1, has demonstrated remarkable success through reinforcement learning-based fine-tuning frameworks, exemplified by methods like Group Relative Policy Optimization (GRPO). However, such reasoning abilities remain underexplored and notably absent in vision foundation models, including representation models like the DINO series. In this work, we propose DINO-R1, the first such attempt to incentivize visual in-context reasoning capabilities of vision foundation models using reinforcement learning. Specifically, DINO-R1 introduces Group Relative Query Optimization (GRQO), a novel reinforcement-style training strategy explicitly designed for query-based representation models, which computes query-level rewards based on group-normalized alignment quality. We also apply KL-regularization to stabilize the objectness distribution to reduce the training instability. This joint optimization enables dense and expressive supervision across queries while mitigating overfitting and distributional drift. Building upon Grounding-DINO, we train a series of DINO-R1 family models that integrate a visual prompt encoder and a visual-guided query selection mechanism. Extensive experiments on COCO, LVIS, and ODinW demonstrate that DINO-R1 significantly outperforms supervised fine-tuning baselines, achieving strong generalization in both open-vocabulary and closed-set visual prompting scenarios.

Modern monocular 3D reconstruction methods and vision-language models (VLMs) demonstrate impressive results on standard benchmarks, yet recent works cast doubt on their true understanding of geometric properties. We introduce GOQ, a comprehensive benchmark specifically designed to evaluate the geometric reasoning capabilities of vision and vision-language foundation models. GIQ comprises synthetic and real-world images and corresponding 3D meshes of diverse polyhedra covering varying levels of complexity and symmetry, from Platonic, Archimedean, Johnson, and Catalan solids to stellations and compound shapes. Through systematic experiments involving monocular 3D reconstruction, 3D symmetry detection, mental rotation tests, and zero-shot shape classification tasks, we reveal significant shortcomings in current models. State-of-the-art reconstruction algorithms trained on extensive 3D datasets struggle to reconstruct even basic geometric Platonic solids accurately. Next, although foundation models may be shown via linear and non-linear probing to capture specific 3D symmetry elements, they falter significantly in tasks requiring detailed geometric differentiation, such as mental rotation. Moreover, advanced vision-language assistants such as ChatGPT, Gemini and Claud exhibit remarkably low accuracy in interpreting basic shape properties such as face geometry, convexity, and compound structures of complex polyhedra. GIQ is publicly available at toomanymatts.github.io/giq-benchmark/, providing a structured platform to benchmark critical gaps in geometric intelligence and facilitate future progress in robust, geometry-aware representation learning.

We propose a conceptually simple and lightweight framework for improving the robustness of vision models through the combination of knowledge distillation and data augmentation. We address the conjecture that larger models do not make for better teachers by showing strong gains in out-of-distribution robustness when distilling from pretrained foundation models. Following this finding, we propose Discrete Adversarial Distillation (DAD), which leverages a robust teacher to generate adversarial examples and a VQGAN to discretize them, creating more informative samples than standard data augmentation techniques. We provide a theoretical framework for the use of a robust teacher in the knowledge distillation with data augmentation setting and demonstrate strong gains in out-of-distribution robustness and clean accuracy across different student architectures. Notably, our method adds minor computational overhead compared to similar techniques and can be easily combined with other data augmentations for further improvements.

Prompt engineering is a technique that involves augmenting a large pre-trained model with task-specific hints, known as prompts, to adapt the model to new tasks. Prompts can be created manually as natural language instructions or generated automatically as either natural language instructions or vector representations. Prompt engineering enables the ability to perform predictions based solely on prompts without updating model parameters, and the easier application of large pre-trained models in real-world tasks. In past years, Prompt engineering has been well-studied in natural language processing. Recently, it has also been intensively studied in vision-language modeling. However, there is currently a lack of a systematic overview of prompt engineering on pre-trained vision-language models. This paper aims to provide a comprehensive survey of cutting-edge research in prompt engineering on three types of vision-language models: multimodal-to-text generation models (e.g. Flamingo), image-text matching models (e.g. CLIP), and text-to-image generation models (e.g. Stable Diffusion). For each type of model, a brief model summary, prompting methods, prompting-based applications, and the corresponding responsibility and integrity issues are summarized and discussed. Furthermore, the commonalities and differences between prompting on vision-language models, language models, and vision models are also discussed. The challenges, future directions, and research opportunities are summarized to foster future research on this topic.

