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ff07ae5b-c4aa-4894-a0c0-e0fa73d473ff | GLUT-5 is tra nsporter for - | Glucose | Fructose | Mannose | Galactose | 1b | single | Ans. is 'b' i.e., Fructose o GLUT-5 is a transporter for fructose. FunctionMajor sites of expressionSecondary active transport(Na+-glucose cotransport) o SGLT1Absorption of glucoseSmall intestine, renal tubuleso SGLT 2QAbsorption of glucoseRenal tubules QFacilitated diffusionoGLUT1Basal glucose uptakePlacenta, Blood-br... | Biochemistry | Chemistry of Carbohydrates, Amino sugars, and Mucopolysaccharides |
ff9f0fb7-ff7a-4c45-9cf2-ded152c42369 | Which of the following statements about the Narcotic Drugs and Psychotropic Substances ACT (NDPS ) is true: | Provides severe punishment for drug users and drug peddlers alike | Recommends treatment / rehabilitation of drug users and punishment for drug peddlers | Recommends treatment / rehabilitation of drug users and punishment for drug peddlers | Farmers growing opium are permitted to grow and consume unlimited amounts of opium | 1b | multi | B i.e. Recommends treatment/ rehabilitation of drug users and punishment for drug peddlers Alcohol is not included in NDPS Act, which regulates and prohibits all activities (from cultivation to consumption) of narcotic drugs & psychotropic substances except for medicinal & scientific purpose. An amendment has diluted &... | Forensic Medicine | null |
e57a6936-7172-4b6d-85a4-ca2bb6f9a18a | Which of the following is the donor of ADP-ribose for ADP-ribosylation reactions? | Adenosine triphosphate | Adenosine monophosphate | Nicotinamide adenine dinucleotide | Flavin mononucleotide | 2c | single | ADP-ribosylation One of the histone post-translational modifications. NAD+ acts as the source of ADP-ribose. Eg : Mechanism of action of cholera toxin, diphtheria toxin and ricin | Biochemistry | Translation |
f0ced2d3-9ca8-4d79-9863-61b71e994c06 | Natural killer cell is: | MHC restricted | Antibody dependent | Null cells | B-lymphocytes | 2c | single | Ans. c. Null cells | Microbiology | null |
0aac2fe0-45a3-48f7-9553-44c5f8e30dcb | Hypersplenism is associated with- | Pancytopenia | Thrombocytopenia | Leukopenia | Polycythemia | 0a | single | null | Surgery | null |
e1ac3c64-33bb-4d92-96fa-8c055de6238c | What is the effect of 1-2 MAC dose of volatile anaesthetic agents on EEG waveforms- | b-a-th-S | S-th-a-b | b -th-S- a | a - th-S- b | 0a | single | EEGs recorded on the scalp can be processed to quantify the amount of activity in each of four frequency bands: Delta (o to 3hz), Theta (4 to 7 Hz) alpha (8 to 13 Hz), Beta (> 13 Hz) Between 1-2 MAC shift is towards decreased frequency. b-a-th-S | Anaesthesia | Inhalational Anesthetic Agents |
6bfffe9f-8117-41d7-b262-a466c6e55d9a | Claustrophobia means | Fear of heights | Fear of lizards | Fear of closed spaces | Fear of open spaces | 2c | single | Claustrophobia refers to irrational fear of closed spaces. | Psychiatry | null |
2c0b52d5-b74a-4e8d-9c7f-5d9634adf7c2 | Which of the following is not an injectable molded ceramic: | IPS Empress. | IPS Empress 2. | Dicor. | None. | 2c | multi | Dicor is castable ceramic. | Dental | null |
659b7e25-3b78-40e4-a616-8683c6600812 | Which of the following actions are caused by 2-4-diinitrophenol? | Inhibition of ATP synthase | Inhibition of electron transpo | Uncoupling of oxidation and phosphorylation | Accumulation of ATP | 2c | single | 2,4-dinitrophenol and valinomycin are two uncouplers which inhibit oxidative phosphorylation. 2,4-dinitrophenol is a potent uncoupler even in low concentrations by dissolving itself in the bi-lipid core of the inner cell membrane. Ref: Harper's Illustrated Biochemistry 27th/107; Biochemistry 3E By S C Rastogi, 2010, Pa... | Biochemistry | null |
b464a8bd-60b9-41a0-9097-58560033a0f3 | Most common delusions seen in schizophrenia are | Delusions of erotomania | Delusions of persecution | Delusions of grandiosity | Delusions of infidelity | 1b | single | Delusions of persecution are most common delusions in schizophrenia Bizarre delusions may also be seen in schizophrenia Ref: Essentials of postgraduate psychiatry By JN Vyas 1st ed Pg 398 | Psychiatry | Schizophrenia and other psychotic disorders |
866cb662-c8b4-4881-ace6-ab4e3f5e8fe8 | A women consumes several tablets of amitryptiline leading to poisoning. All of the following can be done except | Sodium bicarbonate infusion | Gastric lavage | Diazepam to control seizure | Atropine as antidote | 3d | multi | D i.e. Atropine as antidote | Forensic Medicine | null |
3a637895-5adf-4aa5-ae52-2ebc2bbfd0fd | In Jorgensen technique on IV sedation for dental procedure drugs used are | Pentobarbital | Mepiridine | Scopalamine | All the above | 3d | multi | null | Surgery | null |
60b94a07-2d2a-4c34-9ff4-7e36a2afee5f | What is true about antemortem wound? | No staining left after washing | No gaping | Uncoagulated blood | Arterial bleed | 3d | multi | Hemorrhage in the antemortem wound is arterial.
Stain remains after wash (staining cannot be washed) in the antemortem wound.
