Daily Papers

The field of medical diagnosis has undergone a significant transformation with the advent of large language models (LLMs), yet the challenges of interpretability within these models remain largely unaddressed. This study introduces Chain-of-Diagnosis (CoD) to enhance the interpretability of LLM-based medical diagnostics. CoD transforms the diagnostic process into a diagnostic chain that mirrors a physician's thought process, providing a transparent reasoning pathway. Additionally, CoD outputs the disease confidence distribution to ensure transparency in decision-making. This interpretability makes model diagnostics controllable and aids in identifying critical symptoms for inquiry through the entropy reduction of confidences. With CoD, we developed DiagnosisGPT, capable of diagnosing 9604 diseases. Experimental results demonstrate that DiagnosisGPT outperforms other LLMs on diagnostic benchmarks. Moreover, DiagnosisGPT provides interpretability while ensuring controllability in diagnostic rigor.

With the rapid development of Multi-modal Large Language Models (MLLMs), a number of diagnostic benchmarks have recently emerged to evaluate the comprehension capabilities of these models. However, most benchmarks predominantly assess spatial understanding in the static image tasks, while overlooking temporal understanding in the dynamic video tasks. To alleviate this issue, we introduce a comprehensive Multi-modal Video understanding Benchmark, namely MVBench, which covers 20 challenging video tasks that cannot be effectively solved with a single frame. Specifically, we first introduce a novel static-to-dynamic method to define these temporal-related tasks. By transforming various static tasks into dynamic ones, we enable the systematic generation of video tasks that require a broad spectrum of temporal skills, ranging from perception to cognition. Then, guided by the task definition, we automatically convert public video annotations into multiple-choice QA to evaluate each task. On one hand, such a distinct paradigm allows us to build MVBench efficiently, without much manual intervention. On the other hand, it guarantees evaluation fairness with ground-truth video annotations, avoiding the biased scoring of LLMs. Moreover, we further develop a robust video MLLM baseline, i.e., VideoChat2, by progressive multi-modal training with diverse instruction-tuning data. The extensive results on our MVBench reveal that, the existing MLLMs are far from satisfactory in temporal understanding, while our VideoChat2 largely surpasses these leading models by over 15% on MVBench. All models and data are available at https://github.com/OpenGVLab/Ask-Anything.

Language models have shown promising performance on the task of translating natural language questions into SQL queries (Text-to-SQL). However, most of the state-of-the-art (SOTA) approaches rely on powerful yet closed-source large language models (LLMs), such as ChatGPT and GPT-4, which may have the limitations of unclear model architectures, data privacy risks, and expensive inference overheads. To address the limitations, we introduce CodeS, a series of pre-trained language models with parameters ranging from 1B to 15B, specifically designed for the text-to-SQL task. CodeS is a fully open-source language model, which achieves superior accuracy with much smaller parameter sizes. This paper studies the research challenges in building CodeS. To enhance the SQL generation abilities of CodeS, we adopt an incremental pre-training approach using a specifically curated SQL-centric corpus. Based on this, we address the challenges of schema linking and rapid domain adaptation through strategic prompt construction and a bi-directional data augmentation technique. We conduct comprehensive evaluations on multiple datasets, including the widely used Spider benchmark, the newly released BIRD benchmark, robustness-diagnostic benchmarks such as Spider-DK, Spider-Syn, Spider-Realistic, and Dr.Spider, as well as two real-world datasets created for financial and academic applications. The experimental results show that our CodeS achieves new SOTA accuracy and robustness on nearly all challenging text-to-SQL benchmarks.

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome information overload and reduce the cognitive burden so fewer medical errors and cognitive biases are introduced during patient care. One major type of medical error is diagnostic error due to systematic or predictable errors in judgment that rely on heuristics. The potential for clinical natural language processing (cNLP) to model diagnostic reasoning in humans with forward reasoning from data to diagnosis and potentially reduce the cognitive burden and medical error has not been investigated. Existing tasks to advance the science in cNLP have largely focused on information extraction and named entity recognition through classification tasks. We introduce a novel suite of tasks coined as Diagnostic Reasoning Benchmarks, DR.BENCH, as a new benchmark for developing and evaluating cNLP models with clinical diagnostic reasoning ability. The suite includes six tasks from ten publicly available datasets addressing clinical text understanding, medical knowledge reasoning, and diagnosis generation. DR.BENCH is the first clinical suite of tasks designed to be a natural language generation framework to evaluate pre-trained language models. Experiments with state-of-the-art pre-trained generative language models using large general domain models and models that were continually trained on a medical corpus demonstrate opportunities for improvement when evaluated in DR. BENCH. We share DR. BENCH as a publicly available GitLab repository with a systematic approach to load and evaluate models for the cNLP community.

Reasoning benchmarks have played a crucial role in the progress of language models. Yet rigorous evaluation remains a significant challenge as static question-answer pairs provide only a snapshot of performance, compressing complex behavior into a single accuracy metric. This limitation is especially true in complex, rule-bound domains such as law, where existing benchmarks are costly to build and ill suited for isolating specific failure modes. To address this, we introduce OpenExempt, a framework and benchmark for diagnostic evaluation of legal reasoning. The OpenExempt Framework uses expert-crafted symbolic representations of U.S. Bankruptcy Code statutes to dynamically generate a large space of natural language reasoning tasks and their machine-computable solutions on demand. This gives users fine-grained control over task complexity and scope, allowing individual reasoning skills to be probed in isolation. Using this system, we construct the OpenExempt Benchmark, a diagnostic benchmark for legal reasoning with 9,765 samples across nine evaluation suites designed to carefully probe model capabilities. Experiments on 13 diverse language models reveal sharp performance cliffs that emerge only under longer reasoning paths and in the presence of obfuscating statements. We release the framework and benchmark publicly to support research aimed at understanding and improving the next generation of reasoning systems.

Many Swedish benchmarks are translated US-centric benchmarks, and therefore not suitable for testing knowledge that is particularly relevant, or even specific, to Sweden. We therefore introduce a manually written question-answering benchmark specifically targeted to Sweden-related personalities and events, many of which receive very limited coverage in international media. Our annotators drew inspiration from a popular radio program featuring public figures from culture and media, as well as major sports events in Sweden. The dataset can be used to measure factual recall across models of varying sizes and degrees of Swedish coverage, and allows to probe cross-lingual factual consistency as to contains English translations. Using the dataset, we find that smaller models with stronger Swedish coverage perform comparably to a three times larger multilingual model in recalling Sweden-related facts. We also observe that continued pre-training on Swedish generally improves factual knowledge but also leads to forgetting of a part of the previously known information. These results demonstrate the dataset's potential as a diagnostic tool for studying language adaptation and knowledge retention in multilingual models and during language adaptation.

Although large multimodal models (LMMs) have demonstrated remarkable capabilities in visual scene interpretation and reasoning, their capacity for complex and precise 3-dimensional spatial reasoning remains uncertain. Existing benchmarks focus predominantly on 2D spatial understanding and lack a framework to comprehensively evaluate 6D spatial reasoning across varying complexities. To address this limitation, we present PulseCheck457, a scalable and unbiased synthetic dataset designed with 4 key capability for spatial reasoning: multi-object recognition, 2D location, 3D location, and 3D orientation. We develop a cascading evaluation structure, constructing 7 question types across 5 difficulty levels that range from basic single object recognition to our new proposed complex 6D spatial reasoning tasks. We evaluated various large multimodal models (LMMs) on PulseCheck457, observing a general decline in performance as task complexity increases, particularly in 3D reasoning and 6D spatial tasks. To quantify these challenges, we introduce the Relative Performance Dropping Rate (RPDR), highlighting key weaknesses in 3D reasoning capabilities. Leveraging the unbiased attribute design of our dataset, we also uncover prediction biases across different attributes, with similar patterns observed in real-world image settings.

When building artificial intelligence systems that can reason and answer questions about visual data, we need diagnostic tests to analyze our progress and discover shortcomings. Existing benchmarks for visual question answering can help, but have strong biases that models can exploit to correctly answer questions without reasoning. They also conflate multiple sources of error, making it hard to pinpoint model weaknesses. We present a diagnostic dataset that tests a range of visual reasoning abilities. It contains minimal biases and has detailed annotations describing the kind of reasoning each question requires. We use this dataset to analyze a variety of modern visual reasoning systems, providing novel insights into their abilities and limitations.

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis requires both the outcome and the reasoning process to be accurate. Currently, widely used medical benchmarks like MedQA and MMLU assess only accuracy in the final answer, overlooking the quality and faithfulness of the clinical reasoning process. To address this limitation, we introduce MedCaseReasoning, the first open-access dataset for evaluating LLMs on their ability to align with clinician-authored diagnostic reasoning. The dataset includes 14,489 diagnostic question-and-answer cases, each paired with detailed reasoning statements derived from open-access medical case reports. We evaluate state-of-the-art reasoning LLMs on MedCaseReasoning and find significant shortcomings in their diagnoses and reasoning: for instance, the top-performing open-source model, DeepSeek-R1, achieves only 48% 10-shot diagnostic accuracy and mentions only 64% of the clinician reasoning statements (recall). However, we demonstrate that fine-tuning LLMs on the reasoning traces derived from MedCaseReasoning significantly improves diagnostic accuracy and clinical reasoning recall by an average relative gain of 29% and 41%, respectively. The open-source dataset, code, and models are available at https://github.com/kevinwu23/Stanford-MedCaseReasoning.

Recent advances in generative foundational models, often termed "world models," have propelled interest in applying them to critical tasks like robotic planning and autonomous system training. For reliable deployment, these models must exhibit high physical fidelity, accurately simulating real-world dynamics. Existing physics-based video benchmarks, however, suffer from entanglement, where a single test simultaneously evaluates multiple physical laws and concepts, fundamentally limiting their diagnostic capability. We introduce WorldBench, a novel video-based benchmark specifically designed for concept-specific, disentangled evaluation, allowing us to rigorously isolate and assess understanding of a single physical concept or law at a time. To make WorldBench comprehensive, we design benchmarks at two different levels: 1) an evaluation of intuitive physical understanding with concepts such as object permanence or scale/perspective, and 2) an evaluation of low-level physical constants and material properties such as friction coefficients or fluid viscosity. When SOTA video-based world models are evaluated on WorldBench, we find specific patterns of failure in particular physics concepts, with all tested models lacking the physical consistency required to generate reliable real-world interactions. Through its concept-specific evaluation, WorldBench offers a more nuanced and scalable framework for rigorously evaluating the physical reasoning capabilities of video generation and world models, paving the way for more robust and generalizable world-model-driven learning.

We propose a novel multimodal video benchmark - the Perception Test - to evaluate the perception and reasoning skills of pre-trained multimodal models (e.g. Flamingo, BEiT-3, or GPT-4). Compared to existing benchmarks that focus on computational tasks (e.g. classification, detection or tracking), the Perception Test focuses on skills (Memory, Abstraction, Physics, Semantics) and types of reasoning (descriptive, explanatory, predictive, counterfactual) across video, audio, and text modalities, to provide a comprehensive and efficient evaluation tool. The benchmark probes pre-trained models for their transfer capabilities, in a zero-shot / few-shot or limited finetuning regime. For these purposes, the Perception Test introduces 11.6k real-world videos, 23s average length, designed to show perceptually interesting situations, filmed by around 100 participants worldwide. The videos are densely annotated with six types of labels (multiple-choice and grounded video question-answers, object and point tracks, temporal action and sound segments), enabling both language and non-language evaluations. The fine-tuning and validation splits of the benchmark are publicly available (CC-BY license), in addition to a challenge server with a held-out test split. Human baseline results compared to state-of-the-art video QA models show a significant gap in performance (91.4% vs 43.6%), suggesting that there is significant room for improvement in multimodal video understanding. Dataset, baselines code, and challenge server are available at https://github.com/deepmind/perception_test

We introduce MentalBench, a benchmark for evaluating psychiatric diagnostic decision-making in large language models (LLMs). Existing mental health benchmarks largely rely on social media data, limiting their ability to assess DSM-grounded diagnostic judgments. At the core of MentalBench is MentalKG, a psychiatrist-built and validated knowledge graph encoding DSM-5 diagnostic criteria and differential diagnostic rules for 23 psychiatric disorders. Using MentalKG as a golden-standard logical backbone, we generate 24,750 synthetic clinical cases that systematically vary in information completeness and diagnostic complexity, enabling low-noise and interpretable evaluation. Our experiments show that while state-of-the-art LLMs perform well on structured queries probing DSM-5 knowledge, they struggle to calibrate confidence in diagnostic decision-making when distinguishing between clinically overlapping disorders. These findings reveal evaluation gaps not captured by existing benchmarks.

The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable their safe and effective deployment in real-world healthcare settings, it is urgently necessary to benchmark the diagnostic capabilities of current models systematically. Given the limitations of existing medical benchmarks in evaluating advanced diagnostic reasoning, we present DiagnosisArena, a comprehensive and challenging benchmark designed to rigorously assess professional-level diagnostic competence. DiagnosisArena consists of 1,113 pairs of segmented patient cases and corresponding diagnoses, spanning 28 medical specialties, deriving from clinical case reports published in 10 top-tier medical journals. The benchmark is developed through a meticulous construction pipeline, involving multiple rounds of screening and review by both AI systems and human experts, with thorough checks conducted to prevent data leakage. Our study reveals that even the most advanced reasoning models, o3-mini, o1, and DeepSeek-R1, achieve only 45.82%, 31.09%, and 17.79% accuracy, respectively. This finding highlights a significant generalization bottleneck in current large language models when faced with clinical diagnostic reasoning challenges. Through DiagnosisArena, we aim to drive further advancements in AIs diagnostic reasoning capabilities, enabling more effective solutions for real-world clinical diagnostic challenges. We provide the benchmark and evaluation tools for further research and development https://github.com/SPIRAL-MED/DiagnosisArena.

Tool-augmented large language models (LLMs) are rapidly being integrated into real-world applications. Due to the lack of benchmarks, the community still needs to fully understand the hallucination issues within these models. To address this challenge, we introduce a comprehensive diagnostic benchmark, ToolBH. Specifically, we assess the LLM's hallucinations through two perspectives: depth and breadth. In terms of depth, we propose a multi-level diagnostic process, including (1) solvability detection, (2) solution planning, and (3) missing-tool analysis. For breadth, we consider three scenarios based on the characteristics of the toolset: missing necessary tools, potential tools, and limited functionality tools. Furthermore, we developed seven tasks and collected 700 evaluation samples through multiple rounds of manual annotation. The results show the significant challenges presented by the ToolBH benchmark. The current advanced models Gemini-1.5-Pro and GPT-4o only achieve a total score of 45.3 and 37.0, respectively, on a scale of 100. In this benchmark, larger model parameters do not guarantee better performance; the training data and response strategies also play a crucial role in tool-enhanced LLM scenarios. Our diagnostic analysis indicates that the primary reason for model errors lies in assessing task solvability. Additionally, open-weight models suffer from performance drops with verbose replies, whereas proprietary models excel with longer reasoning.

We present a Japanese domain-specific language model for the pharmaceutical field, developed through continual pretraining on 2 billion Japanese pharmaceutical tokens and 8 billion English biomedical tokens. To enable rigorous evaluation, we introduce three new benchmarks: YakugakuQA, based on national pharmacist licensing exams; NayoseQA, which tests cross-lingual synonym and terminology normalization; and SogoCheck, a novel task designed to assess consistency reasoning between paired statements. We evaluate our model against both open-source medical LLMs and commercial models, including GPT-4o. Results show that our domain-specific model outperforms existing open models and achieves competitive performance with commercial ones, particularly on terminology-heavy and knowledge-based tasks. Interestingly, even GPT-4o performs poorly on SogoCheck, suggesting that cross-sentence consistency reasoning remains an open challenge. Our benchmark suite offers a broader diagnostic lens for pharmaceutical NLP, covering factual recall, lexical variation, and logical consistency. This work demonstrates the feasibility of building practical, secure, and cost-effective language models for Japanese domain-specific applications, and provides reusable evaluation resources for future research in pharmaceutical and healthcare NLP. Our model, codes, and datasets are released at https://github.com/EQUES-Inc/pharma-LLM-eval.

The ability to perceive how objects change over time is a crucial ingredient in human intelligence. However, current benchmarks cannot faithfully reflect the temporal understanding abilities of video-language models (VidLMs) due to the existence of static visual shortcuts. To remedy this issue, we present VITATECS, a diagnostic VIdeo-Text dAtaset for the evaluation of TEmporal Concept underStanding. Specifically, we first introduce a fine-grained taxonomy of temporal concepts in natural language in order to diagnose the capability of VidLMs to comprehend different temporal aspects. Furthermore, to disentangle the correlation between static and temporal information, we generate counterfactual video descriptions that differ from the original one only in the specified temporal aspect. We employ a semi-automatic data collection framework using large language models and human-in-the-loop annotation to obtain high-quality counterfactual descriptions efficiently. Evaluation of representative video-language understanding models confirms their deficiency in temporal understanding, revealing the need for greater emphasis on the temporal elements in video-language research.

