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135
e8990fe2-1a63-402b-bad4-37c9ff55dc32
Ram Devi presented with generalized edema sweating and flushing tachycardia and fever after bee sting. This is -
T cell mediated cytotoxicity
IgE mediated reaction
IgG mediated reaction
IgA mediated hypersensitivity reaction
1b
single
Ans. is 'b' i.e., IgE mediated reaction o The symptoms of the patient are d/t hypersensitivity type I reaction Type I is mediated by IgE and it flairs up within minutes. o There are typical features of anaphylaxis (systemic Type I hypersensitivity). Clinical manifestations of anaphylaxis o Flushing and tachycardia are ...
Pathology
null
05745e2b-e1d2-4421-a562-6b599ee6f767
DOC for herpes zoster is –
Vidarabine
Acyclovir
Idoxuridine
Aclidine
1b
single
For typical cases of herpes zoster, oral acyclovir is used. Oral famciclovir or valaciclovir have advantage of a more convenient dosing.
Dental
null
26d9f133-126a-4092-a03f-decc928f1671
Culture media used for diagnosis of EHEC 0157 : H7 is:
O7 culture
Sorbitol MacConkey media
XLD Agar
Deoxycholate Media
1b
single
Non- DNA- dependent methods are used for routine diaggnosis of EHEC 0157: H7. This serotype is suggested by isolation of an E-coli that fails to fermant sorbitol on MacConkey sorbitol; latex aggulination confirms. Ref: Kliegman, Behrman, Jenson, Stanton (2008), "Nelson textbook of Pediatrics", Chapter 197, "Escherichia...
Microbiology
null
b6e5c783-8b3e-4957-b3bc-77cec94a79e0
Position of limb in posterior dislocation of hip ?
Flexion, abduction & external rotation
Flexion, adduction & internal rotation
Flexion, adduction & external rotation
Flexion, abduction & internal rotation
1b
single
Ans. is 'b' i.e., Flexion, adduction & internal rotation
Surgery
null
5f4f931e-f94b-4c92-860c-cd940f2e8d0e
A diabetic patient 2 days after post cataract surgery develops develops hypopyon. What will be the management?
Intravitreal antibiotics
Eye drops
Surgery
No treatment required
0a
single
REF : AK KHURANA 7TH ED
Ophthalmology
All India exam
6ab2f9eb-e670-4b61-825e-31b6436a50fd
Which of the following is the most predominant constituent of sulfur granules of Actinomycosis is -
Organisms
Neutrophils and monocytes
Monocytes and lymphocytes
Eosinophils
0a
single
null
Microbiology
null
09e7bd2c-3eda-474f-b33b-659b8b7c6200
Glutathione contains all except-
Cysteine
Glutamine
Glutamic acid
Glycine
1b
multi
Ans. is 'b' i.e., Glutamine* Glutathione is a tripeptide* It is g glutamyl cysteinyl glycine* It is made up of three aminoacids - glutamic acid, cysteine and glycine* Hence Glutamine is not a component of glutathione
Biochemistry
Proteins and Amino Acids
e1a3a36d-852b-4e5a-93ca-3d25c5671a94
Which of the following nerve stimulation may be considered for treatment of ADHD?
Vagal Nerve
Facial Nerve
Trigeminal Nerve
Trochlear Nerve
2c
single
Ans. C. Trigeminal nerveExternal Trigeminal Nerve Stimulation (eTNS) System is indicated for patients ages 7 to 12 years old who are not currently taking prescription ADHD medication and is the first non-drug treatment for ADHD granted marketing authorization by the FDA.
Psychiatry
Miscellaneous
070f21b9-927c-462d-9edc-37ba9323ded8
Denis gave how many columns theory to define stability of spine:
1
2
3
4
2c
single
(c) 3ExplanationDenis' Three-Column Theory- Proposed by Francis Denis, three-column concept divides a spinal segment into three parts: Anterior, middle, and posterior colums.- The anterior column comprises the anterior longitudinal ligament and the anterior half of the vertebral body; the middle column comprises the po...
Orthopaedics
Spinal Injuries
95968480-9a6b-4adb-a226-3cd59878a6ff
Microcytic hypochromic anemia found in infestation of -
Ancylostoma
Ascaris
Necator
Diphyllobothrium
0a
multi
hookworm disease-microcytic,hypochromic anemia Ingest blood Sucks 0.2 ml blood daily Small bleeding point (Refer pgno:146 baveja 3rd edition)
Microbiology
parasitology
e24e70c1-28d3-429c-b2ed-1233a7061886
Cotard's syndrome has ?
Persecutory delusions
Religious delusions
Nihilistic delusions
Hypochondrical delusions
2c
single
Ans. is 'c' i.e., Nihilistic delusions Types of delsions Based on the contents of delusions, they are divided into :- Persecutory delusions (paranoid) : - The patient feels that he is being persecuted against. There is false belief that one is being harmed, threatened, cheated, poisoned, harassed or spied on or is a vi...
Psychiatry
null
bab3570f-1813-42d5-962f-854fa8ed925c
As compared to Cow's milk, Human milk has:
More proteins
Less carbohydrates
More iron
Less of Vitamins
2c
single
Human milk contains higher quantities of Lactose Iron water Vit- A, C Cysteine, Taurine Linoleic acid, lenolenic acid, PUFA Casein: whey ratio Cow milk contain high quantities of Energy Proteins Fats Vit-B, D Na+, K+ Methionine Casein: whey ratio Hence, Comparative contents of nutrients given: Protein : Cow > Human Lac...
Social & Preventive Medicine
Paediatric Care in RCH: BW, BL, PEM, Breast Feeding
886a2305-69db-4fc3-8270-5143c3b6c465
A 74-year-old man presents to the emergency department with new symptoms of blood tinged sputum. For the past week he has noticed streaks of blood in his chronic daily sputum production. He reports no fever or chills, but has lost 10 lb in the past 6 months involuntarily. His past medical history is significant for hyp...
syndrome of inappropriate anti diuretic hormone (SIADH) secretion
acanthosis nigricans
Cushing syndrome
leukemoid reaction
0a
multi
SIADH is more characteristic of small cell lung cancer. Paraneoplastic syndromes are classified as metabolic, neuromuscular, connective tissue, dermatologic, and vascular. Acanthosis nigricans and other cutaneous manifestations (eg, dermatomyositis) are rare (< 1%). Clubbing is common and occurs in up to 30% of non-sma...
