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135
5d6a33ef-b45b-4134-941c-125242ed0d97
Normal capacity of the renal pelvis is
7 ml
10 ml
15 ml
20 ml
0a
single
• The average capacity of the renal pelvis is 4–8 ml.
Surgery
null
8aeadeb9-403f-4958-a71b-bb6e338552be
Nitric oxide acts by:
cGMP
cAMP
Calcium
Kinase
0a
single
Ans: A (cGMP) Ref: Harper's Illustrated biochemistry, 28th edition.Explanation:Classification of Hormones by Mechanism of ActionI. Hormones that hind to intracellular receptors* Androgens* Calcitriol (1.252-D3) Estrogens* Glucocorticoids* Mineralocorticoids* Progestins* Retinoic acid* Thyroid hormones (T3 and T4)II. Ho...
Biochemistry
Proteins and Amino Acids
492c499e-8fdb-4811-b668-bef281b7877f
The law relating distending pressure and tension in a blood vessel wall is called:
Frank Starling's law
Einthoven's law
Law of Laplace
Many's law
2c
multi
Law of Laplace states that transluminal pressure varies inversely with vessel radius and is directly propoional to tension that develops in the vessel walls. It means the pressure pushes against the wall causing them to stretch(tension), as the size of the vessels decreases the tension in the wall decreases too. Law of...
Physiology
null
4e1ce8a4-c144-446a-9f12-f6eb1ce71bb6
Which of the following are goals of orthognathic surgery?
To improve facial esthetics
To shorten orthodontic treatment time
To improve orthodontic treatment results
All of the above
3d
multi
The goals of ortho esthetics are: To improve facial esthetic and self-image of patient. To shorten orthodontic treatment time and improve orthodontic treatment results. To improve PDL stability and prognosis. To correct jaw relationships prior to major restorative procedure.
Dental
null
d003cb01-dff2-41f6-af9b-19f16fa34e74
'Rule of Nine' to estimate surface area of burns was given by:
Moiz Kaposi
Alexander Wallace
Joseph Lister
Thomas Barclay
1b
multi
Ans. B i.e. Alexander Wallace
Surgery
null
0fdc18b3-2d73-4f3c-b975-37e5e9f25569
The most predominantly occurring amino acid in collagen is
Valine
Cysteine
Arginine
Glycine
3d
single
Tropocollagen, the repeating unit of a mature collagen fiber, consists of three collagen polypeptides, each containing about 1000 amino acids, bundled together in a unique conformation, the collagen triple helix. Every third amino acid residue in collagen is a glycine residue. Collagen is also rich in proline and hydro...
Biochemistry
Structure and function of protein
fc26c1fc-2dd8-4341-a5be-e3ca0d176f09
Fluid of choice in child with bu rn < 24 hour is -
Fresh frozen plasma
Isolye-P
Ringer lactate
Plailet tranfusion
2c
single
Ans. is 'c' i.e., Ringer lactate Fluid resuscitation in burn injuryo Parkland formula Initial 24 hours: Ringer's lactated (RL) solution 4 mL'kg/% bum for adults and 3 ml/kg/% bum for children. RL solution is added for maintenance for children:4 ml'kg/hour for chiIdren weighing 0-10 kg40 ml/hour+2 ml.'hour for children ...
Pediatrics
Fluid and Electrolyte Treatment of Specific Disorders
f9f479c0-1029-461c-9c93-3e7211816f93
All are causes of infantile tremor syndrome EXCEPT:
Malnutrition
Magnesium deficiency
Infections
Vitamin B1 deficency
3d
multi
Vitamin B1 deficency REF: OP Ghai ed p. 558 Vitamin B 12 deficiency not B1 deficiency causes infantile tremor syndrome Causes of infantile tremor syndrome: Malnutrition Vitamin B12 deficiency Infections Magnesium deficiency Toxins Tyrosinase defects
Pediatrics
null
2f6420d5-ec3a-4a9d-8327-4f254444eb70
True statement regarding SLE in children-
Skin pigmentation more common than adults
No sex difference
Renal involvement more common
None
3d
multi
Ans. is None
Pediatrics
null
5d32cfd4-424e-47e7-abbd-2cf0ca4857c3
An anxiolytic benzodiazepine which is also antidepressant : September 2007
Lorazepam
Oxazepam
Alprazolam
Chlordiazepoxid
2c
single
Ans. C: Alprazolam Alprazolam is approved for the sho-term treatment of panic disorder, with or without agoraphobia. Alprazolam is very effective in the sho-term symptomatic relief of moderate to severe anxiety, essential tremor, and panic attacks. Alprazolam is indicated for the management of anxiety disorders or the ...
Pharmacology
null
fd10d1e9-ab22-4693-ab5e-47f01a9fe2c0
Synthesis of secretory proteins takes place in
Golgi complex
Endoplasmic reticulum
First in cytoplasm then in nucleus
First in endoplasmic reticulum then in cytoplasm
1b
single
Secretory proteins are synthesized in EPR Reference: Harper; 30th edition
Biochemistry
Structure and function of protein
7fe3cc0e-cb7a-48a3-8e65-a03450551e33
All muscles of the palate are supplied by pharyngeal plexus, EXCEPT:
Tensor veli palatine
Palatoglossus
Palatopharyngeus
None of the above
0a
multi
With the exception of tensor veli palatini, which is supplied by the motor branch of the mandibular division of the trigeminal through the nerve to medial pterygoid, the muscles are supplied by the cranial pa of the accessory nerve the pharyngeal plexus.Ref: Gray's anatomy 40th edition, Chapter 35
Anatomy
null
29a7c47a-69ef-4552-b026-73e84c2d22be
in whic of the following cardiac condition PULSATILE LIVER AND ASCITES is seen ?
TR
Critical pulmonary stenosis
MR
MS
0a
single
Most commonly, TR is secondary to marked dilation of the tricuspid annulus from RV enlargement due to PA hypeension. Functional TR may complicate RV enlargement of any cause, including an inferior MI that involves the RV. It is commonly seen in the late stages of hea failure due to rheumatic or congenital hea disease w...
