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siddharthtumre
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Revised-JNLPBA

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1901
[ "It", "seems", "therefore", "that", "PGE2", ",", "by", "elevating", "cAMP", "levels", ",", "interferes", "with", "the", "activation", "pathway", "for", "NF-kappa", "B", "but", "not", "for", "NF-AT", ",", "AP-1", "or", "CLE0", "binding", "protein", "." ]
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1902
[ "Characterization", "of", "NF", "(", "P", ")", ",", "the", "nuclear", "factor", "that", "interacts", "with", "the", "regulatory", "P", "sequence", "(", "5'-CGAAAATTTCC-3", "'", ")", "of", "the", "human", "interleukin-4", "gene", ":", "relationship", "to", "N...
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1903
[ "The", "P", "sequence", "of", "the", "human", "interleukin-4", "(", "IL-4", ")", "gene", ",", "which", "was", "defined", "as", "a", "responsive", "element", "for", "phorbol", "12-myristate", "13-acetate", "and", "calcium", "ionophore", "(", "A23187", ")", "i...
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1904
[ "We", "examined", "whether", "NF", "(", "P", ")", ",", "a", "nuclear", "factor", "specific", "for", "the", "P", "sequence", ",", "is", "related", "to", "NF-kappa", "B", "and", "NF-AT", "." ]
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1905
[ "NF-kappa", "B", "(", "P65", "or", "P65/P50", "heterodimer", ")", "bound", "to", "the", "P", "sequence", "in", "electrophoretic", "mobility", "shift", "assays", "(", "EMSA", ")", "and", "activated", "transcription", "through", "the", "P", "sequence", "when", ...
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1906
[ "In", "EMSAs", ",", "NF", "(", "P", ")", "binding", "was", "inhibited", "by", "the", "unlabeled", "NF-AT", "binding", "site", "but", "not", "by", "the", "unlabeled", "AP1", "binding", "site", "and", "purified", "NF-AT", "contained", "an", "activity", "that...
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1907
[ "Both", "mobility", "shift", "and", "sequence", "specificity", "of", "NF-AT", "were", "similar", "to", "those", "of", "NF", "(", "P", ")", "and", "only", "a", "small", "amount", "of", "P65", "was", "detected", "in", "NF", "(", "P", ")", "in", "crude", ...
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1908
[ "These", "results", "indicate", "that", "the", "component", "(", "s", ")", "of", "NF-AT", "has", "the", "potential", "to", "reconstitute", "NF", "(", "P", ")", "whereas", "NF-kappa", "B", "alone", "can", "not", "account", "for", "NF", "(", "P", ")", "i...
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1909
[ "Unlike", "NF-AT", ",", "NF", "(", "P", ")", "does", "not", "contain", "AP1", "as", "its", "DNA", "binding", "component", "." ]
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1910
[ "Activation", "of", "early", "growth", "response", "1", "gene", "transcription", "and", "pp90rsk", "during", "induction", "of", "monocytic", "differentiation", "." ]
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1911
[ "The", "present", "work", "has", "studied", "mechanisms", "responsible", "for", "induction", "of", "early", "growth", "response", "1", "(", "EGR-1", ")", "gene", "expression", "during", "monocytic", "differentiation", "of", "U-937", "myeloid", "leukemia", "cells",...
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1912
[ "Differentiation", "of", "U-937", "cells", "with", "12-O-tetradecanoylphorbol-13-acetate", "(", "TPA", ")", ",", "an", "activator", "of", "the", "serine/threonine", "protein", "kinase", "C", ",", "was", "associated", "with", "transcriptional", "activation", "of", "E...