Despite the successes of recent developments in visual AI, different shortcomings still exist; from missing exact logical reasoning, to abstract generalization abilities, to understanding complex and noisy scenes. Unfortunately, existing benchmarks, were not designed to capture more than a few of these aspects. Whereas deep learning datasets focus on visually complex data but simple visual reasoning tasks, inductive logic datasets involve complex logical learning tasks, however, lack the visual component. To address this, we propose the visual logical learning dataset, V-LoL, that seamlessly combines visual and logical challenges. Notably, we introduce the first instantiation of V-LoL, V-LoL-Trains, -- a visual rendition of a classic benchmark in symbolic AI, the Michalski train problem. By incorporating intricate visual scenes and flexible logical reasoning tasks within a versatile framework, V-LoL-Trains provides a platform for investigating a wide range of visual logical learning challenges. We evaluate a variety of AI systems including traditional symbolic AI, neural AI, as well as neuro-symbolic AI. Our evaluations demonstrate that even state-of-the-art AI faces difficulties in dealing with visual logical learning challenges, highlighting unique advantages and limitations specific to each methodology. Overall, V-LoL opens up new avenues for understanding and enhancing current abilities in visual logical learning for AI systems.

Audio-visual understanding is a rapidly evolving field that seeks to integrate and interpret information from both auditory and visual modalities. Despite recent advances in multi-modal learning, existing benchmarks often suffer from strong visual bias -- where answers can be inferred from visual data alone -- and provide only aggregate scores that conflate multiple sources of error. This makes it difficult to determine whether models struggle with visual understanding, audio interpretation, or audio-visual alignment. In this work, we introduce DAVE (Diagnostic Audio Visual Evaluation), a novel benchmark dataset designed to systematically evaluate audio-visual models across controlled challenges. DAVE alleviates existing limitations by (i) ensuring both modalities are necessary to answer correctly and (ii) decoupling evaluation into atomic subcategories. Our detailed analysis of state-of-the-art models reveals specific failure modes and provides targeted insights for improvement. By offering this standardized diagnostic framework, we aim to facilitate more robust development of audio-visual models. The dataset is released: https://github.com/gorjanradevski/dave

Recent advances in semi-supervised semantic segmentation have been heavily reliant on pseudo labeling to compensate for limited labeled data, disregarding the valuable relational knowledge among semantic concepts. To bridge this gap, we devise LogicDiag, a brand new neural-logic semi-supervised learning framework. Our key insight is that conflicts within pseudo labels, identified through symbolic knowledge, can serve as strong yet commonly ignored learning signals. LogicDiag resolves such conflicts via reasoning with logic-induced diagnoses, enabling the recovery of (potentially) erroneous pseudo labels, ultimately alleviating the notorious error accumulation problem. We showcase the practical application of LogicDiag in the data-hungry segmentation scenario, where we formalize the structured abstraction of semantic concepts as a set of logic rules. Extensive experiments on three standard semi-supervised semantic segmentation benchmarks demonstrate the effectiveness and generality of LogicDiag. Moreover, LogicDiag highlights the promising opportunities arising from the systematic integration of symbolic reasoning into the prevalent statistical, neural learning approaches.

Recent progress in Large Vision-Language Models (LVLMs) has enabled promising applications in medical tasks, such as report generation and visual question answering. However, existing benchmarks focus mainly on the final diagnostic answer, offering limited insight into whether models engage in clinically meaningful reasoning. To address this, we present CheXStruct and CXReasonBench, a structured pipeline and benchmark built on the publicly available MIMIC-CXR-JPG dataset. CheXStruct automatically derives a sequence of intermediate reasoning steps directly from chest X-rays, such as segmenting anatomical regions, deriving anatomical landmarks and diagnostic measurements, computing diagnostic indices, and applying clinical thresholds. CXReasonBench leverages this pipeline to evaluate whether models can perform clinically valid reasoning steps and to what extent they can learn from structured guidance, enabling fine-grained and transparent assessment of diagnostic reasoning. The benchmark comprises 18,988 QA pairs across 12 diagnostic tasks and 1,200 cases, each paired with up to 4 visual inputs, and supports multi-path, multi-stage evaluation including visual grounding via anatomical region selection and diagnostic measurements. Even the strongest of 10 evaluated LVLMs struggle with structured reasoning and generalization, often failing to link abstract knowledge with anatomically grounded visual interpretation. The code is available at https://github.com/ttumyche/CXReasonBench

Recent Audio Multimodal Large Language Models (Audio MLLMs) demonstrate impressive performance on speech benchmarks, yet it remains unclear whether these models genuinely process acoustic signals or rely on text-based semantic inference. To systematically study this question, we introduce DEAF (Diagnostic Evaluation of Acoustic Faithfulness), a benchmark of over 2,700 conflict stimuli spanning three acoustic dimensions: emotional prosody, background sounds, and speaker identity. Then, we design a controlled multi-level evaluation framework that progressively increases textual influence, ranging from semantic conflicts in the content to misleading prompts and their combination, allowing us to disentangle content-driven bias from prompt-induced sycophancy. We further introduce diagnostic metrics to quantify model reliance on textual cues over acoustic signals. Our evaluation of seven Audio MLLMs reveals a consistent pattern of text dominance: models are sensitive to acoustic variations, yet predictions are predominantly driven by textual inputs, revealing a gap between high performance on standard speech benchmarks and genuine acoustic understanding.

Lung cancer remains the leading cause of cancer-related mortality worldwide, and early detection through low-dose computed tomography (LDCT) has shown significant promise in reducing death rates. With the growing integration of artificial intelligence (AI) into medical imaging, the development and evaluation of robust AI models require access to large, well-annotated datasets. In this study, we introduce the utility of Duke Lung Cancer Screening (DLCS) Dataset, the largest open-access LDCT dataset with over 2,000 scans and 3,000 expert-verified nodules. We benchmark deep learning models for both 3D nodule detection and lung cancer classification across internal and external datasets including LUNA16, LUNA25, and NLST-3D+. For detection, we develop two MONAI-based RetinaNet models (DLCSDmD and LUNA16-mD), evaluated using the Competition Performance Metric (CPM). For classification, we compare five models, including state-of-the-art pretrained models (Models Genesis, Med3D), a selfsupervised foundation model (FMCB), a randomly initialized ResNet50, and proposed a novel Strategic Warm-Start++ (SWS++) model. SWS++ uses curated candidate patches to pretrain a classification backbone within the same detection pipeline, enabling task-relevant feature learning. Our models demonstrated strong generalizability, with SWS++ achieving comparable or superior performance to existing foundational models across multiple datasets (AUC: 0.71 to 0.90). All code, models, and data are publicly released to promote reproducibility and collaboration. This work establishes a standardized benchmarking resource for lung cancer AI research, supporting future efforts in model development, validation, and clinical translation.

Large language models (LLMs) now perform strongly on many public math suites, yet frontier separation within mathematics increasingly suffers from ceiling effects. We present two complementary benchmarks: SKYLENAGE-ReasoningMATH, a 100-item, structure-aware diagnostic set with per-item metadata on length, numeric density, and symbolic complexity; and SKYLENAGE-MATH, a 150-item contest-style suite spanning four stages from high school to doctoral under a seven-subject taxonomy. We evaluate fifteen contemporary LLM variants under a single setup and analyze subject x model and grade x model performance. On the contest suite, the strongest model reaches 44% while the runner-up reaches 37%; accuracy declines from high school to doctoral, and top systems exhibit a doctoral-to-high-school retention near 79%. On the reasoning set, the best model attains 81% overall, and hardest-slice results reveal clear robustness gaps between leaders and the mid-tier. In summary, we release SKYLENAGE-ReasoningMATH and report aggregate results for SKYLENAGE-MATH; together, SKYLENAGE provides a hard, reasoning-centered and broadly covering math benchmark with calibrated difficulty and rich metadata, serving as a reference benchmark for future evaluations of mathematical reasoning.

The rapid progress of text-to-image (T2I) models has unlocked unprecedented creative potential, yet their ability to faithfully render complex prompts involving multiple objects, attributes, and spatial relationships remains a significant bottleneck. Progress is hampered by a lack of adequate evaluation methods; current benchmarks are often restricted to closed-set vocabularies, lack fine-grained diagnostic capabilities, and fail to provide the interpretable feedback necessary to diagnose and remedy specific compositional failures. We solve these challenges by introducing SANEval (Spatial, Attribute, and Numeracy Evaluation), a comprehensive benchmark that establishes a scalable new pipeline for open-vocabulary compositional evaluation. SANEval combines a large language model (LLM) for deep prompt understanding with an LLM-enhanced, open-vocabulary object detector to robustly evaluate compositional adherence, unconstrained by a fixed vocabulary. Through extensive experiments on six state-of-the-art T2I models, we demonstrate that SANEval's automated evaluations provide a more faithful proxy for human assessment; our metric achieves a Spearman's rank correlation with statistically different results than those of existing benchmarks across tasks of attribute binding, spatial relations, and numeracy. To facilitate future research in compositional T2I generation and evaluation, we will release the SANEval dataset and our open-source evaluation pipeline.

Dynamic graph learning methods have recently emerged as powerful tools for modelling relational data evolving through time. However, despite extensive benchmarking efforts, it remains unclear whether current Temporal Graph Neural Networks (TGNNs) effectively capture core temporal patterns such as periodicity, cause-and-effect, and long-range dependencies. In this work, we introduce the Temporal Graph Reasoning Benchmark (T-GRAB), a comprehensive set of synthetic tasks designed to systematically probe the capabilities of TGNNs to reason across time. T-GRAB provides controlled, interpretable tasks that isolate key temporal skills: counting/memorizing periodic repetitions, inferring delayed causal effects, and capturing long-range dependencies over both spatial and temporal dimensions. We evaluate 11 temporal graph learning methods on these tasks, revealing fundamental shortcomings in their ability to generalize temporal patterns. Our findings offer actionable insights into the limitations of current models, highlight challenges hidden by traditional real-world benchmarks, and motivate the development of architectures with stronger temporal reasoning abilities. The code for T-GRAB can be found at: https://github.com/alirezadizaji/T-GRAB.

As Large Multimodal Models (LMMs) scale up and reinforcement learning (RL) methods mature, LMMs have made notable progress in complex reasoning and decision making. Yet training still relies on static data and fixed recipes, making it difficult to diagnose capability blind spots or provide dynamic, targeted reinforcement. Motivated by findings that test driven error exposure and feedback based correction outperform repetitive practice, we propose Diagnostic-driven Progressive Evolution (DPE), a spiral loop where diagnosis steers data generation and reinforcement, and each iteration re-diagnoses the updated model to drive the next round of targeted improvement. DPE has two key components. First, multiple agents annotate and quality control massive unlabeled multimodal data, using tools such as web search and image editing to produce diverse, realistic samples. Second, DPE attributes failures to specific weaknesses, dynamically adjusts the data mixture, and guides agents to generate weakness focused data for targeted reinforcement. Experiments on Qwen3-VL-8B-Instruct and Qwen2.5-VL-7B-Instruct show stable, continual gains across eleven benchmarks, indicating DPE as a scalable paradigm for continual LMM training under open task distributions. Our code, models, and data are publicly available at https://github.com/hongruijia/DPE.

Image captioning, situated at the intersection of computer vision and natural language processing, requires a sophisticated understanding of both visual scenes and linguistic structure. While modern approaches are dominated by large-scale Transformer architectures, this paper documents a systematic, iterative development of foundational image captioning models, progressing from a simple CNN-LSTM encoder-decoder to a competitive attention-based system. This paper presents a series of five models, beginning with Genesis and concluding with Nexus, an advanced model featuring an EfficientNetV2B3 backbone and a dynamic attention mechanism. The experiments chart the impact of architectural enhancements and demonstrate a key finding within the classic CNN-LSTM paradigm: merely upgrading the visual backbone without a corresponding attention mechanism can degrade performance, as the single-vector bottleneck cannot transmit the richer visual detail. This insight validates the architectural shift to attention. Trained on the MS COCO 2017 dataset, the final model, Nexus, achieves a BLEU-4 score of 31.4, surpassing several foundational benchmarks and validating the iterative design process. This work provides a clear, replicable blueprint for understanding the core architectural principles that underpin modern vision-language tasks.

Large language models have shown promise in clinical decision making, but current approaches struggle to localize and correct errors at specific steps of the reasoning process. This limitation is critical in medicine, where identifying and addressing reasoning errors is essential for accurate diagnosis and effective patient care. We introduce Med-PRM, a process reward modeling framework that leverages retrieval-augmented generation to verify each reasoning step against established medical knowledge bases. By verifying intermediate reasoning steps with evidence retrieved from clinical guidelines and literature, our model can precisely assess the reasoning quality in a fine-grained manner. Evaluations on five medical QA benchmarks and two open-ended diagnostic tasks demonstrate that Med-PRM achieves state-of-the-art performance, with improving the performance of base models by up to 13.50% using Med-PRM. Moreover, we demonstrate the generality of Med-PRM by integrating it in a plug-and-play fashion with strong policy models such as Meerkat, achieving over 80\% accuracy on MedQA for the first time using small-scale models of 8 billion parameters. Our code and data are available at: https://med-prm.github.io/

Large Vision-Language Models (LVLMs) are increasingly being explored for applications in telemedicine, yet their ability to engage with diverse patient behaviors remains underexplored. We introduce 3MDBench (Medical Multimodal Multi-agent Dialogue Benchmark), an open-source evaluation framework designed to assess LLM-driven medical consultations. Unlike existing benchmarks, 3MDBench simulates real-world patient variability by incorporating four temperament-driven Patient Agents and an Assessor Agent that evaluates diagnostic accuracy and dialogue quality. The benchmark integrates textual and image-based patient data across 34 common diagnoses, mirroring real-world telemedicine interactions. Under different diagnostic strategies, we evaluate state-of-the-art LVLMs. Our findings demonstrate that incorporating dialogue improves the F1 score from 50.4 to 54.2 compared to non-dialogue settings, underscoring the value of context-driven, information-seeking questioning. Additionally, we demonstrate that multimodal inputs enhance diagnostic efficiency. Image-supported models outperform text-only counterparts by raising the diagnostic F1 score from 52.8 to 54.2 in a similar dialogue setting. Finally, we suggest an approach that improves the diagnostic F1-score to 70.3 by training the CNN model on the diagnosis prediction task and incorporating its top-3 predictions into the LVLM context. 3MDBench provides a reproducible and extendable evaluation framework for AI-driven medical assistants. It offers insights into how patient temperament, dialogue strategies, and multimodal reasoning influence diagnosis quality. By addressing real-world complexities in telemedicine, our benchmark paves the way for more empathetic, reliable, and context-aware AI-driven healthcare solutions. The source code of our benchmark is publicly available: https://github.com/univanxx/3mdbench

The capability of Unified Multimodal Models (UMMs) to apply world knowledge across diverse tasks remains a critical, unresolved challenge. Existing benchmarks fall short, offering only siloed, single-task evaluations with limited diagnostic power. To bridge this gap, we propose AEGIS (i.e., Assessing Editing, Generation, Interpretation-Understanding for Super-intelligence), a comprehensive multi-task benchmark covering visual understanding, generation, editing, and interleaved generation. AEGIS comprises 1,050 challenging, manually-annotated questions spanning 21 topics (including STEM, humanities, daily life, etc.) and 6 reasoning types. To concretely evaluate the performance of UMMs in world knowledge scope without ambiguous metrics, we further propose Deterministic Checklist-based Evaluation (DCE), a protocol that replaces ambiguous prompt-based scoring with atomic ``Y/N'' judgments, to enhance evaluation reliability. Our extensive experiments reveal that most UMMs exhibit severe world knowledge deficits and that performance degrades significantly with complex reasoning. Additionally, simple plug-in reasoning modules can partially mitigate these vulnerabilities, highlighting a promising direction for future research. These results highlight the importance of world-knowledge-based reasoning as a critical frontier for UMMs.

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios. Specifically, current LLMs suffer from three critical limitations: (1) generating hallucinated medical content due to weak grounding in verified knowledge, (2) asking redundant or inefficient questions rather than discriminative ones that hinder diagnostic progress, and (3) losing coherence over multi-turn dialogues, leading to contradictory or inconsistent conclusions. To address these challenges, we propose MedKGI, a diagnostic framework grounded in clinical practices. MedKGI integrates a medical knowledge graph (KG) to constrain reasoning to validated medical ontologies, selects questions based on information gain to maximize diagnostic efficiency, and adopts an OSCE-format structured state to maintain consistent evidence tracking across turns. Experiments on clinical benchmarks show that MedKGI outperforms strong LLM baselines in both diagnostic accuracy and inquiry efficiency, improving dialogue efficiency by 30% on average while maintaining state-of-the-art accuracy.