Gaping is seen and blood is clotted in the antemortem wound. | Forensic Medicine | null |
dbd26ca9-bee1-41c6-934f-f2987202e666 | In noise induced hearing loss , audiogram shows a Boiler's notch at ? | 1000 Hz | 2000 Hz | 3000 Hz | 4000 Hz | 3d | single | Noise induced hearing loss Boiler notch at 4000 HZ Max seen at 3000 - 6000 HZ Sterocilia of outer hair cells are 1st to be affected . Carha's notch - dip is present at 2000 HZ .(seen in otosclerosis) | ENT | Otosclerosis |
28f37338-99cf-49a0-b24d-270a988ae09a | Chemoattractant is - | C5a | C1 | C3 | C2 | 0a | single | - the transmigration of leucocytes after crossing several barriers to reach the interstitial tissue is a chemotactic factor mediated process called chemotaxis. - C5a and C3a are anaphylatoxins and powerful chemoattractant. Reference : Harsh mohan text book of pathology, 7 th edition,Pg no:120 <\p> | Microbiology | Immunology |
d62fde17-ec4b-4dd1-98b3-983663e5ea82 | All of the following are increased in infants of hea disease patient except | Prematurity | IUGR | Increased incidence of cardiac disease | Neural tube defect | 3d | multi | Fetal effects in Cardiac disease complicating pregnancy Overall Perinatal moality is not greater than general population accounts for 45% Fetal Growth Restriction Preterm labor If mother has congenital hea disease fetus is at risk 50% have same anomaly as mother Reference: William's Obstetrics; 24th edition; chapter 49 | Gynaecology & Obstetrics | Medical, surgical and gynaecological illness complicating pregnancy |
0715e009-b149-49de-bf3d-aa630a87f605 | Which premolar would be the most likely to have a single pulp horn? | Maxillary first. | Mandibular first. | Mandibular second. | Maxillary second. | 1b | single | Mandibular first premolar is most likely to have a single pulp horn | Dental | null |
a8a006be-9d15-4e1d-8175-226aa3cde38a | A 26-year-old primigravid woman at 42 weeks' gestation comes to the labor and delivery ward for induction of labor. The prenatal course was significant for a positive group B Streptococcus culture performed at 35 weeks. Antenatal testing over the past 2 weeks has been unremarkable. The patient is staed on lactated Ring... | Infection | IV fluids | Postdates pregnancy | Prostaglandin (PGE2) gel | 3d | multi | Prostaglandin (PGE2) gel is widely used for labor induction. In simple terms, it is used "to soften" an unorable cervix, to make the cervix more orable for induction. It has been shown to lead to an improvement in the Bishop's score, a shoer duration of labor, and deliveries. PGE2 gel can also cause uterine contraction... | Gynaecology & Obstetrics | null |
00891abc-8b2f-441d-8449-6d73cb3b018f | Basanti 23 years old pregnant woman (First trimester) presents with features of dilated cardiomyopathy. Which of the following drugs you will NOT give to treat her: | Digoxin | ACE inhibitors | Diuretics | Vasodilators | 1b | single | ACE inhibitors CONTRAINDICATION OF ACE INHIBITORS Bilateral renal aery stenosis, Single kidney, Pregnancy , Hyperkalemia | Surgery | null |
c59ae0e3-1f6a-45d1-9758-c66881fb88b4 | ABO blood groups inheritance is an example of - | Mitochondrial inheritance | Allelic exclusion | Sex-linked inheritance | Co-dominance | 3d | multi | . Co-dominance | Pathology | null |
b072d692-96f6-4474-b89d-6c4dc00a87aa | A child presents with white lesion (depigmented macule ) of 2x 2 cm with irregular margin over forehead and glabella. There is white forelock over forehead since birth. Diagnosis is: | Piebaldism | Dermatitis | Vitiligo | Nevus of Ito | 0a | single | Ans. a. PiebaldismWhite forelocks are also seen associated with warden burg syndrome | Skin | Skin Lesions And Disorders Of Pigmentation |
99adecc7-1dab-4808-84bd-a4b4d24dd7e3 | Deformity associated with ulnar nerve injury is: | Wrist drop | Simon hand | Claw hand | Ape thumb deformity | 2c | single | Ans:C.)Claw Hand. An ulnar claw, also known as claw hand, or 'Spinster's Claw' is an abnormal hand position that develops due to a problem with the ulnar nerve. A hand in ulnar claw position will have the 4th and 5th fingers extended at the metacarpophalangeal joints and flexed at the interphalangeal joints. The patien... | Anatomy | null |
e1fffcd9-6095-4efc-9cca-2a8235fb0a76 | All of the following may lead to corneal opacity in newborn except – | Endothelial dystrophy | Sclerocornea | Mucopolysaccharidosis | Droplet keratopathy | 3d | multi | Causes of congenital opacities of cornea (STUMPED classification) :-
Sclerocornea; Tear in descmet's membrane (Congenital glaucoma, birth trauma); ulcer (HSV, bacteria); metabolic (Mucopolysaccharidosis, mucolipidosis, Tyrosinosis); Posterior corneal defect (Peter's anomaly, posterior keratoconus, staphyloma); Endothel... | Ophthalmology | null |
af139054-293e-4002-96ff-58fd30e49637 | For assessing new disease with no etiological hypothesis which is the best study | Cohort study | Case control study | Randomised control trial | Descriptive epidemiology | 3d | single | null | Social & Preventive Medicine | null |
38fca7d8-3ec0-4783-b61c-9a812c69e48d | True positive cases are detected by | Specificity | Sensitivity | Positive predictive value | Negative predictive value | 1b | multi | Ans. b (Sensitivity). (Ref. Park, PSM, 17th/pg. 112)TERMDEFINATIONSensitivityThe probability that a person who actually has the disease of interest will have a positive (abnormal) test result. In clinical practice sensitivity is inversely proportional to specificity.SpecificityThe probability that a person who actually... | Social & Preventive Medicine | Screening for Disease |
dd37c0e2-e21a-4fdb-b5c6-19f2b527f379 | In a chalazion with multiple recurrences at the same site the incision and currettage should be: | Followed by cauterisation with carbolic acid | Preceded by cryotherapy | Preceded by intralesional injection of triamcinolone | Replaced by excision biopsy | 3d | single | Ans. Replaced by excision biopsy | Ophthalmology | null |
8ce49abb-29e2-4675-b4f8-e7f6b46121af | In HLA system, the cluster of genes are located in | Chromosome 6 | Chromosome 21 | X-Chromosome | Y-chromosome | 0a | single | (Chromosome 6) (133-A)* Major histocompatibility complexes (MHC) also known as the HLA system (after human leucocyte antigen)This is a cluster of gene on chromosomes 6 that is responsible for immunological specificity* The proteins for which they code are attached to cell surfaces and act as "chaperones" for foreign an... | Orthopaedics | Miscellaneous |
5bf55bb0-a671-426c-a9ac-77cb3ec204f5 | Which of the following ligament help in the transmission of the weight of the upper limb to the axial skeleton? | Coracoclavicular ligament | Coracoacromial ligament | Costoclavicular ligament | Coracohumeral ligament | 0a | single | Coracoclavicular ligament extends from the coracoid process to the undersurface of the clavicle. It is comprised of anterior trapezoid ligament and posterior conoid ligament. It is responsible for suspending the weight of the scapula and the upper limb from the clavicle. It maintains position of the clavicle on the acr... | Anatomy | null |
a08c389f-ece1-48c5-b3db-26da60afe1c6 | Frozen pelvis is usually associated with which of the following conditions? | Tuberculous endosalpingitis | Tuberculous salpingitis | Interstitial tuberculous salpingitis | Subserous myoma | 1b | multi | In tuberculous salpingitis sometimes the tubercles may not be obvious on the peritoneal surface. This type of lesions with intestinal adhesions to such a degree that a surgeon is not able to reach the uterus or adnexa is named frozen pelvis. Any attempt to separate the adhesions may result in intestinal trauma and fist... | Gynaecology & Obstetrics | null |
389faeed-bd76-4b6e-96ab-bb8ddf4c35bd | Incidence of Down's syndrome is directly proportional to | Parity | Consanguinity | Maternal age | Mutations | 2c | single | Ans. c (Maternal age). (Ref. Harrison, Internal Medicine, 16th ed., 383)The incidence of Down ys syndrome is highly correlated to maternal age.QUADRUPLE TEST FOR DOWN'S SYNDROME# AFP |# beta-HCG |# Unconjugated estriol |# Human placental lactogen/placental protein A | | Medicine | Genetics |
6a9e36bc-d145-4eaa-98ae-603e35fe3808 | Equilibrium potential for chlorine: | -70 | 60 | Both | None | 0a | multi | Equilibrium potential is also called isoelectric At this potential there is no movement of ions Equilibrium potential for chlorine in -70 | Anatomy | General anatomy |
80da9246-7853-4883-9799-cd4d3283e75f | All are malignant tumors, except: | Chloroma | Fibromatosis | Askin's tumor | Liposarcoma | 1b | multi | * Fibromatosis are a group of fibroblastic proliferations. *They are locally aggressive, they do not metastasize. | Pathology | General Concepts |
3b2e4014-6f7b-424c-955e-99ad3ea30c1d | Concentration of urea on one side (side A) of permeable membrane is 20 and on other side (side B) is 40. If concentration on side A is increased to 40, what will happen to rate of diffusion? | It will become double | It will become four times | It will be zero | It will be reduced four times | 2c | single | Ans. is 'c' i.e., It will be zero [Ref: Principles of medical physiology p. 71)This question, the concentration gradient is zero as both sides (A & B) have same concentration (40) of urea.Thus there is no diffusion + Rate of diffusion is zero. | Physiology | null |
03ab8785-4b80-4045-b608-cd80361fe7ba | Dose limiting toxicity of amphotericin B is: | Infusion related reaction | Renal tubular acidosis | Myelosuppression | Hypotension | 1b | single | Renal tubular acidosis is the dose limiting toxicity of amphotericin B. Amphotericin B can also cause: Infusion related reactions (not dose related) Hypokalemia Hypomagnesemia | Pharmacology | Anti-Fungal Drugs |
a1b22b80-d35a-4dba-9912-6a4c3b560e36 | when the patient repeate the same answer even when the question is changed is called as | perseveration | puns | clang assosiation | neologism | 0a | multi | * Neologism= they will introduce new words that are not present in one's dictionary , seen in SCHIZOPHRENIA perseveration, === here the same answer will be repeated even when the question is changed, a feature of ORGANIC BRAIN SYNDROME clang, ====subsequent words will have rhyming seen in MANIA puns,=== double meaning ... | Anatomy | General anatomy |
1fe74835-335b-43af-b648-23fcced2ce48 | Thanatology deals with: | Exhumation | Death in all aspects | Unnatu ral sex offences | Body of offence | 1b | multi | Ans: b (death in all aspects) Ref: Reddy, 27th ed,p. 121Thanatology deals with death in all aspects.Types of death1) Somatic death-Complete, irreversible stoppage of circulation breathing and brain function2) Brain death-Characterized by deep unconsciousness with no response to external stimuli, no breathing, no cardia... | Forensic Medicine | Death and Medicolegal Aspects |
23517878-d3ba-4250-b003-3f8333fa4cc6 | Infection of CNS spread in inner ear is through: | Cochlear aqueduct | Endolymphatic sac | Vestibular aqueduct | Hyl fissure | 0a | single | Cochlear aqueduct (Aqueduct of Cochlea) is a connection between scala tympani (containing perilymph) and the subarachnoid space (containing CSF). On occassions, paicularly in young children, the Cochlear aqueduct is large and open.Infection can spread to the inner ear from the infected CSF or vice versa, the cochlear a... | ENT | null |
0fc73274-2422-43ea-8b8e-35eb0c9c1eee | Ideal time to start exhumation - | Mid night | Late evening | Afternoon in proper light | Early morning | 3d | single | Ans. is 'd' i.e., Early morning Exumationo Exumation is lawful digging out of a burried body from the grave for the purpose of identification or determination of cause of death.o Only a magistrate (executive magistrate) can order for exhumation,o In india, there is no time limit for exhumation, i.e. can be done at any ... | Forensic Medicine | Medicolegal Autopsy |
3a8904ba-3dfe-44d4-b5dc-7f58e4a20fd5 | Distance between undersurface of hygienic pontic and gingiva is | 1 mm | 1.5 mm | 2 mm | 2.5 mm | 2c | single | null | Dental | null |
735966f5-5448-4f6d-a45b-b83da6f1f1e6 | A 20 years old boy with known history of mental illness was brought to emergency room with aggressive behaviour and tendency to attack others physically. After psychiatric evaluation, he was prescribed some new drugs and dose of previous drugs changed. After 3 days, he presents to emergency room again with fever (1050C... | Succinyl choline | Dantrolene | Edrophonium | Neostigmine | 1b | multi | (Refer: Kaplan & Sadock's CTP, 10th Ed Chap 34.17 P.7849)
Neuroleptic malignant syndrome
A rare but extremely serious complication of neuroleptic treatment especially with high potency compounds. Evolve over 24-72 hours untreated last for 10 to 14 days , even fatal
Clinical features
Hyperthermia
Muscular rigidity –... | Unknown | null |
53eab8af-3347-412c-95bc-ca74be88d7b6 | Which of the following is responsible for phagocytosis? | C5a | C3a | C3b | TNF-a | 2c | single | The process of phagocytosis is fuher enhanced when microorganisms are coated with specific proteins, opsonins from the serum. Opsonins establish a bond between bacteria and bacteria and the membrane of the phagocytic cell. C3b is opsonin generated by activation of cothe complement pathway. Reference: Harsh Mohan textbo... | Microbiology | Immunology |
b0e1e21c-c37f-4764-b3d0-71d34d1dae3d | All of the following statements about silicosis are true except | Pleural plaques | Prediliction for upper lobes | Calcific hilar lymphadenopathy | Associated with tuberculosis | 0a | multi | With long-term, less intense exposure, small rounded opacities in the upper lobes may appear on the chest radiograph after 15-20 years of exposure, usually without associated impairment of lung function (simple silicosis). Calcification of hilar nodes may occur in as many as 20% of cases and produces a characteristic "... | Anatomy | Respiratory system |
a01ee5ef-08b0-4644-864e-3b84055027f3 | Orally active hormone is ? | TSH | Thyroxine | GH | Prolacin | 1b | multi | Ans. is 'b' i.e., Thyroxine | Pharmacology | null |
508ea8fb-9159-4a66-bc01-4d8f533bf40a | Most common benign tumours during infancy is | Lymphangioma | Hemangioma | Cystic hygroma | Lipoma | 1b | single | An infantile hemangioma is one of the most common benign tumors of infancy and occurs in approximately 5-10% of infants.They occur more frequently in females,premature and low bih weight infants. Reference: GHAI Essential pediatrics, 8th edition | Pediatrics | Childhood tumors |
0409b2af-183f-4b15-b875-7a4c9c7c4b27 | Which one of the statements is false regarding adefovir dipivoxil? | Acyclic nucleotide analogue | Well tolerated orally | Used in chronic hepatitis B infection | Used in anti-retroviral therapy | 2c | multi | Nonselective antiviral drugs: Ribavirin, Lamivudine, Adefovir dipivoxil, Interferon alpha. Adefovir dipivoxil It is the diester prodrug of AMP analogue adefovir which is active against hepatitis B virus (HBV) and some other DNA viruses. Esterases in the intestine and liver release the active drug during absorption to a... | Pharmacology | Chemotherapy |
c8fc6b0e-49dc-4bbe-a0bd-20bfafc5ae73 | Which of the following are lymphomas is associated with HTLV-I virus infection? | Burkitt's lymphoma | B-cell lymphoma | Adult T-cell leukemia and lymphoma | Hodgkin's disease | 2c | single | Ans. is 'c' i.e., Adult T cell leukemia and lymphoma VirusAssociated diseaseHTLV -1 virusAdult T cell lymphoma / leukemia (ATL)Tropical spastic paraparesis (HTLV associated myelopathy or HAM)HTLV - II virus- T cell variant of hairy cell leukemia (not yet conclusively established) | Medicine | Lymphoma |