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1913
[ "The", "EGR-1", "promoter", "contains", "six", "CC", "(", "A/T", ")", "6GG", "(", "CArG", ")", "motifs", "." ]
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1914
[ "The", "two", "5'-most", "distal", "CArG", "sequences", "conferred", "TPA", "inducibility", "." ]
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1915
[ "In", "contrast", ",", "there", "was", "little", "effect", "of", "TPA", "on", "EGR-1", "transcription", "in", "a", "TPA-resistant", "U-937", "cell", "variant", ",", "designated", "TUR", "." ]
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1916
[ "Treatment", "of", "both", "U-937", "and", "TUR", "cells", "with", "okadaic", "acid", ",", "an", "inhibitor", "of", "serine/threonine", "protein", "phosphatases", "1", "and", "2A", ",", "was", "associated", "with", "induction", "of", "monocytic", "differentiatio...
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1917
[ "Since", "these", "findings", "supported", "the", "involvement", "of", "serine/threonine", "protein", "phosphorylation", "in", "the", "regulation", "of", "EGR-1", "expression", ",", "we", "studied", "activation", "of", "the", "40S", "ribosomal", "protein", "S6", "...
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1918
[ "Although", "both", "kinases", "participate", "in", "regulating", "cell", "growth", ",", "there", "was", "no", "detectable", "activation", "of", "pp70S6K", "during", "TPA-", "or", "okadaic", "acid-induced", "monocytic", "differentiation", "." ]
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1919
[ "Moreover", ",", "rapamycin", ",", "an", "inhibitor", "of", "pp70S6K", "activation", ",", "had", "no", "effect", "on", "induction", "of", "EGR-1", "expression", "." ]
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1920
[ "In", "contrast", ",", "analysis", "of", "pp90rsk", "activity", "by", "phosphorylation", "of", "a", "peptide", "derived", "from", "S6", "protein", "demonstrated", "stimulation", "of", "this", "kinase", "in", "TPA-treated", "U-937", ",", "and", "not", "TUR", ",...
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1921
[ "Okadaic", "acid", "treatment", "of", "both", "cell", "types", "was", "associated", "with", "activation", "of", "pp90rsk", "." ]
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1922
[ "Antioxidants", "inhibit", "monocyte", "adhesion", "by", "suppressing", "nuclear", "factor-kappa", "B", "mobilization", "and", "induction", "of", "vascular", "cell", "adhesion", "molecule-1", "in", "endothelial", "cells", "stimulated", "to", "generate", "radicals", "....
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1923
[ "Cell", "adhesion", "to", "endothelial", "cells", "stimulated", "by", "tumor", "necrosis", "factor-alpha", "(", "TNF", ")", "is", "due", "to", "induction", "of", "surface", "receptors", ",", "such", "as", "vascular", "cell", "adhesion", "molecule-1", "(", "VCA...
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1924
[ "The", "antioxidant", "pyrrolidine", "dithiocarbamate", "(", "PDTC", ")", "specifically", "inhibits", "activation", "of", "nuclear", "factor-kappa", "B", "(", "NF-kappa", "B", ")", "." ]
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1925
[ "Since", "kappa", "B", "motifs", "are", "present", "in", "VCAM-1", "and", "intercellular", "adhesion", "molecule-1", "(", "ICAM-1", ")", "promoters", ",", "we", "used", "PDTC", "to", "study", "the", "regulatory", "mechanisms", "of", "VCAM-1", "and", "ICAM-1", ...
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1926
[ "PDTC", "or", "N-acetylcysteine", "dose", "dependently", "reduced", "TNF-induced", "VCAM-1", "but", "not", "ICAM-1", "surface", "protein", "(", "also", "in", "human", "umbilical", "arterial", "endothelial", "cells", ")", "and", "mRNA", "expression", "(", "by", "...
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1927
[ "Gel-shift", "analysis", "in", "HUVECs", "demonstrated", "that", "PDTC", "prevented", "NF-kappa", "B", "mobilization", "by", "TNF", ",", "suggesting", "that", "only", "VCAM-1", "induction", "was", "controlled", "by", "NF-kappa", "B", "." ]
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1928
[ "Since", "HUVECs", "released", "superoxide", "anions", "in", "response", "to", "TNF", ",", "and", "H2O2", "induces", "VCAM-1", ",", "PDTC", "may", "act", "as", "a", "radical", "scavenger", "." ]
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1929
[ "Although", "ICAM-1", "induction", "was", "unaffected", ",", "inhibitors", "of", "NADPH", "oxidase", "(", "apocynin", ")", "or", "cytochrome", "P-450", "(", "SKF525a", ")", "suppressed", "VCAM-1", "induction", "by", "TNF", ",", "revealing", "that", "several", ...
