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135
8b2bd963-c517-43bc-82d6-1bd5ed9a2131
Therapeutic indications of Laparoscopy in gynecology are all except
Vault prolapse
Septate uterus
Gamete intrafallopian transfer
None of the above
3d
multi
All of the options are therapeutic indications of Laparoscopy.
Gynaecology & Obstetrics
null
9c67acc7-bfc0-4db1-bb3a-016f960d3c30
Which of the follwing patients is most likely to be treated with intravenous glucagon?
A young man who took cocaine and has a blood pressure of 190/110 mm Hg
A middle aged man with type II diabetes who has not taken his regular dose of glipizide for last 4 days
An old man with severe bradycardia and hypotension resulting from ingestion of overdose of atenolol
An old woman with lactic acidosis as a complication of severe infection and shock
2c
single
(Ref: KDT 6/e p274) Glucagon is the antidote of b-blocker poisoning. It acts by increasing cAMP in the hea stimulation of glucagon receptors. Cyclic AMP stinulates the hea. Calcium gluconate can also be used for the treatment of b-blocker poisoning.
Anatomy
Other topics and Adverse effects
e66b836f-18bd-4821-be55-22046bf38e66
Clinical findings suggestive of adequacy of pelvis for vaginal delivery are all except?
Diagonal conjugate > 11.5 cm
Interspinous diameter > 8 cm
Sacrosciatic notch 2.5 - 3 finger breadths
Bituberous diameter > 8 cm
1b
multi
Ans. is 'b' i.e., Interspinous diameter > 8 cmClinical findings suggestive of adequacy of pelvis for vaginal delivery are:Findings indicating adequate pelvisForepelvis (pelvic brim)RoundDiagonal conjugate11.5 cmSymphysisAverage thickness, parallel to sacrumSacrumHollow, average inclinationSide wallsStraightIschial spin...
Gynaecology & Obstetrics
null
91ba8dfb-2792-4c2d-aa58-523f9948121e
All of the following is an example of squamous metaplasia except:
Cervix in case of chronic irritation
Respiratory tract in case of smoking
Stone in bile ducts
Esophagus in gastric reflux
3d
multi
In Barrett esophagus, in which the esophageal squamous epithelium is replaced by intestinal-like columnar cells under the influence of refluxed gastric acid. Options analysis Cervix in case of chronic irritation show squamous metaplasia The most common epithelial metaplasia is columnar to squamous as occurs in the resp...
Pathology
General Concepts
be6d7c9b-c11a-4f96-baf7-6c8ec864859b
A farmer working in the sugar cane industry comes to you for advice on how to prevent fungal infection (bagassosis) of the lung. His elder brother was diagnosed to have bagassosis 1 month ago. You would advise him to spray the sugar cane with which of the following?
2% formic acid
2% acetic acid
2% propionic acid
10% hypochlorite solution
2c
single
Bagassosis is caused due to thermoactinomyces sacchari. The preventive measures include dust control, personal protection using masks etc. Pre Placement medical assessment followed by periodical medical check up and spraying the bagasse with 2% propionic acid. Keeping the humidity over 20% is also helpful. Ref: Park, E...
Social & Preventive Medicine
null
624eabda-fad5-4cf9-b1b6-f2de0e113108
The ovoviviparous nematode is -
Ascaris lumbricoides
Dracunculus medinensis
Strongyloides stercoralis
Enterobius vermicularis
2c
single
null
Microbiology
null
f1d3e6c0-4bca-4871-8a2d-511d6388b07e
For obesity BMI should be:-
>=20
>=40
>=50
>=30
3d
single
park25th edition pageno:-428 classification BMI RISK OF COMORBIDITIES UNDERWEIGHT <18.5 LOW NORMAL RANGE 18.5-24.99 AVERAGE OVERWEIGHT: >25.00 Pre- obese 25.00-29.99 INCREASED Obese class 1 30.00-34.99 MODERATE Obese class 2 35.00-39.99 SEVERE Obese class 3 >40.00 VERY SEVERE
Social & Preventive Medicine
Non communicable diseases
9e2ce523-b8f5-4a0b-8b9f-7c8fc2c0269d
Alloyed form of direct gold restoration is:
Goldent
Mat gold
Electralloy
laminated gold foil
2c
multi
null
Dental
null
65559d27-f1a0-4efa-8b4f-809a64beeec8
All the following are used in a patient with decreased renal function (reduced GFR) in order to avoid contrast nephropathy except
N-acetyl cysteine
Mannitol
Fenoldopam
Low osmolar contrast media (LOCM)
1b
multi
.
Medicine
All India exam
797d94e2-f414-44f6-ae32-dc61e2b1c172
A chronic alcoholic develops palpitations suddenly after alcohol binge. His pulse is irregularly irregular Which of the following arrythmia is most commonly associated with alcohol binge in the alcoholics ?
Ventricular fibrillations
Vetricular premature contractions
Atrial flutter
Atrial fibrillation
3d
single
Atrial fibrillation (AF or A-fib) is an abnormal hea rhythm characterized by rapid and irregular beating of the atrial chambers of the hea. Often it stas as brief periods of abnormal beating which become longer and possibly constant over time.Often episodes have no symptoms. Occasionally there may be hea palpitations, ...
Medicine
C.V.S
b44a245c-1999-4d0b-9d5a-d7666b5386ef
Treatment of papillary carcinoma thyroid with level VI lymph node metastasis is
Total thyroidectomy
Total thyroidectomy + central neck dissection
Total thyroidectomy + radioiodine ablation
Total thyroidectomy + radical neck dissection
1b
single
IF level VI is affected then CND is done. If any other LN is involved then modified radical neck dissection is preferred.
Surgery
null
b41511ba-0d61-4f5d-a429-7cc217893f71
Shortest acting Mydriatic and Cycloplegic is
Atropine
Phenylephrine
Tropicamide
Homatropine
2c
single
Shortest acting Mydriatic and Cycloplegic is Tropicamide. Phenylephrine is only mydriatic with no cycloplegic property.
