SchemaBio_Bundle

@@ -1,54 +1,55 @@
----
-language:
-  - en
-license: other
-tags:
-  - biology
-  - genomics
-  - medical
-  - bioinformatics
-  - variant-annotation
-  - clinical
-  - wgs
-  - wes
-pretty_name: SchemaBio Bundle
----
-# 🧬 SchemaBio Bundle
-## 📖 Overview
-This dataset is a comprehensive, meticulously curated, one-stop annotation library designed for bioinformatics and genomic variant analysis (e.g., WES/WGS pipelines). It aggregates essential variant effect predictors, clinical databases, and genomic reference files into a unified repository, significantly reducing the time spent on data collection, format alignment, and preprocessing.
-## 🗂️ Included Data & Sources
-This repository includes data from the following categories:
-1. **Variant Effect Predictors & Scores:** AlphaMissense, EVOScore2, Pangolin.
-2. **Clinical & Population Frequencies:** gnomAD, CIViC, mskcc_hotspot.
-3. **Genomic References & Regions:** UCSC annotations (`cytoband`, `ncbiRefSeq.gtf`), Ensembl references (`GRCh38/37 FASTA`, `vep_cache`), ManeSelectBed.
-## ⚖️ Licensing & Commercial Use
-**Great news: All underlying datasets included in this repository currently permit commercial use**, provided that users strictly adhere to their respective attribution and share-alike requirements.
-Because this repository acts as an aggregator, **it does not fall under a single license**. You must comply with the individual licenses of the respective underlying data sources. The table below outlines the specific license for each component:
-### 📊 Database Licenses Summary
-| Database / Source | Version | Official License | Commercial Use | Redistribution | Key Requirements & Notes |
-| :--- | :--- | :--- | :--- | :--- | :--- |
-| [**AlphaMissense**](https://zenodo.org/records/10813168) | v3 | **CC BY 4.0** | ✅ Allowed | ✅ Allowed | Must attribute to DeepMind Technologies Limited. |
-| [**EVOScore2**](https://huggingface.co/datasets/pzweuj/EVOScore-2) | 20260128 | **MIT** | ✅ Allowed | ✅ Allowed | Must include the original copyright notice. |
-| [**Pangolin**](https://zenodo.org/records/15649338) | v1 | **CC BY 4.0** | ✅ Allowed | ✅ Allowed | Must provide proper attribution. |
-| [**ManeSelectBed**](https://github.com/pzweuj/ManeSelectBed) | v49 | **MIT** | ✅ Allowed | ✅ Allowed | Must include the original copyright notice. |
-| [**mskcc_hotspot**](https://www.cancerhotspots.org/) | v2 | **ODbL** | ✅ Allowed | ✅ Allowed | **Share-Alike:** If you modify/adapt this database, the derivative must also be ODbL. |
-| [**CIViC**](https://civicdb.org/welcome) | 20260301 | **CC0 1.0** | ✅ Allowed | ✅ Allowed | Public Domain. No restrictions. |
-| [**gnomAD**](https://gnomad.broadinstitute.org/) | v4.1 | **Unrestricted** | ✅ Allowed | ✅ Allowed | Broad Institute claims no restrictions on use. |
-| [**UCSC Data**](https://hgdownload.soe.ucsc.edu/goldenPath) | / | **Public Domain** | ✅ Allowed | ✅ Allowed | Publicly funded data, free for all uses. |
-| [**Ensembl Data**](https://ftp.ensembl.org/pub/release-115/) | release 115 | **Unrestricted** | ✅ Allowed | ✅ Allowed | EMBL-EBI places no restrictions on use or redistribution. |
-*Disclaimer: The creator of this combined dataset claims no ownership over the original source data. Users are solely responsible for ensuring their downstream use complies with the original data providers' terms.*

+---
+language:
+  - zh
+license: other
+tags:
+  - biology
+  - genomics
+  - medical
+  - bioinformatics
+  - variant-annotation
+  - clinical
+  - wgs
+  - wes
+pretty_name: SchemaBio Bundle
+---
+# 🧬 SchemaBio Bundle
+[English](./README_EN.md) | 中文
+## 📖 概述
+本数据集是一个全面、精心整理的一站式注释库，专为生物信息学和基因组变异分析设计（如 WES/WGS 流水线）。它将核心的变异效应预测器、临床数据库和基因组参考文件整合到统一的资源库中，大幅减少数据收集、格式对齐和预处理的时间。
+## 🗂️ 包含数据与来源
+本资源库包含以下类别的数据：
+1. **变异效应预测器与评分：** AlphaMissense、EVOScore2、Pangolin。
+2. **临床与人群频率数据：** gnomAD、CIViC、mskcc_hotspot。
+3. **基因组参考与区域：** UCSC 注释文件（`cytoband`、`ncbiRefSeq.gtf`）、Ensembl 参考文件（`GRCh38/37 FASTA`、`vep_cache`）、ManeSelectBed。
+## ⚖️ 许可证与商业使用
+**好消息：本资源库包含的所有基础数据集目前均允许商业使用**，前提是用户严格遵守各自的署名和相同方式共享要求。
+由于本资源库作为聚合器，**它不受单一许可证约束**。您必须遵守各基础数据源的单独许可证。下表概述了每个组件的具体许可证：
+### 📊 数据库许可证汇总
+| 数据库 / 来源 | 版本 | 官方许可证 | 商业使用 | 再分发 | 关键要求与说明 |
+| :--- | :--- | :--- | :--- | :--- | :--- |
+| [**AlphaMissense**](https://zenodo.org/records/10813168) | v3 | **CC BY 4.0** | ✅ 允许 | ✅ 允许 | 必须署名 DeepMind Technologies Limited。 |
+| [**EVOScore2**](https://huggingface.co/datasets/pzweuj/EVOScore-2) | 20260128 | **MIT** | ✅ 允许 | ✅ 允许 | 必须包含原始版权声明。 |
+| [**Pangolin**](https://zenodo.org/records/15649338) | v1 | **CC BY 4.0** | ✅ 允许 | ✅ 允许 | 必须提供适当署名。 |
+| [**ManeSelectBed**](https://github.com/pzweuj/ManeSelectBed) | v49 | **MIT** | ✅ 允许 | ✅ 允许 | 必须包含原始版权声明。 |
+| [**mskcc_hotspot**](https://www.cancerhotspots.org/) | v2 | **ODbL** | ✅ 允许 | ✅ 允许 | **相同方式共享：** 如果您修改/改编此数据库，衍生作品也必须采用 ODbL 许可证。 |
+| [**CIViC**](https://civicdb.org/welcome) | 20260301 | **CC0 1.0** | ✅ 允许 | ✅ 允许 | 公共领域。无限制。 |
+| [**gnomAD**](https://gnomad.broadinstitute.org/) | v4.1 | **无限制** | ✅ 允许 | ✅ 允许 | Broad Institute 声明对使用无限制。 |
+| [**UCSC Data**](https://hgdownload.soe.ucsc.edu/goldenPath) | / | **公共领域** | ✅ 允许 | ✅ 允许 | 公共资助数据，可自由用于任何用途。 |
+| [**Ensembl Data**](https://ftp.ensembl.org/pub/release-115/) | release 115 | **无限制** | ✅ 允许 | ✅ 允许 | EMBL-EBI 对使用或再分发无限制。 |
+*免责声明：本组合数据集的创建者对原始源数据不主张任何所有权。用户需自行确保其下游使用符合原始数据提供者的条款。*