Medicine
C.V.S
132df81e-37b8-4ce8-8f96-57908cc231bd
Which is not seen in tuberous sclerosis?
Astrocytoma
Ependymoma
White matter lesions
Subpendymal nodules
1b
single
Tuberous sclerosis characterized by angiofibroma,astrocytoma,subependymal lesion and white matter lesion. Ref : Ghai essential of pediatrics, eighth edition, p.no:586
Pediatrics
C.V.S
40c34aed-a15f-425c-aa17-92165547d8ff
Amyloid is stained with: September 2009, March 2013
Lugol's iodine
Methyl violet
Congo red
Sudan black
2c
single
Ans. C: Congo red
Pathology
null
60f5a98d-c460-4900-972f-b81b8e087eca
A 55 year old female comes to the eye casualty with history of severe eye pain, redness and diminished vision. On examination, the visual acuity is 6/60, there is circumcorneal congestion, corneal oedema and a shallow anterior chamber. Which of the following is the best drug of choice –
Atropine ointment
IV mannitol
Ciprofloxacin eye drops
Betamethasone eye drops
1b
multi
Approach in acute congestive glaucoma Start i.v. mannitol or i.v. acetazolamide When IOT starts falling, start topical pilocarpine or β-blocker (timolol). Apraclonidine/latanoprost may be added. Once i.o.t. is reduced, surgery is done.
Ophthalmology
null
dea92445-1202-4995-8c29-8b37f077f99e
Phase 4 clinical trial is carried out -
Before the marketing approval of a drug
After a drug is marketed
For drugs used in rare diseases
For drugs used in pediatric patients
1b
single
Ans. is 'b' i.e., After a drug is marketed Phase 4 clinical trial is post marketing survellance.
Pharmacology
null
e9364aeb-e188-4b45-bde6-589831cf66b3
Charlie chaplin gait is seen in?
Congenial coxa vara
Tibial torsion
DDH
Genu valgus
0a
single
Ans. is 'a' i.e., External rotation deformity of tibia Charlie Chaplin Gait Gait that occurs in bilateral external torsion of the tibia caused by faulty sitting or sleeping habits as in maintenance of the spread eagle or frog leg posture. It is seen in alkaptonuria, bilateral external tibial torsion, and flat feet with...
Surgery
null
d8ee3fce-d3c7-4c4a-b5b8-10b89f9b44cf
Which of the following is not a component of Gradenigo's syndrome?
Deep seated orbital pain
Greisinger sign positive
Abducent nerve palsy
Discharge from ear
1b
single
Discharge from ear is not present in gradeinigo syndrome. Gradenigo Syndrome (GS) is classically described as a clinicaltriad of otitis media, facial pain, and abducens palsy that in the past most commonly developed from infection in the petrous temporal bone (i.e., petrous apicitis). Ref ganong's review of medical phy...
Physiology
All India exam
67a691f6-7088-4b0c-81c1-dcc4c1a10429
Which cells are absent in the cerebellar coex
Purkinje cells
Bipolar cells
Granule cells
Golgi cells
1b
single
There are five types of cells in the cerebellum Purkinje cells, Stellate cells, Golgi cells, Basket cells, Granule cells Ref : Ganong 25th ed/page 248
Physiology
Nervous system
bb6dab88-73a5-445b-9ccc-ed534ace1d81
RDA of vitamin A in an adolescent female ?
400 mcg
350 mcg
600 mcg
800 mcg
2c
single
Ans. is 'c' i.e., 600 mcg
Social & Preventive Medicine
null
eee66082-9520-47bc-9999-4a288e6e5ed2
Bronchiectasis means .....................of bronchi -
Inflammation
Dilatation
Cavitation
All
1b
multi
Ref:Textbook of pathology (Harsh mohan)6th edition, page no.484 BRONCHIECTASIS Bronchiectasis is defined as abnormal and irreversible dilatation of the bronchi and bronchioles (greater than 2 mm in diameter) developing secondary to inflammatory weakening of the bronchial walls. The most characteristic clinical manifest...
Pathology
Respiratory system
4a20c6ed-cc94-43e8-8a75-13d4fdcde87d
Degloving injury is: March 2013 (h)
Surgeon made wound
Lacerated wound
Blunt injury
Avulsion injury
3d
single
Ans. D i.e. Avulsion injury Degloving injury It is a type of avulsion in which an extensive section of skin is completely torn off the underlying tissue, severing its blood supply. It is named by analogy to the process of removing a glove. Typically, degloving injuries affect the extremities and limbs.
Surgery
null
a79abaa3-fc25-4ca7-8de3-8cfb426ff4d6
True statement about the paralysis of the recurrent laryngeal nerve is
Common on left side
50% idiopathic
Cord will lie laterally
Speech therapy given
0a
multi
Paralysis of recurrent laryngeal nerve common on the left side. The common causes are Bronchogenic cancer Accidental trauma Thyroid surgery Thyroid disease (benign or malignant) Cervical lymphadenopathy Carcinoma cervical oesophagus Carcinoma thoracic oesophagus Aortic aneurysm Mediastinal lymphadenopathy
ENT
null
c759f002-d46b-414f-ba92-1b8ad31ee46c
A 10 yr old boy, unconscious with 2 days h/o fever, comes to pediatric ICU with R.R 46/min, B.P.110/80 and E1 V1 M3 on Glasgow coma scale, next step of Mx includes
Intubate and ventilate
Give 0.9% NaCl
Sta dopamine at the rate of 1-2 g/min/kg
Dopamine at the rate of 1-2 g/min/kg & furosemide
0a
multi
There is increased respiratory rate.the child must be intubated and venilated to provide suppo . Reference: GHAI Essential pediatrics, 8th edition
Pediatrics
Central Nervous system
b5e90eeb-0969-4829-a165-4dc3e824d314
Which of the following colonic polyps is not premalignant
Juvenile polyps
Hamaomatous polyps associated with peutz jegher's syndrome
Villous adenoma
Tubular adenomas
0a
single
.Juvenile Polyps * Commonest polyp of colorectum in infants and children. * Can cause intussusception, prolapse through rectum, bleeding. * Colonoscopic polypectomy is done. * Not a pre-malignant condition. ref:SRB&;s manual of surgery ,ed 3,pg no 831
Surgery
G.I.T
044e0f26-43e8-47f0-be46-af1feba96a44
Putrefaction is delayed in poisoning due to :
Carbolic acid
Organophosphorus
Lead
All
0a
multi
A i.e. Carbolic acid
Forensic Medicine
null
172c8e1c-73fb-472e-b0df-6f3f73812e0b
The pump responsible for gastric acid secretion is
H+ ATPase
Na+ - H+ ATPase
H+ - K+ ATPase
Ca2+ - H+ ATPase
2c
single
Gastric parietal cells are highly specialized for their unusual task of secreting concentrated acid. The cells are packed with mitochondria that supply energy to drive the apical H+,K+-ATPase, or proton pump, that moves H+ ions out of the parietal cell against a concentration gradient. The apical membrane also contains...
