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135
374161ca-5c39-4f79-b5c2-e1a986e6261b
Which of the following feature is not included in Bergmann's Triad?
Disorientation
Cyanosis
Coma
Bradycardia
3d
single
Bergmann triad consists of:- Cerebral--Delirium, confusion, convulsions, disorientation,stupor,coma Cutaneous--Petechial rashes on chest Cardiopulmonary--Dyspnea, tachypnea, tachycardia, cyanosis, Hypoxia, hypoxemia It is seen in Fat embolism syndromme.
Orthopaedics
Lower Limb Traumatology
06b46a13-01ec-481a-b46b-b19b2ca615b1
All of the following are true about sargramustin except
It is a G - CSF analog
It is used in cases of neutropenia
Chronic usage can lead to bone pain
It can also lead to flu like symptoms
0a
multi
It is a GM - CSF analog. Filagastrim & lenogastrim are G - CSF analogs.
Pharmacology
null
5a73b902-aced-4fd5-b17d-7a11be372dfc
The direct retainer of choice when the principle abutment tooth has Lost its periodontal support is:
Embrasure clasp
Ring clasp
Multiple circlet clasp
Onlay clasp
2c
single
null
Dental
null
02ee866e-f217-413c-b514-da37d7c4b82b
Which of the following is the most common type of congenital cataract?
Sutural cataract
Lamellar cataract
Coronary cataract
Embryonic nuclear cataract
1b
single
Lamellar cataract is the most common type of congenital cataract. It occur in a zone of fetal nucleus surrounding the embryonic nucleus. In this type, the main mass of the lens internal and external to the zone of cataract is clear except for small linear opacities like spokes of wheel seen towards the equator. Coronar...
Ophthalmology
null
417b4e5a-d4e7-4c72-8979-f3ff4b603508
Kayser fleisher ring is characteristic of?
Hemosiderosis
Wilson disease
Tyrosinemia
Hereditary cataract
1b
single
KANSWER: (B) Wilson diseaseREF: Khurana 4th ed page 181 & 410, Yanoff 2nd ed page 278"Kayser-Fleischer rings are caused by copper deposits, and are indicative of Wilson's disease, whereas Fleischer rings are caused by iron deposits and are indicative of keratoconus"In Wilson's disease, an autosomal recessive disorder, ...
Ophthalmology
Cornea
64810c55-8ff5-46bd-83b4-475c6a6b9fe0
Short 4th metacarpal is a feature of
Hypothyroidism
Hyperthyroidism
Pseudohypoparathyroidism
Hypoparathyroidism
2c
single
Seen in pseudohypoparathyroidism and Pseudo pseudo hypoparathyroidism.
Radiology
null
7176ed9e-89fa-475c-8853-d0dfad96bde4
In Spondylolisthesis, which of the following is NOT useful investigation?
Anteroposterior X-ray
Lateral view X-ray
CT
MRI
0a
single
(a)-AP view will show changes only in last stages-inverted Napoleon hat sign all other are more important for diagnosis and management. CT and MRI are required in all cases.
Orthopaedics
Spinal Injuries
0d4d4dfe-7061-4678-afab-a43182634a00
Drug used in remodeling of hea in congestive cardiac failure are all EXCEPT -
Beta blocker
ACE inhibitor
Digoxin
Aldosterone antagonist
2c
multi
Ans. is 'c' i.e., Digoxin
Pharmacology
null
f1ed5e63-20f2-40f9-a3f5-c2903277f835
Which statement best describes a functional role for the lateral hemispheres of the cerebellum?
Control and coordinate movements of the axial muscles, as well as the shoulder and hip
Control movements that involve distal limb musculature
Function with the cerebral coex to plan movements
Stimulate motor neurons through their connections to the spinal cord
2c
multi
From a functional point of view, the cerebellum is divided into three pas: 1. Vestibulocerebellum (or flocculonodular lobe) Consist of the nodulus in the vermis and the flanking flocculus in the hemisphere on each side. This lobe is phylogenetically the oldest pa of the cerebellum and has vestibular connections concern...
Physiology
Motor System
d5d836c5-3c1f-4d83-8a59-77f8b151f584
Cough and sputum in COPD are primarily due to changes in
Large airways
Medium airways
Small airways
Lung parenchyma
0a
multi
Large airways- Cigarette smoking often results in mucus gland enlargement and goblet cell hyperplasia, leading to cough and mucus production that define chronic bronchitis, but these abnormalities are not related to airflow limitation.Small airways- The major site of increased resistance in most individuals with COPD i...
Medicine
Respiratory system
d6dd2c57-a2d9-4452-91a3-7685af64a9cc
Enzyme papain is used?
To decrease intestinal gas produced during digestive process
As Anti helminthic
To treat Herpes zoster
To treat infected wounds in nucleus pulposus
0a
single
ANSWER: (A) To decrease intestinal gas produced during digestive processREF: KDT 6th ed page 649, Katzung 12th ed pagePapain It is a proteolytic enzyme obtained from raw papaya. It is used as digestant. Its efficacy after oral ingestion is doubtful
Pharmacology
G.I.T
4a18bff9-ca33-4a12-9f65-07cb1c2b2e10
The intra - abdominal pressure laparoscopy should be set between :
5-8 mm of Hg
10 - 15 mm of Hg
20 - 25 mm of Hg
30 - 35 mm of Hg
1b
single
10 - 15 mm of Hg
Gynaecology & Obstetrics
null
395ccc72-83e6-440f-b334-2bfb5a525e80
A 20-year-old 70kg man is put on fast perioperatively. 100gm of glucose is given per day as 5% dextrose solution. This is to
Meet daily calorie requirement
Meet daily fluid requirement
Sustain cerebral energy metabolism
Sustain anabolic status
2c
single
During starvation, the body is faced with an obligate need to generate glucose to sustain cerebral energy metabolism (100 g of glucose per day). This is achieved in the first 24 hours by mobilising glycogen stores and thereafter by hepatic gluconeogenesis from amino acids, glycerol and lactate. This eventually leads to...