Multimodal large language models (MLLMs) hold significant potential in medical applications, including disease diagnosis and clinical decision-making. However, these tasks require highly accurate, context-sensitive, and professionally aligned responses, making reliable reward models and judges critical. Despite their importance, medical reward models (MRMs) and judges remain underexplored, with no dedicated benchmarks addressing clinical requirements. Existing benchmarks focus on general MLLM capabilities or evaluate models as solvers, neglecting essential evaluation dimensions like diagnostic accuracy and clinical relevance. To address this, we introduce Med-RewardBench, the first benchmark specifically designed to evaluate MRMs and judges in medical scenarios. Med-RewardBench features a multimodal dataset spanning 13 organ systems and 8 clinical departments, with 1,026 expert-annotated cases. A rigorous three-step process ensures high-quality evaluation data across six clinically critical dimensions. We evaluate 32 state-of-the-art MLLMs, including open-source, proprietary, and medical-specific models, revealing substantial challenges in aligning outputs with expert judgment. Additionally, we develop baseline models that demonstrate substantial performance improvements through fine-tuning.

Despite widespread deployment of Large Language Models, systematic evaluation of instruction-following capabilities remains challenging. While comprehensive benchmarks exist, focused assessments that quickly diagnose specific instruction adherence patterns are valuable. As newer models may be trained on existing benchmarks, novel evaluation approaches are needed to assess genuine capabilities rather than memorized performance. This paper presents a streamlined evaluation framework using twenty carefully designed prompts to assess LLM instruction-following across diverse task categories. We demonstrate this framework through a large-scale empirical study conducted on October 14, 2025, testing 256 verified working models from 331 available via OpenRouter. To ensure methodological rigor and prevent selection bias, we first verified each model's basic functionality before inclusion. Unlike large-scale benchmarks requiring extensive computational resources, our approach offers a practical diagnostic tool researchers and practitioners can readily apply. Our methodology builds upon verifiable instructions while introducing a compact test suite balancing comprehensiveness with efficiency. Each prompt targets distinct aspects of instruction following, including format compliance, content constraints, logical sequencing, and multi-step task execution. We evaluate models from major providers (OpenAI, Anthropic, Google, Meta, Mistral) and emerging implementations (Qwen, DeepSeek, community models), providing comparative performance analysis. Our findings reveal consistent failure modes and identify specific instruction types posing particular challenges. This work contributes both a practical evaluation tool and one of the most comprehensive empirical analyses of instruction-following capabilities across the contemporary LLM landscape.

Small object-centric spatial understanding in indoor videos remains a significant challenge for multimodal large language models (MLLMs), despite its practical value for object search and assistive applications. Although existing benchmarks have advanced video spatial intelligence, embodied reasoning, and diagnostic perception, no existing benchmark directly evaluates whether a model can localize a target object in video and express its position with sufficient precision for downstream use. In this work, we introduce PinpointQA, the first dataset and benchmark for small object-centric spatial understanding in indoor videos. Built from ScanNet++ and ScanNet200, PinpointQA comprises 1,024 scenes and 10,094 QA pairs organized into four progressively challenging tasks: Target Presence Verification (TPV), Nearest Reference Identification (NRI), Fine-Grained Spatial Description (FSD), and Structured Spatial Prediction (SSP). The dataset is built from intermediate spatial representations, with QA pairs generated automatically and further refined through quality control. Experiments on representative MLLMs reveal a consistent capability gap along the progressive chain, with SSP remaining particularly difficult. Supervised fine-tuning on PinpointQA yields substantial gains, especially on the harder tasks, demonstrating that PinpointQA serves as both a diagnostic benchmark and an effective training dataset. The dataset and project page are available at https://rainchowz.github.io/PinpointQA.

Multi-agent systems (MAS) are critical for automating complex tasks, yet their practical deployment is severely hampered by the challenge of failure attribution. Current diagnostic tools, which rely on statistical correlations, are fundamentally inadequate; on challenging benchmarks like Who\&When, state-of-the-art methods achieve less than 15\% accuracy in locating the root-cause step of a failure. To address this critical gap, we introduce the first failure attribution framework for MAS grounded in multi-granularity causal inference. Our approach makes two key technical contributions: (1) a performance causal inversion principle, which correctly models performance dependencies by reversing the data flow in execution logs, combined with Shapley values to accurately assign agent-level blame; (2) a novel causal discovery algorithm, CDC-MAS, that robustly identifies critical failure steps by tackling the non-stationary nature of MAS interaction data. The framework's attribution results directly fuel an automated optimization loop, generating targeted suggestions whose efficacy is validated via counterfactual simulations. Evaluations on the Who\&When and TRAIL benchmarks demonstrate a significant leap in performance. Our method achieves up to 36.2\% step-level accuracy. Crucially, the generated optimizations boost overall task success rates by an average of 22.4\%. This work provides a principled and effective solution for debugging complex agent interactions, paving the way for more reliable and interpretable multi-agent systems.

Achieving human-like perception and reasoning in Multimodal Large Language Models (MLLMs) remains a central challenge in artificial intelligence. While recent research has primarily focused on enhancing reasoning capabilities in MLLMs, a fundamental question persists: Can Multimodal Large Language Models truly perceive the world as humans do? This paper shifts focus from reasoning to perception. Rather than constructing benchmarks specifically for reasoning, we introduce the Turing Eye Test (TET), a challenging perception-oriented benchmark comprising four diagnostic tasks that evaluate MLLMs' performance on synthetic images that humans process intuitively. Our findings reveal that state-of-the-art MLLMs exhibit catastrophic failures on our perceptual tasks trivial for humans. Both in-context learning and training on language backbone-effective for previous benchmarks-fail to improve performance on our tasks, while fine-tuning the vision tower enables rapid adaptation, suggesting that our benchmark poses challenges for vision tower generalization rather than for the knowledge and reasoning capabilities of the language backbone-a key gap between current MLLMs and human perception. We release a representative subset of TET tasks in this version, and will introduce more diverse tasks and methods to enhance visual generalization in future work.

Robust benchmarks are crucial for evaluating Multimodal Large Language Models (MLLMs). Yet we find that models can ace many multimodal benchmarks without strong visual understanding, instead exploiting biases, linguistic priors, and superficial patterns. This is especially problematic for vision-centric benchmarks that are meant to require visual inputs. We adopt a diagnostic principle for benchmark design: if a benchmark can be gamed, it will be. Designers should therefore try to ``game'' their own benchmarks first, using diagnostic and debiasing procedures to systematically identify and mitigate non-visual biases. Effective diagnosis requires directly ``training on the test set'' -- probing the released test set for its intrinsic, exploitable patterns. We operationalize this standard with two components. First, we diagnose benchmark susceptibility using a ``Test-set Stress-Test'' (TsT) methodology. Our primary diagnostic tool involves fine-tuning a powerful Large Language Model via k-fold cross-validation on exclusively the non-visual, textual inputs of the test set to reveal shortcut performance and assign each sample a bias score s(x). We complement this with a lightweight Random Forest-based diagnostic operating on hand-crafted features for fast, interpretable auditing. Second, we debias benchmarks by filtering high-bias samples using an ``Iterative Bias Pruning'' (IBP) procedure. Applying this framework to four benchmarks -- VSI-Bench, CV-Bench, MMMU, and VideoMME -- we uncover pervasive non-visual biases. As a case study, we apply our full framework to create VSI-Bench-Debiased, demonstrating reduced non-visual solvability and a wider vision-blind performance gap than the original.

Integrating language models (LMs) in healthcare systems holds great promise for improving medical workflows and decision-making. However, a critical barrier to their real-world adoption is the lack of reliable evaluation of their trustworthiness, especially in multilingual healthcare settings. Existing LMs are predominantly trained in high-resource languages, making them ill-equipped to handle the complexity and diversity of healthcare queries in mid- and low-resource languages, posing significant challenges for deploying them in global healthcare contexts where linguistic diversity is key. In this work, we present CLINIC, a Comprehensive Multilingual Benchmark to evaluate the trustworthiness of language models in healthcare. CLINIC systematically benchmarks LMs across five key dimensions of trustworthiness: truthfulness, fairness, safety, robustness, and privacy, operationalized through 18 diverse tasks, spanning 15 languages (covering all the major continents), and encompassing a wide array of critical healthcare topics like disease conditions, preventive actions, diagnostic tests, treatments, surgeries, and medications. Our extensive evaluation reveals that LMs struggle with factual correctness, demonstrate bias across demographic and linguistic groups, and are susceptible to privacy breaches and adversarial attacks. By highlighting these shortcomings, CLINIC lays the foundation for enhancing the global reach and safety of LMs in healthcare across diverse languages.

Linguistic expressions of emotions such as depression, anxiety, and trauma-related states are pervasive in clinical notes, counseling dialogues, and online mental health communities, and accurate recognition of these emotions is essential for clinical triage, risk assessment, and timely intervention. Although large language models (LLMs) have demonstrated strong generalization ability in emotion analysis tasks, their diagnostic reliability in high-stakes, context-intensive medical settings remains highly sensitive to prompt design. Moreover, existing methods face two key challenges: emotional comorbidity, in which multiple intertwined emotional states complicate prediction, and inefficient exploration of clinically relevant cues. To address these challenges, we propose APOLO (Automated Prompt Optimization for Linguistic Emotion Diagnosis), a framework that systematically explores a broader and finer-grained prompt space to improve diagnostic efficiency and robustness. APOLO formulates instruction refinement as a Partially Observable Markov Decision Process and adopts a multi-agent collaboration mechanism involving Planner, Teacher, Critic, Student, and Target roles. Within this closed-loop framework, the Planner defines an optimization trajectory, while the Teacher-Critic-Student agents iteratively refine prompts to enhance reasoning stability and effectiveness, and the Target agent determines whether to continue optimization based on performance evaluation. Experimental results show that APOLO consistently improves diagnostic accuracy and robustness across domain-specific and stratified benchmarks, demonstrating a scalable and generalizable paradigm for trustworthy LLM applications in mental healthcare.

Deep learning has enabled the development of highly robust foundation models for various pathological tasks across diverse diseases and patient cohorts. Among these models, vision-language pre-training, which leverages large-scale paired data to align pathology image and text embedding spaces, and provides a novel zero-shot paradigm for downstream tasks. However, existing models have been primarily data-driven and lack the incorporation of domain-specific knowledge, which limits their performance in cancer diagnosis, especially for rare tumor subtypes. To address this limitation, we establish a Knowledge-enhanced Pathology (KEEP) foundation model that harnesses disease knowledge to facilitate vision-language pre-training. Specifically, we first construct a disease knowledge graph (KG) that covers 11,454 human diseases with 139,143 disease attributes, including synonyms, definitions, and hypernym relations. We then systematically reorganize the millions of publicly available noisy pathology image-text pairs, into 143K well-structured semantic groups linked through the hierarchical relations of the disease KG. To derive more nuanced image and text representations, we propose a novel knowledge-enhanced vision-language pre-training approach that integrates disease knowledge into the alignment within hierarchical semantic groups instead of unstructured image-text pairs. Validated on 18 diverse benchmarks with more than 14,000 whole slide images (WSIs), KEEP achieves state-of-the-art performance in zero-shot cancer diagnostic tasks. Notably, for cancer detection, KEEP demonstrates an average sensitivity of 89.8% at a specificity of 95.0% across 7 cancer types. For cancer subtyping, KEEP achieves a median balanced accuracy of 0.456 in subtyping 30 rare brain cancers, indicating strong generalizability for diagnosing rare tumors.

Given a question, a language model (LM) implicitly encodes a distribution over possible answers. In practice, post-training procedures for LMs often collapse this distribution onto a single dominant mode. While this is generally not a problem for benchmark-style evaluations that assume one correct answer, many real-world tasks inherently involve multiple valid answers or irreducible uncertainty. Examples include medical diagnosis, ambiguous question answering, and settings with incomplete information. In these cases, we would like LMs to generate multiple plausible hypotheses, ideally with confidence estimates for each one, and without computationally intensive repeated sampling to generate non-modal answers. This paper describes a multi-answer reinforcement learning approach for training LMs to perform distributional reasoning over multiple answers during inference. We modify the RL objective to enable models to explicitly generate multiple candidate answers in a single forward pass, internalizing aspects of inference-time search into the model's generative process. Across question-answering, medical diagnostic, and coding benchmarks, we observe improved diversity, coverage, and set-level calibration scores compared to single answer trained baselines. Models trained with our approach require fewer tokens to generate multiple answers than competing approaches. On coding tasks, they are also substantially more accurate. These results position multi-answer RL as a principled and compute-efficient alternative to inference-time scaling procedures such as best-of-k. Code and more information can be found at https://multi-answer-rl.github.io/.

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic reasoning abilities of medical large language models (LLMs) have not been rigorously evaluated. To address these gaps, we present MedDialogRubrics, a novel benchmark comprising 5,200 synthetically constructed patient cases and over 60,000 fine-grained evaluation rubrics generated by LLMs and subsequently refined by clinical experts, specifically designed to assess the multi-turn diagnostic capabilities of LLM. Our framework employs a multi-agent system to synthesize realistic patient records and chief complaints from underlying disease knowledge without accessing real-world electronic health records, thereby mitigating privacy and data-governance concerns. We design a robust Patient Agent that is limited to a set of atomic medical facts and augmented with a dynamic guidance mechanism that continuously detects and corrects hallucinations throughout the dialogue, ensuring internal coherence and clinical plausibility of the simulated cases. Furthermore, we propose a structured LLM-based and expert-annotated rubric-generation pipeline that retrieves Evidence-Based Medicine (EBM) guidelines and utilizes the reject sampling to derive a prioritized set of rubric items ("must-ask" items) for each case. We perform a comprehensive evaluation of state-of-the-art models and demonstrate that, across multiple assessment dimensions, current models face substantial challenges. Our results indicate that improving medical dialogue will require advances in dialogue management architectures, not just incremental tuning of the base-model.

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11 biomedical QA benchmarks into reasoning- and knowledge-focused subsets using a PubMedBERT classifier that reaches 81 percent accuracy, comparable to human performance. Our analysis shows that only 32.8 percent of questions require complex reasoning. We evaluate biomedical models (HuatuoGPT-o1, MedReason, m1) and general-domain models (DeepSeek-R1, o4-mini, Qwen3), finding consistent gaps between knowledge and reasoning performance. For example, m1 scores 60.5 on knowledge but only 47.1 on reasoning. In adversarial tests where models are misled with incorrect initial reasoning, biomedical models degrade sharply, while larger or RL-trained general models show more robustness. To address this, we train BioMed-R1 using fine-tuning and reinforcement learning on reasoning-heavy examples. It achieves the strongest performance among similarly sized models. Further gains may come from incorporating clinical case reports and training with adversarial and backtracking scenarios.

Recent advances in medical multi-modal models focus on specialized image analysis like dermatology, pathology, or radiology. However, they do not fully capture the complexity of real-world clinical diagnostics, which involve heterogeneous inputs and require ongoing contextual understanding during patient-physician interactions. To bridge this gap, we introduce PulseMind, a new family of multi-modal diagnostic models that integrates a systematically curated dataset, a comprehensive evaluation benchmark, and a tailored training framework. Specifically, we first construct a diagnostic dataset, MediScope, which comprises 98,000 real-world multi-turn consultations and 601,500 medical images, spanning over 10 major clinical departments and more than 200 sub-specialties. Then, to better reflect the requirements of real-world clinical diagnosis, we develop the PulseMind Benchmark, a multi-turn diagnostic consultation benchmark with a four-dimensional evaluation protocol comprising proactiveness, accuracy, usefulness, and language quality. Finally, we design a training framework tailored for multi-modal clinical diagnostics, centered around a core component named Comparison-based Reinforcement Policy Optimization (CRPO). Compared to absolute score rewards, CRPO uses relative preference signals from multi-dimensional com-parisons to provide stable and human-aligned training guidance. Extensive experiments demonstrate that PulseMind achieves competitive performance on both the diagnostic consultation benchmark and public medical benchmarks.

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic tests to determine lymphoma subtypes, a process requiring costly equipment, skilled personnel, and causing treatment delays. Deep learning methods could assist pathologists by extracting diagnostic information from routinely available HE-stained slides, yet comprehensive benchmarks for lymphoma subtyping on multicenter data are lacking. In this work, we present the first multicenter lymphoma benchmarking dataset covering four common lymphoma subtypes and healthy control tissue. We systematically evaluate five publicly available pathology foundation models (H-optimus-1, H0-mini, Virchow2, UNI2, Titan) combined with attention-based (AB-MIL) and transformer-based (TransMIL) multiple instance learning aggregators across three magnifications (10x, 20x, 40x). On in-distribution test sets, models achieve multiclass balanced accuracies exceeding 80% across all magnifications, with all foundation models performing similarly and both aggregation methods showing comparable results. The magnification study reveals that 40x resolution is sufficient, with no performance gains from higher resolutions or cross-magnification aggregation. However, on out-of-distribution test sets, performance drops substantially to around 60%, highlighting significant generalization challenges. To advance the field, larger multicenter studies covering additional rare lymphoma subtypes are needed. We provide an automated benchmarking pipeline to facilitate such future research.