Medicine
Respiratory
95233785-336c-4517-9daf-89b1a4903b5e
Bechet's syndrome is characterized by all of the following eye manifestations, EXCEPT:
Posterior uveitis
Iritis
Optic Neuritis
Retinal pigmentation
3d
multi
The eye disease is present in 50% of patients with Bechet's syndrome. It is usually present at the onset but may also develop within the first few years. Iritis, posterior uveitis, retinal vessel occlusions and optic neuritis can be seen in some patients with the syndrome. Note: Scarring and bilateral panuveitis is the...
Ophthalmology
null
f5e99584-2aa9-49c4-b22a-fd3c0163365f
Newborn 7 days old with vomiting and dehydration clinical examination was normal except for by hyperpigmentation of nipple. Electrolytes Na: 120 meq.K: 9 meq. most likely diagnosis -
Primary hypothyroidism
Cong. adrenal hyperplasia
Panhypopituitarism
Pyloric stenosis
1b
multi
null
Medicine
null
8ba0b2db-b75c-4f08-a9d9-9924bc42f13e
A patient presented with normal eyesight and absence of direct and consensual light reflexes in left eye. Which of the following cranial nerves is suspected to be lesioned?
Occulomotor
Trochlear
Optic
Abducent
0a
single
Ans. (a) OculomotorRef: Kanski 7/e, p. 815In complete optic nerve lesion of one side (afferent pupillary defect)The ipsilateral direct reflex is absentThe contralateral consensual reflex is absentIn oculomotor nerve lesion of one side (efferent pupillary defect)The ipsilateral direct reflex is absentThe ipsilateral con...
Ophthalmology
Neuro-Ophthalmology
dd33afdb-d58b-46ac-9994-9f3a3d367ba1
Secretions of GIT are controlled by
Myenteric plexuses
Auerbach plexuses
Meissner plexuses
Extrinsic nerve
3d
single
Secretions of GIT are controlled by the Meissner plexus. Ref: Ganong&;s Review of Medical Physiology 26th edition Pgno: 460
Physiology
G.I.T
d55f0f31-d2c5-4dfd-8337-902f2bdbf139
Proteins are soed by :
Golgi Bodies
Mitochondria
Ribosomes
Nuclear Membrane
0a
single
A i.e. Golgi bodies
Biochemistry
null
531c8f9a-c04a-4201-b5db-1734693e2d29
Not true about IPV is -
Given in 4 doses
Can't be given in AIDS patient
Is a killed vaccine
Also known as salk vaccine
1b
multi
<p> IPV /salk polio vaccine. Strains - Mahoney( salk type 1) MEF1( salk type 2) saukett( salk type 3) Inactivated in formaldehyde. Final vaccine mixture contains 40 units of type1, 8 units of type 2, and 32 units of type3. Administration- intramuscular injection or subcutaneous. Should be refrigerated to ensure no loss...
Social & Preventive Medicine
Communicable diseases
10040108-74f1-48d5-ae80-da89350895fa
Type of collagen found in cailage:
Type I
Type II
Type III
Type IV
1b
single
Collagen has great tensile strength, and is the main component of fascia, cailage, ligaments, tendons, bone and teeth.Along with soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging.It strengthens blood vessels and plays a role in tissue developmen...
Biochemistry
null
f515f84a-aba9-408c-ae16-bff3b22f53a4
Side effect of SSRI
Nausea
Diarrhoea
Weight gain
Rash
2c
single
SIDE EFFECTS Paradoxical SUICIDE, this is a type of suicide where an antidepressant used to treat depression and decrease suicide increase the chance of suicidal attempt ( IT'S A PARADOX). The explanation that is given is SSRI initially activates the patient and decreases fatigue, thus patients with low mood and suicid...
Psychiatry
Pharmacotherapy in psychiatry
56ac3a38-2a21-4481-9167-085469c91a8d
Lymphatic drainage of oropharynx is mainly through
Superficial cervical lymph nodes
Submandibular nodes
Jugulodigastric nodes
Jugulo-omohyoid nodes
2c
single
Lymphatics from oropharynx drain into the upper jugular chain, paicularly the jugulodigastric ( tonsilar) node. Some pas drain to the posterior cervical group also. The base of the tongue may drain bilaterally. Lymphatic drainage of the nasopharynx - upper deep cervical nodes. (Ref: Diseases of Ear, Nose and Throat, PL...
ENT
Pharynx
19b03ca0-c8ef-47a8-b11d-9ea71efb71ea
When treating urinary tract infection (UTI) in the third trimester, the antibiotic of choice should be
Cephalosporin
Tetracycline
Sulfonamide
Nitrofurantoin
0a
single
Although quite effective, sulfonamides should be avoided during the last few weeks of pregnancy because they competitively inhibit the binding of bilirubin to albumin, which increases the risk of neonatal hyperbilirubinemia. Nitrofurantoin may not be tolerated in pregnancy because of the effect of nausea. It should als...
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
e88fe02f-b768-4eca-9d28-32dfb8d67ad7
Which of the following is the most common renal cystic disease in infants is ?
Polycystic kidney
Simple renal cyst
Unilateral renal dysplasia
Calyceal cyst
2c
single
Unilateral renal dysplasia is a form of renal dysplasia (RD; see this term), a renal tract malformation in which the development of one kidney is abnormal and incomplete. Unilateral RD can be segmental, and of variable severity, with renal aplasia corresponding to extreme RD. Reference: GHAI Essential pediatrics, 8th e...
Pediatrics
Urinary tract
82007556-87e1-409b-9197-48e968100234
Which is not a RBC membrane protein?