Surgery
General surgery
b5602f91-b787-4230-96f2-dd24701c4d9f
When a drug binds to the receptor and causes action opposite to that of agonist this is called as?
Complete Agonist
Partial Agonist
Inverse agonist
Neutral antagonist
2c
multi
ANSWER: (C) Inverse agonistREF: Goodman and Gillman 11th edition page 14-15, http://en.wikipedia.org/wiki/Inverse_agonistIndirect repeat from June 2008An inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.A neutral antagonist has no ...
Pharmacology
C.N.S
f28f6fdc-78f9-47f6-957e-be40dab8528c
All of the following statements regarding idiopathic edema are true, EXCEPT:
It is due to estrogen mediated sodium retention
It is not related to menstrual cycle
It is associated with an increased water retention in upright position
In some cases ACEI is useful
0a
multi
Idiopathic edema is an ill-defined syndrome characterized by intermittent pitting edema secondary to Na and water retention. There is only very little evidence to prove that sodium retension is occuring under the influence of estrogen. Patients present with swelling of legs, hand, rarely face along with abdominal bloat...
Medicine
null
c2891254-23ca-45a8-ac4d-5cb166365c9a
A major step in the pathogenesis of listeriosis is -
The formation of antigen-antibody complexes with resultant complement activation and tissue damage
The release of hyaluronidase by L. monocytogenes, which contributes to its dissemination from local sites
The antiphagocytic activity of the L. monocytogenes capsule
The survival and multiplication of L'. monocytogenes within mononuclear phagocytes and host epithelial cells
3d
multi
null
Microbiology
null
e3e5778d-1d9a-431b-9b83-93764d8114fa
Calculate the prevalence if incidence is 2 cases per 1,000 population per year and mean duration is 4 years-
8 mases per 1,000 population
2 cases per 1,000 population
0.5 cases per 1,000 population
32 cases per 1,000 population
0a
single
prevalence is calculated as the product of incidence and mean duration of a disease in a community.during a specific period,here it is given as 4 *2 cases per 1000 population. ref:park&;s textbook,ed 22,pg no 67
Social & Preventive Medicine
Epidemiology
2f958b9a-bd99-47a7-a28b-42505398a24c
Hyperacusis is defined as:
Hearing of only loud sound
Normal sounds heard as loud and painful
Completely deaf
Ability to hear in noisy surroundings
1b
single
Sensation of discomfo or pain on exposure to normal sounds. Seen in injury to nerve to stapedius and in case of congenital syphilis (Hennebe sign)
ENT
null
96cb625b-3946-4711-b8e5-f4a2422148dd
Which of the following is teratogenic: March 2011
Folate
Cyanocobalamin
Vitamin A
Vitamin C
2c
single
Ans. C: Vitamin APharmacological doses of vitamin A are teratogenic and in pregnancy the daily dose must not exceed 6000-8000 IU.Synthetic analogues of vitamin A:TretinoinIsotretinoinEtretinateAcetretinTeratogenic drugsDrugs and medications:- Tobacco Caffeine- Drinking alcohol (ethanol) (fetal alcohol spectrum disorder...
Pharmacology
null
345d2f53-53a9-4b2f-ac26-4e0a5d2d3785
In a patient suspected to be diagnosed with Rabies, a sample of corneal smear was taken. Which of the following investigations can be done from the specimen?
RT PCR
Immunofluorescence test
Negri body visualization
Virus isolation
1b
single
Ans. (b) Immunofluorescence test style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">(Ref: )Lab diagnosis of rabies*RT-PCR: detecting the viral nucleic acid especially on biological fluids (saliva, cerebrospinal fluid, tears) and skin biopsy (ante mortem) and brain samples (post mortem)*Se...
Pathology
Central Nervous System
713893ba-01df-4234-93f3-437060ddc282
MAO inhibitors should not be used with:
Pethidine
Pentazocine
Buprenorphine
Morphine
0a
single
Pethidine should be avoided in patients receiving MAO inhibitors, because both these drugs can result in very high levels of serotonin. MAOI inhibits breakdown of serotonin and pethidine inhibits reuptake of serotonin. This result in excess excitation characterized by agiation, delirium, headache, rigidity, hyperpyrexi...
Pharmacology
null
1005c1d4-84e4-4dea-849b-48456604803e
Renal GFR is best measured by
Tc99 DMSA
Tc99 Pyrophosphate scan
Tc99 DTPA
Creatinine clearance
2c
single
C i.e. Tc99 DTPA 99mTcDMSA (gold standard) and 99mTc- GFIA are morphologic agents. Dimercaptosuccinic acid (DMSA) labelled with technetium-99m is most satisfactory tracer for imaging renal anatomyQ (e.g. in renal ectopia and anomalies like horseshoe kidney), differentiating functional renal masses (with radiotracer upt...
Radiology
null
55265e5b-f83a-41f2-bed0-04852d2b56c6
Which cranial nerve carries parasympathetic fibers?
Vagus nerve
Trigeminal nerve
Hypoglossal nerve
Abducent nerve
0a
single
Ans. A. Vagus nerveThe only cranial nerves that transmit parasympathetic fibers are the oculomotor, facial, glossopharyngeal, and vagus nerves.Parasympathetic flow is cranio-sacral flow carried by cranial nerves: 3,7,9,10 and the sacral nerves: S-2,3,4. These nerves carry the preganglionic fibres to their respective ga...
Anatomy
Head & Neck
adc76304-e1de-4ca8-b2cb-da60c8375fdd
A 27-year-old man presents with chest pain and feeling unwell. He describes cough with blood-tinged sputum, chills, and fever of 2 days' duration. Physical findings reveal dullness and moist rales in the left lower chest. His CXR is shown in Figure given below. Which of the following is the most likely diagnosis?
pneumonia, left lower lobe
atelectasis, left lower lobe
PE
tuberculosis
0a
single
The diagnosis is pneumonia. There is consolidation of the left lower lobe. The increased density, presence of air bronchogram, and the silhouetting of the left diaphragm point to a parenchymal lesion. Pneumococcal infection, as in this patient, is still the most common etiology, although other bacterial infections such...