While Large Language Models (LLMs) achieve expert-level performance on standard medical benchmarks through single-hop factual recall, they severely struggle with the complex, multi-hop diagnostic reasoning required in real-world clinical settings. A primary obstacle is "shortcut learning", where models exploit highly connected, generic hub nodes (e.g., "inflammation") in knowledge graphs to bypass authentic micro-pathological cascades. To address this, we introduce ShatterMed-QA, a bilingual benchmark of 10,558 multi-hop clinical questions designed to rigorously evaluate deep diagnostic reasoning. Our framework constructs a topology-regularized medical Knowledge Graph using a novel k-Shattering algorithm, which physically prunes generic hubs to explicitly sever logical shortcuts. We synthesize the evaluation vignettes by applying implicit bridge entity masking and topology-driven hard negative sampling, forcing models to navigate biologically plausible distractors without relying on superficial elimination. Comprehensive evaluations of 21 LLMs reveal massive performance degradation on our multi-hop tasks, particularly among domain-specific models. Crucially, restoring the masked evidence via Retrieval-Augmented Generation (RAG) triggers near-universal performance recovery, validating ShatterMed-QA's structural fidelity and proving its efficacy in diagnosing the fundamental reasoning deficits of current medical AI. Explore the dataset, interactive examples, and full leaderboards at our project website: https://shattermed-qa-web.vercel.app/

This paper explores the advancements and applications of large-scale models in the medical field, with a particular focus on Medical Large Models (MedLMs). These models, encompassing Large Language Models (LLMs), Vision Models, 3D Large Models, and Multimodal Models, are revolutionizing healthcare by enhancing disease prediction, diagnostic assistance, personalized treatment planning, and drug discovery. The integration of graph neural networks in medical knowledge graphs and drug discovery highlights the potential of Large Graph Models (LGMs) in understanding complex biomedical relationships. The study also emphasizes the transformative role of Vision-Language Models (VLMs) and 3D Large Models in medical image analysis, anatomical modeling, and prosthetic design. Despite the challenges, these technologies are setting new benchmarks in medical innovation, improving diagnostic accuracy, and paving the way for personalized healthcare solutions. This paper aims to provide a comprehensive overview of the current state and future directions of large models in medicine, underscoring their significance in advancing global health.

To create culturally inclusive vision-language models (VLMs), the foremost requirement is developing a test benchmark that can diagnose the models' ability to respond to questions reflecting cultural elements. This paper addresses the necessity for such benchmarks, noting that existing research has relied on human annotators' manual efforts, which impedes diversity and efficiency. We propose a semi-automated pipeline for constructing cultural VLM benchmarks to enhance diversity and efficiency. This pipeline leverages human-VLM collaboration, where VLMs generate questions based on guidelines, human-annotated examples, and image-wise relevant knowledge, which are then reviewed by native speakers for quality and cultural relevance. The effectiveness of our adaptable pipeline is demonstrated through a specific application: creating a dataset tailored to Korean culture, dubbed K-Viscuit. The resulting benchmark features two types of questions: Type 1 questions measure visual recognition abilities, while Type 2 assess fine-grained visual reasoning skills. This ensures a thorough diagnosis of VLM models across various aspects. Our evaluation using K-Viscuit revealed that open-source models notably lag behind proprietary models in understanding Korean culture, highlighting areas for improvement. We provided diverse analyses of VLM performance across different cultural aspects. Besides, we explored the potential of incorporating external knowledge retrieval to enhance the generation process, suggesting future directions for improving cultural interpretation ability of VLMs. Our dataset and code will be made publicly available.

Artificial intelligence (AI) that can effectively learn ultrasound representations by integrating multi-source data holds significant promise for advancing clinical care. However, the scarcity of large labeled datasets in real-world clinical environments and the limited generalizability of task-specific models have hindered the development of generalizable clinical AI models for ultrasound applications. In this study, we present EchoCare, a novel ultrasound foundation model for generalist clinical use, developed via self-supervised learning on our curated, publicly available, large-scale dataset EchoCareData. EchoCareData comprises 4.5 million ultrasound images, sourced from over 23 countries across 5 continents and acquired via a diverse range of distinct imaging devices, thus encompassing global cohorts that are multi-center, multi-device, and multi-ethnic. Unlike prior studies that adopt off-the-shelf vision foundation model architectures, we introduce a hierarchical classifier into EchoCare to enable joint learning of pixel-level and representation-level features, capturing both global anatomical contexts and local ultrasound characteristics. With minimal training, EchoCare outperforms state-of-the-art comparison models across 10 representative ultrasound benchmarks of varying diagnostic difficulties, spanning disease diagnosis, lesion segmentation, organ detection, landmark prediction, quantitative regression, imaging enhancement and report generation. The code and pretrained model are publicly released, rendering EchoCare accessible for fine-tuning and local adaptation, supporting extensibility to additional applications. EchoCare provides a fully open and generalizable foundation model to boost the development of AI technologies for diverse clinical ultrasound applications.

Recent advances in agentic Large Language Models (LLMs) have positioned them as generalist planners capable of reasoning and acting across diverse tasks. However, existing agent benchmarks largely focus on symbolic or weakly grounded environments, leaving their performance in physics-constrained real-world domains underexplored. We introduce AstroReason-Bench, a comprehensive benchmark for evaluating agentic planning in Space Planning Problems (SPP), a family of high-stakes problems with heterogeneous objectives, strict physical constraints, and long-horizon decision-making. AstroReason-Bench integrates multiple scheduling regimes, including ground station communication and agile Earth observation, and provides a unified agent-oriented interaction protocol. Evaluating on a range of state-of-the-art open- and closed-source agentic LLM systems, we find that current agents substantially underperform specialized solvers, highlighting key limitations of generalist planning under realistic constraints. AstroReason-Bench offers a challenging and diagnostic testbed for future agentic research.

Spatial control is a core capability in controllable image generation. Advancements in layout-guided image generation have shown promising results on in-distribution (ID) datasets with similar spatial configurations. However, it is unclear how these models perform when facing out-of-distribution (OOD) samples with arbitrary, unseen layouts. In this paper, we propose LayoutBench, a diagnostic benchmark for layout-guided image generation that examines four categories of spatial control skills: number, position, size, and shape. We benchmark two recent representative layout-guided image generation methods and observe that the good ID layout control may not generalize well to arbitrary layouts in the wild (e.g., objects at the boundary). Next, we propose IterInpaint, a new baseline that generates foreground and background regions in a step-by-step manner via inpainting, demonstrating stronger generalizability than existing models on OOD layouts in LayoutBench. We perform quantitative and qualitative evaluation and fine-grained analysis on the four LayoutBench skills to pinpoint the weaknesses of existing models. Lastly, we show comprehensive ablation studies on IterInpaint, including training task ratio, crop&paste vs. repaint, and generation order. Project website: https://layoutbench.github.io

Vision-Language-Action (VLA) models achieve strong performance in robotic manipulation by leveraging pre-trained vision-language backbones. However, in downstream robotic settings, they are typically fine-tuned with limited data, leading to overfitting to specific instruction formulations and leaving robustness to paraphrased instructions underexplored. To study this gap, we introduce LIBERO-Para, a controlled benchmark that independently varies action expressions and object references for fine-grained analysis of linguistic generalization. Across seven VLA configurations (0.6B-7.5B), we observe consistent performance degradation of 22-52 pp under paraphrasing. This degradation is primarily driven by object-level lexical variation: even simple synonym substitutions cause large drops, indicating reliance on surface-level matching rather than semantic grounding. Moreover, 80-96% of failures arise from planning-level trajectory divergence rather than execution errors, showing that paraphrasing disrupts task identification. Binary success rate treats all paraphrases equally, obscuring whether models perform consistently across difficulty levels or rely on easier cases. To address this, we propose PRIDE, a metric that quantifies paraphrase difficulty using semantic and syntactic factors. Our benchmark and corresponding code are available at: https://github.com/cau-hai-lab/LIBERO-Para

While Multimodal Large Language Models (MLLMs) have achieved remarkable progress in visual understanding, they often struggle when faced with the unstructured and ambiguous nature of human-generated sketches. This limitation is particularly pronounced in the underexplored task of visual grading, where models should not only solve a problem but also diagnose errors in hand-drawn diagrams. Such diagnostic capabilities depend on complex structural, semantic, and metacognitive reasoning. To bridge this gap, we introduce SketchJudge, a novel benchmark tailored for evaluating MLLMs as graders of hand-drawn STEM diagrams. SketchJudge encompasses 1,015 hand-drawn student responses across four domains: geometry, physics, charts, and flowcharts, featuring diverse stylistic variations and distinct error types. Evaluations on SketchJudge demonstrate that even advanced MLLMs lag significantly behind humans, validating the benchmark's effectiveness in exposing the fragility of current vision-language alignment in symbolic and noisy contexts. All data, code, and evaluation scripts are publicly available at https://github.com/yuhangsu82/SketchJudge.

A recent trend in vision-language models (VLMs) has been to enhance their spatial cognition for embodied domains. Despite progress, existing evaluations have been limited both in paradigm and in coverage, hindering rapid, iterative model development. To address these limitations, we propose ESPIRE, a diagnostic benchmark for embodied spatial reasoning. ESPIRE offers a simulated world that physically grounds VLMs and evaluates them on spatial-reasoning-centric robotic tasks, thus narrowing the gap between evaluation and real-world deployment. To adapt VLMs to robotic tasks, we decompose each task into localization and execution, and frame both as generative problems, in stark contrast to predominant discriminative evaluations (e.g., via visual-question answering) that rely on distractors and discard execution. This decomposition further enables a fine-grained analysis beyond passive spatial reasoning toward reasoning to act. We systematically design ESPIRE both at the instruction level and at the environment level, ensuring broad coverage of spatial reasoning scenarios. We use ESPIRE to diagnose a range of frontier VLMs and provide in-depth analysis of their spatial reasoning behaviors.

We introduce EgoSchema, a very long-form video question-answering dataset, and benchmark to evaluate long video understanding capabilities of modern vision and language systems. Derived from Ego4D, EgoSchema consists of over 5000 human curated multiple choice question answer pairs, spanning over 250 hours of real video data, covering a very broad range of natural human activity and behavior. For each question, EgoSchema requires the correct answer to be selected between five given options based on a three-minute-long video clip. While some prior works have proposed video datasets with long clip lengths, we posit that merely the length of the video clip does not truly capture the temporal difficulty of the video task that is being considered. To remedy this, we introduce temporal certificate sets, a general notion for capturing the intrinsic temporal understanding length associated with a broad range of video understanding tasks & datasets. Based on this metric, we find EgoSchema to have intrinsic temporal lengths over 5.7x longer than the second closest dataset and 10x to 100x longer than any other video understanding dataset. Further, our evaluation of several current state-of-the-art video and language models shows them to be severely lacking in long-term video understanding capabilities. Even models with several billions of parameters achieve QA accuracy less than 33% (random is 20%) on the EgoSchema multi-choice question answering task, while humans achieve about 76% accuracy. We posit that {}, with its long intrinsic temporal structures and diverse complexity, would serve as a valuable evaluation probe for developing effective long-term video understanding systems in the future. Data and Zero-shot model evaluation code are open-sourced for both public and commercial use under the Ego4D license at http://egoschema.github.io

The recent success of natural language understanding (NLU) systems has been troubled by results highlighting the failure of these models to generalize in a systematic and robust way. In this work, we introduce a diagnostic benchmark suite, named CLUTRR, to clarify some key issues related to the robustness and systematicity of NLU systems. Motivated by classic work on inductive logic programming, CLUTRR requires that an NLU system infer kinship relations between characters in short stories. Successful performance on this task requires both extracting relationships between entities, as well as inferring the logical rules governing these relationships. CLUTRR allows us to precisely measure a model's ability for systematic generalization by evaluating on held-out combinations of logical rules, and it allows us to evaluate a model's robustness by adding curated noise facts. Our empirical results highlight a substantial performance gap between state-of-the-art NLU models (e.g., BERT and MAC) and a graph neural network model that works directly with symbolic inputs---with the graph-based model exhibiting both stronger generalization and greater robustness.

Long-form multimodal video understanding requires integrating vision, speech, and ambient audio with coherent long-range reasoning. Existing benchmarks emphasize either temporal length or multimodal richness, but rarely both and while some incorporate open-ended questions and advanced metrics, they mostly rely on single-score accuracy, obscuring failure modes. We introduce LongShOTBench, a diagnostic benchmark with open-ended, intent-driven questions; single- and multi-turn dialogues; and tasks requiring multimodal reasoning and agentic tool use across video, audio, and speech. Each item includes a reference answer and graded rubric for interpretable, and traceable evaluation. LongShOTBench is produced via a scalable, human-validated pipeline to ensure coverage and reproducibility. All samples in our LongShOTBench are human-verified and corrected. Furthermore, we present LongShOTAgent, an agentic system that analyzes long videos via preprocessing, search, and iterative refinement. On LongShOTBench, state-of-the-art MLLMs show large gaps: Gemini-2.5-Flash achieves 52.95%, open-source models remain below 30%, and LongShOTAgent attains 44.66%. These results underscore the difficulty of real-world long-form video understanding. LongShOTBench provides a practical, reproducible foundation for evaluating and improving MLLMs. All resources are available on GitHub: https://github.com/mbzuai-oryx/longshot.

Research on self-evolving language agents has accelerated, drawing increasing attention to their ability to create, adapt, and maintain tools from task requirements. However, existing benchmarks predominantly rely on predefined specifications, which limits scalability and hinders truly autonomous evolution. While recent studies attempt to dynamically generate tools, they primarily emphasize downstream performance, resulting in a "black-box" evaluation that makes it difficult to attribute failures to specific causes. To address this, we propose Tool-Genesis, a diagnostic benchmark designed to quantify agent capabilities across multiple dimensions, including interface compliance, functional correctness, and downstream utility. Tool-Genesis evaluates whether agents can construct task-relevant tools solely from abstract requirements (without preset specifications) and use them to solve realistic problems. Crucially, we find that even state-of-the-art models struggle to produce precise tool interfaces or executable logic in a one-shot setting. These minor initial flaws are amplified through the pipeline, leading to a sharp degradation in downstream metrics. We hope Tool-Genesis will guide future research toward training and steering models to synthesize persistent, general-purpose tools that better address real-world challenges.

Fine-grained spatio-temporal understanding is essential for video reasoning and embodied AI. Yet, while Multimodal Large Language Models (MLLMs) master static semantics, their grasp of temporal dynamics remains brittle. We present TimeBlind, a diagnostic benchmark for compositional spatio-temporal understanding. Inspired by cognitive science, TimeBlind categorizes fine-grained temporal understanding into three levels: recognizing atomic events, characterizing event properties, and reasoning about event interdependencies. Unlike benchmarks that conflate recognition with temporal reasoning, TimeBlind leverages a minimal-pairs paradigm: video pairs share identical static visual content but differ solely in temporal structure, utilizing complementary questions to neutralize language priors. Evaluating over 20 state-of-the-art MLLMs (e.g., GPT-5, Gemini 3 Pro) on 600 curated instances (2400 video-question pairs), reveals that the Instance Accuracy (correctly distinguishing both videos in a pair) of the best performing MLLM is only 48.2%, far below the human performance (98.2%). These results demonstrate that even frontier models rely heavily on static visual shortcuts rather than genuine temporal logic, positioning TimeBlind as a vital diagnostic tool for next-generation video understanding. Dataset and code are available at https://baiqi-li.github.io/timeblind_project/ .

We introduce InterChart, a diagnostic benchmark that evaluates how well vision-language models (VLMs) reason across multiple related charts, a task central to real-world applications such as scientific reporting, financial analysis, and public policy dashboards. Unlike prior benchmarks focusing on isolated, visually uniform charts, InterChart challenges models with diverse question types ranging from entity inference and trend correlation to numerical estimation and abstract multi-step reasoning grounded in 2-3 thematically or structurally related charts. We organize the benchmark into three tiers of increasing difficulty: (1) factual reasoning over individual charts, (2) integrative analysis across synthetically aligned chart sets, and (3) semantic inference over visually complex, real-world chart pairs. Our evaluation of state-of-the-art open and closed-source VLMs reveals consistent and steep accuracy declines as chart complexity increases. We find that models perform better when we decompose multi-entity charts into simpler visual units, underscoring their struggles with cross-chart integration. By exposing these systematic limitations, InterChart provides a rigorous framework for advancing multimodal reasoning in complex, multi-visual environments.