Physiology
Gastrointestinal System
24a3b80f-bc6a-415d-9c68-9ec9bc5f16d0
A 32 year old woamn with two live children was brought to emergency with the history of missed period for 15 dyas, spotting since 7 days and pain abdomen since 6hrs. Her pulse was 120/min, pallor ++, systolic BP BOmmHg. There was fullness and ternderness on per abdomen examination. Cu-T thread was seen through external...
Pelvic inflammatory disease
Missed aboriton with infectkion
Rupture ectopic pregnancy
Threatened aboriton
2c
multi
Rupture ectopic pregnancy
Gynaecology & Obstetrics
null
883c9a0b-8999-4a24-9d62-4dd82de7dced
A cardiologist asks for measurement of electromechanical systole (QS2) and left ventricular ejection time (LVET), and pre-ejection period (PEP). The cardiologist is informed by the technician that the carotid transducer is not functioning. Which of the following readings could not be obtained
QS2
QS2 and LVET
QS2 and PEP
LVET and PEP
3d
single
Electromechanical systole (QS2)- Time interval between the beginning of Q wave and beginning of the second heart sound. It requires ECG and phonocardiogram. Left ventricular ejection time (LVET)- Interval between the beginning of carotid pressure to the dicrotic notch. Requires carotid pulse tracing. Pre-ejection systo...
Physiology
null
16a0395d-6ea9-4dac-a0a4-7f77a8420e13
Treatment of chronic phase of CML is :
Imatinib
Hydroxyurea
Interferon
Cytarabine
0a
single
null
Pharmacology
null
5d062b83-d730-4f33-af80-478d28e8399d
Treatment of cord prolapse is based on all of the following factors, except:
Fetal viability
Fetal maturity
Fetal weight
Cervical dilatation
2c
multi
null
Gynaecology & Obstetrics
null
a1041e37-ff61-4353-85e5-fb472b6394f1
Pap smear is an example of -
Primary level of prevention
Secondary level of prevention
Teritary level of prevention
None of the above
1b
multi
Ans. is 'b' i.e., Secondary level of prevention o In secondary prevention, action halts the progress of a disease at its incipient stage and prevents complication. o Screening tests (e.g. - Pap smear), helps in diagnosis at early stage so that adequate treatment can halt disease progression and prevent complication.
Social & Preventive Medicine
null
e14969c5-2737-4e85-b64f-810baf670a94
All are true about sulphonyl ureas except?
It blocks ATP sensitive K+ channels and increase insulin release
They have higher risk of causing hypoglycemia than meglitinides
They are used mainly in type 1 DM
Chlorpropamide can cause dilutional hyponatremia
2c
multi
Sulphonyl ureas are mainly used in Type 2 DM because Type 1 DM is characterized by autoimmune destruction of β - cells of pancreas and atleast 30% of β - cells should be present for sulphonyl ureas to be effective.
Pharmacology
null
59ffaf86-997e-42e1-bfce-0e1397fd77d7
The usefulness of a ‘screening test’ in a community depends on its?
Sensitivity
Specificity
Reliability
Predicitive value
0a
single
Predictive value of a test signifies diagnostic power of the test. attribute of an idea screening test is its repeatability or reliability or reproducibility. Sensitivity has been defined as the ability of the test to identify correctly all those who have the disease, that is true positive (Hence determines the usefuln...
Unknown
null
cd5138c8-ed26-44bc-88cc-57875333639e
Differential white blood cell counts in the laboratory are useful in the diagnosis of:
Anemia
Eosinophilia
Vitamin deficiency
Spherocytosis
1b
single
null
Physiology
null
0d0d06fe-93fd-4600-94a1-0f3ccaf260bb
Which of the functions are TRUE regarding C-terminal domain of androgen receptor protein?
Ligand binding
Increasing biological half life
Increasing the affinity of receptor to DNA
Increasing the level of transcription
0a
multi
The androgen receptor proteins contain 3 common domains: 1- Highly conserved central domain that is responsible for DNA binding 2- N-terminal region that is involved in trascriptional activation, and 3- C-terminal domain that binds ligand Ref: Harper's Illustrated Biochemistry 27th Edition, Page 477; Molecular cell bio...
Biochemistry
null
81c61bcf-ef9b-4ef3-807f-1833fef8bed7
Riboflavin deficiency is assessed by
Transketolase
Glutathione reductase
PDH
None
1b
multi
Riboflavin deficiency is assessed by Glutathione reductase. The two biologically active forms are flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), formed by the transfer of an adenosine monophosphate moiety from ATP to FMN (Figure 28.15). FMN and FAD are each capable of reversibly accepting two hydrog...
Biochemistry
vitamins
ecd48525-260d-4e2d-9250-e5bd15ca7826
Investigation of choice to Determine Local Invasion in Esophageal Carcinoma(T staging) is?
