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- ---
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- license: mit
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ license: mit
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+ language:
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+ - en
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+ library_name: jax
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+ tags:
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+ - perturbation-prediction
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+ - prior-data-fitted-networks
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+ - in-context-learning
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+ - single-cell
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+ - causal-inference
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+ - diffusion-transformer
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+ datasets:
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+ - marvinsxtr/MapPFN
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+ pipeline_tag: other
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+ ---
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+
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+ # MapPFN Weights
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+
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+ Pre-trained and fine-tuned checkpoints for [MapPFN: Learning Causal Perturbation Maps in Context](https://arxiv.org/abs/2601.21092) (Sextro et al., 2026).
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+
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+ ## Checkpoints
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+
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+ - `model.ckpt` — Pre-trained on synthetic biological prior (50 dimensions, 400k steps)
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+ - `model_finetuned_frangieh.ckpt` — Fine-tuned on [Frangieh et al. (2021)](https://doi.org/10.1038/s41588-021-00779-1)
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+ - `model_finetuned_papalexi.ckpt` — Fine-tuned on [Papalexi et al. (2021)](https://doi.org/10.1038/s41588-021-00778-2)
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+
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+ All checkpoints share the same MMDiT architecture (~25M parameters) and differ only in training data. See the [GitHub repository](https://github.com/marvinsxtr/MapPFN) for inference and fine-tuning code.
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+
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+ ## Citation
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+
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+ ```bibtex
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+ @article{sextro2026mappfn,
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+ title = {{MapPFN}: Learning Causal Perturbation Maps in Context},
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+ author = {Sextro, Marvin and K\l{}os, Weronika and Dernbach, Gabriel},
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+ journal = {arXiv preprint arXiv:2601.21092},
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+ year = {2026}
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+ }
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+ ```
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+
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+ **Links:** [Paper](https://arxiv.org/abs/2601.21092) | [Code](https://github.com/marvinsxtr/MapPFN) | [Datasets](https://huggingface.co/datasets/marvinsxtr/MapPFN) | [Project Page](https://marvinsxtr.github.io/MapPFN)