Ankyrin
Nebulin
Spectrin
Gycophorin
1b
single
The protein skeleton consists of 2D mesh of spectrin tetramers and oligomers. It is attached to RBC membrane by attaching to ankyrin. Membrane proteins like glycophorin also present. Ref: Textbook of medical physiology by N Geetha, 3rd edition, page no. 77
Physiology
Cardiovascular system
2b1619eb-e77e-486f-8dd0-9c697326d0c6
Pneumococcal vaccine is prepared from
Cell surface antigen
Capsular polysaccharide
exotoxin
M protein
1b
single
Pneumococcal vaccine: A polyvalent polysaccharide vaccine representing the capsular antigens of the 23 most prevalent serotypes have been stated to give 80-90% protection. Given in patients with enhanced risk of pneumococcal infection, absent or dysfunctional spleen, sickle cell disease, immunodeficiency etc. It is not...
Microbiology
Bacteriology
a2ec0a95-2f9e-4a1e-a90a-29e5d7ceb4fc
Flabby white lesions occur bilaterally on buccal mucosa of a five-year-old child. The Lesions are a symptomatic the child's mother says this condition is seen in few other members of the family. The lesions are most likely:
Leukoplakia
Lichen planus
Submucous fibrosis
White sponge nerves
3d
multi
null
Dental
null
58a77424-47f6-47ce-9c16-43d22323887c
Kennedy bar is also known as:
Double lingual bar
Lingual plate
Lingual bar
Palatal plate
0a
single
null
Dental
null
a3588f4d-7266-473d-b360-ca88e85312e8
Full blown immunodeficiency syndrome is characterized by -
High viral titres with low CD4 count
Low viral titres with low CD4 count
High viral titres with high CD4 count
High CD4 and high CD8
0a
single
Any HIV-infected individual with a CD4+ T cell count of <200/mL has AIDS by definition, regardless of the presence of symptoms or oppounistic diseases . (Harrison's Principles of internal medicine, 20 th edition, page 1506)
Medicine
Infection
5930c046-6bb9-4f9b-9a7f-6444c9c91f20
True about Zenker's diveiculum is all, EXCEPT:
Originates from the anterior wall of the esophagus
Occurs through triangular area of weakness
It tends to dete from the midline, mostly to the left
None of the above
0a
multi
Zenker diveiculum originates from the posterior wall of the esophagus in a triangular area of weakness, limited inferiorly by the cricopharyngeus muscle and superiorly by the inferior constrictor muscles (ie, the Killian triangle). As the diveiculum enlarges, it tends to dete from the midline, mostly to the left
ENT
null
5fc37b24-114d-4c09-bf99-743b06b5fcbc
In an aphakic eye the anterior focal point from the anterior surface of cornea is about:
15 mm
21 mm
23 mm
31 mm
2c
single
Ans. 23 mm
Ophthalmology
null
2d391417-6615-4691-901a-70fa67d7b70e
Tolerance develops to all of the following effects of opioids except
Constipation
Miosis
Convulsions
All of the above
3d
multi
Decreased effects are seen with continuous usage of opioids except for miosis, constipation, and convulsions.Ref: HL Sharma 3rd ed Pg: 508
Pharmacology
Autacoids
3aea56a2-8ebf-427c-b7e2-5042a189742e
Which of the following describes the pelvic outlet
Angle of pubic arch is less than 90 degrees.
Base of posterior triangle is the coccyx.
Descending inferior pubic rami form lateral boundaries of posterior triangle.
Common base of the two triangles is formed by a line drawn between the two ischial tuberosities.
3d
single
Pelvic outlet consists of 2 triangular areas with a common base, which is a line drawn between the two ischial tuberosities. Angle of pubic arch is 90 → 100 degrees. Lateral boundaries of posterior triangle is formed by sacrotuberous ligaments.
Gynaecology & Obstetrics
null
5de20fc4-64f1-4589-b54f-261fcde24f86
All of the following statements about vincristine are true except
It acts by inhibiting mitosis
It prominent adverse effects is peripheral neuropathy
It does not suppression bone marrow
It is a drug of choice for solid tumors
3d
multi
Vincristine is a vinca allkaloid. It acts in M-phase of cell cycle by inhibiting the formation of spindle. It is a marrow sparing drug and causes peripheral neuropathy as a prominent adverse effect. It is used for the treatment of hematological malignancies like Hodgkin's lymphoma and leukemias.It is ineffective agains...
Anatomy
Other topics and Adverse effects
2eadcedb-6c80-403b-83af-c99bea047b6a
Lipofuscin is associated with
Brownatrophy
White atrophy
Red atrophy
Black atrophy
0a
single
o Deposition of lipofuscin in the heart is referred as brown atrophy
Pathology
null
53c134e3-d9ae-46e6-b018-1918b580acd7
Beefy red, foul smelling genital granuloma with a bleeding ulcer on touch is seen in -
LGV
Chancroid
Primary syphilis
Donovanosis
3d
single
Donovanosis is caused by Klebsiella granulomatis. It&;s morphology is that it is a single(sometimes multiple) asymptomatic ulcer. Floor is made of beefy , exuberant, granulation tissues that bleeds on manipulation. From illustrated synopsis of dermatology and sexually transmitted diseases neena khanna 5th edition page ...
Dental
Sexually transmitted diseases
a2f2b032-1701-4e3d-9c16-29312f5c07a0
A patient who was initially smear positive, who began the treatment and who remained or became smear positive again at five months or later during the course of treatment is called as
Defaulter
Failure case
Relapse
None of the above
1b
multi
Failure case: A patient who was initially smeared positive, who began Rx and who remained or became smear positive again at five months or later during the course of Rx. Relapse: A patient who returns sputum smear positive having previously been treated for tuberculosis and declared cured after the completion of his tr...
Social & Preventive Medicine
Communicable diseases
f46970af-f42b-4f2f-ab34-e6ff5afa4f5a
Which cholesterol is designated as "Good Cholesterol"
VLDL
LDL
HDL
IDL
2c
single
HDL The level of HDL in serum is inversely related to the incidence of ML As it is "antiatherogenic" or "protective" in nature, HDL is known as "good cholesterol".