Reliable epidemiological reasoning requires synthesizing study evidence to infer disease burden, transmission dynamics, and intervention effects at the population level. Existing medical question answering benchmarks primarily emphasize clinical knowledge or patient-level reasoning, yet few systematically evaluate evidence-grounded epidemiological inference. We present EpiQAL, the first diagnostic benchmark for epidemiological question answering across diverse diseases, comprising three subsets built from open-access literature. The subsets respectively evaluate text-grounded factual recall, multi-step inference linking document evidence with epidemiological principles, and conclusion reconstruction with the Discussion section withheld. Construction combines expert-designed taxonomy guidance, multi-model verification, and retrieval-based difficulty control. Experiments on ten open models reveal that current LLMs show limited performance on epidemiological reasoning, with multi-step inference posing the greatest challenge. Model rankings shift across subsets, and scale alone does not predict success. Chain-of-Thought prompting benefits multi-step inference but yields mixed results elsewhere. EpiQAL provides fine-grained diagnostic signals for evidence grounding, inferential reasoning, and conclusion reconstruction.

We introduce FloorplanQA, a diagnostic benchmark for evaluating spatial reasoning in large-language models (LLMs). FloorplanQA is grounded in structured representations of indoor scenes, such as (e.g., kitchens, living rooms, bedrooms, bathrooms, and others), encoded symbolically in JSON or XML layouts. The benchmark covers core spatial tasks, including distance measurement, visibility, path finding, and object placement within constrained spaces. Our results across a variety of frontier open-source and commercial LLMs reveal that while models may succeed in shallow queries, they often fail to respect physical constraints, preserve spatial coherence, though they remain mostly robust to small spatial perturbations. FloorplanQA uncovers a blind spot in today's LLMs: inconsistent reasoning about indoor layouts. We hope this benchmark inspires new work on language models that can accurately infer and manipulate spatial and geometric properties in practical settings.

Vision-Language Models (VLMs) have advanced across multimodal benchmarks but still show clear gaps in ordinal number understanding, i.e., the ability to track relative positions and generalize to large indices. We present OrdinalBench, a diagnostic benchmark that standardizes ordinal number understanding as an evaluation task for VLMs. The core task is N-th object identification, defined by a starting reference and traversal rule. Task difficulty is controlled along three axes: (i) ordinal magnitude, from small numbers to extreme cases up to 300; (ii) arrangement complexity, from single loops to maze-like paths; and (iii) object count. The benchmark provides 39,000 question-answer pairs, each annotated with a ground-truth reasoning trajectory and balanced across difficulty levels for controlled large-scale testing. Beyond answer-only evaluation, our framework requires models to generate structured stepwise traces of the counting process and provides an open evaluation toolkit that measures both final accuracy and step-level path consistency. Zero-shot evaluations of GPT-5, Gemini 2.5 Flash Lite, Qwen2.5-VL, InternVL3.5, and Molmo reveal sharp degradation under large-ordinal and complex-path conditions, highlighting weak generalization despite strong scores on standard multimodal tasks. By framing ordinal number understanding as a core target, OrdinalBench provides a reproducible benchmark and diagnostic framework for developing VLMs with stronger sequential reasoning. All data and code are available at https://ordinalbench.github.io/

Text-to-video (T2V) generation models have made rapid progress in producing visually high-quality and temporally coherent videos. However, existing benchmarks primarily focus on perceptual quality, text-video alignment, or physical plausibility, leaving a critical aspect of action understanding largely unexplored: object state change (OSC) explicitly specified in the text prompt. OSC refers to the transformation of an object's state induced by an action, such as peeling a potato or slicing a lemon. In this paper, we introduce OSCBench, a benchmark specifically designed to assess OSC performance in T2V models. OSCBench is constructed from instructional cooking data and systematically organizes action-object interactions into regular, novel, and compositional scenarios to probe both in-distribution performance and generalization. We evaluate six representative open-source and proprietary T2V models using both human user study and multimodal large language model (MLLM)-based automatic evaluation. Our results show that, despite strong performance on semantic and scene alignment, current T2V models consistently struggle with accurate and temporally consistent object state changes, especially in novel and compositional settings. These findings position OSC as a key bottleneck in text-to-video generation and establish OSCBench as a diagnostic benchmark for advancing state-aware video generation models.

While generalist foundation models like Gemini and GPT-4o demonstrate impressive multi-modal competence, existing evaluations fail to test their intelligence in dynamic, interactive worlds. Static benchmarks lack agency, while interactive benchmarks suffer from a severe modal bottleneck, typically ignoring crucial auditory and temporal cues. To bridge this evaluation chasm, we introduce OmniPlay, a diagnostic benchmark designed not just to evaluate, but to probe the fusion and reasoning capabilities of agentic models across the full sensory spectrum. Built on a core philosophy of modality interdependence, OmniPlay comprises a suite of five game environments that systematically create scenarios of both synergy and conflict, forcing agents to perform genuine cross-modal reasoning. Our comprehensive evaluation of six leading omni-modal models reveals a critical dichotomy: they exhibit superhuman performance on high-fidelity memory tasks but suffer from systemic failures in challenges requiring robust reasoning and strategic planning. We demonstrate that this fragility stems from brittle fusion mechanisms, which lead to catastrophic performance degradation under modality conflict and uncover a counter-intuitive "less is more" paradox, where removing sensory information can paradoxically improve performance. Our findings suggest that the path toward robust AGI requires a research focus beyond scaling to explicitly address synergistic fusion. Our platform is available for anonymous review at https://github.com/fuqingbie/omni-game-benchmark.

Recent advances in multi-modal generative models have enabled significant progress in instruction-based image editing. However, while these models produce visually plausible outputs, their capacity for knowledge-based reasoning editing tasks remains under-explored. In this paper, we introduce KRIS-Bench (Knowledge-based Reasoning in Image-editing Systems Benchmark), a diagnostic benchmark designed to assess models through a cognitively informed lens. Drawing from educational theory, KRIS-Bench categorizes editing tasks across three foundational knowledge types: Factual, Conceptual, and Procedural. Based on this taxonomy, we design 22 representative tasks spanning 7 reasoning dimensions and release 1,267 high-quality annotated editing instances. To support fine-grained evaluation, we propose a comprehensive protocol that incorporates a novel Knowledge Plausibility metric, enhanced by knowledge hints and calibrated through human studies. Empirical results on 10 state-of-the-art models reveal significant gaps in reasoning performance, highlighting the need for knowledge-centric benchmarks to advance the development of intelligent image editing systems.

Recent advancements in Multimodal Large Language Models (MLLMs) have demonstrated impressive performance on standard visual reasoning benchmarks. However, there is growing concern that these models rely excessively on linguistic shortcuts rather than genuine visual grounding, a phenomenon we term Text Bias. In this paper, we investigate the fundamental tension between visual perception and linguistic priors. We decouple the sources of this bias into two dimensions: Internal Corpus Bias, stemming from statistical correlations in pretraining, and External Instruction Bias, arising from the alignment-induced tendency toward sycophancy. To quantify this effect, we introduce V-FAT (Visual Fidelity Against Text-bias), a diagnostic benchmark comprising 4,026 VQA instances across six semantic domains. V-FAT employs a Three-Level Evaluation Framework that systematically increases the conflict between visual evidence and textual information: (L1) internal bias from atypical images, (L2) external bias from misleading instructions, and (L3) synergistic bias where both coincide. We introduce the Visual Robustness Score (VRS), a metric designed to penalize "lucky" linguistic guesses and reward true visual fidelity. Our evaluation of 12 frontier MLLMs reveals that while models excel in existing benchmarks, they experience significant visual collapse under high linguistic dominance.

In this paper, we present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn diagnostic processes, adaptively select examinations, and commit to final diagnoses. Unlike instruction-tuned models trained on static case summaries, our method acquires diagnostic strategies through interactive exploration and outcome-based feedback. Our contributions are fourfold: (i) We present DiagGym, a diagnostics world model trained with electronic health records that emits examination outcomes conditioned on patient history and recommended examination, serving as a virtual clinical environment for realistic diagnosis training and evaluation; (ii) We train DiagAgent via end-to-end, multi-turn reinforcement learning to learn diagnostic policies that optimize both information yield and diagnostic accuracy; (iii) We introduce DiagBench, a diagnostic benchmark comprising 750 cases with physician-validated examination recommendations and 99 cases annotated with 973 physician-written rubrics on diagnosis process; (iv) we demonstrate superior performance across diverse diagnostic settings. DiagAgent significantly outperforms 10 state-of-the-art LLMs, including DeepSeek-v3 and GPT-4o, as well as two prompt-engineered agents. In single-turn settings, DiagAgent achieves 9.34% higher diagnostic accuracy and 44.03% improvement in examination recommendation hit ratio. In end-to-end settings, it delivers 15.12% increase in diagnostic accuracy and 23.09% boost in examination recommendation F1 score. In rubric-based evaluation, it surpasses the next-best model, Claude-sonnet-4, by 7.1% in weighted rubric score. These findings indicate that learning policies in interactive clinical environments confers dynamic and clinically meaningful diagnostic management abilities unattainable through passive training alone.

An ideal vision-language agent serves as a bridge between the human users and their surrounding physical world in real-world applications like autonomous driving and embodied agents, and proactively provides accurate and timely responses given user intents. An intriguing challenge arises when agents interact with the world as a dynamic data stream and ad-hoc queries from users: supporting knowledge for queries, namely evidence, usually appears asynchronously with the arrival time of queries, and agents need to ground their responses in historical data, present observations, and even future streams. We frame this challenge as Query-Evidence Asynchrony, where user queries and their supporting evidence typically arrive asynchronously in the streaming setting. This setting requires not only strong reasoning capabilities but also the ability to retain past observations and respond to queries with temporal awareness. In this paper, we introduce a diagnostic benchmark that evaluates Multimodal Large Language Models (MLLMs) on their ability to handle interaction with streaming data. Further, we present AViLA, Asynchronous Video-Language Agent for streaming data interaction that can handle ad-hoc queries and give time-aware responses. For this purpose, AViLA consists of three key modules: comprehensive memory retention, evidence identification, and evidence-grounded trigger, that are designed to maintain a general-purpose memory and respond readily and timely to queries. Our experiments show that existing models often fail to respond at appropriate times, while AViLA significantly improves both accuracy and temporal awareness. Our code and dataset will be publicly available.

Video foundation models generate visually realistic and temporally coherent content, but their reliability as world simulators depends on whether they capture physical, logical, and spatial constraints. Existing metrics such as Frechet Video Distance (FVD) emphasize perceptual quality and overlook reasoning failures, including violations of causality, physics, and global consistency. We introduce MMGR (Multi-Modal Generative Reasoning Evaluation and Benchmark), a principled evaluation framework based on five reasoning abilities: Physical, Logical, 3D Spatial, 2D Spatial, and Temporal. MMGR evaluates generative reasoning across three domains: Abstract Reasoning (ARC-AGI, Sudoku), Embodied Navigation (real-world 3D navigation and localization), and Physical Commonsense (sports and compositional interactions). MMGR applies fine-grained metrics that require holistic correctness across both video and image generation. We benchmark leading video models (Veo-3, Sora-2, Wan-2.2) and image models (Nano-banana, Nano-banana Pro, GPT-4o-image, Qwen-image), revealing strong performance gaps across domains. Models show moderate success on Physical Commonsense tasks but perform poorly on Abstract Reasoning (below 10 percent accuracy on ARC-AGI) and struggle with long-horizon spatial planning in embodied settings. Our analysis highlights key limitations in current models, including overreliance on perceptual data, weak global state consistency, and objectives that reward visual plausibility over causal correctness. MMGR offers a unified diagnostic benchmark and a path toward reasoning-aware generative world models.

The prevailing video retrieval paradigm is structurally misaligned, as narrow benchmarks incentivize correspondingly limited data and single-task training. Therefore, universal capability is suppressed due to the absence of a diagnostic evaluation that defines and demands multi-dimensional generalization. To break this cycle, we introduce a framework built on the co-design of evaluation, data, and modeling. First, we establish the Universal Video Retrieval Benchmark (UVRB), a suite of 16 datasets designed not only to measure performance but also to diagnose critical capability gaps across tasks and domains. Second, guided by UVRB's diagnostics, we introduce a scalable synthesis workflow that generates 1.55 million high-quality pairs to populate the semantic space required for universality. Finally, we devise the Modality Pyramid, a curriculum that trains our General Video Embedder (GVE) by explicitly leveraging the latent interconnections within our diverse data. Extensive experiments show GVE achieves state-of-the-art zero-shot generalization on UVRB. In particular, our analysis reveals that popular benchmarks are poor predictors of general ability and that partially relevant retrieval is a dominant but overlooked scenario. Overall, our co-designed framework provides a practical path to escape the limited scope and advance toward truly universal video retrieval.

Modern language models capture a large body of factual knowledge. However, some facts can be incorrectly induced or become obsolete over time, resulting in factually incorrect generations. This has led to the development of various editing methods that allow updating facts encoded by the model. Evaluation of these methods has primarily focused on testing whether an individual fact has been successfully injected, and if similar predictions for other subjects have not changed. Here we argue that such evaluation is limited, since injecting one fact (e.g. ``Jack Depp is the son of Johnny Depp'') introduces a ``ripple effect'' in the form of additional facts that the model needs to update (e.g.``Jack Depp is the sibling of Lily-Rose Depp''). To address this issue, we propose a novel set of evaluation criteria that consider the implications of an edit on related facts. Using these criteria, we then construct , a diagnostic benchmark of 5K factual edits, capturing a variety of types of ripple effects. We evaluate prominent editing methods on , showing that current methods fail to introduce consistent changes in the model's knowledge. In addition, we find that a simple in-context editing baseline obtains the best scores on our benchmark, suggesting a promising research direction for model editing.

We describe WebSuite, the first diagnostic benchmark for generalist web agents, designed to systematically evaluate why agents fail. Advances in AI have led to the rise of numerous web agents that autonomously operate a browser to complete tasks. However, most existing benchmarks focus on strictly measuring whether an agent can or cannot complete a task, without giving insight on why. In this paper, we 1) develop a taxonomy of web actions to facilitate identifying common failure patterns, and 2) create an extensible benchmark suite to assess agents' performance on our taxonomized actions. This benchmark suite consists of both individual tasks, such as clicking a button, and end-to-end tasks, such as adding an item to a cart, and is designed such that any failure of a task can be attributed directly to a failure of a specific web action. We evaluate two popular generalist web agents, one text-based and one multimodal, and identify unique weaknesses for each agent. Because WebSuite can disaggregate task failures into specific action failures, this enables granular identification of which UX flows an individual agent has trouble with and immediately highlights promising avenues for improvement. These findings highlight the need for more focused benchmarking on where web agents go wrong to effectively improve agents beyond their weaker performance today.

Deep Research Agents are increasingly used for automated survey generation. However, whether they can write surveys like human experts remains unclear. Existing benchmarks focus on fluency or citation accuracy, but none evaluates the core capabilities: retrieving essential papers and organizing them into coherent knowledge structures. We introduce TaxoBench, a diagnostic benchmark derived from 72 highly-cited computer science surveys. We manually extract expert-authored taxonomy trees containing 3,815 precisely categorized citations as ground truth. Our benchmark supports two evaluation modes: Deep Research mode tests end-to-end retrieval and organization given only a topic, while Bottom-Up mode isolates structuring capability by providing the exact papers human experts used. We evaluate 7 leading Deep Research agents and 12 frontier LLMs. Results reveal a dual bottleneck: the best agent recalls only 20.9% of expert-selected papers, and even with perfect input, the best model achieves only 0.31 ARI in organization. Current deep research agents remain far from expert-level survey writing. Our benchmark is publicly available at https://github.com/KongLongGeFDU/TaxoBench.

Punctuation plays a critical role in resolving semantic and structural ambiguity in written language. Machine Translation (MT) systems are now widely applied across diverse domains and languages, including many low-resource settings. In this work, we focus on Marathi, a low- to middle-resource language. We introduce Virām, the first diagnostic benchmark for assessing punctuation robustness in English-to-Marathi machine translation, consisting of 54 manually curated, punctuation-ambiguous instances. We evaluate two primary strategies for enhancing reliability: a pipeline-based restore-then-translate approach and direct fine-tuned on punctuation-varied data. Our results demonstrate that specialized fine-tuned models and pipeline systems significantly improve translation quality over standard baselines on the Virām benchmark. Qualitative analysis reveals that the original model may result in wrong translations leading to wrong interpretations, while fine-tuned models significantly improve overall reliability. Furthermore, we find that current Large Language Models (LLMs) lag behind these task-specific approaches in preserving meaning for punctuation-ambiguous text, thus necessitating further research in this area. The code and dataset is available at https://github.com/KaustubhShejole/Viram_Marathi.

