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135
ef3c0d08-da03-488e-967c-4f41251b303a
Features of Gegenhalten are all exept
It is voluntary opposition by patient to passive movement of limb
It is stiffening of limb in response to contact
Strength of antagonists remains the same as examiner uses increased force to change limb position
It is present throughout the range of motion
2c
multi
Answer- C. Strength of antagonists remains the same as examiner uses increased force to change limb positionIt is ako called paratonia or paratonic rigidity.It is the voluntary opposition of patient to passive movement of limb.It is the movement of the limb to counteract any movement made by the examiner.The resistance...
Medicine
null
7948a629-ef97-4627-b861-62bdd399f224
'Moron' is one with an IQ of
0-24
25-49
50-69
70-79
2c
single
Levels of intelligence IQ range Idiot 0 - 24 Imbecile 25 - 49 Moron 50 - 69 Borderline 70 - 79 Low normal 80 - 89 Normal 90 - 109 Superior 110 - 119 Very superior 120 - 139 Near genius 140 and over
Social & Preventive Medicine
Mental Health
144d4965-7ed3-470f-a28a-f121e01d082f
All of the following statements about Acute Attack in gouty ahritis are true, except:-
Joint aspirate reveals negative birefringent crystals
Allopurinol should be staed immediately
Colchicine is known to provide relief
Serum uric acid levels may be normal
1b
multi
Answer is B (Allopurinol should be staed immediately): Allopurinol should not be staed immediately in acute attack of gout as it may precipitate acute symptoms. The mainstay of treatment in acute gouty ahritis is the administration of anti inflammatory drugs such as NSAID, Cochicine and /or glucocoicoids. Allopurinol s...
Medicine
null
b9d4b790-c120-486e-b1b5-1730993c9012
Machine used noninvasively to monitor an external chest compression during cardiopulmonary resuscitation is ?
Zoll AED - plus automatic external defibrillator
Zoll depth synchronizer
Zoll strength sensor
Zoll pA02 monitor
0a
single
Ans. is 'a' i.e., Zoll automatic external defibrillator Monitor for chest compressions in cardio pulmonary resuscitation A novel monitor for the chest compressions is a device incorporated into the chest compression pad of the ZOLL AED - PLUS automatic external defeibrillator. The sternal compression pad located betwee...
Anaesthesia
null
96e57c1b-b2b7-4a4e-8566-8b7fe15f6893
Oxidative decarboxylation of pyruvate requires
NADP+
Cytochromes
pyridoxal phosphate
COASH
3d
single
Inside the mitochondria, pyruvate is oxidatively decarboxylated to acetyl CoA by pyruvate dehydrogenase (PDH). It is a multi-enzyme complex with 5 co-enzymes and 3 apo-enzymes. The co-enzymes needed are: Thiamine pyrophosphate (TPP) Co-enzyme A (CoA) FAD NAD+ Lipoamide. The enzyme part of the PDH complex is made up of...
Biochemistry
null
0885b0cc-fb46-4d74-8510-c89293c446ee
Rigor mois stas in :
Right iliac fossa
Left iliac fossa
Brain
Hea
3d
single
D i.e. Hea
Forensic Medicine
null
a1b56466-2a0b-4fa8-86f2-cf6e691990c5
Thyroid nodule of 4 cm size, mobile but causing compressive symptoms. All are true except:
FNAC is investigation of choice
FNAC cannot distinguish follicular adenoma from carcinoma
Managed by total thyroidectomy
Cold nodule are diagnostic of malignancy
3d
multi
Thyroid nodule investigation of choice is FNAC, but does not distinguish between Adenoma and Carcinoma. Managment is Total Thryoidectomy. Risk of malignancy for cold nodule is 17-20%
Surgery
Thyroid
db1aae26-8267-4bfc-bc95-c9f4a61cc1c9
In acute diveiculitis of the colon, the sigmoidoscopic finding is -
Mucosa is inflammed
Minute diveiculi seen
Saw toothed appearance
Sigmoidoscope cannot be passed beyond 15 cm
0a
single
Ans. is 'a' i.e., Mucosa is inflammed
Surgery
null
efbf69ff-d997-4a36-b325-5c2d2183a2f2
A 70 years old man with prostate cancer was given radiotherapy. The recurrence of the cancer is monitored biochemically by:
Androgens only
Prostate specific antigen and carcinoembryonic antigen
Prostate specific antigen only
ALP and CEA
2c
multi
Ans. c. Prostate specific antigen only
Surgery
null
a046c29b-7c6e-4080-bbe6-489795b4482f
True about molluscum contagiosum is all except
Dome shape umbilicated papules.
Contagious until the lesions resolve.
Most lesions regress spontaneously by 6 → 12 months.
With Giemsa staining, molluscum bodies are seen intranuclearly.
3d
multi
Molluscum bodies are intracytoplasmic inclusion bodies.
Gynaecology & Obstetrics
null
46347c82-002b-463c-a432-b5d3c011189e
True about Anion Gap:
It is difference between unmeasured anions and unmeasured cations
Normal value is 20 mEq/L
In Diarrhoea anion gap is increased
Anion gap will increase if increases
0a
multi
The cation normally measured is Na+, and the anions are usually Cl- and HCO3-. The "anion gap" is the difference between unmeasured anions and unmeasured cations and is estimated as Normal range: 8-16 mEq/L Increase in chloride ion will decrease anion gap Increased Anion Gap (Normochloremia) Normal Anion Gap (Hyperchlo...
Physiology
Excretory System (Kidney, Bladder) Acid-Base Balance
4db1db78-546f-4ff4-8d70-6a6b89145651
Acute hyponatremia in 8 month old infant may produce all except-
Diarrhoea
Convulsions
Muscle cramps and weakness
Vascular collapse
0a
multi
Ans. is 'a' i.e., Diarrhoea Hyponatremia o Hyponatremia is defined as serum concentrationof Na+ < 130 meq/L. o Hyponatremia causes a decrease in the osmolality of ECF. Because the intracellular space then has a higher osmolality, water Inevitably moves from the extracellular to intracellular space. o Increase in intrac...