Biochemistry
null
9f37aa48-703b-4ef6-bc64-43eb037928cd
In JVP, a wave is due to?
Atrial filling
Atrial relaxation
Atrial contraction
Ventricular relaxation
2c
single
Atrial contraction REF: Harrison's Internal Medicine 17th edition Chapter 220 Physical Examination of the Cardiovascular System, http://en.wikipedia.org/wiki/Jugular_ venous_pressure JVP WAVEFORM: Classically three upward deflections and two downward deflections have been described. 1. The " a " wave corresponds to rig...
Physiology
null
dddf13db-aee8-4ec9-a1b9-d5957805b1f0
Common site of regional enteritis is ?
Colon
Rectum
Distal ileum and colon
Caecum
2c
single
Ans. is 'c' i.e., Distal ileum and colon Crohn disease (Terminal ileitis or regional enteritis) Crohn disease (CD) is an inflammatory bowel disease (IBD) which is characterized by ? 1) Sharply delimited and typically transmural involvement of the bowel by an inflammatory process with mucosal damage. 2) The presence of ...
Pediatrics
null
d30d272d-020b-4b50-8570-ae1dfd12b61f
Corrosion product of high copper amalgam
SnO
SnHg
Sn-O Cl
Cu-sn
0a
single
null
Dental
null
96e5f838-43d3-48e7-855e-0a998ba3e3cd
Dorsal surface of pons is related with?
Trochlear nucleus
Motor nucleus of vagus
Hypoglossal
Facial
3d
single
The pons can be broadly divided into two pas: the basilar pa of the pons(ventral) and the pontine tegmentum( dorsal)The pontine tegmentum contains nuclei of the cranial nerves -5,6,7,8 and their associated fibre tracts, the pontine reticular formation, the mesopontine cholinergic system, the laterodorsal tegmental nucl...
Anatomy
Brain
19fd3aed-565b-4c12-9099-db43d4ee3cb6
The given cell is activated by
IL-1
IL-2
IL-5
IL-6
2c
single
TH2 cells secrete IL-4, IL-5, and IL-13, which recruit and activate eosinophils and are responsible for the alternative pathway of macrophage activationReference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 3; Inflammation and Repair
Pathology
General pathology
48881834-1d86-4415-b78d-6df107fad8e8
Commonly used shunt in hydrocephalus management:
Ventriculoatrial
Ventriculoperitoneal
Ventriculopericardial
Ventriculopleural
1b
single
b. Ventriculoperitoneal(Ref: Nelson's 20/e p 2814)Therapy for hydrocephalus:Medical management, including use of acetazolamide and furosemide, can provide temporary relief.Most cases of hydrocephalus require extracranial shunts, particularly a ventriculoperitoneal shunt.The major complications of shunting are occlusion...
Pediatrics
Central Nervous System
836c98b6-66f8-44b4-bfeb-9fb646fad8af
Integrated Management of childhood illness includes except
ARI
Malaria
Diarrhea
TB
3d
multi
IMNCI is Indian adapta on of Global Programme of WHO & UNICEF to reduce childhood morbidity & moality
Pathology
All India exam
add554eb-7a50-4035-9a74-5664f7dce8f4
Pyometra is a complication associated with all of the following conditions except :
Carcinoma vulva
Carcinoma cervix
Carcinoma endometrium
Pelvic radiotherapy
0a
multi
Ans. is a i.e. Carcinoma vulva
Gynaecology & Obstetrics
null
bb832e49-5964-4dfa-8757-345d6a2a4096
Which of the following statement is TRUE about endemic typhus?
Is caused by R. rickettsii
Is transmitted by the bite of fleas
Has no mammalian reservoir
Is caused by Coxiella burnetii
1b
multi
Endemic typhus: Caused by Rickettsia typhi (ubiquitous). Humans usually acquire the infection in an urban or suburban setting when bitten by an infected flea, which releases infected feces while sucking blood. Laboratory diagnosis of rickettsial diseases is based on serologic analysis rather than isolation of the organ...
Microbiology
null
3b0a6985-f3ee-49b3-b055-7e7f7c25ecfb
Clopidogrel is an
Anti hypertensive
Antidiabetic
Antiplatelet
Anticoagulant
2c
single
null
Pharmacology
null
cd693a01-fbf4-4846-8545-3fb27b9fad7e
Contraindication of spinal anaesthesia is –
Hypertension
Renal disease
Clotting disorders
Diabetes
2c
single
null
Anaesthesia
null
6b87c9f5-391d-42c1-8437-72371d3d7753
Urea is formed from which substrate?
Arginine
Orginine
Citruline
Aspaate
3d
single
A. Steps of Urea Cycle: 1. Formation of Carbamoyl Phosphate: Condensation of ammonium ion with bicarbonate ion resulting in the formation of carbamoyl phosphate by the help of the enzyme carbamoyl phosphate synthase-I present in the liver mitochondria. It requires Mg2+ and a dicarboxylic acid i.e. N-acetyl glutamate. T...
Biochemistry
Metabolism of nucleic acids
cfc9a4fa-7eb0-40be-a8fe-bc05e6dcff93
Which of the following statement (s) is/are true about Hb–O2 dissociation curvea) Fetal Hb shifts curve to leftb) Hypothermia shifts curve to leftc) Hypercarbia shifts curve to leftd) Left shift cause more O2 release to tissue
ab
a
ad
bc
0a
multi
Hb-O2 dissociation curve shift to left indicates more affinity of Hb to O2, and thus less delivery of O2 to tissues.   Shift to left seen in -        Increased pH -        Decreased 2,3 DPG, temperature, PCO2 -        HbF (Fetal)   Shift to right seen in -        Decreased pH -        Increased 2,3DPG, temperature, PCO...
Physiology
null
72822ce1-7bdd-4213-a4b7-c1a5695363f9
Dose of iron and folic acid in pregrnancy is -
20 mg iron and 100 mcg FA
30 mg iron and 250 mcg FA
100 mg iron and 500 mcg FA
100 mg iron and 100 mcg FA
2c
single
During pregnancy, 100 mg iron and 500 mcg FA should be given. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 594
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
1be32fcc-0ab6-4a58-8c78-a637b9d28430
Black gun powder composition ?