Ophthalmology
null
2220bc6a-5a32-4218-86e5-29feede57da0
Acute flaccid paralysis is repoed in a child aged -
0-3 years
0-5 years
0-15
0-25 years
2c
single
- one of the strategy for polio eradication in India is improving surveillance capable of detecting all cases of AFP due to prohibit non polio etiology. - AFP surveillance is done in all children below age of 15 years. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:208,209 <\p>
Social & Preventive Medicine
Communicable diseases
885bfbf4-5519-4ce9-8205-5762fc925230
Which of the following does not stimulate enterogastric reflex?
Products of protein digestion in the duodenum
Duodenal distension
H+ ions bathing duodenal mucosa
Cholecystokinin
3d
single
Enterogastric reflex: signals from the colon and small intestine to inhibit stomach motility and stomach secretion.The types of factors that are continually monitored in the duodenum and can initiate enterogastric inhibitory reflexes include the following:1. Distention of the duodenum2. The presence of any irritation o...
Physiology
General physiology
b6f530fe-e5db-4a7e-a569-ed1d4944ee4c
Which pa of orbicularis oculi is known as Horner's muscle:
Orbital
Lacrimal
Temporal
Muller's muscle
1b
single
Ans. Lacrimal
Ophthalmology
null
3b6201fa-84c9-467b-a265-832bf5df87b1
Thrombotic event is seen in all of the following, except:
Paroxysmal nocturnal hemogloninuria
Disseminated intravascular coagulation
Immune thrombocytopenic purpura
Heparin induced thrombocytopenia
2c
multi
Primary or idiopathic ITP -Two clinical subtypes: acute and chronic. -Both are autoimmune disorders in which platelet destruction results from the formation of antiplatelet autoantibodies. -Associated with increased bleeding tendency and not thrombosis. PNH The triad of hemolysis, pancytopenia, and thrombosis is unique...
Pathology
Bleeding disorder
0800aad7-0d48-4d81-b2e8-9d891a91048c
Maternal Rubella, in newborn causes all Except
Neural tube defects
CVS defects
Cataract
Deafness
0a
multi
Rubella - Postnatal infectionComplications of Rubella*Rash spreads from head to torso & extremities.*Forschheimer spots-petechiae haemorrhages on the soft palate.*Rash duration -3 days.*Suboccipital adenopathy.*MC test - IgM Rubella ELISA*Post infectious thrombocytopenia.*Self-limiting small joint ahritis in adults.*Po...
Anatomy
All India exam
2e0cf44a-6ec9-48f0-89b6-331496323052
Eruption of temporary teeth will be completed by :
One to one and half year
Two to two and half year
Three to four years
Four to five years
1b
single
B i.e. 2-21/2 years
Forensic Medicine
null
48bef5bf-face-4d48-a661-dbe5d61ddea8
Substance which binds to substrate other than catalytic enzyme is ?
Competitive inhibitor
Non-competitive inhibitor
Reversible inhibitor
None of the above
1b
multi
Ans. is 'b' i.e., Non-competitive inhibitor Non-competitive inhibitor In this type of inhibition no competition occurs between substrate and inhibitor. Inhibitor is structurally different from substrate and binds to enzyme at a site other than the substrate binding (catalytic) site. Occupancy of this site by the inhibi...
Biochemistry
null
b1b311ba-3c00-42ea-8254-e95817151f7c
Most common type of monozygotic twin pregnancy at 4th-8th day of cell division
Monochorionic Monoamniotic twins with Siamese presentation
Monochorionic Monoamniotic(MO-MO) twins
Monochorionic Diamniotic twins(MO-DI)
Dichorionic Diamniotic twins (DI-DI)
2c
single
In monozygotic twins, chorionicity depends upon time of cell division. Time of cell division Chorionicity of placenta First 72 hours post feilization(morula stage) DCDA 4-8th day(blastocyst stage) MCDA(MC type of monozygotic twins) 8-12th day MCMA >12th day Conjoined/Siamese twins, type of MCMA(fusion of embryonic disc...
Gynaecology & Obstetrics
Twin Pregnancy, Molar Pregnancy, Gestational Trophoblastic disease and contraception in special situations (Sour Grapes!)
b92007f3-02cd-4d4b-bf8b-105469778ae6
Average head circumference at bih is ?
35 cm
40 cm
45 cm
50 cm
0a
single
O.P. Ghai 9th ed, page 14 Beginning at 34 cm at bih, the head circumference increases approximately 2 cm per month for first 3 months, 1 cm per month from 3-6 months and 0.5 cm per month for rhe rest of the first year of life.
Anatomy
General anatomy
428da784-4c1e-4200-858c-a0ab6a8d7ba9
Cornea melts without inflammation in which condition -
Gout
Sarcoidosis
Keratomalacia
Rheumatoid arthritis
2c
single
Keratomalacia It is a common condition in developing countries and is due to deficiency of vitamin A.   The condition is usually bilateral. In keratomalacia, the cornea becomes dull and insensitive, hazy and yellow infiltrates form until finally the whole tissue undergoes necrosis and seems to melt away within a few h...
Ophthalmology
null
de06b2f5-869c-4164-bd32-e0b7467556a3
Select the drug which is neither analgesic, nor anti- inflammatory, nor uricosuric, but is highly efficacious in acute gout
Colchicine
Sulfinpyrazone
Naproxen
Prednisolone
0a
single
Colchicine Colchicine is neither analgesic nor anti- inflammatory, but it specifically suppresses gouty inflammation. It does not inhibit the synthesis or promote the excretion of uric acid. Thus, it has no effect on blood uric acid levels. pathophysiology of gout:- An acute attack of gout is staed by the precipitation...
Pharmacology
Autacoids
3b9855e8-5d2c-42fe-9beb-3b2eaa4beaf4
The following are characteristic of tumour lysis syndrome except -
Hyperkalemia
Hypercalcemia
Hyperuricemia
Hyperphosphatemia
1b
multi
Tumour Lysis Syndrome More common with NHL, Myeloma and acute leukaemia management Rapid tumour cell death releases intracellular contents resulting in hyperkalaemia, hyperphosphataemia, hyperuricaemia and renal failure. Prevention is with adequate hydration and Allopurinol 300-600 mg QID PO Sodium bicarbonate 50 mEq/L...