Medicine
Respiratory
865c98a6-86fa-4e67-9a35-8a316363d7b8
In malignant hyperthermia the increased heat production is due to :
Increased muscle metabolism by excess of calcium ions
Thermic effect of food
Increased sympathetic discharge
Mitochondrial thermogenesis
0a
single
Ans. is 'a' i.e. increased muscle metabolism by excess of calcium ionsRef Harrison 16th/e p 105 (15th/e page 92)Malignant hyperthermiais caused by inherited abnormality in sarcoplasmic reticulum of skeletal muscleDue to this there is rapid increase in intracellular calcium levels in response to certain drugs.This leads...
Pathology
Endocrine
e325dab2-1ab5-4b17-adb6-c8db2c66d1fd
In exocrine pancreatic, cancer, the commonest tumor marker to be elevated in
CA 125
CEA
CA 15-3
CA 19-9
3d
single
.Investigations for exocrine pancreatic tumors includes * Liver function tests: Serum bilirubin, direct component (conjugated) is increased (van den Bergh's test). Serum albumin is decreased with altered A : G ratio. Prothrombin time is widened. Serum alkaline phosphatase is increased * U/S abdomen to see gall bladder,...
Surgery
G.I.T
8a21c581-a417-45e4-ac23-62d6377082d3
Most common complication of cardiac catheterization?
Arrhythmia
Hypeension
Vascular bleeding
Contrast reaction
2c
single
the most common complication of cardiac catherisation is vascular bleeding or hematoma formation Risks of cardiac catheterization are: Bruising. Bleeding.(vascular bleeding) Hea attack. Stroke. Damage to the aery, hea or the area where the catheter was inseed. Irregular hea rhythms (arrhythmias) Allergic reactions to t...
Medicine
C.V.S
9d92e126-5721-43ad-9b1c-eb8fe2dbc290
In a healthy subject, when is the PO2 of the blood leaving a pulmonary capillary lower than the PO2 in the alveolus served by that capillary?
While breathing a low O2 gas mixture
While performing an exercise in which the cardiac output doubles
At the base of the lungs, where perfusion exceeds ventilation
None of the above
3d
multi
Blood spends about 0.75 sec in a pulmonary capillary; and under normal conditions, all of the gas exchange in the vessel occurs early. Because equilibrium is reached so rapidly (less than 0.25 sec for both O2 and CO2), blood at the end of a pulmonary capillary has the same P02 and PCO2 as alveolar gas, and gas ex­chang...
Unknown
null
2623318a-686d-4a3c-910e-a0b98ca919a6
Mid-diastolic Murmur with presystolic accentuation is typically seen in
Mitral stenosis
Mitral Regurgitation
Aoic stenosis
MVP
0a
multi
An opening snap, mid-diastolic rumbling murmur, presystolic accentuation and loud first hea sound are all characteristic of mitral stenosis.The mid-diastolic rumble (murmur) stas with the opening snap and may extend to the S1 with presystolic accentuation.Ref: Harrison's 18/e. p1930, 1931.
Medicine
All India exam
7f5bed0c-f1d8-4f77-b27f-e1baac4e2e4f
Leukocyte alkaline phosphatase is elevated in:
Pernicious anemia
Sickle cell anemia
Polycythemia vera
Plummer Vinson syndrome
2c
single
null
Medicine
null
b6753cfc-22be-4e74-8ed6-d29f4ec3b24d
Sinus tachycardia is seen in
Beta blocker therapy
Athletes
Hypothyroidism
Severe anaemia
3d
single
null
Medicine
null
7e0d39b1-8388-480b-87f3-017d5d427558
Mucous glands are absent in
Cervix
Esophagus
Vagina
Duodenum
2c
single
INDERBIR SINGH&;S TEXTBOOK OF HUMAN HISTOLOGY-PAGE NO:359 Vagina Mucous membrane The epithelium rests on dense connective tissue that is highly vascular,many veins being present .the tissue is rich in elastic fibres.no glands are seen in the mucosa,the vaginal surface being kept moist by the secretions if glands in the...
Anatomy
General anatomy
39c8828a-58a1-496c-91d3-6de6a0a81d1e
Blood transfusion is indicated in following condition with sickle cell anemia
Frequent sickling episodes
Twin pregnancy
Poor obstetrical outcome
All of the above
3d
multi
Indications of Blood transfusion in Sickle Cell Anemia Frequent sickling episodes Twin pregnancy Poor obstetrical outcome Severe anemia Blood transfusion replaces the abnormal cells with normal red cells The objective of transfusion is to keep the hematocrit value above 25% and concentration of Hb-S under 50% Prophylac...
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
a803cd1c-910e-4d42-8535-bc247656adb2
Shentons line is seen in X ray of -
Antero-posterior pelvis with both hips
Antero-posterior shoulder
Lateral cervical spine
Lateral lumbosacral spine
0a
multi
Ans. is 'a' i.e, Antero-posterior pelvis with both hips Plain X - ray for hip pathology:* The minimum required is an anteroposterior x-ray of the pelvis showing both hips and a lateral view of each hip separately.* The two sides can be compared: any difference in the size, shape or position of the femoral heads is impo...
Orthopaedics
Injuries Around Hip
b362cadb-72b6-4319-8cd3-3db39d25b8ed
During normal conversation, sound heard at 1meter distance is
60dB
80dB
90dB
120dB
0a
single
At a distance of 1 m, intensity of Whisper = 30 dB Normal conversation = 60 dB Shout = 90 dB Discomfo of the ear = 120 dB Pain in the ear = 130 dB Ref: Dhingra 7e pg 21.
ENT
Ear
ad812a73-612a-4a76-8d55-fb5f91dd6227
The etiology of anterior ethmoidal neuralgia is:
Inferior turbinate pressing on the nasal septum
Middle turbinate pressing on the nasal septum
Superior turbinate pressing on the nasal septum
Causing obstruction of sphenoid opening
1b
single
Sluder's neuralgia or the anterior ethmoidal syndrome is pain around the bridge of the nose radiating into the forehead. It is said to originate from the middle turbinate (pa of ethmoid bone) pressing on the deted septum. This is a rare cause of headache and also k/a contact point headache.