Charcoal 60% + Potassium nitrate 20% + sulphur 20%
Charcoal 25% + Potassium nitrate 70% + sulphur 05%
Charcoal 15%+ Potassium nitrate 75% + sulphur 10%
Charcoal 65% + Potassium nitrate 20% + sulphur 15%
2c
single
Ans. is 'c' i.e., Charcoal 15% + Potassium nitrate 75% + sulphur 10% The classical gun powder is known as black powder, consists of charcol (15%), Sulphur (10%), and potassium nitrate (75%). Depending on fineness, the black gun powder is designated as FG, FFG, FFFG. etc. (F = fineness). Pyrodex is another gun powder wi...
Forensic Medicine
null
c8772169-4d76-4820-91b2-18f43b81a457
What does the arrow point to in the fundus examination of a myopic patient?
FosterFuchs spot
Lacquer cracks
Arlt line
Myopic crescent
0a
single
Fundus findings in degenerative myopia:1A pale tessellated ('tigroid') appearance is due to diffuse attenuation of the RPE with visibility of large choroidal vessels.2Focal chorioretinal atrophy is characterized by the visibility of the larger choroidal vessels and eventually the sclera.3Anomalous optic nerve head whic...
Ophthalmology
Vitreous and retina
02243e1a-2cec-4556-b273-ec07208cda06
Corpus leuteum stas regressing after how many days of ovulation ?
5 days
10 days
24 days
None
1b
multi
Ans. is 'b' i.e., 10 daysIf ovum is not feilized, the corpus luteum stas degenerating around day 24 of cycle (about 10 days after ovulation) and is eventually is replaced by fibrous tissue, forming corpus albicans.Degeneration of corpus luteum is due to decline in level of LH (which is required for maintenance of corpu...
Physiology
null
5d0fe05c-3bc1-4732-a472-8e592bedc78d
Mildly elevated bilirubin, normal liver enzymes are seen in?
Malaria
Thalassemia
G-6 PD deficie
All of above
3d
multi
Ans. is 'd' i.e., All of above
Pediatrics
null
173febf1-ce0f-4bff-b74d-0c9f6f1173ff
Which of the following is the first immunoglobulin to appear following infection?
IgG
IgM
IgA
IgE
1b
single
IgM is the first immunoglobulin to appear after exposure to an antigen. They are relatively sho lived hence their demonstration in the serum indicates recent infection. Normal level of IgM is 1.2mg/ml. It is also the earliest to be synthesized by fetus beginning by about 20 weeks of age. As it cannot cross the placenta...
Microbiology
null
674108b9-4267-44db-bccb-483f205c674a
Which embryonic structure forms philtrum of upper lip
Maxillary process
Mandibular process.
Medial nasal process.
Lateral nasal process.
2c
single
null
Anatomy
null
78d51779-e06a-4b5a-8edc-d119dbde5eef
Anti-craving agents for alcohol dependence are all except aEUR'
Lorazepam
Acamprosate
Topiramate
Naltrexone
0a
multi
Lorazepam Management of alcohol intoxicationDrugs used areLorazepam (can worsen the vitals because of C.N.S. depression)Haloperidol (can lower the seizure threshold)Other drugs which may be usedZiprasidoneOlanzapineManagement of alcohol withdrawlAll patients should be given oral multiple vitamin B1including 50-100 mg o...
Psychiatry
null
5a7f96e7-8f9e-48b7-a499-0fa0a8b20c6d
A 5-year old male child has been brought with a complaint that there is only one testis in the scrotum. On examination, it is found that the testis on the opposite side is felt in the inguinal canal. The patient should be advised?
Orchiopexy
To wait till pubey
Orchidectomy
Administration of androgens
0a
single
Ans. is 'a' i.e., Orchipexy
Surgery
null
3cbdfa54-372b-4007-a601-efbcc180adf4
Hemophilia is associated with which chromosome ?
X
Y
13
8
0a
single
Hemophilia A and B - X linked recessive disorders. Hemophilia C - Autosomal recessive disorder. X linked recessive disorders SYSTEM DISEASE Musculoskeleton Duchenne Muscular dystrophy Blood Hemophilia A,B Chronic Granulomatous disease G-6-PD deficiency Immune Agammaglobinemia Wiskott-Aldrich Syndrome Metabolic Diabetes...
Pathology
Clotting factor
6d1a5ac7-2e55-447f-80be-b3a623ae6830
Rate limiting enzyme in gluconeogenesis -
Phosphofructokinase-1
Pyruvate kinase
Fructose 1-6 bisphosphatase
Glucokinase
2c
single
Ans. is 'c' i.e., Fructose 1-6 bisphosphatase Most imp step =Pyruvate carboxylase, Only step at ER= G 6 Phosphatase RLS - F 1-6 Bisphosphatase. o Gluconeogenesis involves glycolysis, the citric acid cycle plus some special reactions. Glycolysis and gluconeogenesis share the same pathway but in opposite direction. Seven...
Biochemistry
Gluconeogenesis
e0550b1a-21d3-452e-94ce-36b5910bfab2
Most common organism causing neonatal meningitis is
E. coli
Listeria
Pseudomonas
Staph aureus
0a
single
The most common causes of neonatal meningitis is bacterial infection of the blood, known as bacteremia (specifically group B streptococci (Streptococcus agalactiae), Escherichia coli, and Listeria monocytogenes . Reference: GHAI Essential pediatrics, 8th edition
Pediatrics
Central Nervous system
ee31b90b-5445-4b6a-af79-6792157900b8
Loosening of association is an example of which of the following thought pathology?
Perseveration
Concrete thinking
Formal thought disorder
Schneiderian first rank symptoms
2c
single
Loosening of associations is an example of formal thought disorder, which is a disturbance in the form of thought rather than content of thought. It is a characteristic feature of schizophrenia.Loosening of association refers to lack of connection between the ideas expressed by the patient. The links between ideas may ...