Medicine
Endocrinology
15a3373f-f276-457d-99ed-dbec6054279f
Which of the following interactions contributes most to protein folding
Covalent Bond
Ionic interactions
Hydrophobic
Vander waal's interaction
2c
single
Protein folding: *The number of distinct combinations of phi and psi angles specifying potential conformations of even a relatively small-- 15 kDa--polypeptide is unbelievably vast, native conformation is specified in the primary sequence. In nature, protein folding takes place in a more orderly and guided fashion.*Pro...
Biochemistry
Metabolism of protein and amino acid
b04715f9-d7d8-4edd-aeac-09c13d0a4ca5
Receptor of EBV is
CR1
CR2
CD20
CD19
1b
single
EBV binds to CD21 or CR2 receptor.
Microbiology
null
09111550-20bf-4d2d-9d20-6404f2b2e052
Non immune hydrops is seen in?
Alpha thalassemia major
Rh incompatibility
Bilateral renal agenesis
Maternal rubella
0a
single
Alpha thalassemia major REF: Fetology: diagnosis and management of the fetal patient by Diana W. Bianchi, Timothy Crombleholme, Mary E. D'Alton Page 893, http://en.wikipedia.org/wiki/Hydrops_fetalisImmune_causes Non-Immune causes of Hydrops The non-immune form of hydrops fetalis has many causes including: Iron deficien...
Pediatrics
null
8db3d3bb-46b7-493d-a700-e342cd389ca5
DOC in primary syphillis is –
Corticosteroid
Oral penicilline
Benzathine penicilline
Crystalline penicilline
2c
multi
Benzathine penicillin is the drug of choice for primary, secondary, latent and tertiary syphilis (except for neurosyphilis). For neurosyphilis aqueous penicillin G is the drug of choice.
Dental
null
ce164c11-db6f-4a13-b8c5-d45962b7662a
Lithium is not used in the treatment of which of the following
Major depression
Vascular headache
Neutropenia
Generalized anxiety disorder
3d
single
uses of lithium is impoant it is used in several disorders like vascular headache mania depression drug induced neutropenia suicidal ideas in mania Ref.Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 983
Psychiatry
Pharmacotherapy in psychiatry
3934108c-b745-4d0c-970c-30779541fceb
About HUS all are true except :
Not commonly caused by verocytogenic E coli
Causes mild to severe Coombs positive hemolytic anemia
Recurrences rare
Transient thrombocytopenia
1b
multi
Causes mild to severe Coombs positive hemolytic anemia Hemolytic-uremic syndrome (H.U.S.) is the most common cause of acute renal failure in young children. It is classically characterized by the triad of - Microangiopathic hemolytic anemia - Thrombocytopenia - Uremia Etiology Hemolytic uremic syndrome is preceeded by ...
Microbiology
null
65da98cc-4798-44be-8ee6-5d548629c208
Features of diabetic nonproliferative retinopathy are all except-
Neovascularisation
Soft exudates
Microaneurysms
IRMA
0a
multi
Diabetic retinopathy is classified into two stages: nonproliferative and proliferative. Nonproliferative diabetic retinopathy usually appears late in the first decade or early in the second decade of the disease and is marked by retinal vascular microaneurysms, blot hemorrhages, and cotton-wool spots (soft exudate). Mi...
Medicine
Endocrinology
aa37a2e2-a3b6-4b67-80da-d0c014d808ec
Anti tobacco day is:-
1-Jul
24-Mar
31-May
1-Dec
2c
single
31 may: Anti-tobacco day 1 july: doctor's day 24 march: anti TB day 1 december: World AIDS day
Social & Preventive Medicine
Health Schemes
36143579-d330-4098-90ab-8617579fa03a
WHO Malaria Mass Drug Administration ?
API >5
> 2
15
25
1b
single
Ans. is 'b' i.e., >2 First you should know what does mass prophylaxis mean in malaria. o In areas with high malaria prevalence, presumptive treatment is given to all people. This is know as mass treatment. Presumptive treatment is given when API is >2 (see above explanation).
Social & Preventive Medicine
null
76c5b79d-efaa-4820-a365-ec33c2f4cff6
Which of the following sequence is directed in a retrograde manner to EPR in COP-1 vesicles?
KDEL
KDAL
DALK
KDUL
0a
single
KDEL sequence ( lysine - aspaate - glutamate - leucine ) at carboxy terminal first travel to GA in COP-2 vesicles, interact with their specific receptor protein. then they return in a COP-1 vesicle to EPR, get dissociate from their receptor & are retrieved. Reference: Harper; 30th edition
Biochemistry
Structure and function of protein
bc719075-445f-4f04-a449-c433c2ea1d06
All are been in Pancoast syndrome except
Brachial plexus involvement
Dyspnoea
Clubbing
Myasthenia gravis
3d
multi
Pancoast tumour invades brachial plexus,sympathetic chain,upper ribs,and veebrae.Dyspnoea can occur due to loss of functioning lung tissue/the development of a large pleural effusion.Clubbing and hyperophic pulmonary osteoahropathy can also occur. Bailey & Love's sho practise of surgery,25 th edition,page no:885
Surgery
Cardio thoracic surgery
5e71a731-a5cb-46a7-a451-25783e003bbd
Which of the following is not a common cause of vasculitis in adults?
Giant Cell Aeritis
Polyaeritis nodosa
Kawasaki disease
Churg-Strauss syndrome
2c
single
Kawasaki disease (mucocutaneous lymph node syndrome) is an aeritis that often involves the coronary aeries (large- to medium-sized vessel aeritis), usually in young children and infants (majority of the cases are seen in <5 years old).
Pathology
Vasculitis
63452547-c264-400a-8965-239f1a377431
Which of the following is the BEST indicator of ovarian reserve?
FSH
Estradiol
LH
FSH/LH ratio
0a
single
Measurement of rise in basal FSH is an excellent indicator of ovarian aging. As women age serum FSH concentrations in the early follicular phase begins to increase due to a decline in the number of small follicles secreting inhibin. Day 3 FSH concentration greater than 20 to 25 IU/L is considered to be elevated and is ...