The evaluation of Retrieval-Augmented Generation (RAG) systems typically examines retrieval quality and generation parameters like temperature in isolation, overlooking their interaction. This work presents a systematic investigation of how text perturbations (simulating noisy retrieval) interact with temperature settings across multiple LLM runs. We propose a comprehensive RAG Perturbation-Temperature Analysis Framework that subjects retrieved documents to three distinct perturbation types across varying temperature settings. Through extensive experiments on HotpotQA with both open-source and proprietary LLMs, we demonstrate that performance degradation follows distinct patterns: high-temperature settings consistently amplify vulnerability to perturbations, while certain perturbation types exhibit non-linear sensitivity across the temperature range. Our work yields three key contributions: (1) a diagnostic benchmark for assessing RAG robustness, (2) an analytical framework for quantifying perturbation-temperature interactions, and (3) practical guidelines for model selection and parameter tuning under noisy retrieval conditions.

This paper investigates the rational thinking capability of Large Language Models (LLMs) in multi-round argumentative debates by exploring the impact of fallacious arguments on their logical reasoning performance. More specifically, we present Logic Competence Measurement Benchmark (LOGICOM), a diagnostic benchmark to assess the robustness of LLMs against logical fallacies. LOGICOM involves two agents: a persuader and a debater engaging in a multi-round debate on a controversial topic, where the persuader tries to convince the debater of the correctness of its claim. First, LOGICOM assesses the potential of LLMs to change their opinions through reasoning. Then, it evaluates the debater's performance in logical reasoning by contrasting the scenario where the persuader employs logical fallacies against one where logical reasoning is used. We use this benchmark to evaluate the performance of GPT-3.5 and GPT-4 using a dataset containing controversial topics, claims, and reasons supporting them. Our findings indicate that both GPT-3.5 and GPT-4 can adjust their opinion through reasoning. However, when presented with logical fallacies, GPT-3.5 and GPT-4 are erroneously convinced 41% and 69% more often, respectively, compared to when logical reasoning is used. Finally, we introduce a new dataset containing over 5k pairs of logical vs. fallacious arguments. The source code and dataset of this work are made publicly available.

Test-time compute has empowered multimodal large language models to generate extended reasoning chains, yielding strong performance on tasks such as multimodal math reasoning. However, this improved reasoning ability often comes with increased hallucination: as generations become longer, models tend to drift away from image-grounded content and rely more heavily on language priors. Attention analysis shows that longer reasoning chains lead to reduced focus on visual inputs, which contributes to hallucination. To systematically study this phenomenon, we introduce RH-AUC, a metric that quantifies how a model's perception accuracy changes with reasoning length, allowing us to evaluate whether the model preserves visual grounding during reasoning. We also release RH-Bench, a diagnostic benchmark that spans a variety of multimodal tasks, designed to assess the trade-off between reasoning ability and hallucination. Our analysis reveals that (i) larger models typically achieve a better balance between reasoning and perception, and (ii) this balance is influenced more by the types and domains of training data than by its overall volume. These findings underscore the importance of evaluation frameworks that jointly consider both reasoning quality and perceptual fidelity.

Low-rank adaptation (LoRA) has become a standard tool for efficiently fine-tuning large language models (LLMs). Yet, even minor LoRA updates can induce alignment drift, weakening safety and behavioral constraints through entangled parameter changes. To address this, we propose AlignGuard-LoRA (AGL), a principled framework for preserving alignment during finetuning. AGL introduces several key components: a primary task loss for supervision, Fisher Information Matrix-based regularization to restrict updates in alignment-sensitive subspaces, and task-specific regularization to stabilize the integration of new knowledge. We further introduce collision-aware regularization, blending Riemannian overlap -- which penalizes coordinate-wise interference -- and geodesic separation -- which encourages disjoint update geometry. We curate DriftCaps, a targeted diagnostic benchmark of safe and unsafe prompts designed to quantify alignment drift and safety degradation. Empirical evaluations show that AGL mitigates alignment drift by up to 50% on safety-critical benchmarks without degrading downstream task performance. Comprehensive ablation confirms that each component contributes distinctly to preserving latent safety behaviors. Finally, we derive and validate a scaling law for catastrophic forgetting, revealing that AGL flattens post-finetuning loss escalation while preserving adaptation dynamics. AGL is a structurally grounded refinement of LoRA, ensuring alignment preservation with minimal trade-offs. To encourage further exploration and development, we open-source our implementation.

Understanding the fine-grained articulation of human hands is critical in high-stakes settings such as robot-assisted surgery, chip manufacturing, and AR/VR-based human-AI interaction. Despite achieving near-human performance on general vision-language benchmarks, current vision-language models (VLMs) struggle with fine-grained spatial reasoning, especially in interpreting complex and articulated hand poses. We introduce HandVQA, a large-scale diagnostic benchmark designed to evaluate VLMs' understanding of detailed hand anatomy through visual question answering. Built upon high-quality 3D hand datasets (FreiHAND, InterHand2.6M, FPHA), our benchmark includes over 1.6M controlled multiple-choice questions that probe spatial relationships between hand joints, such as angles, distances, and relative positions. We evaluate several state-of-the-art VLMs (LLaVA, DeepSeek and Qwen-VL) in both base and fine-tuned settings, using lightweight fine-tuning via LoRA. Our findings reveal systematic limitations in current models, including hallucinated finger parts, incorrect geometric interpretations, and poor generalization. HandVQA not only exposes these critical reasoning gaps but provides a validated path to improvement. We demonstrate that the 3D-grounded spatial knowledge learned from our benchmark transfers in a zero-shot setting, significantly improving accuracy of model on novel downstream tasks like hand gesture recognition (+10.33%) and hand-object interaction (+2.63%).

Automatic speech recognition (ASR) systems have achieved near-human accuracy on curated benchmarks, yet still fail in real-world voice agents under conditions that current evaluations do not systematically cover. Without diagnostic tools that isolate specific failure factors, practitioners cannot anticipate which conditions, in which languages, will cause what degree of degradation. We introduce WildASR, a multilingual (four-language) diagnostic benchmark sourced entirely from real human speech that factorizes ASR robustness along three axes: environmental degradation, demographic shift, and linguistic diversity. Evaluating seven widely used ASR systems, we find severe and uneven performance degradation, and model robustness does not transfer across languages or conditions. Critically, models often hallucinate plausible but unspoken content under partial or degraded inputs, creating concrete safety risks for downstream agent behavior. Our results demonstrate that targeted, factor-isolated evaluation is essential for understanding and improving ASR reliability in production systems. Besides the benchmark itself, we also present three analytical tools that practitioners can use to guide deployment decisions.

We present SpinBench, a cognitively grounded diagnostic benchmark for evaluating spatial reasoning in vision language models (VLMs). SpinBench is designed around the core challenge of spatial reasoning: perspective taking, the ability to reason about how scenes and object relations change under viewpoint transformation. Since perspective taking requires multiple cognitive capabilities, such as recognizing objects across views, relative positions grounding, and mentally simulating transformations, SpinBench introduces a set of fine-grained diagnostic categories. Our categories target translation, rotation, object relative pose, and viewpoint change, and are progressively structured so that single-object simpler tasks scaffold toward the most demanding multi-object perspective-taking setting. We evaluate 37 state-of-the-art VLMs, both proprietary and open source. Results reveal systematic weaknesses: strong egocentric bias, poor rotational understanding, and inconsistencies under symmetrical and syntactic reformulations. Scaling analysis shows both smooth improvements and emergent capabilities. While human subjects achieve high accuracy (91.2\%), task difficulty as measured by human response time shows strong correlation with VLM accuracy, indicating that SpinBench captures spatial reasoning challenges shared across humans and VLMs. We believe SpinBench provides critical insights into spatial reasoning in VLMs and highlights key gaps in their ability to reason about physical space. Our website can be found at https://spinbench25.github.io/.

Vision-Language Models (VLMs) have demonstrated impressive capabilities in understanding visual content, but their reliability in safety-critical contexts remains under-explored. We introduce VERI (Visual Emergency Recognition Dataset), a carefully designed diagnostic benchmark of 200 images (100 contrastive pairs). Each emergency scene is matched with a visually similar but safe counterpart through multi-stage human verification and iterative refinement. Using a two-stage protocol - risk identification and emergency response - we evaluate 14 VLMs (2B-124B parameters) across medical emergencies, accidents, and natural disasters. Our analysis reveals a systematic overreaction problem: models excel at identifying real emergencies (70-100 percent success rate) but suffer from an alarming rate of false alarms, misidentifying 31-96 percent of safe situations as dangerous, with 10 scenarios failed by all models regardless of scale. This "better-safe-than-sorry" bias manifests primarily through contextual overinterpretation (88-93 percent of errors), challenging VLMs' reliability for safety applications. These findings highlight persistent limitations that are not resolved by increasing model scale, motivating targeted approaches for improving contextual safety assessment in visually misleading scenarios.

Current robotic evaluation is still largely dominated by binary success rates, which collapse rich execution processes into a single outcome and obscure critical qualities such as progress, efficiency, and stability. To address this limitation, we propose PRM-as-a-Judge, a dense evaluation paradigm that leverages Process Reward Models (PRMs) to audit policy execution directly from trajectory videos by estimating task progress from observation sequences. Central to this paradigm is the OPD (Outcome-Process-Diagnosis) metric system, which explicitly formalizes execution quality via a task-aligned progress potential. We characterize dense robotic evaluation through two axiomatic properties: macro-consistency, which requires additive and path-consistent aggregation, and micro-resolution, which requires sensitivity to fine-grained physical evolution. Under this formulation, potential-based PRM judges provide a natural instantiation of dense evaluation, with macro-consistency following directly from the induced scalar potential. We empirically validate the micro-resolution property using RoboPulse, a diagnostic benchmark specifically designed for probing micro-scale progress discrimination, where several trajectory-trained PRM judges outperform discriminative similarity-based methods and general-purpose foundation-model judges. Finally, leveraging PRM-as-a-Judge and the OPD metric system, we conduct a structured audit of mainstream policy paradigms across long-horizon tasks, revealing behavioral signatures and failure modes that are invisible to outcome-only metrics.

Spatial reasoning is a core component of human cognition, enabling individuals to perceive, comprehend, and interact with the physical world. It relies on a nuanced understanding of spatial structures and inter-object relationships, serving as the foundation for complex reasoning and decision-making. To investigate whether current vision-language models (VLMs) exhibit similar capability, we introduce Jigsaw-Puzzles, a novel benchmark consisting of 1,100 carefully curated real-world images with high spatial complexity. Based on this dataset, we design five tasks to rigorously evaluate VLMs' spatial perception, structural understanding, and reasoning capabilities, while deliberately minimizing reliance on domain-specific knowledge to better isolate and assess the general spatial reasoning capability. We conduct a comprehensive evaluation across 24 state-of-the-art VLMs. The results show that even the strongest model, Gemini-2.5-Pro, achieves only 77.14% overall accuracy and performs particularly poorly on the Order Generation task, with only 30.00% accuracy, far below the performance exceeding 90% achieved by human participants. This persistent gap underscores the need for continued progress, positioning Jigsaw-Puzzles as a challenging and diagnostic benchmark for advancing spatial reasoning research in VLMs.

Cyclists often encounter safety-critical situations in urban traffic, highlighting the need for assistive systems that support safe and informed decision-making. Recently, vision-language models (VLMs) have demonstrated strong performance on autonomous driving benchmarks, suggesting their potential for general traffic understanding and navigation-related reasoning. However, existing evaluations are predominantly vehicle-centric and fail to assess perception and reasoning from a cyclist-centric viewpoint. To address this gap, we introduce CyclingVQA, a diagnostic benchmark designed to probe perception, spatio-temporal understanding, and traffic-rule-to-lane reasoning from a cyclist's perspective. Evaluating 31+ recent VLMs spanning general-purpose, spatially enhanced, and autonomous-driving-specialized models, we find that current models demonstrate encouraging capabilities, while also revealing clear areas for improvement in cyclist-centric perception and reasoning, particularly in interpreting cyclist-specific traffic cues and associating signs with the correct navigational lanes. Notably, several driving-specialized models underperform strong generalist VLMs, indicating limited transfer from vehicle-centric training to cyclist-assistive scenarios. Finally, through systematic error analysis, we identify recurring failure modes to guide the development of more effective cyclist-assistive intelligent systems.

Although Large Audio-Language Models (LALMs) deliver state-of-the-art (SOTA) performance, they frequently suffer from hallucinations, e.g. generating text not grounded in the audio input. We analyze these grounding failures and identify a distinct taxonomy: Event Omission, False Event Identity, Temporal Relation Error, and Quantitative Temporal Error. To address this, we introduce the AHA (Audio Hallucination Alignment) framework. By leveraging counterfactual hard negative mining, our pipeline constructs a high-quality preference dataset that forces models to distinguish strict acoustic evidence from linguistically plausible fabrications. Additionally, we establish AHA-Eval, a diagnostic benchmark designed to rigorously test these fine-grained temporal reasoning capabilities. We apply this data to align Qwen2.5-Omni. The resulting model, Qwen-Audio-AHA, achieves a 13.7% improvement on AHA-Eval. Crucially, this benefit generalizes beyond our diagnostic set. Our model shows substantial gains on public benchmarks, including 1.3% on MMAU-Test and 1.6% on MMAR, outperforming latest SOTA methods.

Models like OpenAI-o3 pioneer visual grounded reasoning by dynamically referencing visual regions, just like human "thinking with images". However, no benchmark exists to evaluate these capabilities holistically. To bridge this gap, we propose TreeBench (Traceable Evidence Evaluation Benchmark), a diagnostic benchmark built on three principles: (1) focused visual perception of subtle targets in complex scenes, (2) traceable evidence via bounding box evaluation, and (3) second-order reasoning to test object interactions and spatial hierarchies beyond simple object localization. Prioritizing images with dense objects, we initially sample 1K high-quality images from SA-1B, and incorporate eight LMM experts to manually annotate questions, candidate options, and answers for each image. After three stages of quality control, TreeBench consists of 405 challenging visual question-answering pairs, even the most advanced models struggle with this benchmark, where none of them reach 60% accuracy, e.g., OpenAI-o3 scores only 54.87. Furthermore, we introduce TreeVGR (Traceable Evidence Enhanced Visual Grounded Reasoning), a training paradigm to supervise localization and reasoning jointly with reinforcement learning, enabling accurate localizations and explainable reasoning pathways. Initialized from Qwen2.5-VL-7B, it improves V* Bench (+16.8), MME-RealWorld (+12.6), and TreeBench (+13.4), proving traceability is key to advancing vision-grounded reasoning. The code is available at https://github.com/Haochen-Wang409/TreeVGR.

Coworking AI agents operating within local file systems are rapidly emerging as a paradigm in human-AI interaction; however, effective personalization remains limited by severe data constraints, as strict privacy barriers and the difficulty of jointly collecting multimodal real-world traces prevent scalable training and evaluation, and existing methods remain interaction-centric while overlooking dense behavioral traces in file-system operations; to address this gap, we propose FileGram, a comprehensive framework that grounds agent memory and personalization in file-system behavioral traces, comprising three core components: (1) FileGramEngine, a scalable persona-driven data engine that simulates realistic workflows and generates fine-grained multimodal action sequences at scale; (2) FileGramBench, a diagnostic benchmark grounded in file-system behavioral traces for evaluating memory systems on profile reconstruction, trace disentanglement, persona drift detection, and multimodal grounding; and (3) FileGramOS, a bottom-up memory architecture that builds user profiles directly from atomic actions and content deltas rather than dialogue summaries, encoding these traces into procedural, semantic, and episodic channels with query-time abstraction; extensive experiments show that FileGramBench remains challenging for state-of-the-art memory systems and that FileGramEngine and FileGramOS are effective, and by open-sourcing the framework, we hope to support future research on personalized memory-centric file-system agents.

Reinforcement learning (RL) has shown great effectiveness for fine-tuning large language models (LLMs) using tasks that are challenging yet easily verifiable, such as math reasoning or code generation. However, extending this success to visual perception in vision-language models (VLMs) has been impeded by the scarcity of vision-centric tasks that are simultaneously challenging and unambiguously verifiable. To this end, we introduce ViCrit (Visual Caption Hallucination Critic), an RL proxy task that trains VLMs to localize a subtle, synthetic visual hallucination injected into paragraphs of human-written image captions. Starting from a 200-word captions, we inject a single, subtle visual description error-altering a few words on objects, attributes, counts, or spatial relations-and task the model to pinpoint the corrupted span given the image and the modified caption. This formulation preserves the full perceptual difficulty while providing a binary, exact-match reward that is easy to compute and unambiguous. Models trained with the ViCrit Task exhibit substantial gains across a variety of VL benchmarks. Crucially, the improvements transfer beyond natural-image training data to abstract image reasoning and visual math, showing promises of learning to perceive rather than barely memorizing seen objects. To facilitate evaluation, we further introduce ViCrit-Bench, a category-balanced diagnostic benchmark that systematically probes perception errors across diverse image domains and error types. Together, our results demonstrate that fine-grained hallucination criticism is an effective and generalizable objective for enhancing visual perception in VLMs.