Pediatrics
null
a009a3a1-47df-4cf0-89eb-255f28c48c28
Transitional cell carcinoma of bladder is associated with -
Schistosomiasis
Naphthylamine
Smoking
All
3d
multi
Ans 'a' Schistosomiasis; 'b' Naphthylamine ; 'c' Smoking Risk factors for Transitional cell ca of Bladder 1) Cigarette smoking - is the main etiological factor and accounts for about 50% of bladder cancers. 2) Occupational exposures to chemicals the following compounds may be carcinogenic - 2 naphthylamine - combustion...
Surgery
null
658578c9-c745-47ac-b226-f9b4a9e950fd
Hormonal contraceptive of choice in a lactating woman is -
Combined pill
Multiphastic pill
Mini-pill
Centchroman
2c
single
Ans. is 'c' i.e., Mini-pill
Social & Preventive Medicine
null
e605a6e8-1b2c-4510-aa28-29e0e827748f
Where in the kidney does acitve reabsorption of sodium ions occur -
Collecting duct
Distal tubule
Ascending limb of Henle
All of the above
3d
multi
D i.e. All
Physiology
null
9d1458c0-749a-4d12-94ac-15671473f14a
In Crohn's disease all are seen except :a) Hyperplastic polypsb) Diverticulosisc) Fissuring ulcerd) Epitheloid granulomae) Crypt abscess
ac
ab
ad
bc
1b
multi
null
Surgery
null
94ab7ef0-349a-4525-9487-de2cb27b9c10
Cigarette smoking increases the risk of all the following diseases except
Pancreatic carcinoma
Cerebrovascular accident
Sudden infant death syndrome
Primary pulmonary hypeention
3d
multi
Answer- D. Primary pulmonary hypeention Coronayhea diseaseCerbrovascularlesionsAoic aneurysmChronic airway obstructionSudden infant death syndromeInfant respiratory distress syndromeCancer of Pancreas, Lung, Kidney.
Medicine
null
8e47093f-af63-4555-809c-17d5de98658b
Which of the following is a long acting insulin preparation?
Insulin lente
Isophane insulin
Insulin lispro
Insulin detemir
3d
single
Ans. is 'd' i.e., Insulin detemir * Insulin detemir and insulin glargine are the long acting insulin preparations.
Pharmacology
Endocrinology
8b6d30fb-a8b2-48b8-a2d0-e8ee6fec7eaf
All of the following act through GABA except ?
Phenobarbitone
Carbamazepene
Zopiclone
Muscimol
1b
multi
Ans. is 'b' i.e., Carbamazepene
Pharmacology
null
7ee8df76-e938-4a82-802e-9c35f4b73648
Which one of the following provides most conservative approach while restoring the tooth?
Cast gold
Dental amalgam
Glass ionomer cement
Composite resin
3d
single
null
Dental
null
0dcc34a8-218b-49ef-8847-28b1d27f492f
Annealing of gold foil is the process by which
Contaminants are removed from the surface
Rigidity decreases and ductility increases
Both ductility and proportional limit decreases
None of the above
0a
multi
Because gold attracts gases that render it noncohesive, such gases must be removed from the surface of the gold before dental compaction. This process is usually referred to as degassing or annealing and is accomplished by application of heat. Degassing is the preferred term, because the desired result is to remove res...
Dental
null
8bdfbcfd-f1c8-40b4-b7f8-fa5f4a41814a
Rapid depolarization (phase 0) of the action potential of ventricular muscle results from opening of:
Voltage-gated Ca2+ channels
Voltage-gated Na+ channels
Acetylcholine-activated K+ channels
Inward rectifying K+ channels
1b
single
Ans. B. Voltage-gated Na+ channelsVoltage-gated Na+ channels are responsible for phase 0 in ventricular muscle. Voltage gated Ca2+ channels are responsible for phase 0 in nodal cells. The potassium channels mentioned do not play a role in mediating depolarization.
Physiology
Heart, Circulation, and Blood
5dc95e11-a8e4-4869-ad75-2cee7436155a
Select the false statement about Pneumocystis jiroveci
It is seen only in immunocompromised individuals
Frequently associated with CMV
May be associated with pneumatoceles
Diagnosed with sputum microscopy
1b
multi
Pneumocystis jiroveci infection is transmitted by respiratory droplets and is asymptomatic in immunocompetent individuals. In immunocompromised individuals, life threatening pneumonia (pneumatocele) develops. Specimen - induced sputum, bronchoalveolar lavage or lung biopsy. Not associated with CMV. Ref: Textbook of Mic...
Microbiology
mycology
7fb7bf64-10a3-4b27-8792-2c4330b370d8
Cox pathway is not inhibited by
Aspirin
Indomethacin
Betamethasone
Diclofenac
2c
single
Aspirin inhibits Cox irreversibly by acetylating one of its serine residues;return of Cox activity depends are depends on synthesis of freshers I enzymes. other NSAIDs like indomethacin, diclofenac, etc are competative and Irreversible inhibitors of Cox, return of activity depends upon the dissociation from enzyme whic...
Anatomy
General anatomy
7e09b0ab-5e17-4374-a9ae-7e6289654335
Which defense mechanism is commonly used by substance abusers?
Dissociation
Introjection
Denial
Projection
2c
single
Ans. C. DenialDefense mechanism shown by drug addicts is denial.Defense mechanismDenialIs a psychotic type of defense mechanism where there is involuntary exclusion of unpleasant or painful reality from conscious awarenessRepressionSeemingly inexplicable naivete, memory lapse, or lack of awareness of physical status; t...
Psychiatry
Miscellaneous
ac58b89f-dbbc-4321-969f-f97c13320385
The following are the complications of trichobezoars except -
Haematemesis
Perforation and peritonitis
Obstruction
Malignancy
3d
multi
Rapunzel syndrome is the term for a trichobezoar (gastric 'hair ball') which has a tail-like extension into the small bowel through the pylorus causing gastric outlet obstruction.Human hair (especially long hair) is resistant to digestion as well as peristalsis. So it tends to stay in the stomach and over a period of t...