Transabdominal Usg
CECT
Endpscopic USG
MRI
2c
single
Endoscopic Ultrasound - Determines Local Invasion In Esophageal Carcinoma(T staging).
Radiology
ULTRASOUND
b24a6686-d2a4-4d4b-8a3b-cbaad55e48d0
CCK-PZ causes all of the following except :
Gall bladder contraction
Pancreatic enzyme secretion
Increased gastrin secretion
Decreased lower esophageal sphinictor
2c
multi
C i.e. Increased gastrin secretion
Physiology
null
92736f6a-a3e7-41cb-b4dc-2e6edfb3f8da
The recommended size of endotracheal tube for 1 year old child is
2.5
3
4
5
2c
single
Tube diameter in mm = Age in years/4 + 4 = 1/4 + 4 = 17/4 = 4.2
Anaesthesia
null
b5994841-4c71-4a5c-8aa4-c7afa2b6fa2d
Parinaud's Syndrome is associated with all EXCEPT
Collier's sign may be present
Can be caused by hydrocephalus with acquiductal stenosis
Light near dissociation of pupil
Nuclear gaze palsy
3d
multi
(D) Nuclear gaze palsy # Parinaud's Syndrome or Dorsal Midbrain Syndrome and vertical gaze palsy, is an inability to move the eyes up or down. It is caused a tumor of the pineal gland which compresses the vertical gaze center at the rostral interstitial nucleus of medial longitudinal fasciculus (riMLF). The eyes lose t...
Medicine
Miscellaneous
55daa13d-b09c-4b71-a6b3-fbd608e7d861
Which of the following teeth have more than one occlusal form:
Maxillary 1st premolar
Maxillary 2nd premolar
Maxillary 1st molar
Mandibular 1st molar
2c
single
null
Dental
null
0c3b4814-6a05-45fd-a448-ebd3a2ed3dd8
While handling a febrile neutropenic patient all are essential except -
Repeated hand washing of hospital person
White cell infusion
Prophylactic antibiotic
Colony stimulating factor for macrophages
1b
multi
null
Medicine
null
abd07eca-4a1d-4741-bd1f-d97819cc4959
Ring scotoma is seen in: September 2012
Glaucoma
Retinitis pigmentosa
Sympathetic ophthalmia
Vitreous hemorrhage
1b
single
Ans. B i.e. Retinitis pigmentosa
Ophthalmology
null
a209cab2-17fa-4ce5-81f7-8374016623d6
Rigor mois occurs first in which voluntary muscle: Delhi 06, 07; COMEDK 08; SGPGI 11
Muscles of eyelids
Small muscles of hands
Neck muscles
Face muscles
0a
multi
Ans. Muscles of eyelids
Forensic Medicine
null
f6331671-e816-44a1-9437-4cf01e33783f
A patient suddenly experienced pain radiating along the medial border of the dorsum of foot. Which of the following nerve is most likely to be involved?
Sural nerve
Saphenous nerve
Deep peroneal nerve
Superficial peroneal nerve
1b
single
Since the patient is having pain along the medial border of dorsum of foot, he is most likely suffering from an injury to saphenous nerve. Saphenous nerve is the terminal sensory branch of femoral nerve. It provides sensory innervations to the medial region of the heel, medial malleolus, medial border of foot as far as...
Surgery
null
a02059d8-4bc0-4901-a623-afbae21fd98f
The factor which promotes virulence of M. tuberculosis ?
Wax D
Cord factor
Muramyl dipeptide
Muramyl dipeptide
1b
single
Ans. is 'b' i.e., Cord factor Virulence factors . Virulent strains of tubercle bacilli form microscopic "serpentine cord" in which acid fast bacilli are arranged in parallel chains, cord formation is correlated with virulence. A "cord factor" has been extracted from virulent bacilli with pateroleum ether. It inhibits m...
Microbiology
null
895ed723-4ea7-4f40-812f-d69b4ca8e0ca
Which of the following is consistent with diagnosis of De-Quervain thyroiditis?
45 year female with 2 week history of painful thyroid gland with elevated T4, T3 and low TSH. RAIU shows increased uptake
25 year female with painless enlarged thyroid with elevated T4,T3 and undetectable TSH. RAIU shows increased uptake
45 year female with fatigue and low T4, T3 and Low TSH
45 year male with painful thyroid 8 weeks ago with low free T4, T3 and elevated TSH
3d
single
De Quervain thyroiditis is characterised by fever, constitutional symptoms and painful enlarged thyroid due to viral etiology. Initially T4 and T3 are elevated due to damage to follicles. RAIU uptake is reduced. Subsequently hypothyroid phase sets in and RAIU becomes normal. Option A is wrong due to increased RAIU upta...
Medicine
Diseases of Thyroid
3d096d5f-f236-4638-b89c-16c59ccfde7e
Peripheral blood smear examination of a post splenectomy patient would show the presence of:
Dohle bodies
Hypersegmented neutrophils
Spherocytes
Howell-Jolly bodies
3d
single
In the absence of a functional spleen, nuclear remnants are not culled from the red cells and remain as small homogeneously staining blue inclusions, known as Howell-Jolly bodies. Dohle bodies are light blue-gray, oval, inclusions located in the peripheral cytoplasm of neutrophils seen in infections, burns physical tru...
Pathology
null
b3d9f7c0-1f61-44d2-ab2c-4ecb8925ad05
Toxicity of local anaesthesia is reversed by :
IV epinephrine
IV nalorphine
IV Barbiturates
IV sodium bicarbonate
2c
single
null
Surgery
null
478f8fe7-b710-4f04-8a6d-b8bb746a0eb0
Which is the most common micro-organism known to cause tropical pyomisitis?
Streptococcus viridans
Staphylococcus albus
Klebsiella pneumoniae
Staphylococcus aureus
3d
single
Tropical pyomyositis, a disease often seen in tropical countries, is characterised by suppuration within skeletal muscles, manifesting as single or multiple abscesses. The most common organism implicated is Staphylococcus aureus. In 20%-50% of cases there is a history of trauma to the affected muscles. Commonly involve...