ENT
null
986e04c1-a818-4680-b48c-2bca043c7417
Most suggestive of anti moem hanging ?
Salivary dribbling
Congestion of lungs
Ligature marks
Petechial hemorrhages
0a
single
Most suggestive of antemoem hanging is Salivary dribbling . There is no specific gold standard to distinguish between antemoem and postmoem hanging.However presence of : Veical salivary dribble mark from the dependant angle of mouth. The phenomenon of Le Facies sympathique. Hyperemia and echymosis of margins of ligatur...
Forensic Medicine
Hanging and strangulation
02e15cf9-0ca7-47a9-8269-fc557e11ef2d
All of the following are radio-opaque stones except: September 2009
Calcium
Struvite
Uric acid
Cystine
2c
multi
Ans. C: Uric acid
Surgery
null
bfad0536-1c5d-4dde-ad97-d85ddfccc861
In CA stomach, T4 lesion means
Involved till serosa
Involved till lamnia propria
Involved till submucosa
Involved till muscularis propria
0a
single
T1a Tumour involves lamina propria T1b Tumour involvessubmucosaT2 Tumour invades muscularis propriaT3 Tumour involves subserosa T4a Tumour perforates serosaT4b Tumour invades adjacent organsBailey and love 27e pg: 1135
Surgery
G.I.T
7ed43862-2edd-4b5c-bbcc-69dd95d770f3
A young patient presents to the ophthalmology clinic with loss of central vision. ERG is normal but EOG is abnormal. Which of the following is the most likely diagnosis -
Stargardt's disease
Best's Vitelliform Dystrophy
Retinitis Pigmentosa
Cone- Rod Dystrophy
1b
single
Normal ERG with an abnormal EOG is charachteristic of best's vittelliform dystrophy.
Ophthalmology
null
dcada2c3-3282-43ec-9848-b36d9114e46d
preservative used for this suture material?
saline
ethanol
formalin
isopropyl alcohol
3d
single
Catgut suture are available in the form of plain catgut or chromic catgut preservative used is ISOPROPYL ALCOHOL life span for plain catgut is 10-14 days chromic catgut is -40-60days Plain catgut is usually having shoer absorption periods and is absorbed more rapidly in infected areas. The percentage of collagen in the...
Surgery
All India exam
a66ffca3-43ba-46ed-af2f-9a397610ba9c
Following are TVS findings of Adenomyosis except
Transition zone > 12mm thick
Endometrial cyst
Heterogenous myometrium
Subendometrial striations.
1b
multi
Adenomyosis is characterised by myometrial cyst, which is most specific sign.
Gynaecology & Obstetrics
null
b5a410d5-95cb-4aa0-9147-04b99c82af82
Preganglionic Parasympathetic fibres are not carried by which cranial nerve -
III
V
VII
X
1b
single
Ans. is 'b' i.e., V o Parasympathetic origin ---> Cranio-Sacral (III, VII, IX, X, S2-S4) o Sympathetic origin --> Dorso-lumbar (T1 to L2 or L3)
Pharmacology
null
3ba454af-1ffc-4b0e-a5b1-d4c0bf84c719
The drug of choice for chemoprophylaxis in contacts of a patient of pneumonic plague is -
Penicillin.
Rifampicin
Erythromycin
Tetracycline
3d
single
null
Microbiology
null
29115237-8465-4cf3-9133-b2c13acd2098
Pontiac fever is caused by -
Legionella
Listeria
Scrub typhus
Leptospira
0a
single
null
Microbiology
null
c1acb3d2-9b77-46c4-a62b-aae373baa64f
In glycolysis, the conversion of 1 mol of fructose 1,6-bisphosphate to 2 mol of pyruvate results in the formation of:
1 mol NAD+ and 2 mol of ATP
2 mol NAD+ and 4 mol of ATP
2 mol NADH and 2 mol of ATP
2 mol NADH and 4 mol of ATP
3d
single
null
Biochemistry
null
a7b5bb4c-2c92-4610-90a6-2b3eadf69ce1
A previously healthy 30-year-old man has been unable to open his right eye.Which of the following cranial nerves is most likely to be affected?
3
4
6
7
0a
single
Opening of the eye is related to Levator Palpebrae Superioris - IIIrd nerve affected so L.P.S will not be able to function Leading to PTOSIS
Medicine
Intracranial Space Occupying Lesion
a34f9a36-3a4c-4b41-8710-12189cc82632
Best tumor marker for pancreatic cancer?
CA 125
CA 19-9
CEA
AFP
1b
single
Ans. B. CA 19-9. (Ref. H - 17th / pg. 483)Best tumor marker for pancreatic cancer is CA 19-9.CA 19-9 as a Marker for Pancreatic Cancer# CA 19-9 is not recommended for use as a screening test for pancreatic cancer. The use of CA19-9 testing alone is not recommended for use in determining operability or the results of op...
Medicine
Oncology
8c964ed5-4c02-4703-9be0-4292637448e0
A 76-year-old woman presents to the office for evaluation of symptoms of weight loss, anxiety, and palpitations. The symptoms started 1 month ago, and are involuntary. She has no prior history of anxiety or palpitations and her only medical history is hypertension for which she is taking losartan.On examination, the bl...
prolonged circulation time
decreased cardiac output
paroxysmal atrial fibrillation
pericardial effusion
2c
single
Atrial fibrillation is particularly common in older individuals with hyperthyroidism. Thyroid disease may affect the heart muscle directly or there may be excessive sympathetic stimulation. Common symptoms of thyrotoxic heart disease include palpitations, exertional dyspnea, and worsening angina. Pericardial effusion, ...
Medicine
C.V.S.
09fbd0db-cffe-4e2c-a3c9-3282c7ca1440
Anatomic characteristics of the spleen include?
Blood supply to the spleen includes branches from the left renal aery
The spleen is wholly contained within the lesser sac
The spleen lies in the retroperitoneal space
The splenic aery is a terminal branch of the celiac trunk
3d
single
The aerial supply to the spleen is derived from the splenic aery, which arises within the hepatic aery as the terminal branches of the celiac trunk. The spleen is located with in the dorsal mesentery of the stomach protruding in pa into the omental bursa. The blood vessels enter the spleen in the splenic pedicle, the m...