Surgery
Miscellaneous (Stomach & Duodenum)
febc10e6-0efc-4849-8853-39d6e3a458ba
Which of the following disorders is NOT aggravated by corticosteroid therapy ?
Congenital adrenal hyperplasia
Diabetes mellitus
Hypertension
Peptic ulcer
0a
single
null
Pharmacology
null
abb0f233-71d6-410f-8ed2-754df8183026
All of the following are peptide-based except
ACTH
GnRH
Thyroxin
TRH
2c
multi
Thyroxin is a lipid-soluble hormoneRef: DM Vasudevan, 7th edition, page no: 672
Biochemistry
Endocrinology
a5394a74-44f2-4996-9eb8-ad80a9bf4753
The voice is not affected in -
Unilateral abductor palsy
Unilateral adductor palsy
Partial abductor palsy
Total adductor palsy
0a
single
None of the given option is correct. Only paralysis in which voice is not affected is bilateral abductor paralysis. But in this question you can go ahead with unilateral abductor paralysis. Though the voice is affected in early stages of unilateral abductor paralysis, it gradually improves due to compensation by the he...
ENT
null
0e414374-efcd-496d-94d3-c52485ed5c59
cAMP mediates actions of all of the following hormones, EXCEPT:
Glucagon
Follicle stimulating hormone
Luteinizing hormone
Estrogen
3d
multi
Hormones acting by increasing cAMP levels are epinephrine and nor epinephrine binding to beta adrenergic receptors, vasopressin, prostaglandin E2, glucagon, LH, FSH, TSH, ACTH and PGE2. Signal transduction mechanisms in hormone action: Receptors that mediate tyrosine kinase activation: Insulin Growth factors (PDGF, EGF...
Pharmacology
null
6d69598c-ea18-4772-9dcf-72f438c32fed
Branches of brachial aery are all except ?
Profunda brachii
Superior ulnar collateral
Inferior ulnar collateral
Radial collateral
3d
multi
Ans. is 'd' i.e., Radial collateralo Radial collateral is a branch ofprofimda branchii aery, which in turn is a branch of brachial aery (Radial collateral aery is not a direct branch of brachial aery).Brachial aery o It begins as a continuation of axillary aery at level of lower border of teres major muscles. It termin...
Anatomy
null
eb7fc9fc-31e8-442d-912e-b1f598d33a5c
A 6-week baby presents with cough and cold for the past 3 days. Respiratory rate is 48/min. On examination, patient is febrile with wheezing but no chest indrawing. Which of the following is not true?
Child has pneumonia
Antibiotics are not required
Wheezing should be treated
Fever should be treated
0a
multi
This child does not have fast breathing or chest indrawing; So there is no pneumonia. Hence antibiotics are not required. But fever and wheezing should be treated. SIGNS CLASSIFY AS TREATMENT Any general danger sign or stridor in a calm child Severe pneumonia or VERY severe disease Give 1st dose of Inj. Ampicillin & Ge...
Pediatrics
Respiratory infections
144dbef5-b72b-4e56-99e6-33b7441158a0
Hyperophy is a result of
Increased production of cellular proteins
Growth factor-driven proliferation of mature cells
Reprogramming of stem cells
Decreased protein synthesis and increased protein degradation in cells
0a
single
Hyperophy refers to an increase in the size of cells, that results in an increase in the size of the affected organ. The hyperophied organ has no new cells, just larger cells. The increased size of the cells is due to the synthesis and assembly of additional intracellular structural components.HyperophyResult of increa...
Pathology
General pathology
1a93b757-b031-4b1d-b2d8-c28604e598d9
The peak level of chorionic gonadotropin in normal pregnancy occurs
30-40 days
60-70 days
10-20 days
100-110 days
1b
single
Peak maternal levels of chorionic gonadotropin in normal pregnancy occurs between 60th and 80th days after menses and is around 100,000 mIU/mL. Before 5 weeks of gestation, hCG is expressed in both cytotrophoblast and syncytiotrophoblast. Later during gestation, when maternal serum levels peak, hCG is produced almost s...
Gynaecology & Obstetrics
null
7ca88f01-529e-4f9a-a399-9b7f4732ab52
In 29 days menstrual cycle ovulation takes place at?
14th day
15th day
16th day
17th day
1b
single
ANSWER: (B) 15th dayREF: Ganong's 22nd ed p.434In a menstrual cycle the post ovulatory days remains constant, hence to calculate the day of ovulation substract 14 from the total days of cycle; i.e. in a 29 days cycle ovulation takes place on 15th day (29-14),
Physiology
Sex Hormones
c9c45703-5a05-4308-b5a0-389d18a5a009
Maximum growth spurt is seen in girls at time of –
Pubarche
Thelarche
Menarche
Adrenarche
2c
single
null
Pediatrics
null
60613e6d-0621-4a38-b312-094b07e23bc1
Fetal blood loss in abnormal cord inseion is seen in :
Vasa pre
Placenta pre
Battledore placenta
Succenturiate placenta
0a
single
Vasa Pre is usually associated with velamentous inseion when some of the fetal vessels in the membranes cross the region of cervical os and are below the presenting pa. Sometimes this can also occur with the succenturiate lobed placenta or with the marginal inseion of cord. This may be the cause for antepaum hemorrhage...
Gynaecology & Obstetrics
General obstetrics
7e5b4c14-8d83-401d-bd15-75e415d5df27
Following is not a sexual perversion ?