Detecting glass regions is a challenging task due to the inherent ambiguity in their transparency and reflective characteristics. Current solutions in this field remain rooted in conventional deep learning paradigms, requiring the construction of annotated datasets and the design of network architectures. However, the evident drawback with these mainstream solutions lies in the time-consuming and labor-intensive process of curating datasets, alongside the increasing complexity of model structures. In this paper, we propose to address these issues by fully harnessing the capabilities of two existing vision foundation models (VFMs): Stable Diffusion and Segment Anything Model (SAM). Firstly, we construct a Synthetic but photorealistic large-scale Glass Surface Detection dataset, dubbed S-GSD, without any labour cost via Stable Diffusion. This dataset consists of four different scales, consisting of 168k images totally with precise masks. Besides, based on the powerful segmentation ability of SAM, we devise a simple Glass surface sEgMentor named GEM, which follows the simple query-based encoder-decoder architecture. Comprehensive experiments are conducted on the large-scale glass segmentation dataset GSD-S. Our GEM establishes a new state-of-the-art performance with the help of these two VFMs, surpassing the best-reported method GlassSemNet with an IoU improvement of 2.1%. Additionally, extensive experiments demonstrate that our synthetic dataset S-GSD exhibits remarkable performance in zero-shot and transfer learning settings. Codes, datasets and models are publicly available at: https://github.com/isbrycee/GEM

Estimating the 6D pose of objects unseen during training is highly desirable yet challenging. Zero-shot object 6D pose estimation methods address this challenge by leveraging additional task-specific supervision provided by large-scale, photo-realistic synthetic datasets. However, their performance heavily depends on the quality and diversity of rendered data and they require extensive training. In this work, we show how to tackle the same task but without training on specific data. We propose FreeZe, a novel solution that harnesses the capabilities of pre-trained geometric and vision foundation models. FreeZe leverages 3D geometric descriptors learned from unrelated 3D point clouds and 2D visual features learned from web-scale 2D images to generate discriminative 3D point-level descriptors. We then estimate the 6D pose of unseen objects by 3D registration based on RANSAC. We also introduce a novel algorithm to solve ambiguous cases due to geometrically symmetric objects that is based on visual features. We comprehensively evaluate FreeZe across the seven core datasets of the BOP Benchmark, which include over a hundred 3D objects and 20,000 images captured in various scenarios. FreeZe consistently outperforms all state-of-the-art approaches, including competitors extensively trained on synthetic 6D pose estimation data. Code will be publicly available at https://andreacaraffa.github.io/freeze.

Multiple works have emerged to push the boundaries on multi-modal large language models (MLLMs) towards pixel-level understanding. Such approaches have shown strong performance on benchmarks for referring expression segmentation and grounded conversation generation. The current trend in pixel-level MLLMs is to train with pixel-level grounding supervision on large-scale labelled data. However, we show that such MLLMs when evaluated on recent challenging vision centric benchmarks, exhibit a weak ability in visual question answering. Surprisingly, some of these methods even downgrade the grounding ability of MLLMs that were never trained with such supervision. In this work, we propose two novel challenging benchmarks and show that MLLMs without pixel-level grounding supervision can outperform the state of the art in such tasks when evaluating both the pixel-level grounding and visual question answering. We propose simple baselines to extract the grounding information that can be plugged into any MLLM, which we call as PixFoundation. More importantly, we study the research question of "When does grounding emerge in MLLMs that are not trained with pixel-level grounding supervision?" We show that grounding can coincide with object parts or location/appearance information. Code repository is at https://github.com/MSiam/PixFoundation/.