Gynaecology & Obstetrics
null
b4f0b993-6a80-4730-9f7c-44462ef553c6
As per WHO, notifiable disease is
Cholera
Malaria
Dengue
Pneumonia
0a
single
Cholera Cholera is an acute diarrhoea disease caused by Vibrio cholera Vibrio cholera : 'Gram-negative bacterium' that produces cholera toxin (enterotoxin), which act on C-AMP system of mucosal cells of epithelium lining of the small intestine (to cause massive diarrhoea) Classic biotype El Tor biotype (serotypes: Ogaw...
Social & Preventive Medicine
Communicable diseases
8b0dae57-2777-488c-8d29-fbfc21b366df
Sensory nerve supply of pinna is:
Mandibular nerve
Maxillary nerve
Facial nerve
Abducent nerve
0a
single
Auriculotemporal nerve, a branch of mandibular nerve (V3) supplies the external acoustic meatus, external surface of auricle above this, skin of temporal region and TM joint.
Anatomy
null
cf327e20-4b17-4c75-93b4-d3600885832b
The following tendons pass under extensor retinaculum except
EXTENSOR digitorum brevis
Extensor hallucis
Tibialis anterior
Superficial peroneal nerve
3d
multi
RETINACULA:- Around the ankle, the deep fascia is thickened to form bands called retinacula.Front of ankle- superior and inferior extensor retinaculaLateral-superior and inferior peroneal retinacula.Posteromedially- extensor retinacula. Superior extensor retinacula:- Attachments-Medially-lower pa of anterior border of ...
Anatomy
Lower limb
3f9d4886-d8c1-4a90-b5a4-3f83d84336cd
Wernicke&;s encephalopathy in alcohol consumption can be treated with
Pyridoxine
Thiamine
Riboflavin
Niacin
1b
single
Alcohol-Induced Amnestic Disorder: (1) Wernicke's encephalopathy, Confabulation, Ataxia, Ophthalmoplegia (gaze palsy, lateral orbital palsy)horizontal nystagmus tends to reverse rapidly with thiamine supplementation. it can be remebered with a mnemonic GOA G====Global confusion O====ophthalmoplegia A====Ataxia (2) Kors...
Psychiatry
All India exam
d3285acd-aae9-46d7-96ad-0127cd6a3385
Li is best used in -
MDP - Bipolar
MDP - Unipolar
MDP - rapid cycles
Depression
0a
single
Most important indications of lithium are treatment of acute mania and prophylaxis of bipolar mood disorder, i.e. manic - depressive illness.
Psychiatry
null
8c79dfd4-6e97-47b1-9e05-f1218cf46f99
A young butcher cuts his forearm with a knife. Over the next week, he notices swelling, redness, and warmth at the site. Four days later, he presents to the emergency depament with fever, shaking chills and severe lower back pain. Physical examination reveals a temperature of 39.4 C (102.9 F), swelling in his forearm w...
Bacteroides fragilis
Clostridium perfringens
Escherichia coli
Staphylococcus aureus
3d
single
This organism is a gram positive coccus organized into grape-like clusters. It produces a yellow pigment and the positive mannitol salt agar test showed that it could ferment mannitol and had a high salt tolerance. This organism is catalase positive and coagulase positive, two critical tests for the correct identificat...
Microbiology
null
4fc04b16-b433-4177-afbe-d711acf90f0c
Theophylline levels are increased in all, except
Erythromycin
Smoking
Cimetidine
CHF
1b
multi
Ans. is 'b' i.e., Smoking Smoking induces theophylline metabolism and decreases its plasma level.In certain conditions theophylline concentration is increased, so its dose has to be reduced.These conditions are - Age > 60 years CHFPneumonia Liver failureDrugs causing increased concentration of theophyllineErythromycinC...
Pharmacology
Asthma
729cce5d-95f7-4d07-b797-7219ad089f2f
Most common Glycogen storage disorder to be present in adolescents is?
Mc Ardle disease
Cori disease
Andersen disease
Von Gierke disease
0a
single
Mc Ardle disease (Type V GSD) due to muscle phosphorylase deficiency is the most common GSD to present in adolescents & adults.
Pediatrics
Disorders of Carbohydrate Metabolism
a5dd40d3-4e6a-46ba-aa8f-29c9eecd4174
Retinoblastoma is
Autosomal dominant
Autosomal recessive
X - linked recessive
X- linked dominant
0a
single
(Autosomal dominant) (280- Khurana 4th)RETINOBLASTOMA - Most common intraocular tumour of childhood and malignant melanoma of choroid in adults*** Identified as band on the long arm of chromosome 13(13ql4)* Most hereditary cases are multifocal* Inheritance is autosomal dominant and the risk of transmitting the gene mut...
Ophthalmology
Tumors
436357a1-aac3-491e-9ebd-afc39be9da7c
Coronary blood flow to the left ventricle increases during all Except
Early systole
Myocardial hypoxia
Stimulation of sympathetic nerves of the hea
Aerial hypeension
0a
multi
During early systole, coronary blood flow falls as coronary vessels are compressed by the contracting myocardium.A fall in PO2 has a potent vasodilator effect on coronary vessels. Adenosine released from hypoxic myocardium is also a potent vasodilator.Sympathetic stimulation increases the rate and force of contraction;...
Physiology
General physiology
90caf5e9-2cbf-4899-8299-e66953b15780
Treatment of choice for asymptomatic pseudocyst pancreas is?
Marsupialisation
Conservative
Drainage
Cystogastrostomy
1b
single
ANSWER: (B) ConservativeREF: Sabiston 18th ed chapter 56Recent reports have shown that many pseudocysts eventually resolve without complications. Intervention is not mandatory in all cases unless the pseudocysts areSymptomaticEnlargingAssociated with complications.The likelihood that a pseudocyst will resolve spontaneo...