Sadism
Masochism
Undinism
Bestiality
3d
single
Ans. is d i.e., Bestiality
Forensic Medicine
null
986e0493-7661-4124-9752-0eae7fcf383e
Personal history includes all except:
Occupational details
Sexual history
Academic details
Food preferences
3d
multi
Ans. D. Food preferencesPersonal history includes:* Birth and early development* Education* Occupational history* Substance use* Marital & sexual history (including menstrual history)
Psychiatry
Personality Disorders
a41073c7-ec2a-476d-8dfc-b53103b08d3b
Exotropia occurs due to -
Third nerve palsy
Optic neuritis
Abducens injury
Papilloedema
0a
single
Ans. is 'a' i.e. Third Nerve Palsy Causes and associations of exotropia (Divegent squint)o Third nerve palsyo Congenitalo Previous strabismus surgeryo Thyroid ophthalmopathyo Iatrogenic trauma following retinal detachment surgery
Ophthalmology
Strabismus - Definition and Evaluation
5dcae060-6e20-47eb-8889-e2f0a014c343
A woman is exposed to a case of chicken pox 2 days back at 14 weeks of gestation. She does not give history of chicken pox in the Past. What is the next step?
Administer varicella vaccine
Administer varicella Immunoglobulin
Administer varicella Immunoglobulin and vaccine
Test mother for antibodies against varicella
3d
multi
Ans. D. Test mother for antibodies against varicellaIf the pregnant woman has antibodies against varicella, then she is immune and needs no further treatment.Exposed pregnant women who are susceptible to varicella, should be given varicella Ig within 96 hrs of exposure to prevent or attenuate varicella infection.
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
35f6fab4-5750-45c7-9be7-5e6b1c4c7cac
All are derivatives of mullarian duct except ?
Fallopian tube
Uterus
Upper 2/3rd of vagina
Lower2/3rd of vagina
3d
multi
Ans. is 'd' i.e., Lower 2/3rd of vagina PARAMESONEPHRIC DUCT (MULLERIAN DUCT) : Main genital duct in females Females Males Fallopian tubes Appendix of testis (Hydatid of morgagni) Uterus Prostatic utricle Upper 2/3 of vagina
Anatomy
null
e603a274-fe0f-49db-9e91-9f3273a90160
Which teratogen causes deafness?
Isotretinoin
Chloroquine
Alcohol
Warfarin
0a
single
Teratogenic drugs which cause deafness-. Tetracycline, minocycline, erythromycin,lsotretinoin, alcohol, phenytoin, thalidomide ESSENTIALS of MEDICAL PHARMACOLOGY SEVENTH EDITION -K D TRIPATHI Page:854 <a href="
Pharmacology
Other topics and Adverse effects
1c1f0e9f-a78a-4ea7-8f05-59e0501aa9ec
Left sided lateral gaze is affected in leasion of :
Right frontal lobe
Right occipetal lobe
Left occipetal lobe
Left frontal lobe
0a
single
A i.e. Right frontal lobe
Ophthalmology
null
94759637-40da-4224-85e5-9ad6229b844a
Which of the following drugs cause Heterochromia iridis?
Latanoprost
Prednisolone
Timolol
Olopatadine
0a
single
Ans. a. Latanoprost (Ref. Katzung 12/e p328)Latanoprost causes heterochromia iridis.Latanoprost, a stable long-acting PGF2-aIpha derivative, was the first prostanoid used for glaucoma. The success of latanoprost has stimulated development of similar prostanoids with ocular hypotensive effects, and bimatoprost, travopro...
Pharmacology
Adverse Drug Effect
a3b6e2b4-12de-4f9d-8c51-4e1947b5bb5c
The gray matter of the primary somatosensory coex contains six layers of cells. Which layer(s) receive the bulk of incoming signals from the somatosensory nuclei of the thalamus?
I
II and III
III only
IV
3d
single
Layer IV of the somatosensory coex receives the bulk of the input from the somatosensory nuclei of the thalamus. The cerebral coex contains six layers of neurons, beginning with layer I next to the brain surface and extendingprogressively deeper to layer VI. The incoming sensory signal excites neuronal layer IV first; ...
Physiology
Sensory System
0977da5d-fe8e-4781-ac74-f2cedcd79027
MARTEL'S sign is seen in
Gout
SLE
Takayasu
Kawasaki disease
0a
single
Ans. A. GoutCystic changes, well-defined erosions with sclerotic margins (often with overhanging bony edges), and soft tissue masses are characteristic radiographic features of advanced chronic tophaceous gout. Martel sign sharply marginated bony erosions from a long standing soft tissue tophus in patient with gout.
Radiology
Skeletal System
e9a2a06e-c53f-46b5-b10e-0c139df8d554
Which of the following is true regarding Umblical Cord
One artery and two veins
Presence of one vein indicates congenital anomaly
Wharton jelly is the connective tissue of the cord
Two artery only
2c
multi
Ref. Gray’s anatomy.  41st edition. Page. 179 Umblical Cord: The umbilical cord forms around the fifth week of pregnancy and can grow up to 20 inches long at full-term. Has two main layers: an outer layer of smooth muscle, and an inner layer containing a gelatinous fluid called Wharton's jelly. Vasculature - one vein...
Unknown
null
4162ead9-e02d-45d0-be10-ebc7fbd0f7a6
Relation of caudate lobe of liver is :
Posterior to poal vein
Anterior to right inferior phrenic aery
Posterior to ligamentum teres
Posterio to ligamentum venosum
1b
single
B. i.e. Anterior to . Inferior Phrenic aery
Anatomy
null
d30c4653-a359-49ee-b0fa-6c3524e53a14
Glutamine in blood acts as-
NH3 transpoer
Toxic element
Store energy
Abnormal metabolite
0a
single
Glutamine is the major form of transpo of ammonia
Biochemistry
null
2e98f427-968d-4c09-b6ca-ddc30245e686
Rakesh, a 7–year old boy had itchy, excoriated papules on the forehead and the exposed parts of the arms and legs for 3 years. The disease was most severe in the rainy season and improved completely in winter. Most likely diagnosis is
Insect bite hypersensitivity
Scabies
Urticaria
Atopic dermatitis
0a
single
Some guides have given atopic dermatitis and I would like to exclude this option first: ­ Exclusion of atopic dermatitis This child is presenting at the age of 7 years with a history of disease starting 3 years back → that means the disease was started at 4 years of age. There is involvement of the forehead (face) an...