Psychiatry
null
b26aca0a-381f-487d-ad5c-ea256eae595d
Virus that has association with anal warts?
HPV
HIV
LMV
EBV
0a
single
Ans. a (HPV) (Ref. Bailey and Love 24th ed., 61.6)WART# It is a HPV-induced tumor-like lesion known to spontaneous resolution.# Transmission is by direct or intimate contact, the virus material usually being inoculated through an abrasion.# It is well recognised that patients with immune deficiencies develop widespread...
Surgery
Disorders of the Anal Canal
69b293d4-b2d5-41ee-bb87-f2b21b1bb194
A person comes into your ER room with a very weak pulse after a suffering a heart attack. You suspect:
The weak pulse has nothing to do with shock or the heart attack, so send him home.
A late stage (decompensated) shock, the least life-threatening stage of shock.
A very early stage (compensated) shock, the most life-threatening stage of shock.
A late stage (decompensated) shock, the most life-threatening stage of shock
3d
single
D:  A very weak pulse shows that the heart is slowly ceasing to function as a result of pumping too hard. A: The patient should not be sent home; close observation is necessary. B: This stage is a life-threatening stage as the heart could tire itself out and stop functioning. C: An early stage of shock shows a rapid, b...
Medicine
null
e54f486a-4313-41a4-9d1d-1822d73c60c7
Commonest cause of death in peptic ulcer patients is -
Perforation
Hemorrhage
Pyloric stenosis
Maliganancy
1b
single
null
Surgery
null
3835f6d7-c8bc-474d-bfba-0a24b0b9e322
Obesity predisposes to all, except ?
Diabetes
Colon cancer
Lung cancer
Breast cancer
2c
multi
Ans. is 'c' i.e., Lung cancerObesity increases the risk of following diseases :-Greatly increased risk : NIDDM, gall bladder disease, insulin resistance, dyslipidaemia, sleep apnea and breathlessness.Moderately increased risk : Type-2 DM, hypeension, CHD, osteoahritis (knee), hyperuricemia and gout.Slight increased ris...
Social & Preventive Medicine
null
5a4dc59a-3894-4b21-94d7-ae15cd65c29a
Kleiheur Bethke test is done for?
Cephalopelvic disproportion
Fetomaternal haemorrhage
Determining karyotype of normal fetus
Diagnosing fetal infections
1b
single
Ans. (b) Fetomaternal haemorrhage(Ref: Oski's Pediatrics: Principles & Practice, chapter 66; Dacie 11th/pg 307)APT test for differentiation of fetal & adult (maternal) hemoglobin in stool or vomitusMix 1 volume of sample with 5 volumes of water.Centrifuge mixture and remove clear-pink supernatant solution containing he...
Pathology
Misc. (R.B.C)
9b493010-e148-4a6a-b26c-0214b693a923
In the video you can see a testicular procedure being done. This is the testicular sperm aspiration for azoospermic men. Which of the following procedures can be performed to help this couple have a successful embryo formation in the A "Assisted Reproductive Technology" Lab.
Intra cytoplasmic Sperm Injection
In Vitro Feilization
Intra Uterine Insemination
Intra Vaginal insemination of the aspirated sperms
0a
single
ICSI can be performed to help this couple have a successful embryo formation in the A In this one sperm is directly injected into mature egg prior to intrauterine transfer of the feilized eggs ICSI should be offered if the semen analysis shows <5 million motile sperm, | or absent motility of sperms. Many abnormal sperm...
Gynaecology & Obstetrics
Infeility (Eggs'plantation!)
0a6afecc-fd25-4666-9aa1-6604604a57f7
Nitisinone is an example of
Enzyme activation therapy
Enzyme replacement therapy
Substrate addition therapy
Substrate reduction therapy
3d
multi
Nitisinone is prescribed for infantile tyrosinemia because it decreases production of the substrate (fumarylacetoacetate) for the hydrolase, thus decreasing the velocity of the reaction preventing substrate accumulation.
Biochemistry
Phenylalanine and Tyrosine metabolism Detail
b3db1611-8fcb-4ef9-99b3-82e5eac51d4d
In which one of the following infection dendritic ulcer is seen?
Herpes simplex
Measles
Pseudomonas
Gonococcal infection
0a
single
A dendritic corneal ulcer is the hallmark sign of HSV infection, accompanied by stromal keratitis in more severe infection. These ulcers may begin as nondescript punctate keratopathies but quickly coalesce to form the familiar branching patterns. Because the virus invades and compromises the epithelial cells surroundin...
Ophthalmology
null
9996b317-f498-4c47-9890-ca9b2a5d8f99
Durkheim work wras related to -
Recommendation of multipurpose worker
Management in Health manpower
Division of labor
Integration of medical and health services
2c
single
Ans. is 'c' i.e., Division of labor o Four major works of Durkheim are1) Division of Labor in society.2) Rules of sociological methods.3) Suicide4) Elementary forms of religious life.
Social & Preventive Medicine
Health Planning and Management
e79ba591-027f-4f27-a282-79150c47c629
The hea lesion not found in Congenital Rubella infection is:
ASD
VSD
PDA
PS
0a
single
Answer is A (ASD) ASD is the single best answer of exclusion. Cardiac anomalies in congenital rubella are mentioned differently in different books ! We have chosen ASD as the one to be excluded as both GHAI & CPDT mention VSD as a finding is cases of congenital rubella. Neveheless Harrison mentions ASD as well, and so ...
Medicine
null
6731c08c-ef84-4c1e-a5bf-635c272ca9d7
Acute physiology and Chronic Health Evaluation (APACHE) scoring system is used as a scoring system to -
To predict postoperative cardiac risk
To predict postoperative pulmonary complications
To evaluate prognosis in the critical care settings
To evaluate prognosis after acute myocardial infarction
2c
single
null
Medicine
null
19e09a43-55bd-4e41-a3c8-929ddf833462
Lesions in Face -- False statement is:
Suture done as early as possible
Full thickness graft is used
Suture perpendicular to Langer's line
Stitch removed at 2 weeks
3d
multi
Ans. (d) Stitch removed at 2 weeksRef: Bailey and Love 27th edition, Page 93* Repair face wounds as early in <24hours* In case of grafting -- Full thickness graft taken from behind ear gives good cosmetic match* Incision is always done parallel to Langer's lines and sutures are made perpendicular to them for cosmetic a...