Anatomy
null
27d259dc-3353-421f-9e4d-620d05c8a72f
During extractions of maxillary second molar a 0.5mm perforation is created in maxillary sinus. The appropriate treatment would be to:
Perform cald well-Luc procedure
Smoothen the bone and place suture across socket
Pack the opening with iodoform gauge and allow to heal by secondary intention
No treatment necessary
3d
multi
null
Surgery
null
db7fb0c1-eed3-45c7-b1a0-9842bf346bd5
Which of the following amino acid is both polar and ionic?
Arginine
Asparagine
Glutamine
Leucine
0a
multi
4 Classification of amino acids Polarity & Solubility Hydrophobic amino acid Tryptophan , Tyrosine , Methionine , Leucine , Valine , Isoleucine , Alanine , Phenylalanine , Proline , Glycine Hydrophilic amino acid Neutral amino acid Threonine , Serine , Tyrosine , Cysteine , Asparagine , Glutamine Acidic amino acid Aspa...
Anatomy
All India exam
3bea1c5c-7bf0-43bf-883d-a50ac6116951
A 26-year-old female presents for ante natal visit. She has a history of aboion in last pregnancy due to neural tube defect in the fetus. What is the amount of folic acid that should be prescribed to this female?
4 micrograms per day
40 micrograms per day
400 micrograms per day
4000 micrograms per day
3d
single
*All women of childbearing age and who are capable of becoming pregnant should take 0.4mg (=400mcg) of folic acid daily. *If pregnancy is planned in high-risk women(previously affected child), supplementation should be staed with 4mg (=4000microgram) of folic acid daily, beginning 1 month before the time of the planned...
Pharmacology
Central Nervous system
0cb08b79-3782-4979-b1f3-86c8d2205132
The serine proteases are all except
Elastase
Chymotrypsin
Trypsin
Pepsin
3d
multi
They are enzymes with a serine residue at the active site and most of the proteolytic enzymes belong to this group, e.g. trypsin, chymotrypsin, clotting factors. Ref: DM Vasudevan, page no: 44
Biochemistry
nutrition and digestion
af2a31fe-26c1-42c4-81ff-8181729e517a
All are true about the Sympathetic vasodilator system except
It originates from the frontal coex
It has a strong basal tone
The fibres to skeletal muscles are cholinergic
After sympathectomy, the blood vessels dilate
1b
multi
There is no tonic activity in the vasodilator fibers(sympathetic), but the vasoconstrictor fibers to most vascular beds have some tonic activity Sympathetic noradrenergic fibers end on blood vessels in all pas of the body to mediate vasoconstriction- So sympathectomy cause vasodilation Resistance vessels in skeletal mu...
Physiology
Cardiovascular system
6e9666fc-6869-40f5-9db9-493c35450c0c
Exploratory laparoscopy was performed on a 34-year-old male, following a successful emergency appendectomy. Which of the following anatomic relationships would be seen clearly, without dissection, when the surgeon exposes the beginning of the jejunum?
The second portion of the duodenum is related anteriorly to the hilum of the right kidney.
The superior mesenteric artery and vein pass posterior to the third part of the duodenum.
The portal vein crosses anterior to the neck of the pancreas.
The second part of the duodenum is crossed anteriorly by the attachment of the transverse mesocolon.
3d
single
The second part of the duodenum is crossed anteriorly by the transverse mesocolon, a relationship that can be seen when the beginning of the jejunum is exposed by lifting the transverse colon superiorly. The posterior relationships of the second part of the duodenum and the portal vein cannot be seen without some disse...
Anatomy
Abdomen & Pelvis
df552a3d-f426-4684-92ec-44931c38973a
Enterocele formation is a common complication of
Suburethral sling surgery
TVT
Burch colposuspension
TOT
2c
single
BURCH COLPOSUSPENSION COMPLICATIONS Hemorrhage during dissection of the space Urethra and bladder neck injury due to injudicious placement of sutures Osteitis pubis voiding difficulty detrusor instability Enterocele formation Failure and recurrence D.C.DUTTA&;S TEXTBOOK OF GYNAECOLOGY,Pg no:404,6th edition
Gynaecology & Obstetrics
Urogynecology
9081ca20-ab9a-47b2-8c68-f5b715677429
The most constant early symptom of uterine rupture during labour is :
Shock
Pain
Vaginal bleeding
Cessation of labour
1b
single
Pain
Gynaecology & Obstetrics
null
23beed0a-aec0-41e6-b8da-683801cb01d9
All of the following factor stimulate angiogenesis in a fetus Except:
Vascular Endothelial Growth Factor (VEGF)
Basic Fibroblast Growth Factor (bFGF)
Interleukin - 8 (IL8)
Interferon Alpha (INFa)
3d
multi
D i.e. Interferon Alpha (INFa) 'Ocular Angiogenesis' by Tombran - Tink and Barnstable (2006)/297; Lasers in Ophthalmology (2003)/ 2251 Interferon alpha is an anti- angiogenic' agent that suppresses angiogenesis. 'Interferon alpha is an anti- angiogenic agent. Interferon alpha 2a causes dramatic involution of hemangioma...
Ophthalmology
null
77a5df11-139c-4077-b102-aea20f2b561a
In a patient with renal cell carcinoma with a thrombus in IVC renal vein, which is the best investigation for diagnosis?
CT scan
Angiography
Colour doppler imaging
IVP
0a
single
Investigation of choice in RCC-CT scan. REF : DAVID SUTTON 7th ed
Radiology
null
7a194632-0eb6-46b2-9df0-a0859b957cff
Chronically lymphoedematous limb ispredisposed to all of the following except -
Thickening of the skin
Recurrent soft tissue infections
Marjolin's ulcer
Sarcoma
2c
multi
null
Surgery
null
5e4773af-58ec-499b-a7dd-05706db54de0
What is implied, if a drug has more renal clearance than the GFR
Drug is reabsorbed in the tubules
Drug is secreted in the tubules
Drug is excreted in bile
Drug is neither secreted, nor reabsorbed
1b
single
If clearance of a substance is greater than GFR, then tubular secretion must be present.