Dental
null
02c28212-eb98-4a60-a0ff-c4b1c8f18f6b
Target strategies in preventing the HIV transmission include the following except -
Education
Treatment of STD
Anti-retroviral treatment
Condoms
2c
multi
Ans. is `c' i.e., Anti-retroviral treatment
Social & Preventive Medicine
null
4b874855-91a8-4804-9f37-7065366c8ca6
All are true about management of uterine inversion, EXCEPT?
Repositioning of uterus should be attempted immediately if diagnosed at the time of inversion
May require laparotomy
In case of delayed presentation repositioning to be attempted only after securing IV lines and adequate anesthesia
Surgical management is hysterectomy
3d
multi
MANAGEMENT OF UTERINE INVERSION Immediate management: manual repositioning, (iv access, fluid and blood for resuscitation) Delayed management: attempt manual repositioning under anesthesia (iv access, fluid and blood for resuscitation, hydrostatic method (O Sullivans) Surgical management: laparotomy f/b pulling uterus ...
Gynaecology & Obstetrics
Labour - III
fc7cbaa1-b26b-4c07-b8d6-a0ec587eb3ad
A 42-year-old man complains of head¬ache when he wakes up in the morning. It lasts into the afternoon and then subsides. Headache has been present for a few months. CT scan shows a frontal lobe mass with focal areas of calcification. You strongly suspect the pa¬tient has
An astrocytoma
A pinealoma
A meningioma
An oligodendroglioma
3d
single
A frontal headache when waking up in the morning and a computerized tomography (CT) scan showing a frontal lobe mass with focal areas of calcification are characteristic findings in oligodendrogliomas, which commonly involve the frontal lobe. These are tumors derived from oligodendrocytes that frequently locate in the ...
Unknown
null
6c37f45a-7fca-4072-93e5-8213842bed2e
Enzyme deficiency in Farber disease is
Arylsulfatase A
Sphingomyelinase
Ceramidase
Hexosaminidase A
3d
single
DiseaseEnzyme deficiencyClinical symptomsTay-Sachs diseaseHexosaminidase AMental retardation, blindness, muscular weaknessFabry diseasea-GalactosidaseSkin rash, kidney failure (full symptoms only in males;X-linked recessive)MetachromaticleukodystrophyArylsulfatase AMental retardation and psychologic disturbances inadul...
Biochemistry
Enzymes
93544cb1-a6d4-448c-a11b-5ecfea1f8823
Which of the following is present in skeletal muscle?
GLUT 4
GLUT 5
GLUT 7
GLUT 2
0a
single
GLUT-4 is present in peripheral tissues (skeletal muscles, cardiac muscles, adipose tissues). Table: Location and function of various GLUTs LOCATION FUNCTION GLUT-1 Brain, Placenta, Kidney, RBC Glucose uptake during fasting GLUT-2 Liver, Pancreas, Intestine Liver-glycogen formation pancreas-insulin secretion GLUT-3 Bra...
Biochemistry
FMGE 2019
9b8b7b46-3058-47db-84df-2ae4ead08072
Erysipeloid is transmitted by which of the following route
Droplet
Mosquito bite
Fish
Feco-oral
2c
single
Erysipeloid (Fish Handler's Disease) * Infection caused by Erysipelothrix rhusiopathiae through direct contact with infected meat, seen mainly in meat-handlers, fisherman or veterinarians. * Presents with painful red to purple patches over hands (finger webs often involved, sparing terminal phalanges) with sharply-marg...
Dental
Bacterial infections
3a170ad4-df24-40f6-a7df-c00e93c4d4a9
A subtype of Hodgkins which is histogenetically distinct from all others
Lymphocyte predominant
Nodular sclerosis
Mixed cellularity
Lymphocyte depleted
0a
multi
Nodular Lymphocyte-Predominant Hodgkin's Lymphoma It is now recognized as an entity distinct from classical Hodgkin's lymphoma. Asubset of these patients has tumors with nodular growth pattern and a clinical course that varied from that of patients with classical Hodgkin's lymphoma. This is an unusual clinical entity a...
Pathology
General pathology
a054a69f-5fdc-4d6a-b158-26d878e4efab
Which of the following is not a suppo of the uterus?
Urogenital diaphragm
Pelvic diaphragm
Perineal body
Rectovaginal septum
3d
single
(Refer: Gray's Anatomy, 40th Edition, Chapter. 77)
Anatomy
All India exam
5d47d2b5-dfcf-4b36-970d-5321a26936e2
Koebner's phenomenon seen in ?
Psoriasis
Lichen nitidus
Vitiligo
All the above
3d
multi
Ans. is `d' i.e., All the above See explanation- 2 of session- 1 of Skin of All India 2014-15 pattern of this book.
Skin
null
3f996dd3-1cd3-495c-9de6-2e110978fd48
In a clinical trial, blood pressure was measured in a group of patients before and after treatment, which of the following tests will be suitable as a test of significance:
Paired t-test
Mann-Whitney U test
Student t-test
ANOVA
0a
single
Ans. A. Paired t-testUnpaired t-test (aka Students test) compares two different subjects. The paired t-test reduces intersubject variability (because it makes comparisons between the same subject), and thus is theoretically more powerful than the unpaired t-test.In our case, we are analyzing the same subject twice (tha...
Social & Preventive Medicine
Biostatistics
b73c3dcd-707f-4e45-a620-004d2482bb36
A newborn baby was born with phocomelia. It results due to which drug taken by mother during pregnancy
Tetracycline
Thalidomide
Warfarin
Alcohol
1b
single
Ans. (B) Thalidomide(Ref: KDT 8th/e p100)Thalidomide is highly teratogenic drug that can result in phocomelia as congenital anomaly.
Pharmacology
General Pharmacology
8964fedc-83d1-4d1b-b982-69d09366b9f6
Patient is being treated with clomiphene for infertility, method of choice to look for ovulation is -
Serial ultrasound
Chest X-ray
Serial HCG
None
0a
multi
Ans. is 'a' Serial ultrasound (Ref. Shaws, 13/e, p 305 (12/e, p. 242)).In patients with infertility and being treated with clomiphene monitoring of Graafian follicle is required to check its maturity and to detect imminent ovulation.This monitoring is done with serial ultrasound starting from day 10th to day 16th.It is...