2380304a-404f-41b1-841b-5b5cd3250699 | Which of the component of respiratory chain reacts directly with molecular oxygen ? | Cyt b | CoQ | Cyt C | Cyt aa3 | 3d | single | Ans. is 'd' i.e., Cyt aa3 | Biochemistry | null |
f1fb4bf9-ee5c-4adb-a66d-a1dd2881be56 | Treatment for brown tumor is | Curettage | Surgical enucleation | Intralesional steroids | Parathyroidectomy | 3d | single | null | Surgery | null |
0d28a58f-5a74-4070-8b14-72baf7d2544e | Cut off limit for deoxygenated hemoglobin for appearance of cyanosis is? | >4 gm% | >5 gm% | < 2 gm% | <4 gm% | 1b | single | Ans. B >5gm%Ref: Ganong, 25th ed. pg. 642Cyanosis appears whenever the magnitude of reduced hemoglobin level of blood in capillaries is >5 gm%. | Physiology | Respiratory System |
043e753c-2c3d-4802-a14b-1392bd4e9b13 | The primary defects in CTEV are the following EXCEPT | Equinus | Adduction | Calcaneus | Varus | 2c | multi | Ans. c (Calcaneus) (Ref. Nelson Paediatrics 17th ed., 2256 and Maheshwari orthopedics 3rd ed., 199)Examination of the infant with CTEV (clubfoot) demonstrates:# Hindfoot equinus,# Hindfoot and midfoot varus,# Forefoot adduction.These findings are secondary to the medial dislocation of the talonavicular joint.CONGENITAL... | Orthopaedics | Congenital Talips Eqino Varvs (C.T.E.V.) |
74cb04af-3259-4353-a254-4e5e2b1cff06 | Best time to do USG in pregnancy, if it is to be done once in entire pregnancy, would be: March 2011 | 6-8 weeks | 10-12 weeks | 18-22 weeks | 34-36 weeks | 2c | single | Ans. C: 18-22 weeks Routine USG at 18-22 weeks gestation has the following effects 1) reduces the incidence of post-term pregnancy (39%) and rates of induction of labour for post-term pregnancy, 2) increases early detection of multiple pregnancy (92%), 3) increases early detection of major fetal anomalies when terminat... | Gynaecology & Obstetrics | null |
7ac4fc4e-2775-4cd5-be90-1ad93ba061bb | Multiple liver secondaries are most common in the following cancers | Head of pancreas | Stomach | Gall bladder | Periampullary | 2c | multi | Carcinoma gallbladder leads to multiple secondaries to liver in advanced stage, and is the most common cause among the given option Ref: Sabiston 20th edition Pgno : 1464-1465 | Anatomy | G.I.T |
ca273d45-49a2-4a05-b897-74e421748e27 | Muscle Relaxant excreted exclusively by Kidney | Gallamine | Atracurium | Atracurium | Sch | 0a | multi | A i.e. Gallamine | Anaesthesia | null |
cbe48013-15ed-459c-9be2-00378730191e | Glucose in renal tubules reabsorbed and is transpoed through the following mechanism: | Na antepo | Na cotranspo | K antepo | K sympo | 1b | single | Glucose reabsorption in the kidneys is similar to glucose reabsorption in the intestine. Glucose and Na+ bind to the sodium-dependent glucose transpoer (SGLT) 2 in the apical membrane, and glucose is carried into the cell as Na+ moves down its electrical and chemical gradient. The Na+ is then pumped out of the cell int... | Physiology | null |
ce0ffcf0-e825-4f9e-ad6c-3a42816a7d42 | Matrix band is difficult to place on -- teeth | MO 25 | DO 37 | DO 24 | MO 24 | 3d | single | null | Dental | null |
1c9dd66b-a26d-4c89-b5fd-2992367327a8 | Which of the following statement is false about erythema marginatum? | Begins as pink papule | Clears from periphery and leave rash behind | Classical rash of acute rheumatic fever | Occurs only in patients with carditis | 1b | multi | ERYTHEMA MARGINATUM: Involves usually trunk or sometimes limb but never on face . Rash stas as pink papule , clears centrally and leave spreading edge behind . It generally occurs only in patients with carditis. | Medicine | Rheumatic Hea disease & infective endocarditis |
69ffe30f-4987-4e1f-b634-4fcddfe5ae92 | Which of the following is an inhibitor of RNA polymerase in eukaryotes ? | Alpha-amanitin | Rifampicin | Both | None | 0a | multi | RNA polymerase II enzyme is inhibited by a-amanitin in eukaryotes. a-amanitin is a potent toxin produced by the poisonous mushroom Amanita phalloides (sometimes called "death cap"). a-Amanitin forms a tight complex with the polymerase, thereby inhibiting mRNA synthesis and, ultimately, protein synthesis. Rifampicin inh... | Anatomy | General anatomy |
3c12f6f6-a308-42ab-b15d-c1ea0b5f122e | 1st evidence of calcification of Lower 2nd premolar is seen in | at birth | 16 wk IU | 1 year after birth | 2 ¼ - 2 ¾ years after birth | 3d | single | null | Dental | null |
ffa5e33f-52e1-4bec-bd44-c097b5df6e5b | A patient presents with malignant hypehermia and metabolic acidosis. Immediate treatment should be staed with: | Intravenous Dantrolene | Sodium bicarbonate | Intravenous fluids | Paracetamol | 0a | single | Ref: Harrison 18th/147 The current treatment of choice for malignant hypehermia is the intravenous administration of dantrolene other impoant measures are: *Discontinuation of triggering agents *Suppeive therapy directed at correcting hypehermia, acidosis, and organ dysfunction. | Pharmacology | Central Nervous system |
b34c4b11-0dd9-4b2e-9bd3-612879edc1aa | In Mallory Weiss syndrome the rupture commonly occurs at - | Gastric cardia | Oesophagus mucosa | Gastro oesophageal junction | Gastroduodenal junction | 0a | multi | In Mallory-Weiss syndrome the majority (75-90%) of tear is located below the gastroesophageal junction, entirely within the gastric cardia.
Only a few of the tears involve the gastro-esophageal junction. | Surgery | null |
2288120d-1713-4ff9-bf11-624cd8ded069 | Glomerulonephritis associated with AIDS is- | Focal segmental GN | PSGN | MPGN | Membranous GN | 0a | single | null | Pathology | null |
2b31c9e6-0bc1-4e36-86c8-3df914ffff27 | Chronotropic effect means:- | Drugs affecting the contractility of hea | Drugs affecting hea rate | Drugs affecting the myocardial blood flow | Drugs affecting diastolic relaxation | 1b | single | Effect Meaning Example Positive chronotropic Increase in hea rate Adrenaline Negative chronotropic Decrease in hea rate Acetylcholine Positive inotropic Increase in contractility Dobutamine Negative inotropic Decrease in contractility Verapamil Positive dromotropic Increase in AV conduction Dobutamine Negative dromotro... | Pharmacology | CHF, Angina Pectoris and Myocardial Infarction |
da7e2e71-7904-4baa-ab0c-03e203dc5cc7 | The drug used in absence seizures and having a narrow spectrum of antiepileptic activity is : | Lamotrigine | Ethosuximide | Sodium valproate | Primidone | 1b | single | null | Pharmacology | null |
10551eaa-4cb5-4e66-84f4-683ecb7a8a95 | Empyema necessitans is defined as so when ? | Plural empyema is under pressure | Pleural empyema has ruptured into bronchus | Pleural empyema has ruptured into the pericardium | Pleural empyema is showing extension to the subcutaneous tissue | 3d | single | Ans. is 'd' i.e., Pleural empyema is showing extension to the subcutaneous tissue | Surgery | null |
6aa8151c-e20c-4493-853e-d43368d7654f | Which among the following is a sure sign of hea failure in an infant with congenital hea disease? | Basal crepitations | JVP | Pedal oedema | Liver enlargement | 3d | single | The most common symptom of hea failure is tachypnea with grunting, gasping breathing, or breathlessness with feeding. A respiratory rate consistently above 60 is seen. Poor weight gain from diminished intake and increased work of breathing is the rule. Cool, moist skin; a diminished and rapid aerial pulse; and hepatic ... | Pediatrics | null |
3558463c-30b7-4ed0-a34e-099879ea03cb | Which nerve is compressed in carpal tunnel syndrome? | Radial nerve | Anterior Interosseus nerve | Superficial palmar branch of radial nerve | Median Nerve | 3d | single | Ans. is 'd' i.e., Median Nerve Entrapment neuropathiesi) Carpal tunnel:- Median nerve (carpal tunnel syndrome)ii) Cubital tunnel:- Ulnar nerve (cubital tunnel syndrome)iii) Guyon's canal:- Ulnar nerve (Guyan's canal syndrome)iv) Tarsal tunnel:- Posterior tibial nerve (Tarsal tunnel syndrome)v) Inguinal ligament:- Later... | Orthopaedics | Peripheral Nerve Injuries |
fec02924-af8c-4c3f-95f7-5cbd1804d46f | Ectopia cordis is associated with the following organ ? | Lens | Lungs | Hea | Liver | 2c | single | Failure of fusion of the two sternal bars during embryonic development produces congenital sternal cleft, which may involve the upper, lower, or entire sternum. In its severe form, this defect is usually associated with ectopia cordis and congenital hea lesions. Ectopia cordis is location of the hea outside of the thor... | Anatomy | null |
99cac344-a8af-49fb-b3b5-1ce44b66712c | Fenestrated capillaries are found in all except :September 2009 | Renal glomeruli | Intestinal villi | Pancreas | Muscle | 3d | multi | Ans. D: MuscleContinuos capillariesLocation: muscle, lung, central nervous system and skin.Composition: endothelial cells contain numerous pinocytotic vesicles, pericytes are enclosed by a basement membrane.Fenestrated CapillariesLocation: endocrine glands, sites of fluid and metabolite absorption: renal corpuscles, in... | Anatomy | null |
7aa37a05-1c61-473f-aae5-3ea00b058822 | White polished rice causes deficiency of - | Thiamine | Tryptophan | Riboflavin | Protein | 0a | single | Ans. is 'a > c > d' i.e., Thiamine > Riboflavin > Protein o Rice is the most common staple food. Rice proteins are richer in lysine than other cereal proteins, and for this reason, rice protein is considered to be a better quality. Rice contains 6.8 gm of protein per 100 gm.o Milling process deprives rice grain of its ... | Social & Preventive Medicine | Vitamins |
c4a0b6d0-0a39-4dc2-8c44-fbe416638712 | Sialogram of a normal salivary gland appears as: | Leafy tree | Leafless tree | Sialolithiasis | Sialgectasia | 1b | single | null | Radiology | null |
fe07aa6f-ce14-4370-a1a2-e881cc95f1f2 | In chronic Hepatitis B infection, which one of the following markers is indicative of active viral replication and the corresponding risk of disease transmission ? | HBe antigen | HBs antigen | Anti - HBe | Anti - HBs | 0a | single | Ans. is 'a' i.e., HBe antigen | Microbiology | null |
6153d6b8-b70a-4139-b731-f660eeacdb29 | Multiple cystic lesions seen in muscle and brain of 16 year old boy died of Status epilepticus. The diagnosis is | Cerebral amebiasis | Neurosarcoidosis | CNS toxoplasmosis | Neurocysticercosis | 3d | single | (D) Neurocysticercosis# Neurocysticercosis (NCC) is caused by CNS infection with the pork tapeworm Taenia solium.> Demographics & clinical presentation: The disease is endemic in Central and South America, Asia and Africa. There is a variable time interval between point of infection and the onset of symptoms (ranging f... | Radiology | Nervous System |
79a665eb-8379-48e8-8314-ed8666e866a0 | At which of the following levels the predominant regulation of gene expression of both prokaryotes and eukaryotes take place? | DNA replication | Transcription | Translation | Post-translational | 1b | multi | Expression of a functional gene product from genes is the gene expression. The functional product is not always proteins. Non-protein coding genes are also expressed as functional RNAs (tRNA, snRNA, miRNA etc.) Regulation of gene expression occurs at transcriptional level in both prokaryotes and eukaryotes. | Biochemistry | Transcription |