Recent advances in video generation have enabled the synthesis of videos with strong temporal consistency and impressive visual quality, marking a crucial step toward vision foundation models. To evaluate these video generation models, existing benchmarks primarily focus on factors related to visual perception and understanding, like visual aesthetics, instruction adherence, and temporal coherence. However, the rule-based reasoning capabilities of video generation models remain largely unexplored. Although recent studies have carried out preliminary explorations into whether video models can serve as zero-shot learners, they still lack a fine-grained decomposition of reasoning capabilities and a comprehensive evaluation protocol. To address this gap, we introduce RULER-Bench, a benchmark designed to evaluate the reasoning ability of video generation models from the perspective of cognitive rules. Built upon two fundamental paradigms: text-to-video and image-to-video, RULER-Bench covers 40 representative tasks spanning six rule categories with 622 high-quality annotated instances. For the evaluation of each generated video, we construct a checklist covering four metrics and leverage GPT-o3 to assign scores to each question, achieving 85% alignment with human judgements. Extensive experiments show that the state-of-the-art model achieves only 48.87% on the rule coherence metric, highlighting significant room for improvement in the reasoning capability of next-level video models. We expect that the insight obtained from RULER-Bench will facilitate further development of reasoning-aware video generation, advancing video generation models toward vision foundation intelligence.

In this paper, we first assess and harness various Vision Foundation Models (VFMs) in the context of Domain Generalized Semantic Segmentation (DGSS). Driven by the motivation that Leveraging Stronger pre-trained models and Fewer trainable parameters for Superior generalizability, we introduce a robust fine-tuning approach, namely Rein, to parameter-efficiently harness VFMs for DGSS. Built upon a set of trainable tokens, each linked to distinct instances, Rein precisely refines and forwards the feature maps from each layer to the next layer within the backbone. This process produces diverse refinements for different categories within a single image. With fewer trainable parameters, Rein efficiently fine-tunes VFMs for DGSS tasks, surprisingly surpassing full parameter fine-tuning. Extensive experiments across various settings demonstrate that Rein significantly outperforms state-of-the-art methods. Remarkably, with just an extra 1% of trainable parameters within the frozen backbone, Rein achieves a mIoU of 78.4% on the Cityscapes, without accessing any real urban-scene datasets.Code is available at https://github.com/w1oves/Rein.git.

Vision foundation models like DINOv2 demonstrate remarkable potential in medical imaging despite their origin in natural image domains. However, their design inherently works best for uni-modal image analysis, limiting their effectiveness for multi-modal imaging tasks that are common in many medical fields, such as neurology and oncology. While supervised models perform well in this setting, they fail to leverage unlabeled datasets and struggle with missing modalities, a frequent challenge in clinical settings. To bridge these gaps, we introduce MM-DINOv2, a novel and efficient framework that adapts the pre-trained vision foundation model DINOv2 for multi-modal medical imaging. Our approach incorporates multi-modal patch embeddings, enabling vision foundation models to effectively process multi-modal imaging data. To address missing modalities, we employ full-modality masking, which encourages the model to learn robust cross-modality relationships. Furthermore, we leverage semi-supervised learning to harness large unlabeled datasets, enhancing both the accuracy and reliability of medical predictions. Applied to glioma subtype classification from multi-sequence brain MRI, our method achieves a Matthews Correlation Coefficient (MCC) of 0.6 on an external test set, surpassing state-of-the-art supervised approaches by +11.1%. Our work establishes a scalable and robust solution for multi-modal medical imaging tasks, leveraging powerful vision foundation models pre-trained on natural images while addressing real-world clinical challenges such as missing data and limited annotations.

Vision foundation models (VFMs) trained on large-scale image datasets provide high-quality features that have significantly advanced 2D visual recognition. However, their potential in 3D vision remains largely untapped, despite the common availability of 2D images alongside 3D point cloud datasets. While significant research has been dedicated to 2D-3D fusion, recent state-of-the-art 3D methods predominantly focus on 3D data, leaving the integration of VFMs into 3D models underexplored. In this work, we challenge this trend by introducing DITR, a simple yet effective approach that extracts 2D foundation model features, projects them to 3D, and finally injects them into a 3D point cloud segmentation model. DITR achieves state-of-the-art results on both indoor and outdoor 3D semantic segmentation benchmarks. To enable the use of VFMs even when images are unavailable during inference, we further propose to distill 2D foundation models into a 3D backbone as a pretraining task. By initializing the 3D backbone with knowledge distilled from 2D VFMs, we create a strong basis for downstream 3D segmentation tasks, ultimately boosting performance across various datasets.

Pretrained vision foundation models (VFMs) advance robotic learning via rich visual representations, yet individual VFMs typically excel only in specific domains, limiting generality across tasks. Distilling multiple VFMs into a unified representation for policy can mitigate this limitation but often yields inflexible task-specific feature selection and requires costly full re-training to incorporate robot-domain knowledge. We propose VER, a Vision Expert transformer for Robot learning. During pretraining, VER distills multiple VFMs into a vision expert library. It then fine-tunes only a lightweight routing network (fewer than 0.4% of parameters) to dynamically select task-relevant experts from the pretrained library for downstream robot tasks. We further introduce Patchwise Expert Routing with Curriculum Top-K Annealing to improve both flexibility and precision of dynamic expert selection. Moreover, VER supports parameter-efficient finetuning for scalable expert utilization and adaptive robot-domain knowledge integration. Across 17 diverse robotic tasks and multiple policy heads, VER achieves state-of-the-art performance. We find that VER reduces large-norm outliers in task-irrelevant regions (e.g., background) and concentrates on task-critical regions. Visualizations and codes can be found in https://yixiaowang7.github.io/ver_page/.

Recent vision foundation models can extract universal representations and show impressive abilities in various tasks. However, their application on object detection is largely overlooked, especially without fine-tuning them. In this work, we show that frozen foundation models can be a versatile feature enhancer, even though they are not pre-trained for object detection. Specifically, we explore directly transferring the high-level image understanding of foundation models to detectors in the following two ways. First, the class token in foundation models provides an in-depth understanding of the complex scene, which facilitates decoding object queries in the detector's decoder by providing a compact context. Additionally, the patch tokens in foundation models can enrich the features in the detector's encoder by providing semantic details. Utilizing frozen foundation models as plug-and-play modules rather than the commonly used backbone can significantly enhance the detector's performance while preventing the problems caused by the architecture discrepancy between the detector's backbone and the foundation model. With such a novel paradigm, we boost the SOTA query-based detector DINO from 49.0% AP to 51.9% AP (+2.9% AP) and further to 53.8% AP (+4.8% AP) by integrating one or two foundation models respectively, on the COCO validation set after training for 12 epochs with R50 as the detector's backbone.

Pathology foundation models substantially advanced the possibilities in computational pathology -- yet tradeoffs in terms of performance, robustness, and computational requirements remained, which limited their clinical deployment. In this report, we present Atlas 2, Atlas 2-B, and Atlas 2-S, three pathology vision foundation models which bridge these shortcomings by showing state-of-the-art performance in prediction performance, robustness, and resource efficiency in a comprehensive evaluation across eighty public benchmarks. Our models were trained on the largest pathology foundation model dataset to date comprising 5.5 million histopathology whole slide images, collected from three medical institutions Charité - Universtätsmedizin Berlin, LMU Munich, and Mayo Clinic.