Gynaecology & Obstetrics
Pathology of Conception
b4d1b5ca-04e6-4592-aedd-ee47c04b507e
To cause hemorrhagic shock, least volume of blood loss should be:
30%
40%
20%
50%.
2c
single
Ans: C (20%) Ref: Klingensmith ME, Chen LE, Glasgow SC, Goers T4. Melby SJ, Reticular Formation, EEC and sleep. In: Washington Manual of Surgery. 5th Edn, Lippincott Williams & Wilkins 2008; 7: 145Explanation: (See the following table)
Physiology
Circulation: Circulatory Shock and Its Treatment
b4efadc1-11f3-4188-9188-8fb42af4b49e
The water channel presented in proximal convoluted tubule is:
Aquaporin 1
Aquaporin 2
Aquaporin 5
Aquaporin 9
0a
single
Rapid diffusion of water across cell membranes depends on the presence of water channels, integral membrane proteins called aquaporins. Aquaporin-1 is localized to both the basolateral and apical membrane of the proximal tubules and its presence allows water to move rapidly out of the tubule along the osmotic gradients...
Physiology
null
9c66fdaf-aacb-4af6-a448-a8c9fd599383
Clara cells are seen in -
Alveoli
Bronchus
Trachea
Bronchiole
3d
single
Ans. is 'd' i.e., Bronchioles o Clara cells are small dome shaped cells present in terminal bronchioleo They secrete a protein that lines the small air passages.
Anatomy
Respiratory System (Histology)
d45eba0a-b3e9-4f72-990d-8ee040c34103
Child can Swaps object from one hand to other in:
2-3 month
5-6 month
6-12Months
12-18 Months
1b
single
Ans. b. 5-6 monthChild can transfer objects from one hand to other by 6-7 monthTransfer objects hanil to hanil in 5'5 months
Pediatrics
null
05d951e6-48e2-4e75-9ed5-b7e7a7734621
How will you differentiate a mediastinal mass being a thymoma or ALL?
Cytokeratin
CD1a
Cd3
Tdt
0a
multi
Marker specific for thymoma is Cytokeratin Other markers for thymoma include : P 63, PAXp-8 . Most sensitive and specific marker for thymoma is FOXN 1 Markers common for both thymoma and T-ALL include: CD1a CD3 TDt Marker specific for thymoma is Cytokeratin Other markers for thymoma include : P 63, PAXp-8 . Most sensit...
Pathology
Acute Lymphoblastic Leukemia
d1a01001-d053-4788-9c55-027cb7b61a73
The main component of hyperlipidemia constituting a major risk factor for atherosclerosis is
high density lipoprotein (HDL) cholesterol
intermediate density lipoprotein (IDL) Cholesterol
low density lipoprotein (LDL) cholesterol
very low density lipoprotein (VLDL) cholesterol
2c
single
null
Medicine
null
d69c449e-de8e-492d-90c8-232421cc9ded
Features of Giardiasis -
Mal absorption
Cyst with 4 nuclei
Trophozoite with four nuclei
Common in hypogammaglobulinemia
0a
single
Giardiasis Infection with Giardia lamblia is found worldwide and is common in the tropics. It paicularly affects children, tourists and immunosuppressed individuals, and is the parasite most commonly impoed into the UK. In cystic form, it remains ble in water for up to 3 months and infection usually occurs by ingesting...
Medicine
Infection
19ab4837-0560-453c-b675-c1ca09a258e4
Which one of the drugs is useful in treating Crohn's disease ?
Infliximab
Azathioprine
Tacrolimus
Cyclosporine
0a
single
null
Pharmacology
null
cf4382aa-ae9e-4d09-b534-5d10792d9343
45 year old patient develops nausea,vomiting and ascending paralysis on ingestion of broken seeds from a plant. What could be the active present in that seed?
Atropine
Strychnine
Ricin
Bhilawanol
1b
single
Strychnos Nux vomica is a spinal poison unbroken seeds are not poisinous. The above clinical features are characteristic of strychnine poisoning.
Forensic Medicine
null
cc3e84c5-e949-4e85-b7b7-c833a836179d
All are minor Jones criteria except -
Arthralgia
Fever
Prolonge PR interval
Chorea
3d
multi
Ans. is 'd' i.e., Chorea Guidelines for the Diagnosis of Initial Attack of Rheumatic Fever (Jones Criteria, Updated 1992) Major Manifestations Minor Manifestations Supporting evidence of antecedent group A streptococcal infection Carditis Clinical features: Positive throat culture or rapid streptococcal antigen test Po...
Unknown
null
7459464c-7cda-4a5c-8700-94c24e9ef6be
Reliability of screening test does not mean -
Reproducibility
Repeatability
Validity
Precision
2c
single
Ans. is C Validity Screening test to be applied o The screening test to be applied should fulfill the following important criteria before it is considered suitable for screening : - 1 .Acceptability The test should be acceptable to the people at whom it is aimed. In general painful or embarrassing tests e.g., per recta...
Social & Preventive Medicine
Screening for Disease
1e652061-38e2-4c9e-b879-b24bb0359861
True about H mole:a) Always associated with raised uterine size for gestational ageb) Raised hCGc) Hysterectomy in selected casesd) Chemotherapy is the treatment of choicee) Thyrotoxicosis rare
ab
bc
bce
ace
2c
multi
Lets have a look at each option separately - Option ‘a’: Always asociated with raised uterine size for gestational age. This statement is incorrect as : “The size of the uterus is more than that expected for the period of amenorrhea in 70%, corresponds with the period of amenorrhea in 20% and smaller than the period of...
Gynaecology & Obstetrics
null
d77b0dd5-13ac-4a87-8861-615738081b32
Bioterroism group A agent
Q fever
Typhus fever
Brucella
Antrax
3d
single
Ans. is 'd' i.e., Antrax Bioterrorismo A bioterrorism attack is the delibrate release of viruses, bacteria or other germs (agents) used to cause illness or death in people, animals or plants. These agents are typically found in nature, but it is possible that they could be changed to increase their ability to cause dis...