Microbiology
Misc.
aac92220-8896-4a63-976b-458e2b5bcf12
A temporary, provisional view held by the people on a point of view is -
Opinion
Practice
Attitude
Belief
0a
single
- opinions are views held by people on a point of dispute. - they are based on the evidence available at a time Reference : Park's textbook of preventive and social medicine, 25th edition, pg no:732 <\p>
Social & Preventive Medicine
Social science, Mental health & Genetics
b481645e-1103-4e29-b328-7c0af584247f
Drug of choice for treatment of neurocysticercosis is:-
Pyrantel palmoate
Praziquantel
Albendazole
Ivermectin
2c
single
Both praziquantal and albendazole are effective against neurocysticercosis. Albendazole is preferred because of its more efficacy and lesser duration of treatment
Pharmacology
Anti-Parasitic Drugs
901a76cc-d9ef-4fcb-961a-3978ede1e74d
Adrenal insufficiency causes: March 2011
A rise in plasma sodium/potassium ratio
Low blood pressure
Increase breakdown of protein
All
1b
multi
Ans. B: Low blood pressure Features of an acute adrenal crisis include circulatory shock with severe hypotension, hyponatremia, hyperkalemia and, in some instances hypoglycemia and hypercalcemia.
Medicine
null
d6e56f6f-f526-4484-93b1-168c5e9ec2b6
The commonest cause of Intracerebral Bleed is:
Thrombocytopenia
Diabetes
Hypeension
Berry aneurysm
2c
single
Answer is C (Hypeension): An intracerebral bleed (parenchymal) invariably results from rupture of small perforating aeries or aerioles as a result of Hypeension.
Medicine
null
c76d4d4a-2bd4-4369-ba27-74ccb961fc31
Following is the most important factor in the management of shock:
Blood pressure
Cardiac output
CVP to 8 cm of water
Deficiency of effective circulating blood volume
3d
single
null
Pathology
null
070129f2-755f-4b28-a046-dbb7367a13c2
For the prevention of human rabies, immediate flushing and washing the wound(s) in animal bite cases, with plenty of soap and water, under running tap should be carried out for how much time
2 minutes
1 minute
15 minutes
5 minutes
2c
single
Local wound Treatment in Rabies Purpose of local treatment is to remove as much virus as possible, from site of inoculation, before it is absorbed on local nerve endings Local wound treatment can reduce chances of rabies upto 80% Immediate flushing and washing wound area with plenty of soap and running water for minimu...
Social & Preventive Medicine
Communicable diseases
1b71a00e-2c7b-47af-9e2e-dabab0ddd943
During the ear examination, cough occurs due to stimulation of?
Vagus
Trigeminal
Hypoglossal
Trochlear
0a
single
Arnold nerve. It is an auricular branch of the jugular ganglion of the vagus. It supplies the skin of posterior pa of pinna on the medial surface of the concha, and posterior wall of the external auditory canal and tympanic membrane. The auricular nerve is the afferent limb of the Ear-Cough or Arnold Reflex. Ref: Dhing...
ENT
Ear
f9c47044-8956-4a24-98cc-27e334c2acf3
Which of the following is not a radiological feature of meningioma?
Lamellar calcification
Enlarged foramen spinosum
Increased meningeal vascular markings
Decalcification inner table
3d
single
Ans. Decalcification inner table
Radiology
null
6e3007c9-afa1-420c-8625-86c74ea55a25
Gall bladder stone formation in influenced by all except:
Clofibrate therapy
Hyperalimentation
Primary biliary cirrhosis
Hypercholesterolemia
3d
multi
Answer is D (Hypercholesterolemia): It is increased concentration of cholesterol relative to bile salts in bile that promotes gall stone formation. Serum cholesterol may well be normal. All ether options are known local factors that promote gall stone formation and hence Hypercholesterolemia is the single best answer o...
Medicine
null
21b7dd5c-97e4-41d1-9208-f9a2da5d18fe
The failure of a calcium hydroxide pulpotomy done on a primary 1st molar is due to:
Internal resorption
External resorption
Pulp calcification
Pulp fibrosis
0a
single
null
Dental
null
e274527b-3b94-41c0-8bf4-1ca94cc26054
First antiboy to appear in hepatitis:
IgM anti HBe
IgM anti HBc
IgG anti HBe
IgM anti HBs
1b
single
Ans. b. IgM anti HBc
Microbiology
null
f4c96f85-cd54-4a09-b11e-2405d4cee275
All of the following affect resting ventilation except
Stretch receptors
J receptor
Oxygen
PCO2
1b
multi
B i.e. J receptorTidal volume excessive load is prevented by (or lung maintains the tidal volume by) activation of slowly adapting pulmonary (or bronchial) stretch receptorsQ."Inflation of lungs induces fuher inflation" due to elastic recoil of alveoli. With inflation of the lungs, there is augmentation of respiratory ...
Physiology
null
a0a49f3a-6744-48ff-9661-0ecd2dcd6305
A 22-year-old woman consults you for treatment of hirsutism. She is obese and has facial acne and hirsutism on her face and periareolar regions and a male escutcheon. Serum LH level is 35 mIU/mL and FSH is 9 mIU/mL. Androstenedione and testosterone levels are mildly elevated, but serum DHAS is normal. The patient does ...
Oral contraceptives
Corticosteroids
GnRH
Parlodel
0a
single
This patient has polycystic ovarian syndrome (PCOS), diagnosed by the clinical picture, abnormally high LH-to-FSH ratio (which should normally be approximately 1:1), and elevated androgen but normal DHAS. DHAS is a marker of adrenal androgen production; when normal, it essentially excludes adrenal sources of hyperandro...