Early detection, accurate segmentation, classification and tracking of polyps during colonoscopy are critical for preventing colorectal cancer. Many existing deep-learning-based methods for analyzing colonoscopic videos either require task-specific fine-tuning, lack tracking capabilities, or rely on domain-specific pre-training. In this paper, we introduce PolypSegTrack, a novel foundation model that jointly addresses polyp detection, segmentation, classification and unsupervised tracking in colonoscopic videos. Our approach leverages a novel conditional mask loss, enabling flexible training across datasets with either pixel-level segmentation masks or bounding box annotations, allowing us to bypass task-specific fine-tuning. Our unsupervised tracking module reliably associates polyp instances across frames using object queries, without relying on any heuristics. We leverage a robust vision foundation model backbone that is pre-trained unsupervisedly on natural images, thereby removing the need for domain-specific pre-training. Extensive experiments on multiple polyp benchmarks demonstrate that our method significantly outperforms existing state-of-the-art approaches in detection, segmentation, classification, and tracking.

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models or adapting them to a new condition is costly due to the need for (manually) labeled data. The emergence of vision foundation models, especially Segment Anything, offers a path to universal segmentation for medical images, overcoming these issues. Here, we study how to improve Segment Anything for medical images by comparing different finetuning strategies on a large and diverse dataset. We evaluate the finetuned models on a wide range of interactive and (automatic) semantic segmentation tasks. We find that the performance can be clearly improved for interactive segmentation. However, semantic segmentation does not benefit from pretraining on medical images. Our best model, MedicoSAM, is publicly available at https://github.com/computational-cell-analytics/medico-sam. We show that it is compatible with existing tools for data annotation and believe that it will be of great practical value.

Accurate prostate cancer diagnosis remains challenging. Even when using MRI, radiologists exhibit low specificity and significant inter-observer variability, leading to potential delays or inaccuracies in identifying clinically significant cancers. This leads to numerous unnecessary biopsies and risks of missing clinically significant cancers. Here we present prostate vision contrastive network (ProViCNet), prostate organ-specific vision foundation models for Magnetic Resonance Imaging (MRI) and Trans-Rectal Ultrasound imaging (TRUS) for comprehensive cancer detection. ProViCNet was trained and validated using 4,401 patients across six institutions, as a prostate cancer detection model on radiology images relying on patch-level contrastive learning guided by biopsy confirmed radiologist annotations. ProViCNet demonstrated consistent performance across multiple internal and external validation cohorts with area under the receiver operating curve values ranging from 0.875 to 0.966, significantly outperforming radiologists in the reader study (0.907 versus 0.805, p<0.001) for mpMRI, while achieving 0.670 to 0.740 for TRUS. We also integrated ProViCNet with standard PSA to develop a virtual screening test, and we showed that we can maintain the high sensitivity for detecting clinically significant cancers while more than doubling specificity from 15% to 38% (p<0.001), thereby substantially reducing unnecessary biopsies. These findings highlight that ProViCNet's potential for enhancing prostate cancer diagnosis accuracy and reduce unnecessary biopsies, thereby optimizing diagnostic pathways.

Text and vision foundation models can perform many tasks in a zero-shot setting, a desirable property that enables these systems to be applied in general and low-resource settings. There has been far less work, however, on the zero-shot abilities of ASR foundation models, with these systems typically fine-tuned to specific tasks or constrained to applications that match their training criterion and data annotation. In this work we investigate the ability of Whisper and MMS, ASR foundation models trained primarily for speech recognition, to perform zero-shot audio classification. We use simple template-based text prompts at the decoder and use the resulting decoding probabilities to generate zero-shot predictions. Without training the model on extra data or adding any new parameters, we demonstrate that Whisper shows promising zero-shot classification performance on a range of 8 audio-classification datasets, outperforming the accuracy of existing state-of-the-art zero-shot baselines by an average of 9%. One important step to unlock the emergent ability is debiasing, where a simple unsupervised reweighting method of the class probabilities yields consistent significant performance gains. We further show that performance increases with model size, implying that as ASR foundation models scale up, they may exhibit improved zero-shot performance.