Physiology
null
f7979a38-a308-4bb3-bbc7-56463f9f5ed8
QT prolongation is seen in all, except:
Hypothermia
Digitalis toxicity
Hypocalcemia
Romanowand syndrome
1b
multi
Answer is B (Digitalis toxity) QT interval is shoened in digitalis toxity and not prolonged QT interval Is measured from the beginning of Q wave to the end of T wave Q It is the time taken for total ventricular events i.e. depolarization as well as repolarization 2 Normal QT interval should not exceed 42 seconds
Medicine
null
cac221d5-4ef8-4322-8572-85d3c6e02608
The surface marking of the arch of aorta is as follows -
Behind the manubrium sterni
2nd intercostal space
3rd intercostal space
Left 2nd costal cartilage
0a
single
Arch of Aorta surface marking Right end of sternal angle Centre of manubrium sterni Sternal end of left second costal cartilage These points when connected lies behind the lower half of manubrium sterni.
Anatomy
null
e034059f-7d45-4d68-bca5-82cb95f416d9
Malaria protection comes from all Except
G6PD deficiency
Thalassemia
Sickle cell anemia
Acanthocytosis
3d
multi
The geographic distributions of sickle cell disease, hemoglobins C and E, hereditary ovalocytosis, the thalassemias, and glucose-6-phosphate dehydrogenase (G6PD) deficiency closely resemble that of falciparum malaria before the introduction of control measures.This similarity suggests that these genetic disorders confe...
Medicine
C.V.S
967dfea1-5672-4837-a9a3-14f839b4d193
Which is not a product of Pentose phosphate pathway
Glyceraldehyde 3 PO4
NADPH
Sedoheptulose PO4
CO2
3d
single
null
Biochemistry
null
4239b12d-d81d-4fa6-9954-f927f5aaef02
Which enzyme Deficiency leads to serious side effects with 5FU
CYPD29
Dihydropyrimidine dehydrogenase
Uridine di phosphate
Purine
1b
single
Ans. b. Dihydropyrimidine dehydrogenaseRef: Goodman Gilman 13th E/P 11825FU is metabolized by Dihydropyrimidine dehydrogenase in liver and other tissues including tumor cells.Deficiency of this enzyme in patients can lead to a decreased metabolism and increased toxicity of 5FU like severe diarrhea and shock leading to ...
Pharmacology
Anti-Cancer
0d41f8ef-4dfa-44e0-990f-8abbb09de804
TRH stimulation testing is useful in diagnosis of disorders of following hormones?
PTH
Insulin
ACTH
Growth hormone
3d
single
Thyrotropin releasing hormone stimulates the release of TSH, GH and prolactin. Patients with acromegaly shows a rise in serum growth hormone levels following an injection of TRH. TRH stimulation test is also used to monitor the therapeutic response of patients with acromegaly to trans sphenoidal surgery, pituitary radi...
Physiology
null
566c1b9c-344b-478e-80eb-3e2103ad0f2a
Effect of environment on genes is called?
Positive Eugenics
Negative Eugenics
Euthenics
Enthenics
2c
multi
Ans. is 'c' i.e., Euthenics Eugenics Science which aims to improve the genetic endoment of human population. o That is improving the quality of the human species or a human population by genetic manipulation. o Eugenis may be : 1. Negative Discouraging reproduction by persons having genetic defect or presumed to have i...
Social & Preventive Medicine
null
ce6eb330-bf18-4218-a87b-3ad9db5fb840
Screening age for trachoma is:
Below 5 years school child only
1-9 years
9-14 years
5-15 years
1b
single
Ans. b. 1-9 years (Ref: Trachoma Surveillance Annual Report 2008; Park 23/e p308)Screening age for trachoma is 1-9 years.School children are screened and mass treatment with azithromycin is given in areas found to have active trachoma (TF >10% in children aged 1-9 years).Trachoma control includes all the components of ...
Social & Preventive Medicine
Health Programmes in India
d25d9dd4-d39a-4aab-b6cd-d0af2803c032
Inventory of material means which one of the following -
List of items procured
Stock distributed during a period
The quantum of material ordered for
Stock on hand at any given time
3d
single
Inventory management is a discipline primarily about specifying the shape and placement of stocked goods. It is required at different locations within a facility or within many locations of a supply network to precede the regular and planned course of production and stock of materials. The concept of inventory, stock o...
Social & Preventive Medicine
Social science, Mental health & Genetics
21e4dc0f-c463-4627-bde7-eabdb622a139
All are the histological features of Pulmonary hypeension -
Capillaritis of alveolar septa
Saddle thrombi in pulmonary trunk
Thrombi in pulmonary vasculature
All
2c
multi
Ans. is 'c' i.e., Thrombi in pulmonary vasculature Pulmonary Hypeension o In pulmonary hypeension pathological changes are seen from main pulmonary aeries to aerioles. They are : (a) Aerioles and small pulmonary aeries : (i) Medial hyperophy (ii) Thickening and reduplication of elastic lamina. (iii) Plexiform pulmonary...
Pathology
null
f9711229-c919-4ec7-a9cd-b0016b124e7d
First secondary ossification center appears in
Lower end of femur
Upper end of humerus
Lower end of fibula
Upper end of tibia
0a
single
Ans. is 'a' i.e., Lower end of femur Site given in question Secondary ossification center appears at Lower end of femur 9th month intrauterine life Upper end of tibia At bih Upper end humerus 1/2 -1 year of age Lower end of fibula 1 year of age
Forensic Medicine
null
704d2de8-9fb4-4e4a-b000-1e5287538ee8
DNA covering material in a virus is called as?
Capsomere
Capsid
Nucleocapsid
Envelope
1b
multi
Ans. is 'b' i.e., Capsid Structure of virus . The extracellular infectious virus paicle is called as the virion. . The virion consist of a nucleic acid surrounded by a protein coat, the capsid. . The capsid with the enclosed nucleic acid is known as the nucleocapsid. . Two kinds of symmetry are encountered in the capsi...