Understanding visual scenes is fundamental to human intelligence. While discriminative models have significantly advanced computer vision, they often struggle with compositional understanding. In contrast, recent generative text-to-image diffusion models excel at synthesizing complex scenes, suggesting inherent compositional capabilities. Building on this, zero-shot diffusion classifiers have been proposed to repurpose diffusion models for discriminative tasks. While prior work offered promising results in discriminative compositional scenarios, these results remain preliminary due to a small number of benchmarks and a relatively shallow analysis of conditions under which the models succeed. To address this, we present a comprehensive study of the discriminative capabilities of diffusion classifiers on a wide range of compositional tasks. Specifically, our study covers three diffusion models (SD 1.5, 2.0, and, for the first time, 3-m) spanning 10 datasets and over 30 tasks. Further, we shed light on the role that target dataset domains play in respective performance; to isolate the domain effects, we introduce a new diagnostic benchmark Self-Bench comprised of images created by diffusion models themselves. Finally, we explore the importance of timestep weighting and uncover a relationship between domain gap and timestep sensitivity, particularly for SD3-m. To sum up, diffusion classifiers understand compositionality, but conditions apply! Code and dataset are available at https://github.com/eugene6923/Diffusion-Classifiers-Compositionality.

As video content creation shifts toward long-form narratives, composing short clips into coherent storylines becomes increasingly important. However, prevailing retrieval formulations remain context-agnostic at inference time, prioritizing local semantic alignment while neglecting state and identity consistency. To address this structural limitation, we formalize the task of Consistent Video Retrieval (CVR) and introduce a diagnostic benchmark spanning YouCook2, COIN, and CrossTask. We propose CAST (Context-Aware State Transition), a lightweight, plug-and-play adapter compatible with diverse frozen vision-language embedding spaces. By predicting a state-conditioned residual update (Δ) from visual history, CAST introduces an explicit inductive bias for latent state evolution. Extensive experiments show that CAST improves performance on YouCook2 and CrossTask, remains competitive on COIN, and consistently outperforms zero-shot baselines across diverse foundation backbones. Furthermore, CAST provides a useful reranking signal for black-box video generation candidates (e.g., from Veo), promoting more temporally coherent continuations.

Spatial intelligence is a critical frontier for Multimodal Large Language Models (MLLMs), empowering them to comprehend the physical world. Drawing inspiration from human perception mechanisms, existing studies attempt to construct a coherent spatial understanding via grid-based cognitive maps from multi-frame visual inputs. However, current grid-based map methods rely on discretized raster representations, which limit the model's ability in fine-grained spatial reasoning. To overcome this limitation, we propose Video2Layout, a framework for reconstructing metric-grounded spatial layouts from video. The framework employs continuous object boundary coordinates to quantify inter-object physical distances and object size. This empowers the model with quantitative spatial computation capabilities, effectively alleviating the inherent ambiguity when describing spatial relationships in natural language. Specifically, our method comprises two core stages. First, in supervised fine-tuning stage, we construct a high-quality dataset from the AI2THOR simulator, which enables the model to learn the mapping from visual inputs to precise boundary coordinates. Subsequently, a reinforcement fine-tuning stage further enhances the model's real-world generalization capabilities. To systematically evaluate the correlation between cognitive map accuracy and image quantity, as well as how the quantity of image inputs affects spatial reasoning accuracy, we introduce QVS-Bench, a diagnostic benchmark designed to analyze the relevant mechanisms. Evaluated on QVS-Bench and mainstream spatial reasoning benchmarks, our model, V2LO-7B achieves an average improvement of 4.92% over the model trained on grid maps, validating the superiority of our method. Our code is available at https://github.com/ybrrraway/Video2Layout.

Long-context LLMs and Retrieval-Augmented Generation (RAG) systems process information passively, deferring state tracking, contradiction resolution, and evidence aggregation to query time, which becomes brittle under ultra long streams with frequent updates. We propose the Unified Memory Agent (UMA), an end-to-end reinforcement learning framework that unifies memory operations and question answering within a single policy. UMA maintains a dual memory representation: a compact core summary for global context and a structured Memory Bank that supports explicit CRUD (create, update, delete, reorganize) over key value entries, enabling proactive consolidation during streaming. To evaluate long-horizon memory behavior, we introduce Ledger-QA, a diagnostic benchmark for continuous state tracking where answers are latent values derived from accumulated updates rather than lo cal span retrieval. Across 13 datasets spanning Ledger-QA, Test-Time Learning, and Accurate Retrieval, UMA substantially outperforms long-context and RAG baselines on dynamic reasoning and learning tasks while remaining competitive on standard retrieval benchmarks, underscoring the importance of learned, end-to-end memory management.

Recent advances in reasoning-centric models promise improved robustness through mechanisms such as chain-of-thought prompting and test-time scaling. However, their ability to withstand misleading user input remains underexplored. In this paper, we conduct a systematic evaluation of three state-of-the-art reasoning models, i.e., OpenAI's o4-mini, Claude-3.7-Sonnet and Gemini-2.5-Flash, across three multimodal benchmarks: MMMU, MathVista, and CharXiv. Our evaluation reveals significant accuracy drops (25-29% on average) following gaslighting negation prompts, indicating that even top-tier reasoning models struggle to preserve correct answers under manipulative user feedback. Built upon the insights of the evaluation and to further probe this vulnerability, we introduce GaslightingBench-R, a new diagnostic benchmark specifically designed to evaluate reasoning models' susceptibility to defend their belief under gaslighting negation prompt. Constructed by filtering and curating 1,025 challenging samples from the existing benchmarks, GaslightingBench-R induces even more dramatic failures, with accuracy drops exceeding 53% on average. Our findings reveal fundamental limitations in the robustness of reasoning models, highlighting the gap between step-by-step reasoning and belief persistence.

Tasks such as solving arithmetic equations, evaluating truth tables, and completing syllogisms are handled well by large language models (LLMs) in their standard form, but they often fail when the same problems are posed in logically equivalent yet obfuscated formats. To study this vulnerability, we introduce Logifus, a structure-preserving logical obfuscation framework, and, utilizing this, we present LogiQAte, a first-of-its-kind diagnostic benchmark with 1,108 questions across four reasoning tasks: (i) Obfus FOL (first-order logic entailment under equivalence-preserving rewrites), (ii) Obfus Blood Relation (family-graph entailment under indirect relational chains), (iii) Obfus Number Series (pattern induction under symbolic substitutions), and (iv) Obfus Direction Sense (navigation reasoning under altered directions and reference frames). Across all the tasks, evaluating six state-of-the-art models, we find that obfuscation severely degrades zero-shot performance, with performance dropping on average by 47% for GPT-4o, 27% for GPT-5, and 22% for reasoning model, o4-mini. Our findings reveal that current LLMs parse questions without deep understanding, highlighting the urgency of building models that genuinely comprehend and preserve meaning beyond surface form.

Compared to single-turn dialogue, multi-turn dialogue involving multiple images better aligns with the needs of real-world human-AI interactions. Additionally, as training data, it provides richer contextual reasoning information, thereby guiding the model to achieve better performance. However, existing vision-language models (VLMs) primarily rely on single-turn dialogue training and evaluation benchmarks. In this paper, following the characteristics of human dialogue, such as focused topics and concise, clear content, we present MMCR (Multimodal Multi-turn Contextual Reasoning), a novel dataset comprising: (1) MMCR-310k -- the largest multi-image multi-turn instruction tuning dataset with 310K contextual dialogues, each covering 1-4 images and 4 or 8 dialogue turns; and (2) MMCR-Bench -- a diagnostic benchmark featuring dialogues, spanning 8 domains (Humanities, Natural, Science, Education, etc.) and 40 sub-topics. Extensive evaluations demonstrate that models fine-tuned with MMCR-310k achieve 5.2\% higher contextual accuracy on MMCR-Bench, while showing consistent improvements on existing benchmarks (+1.1\% on AI2D, +1.2\% on MMMU and MMVet). MMCR and prompt engineering will be released publicly.

Quantitative evaluation has increased dramatically among recent video inpainting work, but the video and mask content used to gauge performance has received relatively little attention. Although attributes such as camera and background scene motion inherently change the difficulty of the task and affect methods differently, existing evaluation schemes fail to control for them, thereby providing minimal insight into inpainting failure modes. To address this gap, we propose the Diagnostic Evaluation of Video Inpainting on Landscapes (DEVIL) benchmark, which consists of two contributions: (i) a novel dataset of videos and masks labeled according to several key inpainting failure modes, and (ii) an evaluation scheme that samples slices of the dataset characterized by a fixed content attribute, and scores performance on each slice according to reconstruction, realism, and temporal consistency quality. By revealing systematic changes in performance induced by particular characteristics of the input content, our challenging benchmark enables more insightful analysis into video inpainting methods and serves as an invaluable diagnostic tool for the field. Our code and data are available at https://github.com/MichiganCOG/devil .

Neural text-to-SQL models have achieved remarkable performance in translating natural language questions into SQL queries. However, recent studies reveal that text-to-SQL models are vulnerable to task-specific perturbations. Previous curated robustness test sets usually focus on individual phenomena. In this paper, we propose a comprehensive robustness benchmark based on Spider, a cross-domain text-to-SQL benchmark, to diagnose the model robustness. We design 17 perturbations on databases, natural language questions, and SQL queries to measure the robustness from different angles. In order to collect more diversified natural question perturbations, we utilize large pretrained language models (PLMs) to simulate human behaviors in creating natural questions. We conduct a diagnostic study of the state-of-the-art models on the robustness set. Experimental results reveal that even the most robust model suffers from a 14.0% performance drop overall and a 50.7% performance drop on the most challenging perturbation. We also present a breakdown analysis regarding text-to-SQL model designs and provide insights for improving model robustness.

How can we test AI performance? This question seems trivial, but it isn't. Standard benchmarks often have problems such as in-distribution and small-size test sets, oversimplified metrics, unfair comparisons, and short-term outcome pressure. As a consequence, good performance on standard benchmarks does not guarantee success in real-world scenarios. To address these problems, we present Touchstone, a large-scale collaborative segmentation benchmark of 9 types of abdominal organs. This benchmark is based on 5,195 training CT scans from 76 hospitals around the world and 5,903 testing CT scans from 11 additional hospitals. This diverse test set enhances the statistical significance of benchmark results and rigorously evaluates AI algorithms across various out-of-distribution scenarios. We invited 14 inventors of 19 AI algorithms to train their algorithms, while our team, as a third party, independently evaluated these algorithms on three test sets. In addition, we also evaluated pre-existing AI frameworks--which, differing from algorithms, are more flexible and can support different algorithms--including MONAI from NVIDIA, nnU-Net from DKFZ, and numerous other open-source frameworks. We are committed to expanding this benchmark to encourage more innovation of AI algorithms for the medical domain.

Benchmarking competitions are central to the development of artificial intelligence (AI) in medical imaging, defining performance standards and shaping methodological progress. However, it remains unclear whether these benchmarks provide data that are sufficiently representative, accessible, and reusable to support clinically meaningful AI. In this work, we assess fairness along two complementary dimensions: (1) whether challenge datasets are representative of real-world clinical diversity, and (2) whether they are accessible and legally reusable in line with the FAIR principles. To address this question, we conducted a large-scale systematic study of 241 biomedical image analysis challenges comprising 458 tasks across 19 imaging modalities. Our findings show substantial biases in dataset composition, including geographic location, modality-, and problem type-related biases, indicating that current benchmarks do not adequately reflect real-world clinical diversity. Despite their widespread influence, challenge datasets were frequently constrained by restrictive or ambiguous access conditions, inconsistent or non-compliant licensing practices, and incomplete documentation, limiting reproducibility and long-term reuse. Together, these shortcomings expose foundational fairness limitations in our benchmarking ecosystem and highlight a disconnect between leaderboard success and clinical relevance.

Medical benchmarks are indispensable for evaluating the capabilities of language models in healthcare for non-English-speaking communities,therefore help ensuring the quality of real-life applications. However, not every community has sufficient resources and standardized methods to effectively build and design such benchmark, and available non-English medical data is normally fragmented and difficult to verify. We developed an approach to tackle this problem and applied it to create the first Vietnamese medical question benchmark, featuring 14,000 multiple-choice questions across 34 medical specialties. Our benchmark was constructed using various verifiable sources, including carefully curated medical exams and clinical records, and eventually annotated by medical experts. The benchmark includes four difficulty levels, ranging from foundational biological knowledge commonly found in textbooks to typical clinical case studies that require advanced reasoning. This design enables assessment of both the breadth and depth of language models' medical understanding in the target language thanks to its extensive coverage and in-depth subject-specific expertise. We release the benchmark in three parts: a sample public set (4k questions), a full public set (10k questions), and a private set (2k questions) used for leaderboard evaluation. Each set contains all medical subfields and difficulty levels. Our approach is scalable to other languages, and we open-source our data construction pipeline to support the development of future multilingual benchmarks in the medical domain.

Vision-Language Models (VLMs) have demonstrated remarkable progress in multimodal understanding, yet their capabilities for scientific reasoning remains inadequately assessed. Current multimodal benchmarks predominantly evaluate generic image comprehension or text-driven reasoning, lacking authentic scientific contexts that require domain-specific knowledge integration with visual evidence analysis. To fill this gap, we present CSVQA, a diagnostic multimodal benchmark specifically designed for evaluating scientific reasoning through domain-grounded visual question answering.Our benchmark features 1,378 carefully constructed question-answer pairs spanning diverse STEM disciplines, each demanding domain knowledge, integration of visual evidence, and higher-order reasoning. Compared to prior multimodal benchmarks, CSVQA places greater emphasis on real-world scientific content and complex reasoning.We additionally propose a rigorous evaluation protocol to systematically assess whether model predictions are substantiated by valid intermediate reasoning steps based on curated explanations. Our comprehensive evaluation of 15 VLMs on this benchmark reveals notable performance disparities, as even the top-ranked proprietary model attains only 49.6\% accuracy.This empirical evidence underscores the pressing need for advancing scientific reasoning capabilities in VLMs. Our CSVQA is released at https://huggingface.co/datasets/Skywork/CSVQA.

Medical benchmark datasets significantly contribute to developing Large Language Models (LLMs) for medical knowledge extraction, diagnosis, summarization, and other uses. Yet, current benchmarks are mainly derived from exam questions given to medical students or cases described in the medical literature, lacking the complexity of real-world patient cases that deviate from classic textbook abstractions. These include rare diseases, uncommon presentations of common diseases, and unexpected treatment responses. Here, we construct Clinically Uncommon Patient Cases and Diagnosis Dataset (CUPCase) based on 3,562 real-world case reports from BMC, including diagnoses in open-ended textual format and as multiple-choice options with distractors. Using this dataset, we evaluate the ability of state-of-the-art LLMs, including both general-purpose and Clinical LLMs, to identify and correctly diagnose a patient case, and test models' performance when only partial information about cases is available. Our findings show that general-purpose GPT-4o attains the best performance in both the multiple-choice task (average accuracy of 87.9%) and the open-ended task (BERTScore F1 of 0.764), outperforming several LLMs with a focus on the medical domain such as Meditron-70B and MedLM-Large. Moreover, GPT-4o was able to maintain 87% and 88% of its performance with only the first 20% of tokens of the case presentation in multiple-choice and free text, respectively, highlighting the potential of LLMs to aid in early diagnosis in real-world cases. CUPCase expands our ability to evaluate LLMs for clinical decision support in an open and reproducible manner.

The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static knowledge, failing to capture the dynamic, application-oriented capabilities required in clinical practice. To bridge this gap, we introduce a Medical LLM Benchmark MLB, a comprehensive benchmark evaluating LLMs on both foundational knowledge and scenario-based reasoning. MLB is structured around five core dimensions: Medical Knowledge (MedKQA), Safety and Ethics (MedSE), Medical Record Understanding (MedRU), Smart Services (SmartServ), and Smart Healthcare (SmartCare). The benchmark integrates 22 datasets (17 newly curated) from diverse Chinese clinical sources, covering 64 clinical specialties. Its design features a rigorous curation pipeline involving 300 licensed physicians. Besides, we provide a scalable evaluation methodology, centered on a specialized judge model trained via Supervised Fine-Tuning (SFT) on expert annotations. Our comprehensive evaluation of 10 leading models reveals a critical translational gap: while the top-ranked model, Kimi-K2-Instruct (77.3% accuracy overall), excels in structured tasks like information extraction (87.8% accuracy in MedRU), performance plummets in patient-facing scenarios (61.3% in SmartServ). Moreover, the exceptional safety score (90.6% in MedSE) of the much smaller Baichuan-M2-32B highlights that targeted training is equally critical. Our specialized judge model, trained via SFT on a 19k expert-annotated medical dataset, achieves 92.1% accuracy, an F1-score of 94.37%, and a Cohen's Kappa of 81.3% for human-AI consistency, validating a reproducible and expert-aligned evaluation protocol. MLB thus provides a rigorous framework to guide the development of clinically viable LLMs.