Gynaecology & Obstetrics
Physiology & Histology
9822ee4f-fad4-4533-b971-793a1a7ce4dc
When undertaking bleaching of vital teeth of the following are done except:
Prophylaxis
Use of protective eye glasses
Use of local anaesthesia
Polishing after treatment
2c
multi
null
Dental
null
15e4a3b8-d8b8-4683-b31c-89ac1585e9dc
The composition of ORS recommended by WHO is
3.5 g NaCl
4.5 g NaCl
2.9 g sodium-potassium citrate
2.8 g sodium bicarbonate
2c
single
null
Social & Preventive Medicine
null
07266217-abc8-4533-9cf7-4c855242f945
Inversion of nipple occurs due to the involvement of
Breast lobules
Montogomory tubercles
Cooper ligament
Lactiferous ducts
3d
single
Breast carcinoma arising from lactiferous ducts is called as ductal carcinoma. Breast carcinoma arising from lobules is called as lobular carcinoma. It is 10% common. Cutaneous Manifestations of Carcinoma Breast Peau d’orange: Due to obstruction of dermal lymphatics, openings of the sebaceous glands and hair follicl...
Surgery
null
0d2a2bc9-ec3d-4e06-b579-406415e2d635
The principle that in spinal cord, the dorsal roots are sensory and the ventral roots are motor, is known as:
Bell-Magendie law
Dale's principle
Monro-Kellie hypothesis
Muller's doctrine
0a
single
Bell Megendie Law: States that in spinal cord, the dorsal roots are sensory and the ventral roots are motor. Dale's principle: Same neurotransmitter is released at all branches of a neuron. Monro Kellie hypothesis: The blood volume in the cranial cavity is approximately constant. As the cranium is rigid (except in a yo...
Physiology
Sensory System
0084aa06-8b00-4ccb-93ef-6df696b750b8
A 60 year old man who is a known case of coronary artery disease with drug eluting stent placed 1year ago, presents with lump in abdomen and is posted for laparoscopic diagnostic evaluation. He is also hypertensive patient. Which of the following medications should he discontinue prior to procedure
Atenolol
Clopidogrel
Simvastatin
Aspirin
1b
single
Clopidogrel has to be stopped 7 days prior to surgery.
Anaesthesia
null
b77be92c-10d8-47e2-907c-a633e1ec616f
Impoant step in activation of naive CD 4+ T cells and initiation of cell mediated immune response is played by Interleukin?
1
2
3
4
1b
multi
Ans. is 'b' i.e., 2 Activation of CD4+ T Cells: Naive CD4+ T cells recognize peptides displayed by dendritic cells and secrete IL-2, which functions as an autocrine growth factor to stimulate proliferation of the antigen- responsive T cells. The subsequent differentiation of antigen-stimulated T cells to TH1 or TH17 ce...
Pathology
null
c5103336-0668-44b5-911c-ef4b35e8feaf
A 60-years-old man with diabetes mellitus presents with painless, swollen right ankle joint. Radiographs of the ankle shows destroyed joint with large no. Of loose bodies. The most probable diagnosis is:
Charcot's joint
Clutton's joint
Osteoahritis
Rheumatoid ahritis
0a
single
Patient of diabetes with painless swollen joint is enough for the diagnosis of charcot's joint. X-Ray Features Marked destructive changes with periaicular erosions Joint space narrowing Osteophyte formation Subchondral sclerosis Loose bodies. The changes simulate osteoahritis, but the absence of pain is diagnostic. Sim...
Orthopaedics
Joint disorders
4561777c-bd6b-46bf-961f-d4ac5ba3f141
Death of the mother from an automobile accident comes under
Direct maternal death
Indirect maternal death
Nonmaternal death
None of the above
2c
multi
Nonmaternal death: Death of the mother that results from accidental or incidental causes not related to pregnancy. An example is death from an automobile accident or concurrent malignancy(Ref: William's Obstetrics; 25th edition)
Gynaecology & Obstetrics
All India exam
cecfa7c5-8084-4091-816d-ed9b62203e4e
Anti–TNF alpha drugs are used for the treatment of all of following diseases EXCEPT :
Systemic lupus erythematosis
Seronegative arthritis
Psoriatic arthritis
Crohn's disease
0a
multi
There is already under-expression of TNF-α in SLE, therefore we cannot use anti-TNF drugs for this condition. It is further strengthened by the fact that anti-TNF alpha drugs like infliximab cause SLE as the adverse effect. Indications for TNF-α inhibitors Rheumatoid arthritis Juvenile arthritis Psoriatic arthritis Ps...
Pharmacology
null
b198555f-572c-4426-a967-a48fc417e5a0
The rate of cooling down of dead bodies in tropical climate is: Delhi 06; Kerala 06; UP 07
0.2degC/h
0.5degC/h
1.5degC/h
2degC/h
1b
single
Ans. 0.5degC/h
Forensic Medicine
null
8f88ef31-b8a5-45c7-94c2-6822c26d8b39
A 73-year-old man has ischemic rest pain of the left calf. Workup reveals occlusion of the left superficial femoral artery. He is scheduled for an elective femoral-popliteal bypass. A good way to reduce the risk of infection would be to:
Irrigate the wound with bacitracin during the operation
Start cefazolin 1 gIV 4 hours before the surgery
Use a plastic adherent drape
Not shave the leg
3d
single
Shaving is associated with an increased incidence of wound infection compared to the use of electric clippers or depilatories, as well as compared to no hair removal at all. Prophylactic antibiotics should be started within 60 minutes of the incision time. Plastic adherent drapes and antibiotic wound irrigation have no...
Surgery
Miscellaneous
9ebea45d-3d4c-43d6-8712-3165037dd534
A pregnant woman with fibroid uterus develops acute pain in abdomen with low grade fever and mild leucocytosis at 28 weeks. The most likely diagnosis is:
Preterm labour
Torsion of fibroid
Red degeneration of fibroid
Infection in Fibroid
2c
single
Red degeneration This complication occurs during pregnancy (2nd trimester) Myoma becomes tense and tender Symptoms: Abdominal pain, constitutional upset and fever Rx :bed rest and analgesics. Never operate In case of torsion of fibroid, severe abdominal pain is there but fever and raised leucocyte count is not seen. Fi...
Gynaecology & Obstetrics
Fibroids
fbd853be-310f-4e62-96b5-dddcb8cee4b2
Classification of aoic dissection depends upon?
Cause of dissection
Level of aoa affected
Percentage of aoa affected
None
1b
multi
Ans. is 'b' i.e., Level of aoa affectedClassification of Aoic dissectiono The risk and nature of serious complications of dissection depend strongly on the level of aoa affected, with the most serious complications occuring from the aoic valve to the arch.o Thus aoic dissections are generally classified into two types ...
Pathology
null
c92fe108-a70a-40ba-a0b1-705115a411d0
A child having IQ of 25 falls in which category?
Educable
Trainable
Dependent
Needs life support
2c
multi
ANSWER: (C) DependentREF: Shorter Oxford Textbook of Psychiatry 5th edition p. 708-712, Current Diagnosis & Treatment in Psychiatry p. 543CLASSIFICATION OF MENTAL RETARDATION: Mild MRModerate MRSevere MRProfound MRIQ50-7035-5020-35<20Quality of lifeEducableTrainableDependentNeeds life supportProgressClass 6Class 2--
Pediatrics
Neurologic Evaluation
1974768c-77ac-41b4-8897-eec835d8c3ff
The symptoms of dietary deficiency of niacin (which results in pellagra) will be less severe if the diet has a high content of:
Tryptophan
Tyrosine
Thymine
Thiamine
0a
single
a. Tryptophan(Ref: Nelson's 20/e p 325, Ghai 8/e p 118)Tryptophan can be converted to nicotinamide adenine dinucleotide (NAD) 60mg tryptophan gives rise to 1mg niacin.
Pediatrics
Nutrition
485305c9-fc36-42a2-ab04-94e696601d86
Blood supply of posterior limb of internal capsule includes all except-
Middle cerebral artery
Anterior cerebral artery
Anterior choroidal artery
Posterior cerebral artery
1b
multi
Posterior limb of internal capsule is supplied by three sets of arteries : striate branch of middle cerebral  artery, anterior choroid artery; and posterolateral branches of posterior cerebral artery.
Anatomy
null
3b9e48ec-21a1-4b0c-91f9-9ee375381ffe
Blood vessels can be harvested from a body for the purpose of transplantation latest by what period after death?
8 hours
12 hours
48 hours
72 hours
3d
single
The periods within which some organs should be removed are as follows Cornea - 6 hours Skin - 24 hours Bone - 48 hours Blood vessels - 72 hours Ref: Essentials of forensic medicine and toxicology by Narayan reddy, edition 21, page 112
Forensic Medicine
null
76f9d27a-bfbc-4491-911f-bdf406db3e53
According to 357 (c) CrPC, all hospitals (Govt or private) shell provide the first aid medical care free of cost to victims of offences covered by the following section except:
326 A IPC
376 IPC
302 IPC
376 A IPC
2c
multi
C. 302 Treatment of victims : * All hospitals, public or private, whether run by the Central Government, the State Government, local bodies or any other person, shall immediately, provide the first-aid or medical treatment, free of cost, to the victims of any offence covered under section 326A, 376, 376A, 376B, 376C, 3...
Forensic Medicine
Sexual offences
a8b586ea-206b-4212-8995-9c243da81597
In a chronic smoker, a highly malignant aggressive and metastatic lung carcinoma is :
Squamous cell Carcinoma
Adenocarcinoma
Large cell carcinoma
Small cell Carcinoma
3d
multi
Cigarette smoking is most strongly associated with squamous Cell Ca and small cell Ca and less commonly associated with Adenocarcinoma. But small cell Ca is highly malignant & Blood stream metastasis occurs early in the course of this Ca.So the answer is small cell carcinoma.  Also Remember M.C Variety of lung Ca in In...
Medicine
null
15602abf-3f96-4c57-9307-12667465300d
Hypersensitivity vasculitis affects -
Post-capillary venules
Arterioles
Veins
Medium-sized arteries
0a
single
null
Medicine
null
5b94e95b-5d3c-4f56-97d7-efbf27c7f37a
Which of the following is a prodrug is -
Phenytoin
Carbamazepine
Primidone
Valproic acid
2c
single
(C) (Primidone) (38 - H 18th) (23, 413 - KDT 7th)PRIMIDONE - A deoxybarbiturate converted by liver to phenobarbitone and phenylethyl malonamide (PEMA). Its antiepileptic activity is mainly due to those active metabolites because t 1/2 of primidone (6-14 hr.) is less than that of its active metabolites, About 1/3 primid...
Pharmacology
General Pharmacology
62bbda75-f770-4740-8d7f-5bc8a164acc3
The following are examples of apoptosis, except
Menstrual cycle
Tumour necrosis
Graft versus host disease
Pathological atrophy following duct obstruction
1b
multi
NecrosisApoptosisAlways pathological Maybe physiological or pathological Associated with disruption of cellular homeostasis Impoant for development, homeostasis & elimination of pathogens & tumour cellsAffects contiguous group of cellsAffects single cellCell size increased Cell size shrunken Passive Active Cause inflam...
Anatomy
All India exam
f49a8772-f8de-41ae-bd9a-101ef8f9e716
Which of the following antifungal agents binds to ergosterol
Flucytosine
Terbinafine
Amphotericin B
Fluconazole
2c
single
POLYENE ANTIBIOTICS Amphotericin B (AMB) Mech of action:- The polyenes have high affinity for ergosterol present in fungal cell membrane. They combine with it, get inseed into the membrane and several polyene molecules together orient themselves in such a way as to form a 'micropore'. The hydrophilic side forms the int...
Pharmacology
Antibiotics
945aef4d-9873-461e-80f8-866581bd6a66
After digestion by restriction endonucleases DNA bands can re-joined by which of the following substance?
DNA polymerase
DNA ligase
DNA topoisomerase
DNA gyrase
1b
single
DNA ligase is used to join the DNA bands formed after digestion by restriction endonuclease. DNA gyrase: Its a special type of topoisomerase, has the unusual propey of being able to introduce negative supercoils into resting DNA. This facilitates the future replication of DNA because the negative supercoils neutralise ...
Biochemistry
null
b0b74d21-ea72-4b47-a0c4-c691fe45567f
Abnormalities of copper metabolism are implicated in the pathogenesis of all the following ExceptEXPL
Wilson's disease
Menkes Kinky-hair syndrome
Indian childhood cirrhosis
Keshan disease
3d
multi
(Refer: Nelson's Textbook of Pediatrics, SAE, 1st edition, pg no. 344)
Pediatrics
All India exam
28a4b7ba-cccf-4d2d-8a96-d0dd09cba045
Carcinoma in situ of skin is called as:
Cowden syndrome.
Bowen disease.
Both
None
1b
multi
null
Pathology
null
c532d362-8ba4-4ad3-918d-2d924b10c55d
All the following pathogenic bacteria fulfill Kochs postulates except
Treponema pallidum
Yersinia pestis
Bacillus anthracis
Helicobacter pylori
0a
multi
Koch's postulates: A microorganism was accepted as the causative agent of infectious disease, only when it satisfied all the following criteria: 1. The microorganism must be present in every case of the disease but absent from healthy host. 2. The suspected microorganism must be isolated and grown in a pure culture fro...
Microbiology
General Microbiology Pa 1 (History, Microscopy, Stains and Structure and Physiology of Bacteria)
9ce6e8cc-ca13-4ef2-bfbd-ac063cf227bf
Levinthal Coles Lillie bodies are seen in -
LGV
Psittacosis
KalaAzar
Chicken pox
1b
single
Ans. is 'b' i.e., Psittacosis * In psittacosis infected cells, including alveolar macrophages from patients, and mouse brain, yolk sac and cell cultures shows inclusion bodies - Levinthal - Cole - Lillie (LCL) bodies.
Microbiology
Virology
da06f0a5-5292-496f-80b4-78f16955d295
Low grade squamous Intraepithelial leison of cervix in Bethseda system includes :
CIN 1
CIN 2
CIN 3
Squamous metaplasia
0a
single
Dysplasias are graded as: 1. Mild dysplasia (CIN-I). The undifferentiated cells are confined to the lower one-third of the epithelium. The cells are more differentiated towards the surface. Mild dysplasia due to infection is often seen in young women indulging in sexual activity. CIN-I is lately described as low grade ...
Gynaecology & Obstetrics
Gynaecological oncology
9ddd350b-7074-40ab-bab7-f0003984ad1e
Which of the following fracture is known as "fracture a-la signature"?
A depressed fracture
A fissured fracture
Separation of the suture
A ring fracture
0a
single
Depressed fractures are produced by local deformation of the skull. In this, fractured bone is driven inwards into the skull cavity. The outer table is driven into the diploe, the inner table is fractured irregularly and to a greater extent and may be comminuted. They are also called 'fractures a la signature' (signatu...
Forensic Medicine
null
26060999-5f56-4a34-84be-0f8e1ae7f56e
Which of the following is a terminal axillary lymph node?
central
lateral
anterior
apical
3d
single
Apical group of lymph nodes are the terminal axillary lymph nodes. Lymphatic drainage of axillary lymph nodes Anterior, posterior, lateral - central - apical - infra clavicular - supraclavicular - right jugular trunk - right lymphatic duct - right jugulo subclan venous angle
Anatomy
Upper limb : Miscellaneous
5395f0d5-df5f-4d5d-bfa7-94bbab8621bd
All of the following are ture regarding cephalosporins except -
Bactericidal agents
Active against only gram negative bacteria
IIIrd generation are resistant to beta-lactamases from gram negative bacteria
Ceftriaxone is administered parenterally
1b
multi
Ans. is 'b' i.e., Active against olny gram negative bacteria Cephalosporins are active against gram positive as well as gram negative bacteria, and are bactericidal. o Ceftriaxone is a parentral cephalosporin. o Third generation cephalosporins are highly resistant to beta-lactamases from gram negative bacteria.
Pharmacology
null
ce207c6c-d13c-40df-8e90-ed857aebb3a4
A 30-year-old female presents with a 3-month history of 10kg weight loss despite an increased appetite. She also complains of anxiety, diarrhea and amenorrhea. Examination reveals a fine tremor, brisk reflexes and a systolic murmur heard throughout the precordium. A urine pregnancy screen was negative. What is the most...
Pulsus paradoxus
Collapsing pulse
Irregularly irregular pulse
Pulsus alternans
2c
single
Female, weight loss in spite of appetite, amenorrhea, tremors, brisk reflexes are features of Thyrotoxicosis Option A- Pulses Paradoxus is feature of C. Tamponade it is ruled out Option B- Collapsing pulse- Rapidly rising pulse, which collapses suddenly as aerial pressure falls rapidly, during late systole and diastole...
Medicine
Murmurs
db35fe68-a1ca-4186-8913-9b4efb4da43c
Advantage of cisatracurium over atracurium is?
Short duration of action
Rapid onset
Less allergic
Releases less histamine
3d
multi
Ans. (D) Releases less histamine(Ref: Goodman and Gilman 13th/e p182)Both atracurium and cis-atracurium are non-depolarizing neuromuscular blockers.Both of these are intermediate acting agents (both have same duration of action).Both of these agents are cardiostableAtracurium has faster onset of action as compared to c...
Pharmacology
Anaesthesia
e91962cc-3d50-407d-8209-efae81c174c5
The initiation of hemoglobin synthesis requires:
Histidine
Glycine
Folate
Iron
1b
single
Ans. (b) GlycineRef: Harper's Biochemistry, 30th ed. pg. 326-28* Heme is synthesized in a complex series of steps involving enzymes in the mitochondrion and in the cytosol of the cell* The first step in heme synthesis takes place in the mitochondrion. Steps in heme synthesis are:# Condensation of succinyl CoA and glyci...
Biochemistry
Proteins and Amino Acids