Microbiology
Bacteria
3a721b2c-ee4f-4acf-8ff0-d307e11862f9
To look right & left which type of joint is involved
Ellipsoid joint
Pivot joint
Saddle joint
Hinge joint
1b
single
Ans: B. Pivot jointRight to left movement occurs at atlanto-axial joint which is a pivot joint.
Anatomy
null
3e7fa273-5b30-410e-b97e-3571eab87961
In Schwann cells, mycobacterium leprae divide in how many days?
2 - 3 days
11 - 13 days
22 - 23 days
32 - 33 days
1b
single
.
Pathology
All India exam
802a2c2d-b722-4407-9428-ad7bd43e53e9
The commonest anatomical position of appendix is
Retrocaecal
Pelvic
Paracaecal
Preileal
0a
single
A. i.e. Retrocaecal- Vermiform appendix develops from midgut loops, is supplied by appendicular branch of ileocolic aery. It has mesoappendix (mesentery) but no teniaMost common posiion of vermiform appendix is retrocecal (12 o'clock = 65%) followed by pelvic or 4 o'clock positions
Anatomy
null
8994c4c6-4abf-4fd7-a315-aeff7b205c68
What is the optimum duration antibacterial treatment of acute bacterial prostatitis?
3 days
4-6 weeks
7-14 days
2-14 days
1b
single
The choice of antibiotic for treatment of acute bacterial prostatitis (ABP) is based on the results of the initial culture and sensitivity. However, initial therapy should be directed at gram-negative enteric bacteria. Useful agents include fluoroquinolones, trimethoprim-sulfamethoxazole, and ampicillin with gentamicin...
Surgery
Urology
1b7e02a2-f110-4aec-a932-c533cdc4d2c7
D2O is used to measure
ECE Volume
ICF volume
TBW volume
Plasma volume
2c
single
The concentration of the marker in the plasma is measured and from this value, the total body water can be measured. The markers are D2O, tritium oxide, aminopyrine.(Ref: Textbook of medical physiology N Geetha 2nd edition page no.61)
Physiology
General physiology
e45da1d0-3b72-4c9c-b4e2-23892a992ca1
A 13-year-old young girl presents in the casualty with acute pain in the lower abdomen. She has history of cyclical pain for last 6 months and she has not attained her menarche yet. On local genital examination, a tense bulge in the region of hymen was seen. The most probable diagnosis is:
Mayer Rockitansky Kuster Hauser syndrome
Testicular feminization syndrome
Imperforate hymen
Asherman's syndrome
2c
single
Ans. is c, i.e. Imperforate hymenRef: Shaw 15th/ed, p96-97A young girl who has not attained menarche but has history of cyclical pain for last 6 months, presenting to casualty with acute abdomen and on examination a tense bulge in the region of hymen - clearly point towards "Imperforate hymen" as the diagnosis.
Gynaecology & Obstetrics
Disorders in Menstruation
332b332d-69a1-4ed4-aab4-e1e15214ad24
Fern test is due to :
Presence of NaCI under progesterone effect
Presence of NaCI under estrogenic effect
LH/FSH
Mucus secretion by Glands
1b
single
Ans. is b i.e. Presence of NaCI under estrogenic effect Fern test is for documenting ovulation. Procedure : A specimen of cervical mucus is obtained and is spread on a clean Glass slide and allowed to dry. It is then viewed under the low power microscope. Result and interpretation : Under the influence of estrogen on D...
Gynaecology & Obstetrics
null
ec5294be-01e7-4b56-a8da-87f9b015aee2
A 28-year-old G1P0 at 32 weeks gestation present with itchy, erythematous papules on the extensor surfaces and trunk. . No history of fever or use of new creams or lotion was given. What is first line treatment for this condition?
Antibiotic therapy
Antivirals and termination of pregnancy
Topical steroids and oral antihistamines
Oral steroids
2c
single
This lesion isPruritic uicarial papules and plaques of pregnancy (PUPPP) or prurigo pf pregnancy. Characterized by 5- to 10-mm, itchy, erythematous papules or nodules commonly found on the extensor surfaces and trunk Prurigo of pregnancy resolves after delivery of the baby. However, resolution can take as long as sever...
Gynaecology & Obstetrics
Medical Illness Complicating Pregnancy
b3d8ee67-06a6-49d3-964d-7b66d5b79dfb
Familial amyloidotic polyneuropathy is due to amyloidosis of nerves caused by deposition of ?
Amyloid associated protein
Mutant Calcitonin
Mutant Transthyretin
Normal transthyretin
2c
single
Ans. is 'c' i.e., Mutant transthyretinTransthyretin (ATTR) amyloid Transthyretin (TTR) is normal serum protein that binds and transpo thyroxine and retinol.o TTR can cause following types of amyloidosis : ?1. Mutant TTR : - Mutation in TTR can cause syndrome of familial amyloidotic polyneuropathy or familial amylodotic...
Pathology
null
7d441343-777a-4209-9f07-05860288a651
Hutchinson's rule is related to ?
Herpes simplex keratitis
Mycotic keratitis
Herpes zoster ophthalmicus
None
2c
multi
Ans. is 'c' i.e., Herpes zoster ophthalmicus Hutchinson's rule : - In herpes zoster ophthalmicus, involvement of the tip of nose, supplied by external nasal nerve (a terminal branch of nasociliary nerve), signifies increase risk of ocular involvement (uveitis).