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1930
[ "PDTC", ",", "apocynin", ",", "or", "SKF525a", "decreased", "adhesion", "of", "monocytic", "U937", "cells", "to", "TNF-treated", "HUVECs", "(", "by", "75", "%", "at", "100", "mumol/L", "PDTC", ")", "." ]
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1931
[ "Inhibition", "by", "anti-VCAM-1", "monoclonal", "antibody", "1G11", "indicated", "that", "U937", "adhesion", "was", "VCAM-1", "dependent", "and", "suppression", "by", "antioxidants", "was", "due", "to", "reduced", "VCAM-1", "induction", "." ]
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1932
[ "(", "ABSTRACT", "TRUNCATED", "AT", "250", "WORDS", ")" ]
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1933
[ "Displacement", "of", "an", "E-box-binding", "repressor", "by", "basic", "helix-loop-helix", "proteins", ":", "implications", "for", "B-cell", "specificity", "of", "the", "immunoglobulin", "heavy-chain", "enhancer", "." ]
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1934
[ "The", "activity", "of", "the", "immunoglobulin", "heavy-chain", "(", "IgH", ")", "enhancer", "is", "restricted", "to", "B", "cells", ",", "although", "it", "binds", "both", "B-cell-restricted", "and", "ubiquitous", "transcription", "factors", "." ]
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1935
[ "Activation", "of", "the", "enhancer", "in", "non-B", "cells", "upon", "overexpression", "of", "the", "basic", "helix-loop-helix", "(", "bHLH", ")", "protein", "E2A", "appears", "to", "be", "mediated", "not", "only", "by", "the", "binding", "of", "E2A", "to"...
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1936
[ "We", "have", "identified", "a", "``", "two-handed", "''", "zinc", "finger", "protein", ",", "denoted", "ZEB", ",", "the", "DNA-binding", "specificity", "of", "which", "mimics", "that", "of", "the", "cellular", "repressor", "." ]
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1937
[ "By", "employing", "a", "derivative", "E", "box", "that", "binds", "ZEB", "but", "not", "E2A", ",", "we", "have", "shown", "that", "the", "repressor", "is", "active", "in", "B", "cells", "and", "the", "IgH", "enhancer", "is", "silenced", "in", "the", "...
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1938
[ "Hence", ",", "we", "propose", "that", "a", "necessary", "prerequisite", "of", "enhancer", "activity", "is", "the", "B-cell-specific", "displacement", "of", "a", "ZEB-like", "repressor", "by", "bHLH", "proteins", "." ]
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1939
[ "Inhibition", "of", "NF-kappa", "B", "by", "sodium", "salicylate", "and", "aspirin", "[", "see", "comments", "]" ]
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1940
[ "The", "transcription", "factor", "nuclear", "factor-kappa", "B", "(", "NF-kappa", "B", ")", "is", "critical", "for", "the", "inducible", "expression", "of", "multiple", "cellular", "and", "viral", "genes", "involved", "in", "inflammation", "and", "infection", "...
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1941
[ "The", "anti-inflammatory", "drugs", "sodium", "salicylate", "and", "aspirin", "inhibited", "the", "activation", "of", "NF-kappa", "B", ",", "which", "further", "explains", "the", "mechanism", "of", "action", "of", "these", "drugs", "." ]
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1942
[ "This", "inhibition", "prevented", "the", "degradation", "of", "the", "NF-kappa", "B", "inhibitor", ",", "I", "kappa", "B", ",", "and", "therefore", "NF-kappa", "B", "was", "retained", "in", "the", "cytosol", "." ]
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1943
[ "Sodium", "salicylate", "and", "aspirin", "also", "inhibited", "NF-kappa", "B", "-dependent", "transcription", "from", "the", "Ig", "kappa", "enhancer", "and", "the", "human", "immunodeficiency", "virus", "(", "HIV", ")", "long", "terminal", "repeat", "(", "LTR"...