dfda7452-0caa-4533-b2c4-58887473a22d | A 17-year-old boy presented with TLC of 138 x 109 /L with 80% blasts on the peripheral smear. Chest X-ray demosnstrated a large mediastinal mass. Immunophenotyping of this patient's blasts would most likely demonstrate: | No surface antigens (null phenotype) | An immature T cell phenotype (Tdt/D34/CD7 positive) | Myeloid markers, such as CD13, CD33 and CD15 | B cell markers, such as CD 19, CD20 and CD22 | 1b | single | Ans. is 'b' i.e. an immature T cell phenotype. Clues given in the question are -Increased leucocyte count with blasts constituting 80% of the cellsPresence of mediastinal mass on chest X-ray.Adolescent maleThese findings are suggestive of acute lymphoblastic leukemia of the T cell lineage.Increased leucocyte count in t... | Pathology | Blood |
a7e733f7-3204-485a-bca9-699daf7641b4 | All are features of Trachoma stage III, except – | Herbert's pits | Pannus | Necrosis in scar | Scar on tarsal conjunctiva | 1b | multi | Stage III of trachoma is cicatrising or scarring stage. So, Herbert pits (are healed scars of Herbert follicles), scar on tarsal conjunctiva & necrosis in scar are all the features of stage III. Where as herbert follicles (IIa), papillary hyperplasia (IIb), Pannus is found in stage II. | Ophthalmology | null |
5988228a-d472-4b56-bd9b-2d08503818a2 | The following structure is involved in Dupuytren's contracture - | Thickening of the palmar fascia | Thickening of the dorsal fascia | Contracture of the flexor tendons | Post burns contracture | 0a | single | Dupuytren&;s contracture is characterised by a flexion deformity of one or more fingers due to thickening and shoening of palmar aponeurosis.Normally palmar aponeurosis is thin but tough membrane lying Immediately beneath the skin of the palm. Proximally it is in continuation with palmaris longus tendon. Distally it di... | Orthopaedics | Bony dysplasia and soft tissue affection |
2d744bcb-7ac4-44a3-a1a9-f7839da19e63 | Drug of choice for psychosis in Parkinson's disease is: | Clozapine | Haloperidol | Lithium | Risperidone | 0a | single | If a patient with Parkinson's disease develops psychotic symptoms, the treatment becomes complicated as most of the anti psychotics cause drug induced Parkinsonism. Since clozapine has minimal extrapyramidal side effects such as parkinsonian side effects, it is preferred. | Psychiatry | Miscellaneous |
04b93e1a-ca9b-4ce9-a718-3f382fb6bd55 | Painless discharge from ear and multiple tympanic membrane perforations are characteristic of ? | Tuberculous otitis media | Fungal otitis media | Serous otitis media | Viral otitis media | 0a | single | Ans. is 'a' i.e., Tubercular otitis media | ENT | null |
a3b6bf39-acbe-46c7-a5a5-f5a7ac1bd618 | Jaipur foot was invented by ? | P. K. Sethi | S. K. Verma | B. L. Sehgal | H. R. Gupta | 0a | single | Ans. is 'a' i.e., P. K. Sethi P. K. Sethi. Pramod Karan Sethi (28 November 1927 - 6 January 2008) was an Indian ohopaedic surgeon. With Ram Chandra Sharma, he co-invented the "Jaipur foot", an inexpensive and flexible aificial limb, in 1969. | Surgery | null |
78af7423-9f79-49a1-b600-6de1a9e4cfad | Reacts with soadaline | Methoxyfluene | Ketamine | Trilene | All | 2c | multi | C i.e. Trilene | Anaesthesia | null |
c7c3adcb-29a0-4114-b1a2-5de7549ffa8e | Ca prostate commonly metastasises to the veebrae: | Because valveless communication exist with Batson's periprostatic plexus. | Via drainage to Sacral lymph node | Of direct Spread | None of the above | 0a | multi | Prostate cancer homing to the lumbar spine mediated by the connection of the Batson's periprostatic venous vessel to the veebral venous plexus. Ref: The Biology of Skeletal Metastases: Volume 118, 2004, Page 292; bailey and Love's Sho Practice of Surgery, 23rd Edition, Page 1250; Clinical Surgery By S. Das, Page 196. | Surgery | null |
ca6a367a-772e-4fd0-aa31-7f14a2efa2b0 | All of following inhibit peripheral conversion of T4 and T3 except - | Propylthiouracil | Methimazole | Proparanolal | Amiodarone | 1b | multi | Ans is 'b' i.e. Methimazole o Propylthiouracil, propranolal, amiodarone and glucocoicoids inhibit peripheral conversion of T4 and T3. | Pharmacology | null |
a50ad786-a7f6-40fe-98f2-e684bd56839b | The following drug is indicated in the treatment of pityriasis versicolar: | Ketoconazole. | Metronidazole. | Griseofulvin. | Chloroquine. | 0a | single | Ans. is 'a' i.e. Ketoconazole T/T of Pityriasis versicolor -New t/t (Antifungal)Old t/tTopical|MiconazoleClotrimazoleEconazoleShampoo| 1. KetoconazoleOral| 1. ItraconazoleWhitfield's ointment (3% salicylic acid and 6% Benzoic acid)Selenium disulfide shampooSodium thiosulphate solution | Unknown | null |
38bd8016-eca6-49c1-94ff-0390746e510a | All are relevant in compament syndrome except: | Fasciotomy | Splitting of tight pop cast | Reexploration | Exercise | 3d | multi | D i.e. Excercise Excercise may increase intra compamental pressure & muscle edema, so it is avoided in cases of acute compamental syndromeQ. | Surgery | null |
83061723-d262-4816-98bb-5a8d364171ad | Cigar bodies are seen in? | Sporotrichosis | Chromoblastomycosis | Mycetoma | Basidiomycosis | 0a | single | In sporotrichosis, direct microscopic examination of KOH mounts of necrotic materials or histopathological examination of tissue section stained by methamine silver stain may yield a diagnosis. The characteristics feature is the asteroid body or cigar body: a rounded or oval, basophilic,yeast-like, cigar-shaped body 3-... | Pathology | dermatology and infectious disease |
4ddfbcd8-4f7c-48ff-bf1f-fab1104407b9 | Cancers associated with excess fat intake are/is ? | Breast | Colon | Prostate | All | 3d | multi | Answer is 'a' i.e. Breast; 'b' i.e. Colon; 'c' i.e. prostate | Surgery | null |
64e7f588-39c0-43bc-bed1-7638132866be | Morphine causes vomiting by acting on- | C.T.Z | Gastric mucosa | Both of the above | None of the above | 0a | multi | Ans. is 'a' i.e., C.T.Z | Pharmacology | null |
99cb38d9-0c57-4d30-b9b6-863200a406b2 | Blood smear is best seen at pH of - | 7.2 | 6.8 | 6.6 | 7 | 1b | single | null | Pathology | null |