Microbiology
null
16dd4a48-468f-41d5-ae67-e617474a4e50
Tide water mark dermatitis is seen:-
Allergic contact dermatitis
Contact dermatitis to rubber used in disposable napkins
Band shaped papular dermatitis
Papulo-erosive ulcer
2c
multi
Tide water mark dermatitis is a band shaped papular eruptions on the thighs and abdomen at the diaper edges, characteristically sparing the skin folds Variant of contact dermatitis.
Dental
JIPMER 2018
643bbc5d-534e-46a3-bc64-85ffb7ff00d6
All the following can be used to predict severe acute pancreatitis except NOT RELATED MEDICINE
Glasgow score > 3
CT severity score > 7
APACHE-II score >8
Serum lipase >5 times the normal
3d
multi
.
Pharmacology
All India exam
81da4bf8-9804-4b4a-95bf-e241a8fefed8
All of the following procedures are recommended in dark room processing except:
Use of high intensity and short wavelength light (Red)
Light is placed 4 feet above the processing tank
Light is placed behind the processing tank
X-ray of red filter GBX-2 is used
0a
multi
One of the most important requirements is that the darkroom be lightproof. If it is not, stray light can cause film fogging and loss of contrast. To make the darkroom lightproof, a light-tight door or doorless maze (if space permits) is used. SAFELIGHTING The processing room should have both white illumination and safe...
Radiology
null
a1668df3-ad2a-4591-8d36-d3db9a07eb7f
In tumor lysis syndrome all of the following are seen except -
Hypernatremia
Hypercalcemia
Hyperkalemia
Hyperphosphatemia
1b
multi
Tumor lysis syndrome Caused by destruction of large number of rapidly proliferating neoplastic cells. It frequently leads to ARF It is characterized by Hypocalcemia  Hyperkalemia    Lactic acidosis    Hyperuricemia Hyperphosphatemia                            Most frequently associated with treatment of Burkitt lymp...
Pathology
null
69154946-1a1f-4593-a3aa-2a8fb92ad21f
Renal pa of inferior vana cava develops from?
Vitelline vein
Subcardinal vein
Supracardinal vein
Common cardinal vein
1b
single
null
Anatomy
General anatomy
40752e15-b244-47b8-a485-485596104dfb
There is an increased risk of what in pregnant women with thyroid peroxidase antibodies
Pre-term delivery
Abruptio placenta
Preterm rupture of membrane
Placenta previa
1b
single
In women with TPO antibodies, there is high risk for placental abruption.
Gynaecology & Obstetrics
null
189dadb3-4625-4636-98ac-e725439bcd82
Following is a non-essential amino acid:
Phenylalanine
Proline
Tryptophan
Threonine
1b
single
null
Biochemistry
null
8c730cd3-25c6-4f1a-8427-3eb663d6dbe0
About Retinitis pigmentosa all are true EXCEPT:
Night blindness
Waxy disc
Early loss of central vision
Attenuation of retinal vessels
2c
multi
ANSWER: (C) Early loss of central visionREF: khurana 4th ed p. 260-262Retinitis pigmentosaNight blindness is earliest featureDefective dark adaptationPartial or ring scotomaTubular visionLoss of central vision by age of 50-60 yearsFundus changesRetinal pigmentary changes typically perivascular and resemble bone corpusc...
Ophthalmology
Dystrophies and Degenerations
27ff71d6-352d-47d1-adc4-6628d71fefb6
True about metastatic calcification is
Calcium level is normal
Occurs in dead and dying tissue
Occurs in damaged hea valve
Mitochondria involved earliest
3d
multi
Ref, Robbins 8/e p38;7/e p41-42,9/e p65
Anatomy
General anatomy
5550a0fa-86fe-4d45-a280-2c937465b804
State with highest prevalence of blindness
Jammu - kashmir
Maharashtra
Bihar
Uttaranchal
0a
single
null
Social & Preventive Medicine
null
ba9cf44b-c9c0-4db1-8853-b59798edb60f
Most common surgical cause of obstructive jaundice
Periampullary carcinoma
Carcinoma gallbladder
Carcinoma head of pancreas
CBD stones
3d
multi
Clinical features suspicious of biliary obstruction due to CBD stones include biliary colic, jaundice, clay coloured stools and darkening of urine It is treated by ERCP, laparoscopic or open exploration CBD stones are seen in 6-12% of patients with GB stones Incidence becomes high and surgery is the treatment of choice...
Anatomy
G.I.T
6129d5d7-dfeb-4265-847d-9cc2e71393c7
Which of the following is given to treat thrombocytopenia secondary to anti-cancer therapy and is known to stimulate progenitor megakaryocytes
Filgrastim
Oprelvekin
Erythropoietin
Anagrelide
1b
single
Ans. is 'b' i.e., Oprelvekin
Medicine
null
3b2d2bc3-4907-4e66-837a-0a02b6a0492b
Concurrent flexion of both wrists in response to electrical stimulation is characteristic of which area of the nervous system?
Postcentral gyrus
Vestibulospinal tract
Dentate nucleus
Supplementary motor coex
3d
multi
The supplementary motor area tends to produce bilateral motor responses when stimulated. The other areas would tend to produce unilateral responses.
Physiology
All India exam
c5e85b2d-3fc2-4c25-b6ea-42a0ca123305
According to the treatment plan plaque control, root planning under:
Preliminary phase.
Etiotropic phase.
Surgical phase.
Restorative phase.
1b
single
Phase 1 is also known as Etiotropic phase which includes plaque control, diet control, scaling, root planning and temporary restorations.
Dental
null
f9abc852-7d7a-43f0-9bc9-ea6f3606b887
A new born with respiratory distress with RR 86/min, nasal flaring, audible grunting, abdomen lagged behind chest respiratory movement, no lower chest or xiphoid retraction. What is silverman&;s score
1
3
5
6
2c
single
Silverman Anderson Score (SAS) are widely used for the categorization of respiratory distress in neonates. It consists of five items: (1) chest retraction as compared with abdominal retraction during inhalation; (2) retraction of the lower intercostal muscles; (3) xiphoid retraction; (4) flaring of the nares with inhal...