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1944
[ "Effects", "of", "the", "antisense", "myb", "expression", "on", "hemin-", "and", "erythropoietin-", "induced", "erythroid", "differentiation", "of", "K562", "cells", "." ]
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1945
[ "In", "order", "to", "elucidate", "the", "role", "of", "c-myb", "gene", "in", "erythroid", "differentiation", "of", "K562", "cell", "induced", "by", "hemin", "(", "Hm", ")", "and", "erythropoietin", "(", "Epo", ")", ",", "we", "constructed", "recombinant", ...
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1946
[ "During", "treatment", "with", "Hm", ",", "K562", "cells", "constitutively", "expressed", "c-myb", "mRNA", ",", "and", "50", "%", "of", "them", "began", "to", "synthesize", "hemoglobin", "(", "Hb", ")", "." ]
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1947
[ "Expression", "of", "antisense", "myb", "RNA", "reduced", "the", "amount", "of", "c-myb", "mRNA", ",", "and", "the", "percentage", "of", "Hb-synthesizing", "cells", "was", "decreased", "to", "20", "%", "." ]
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1948
[ "In", "the", "presence", "of", "Epo", ",", "c-myb", "mRNA", "declined", "and", "20", "%", "of", "K562", "cells", "synthesized", "Hb", "regardless", "of", "antisense", "myb", "RNA", "expression", "." ]
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1949
[ "It", "is", "suggested", "that", "constitutive", "expression", "of", "c-myb", "mRNA", "is", "necessary", "for", "Hm", "-induced", "differentiation", ",", "and", "that", "a", "decrease", "in", "the", "amount", "of", "c-myb", "mRNA", "induced", "by", "antisense"...
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1950
[ "The", "amount", "of", "c-myb", "mRNA", "in", "K562", "cells", "was", "reduced", "during", "the", "differentiation", "induced", "by", "Epo", "." ]
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1951
[ "Expression", "of", "GATA-1", "mRNA", "was", "almost", "constant", "during", "Hm", "-induced", "differentiation", ",", "but", "increased", "during", "Epo", "treatment", "." ]
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1952
[ "It", "is", "supposed", "that", "the", "mechanism", "of", "Hm", "-induced", "differentiation", "is", "distinguished", "from", "that", "of", "Epo", "-induced", "differentiation", "in", "K562", "cells", "." ]
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1953
[ "Prenatal", "immune", "challenge", "alters", "the", "hypothalamic-pituitary-adrenocortical", "axis", "in", "adult", "rats", "." ]
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1954
[ "We", "investigated", "whether", "non-abortive", "maternal", "infections", "would", "compromise", "fetal", "brain", "development", "and", "alter", "hypothalamic-pituitary-adrenocortical", "(", "HPA", ")", "axis", "functioning", "when", "adult", "." ]
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1955
[ "To", "study", "putative", "teratogenic", "effects", "of", "a", "T", "cell-mediated", "immune", "response", "versus", "an", "endotoxic", "challenge", ",", "10-d-pregnant", "rats", "received", "a", "single", "intraperitoneal", "injection", "of", "5", "x", "10", "...
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1956
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1957
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1958
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1959
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1960
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1961
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1962
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1963
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1964
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1965
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1966
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1967
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1968
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1969
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1970
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1971
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1972
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1973
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1974
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1975
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1976
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1977
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1978
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1979
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1980
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1981
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1982
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1983
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1984
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1985
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1986
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1987
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1988
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1989
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1990
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1991
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1992
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1993
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1994
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1995
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1996
[ "The", "host", "response", "to", "Mycobacterium", "tuberculosis", "includes", "granuloma", "formation", "at", "sites", "of", "infection", "and", "systemic", "symptoms", "." ]
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1997
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1998
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1999
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2000
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