Ophthalmology
null
04da575c-3116-4c63-b45a-f2e5de45c837
The rectus sheath contains all of the following except
Pyramidalis muscle
Genitofemoral nerve
Inferior epigastric vessels
Superior epigastric vessels
1b
multi
The rectus sheath is formed by the aponeuroses of the transverse abdominal and the external and internal oblique muscles. It contains the rectus abdominis and pyramidalis muscles. It can be divided into anterior and posterior laminae. <img src=" /> Ref - BDC 6e Vol2 pg209
Anatomy
Abdomen and pelvis
e4a9c97a-6004-4af1-8994-06e58bfcd919
Iron absorption is decreased by A/E-
Calcium
Tetracycline
Phytate
Ascorbic acid
3d
single
Ans. is 'd' i.e., Ascorbic acid
Pathology
null
44a81232-4761-4a03-b0b8-b74478d1ef64
The usual maximum dose of furosemide and spironolactone in patients with cirrhosis and poal hypeension is:
Furosemide 160 mg and spironolactone 400 mg
Furosemide 80 mg and spironolactone 400 mg
Furosemide 160 mg and spironolactone 200 mg
Furosemide 80 mg and spironolactone 200 mg
0a
single
Usual maximum doses of diuretic for the treatment of ascites in decompensated cirrhosis are 400 mg/day of spironolactone and 160 mg/day of furosemide. Furosemide can be temporarily withheld in patients presenting with hypokalemia, which is very common in the setting of alcoholic hepatitis. Ref: HEPATOLOGY, June 2009.
Pharmacology
null
a55393f2-bc2a-4885-a21c-caf82ad429b3
Major contribution to cachexia with advanced cancer-
Clathrin
Histamine
Nutritional demands of cancer
Tumor-necrosis-factor (TNF)
3d
single
Cachexia is not caused bu nutritional demands of the tumor. It is suspected that TNF produced by macrophages in response to tumor cells or by the tumor cells them self mediate cachexia. TNF mobilize fat from tissue stores and suppress appetite. ROBBINS
Pathology
General pathology
568d8b8c-78e8-4980-ac14-a2171998b68a
Which of the following is the rarest modification in a fibroid uterus :
Red degeneration
Calcification
Hyalinization
Sarcomatous changes
3d
single
Sarcomatous changes
Gynaecology & Obstetrics
null
8ec8010c-7210-4b3c-9e26-541c020cd9b0
Prehn sign is seen in
Acute orchitis
Chronic orchitis
Testicular torsion
None
2c
multi
Prehn's sign - elevation of the scrotum for 1 hr relieves the pain of acute epididymo-orchitis but aggrevates the pain in case of torsion testis . Reference : page 1082 SRB's manual of surgery 5th edition
Surgery
Urology
1ade9c5a-380e-41c2-ad73-697582c4dae5
Berkesonian bias refers to
Different rates of admission to the hospital
Interviewers bias
Reduces bias
Systematic difference in characteristic cases and controls
0a
single
Ans. is 'a' i.e., different rates of admission to the hospital Bias is any systematic error in the determination of the association between the exposure and diseaseMany varieties of bias are seen: a) Bias due to confounding : This bias arises because of the confounding factors."A confounding factor is defined as one wh...
Social & Preventive Medicine
Epidemiological Study
15ad5cd9-8e06-4fa0-a149-ef1073adecd9
Males are more commonly affected than females in-
Autosomal dominant
Autosomal recessive
X- linked dominant
None of these
2c
multi
Most X-linked disorders are X-linked recessive and are characterized by the following features: They are transmitted by heterozygous female carriers only to sons, who of course are hemizygous for the X chromosome. Heterozygous females rarely express the full phenotypic change, because they have the paired normal allele...
Pathology
General pathology
6f360145-de81-4019-9765-d377d8c024d1
Antiparkinson drug known to cause cardiac valvular fibrosis is ?
Levodopa
Ropinrole
Pramiprexole
Pergolide & cabergo line
3d
single
Ans. is 'd' i.e., Pergolide & cabergoline o Ergot-containing dopamine receptor agonists used for Parkinson's disease (pergolide, cabergoline, bromocriptine) cause valvular hea disease that closely resembles that seen in the carcinoid syndrome. o Metabolites of fenfluramine, as well as the dopamine receptor agonists, ha...
Pharmacology
null
8742c726-03a6-46aa-aaef-fe40b579114c
Ring of Soemmering is seen in –
Galactosemia
Dislocation of lens
Acute congestive glaucoma
After cataract
3d
single
Ring of sommerring and Elsching's pearls are seen in after cataract.
Ophthalmology
null
b91f2274-0ea9-4a1d-90a5-497dc33133ed
Most common brain tumour is-
Astrocytoma
Meningioma
Metastasis
Oligodendroma
2c
single
Ans. is 'c' i.e., Metastasis o MC brain tumors-Metastaseso MC primary brain tumor-Gliomao MC Glioma-Astrocytomaso MC Astrocytomas-Glioblastoma multiforme
Surgery
Central Nervous System Tumors
2915b15f-cb0e-49ad-8d4e-c5f1bde92a25
"Limey bile" is?
Present in the CBD
Thin and clear
Like toothpaste emulsion in the gall bladder
Bacteria rich
2c
multi
Ans. (c) Like toothpaste emulsion in the gall bladderRef: Harrison 18th ed/2622* It is a complication of chronic cholecystitis.* Calcium salts in the lumen of the gall bladder in sufficient concentration may produce calcium precipitation and diffuse, hazy opacification of bile or a layering effect on plain abdominal ra...
Surgery
Miscellaneous (Gall Bladder & Bile Ducts)
db5f5891-c5ed-4747-9f58-95a82f1f14b0
RDA of zinc in a child less than 8 years old is-
5 mg
12 mg
20 mg
25 mg
0a
single
Ans. is 'a' i.e., 5 mg RDA of Zinc in children* 1-3 years- 3mg* 4-8 years- 5 mg* 9 years and above (male)- 8-11 mg* 9 years and above (female)- 8 mg
Pediatrics
Nutrition
985d9850-68f7-4b7e-ba19-d33216cb3948
Before the onset of pubey, the GnRH neurons are under the inhibitory control of:
Glycine
Glutamate
Gamma amino butyric acid (GABA)
Beta-endorphin
2c
single
The transition to a reproductive state (during pubey) requires maturation of the entire hypothalamic-pituitary-gonadal axis. Before this maturation occurs, plasma LH and FSH levels are diminished despite low concentrations of gonadal steroids and inhibin. GnRH neurons are said to be under inhibitory influence of GABAer...
Physiology
Female Reproductive System