README_EN.md ADDED Viewed

	@@ -0,0 +1,55 @@

+---
+language:
+  - en
+license: other
+tags:
+  - biology
+  - genomics
+  - medical
+  - bioinformatics
+  - variant-annotation
+  - clinical
+  - wgs
+  - wes
+pretty_name: SchemaBio Bundle
+---
+# 🧬 SchemaBio Bundle
+English | [中文](./README.md)
+## 📖 Overview
+This dataset is a comprehensive, meticulously curated, one-stop annotation library designed for bioinformatics and genomic variant analysis (e.g., WES/WGS pipelines). It aggregates essential variant effect predictors, clinical databases, and genomic reference files into a unified repository, significantly reducing the time spent on data collection, format alignment, and preprocessing.
+## 🗂️ Included Data & Sources
+This repository includes data from the following categories:
+1. **Variant Effect Predictors & Scores:** AlphaMissense, EVOScore2, Pangolin.
+2. **Clinical & Population Frequencies:** gnomAD, CIViC, mskcc_hotspot.
+3. **Genomic References & Regions:** UCSC annotations (`cytoband`, `ncbiRefSeq.gtf`), Ensembl references (`GRCh38/37 FASTA`, `vep_cache`), ManeSelectBed.
+## ⚖️ Licensing & Commercial Use
+**Great news: All underlying datasets included in this repository currently permit commercial use**, provided that users strictly adhere to their respective attribution and share-alike requirements.
+Because this repository acts as an aggregator, **it does not fall under a single license**. You must comply with the individual licenses of the respective underlying data sources. The table below outlines the specific license for each component:
+### 📊 Database Licenses Summary
+| Database / Source | Version | Official License | Commercial Use | Redistribution | Key Requirements & Notes |
+| :--- | :--- | :--- | :--- | :--- | :--- |
+| [**AlphaMissense**](https://zenodo.org/records/10813168) | v3 | **CC BY 4.0** | ✅ Allowed | ✅ Allowed | Must attribute to DeepMind Technologies Limited. |
+| [**EVOScore2**](https://huggingface.co/datasets/pzweuj/EVOScore-2) | 20260128 | **MIT** | ✅ Allowed | ✅ Allowed | Must include the original copyright notice. |
+| [**Pangolin**](https://zenodo.org/records/15649338) | v1 | **CC BY 4.0** | ✅ Allowed | ✅ Allowed | Must provide proper attribution. |
+| [**ManeSelectBed**](https://github.com/pzweuj/ManeSelectBed) | v49 | **MIT** | ✅ Allowed | ✅ Allowed | Must include the original copyright notice. |
+| [**mskcc_hotspot**](https://www.cancerhotspots.org/) | v2 | **ODbL** | ✅ Allowed | ✅ Allowed | **Share-Alike:** If you modify/adapt this database, the derivative must also be ODbL. |
+| [**CIViC**](https://civicdb.org/welcome) | 20260301 | **CC0 1.0** | ✅ Allowed | ✅ Allowed | Public Domain. No restrictions. |
+| [**gnomAD**](https://gnomad.broadinstitute.org/) | v4.1 | **Unrestricted** | ✅ Allowed | ✅ Allowed | Broad Institute claims no restrictions on use. |
+| [**UCSC Data**](https://hgdownload.soe.ucsc.edu/goldenPath) | / | **Public Domain** | ✅ Allowed | ✅ Allowed | Publicly funded data, free for all uses. |
+| [**Ensembl Data**](https://ftp.ensembl.org/pub/release-115/) | release 115 | **Unrestricted** | ✅ Allowed | ✅ Allowed | EMBL-EBI places no restrictions on use or redistribution. |
+*Disclaimer: The creator of this combined dataset claims no ownership over the original source data. Users are solely responsible for ensuring their downstream use complies with the original data providers' terms.*