387b5eba-6d6b-4c56-8e99-f398a4fffe39 | Thumb sign in lateral X-ray of neck seen in: | Epiglottitis | Internal hemorrhage | Saccular cyst | Ca epiglottis | 0a | single | In epiglottis: A plain lateral soft tissue radiograph of neck shows the following specific features Thickening of the epiglottis--the thumb sign Absence of a deep well-defined vallecula--the vallecula sign Steeple sign i.e. Narrowing of subglottic region is seen in chest X-ray of patients of laryngotracheobronchitis (i... | ENT | null |
9dd53b92-d319-4333-8327-b1d0ba0becf2 | A 56 year old female presented with breast carcinoma and she was prescribed herceptin (trastuzumab). Which of the following statements regarding this drug is true? | It is an antibody produced entirely from mouse contraining no human component | It is a monoclonal antibody produced by injecting her-2 antigen | It is a polyclonal antibody | It is a monoclonal antibody containing only human component | 1b | multi | US Brand Name Herceptin Descriptions Trastuzumab is used to treat new cases of breast cancer or disease that has spread to other pas of the body. It may prevent the growth of some breast tumors that produce extra amounts of a ceain substance known as the HER2 protein. Trastuzumab should only be used in patients whose b... | Pharmacology | Chemotherapy |
83898956-9662-4bde-bee2-e29ded485c04 | Light reflex absent but accommodation reflex present is seen in: | Hutchison's pupil | Argyl Robeson pupil | Adie pupil | Homer's syndrome | 1b | single | B i.e. Argyl Robeson pupil | Ophthalmology | null |
86da84d8-7c13-4c5a-bfd6-2887ff5095ef | Genital tubercle forms which of the following pa in females? | Labia majora | Labia minora | Clitoris | None | 2c | multi | * The genital tubercle is situated in the midline between the urogenital membrane and the lower pa of the anterior abdominal wall. The genital tubercle becomes cylindrical and forms the clitoris. It has to be noted that in fetuses about 3-4 months old, the genital tubercle is equally developed in both the male and fema... | Anatomy | General anatomy |
5690f4a6-8d44-4b94-8644-b4433041cbb8 | During antenatal visit 24 year old primi is discovered to be positive for Hepatitis - B . How will you manage her newborn | Give Hepatitis - B immunoglobulin immediately after delivery | Test for neonatal hepatitis - B antigen status | Give Hepatitis B immunoglobulin and immunize against Hepatitis B (vaccine) | None of the above | 2c | multi | If mother is seropositive for hepatitis B surface antigen, then neonate should be passively immunized with immunoglobulins along with routine immunization with hepatitis B-vaccine. | Gynaecology & Obstetrics | null |
d677d7f5-5d45-4864-a5df-224b0fb492e8 | Cryosurgery is effective in all except | Chronic cervicitis | Squamous intraepithelial lesion | Condyloma accuminata | Cases with severe dysplasia or CIS lesion | 3d | multi | Indications of cryosurgery Cervical ectopy Benign cervical lesions CIN Condyloma accuminata Leukoplakia VIN < 2cms size VAIN Vault granulation tissue Palliative measure to arrest bleeding in CA cervix or large fungating recurrent vulval carcinoma Ref: D.C.DUTTAS TEXTBOOK OF GYNECOLOGY; 6th edition; Pg no:591 | Gynaecology & Obstetrics | Gynaecological diagnosis and operative surgery |
c908d9d6-caa2-413b-8e96-9a7bc347074c | What is the mechanism of action of glucagon? | Inositol Pathway | Arachidonic Acid Pathway | c-GMP Pathway | c-AMP Pathway | 3d | single | ANSWER: (D) c AMP pathwayREF: Guyton 12th ed pg 948Glucagon causes glycogenolysis in the liver and this in turn increases the blood glucose levels by the following mechanismGlucagon activates adenylyl cyclase in the hepatic cell membraneThis causes formation of cAMPActivation of protein kinase regulator proteinActivati... | Physiology | Pancreas |
8f6ab717-d3fc-4f2e-91da-ae8e4619aa33 | Ochsner- Sherren regime is used in management of: | Appendicular abscess | Chronic appendicitis | Appendicular mass | Acute appendicitis | 2c | single | MANAGEMENT OF APPENDICULAR MASS If an appendix mass is present and the condition of the patient is satisfactory, the standard treatment is the conservative Ochsner-Sherren regimen. Surgery done during appendicular lump formation can lead to increased risk of injury of cecum. To know whether the lump is appendicular lum... | Surgery | Vermiform Appendix |
d8e3ccae-945b-422b-9f95-c6ead1aba6a7 | First stage of labour is up to : | Rupture of membranes | 3/5 dilatation of cervix | Full dilatation of cervix | Crowing of head | 2c | single | Full dilatation of cervix | Gynaecology & Obstetrics | null |
58268dd7-30dd-4526-aee4-49542396e839 | Celiac plexus block all the following is true except- | Relieved pain from gastric malignancy | cause hypotention | Can be used to provide anesthesia for intra abdominal surgery | Can be given only by retrocrural {classic}. approach | 3d | multi | Ohostatic hypotension occur more often with the retrocrural approach Can be used to provide anesthesia for intra abdominal surgery relive pain from gastric malignancy | Anaesthesia | Regional anaesthesia |
7a67eef0-0c2c-4f5c-9ecc-2a1d1751ad2f | Most common mutation in haemophilia is: | Intron 1 inversion | Intron 22 | 619 bp deletion | 3.7 bp deletion | 1b | single | Genetic abnormalities in haemophilia : Inversions: Intron 22 inversion, Intron 1 inversion Point mutations: Missense mutation, nonsense mutation, frameshift mutation Deletion of pa or whole of gene Inseion of repetitive sequences Splicing errors affecting production of mRNA Hemophilia A(factor 8 deficiency) -x linked r... | Pathology | Blood disorder |
53644edf-7550-4756-abd8-364aedca5d11 | Trotter's triad includes all except - | Sensory disturbance over distribution of 5th cranial nerve | Diplopia | Conductive deafness | Palatal palsy | 1b | multi | Nasopharyngeal can cause conductive deafness (eustachian tube blockage) ipsilateral temporoparietal neuralgia (involvement of CN V) and palatal paralysis (CN X) collectively called Trotters triad.
Ref. Dhingra 6/e, p 251 | ENT | null |
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