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored, particularly in evaluating the quality of their reasoning processes alongside final outputs. Here, we introduce MedR-Bench, a benchmarking dataset of 1,453 structured patient cases, annotated with reasoning references derived from clinical case reports. Spanning 13 body systems and 10 specialties, it includes both common and rare diseases. To comprehensively evaluate LLM performance, we propose a framework encompassing three critical examination recommendation, diagnostic decision-making, and treatment planning, simulating the entire patient care journey. To assess reasoning quality, we present the Reasoning Evaluator, a novel automated system that objectively scores free-text reasoning responses based on efficiency, actuality, and completeness using dynamic cross-referencing and evidence checks. Using this benchmark, we evaluate five state-of-the-art reasoning LLMs, including DeepSeek-R1, OpenAI-o3-mini, and Gemini-2.0-Flash Thinking, etc. Our results show that current LLMs achieve over 85% accuracy in relatively simple diagnostic tasks when provided with sufficient examination results. However, performance declines in more complex tasks, such as examination recommendation and treatment planning. While reasoning outputs are generally reliable, with factuality scores exceeding 90%, critical reasoning steps are frequently missed. These findings underscore both the progress and limitations of clinical LLMs. Notably, open-source models like DeepSeek-R1 are narrowing the gap with proprietary systems, highlighting their potential to drive accessible and equitable advancements in healthcare.

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown some promise in the medical domain, their application in clinical diagnosis remains underexplored, especially in real-world clinical practice, where highly sophisticated, patient-specific decisions need to be made. Current evaluations of LLMs in this field are often narrow in scope, focusing on specific diseases or specialties and employing simplified diagnostic tasks. To bridge this gap, we introduce CliBench, a novel benchmark developed from the MIMIC IV dataset, offering a comprehensive and realistic assessment of LLMs' capabilities in clinical diagnosis. This benchmark not only covers diagnoses from a diverse range of medical cases across various specialties but also incorporates tasks of clinical significance: treatment procedure identification, lab test ordering and medication prescriptions. Supported by structured output ontologies, CliBench enables a precise and multi-granular evaluation, offering an in-depth understanding of LLM's capability on diverse clinical tasks of desired granularity. We conduct a zero-shot evaluation of leading LLMs to assess their proficiency in clinical decision-making. Our preliminary results shed light on the potential and limitations of current LLMs in clinical settings, providing valuable insights for future advancements in LLM-powered healthcare.

Existing medical VQA benchmarks mostly focus on single-image analysis, yet clinicians almost always compare a series of images before reaching a diagnosis. To better approximate this workflow, we introduce MedFrameQA -- the first benchmark that explicitly evaluates multi-image reasoning in medical VQA. To build MedFrameQA both at scale and in high-quality, we develop 1) an automated pipeline that extracts temporally coherent frames from medical videos and constructs VQA items whose content evolves logically across images, and 2) a multiple-stage filtering strategy, including model-based and manual review, to preserve data clarity, difficulty, and medical relevance. The resulting dataset comprises 2,851 VQA pairs (gathered from 9,237 high-quality frames in 3,420 videos), covering nine human body systems and 43 organs; every question is accompanied by two to five images. We comprehensively benchmark ten advanced Multimodal LLMs -- both proprietary and open source, with and without explicit reasoning modules -- on MedFrameQA. The evaluation challengingly reveals that all models perform poorly, with most accuracies below 50%, and accuracy fluctuates as the number of images per question increases. Error analysis further shows that models frequently ignore salient findings, mis-aggregate evidence across images, and propagate early mistakes through their reasoning chains; results also vary substantially across body systems, organs, and modalities. We hope this work can catalyze research on clinically grounded, multi-image reasoning and accelerate progress toward more capable diagnostic AI systems.

The availability of large public datasets and the increased amount of computing power have shifted the interest of the medical community to high-performance algorithms. However, little attention is paid to the quality of the data and their annotations. High performance on benchmark datasets may be reported without considering possible shortcuts or artifacts in the data, besides, models are not tested on subpopulation groups. With this work, we aim to raise awareness about shortcuts problems. We validate previous findings, and present a case study on chest X-rays using two publicly available datasets. We share annotations for a subset of pneumothorax images with drains. We conclude with general recommendations for medical image classification.

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to capture the unstructured, ambiguous, and long-tail complexities inherent in genuine user inquiries. To bridge this gap, we introduce QuarkMedBench, an ecologically valid benchmark tailored for real-world medical LLM assessment. We compiled a massive dataset spanning Clinical Care, Wellness Health, and Professional Inquiry, comprising 20,821 single-turn queries and 3,853 multi-turn sessions. To objectively evaluate open-ended answers, we propose an automated scoring framework that integrates multi-model consensus with evidence-based retrieval to dynamically generate 220,617 fine-grained scoring rubrics (~9.8 per query). During evaluation, hierarchical weighting and safety constraints structurally quantify medical accuracy, key-point coverage, and risk interception, effectively mitigating the high costs and subjectivity of human grading. Experimental results demonstrate that the generated rubrics achieve a 91.8% concordance rate with clinical expert blind audits, establishing highly dependable medical reliability. Crucially, baseline evaluations on this benchmark reveal significant performance disparities among state-of-the-art models when navigating real-world clinical nuances, highlighting the limitations of conventional exam-based metrics. Ultimately, QuarkMedBench establishes a rigorous, reproducible yardstick for measuring LLM performance on complex health issues, while its framework inherently supports dynamic knowledge updates to prevent benchmark obsolescence.

Time-series diagnostic reasoning is essential for many applications, yet existing solutions face a persistent gap: general reasoning large language models (GRLMs) possess strong reasoning skills but lack the domain-specific knowledge to understand complex time-series patterns. Conversely, fine-tuned time-series LLMs (TSLMs) understand these patterns but lack the capacity to generalize reasoning for more complicated questions. To bridge this gap, we propose a hybrid knowledge-injection framework that injects TSLM-generated insights directly into GRLM's reasoning trace, thereby achieving strong time-series reasoning with in-domain knowledge. As collecting data for knowledge injection fine-tuning is costly, we further leverage a reinforcement learning-based approach with verifiable rewards (RLVR) to elicit knowledge-rich traces without human supervision, then transfer such an in-domain thinking trace into GRLM for efficient knowledge injection. We further release SenTSR-Bench, a multivariate time-series-based diagnostic reasoning benchmark collected from real-world industrial operations. Across SenTSR-Bench and other public datasets, our method consistently surpasses TSLMs by 9.1%-26.1% and GRLMs by 7.9%-22.4%, delivering robust, context-aware time-series diagnostic insights.

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative medical evidence to support diagnostic hypotheses. Such evidence typically aligns with an inferred diagnosis rather than the surface form of a patient's symptoms, leading to low lexical or semantic overlap between queries and relevant documents. To address this gap, we introduce R2MED, the first benchmark explicitly designed for reasoning-driven medical retrieval. It comprises 876 queries spanning three tasks: Q&A reference retrieval, clinical evidence retrieval, and clinical case retrieval. These tasks are drawn from five representative medical scenarios and twelve body systems, capturing the complexity and diversity of real-world medical information needs. We evaluate 15 widely-used retrieval systems on R2MED and find that even the best model achieves only 31.4 nDCG@10, demonstrating the benchmark's difficulty. Classical re-ranking and generation-augmented retrieval methods offer only modest improvements. Although large reasoning models improve performance via intermediate inference generation, the best results still peak at 41.4 nDCG@10. These findings underscore a substantial gap between current retrieval techniques and the reasoning demands of real clinical tasks. We release R2MED as a challenging benchmark to foster the development of next-generation medical retrieval systems with enhanced reasoning capabilities. Data and code are available at https://github.com/R2MED/R2MED

Artificial intelligence (AI) can automatically delineate lesions on computed tomography (CT) and generate radiology report content, yet progress is limited by the scarcity of publicly available CT datasets with lesion-level annotations. To bridge this gap, we introduce CT-Bench, a first-of-its-kind benchmark dataset comprising two components: a Lesion Image and Metadata Set containing 20,335 lesions from 7,795 CT studies with bounding boxes, descriptions, and size information, and a multitask visual question answering benchmark with 2,850 QA pairs covering lesion localization, description, size estimation, and attribute categorization. Hard negative examples are included to reflect real-world diagnostic challenges. We evaluate multiple state-of-the-art multimodal models, including vision-language and medical CLIP variants, by comparing their performance to radiologist assessments, demonstrating the value of CT-Bench as a comprehensive benchmark for lesion analysis. Moreover, fine-tuning models on the Lesion Image and Metadata Set yields significant performance gains across both components, underscoring the clinical utility of CT-Bench.

We present DM-Bench, the first benchmark designed to evaluate large language model (LLM) performance across real-world decision-making tasks faced by individuals managing diabetes in their daily lives. Unlike prior health benchmarks that are either generic, clinician-facing or focused on clinical tasks (e.g., diagnosis, triage), DM-Bench introduces a comprehensive evaluation framework tailored to the unique challenges of prototyping patient-facing AI solutions in diabetes, glucose management, metabolic health and related domains. Our benchmark encompasses 7 distinct task categories, reflecting the breadth of real-world questions individuals with diabetes ask, including basic glucose interpretation, educational queries, behavioral associations, advanced decision making and long term planning. Towards this end, we compile a rich dataset comprising one month of time-series data encompassing glucose traces and metrics from continuous glucose monitors (CGMs) and behavioral logs (e.g., eating and activity patterns) from 15,000 individuals across three different diabetes populations (type 1, type 2, pre-diabetes/general health and wellness). Using this data, we generate a total of 360,600 personalized, contextual questions across the 7 tasks. We evaluate model performance on these tasks across 5 metrics: accuracy, groundedness, safety, clarity and actionability. Our analysis of 8 recent LLMs reveals substantial variability across tasks and metrics; no single model consistently outperforms others across all dimensions. By establishing this benchmark, we aim to advance the reliability, safety, effectiveness and practical utility of AI solutions in diabetes care.

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and specialized assessments. However, these benchmarks have limitations in question design (mostly multiple-choice), data sources (often not derived from real clinical scenarios), and evaluation methods (poor assessment of complex reasoning). To address these issues, we present LLMEval-Med, a new benchmark covering five core medical areas, including 2,996 questions created from real-world electronic health records and expert-designed clinical scenarios. We also design an automated evaluation pipeline, incorporating expert-developed checklists into our LLM-as-Judge framework. Furthermore, our methodology validates machine scoring through human-machine agreement analysis, dynamically refining checklists and prompts based on expert feedback to ensure reliability. We evaluate 13 LLMs across three categories (specialized medical models, open-source models, and closed-source models) on LLMEval-Med, providing valuable insights for the safe and effective deployment of LLMs in medical domains. The dataset is released in https://github.com/llmeval/LLMEval-Med.

Existing medical reasoning benchmarks for vision-language models primarily focus on analyzing a patient's condition based on an image from a single visit. However, this setting deviates significantly from real-world clinical practice, where doctors typically refer to a patient's historical conditions to provide a comprehensive assessment by tracking their changes over time. In this paper, we introduce TemMed-Bench, the first benchmark designed for analyzing changes in patients' conditions between different clinical visits, which challenges large vision-language models (LVLMs) to reason over temporal medical images. TemMed-Bench consists of a test set comprising three tasks - visual question-answering (VQA), report generation, and image-pair selection - and a supplementary knowledge corpus of over 17,000 instances. With TemMed-Bench, we conduct an evaluation of six proprietary and six open-source LVLMs. Our results show that most LVLMs lack the ability to analyze patients' condition changes over temporal medical images, and a large proportion perform only at a random-guessing level in the closed-book setting. In contrast, GPT o3, o4-mini and Claude 3.5 Sonnet demonstrate comparatively decent performance, though they have yet to reach the desired level. Furthermore, we explore augmenting the input with both retrieved visual and textual modalities in the medical domain. We also show that multi-modal retrieval augmentation yields notably higher performance gains than no retrieval and textual retrieval alone across most models on our benchmark, with the VQA task showing an average improvement of 2.59%. Overall, we compose a benchmark grounded on real-world clinical practice, and it reveals LVLMs' limitations in temporal medical image reasoning, as well as highlighting the use of multi-modal retrieval augmentation as a potentially promising direction worth exploring to address this challenge.

Benchmark quality is critical for meaningful evaluation and sustained progress in time series forecasting, particularly given the recent rise of pretrained models. Existing benchmarks often have narrow domain coverage or overlook important real-world settings, such as tasks with covariates. Additionally, their aggregation procedures often lack statistical rigor, making it unclear whether observed performance differences reflect true improvements or random variation. Many benchmarks also fail to provide infrastructure for consistent evaluation or are too rigid to integrate into existing pipelines. To address these gaps, we propose fev-bench, a benchmark comprising 100 forecasting tasks across seven domains, including 46 tasks with covariates. Supporting the benchmark, we introduce fev, a lightweight Python library for benchmarking forecasting models that emphasizes reproducibility and seamless integration with existing workflows. Usingfev, fev-bench employs principled aggregation methods with bootstrapped confidence intervals to report model performance along two complementary dimensions: win rates and skill scores. We report results on fev-bench for various pretrained, statistical and baseline models, and identify promising directions for future research.

AI-driven models have demonstrated significant potential in automating radiology report generation for chest X-rays. However, there is no standardized benchmark for objectively evaluating their performance. To address this, we present ReXrank, https://rexrank.ai, a public leaderboard and challenge for assessing AI-powered radiology report generation. Our framework incorporates ReXGradient, the largest test dataset consisting of 10,000 studies, and three public datasets (MIMIC-CXR, IU-Xray, CheXpert Plus) for report generation assessment. ReXrank employs 8 evaluation metrics and separately assesses models capable of generating only findings sections and those providing both findings and impressions sections. By providing this standardized evaluation framework, ReXrank enables meaningful comparisons of model performance and offers crucial insights into their robustness across diverse clinical settings. Beyond its current focus on chest X-rays, ReXrank's framework sets the stage for comprehensive evaluation of automated reporting across the full spectrum of medical imaging.

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination, where test sets inadvertently leak into training corpora, leading to inflated performance estimates; and (2) temporal misalignment, failing to capture the rapid evolution of medical knowledge. Furthermore, current evaluation metrics for open-ended clinical reasoning often rely on either shallow lexical overlap (e.g., ROUGE) or subjective LLM-as-a-Judge scoring, both inadequate for verifying clinical correctness. To bridge these gaps, we introduce LiveMedBench, a continuously updated, contamination-free, and rubric-based benchmark that weekly harvests real-world clinical cases from online medical communities, ensuring strict temporal separation from model training data. We propose a Multi-Agent Clinical Curation Framework that filters raw data noise and validates clinical integrity against evidence-based medical principles. For evaluation, we develop an Automated Rubric-based Evaluation Framework that decomposes physician responses into granular, case-specific criteria, achieving substantially stronger alignment with expert physicians than LLM-as-a-Judge. To date, LiveMedBench comprises 2,756 real-world cases spanning 38 medical specialties and multiple languages, paired with 16,702 unique evaluation criteria. Extensive evaluation of 38 LLMs reveals that even the best-performing model achieves only 39.2%, and 84% of models exhibit performance degradation on post-cutoff cases, confirming pervasive data contamination risks. Error analysis further identifies contextual application-not factual knowledge-as the dominant bottleneck, with 35-48% of failures stemming from the inability to tailor medical knowledge to patient-specific constraints.

Multimodal large language models (MLLMs) have made significant strides, yet they face challenges in the medical domain due to limited specialized knowledge. While recent medical MLLMs demonstrate strong performance in lab settings, they often struggle in real-world applications, highlighting a substantial gap between research and practice. In this paper, we seek to address this gap at various stages of the end-to-end learning pipeline, including data collection, model fine-tuning, and evaluation. At the data collection stage, we introduce SemiHVision, a dataset that combines human annotations with automated augmentation techniques to improve both medical knowledge representation and diagnostic reasoning. For model fine-tuning, we trained PMC-Cambrian-8B-AN over 2400 H100 GPU hours, resulting in performance that surpasses public medical models like HuatuoGPT-Vision-34B (79.0% vs. 66.7%) and private general models like Claude3-Opus (55.7%) on traditional benchmarks such as SLAKE and VQA-RAD. In the evaluation phase, we observed that traditional benchmarks cannot accurately reflect realistic clinical task capabilities. To overcome this limitation and provide more targeted guidance for model evaluation, we introduce the JAMA Clinical Challenge, a novel benchmark specifically designed to evaluate diagnostic reasoning. On this benchmark, PMC-Cambrian-AN achieves state-of-the-art performance with a GPT-4 score of 1.29, significantly outperforming HuatuoGPT-Vision-34B (1.13) and Claude3-Opus (1.17), demonstrating its superior diagnostic reasoning abilities.