Surgery
Miscellaneous (Pancreas)
249d0064-d3aa-4d68-bd05-c4defaf87d67
Factor which activates prekallikrein -
Factor VIII
Factor II
Factor X
Factor XII
3d
multi
Ans. is 'd' i.e., Factor XIIo Initiation of intrinsic coagulation pathway occurs when factor XII is exposed to negatively charged surfaceo This leads to activation of factor XII to XIIa.o Factor XIIa can then hydrolyze prekallikrein to kallikrein, which in turn activates more XII to XIIa.
Physiology
Blood: Hemostasis and Blood Coagulation
63894812-2c34-4be3-b892-9fca22d92fd6
Which one of the following brain tumors is highly vascular in nature?
Glioblastoma.
Meningiomas.
C P angle epidermoid.
Pituitary adenomas.
1b
single
Ans. B. MeningiomasA number of neoplastic lesions in the head and neck area are hypervascular, most commonly meningiomas and hemangioblastoma intra cranially and Paragangliomas and juvenile nasopharyngeal angio fibromas extra cranially.
Radiology
Nervous System
0fa01198-e176-44f1-a9f0-bab8afac9af4
Preferential expression of same gene depending on parent of origin is referred to as:
Genomic imprinting
Mosaicism
Anticipation
Non-penetrance
0a
single
Genomic imprinting Phenomenon that leads to preferential expression of an allele depending on its, parental origin. Eg : Beckwith Wiedemann syndrome (have two paternal but no maternal copies of chromosome 11). Albright's hereditary osteodystrophy (sho stature, brachydactyly and PTH resistance).
Pathology
Genetics
56d71743-d367-408e-bc30-87b1c2321151
A 35 years old man presenting with acute pancreatitis. Ideal fluid of choice:
Isotonic crystalloid
Hypertonic crystalloid
Hypotonic crystalloid
Vasopressin
0a
multi
Ans. a. Isotonic crystalloidRef: Harrisons Principle of Internal Medicine 19th Ed; Page No-2096Aggressive intravenous fluid resuscitation; is the most important treatment intervention for acute pancreatitis.For rest the pancreas; the patient is made NPO and to control abdominal pain narcotic analgesics given intravenou...
Medicine
Fluid & Electrolyte
af039816-e8b2-4d94-a159-f0a4eeef4e11
In excessive burns, least useful is -
Blood
Dextran
Ringer lactate
Nasogastric intubation
0a
single
We know that Ringer's lactate is the preferred agent during initial 24 hrs. Nasogastric intubation is done to decrease the risk of emesis and possible aspiration (as parlytic ileus develops in a pt. with significant burn) Dextran is a colloid and can be used in 2nd 24 hrs., however albumin is the preferred and most wid...
Surgery
null
31e5ee87-f9df-407d-9d0a-f6d5f142d344
Maximum iron absorption occurs in
Duodenum
Jejunum
Ileum
Caecum
0a
single
Iron is absorbed from upper small intestine mainly duodenum. In diet, iron occurs in two forms, haem iron and inorganic (non-haem) iron. Haem iron is better absorbed than inorganic iron, but the major fraction of diet is inorganic iron. Inorganic iron is mostly in ferric form; needs to be reduced to ferrous form becau...
Physiology
null
e4985e50-f60c-4e78-bc55-d4aa783699ac
Eversion occurs at the following joints -
Subtalar
Tibiotalar
Inferior tibiofibular
Ankle
0a
single
Joints taking part in inversion and eversion of foot. Principal joints- Subtalar, talocalcaneonavicular Accessory joints- calcaneocuboid, talonavicular
Anatomy
null
a36f34e9-872c-410c-88d1-f599dfbcdc98
Which is true about Familial hypocalciuric hypercalcemia?
Inherited as autosomal recessive pattern
Cause is defect in PTH receptor
Clinical symptoms occur in third decade
Treatment is rarely necessary
3d
multi
Familial hypocalciuric hypercalcemia is an autosomal dominant disorder. Hence choice A is wrong. The mutation in PTH receptor is known as Jansen disease. Hence choice B is wrong. The cause is defective calcium sensing by parathyroid gland leading to excess release of PTH and subsequent hypercalcemia. Urinary reabsorpti...
Medicine
Disorders of Parathyroid Gland
6921724b-2cf7-411d-9983-e6ebdc055fea
Contraindication of rota virus vaccine is -
SC1D
Intussusception
Severe allergic raction
All of above
3d
multi
Ans. is 'd' i.e., All of aboveGuide to Contraindications1 and Precautions to Commonly Used VaccinesVaccineContraindicationsPrecautionsHepatitis B (HepB)o Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine componento Moderate or severe acute illness with or without fevero Infant weighing ...
Pediatrics
Viral Infections
ba981367-c6e1-4656-b408-c5a43fc39e8d
Lanugo hair first appears in a fetus at: UP 07
2nd month
3rd month
4th month
5th month
2c
single
Ans. 4th month
Forensic Medicine
null
4403de57-9d26-421f-afd8-30f77e3ed47f
Leydig cells are derived embryologically from
Mesoderm of gonadal ridge
Endoderm of Genital tubercle
Germ cells
None of the above
0a
multi
Ans. is 'a' i.e., Mesoderm of gonadal ridge Testosterone producing cells, called leyding cells, develop from mesoderm of the gonadal ridge and are located between sex cords.They produce testosterone by week 8.
Anatomy
null
771d507e-97de-483d-88e6-41e83c507842
A young female presented with consumption of some substance in the emergency depament. Greenish blue froth was seen coming out of her nostrils and oral cavity. The poisoning is most likely due to which of the following
Arsenic poisoning
Copper poisoning
Mercury poisoning
Lead poisoning
1b
single
Ans. b. Copper poisoning
Forensic Medicine
null
0460b56d-7782-45e5-9c0d-2deef051f633
In SDS-PAGE (Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis) proteins are separated on basis of:
Mass
Charge
Density
None
0a
multi
A i.e. Mass
Biochemistry
null
147c7014-1a91-4c8d-b4bf-ebf9dd65d7d5
Most common cause of diarrhea in children of developing countries is:
EHEC
ETEC
EAEC
EIEC
1b
single
ETEC Most frequent bacterial cause of diarrhea in children of developing countries. Most common cause of traveler's diarrhea. EPEC Cause infantile diarrhea (outbreaks) Rarely sporadic diarrhea in adults.
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
6619c233-c87e-4b2e-852a-2d93b65ab07c
Secondary vesical calculus refers to stones formed due to:
Hypercalciuria
Injury
Infection
Migrating from above
2c
multi
• Most vesical calculi are formed de novo within the bladder, but some initially may have formed within the kidneys as a dissociated Randall plaque or on a sloughed papilla and subsequently may have passed into the bladder, where additional deposition of crystals cause the stone to grow. • Most renal stones that are sm...
Surgery
null
2f358574-f845-4f07-8b9e-047243734a3c
Alpha agonist has all of the following actions except: September 2009
Hypotension
Hypeension
General anesthesia
Nasal decongestant
2c
multi
Ans. C: General Anesthesia Alpha-adrenoceptor agonists bind to alpha-receptors on vascular smooth muscle and induce smooth contraction and vasoconstriction, thus mimicking the effects of sympathetic adrenergic nerve activation to the blood vessels. Vascular smooth muscle has two types of alpha-adrenoceptors: alphal and...
Pharmacology
null
d10447da-eefd-4163-83f2-23f41bc8ea3d
A newborn with respiratory distress with RR 86/ min, nasal flaring, audible grunting, abdomen lagged behind chest respiratory movement, no lower chest or xiphoid retraction. What is silverman's score –
1
3
5
6
2c
single
null
Pediatrics
null
216b722c-01cb-4032-be2e-32fbfdf9beb2
Giant cells seen
Osteoclastoma
Chondroblastoma
Chordoma
Osteitis fibrosa cystisca
0a
single
Giant cell tumors of bone also known as osteoclastomas are relatively common bone tumors, usually benign which are arising from metaphsis and typically extending into epiphysis of the long bones. Young adults of ages 20-40 are more prone to these conditions. In a x ray we can find soap bubble appearance . >aicles > REF...
Pathology
Breast
e9a18738-14c1-4f3d-a9b7-415b497bc915
Enlarged corneal nerves may be seen in all of the following except:
Keratoconus
Herpes simplex keratitis
Leprosy
Neurofibromatosis
1b
multi
Enlarged corneal nerves not seen in Herpes simplex keratitis. Ref:Color Atlas of Ophthalmology: The Quick-Reference Manual for Diagnosis and Treatment By Amar Agarwal, Soosan Jacob, 2009, Page 191
Ophthalmology
null
2ce4678b-321d-43e7-ad3a-432f56d4df11
Coverings of graffian follicle are all EXCEPT:
Theca externa
Theca interna
Germinal cells
Granulosa cells
2c
multi
ANSWER: (C) Germinal cellsREF: Ganong s 22nd ed chapter 23Coverings of the mature or graffian follicle are (From inner to outer)Innermost the Granulosa cellsThe theca internaThe theca externa
Anatomy
Female Sex Glands
57cf409d-f454-4be6-b829-89354b46fb2b
A conceptus material (foetus) was found by police has been brought of 4 cm length and 10 gm weight. What is the age?
2 weeks
4 weeks
5 weeks
8 weeks
3d
single
Age of foetus is calculated by 'Rule of Haase'. The length of the foetus is measured from the crown to the heel in centimetres. During the first five months of pregnancy the square root of the length gives the approximate age of the foetus in months. During the last five months, the length in cm divided by five gives t...
Forensic Medicine
null
a5bf372b-b113-46e2-83a3-fc97c75b23cb
All of the following are true about regional blood flow in pregnancy except :
Uterine blood flow at term is 750 ml/min
Blood flow through skin decreases
Renal blood flow increases by 50%
Pulmonary blood flow increase
1b
multi
REGIONAL DISTRIBUTION OF BLOOD FLOW: Uterine blood flow is increased from 50 mL/min in non-pregnant state to about 750 mL near term. The increase is due to the combined effect of uteroplacental and fetoplacental vasodilatation. The vasodilatation is due to the smooth muscle relaxing effects of progesterone, estrogen, n...
Gynaecology & Obstetrics
General obstetrics
838ebcf5-956a-4205-bbcc-56fa7b96201e
All of the statements about quarantine are true except
It is synonymous with isolation
Absolute quarantine is restriction during the incubation period
Exclusion of children from schools is an example of modified quarantine
Quarantine should not be longer than the longest incubation period
0a
multi
Quarantine is defined as the limitation of freedom of movement of such well persons or domestic animals exposed to communicable disease for a period of time not longer than the longest usual incubation period of the disease in such manner as to prevent effective contact with those not exposed. In contrast to isolation,...
Social & Preventive Medicine
Epidemiology
c864154e-5705-4fb5-99f2-c1ef3b781e32
All of the following are superficial muscles of the back, EXCEPT?
Trapezius
Erector spinae
Latissimus dorsi
Levator scapulae
1b
multi
Trapezius, levator scapulae, rhomboid major, rhomboid minor, and latissimus dorsi constitute the superficial muscles of the back. Erector spinae, splenius, transversospinalis, and suboccipital muscles constitute the deep muscles of the back. Erector spinae muscle:Iliocostalis, longissimus, and the spinalis muscles toge...
Anatomy
null
a99a3307-1c39-4fe5-8990-91d6001c631a
The daily recommended dose of the fluoride for the children below 3 years is
Less or equal to 0.5 mg
0.5 to 0.7 mg
1.0 to 1.5 mg
None of the above
0a
multi
null
Dental
null
c070e0ab-af56-46e8-aea1-2ada53854ac6
ICD - 10 code in XXI includes all except
Lack of exercise
Alcoholism
Poisoning
Unhealthy found
2c
multi
Chapter XXI includes factors influencing health status and contact with health services Ref : Park&;s textbook of preventive and social medicine; 23rd edition - page no 50
Social & Preventive Medicine
Concept of health and disease
48e3bfd0-de65-4387-8426-ae2a954c87c3
In classic Barret's, the length of columnar epithelium in distal oesophagus is
>1cm
>2cm
>3cm
>4cm
2c
single
Classic Barrett's (>= 3cm columnar epithelium);Sho-segment Barrett's (<3 cm of columnar epithelium);Cardia metaplasia (intestinal metaplasia at the oesophagogastric junction without any macroscopic change at endoscopy).The relative risk of cancer rises with increasing length of abnormal mucosa.
Surgery
G.I.T
9456f3e1-6058-4996-80b3-5bce8d22629a
Carcinoma cervix is associated with all except :
Multipay
Herpes simplex virus
Early coitus
Diabetes mellitus
3d
multi
Diabetes mellitus
Gynaecology & Obstetrics
null
a0f2ae1d-1f87-4661-a223-f29df7e0986d
Apheresis platelet donation--true is all except:
A person with below normal platelet count can donate
Person can donate again after 2 days
Person can donate 2 times maximum in a week
Not more than 24 donations can be done in 1 year
0a
multi
Ans. A.A person with below normal platelet count can donateExplanationSpecific Eligibility Criteria for Apheresis Platelet DonorsAge: 18-60 years and Weight- 50 kg (This is not just for platelet donation but also for all blood and blood product donations in India)Donor platelet count must be > 1,50,000/dL (Option a)If ...
Medicine
Blood
df7afaaa-5f9f-426c-91d0-4f5a67962e0e
Color of hemosiderin is?
Black
Brown
Blue
Yellow
1b
single
Ans. (b) Brown(Ref: Robbins 9th/pg 64; 8th/pg 36-38)Hemosiderin is yellowish-brown granular pigment formed from breakdown of Hb in RE cells; composed of ferritin complex.
Pathology
Misc. (R.B.C)
c4e3f0df-f408-41be-8f48-51f894f4b4b8
A perception experienced in the absence of an external stimulus in clear consciousness is:
Delusion
Hallucination
Illusion
Pseudohallucination
1b
multi
Ans. B. Hallucination3 criteria are essential for definition of hallucination:(A) Percept-like experience in the absence of an external stimulus;(B) Percept-like experience that has the full force and impact of a real perception; and(C) Percept-like experience that is unwilled, occurs spontaneously, and cannot be readi...
Psychiatry
Symptoms & Signs
be2037e5-63be-48be-838e-ffabac01370e
Which of the following adverse effects is most likely to occur with sulfonamides ?
Neurologic effects including headache, dizziness, and lethargy
Hematuria
Fanconi's anemia
Skin reactions
3d
single
null
Pharmacology
null
0cd7f23b-1b26-481d-afa7-9a1763e220a9
Therapeutic drug monitoring is used in -
Diuretic
Metformin
Levodopa
Digoxin
3d
single
Ans. is 'd' i.e., Digoxin Therapeutic drug monitoring is particularly useful in following situations -1. Drugs with low safety margin -a) Digoxinb) Anticonvulsantsc) A ntiarryth micsd) Theophyllinee) Aminoglycoside antibioticsf) Lithiumg) Tricyclic antidepressants2. If individual variations are large - Antidepressants,...
Pharmacology
Pharmacodynamics
4d59a8b5-8aa0-4977-b59b-19a504aed7d8
Which of the following is the allosteric activator of carbamoyl phosphate synthase I?
Glutamine
Oxaloacetate
N-acetyl aspaate
N-acetyl glutamate
3d
multi
Carbamoyl phosphate synthase I is the rate-limiting enzyme of the urea cycle Active only in the presence of N-acetylglutamate(NAG), an allosteric activator that enhances the affinity of the synthase for ATP. Arginine is the allosteric activator of NAG synthase.
Biochemistry
Urea cycle
8c91ab4c-1d7c-44c8-a77a-6d12aefacba3
Sistrunk's operation is used ina) Parotid tumourb) Thyroglossal fistulac) Thyroglossal cystd) Branchial fistula
c
bc
abd
cd
1b
single
Thyroglossal Cyst Cystic swelling developed in the remnant of the thyroglossal duct or tract Present in any pa of the thyroglossal tract (extends from foramen caecum to isthmus of thyroid) Common sites Subhyoid (MC) Floor of mouth Region of thyroid cailage Suprahyoid Beneath the foramen caecum Clinical features It is a...
Anatomy
Head and neck
f1c3475f-429c-4697-8f38-ae1ceaf399cc
An old man was brought to OP by his son telling that his father is having habit of washing his hands 'n' number of times and repetition of other daily routines as well. Characteristic of obsession are all, EXCEPT:
Repetitive behavior
Repetitive behavior
Ego dystonic
Compulsion
1b
multi
According to the DSM-IV, obsessive-compulsive disorder (OCD) is characterized by recurrent obsessions or compulsions that are ego-dystonic and time-consuming and that interfere with normal functioning. Compulsions or compulsive behavior may result when patients engage in repetitive behavior in an attempt to reduce anxi...
Psychiatry
null
257a5ee8-b6c6-4920-b23a-ee272608f82c
All are true about selenocystiene EXCEPT:
Considered as 21stAmino acid
Coded by UGA
Occurs in glutathione peroxidase
Made of cysteine and methionine
3d
multi
Selenocysteine is found in approximately 25 human proteins. Enzymes which use selenocysteine at their active sites are known as Selenoproteins e.g. 1. Glutathione peroxidase 2. Thioredoxinreductase 3. Iodothyroninedeiodinase Precursor amino acid for selenocysteine is serine. (not cysteine or methionine) Coded by UGA co...
Biochemistry
Classification and metabolism of amino acids
4d5327e7-6aad-45d7-b0e2-a19e2e2bf87e
All true about airway management in obese patient except:-
Pre oxygenation is preferred in obese patients
Positioning for laryngoscopy is these patients preferred is stacking
Awake intubation is mode of choice in morbidily obese patients
Patient with history of Obstructive Sleep Apnea are candidates for difficult airway
2c
multi
Airway management in obese Excess fatty tissue tends to make access (intubation, tracheostomy) worse than in lean patients. Proper planning and preparation of airway management is essential: Elevation of the patient's upper body, head and neck. Preoxygenation is mandatory in morbidly obese patients and should be follow...
Anaesthesia
Intravenous Anesthetic Agents
a2ce4a6c-644e-41de-beb6-b494b9c41bd0
Tone decay test is done for:
Cochlear deafness
Neural deafness
Middle ear problem
Otosclerosis
1b
single
(b) Neural deafness(Ref. Anirban Biswas, 5th ed. 56)Tone decay is a function of nerve fatigue.If the nerves are fatigued the patient stops hearing a sound given to him continuously before the completion of 1 minute.A tone decay of more than 30dB is suggestive of retrocochlear or neural deafness
ENT
General
86ee4636-cfaf-48e3-8505-b95fa2b951d6
Most common cause of cushings syndrome is
Pituitary adenoma
Adrenal adenoma
Ectopic ACTH
Iatrogenic steroids
3d
single
Most common cause of Cushing's syndrome is prolonged administration of glucocorticoid harmones.
Pediatrics
null
7bb22797-974c-46d5-be36-e8ee6a7d0aba
Which of the following oncogenes is a growth factor?
fos
myc
jun
sis
3d
single
The 'sis' oncogene is a growth factor. The protooncogene 'sis' encodes the ( b chain of) Platelet Derived Growth Factor (PDGF). Ref: Robbin's Illustrated Pathology, 7th Edition, Pages 293, 295; Cancer: Principles and Practice of Oncology, 6th Edition, Page 13
Pathology
null
328226c9-ec59-4957-8300-8f58e08e2c51
The 'heel effect' results
In low intensity X-ray beam on anode side of central ray
In high intensity beam of X-rays towards cathode
Both of them are true
None of the above are true
2c
multi
null
Radiology
null
46326475-f3ed-48a3-b8ac-926420a25eb8
OVAL cells seen in stem cells of-
Skin
Cornea
Liver
Bone
2c
single
oval cells - canal of herring of the liver limbus cells - canal of schlemm (stem cell for the cornea) epidermal stem cell in the skin bone marrow stromal stem cell - fat,cailage,bone ref robbins pathology 9th ed page 28
Pathology
General pathology
14704711-902e-4dd7-8084-7fd940cf59a9
"Magical thinking" is characteristically seen in
Shizophrenia
Obsessive Compulsive Disorder
Schizotypal personality
Anxiety disorder
2c
multi
(C) Schizotypal personality # SCHIZOTYPAL PERSONALITY DISORDER (STPD) is a personality disorder characterized by a need for social isolation, anxiety in social situations, odd behavior and thinking, and often unconventional beliefs.> Characterised by eccentric behaviour, Poor rapport, Odd beliefs or magical thinking, S...
Psychiatry
Miscellaneous
e5e1b67f-1a7e-4d40-afdf-9c844662e438
Creatinine kinase is elevated in MI after
2-4hrs
4-8hrs.
12-24hrs
>24hrs.
0a
single
CK-MB remains a valuable marker of myocardial injury, second only to the cardiac-specific troponins . Total CK activity is not a reliable marker of cardiac injury since various isoforms of CK are also found in brain, myocardium, and skeletal muscle. However, the CK-MB isoform--principally derived from myocardium, but a...
Pathology
Cardiovascular system
87a303df-6a2e-404b-9678-c0e2eaf1beea
Idiopathic nephrotic syndrome is associated with the following except:
Focal Segmental glomerulosclerosis
Minimal Change Disease
Membranoproliferative glomerulonephritis
Mesangioproliferative glomerulonephritis
3d
multi
Ans. D. Mesangioproliferative glomerulonephritis. (Ref. Robbin's Pathology8th/pg. Table 14-2)Membranoproliferative GN (MPGN) is manifested histologically by alterations in the GBM and mesangium and by proliferation of glomerular cells. It accounts for 5% to 10% of cases of idiopathic nephrotic syndrome in children and ...
Pathology
Kidney
7c9cf0b1-4114-40b4-9fce-8410b1e40fcb
True statement regarding follicular cell carcinoma of thyroid:
Hematogenous spread
Commonly multifocal
Readily diagnosed by FNAC
Most common carcinoma of thyroid
0a
multi
(Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 1120-1124) Histological variants of Thyroid Carcinoma
Unknown
null
d0a542e3-5d0f-4a1d-b278-0f8e48afc6e8
Transperitoneal approach to repair genitourinary fistula is used in all situations except
Fistula closer to ureteral orifices.
Con-comitant ureteric and vesicovaginal fistula.
Fistula located proximally in a narrow vagina.
Non-complicated small vesicovaginal fistula.
3d
multi
Transperitoneal approach of repair is preferred in complex large fistulas.
Gynaecology & Obstetrics
null
ebeb0624-478f-4594-9968-da2a78b87a89
Vitamin D
Absorption requires bile pigments
Synthesis is regulated at the reaction catalyzed by 15-hydroxylase
Deficiency on adults leads to rickets
Along with PTH, increases calcium resorption from bone
3d
single
null
Biochemistry
null
625771fb-b4fb-436c-b66a-b24fe8311fd9
A 22 year old man presents with history of bleeding from gums for the last 6 months. On investigation the b was found to be 8.2 gm% TLC 4400/mm, DLC N 64%, L 27%, E 3%, M 6% and platelet count of 20,000 /cu mm. Which one of the following investigation would be most useful in establishing the diagnosis -
Bleeding time and clotting time
Prothrombin time
Partial thromboplastin time
Bone marrow examination
3d
single
null
Medicine
null
790987c0-aba4-41b4-b021-e22743b2b94d
Pheochromocytoma with malignant potential exclusively secretes
Dopamine
Epinephrine
Metanephrine
Norepinephrine
0a
single
null
Surgery
null
ac24c246-0769-45e4-bfea-1b097a2a58ca
All the following statements about lobular carcinoma of breast are true EXCEPT:
Easily detectable in mammography
30% bilateral
Lobectomy is less preferred
Difficult to detect in mammography.
0a
multi
Ans) a (Easily...) Ref: Sabiston 18th ed, 17th ed p890, Robbins 7th ed p 1144Invasive lobular carcinoma (ILC) may be found by mammography, However, ILCdoes not always show up well on a mammogram because of the cells' tendency to grow in a single-file line, rather than form a mass. If mammogram does find invasive lobula...
Surgery
Breast Cancer - Types and Staging