Surgery
Plastic & Reconstructive Surgery
f2e31b0d-af81-48cb-ac6c-9345c5382db2
Sirolimus is more likely than cyclosporine to cause:
Hypeension
Osteoporosis
Renal insufficiency
Thrombocytopenia
3d
single
(Ref: KDT 6/e p840) Cyclosporine and tacrolimus cause nephrotoxicity as an adverse effect. Sirolimus (rapamycin) results in bone marrow suppression and thus may cause anemia, thrombocytopenia and leukopenia.
Pharmacology
Other topics and Adverse effects
2889f907-c3c0-48e7-a104-f4f06bc46dbf
Intraepidermal blisters are seen in all of the following condition excepts
Pemphigus foliaceous
Pemphigus vulgaris
Paraneoplastic pemphigus
Pemphigoid
3d
multi
Level of cleavage & blistering disorders- IADVL textbook of dermatology, page 1088 Intraepidermal Subcorneal / granular/upper spinous 1. Pemphigus erythematosus 2. Pemphigus foliaceous 3. Subcorneal pustular dermatosis 4. IgA pemphigus subscorneal pustular dermatosus type 5. Bullous congenital icthyosiform erythroderma...
Dental
Vestibulobullous disorders
fb9f4ae7-5146-4823-830b-0bddc69543ff
Which of the following has least ability to regenerate?
Liver
Bone
Collagen
Striated muscle
3d
single
null
Pathology
null
b4a5d449-9209-4fed-94c3-09a7c3ea169b
Pityriasis rosea clears with in?
1-2 weeks
2-4 weeks
4-8 weeks
6-12 weeks
3d
single
Ans. is 'd' i.e., 6-12 weeks * P. rosea is self limiting disease, subsides with 6-12 weeks.Pityriasis rosea* P. rosea is a common scaly disorder, occuring usually in children and young adults (10-35 years). Characterized by round/oval pink brown patches with a superficial, centrifugal scale, distributed over trunk in a...
Skin
Miscellaneous
ccba9258-e5a3-4b2f-8dd8-50164911e229
Phenol red test/ Methyl red thread test for dry eye, true is
Need instillation of anesthesia before doing the test
Need a ph meter to interpret
Color changes if there is mucin deficiency
Color changes from white to red on contact with tear film and is used to measure the dryness status of eye
3d
multi
Phenol Red Thread test is the test to detect dry eye severity. When in contact with tear film it changes its colour from white to yellow to red. Its main advantage over Schirmertest is: a)It is Less time consuming as compared to schirmer test(15 sec) b)Anaesthesia of cornea is not required c)On the contact of tear stri...
Ophthalmology
Nasolacrimal Disorders
f66dc075-7940-4ab1-aefe-eaca788c77c3
Which of the following radioisotopes is commonly used as a source for external beam radiotherapy in the treatment of cancer patients?
Strontium-89
Radium-226
Cobalt-59
Cobalt-60
3d
single
Ans. Cobalt-60
Radiology
null
720ad3f8-bd97-46ef-a3d2-956bfcc20fee
The antero-posterior diameter of the lens is increased in all except
Intumescent cataract
Accommodation
Weill-Marchesani syndrome
Morgagnian cataract
3d
multi
Ans. (d) Morgagnian cataractOption a - In cortical cataract, due to progressive hydration, swelling (increase in AP diameter) of the lens occurs making the anterior chamber shallow.Option b - Increase in the anterior lens capsule curvature with axial lens thickness due to the action of ciliary muscle on zonules.Option ...
Ophthalmology
Lens
e3afdb34-2f23-46b1-8c92-7f55457236bd
Earliest sign in X-ray in TB spine-
Paravertebral shadow
Narrowing of disc space
Gibbus
None of the above
1b
multi
Ans- B Narrowing of disc space First clinical sign of TB Spine = Paraspinal muscle spasm First clinical sign of Pott paraplegia = Ankle Clonus > Extensor Plantar > Spasticity First X-ray Sign of Pott spine = Reduction of disc space End result of Pott spine = bony ankylosis Loss of Spinal curvature is a non specific X-r...
Unknown
null
e21c572c-7641-4ba0-93f8-aca084487f50
Which of the following Anti neoplastic drugs SHOULD NOT be given by rapid IV infusion?
Cyclophosphamide
Cisplatin
Bleomycin
Cytosine arabinoside
1b
single
Ans. is `b ' i.e., Cisplatin o Cisplatin is the most common culprit causing chemotherapy induced nausea and vomiting, therefore cisplatin is given as slow i.v. infusion(never bolus) to prevent vomiting.
Pharmacology
null
2d043eeb-a1c2-43c9-acb4-594b6e1c37df
Aspirin is contraindicated in a patient who is on treatment with:
Prednisolone
Warfarin
Theophylline
Oral contraceptives
1b
single
Aspirin can displace warfarin from protein binding sites elevating the free drug level, leading to prolongation of both bleeding time and prothrombin time. So it should not be used in patients on anticoagulation therapy due to increased risk of bleeding. Other drugs which were found to increase the level of warfarin ar...
Pharmacology
null
0a568a27-c005-445f-ab2f-fee777a5790c
Cause of sudden loss of vision in a diabetic is due to:
Neovascular glaucoma
Central retinal aery occlusion
Vitreous hemorrhage
None of the above
2c
multi
Commonest cause of sudden loss of vision in a diabetic is vitreous hemorrhage Slow loss of vision in a diabetic is due to Cystoid macular edema Neovascular glaucoma
Ophthalmology
FMGE 2018
0d519093-8331-441f-8118-45dcb2621092
Late hyperglycemia in pregnancy is associated with
Macrosomia
lUGR
Postmaturity
Congenital malformation
0a
single
Fetal macrosomia Definition: Those infants exceeding the 90th percentile for a given gestational week are usually used as the threshold for macrosomia or large-for-gestational age (LGA) bihweight The primary effect attributed to gestational diabetes is excessive fetal size or macrosomia Maternal hyperglycemia prompts f...