Pediatrics
New born infants
61552325-a36b-4b99-8745-f7376e7ae9ab
Dense zone of calcification at growing metaphysis seen in scurvy is ___:
Wimberger's ring sign
Pelkan spur
Frankel's line
Trummerfeld zone
2c
single
Ans. C. Frankel's line* Scurvy is due to the deposition of defective collagen in the bone.* Radiological features of scurvy:- Zone of provisional calcification at the growing metaphysis is dense, giving a white line called as Frankel's line,- Sclerotic rim around the epiphysis known as Wimberger's ring sign.- Area of l...
Radiology
Skeletal System
73c9e1d1-7158-4f5e-9f08-48904d42ab38
Disecting hematoma is a clinical complication occurring in
Turner's syndrome
Klinefelter's syndrome
Down syndrome
Marfan syndrome
3d
single
Marfan Syndrome Marfan syndrome is a disorder of connective tissues, manifested principally by changes in the skeleton, eyes, and cardiovascular system. Its prevalence is estimated to be 1 in 5000. Approximately 70% to 85% of cases are familial and transmitted by autosomal dominant inheritance. The remainder are sporad...
Medicine
Genetics
2e3e231e-a655-4a04-9fc1-5aafaeb468e1
Colonic pseudo-obstruction occurs in all, except:
Diabetes mellitus
Dermatomyositis
Scleroderma
Hyperthyroidism
3d
multi
Ans. (d) HyperthyroidismCauses of secondary pseudo-obstruction of colon: (Secondary pseudo-obstruction of colon is most common)* Neurological medications* Opiates* Myxedema (Hypothyroidism)* Hyper parathyroidism* Uremia* SLE* Scleroderma* Diabetes mellitus* Retroperitoneal hematoma* Parkinson's disease* Metabolic disea...
Surgery
Small & Large Intestine
9c7d6822-548b-4999-b551-07dea90b8062
The commonest presenting complaint In a gynaecology depament is :
Bleeding PV
Leucorrhoea
Prolapse uterus
Mass abdomen
1b
single
Leucorrhoea
Gynaecology & Obstetrics
null
1e144dd1-32c7-45d2-bde9-3567ec2cfdbb
The management technique which is more promising tool for application in health field is:-
Cost effective analysis
Cost benefit analysis
Cost accounting
Input output analysis
0a
single
Cost Effective Analysis - This is a more promising tool for application in health field than cost benefit analysis It is similar to cost benefit analysis except that benefit ,instead of being expressed in Monetary terms is expressed in terms of Results achieved eg - No. of lives saved or No. of days free from disease
Social & Preventive Medicine
Definitions and Concepts in HP
4d773a5b-c924-4174-8f52-053225e9abf0
Increased risk of coronary hea disease is seen in?
Type I hyperlipidemia
Type II hyperlipidemia
Type IV hyperlipidemia
Type V hyperlipidemia
1b
single
Ans. is 'b' i.e., Type II hyperlipidemia FRADERICKSON CLASSIFICATION OF HYPERLIPIDEIVRA 1. Type Ilfamilial lipoprein lipase deficiency) o Lipoprotein lipase is required for the hydrolysis of chylomicrons and VLDL tri glycerides. o Deficiency of LPL results in decrease hydrolysis and elevated levels of plasma chylomicro...
Pathology
null
ce0d5a65-f7a4-4a61-8001-ffe8d9f5fffc
Which of the following cannot be done by 3 years old child -
Draw a triangle
Draw a circle
Can arrange 9 cubes
Can go, up and down
0a
single
Ans. is 'a' i.e., Draws a triangle o A child can draw a triangle by 5 years. o A child can draw a circle by 3 years. o A child can make a tower of 9 cubes by 30 months. o A child can go up and downstairs with one step at a time by 2 years. o A child can stand momentarily on one foot by 3 years
Pediatrics
null
eac09546-5051-4ee5-861c-454faf2e595c
Which of the following is false about parotid tumor
Facial nerve involvement indicates malignancy
Pleomorphic adenoma is most common
Superfical parotidectomy is the treatment
Malignant disease is most common variety
3d
multi
Benign tumors are most common parotid gland tumors.
Surgery
null
4bd077a6-2583-44fc-ad4a-cefe8549645b
Characteristic features of opioid withdrawal is:
Rhinorrhea and lacrimation
Seizures
Delirium tremors
Transient visual, tactile or auditory hallucinations
0a
multi
Ref: KDT 6/e p447 *Withdrawal symptoms are opposite of the acute effect of drug. For opioids, these include lacrimation, rhinorrhea, lacrimation, yawning, piloerection, diarrhea, nausea, coughing, mydriasis, sweating and twitching of muscles.
Pharmacology
Central Nervous system
53cf3c6b-ffb1-4703-9709-3601fcc1f6f3
Fetal hemoglobin has more affinity for oxygen than adult hemoglobin because -
Decreased 2,3 DPG concentration
Low affinity for 2,3 DPG
Increase 2,3 DPG concentration
Reduced pH
1b
single
Ans. is 'b' i.e., Low affinity for 2,3 DPG o Make it very clear in mind that higher affinity' of fetal hemoglobin for oxygen is due to low affinity of HbF for 2,3- DPG (not due to decreased 2, 3-DPG concentration). HbF does not combines to 2, 3-DPG as avidly as adult hemoglobin."Fetal hemoglobin is left - shifted becau...
Physiology
Blood: RBCs, Anemia, and Polycythemia
eca82811-1145-4ca4-8af4-8d1c56b3aae7
Transport of two substances in same direction is called as?
Symport
Antiport
Exocytosis
Pinocytosis
0a
multi
ANSWER: (A) SymportREF: Guyton's physiology 22nd ed page 54- 55, Ganong's physiology 22nd ed chapter 1CotransportWhen the transported molecule and cotransported ion move in the same direction, the process is called Symport; when they move in opposite directions, the process is called Antiport UniporterSynporterAntiport...
Physiology
Transport Across Cell Membrane