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
5f48d90a-b7aa-43dd-8402-ca6ecee6ebc9
PMA index is used to record the status of:
Gingival disease
Carious teeth
Root caries
Periodontal disease
0a
single
null
Dental
null
9783eb08-29c3-4ae5-8587-366082dcd36a
All are features of emergence delirium with ketamine anesthesia except:-
Visual illusions
Coical blindness
No hallucination
Auditory, proprioceptive and confusional illusions
2c
multi
Despite its reputation as a hallucinogen, sub-anesthetic ketamine does not consistently produce frank hallucinations. 5 - 30 % patients receiving intravenous ketamine has incidence of postoperative delirium and hallucination associated with it. prevention and treatment - intravenous midazolam
Anaesthesia
Intravenous Anesthetic Agents
8d7fa9d7-af76-416e-a8d9-d6640a839701
Phlegmon is a
Sexually transmitted disease
Type of celtulites
Type of osteomyelitis
Venereal disease
1b
multi
null
Pathology
null
38b22b85-984d-443c-81a8-98d537b2b8e0
Which of these fatty acids is found exclusively in breast milk:
Linolaete
Linolenic
Palmitic
Docosahexanoic acid
3d
single
D i.e. Docosahexanoic Acid Most of the naturally occurring unsaturated fatty acids are cis-isomers. Trans-FA do not occur naturally in plants and occurs only in small amounts in animals as ruminant fat (eg butter fat) arising from the action of micro organisms in rumen. Cis isomers are less stable than trans FA.- Trans...
Biochemistry
null
543f0aeb-eed5-4869-9ac1-884909e1a46c
Mixed parotid tumour arises from -
Epithelium
Epithelium + Mesenchymal
Mesenchymal
None of the above
1b
multi
null
Surgery
null
4f34d9df-b78c-41a2-b43b-9dda2c8affd9
A pregnant lady presented with painless bleeding in the 3rd trimester. Most common cause will be
Placenta previa
Abruptio placentae
Vesicular mole
none
0a
multi
Ans a Ref: Sheila balakrishna obs, page 157Clinical features of placenta previaSymptomsClassical presentation of painless antepartum haemorrhage. Recurrent initial bleeding is unusually not severeSignsPallor proportionate to amount of bleedingSize of the uterus correspond to period of amenorrhoeaUterus soft, non tender...
Surgery
Miscellaneous
3453950d-ac35-4677-83ea-9b562e94d8e9
Drugs used in ADHD are –
Atomoxetine
Methylphenidate
Dextroamphetamine
All the above
3d
multi
null
Pediatrics
null
9e384746-9205-4554-aff1-2c6df103b8ba
Which of the following is a mitochondrial enzyme of Urea Cycle
Arginase
Carbamoyl Phosphate synthetase I
Arginosuccinate lyase
Arginosuccinate synthetase.
1b
single
CPS - I is a mitochondrial enzyme and catalyses rate limiting step of Urea Cycle. All the Cytoplasmic enzymes of urea cycle start with letter "A".
Biochemistry
null
9e879d62-0a47-4443-aa5e-1cd2aad4fbdc
On electron microscopy amyloid characteristically exhibits:
B-plated sheets
Hyaline globules
7.5-10 nm fibrils
20-25 nm fibrils
2c
multi
Propeies of Amyloid Proteins: -Physical Nature of Amyloid: Electron microscopy-- Continuous, non-branching fibrils with a diameter of approximately 7.5 to 10 nm. X-ray crystallography and infrared spectroscopy-- Cross-b-pleated sheet conformation. This conformation is responsible for the distinctive Congo red staining ...
Pathology
Amyloidosis
d92be5bd-1d67-4ea0-9e60-01fb598ce63e
New name of mental retardation according to American Association of Mental Retardation:
Feeble Mindedness
Madness
Intellectual disability
Mentally unstable
2c
multi
Ans. c. Intellectual disabilityRef: First Aid for the Psychiatry Clerkship 4th Ed; Page No-122-23Intellectual disability (ID, intellectual developmental disorder) replaces the term mental retardation (MR) as per US law (Rosas Law), with the intention of decreasing stigmatization.ID is characterized by severely impaired...
Psychiatry
Mental Retardation
79e642b8-e423-4b53-a3d1-57977ea565e4
A 35-year-old man has had increasing dyspnea for the past 24 hours. A chest radiograph shows large, bilateral pleural effusions. Thoracentesis yields 500 mL of slightly cloudy yellow fluid from the right pleural cavity. Cytologic examination of the fluid shows many neutrophils, but no lymphocytes or RBCs. Which of the ...
Arteriolar vasoconstriction
Endothelial contraction
Inhibition of platelet adherence
Lymphatic obstruction
1b
single
Exudation of fluid from venules and capillaries is a key component of the acute inflammatory process. Several mechanisms of increased vascular permeability have been proposed, including formation of interendothelial gaps by contraction of endothelium. This contraction can be caused by mediators such as histamine and le...
Pathology
Inflammation & Repair
39c76adb-bf3f-4924-b11a-b47337e88195
A 13-year old girl came to the casualty with acute lower abdominal pain. She had a cyclical pain for the last 6 months. She has not yet attained her menarche. On examination, a tense bulge was seen in the region of the hymen. The most probable diagnosis is?
Mayer-Rokitansky-Kuster-Hauser syndrome
Imperforate hymen
Asherman's syndrome
Congenital adrenal hyperplasia
1b
single
Imperforate hymen: congenital disorder where a hymen without an opening completely obstructs the vaginal outflow. Prevents the drainage of menstrual blood. This results in the accumulation of blood in the vagina leading to hematocolpos. This is visualised as the tense bulge. In long standing cases it can even lead to h...
Gynaecology & Obstetrics
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception