Answer: tested

Compound: LENIOLISIB
SMILES: CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1
Target: P17252, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(2-((4-(1-(3-(1H-imidazole-1-yl)benzyl)piperidin-4-yl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide
SMILES: COc1cc(NC(=O)c2cc(=O)c3ccccc3o2)c(C(=O)Nc2ccc(C3CCN(Cc4cccc(-n5ccnc5)c4)CC3)cc2)cc1OC
Target: Q92887, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4256458
SMILES: OCc1nc2ccccc2n1CC(O)Cn1ccc2ccccc21
Target: Q9NSA0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 5-chloro-3-(N-(3,4-diethoxyphenyl)-N-methylsulfamoyl)-N-(3-(methylsulfonyl)phenyl)thiophene-2-carboxamide
SMILES: CCOc1ccc(N(C)S(=O)(=O)c2cc(Cl)sc2C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1OCC
Target: Q13133, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: BROMOSPORINE
SMILES: CCOC(=O)Nc1cc(-c2ccc(C)c(NS(C)(=O)=O)c2)nn2c(C)nnc12
Target: Q6PL18, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(5-((4-bromo-2-hydroxy-5-((3-methyl-2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)methyl)pyridin-3-yl)nicotinamide
SMILES: CN1C(=O)S/C(=C\c2cc(OCc3cncc(NC(=O)c4cccnc4)c3)c(O)cc2Br)C1=O
Target: Q8N884, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 2-(3-amino-1-phenyl-1H-1,2,4-triazol-5-ylthio)-N-methyl-N-phenylacetamide
SMILES: CN(C(=O)CSc1nc(N)nn1-c1ccccc1)c1ccccc1
Target: Q14432, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 5H-dibenzo[b,e][1,4]diazepin-11(10H)-one
SMILES: O=C1Nc2ccccc2Nc2ccccc21
Target: Q07820, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SGC-CLK-1N
SMILES: COc1cc(Nc2nc(C)cc(-c3cnn4nc(OC)ccc34)n2)cc(C(F)(F)F)c1
Target: HIPK1 (Q86Z02), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: FOSTAMATINIB
SMILES: COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)N(COP(=O)(O)O)C(=O)C(C)(C)O4)n2)cc(OC)c1OC
Target: Q16644, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 8-chloro-7,9-dimethyl-N-((2-methylpyrimidin-5-yl)methyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine hydrochloride
SMILES: Cc1ncc(CNc2ncnc3c2sc2nc(C)c(Cl)c(C)c23)cn1.Cl
Target: P08173, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 1H-indol-5-ol
SMILES: Oc1ccc2[nH]ccc2c1
Target: O00459, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: COPANLISIB
SMILES: COc1c(OCCCN2CCOCC2)ccc2c1N=C(NC(=O)c1cnc(N)nc1)N1CCN=C21
Target: P22736, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: US9688615, 38
SMILES: NCc1nc2cc(C(F)(F)F)c(C(F)(F)F)cc2[nH]1
Target: Q00975, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4259551
SMILES: C=CCNc1nc(N2CCCC2)nc2ccccc12
Target: Q9BRX2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: DALFAMPRIDINE
SMILES: Nc1ccncc1
Target: Q9BVK2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID852593
SMILES: C=CCn1c(N)cc(=O)nc1SCC(=O)Nc1ccccc1
Target: P07382, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(1-(4-chlorobenzyl)piperidin-4-yl)-5-(1H-pyrrol-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-amine
SMILES: Clc1ccc(CN2CCC(Nc3c(-c4cc[nH]c4)cnc4[nH]ccc34)CC2)cc1
Target: JAK3 (P52333), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4265138
SMILES: O=C(O)C1CCCCC1C(=O)NCCc1cccc(Cl)c1
Target: Q16543, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: DEXIBUPROFEN
SMILES: CC(C)Cc1ccc([C@H](C)C(=O)O)cc1
Target: O60341, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 6-Methyl-3-(3-phenyl-1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
SMILES: CC1=Nn2c(nnc2-c2cc(-c3ccccc3)[nH]n2)SC1
Target: O43865, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851942
SMILES: CCc1ccc2nc(SCC(=O)N(CC)CC)c(C#N)cc2c1
Target: Q14432, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4240504
SMILES: Cc1ccc(C(C(=O)NC2CCCCC2)N2CCCC2)cc1
Target: Q9NS69, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-(4-hydroxy-3-methoxybenzylidene)-6-((10-hydroxydecyl)oxy)benzofuran-3(2H)-one
SMILES: COc1cc(/C=C2\Oc3cc(OCCCCCCCCCCO)ccc3C2=O)ccc1O
Target: P16233, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SID24789741
SMILES: Oc1c(CN2CCOCC2)ccc2ccccc12
Target: P09488, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone
SMILES: Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)NCCONC(=N)N
Target: P00747, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)piperidin-1-yl)nicotinate
SMILES: CCOC(=O)c1cncc(N2CCC([C@H](N)Cc3cc(F)ccc3F)CC2)c1
Target: Q86TI2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7974904
SMILES: CC(C(=O)NCc1ccccn1)N1C(=O)c2ccccc2C1=O
Target: Q9NYK1, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID861956
SMILES: CC(C)OC(=O)CSc1nnc(-c2cccnc2)n1N
Target: Q9BY41, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7968125
SMILES: Cc1cccc(C2CC(c3ccc(Cl)cc3)Nc3nc(N)nn32)c1
Target: O14880, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SOTRASTAURIN
SMILES: CN1CCN(c2nc(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc3n2)CC1
Target: EPHA1 (P21709), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: BMS-911543
SMILES: CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3cc(C)n(C)n3)nc21
Target: O75496, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: PF-03814735
SMILES: CC(=O)NCC(=O)N1[C@@H]2CC[C@H]1c1ccc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)cc12
Target: PRKCQ (Q04759), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: KW-2449
SMILES: O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1
Target: P43490, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: PH-797804
SMILES: CNC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1
Target: MYLK (Q15746), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4246687
SMILES: CCOc1ccccc1NS(=O)(=O)c1c(C)noc1C
Target: P48147, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: KW-2449
SMILES: O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1
Target: Q9NYW5, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-((5-cyano-4-(3,4-dimethoxyphenyl)-6-hydroxypyrimidin-2-yl)thio)-N-(4-sulfamoylphenyl)acetamide
SMILES: COc1ccc(-c2nc(SCC(=O)Nc3ccc(S(N)(=O)=O)cc3)nc(O)c2C#N)cc1OC
Target: P00915, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (E)-3-(3-((E)-3,5-dihydroxystyryl)-4-hydroxyphenyl)-N-methylacrylamide
SMILES: CNC(=O)/C=C/c1ccc(O)c(/C=C/c2cc(O)cc(O)c2)c1
Target: Q96FA3, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID850986
SMILES: CC1Oc2ccccc2N(Cc2ccccc2Cl)C1=O
Target: Q9UBN7, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-((S)-3-(naphthalen-2-yl)-1-oxo-1-(piperidin-1-yl)propan-2-yl)-3-phenylpropanamide
SMILES: COc1cc(C)c(S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N2CCCCC2)c(C)c1C
Target: P47901, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7976733
SMILES: CC(C)=CCC/C(C)=C/CC/C(C)=N/O
Target: O09178, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid
SMILES: CCC(C(=O)Nc1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1
Target: Q03181, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (4-methylpiperazin-1-yl)(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-methanone
SMILES: CN1CCN(C(=O)c2ccc(-c3noc(C(F)(F)F)n3)cc2)CC1
Target: Q92769, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: TRYPTOPHAN
SMILES: N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
Target: P16615, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: TRYPTOPHAN
SMILES: N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
Target: Q7Z5P4, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4245126
SMILES: COc1ccc(NC(=O)C2C(=O)NC3(C)CC2c2ccccc2O3)cc1
Target: Q8TD30, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (2S)-N-[(1S)-1-(1,3-benzothiazole-2-carbonyl)-4-guanidino-butyl]-3-methyl-2-[[(2S)-2-(3-phenylpropanoylamino)-3-thiazol-4-yl-propanoyl]amino]butanamide
SMILES: CC(C)[C@H](NC(=O)[C@H](Cc1cscn1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)c1nc2ccccc2s1
Target: P09958, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851443
SMILES: COc1ccc(CNS(=O)(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)cc1
Target: Q07889, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: HERNIARIN
SMILES: COc1ccc2ccc(=O)oc2c1
Target: Q9UKU0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(1-(2-chlorobenzyl)piperidin-4-yl)-5-(1H-pyrrol-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-amine
SMILES: Clc1ccccc1CN1CCC(Nc2c(-c3cc[nH]c3)cnc3[nH]ccc23)CC1
Target: TYK2 (P29597), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-methoxyphenyl)acrylate
SMILES: COc1cc(O)c(/C=C\C(=O)O)cc1[C@@H](O)CC(C)C
Target: Q9Y2D0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7975579
SMILES: O=C(Nc1ccc(Cc2ccncc2)cc1)c1ccco1
Target: P22303, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851746
SMILES: CCn1c(COc2ccccc2)nnc1SCC(=O)NC1CCCCC1
Target: Q9NRA2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3711260
SMILES: O=C(COC(=O)CCC1CCCC1)Nc1ccc(Cl)cn1
Target: Q8TAV3, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: LESTAURTINIB
SMILES: C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O
Target: NEK11 (Q8NG66), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: DECERNOTINIB
SMILES: CC[C@@](C)(Nc1ccnc(-c2c[nH]c3ncccc23)n1)C(=O)NCC(F)(F)F
Target: P29466, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (6-((2',4'-Dimethyl-[4,5'-bithiazol]-2-yl)amino)pyridin-3-yl)(7-(5-(trifluoromethyl)pyrimidin-2-yl)-3-oxa-7,9-diazabicyclo[3.3.1]nonan-9-yl)methanone
SMILES: Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5COCC4CN(c4ncc(C(F)(F)F)cn4)C5)cn3)n2)s1
Target: Q8NER1, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4261905
SMILES: O=C(CN1C(=O)c2ccccc2S1(=O)=O)N1CCc2ccccc21
Target: O60885, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 2-(4'-methyl-biphenyl-4-yloxy)-1-morpholin-4-yl-ethanone
SMILES: Cc1ccc(-c2ccc(OCC(=O)N3CCOCC3)cc2)cc1
Target: Q8WWX8, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-hydroxy-2-pivaloylisoindoline-5-carboxamide
SMILES: CC(C)(C)C(=O)N1Cc2ccc(C(=O)NO)cc2C1
Target: O15379, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine
SMILES: CCN(CC)c1ccc(-c2nc3cc(C(=N)N)ccc3[nH]2)c(O)c1
Target: P00742, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: BUTYLPARABEN
SMILES: CCCCOC(=O)c1ccc(O)cc1
Target: P43236, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: [5-(4-Nitrophenyl)-2-furanyl](3,4-dihydro-2(1H)-isoquinolinyl)-Methanone
SMILES: O=C(c1ccc(-c2ccc([N+](=O)[O-])cc2)o1)N1CCc2ccccc2C1
Target: Q08499, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 7-((3-Methoxybenzyl)oxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
SMILES: COc1cccc(COc2ccc3c4c(c(=O)oc3c2)CCC4)c1
Target: Q9NUW8, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4247617
SMILES: Cc1oc2ccc(OCC(N)=O)cc2c1C(=O)OC(C)C
Target: P30405, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-3-(1,3,6-trichloro-9H-carbazol-9-yl)-2-(1,3-dioxoisoindolin-2-yl)propanoic acid
SMILES: O=C(O)[C@H](Cn1c2ccc(Cl)cc2c2cc(Cl)cc(Cl)c21)N1C(=O)c2ccccc2C1=O
Target: P26358, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 5-[3-(dimethylamino)propyl]benzo[c][1]benzazocin-6-one
SMILES: CN(C)CCCN1C(=O)c2ccccc2/C=C\c2ccccc21
Target: P50406, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)-2-(2-fluorophenoxy)acetamide
SMILES: O=C(COc1ccccc1F)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1
Target: P11597, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: TECALCET HYDROCHLORIDE
SMILES: COc1cccc([C@@H](C)NCCCc2ccccc2Cl)c1.Cl
Target: P13945, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7968125
SMILES: Cc1cccc(C2CC(c3ccc(Cl)cc3)Nc3nc(N)nn32)c1
Target: P06870, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID843320
SMILES: CC(=O)N1CCC2(CC1)C(C#N)=C(N)Oc1[nH]nc(C)c12
Target: P35372, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: FLURBIPROFEN
SMILES: CC(C(=O)O)c1ccc(-c2ccccc2)c(F)c1
Target: Q9UKV0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SUNITINIB
SMILES: CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C
Target: Q9NSE4, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: DINACICLIB
SMILES: CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@H]3CCO)nc12
Target: P54619, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (5-amino-3-(pyridin-2-yl)-1H-1,2,4-triazol-1-yl)(4-(4-isopropyl-1,4-diazepan-1-yl)naphthalen-1-yl)methanone
SMILES: CC(C)N1CCCN(c2ccc(C(=O)n3nc(-c4ccccn4)nc3N)c3ccccc23)CC1
Target: P03952, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4254746
SMILES: COC(=O)c1ccc(Nc2nc(C)cc(O)n2)cc1
Target: Q9HBL8, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID26667619
SMILES: COc1ccc(S(=O)(=O)NCC(=O)N(CC(=O)NCC2CCCO2)c2ccccc2C)cc1
Target: Q9Y4X0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)-phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic Acid
SMILES: Cc1nn(C)c(COc2ccc(N3CCN(S(=O)(=O)N(C)C)CC3)cc2)c1-c1cccc2c(CCCOc3cccc4ccccc34)c(C(=O)O)n(CCN3CCOCC3)c12
Target: P10415, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: BMS-777607
SMILES: CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)c2Cl)c(F)c1
Target: MELK (Q14680), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: MK-5108
SMILES: O=C(O)[C@]1(Cc2cccc(Nc3nccs3)n2)CC[C@@H](Oc2cccc(Cl)c2F)CC1
Target: P61073, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: COPANLISIB
SMILES: COc1c(OCCCN2CCOCC2)ccc2c1N=C(NC(=O)c1cnc(N)nc1)N1CCN=C21
Target: P20671, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 3-(benzo[d][1,3]dioxol-5-yl)isoquinolin-7-ol
SMILES: Oc1ccc2cc(-c3ccc4c(c3)OCO4)ncc2c1
Target: P48775, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (R)-3-(((6-(methyl(phenyl)amino)-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)amino)isonicotinic acid
SMILES: CN(c1ccccc1)c1ccc2c(c1)CCC[C@H]2CNc1cnccc1C(=O)O
Target: Q8NFU7, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: TENOXICAM
SMILES: CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O
Target: Q9Y572, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-5-(2-(cyclopropanecarboxamido)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(1-(3-fluorophenyl)ethyl)-1-methyl-1H-indole-3-carboxamide
SMILES: C[C@H](NC(=O)c1cn(C)c2ccc(-c3ccn4nc(NC(=O)C5CC5)nc4c3)cc12)c1cccc(F)c1
Target: RIPK4 (P57078), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID859301
SMILES: Cl.O=C(CCN(CCO)Cc1ccccc1)Nc1ccc(Br)cc1
Target: Q15633, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 6-Isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
SMILES: CC(C)c1c(-c2ccccc2)[nH]c2c(C#N)cnn2c1=O
Target: O43151, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: US9688668, 34
SMILES: CCCCCCCCc1ccc([C@H]2CC[C@H](NC(=N)N)CC2)cc1
Target: Q9NYA1, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-((1-benzyl-4-(naphthalen-1-ylmethyl)piperidin-4-yl)methyl)-3-(piperidin-1-yl)propanamide hydrochloride
SMILES: Cl.O=C(CCN1CCCCC1)NCC1(Cc2cccc3ccccc23)CCN(Cc2ccccc2)CC1
Target: P41143, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3711353
SMILES: O=C(Cc1nnc(O)c2ccccc12)Nc1cccc(-c2nnc3n2CCCCC3)c1
Target: Q6R6M4, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 3-(2-oxo-2-(2-oxo-2H-chromen-3-yl)ethyl)-5-(thiophen-2-ylmethylene)thiazolidine-2,4-dione
SMILES: O=C(CN1C(=O)S/C(=C\c2cccs2)C1=O)c1cc2ccccc2oc1=O
Target: P00918, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID861330
SMILES: C/C(NC1CCCC1)=C(/C#N)C(N)=O
Target: Q8IXJ6, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4252111
SMILES: O=C(CSc1nc2ccsc2c(=O)n1Cc1ccccc1)NCc1ccco1
Target: Q15788, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 7-butyl-8-((4-(3-chlorophenyl)piperazin-1-yl)methyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
SMILES: CCCCn1c(CN2CCN(c3cccc(Cl)c3)CC2)nc2c1c(=O)n(C)c(=O)n2C
Target: O14727, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: TRIACETYLRESVERATROL
SMILES: CC(=O)Oc1ccc(/C=C/c2cc(OC(C)=O)cc(OC(C)=O)c2)cc1
Target: P09960, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-2-(2-amino-4-oxo-3,4-dihydropteridine-7-carboxamido)-3-methylbutanoic acid
SMILES: CC(C)[C@H](NC(=O)c1cnc2c(=O)[nH]c(N)nc2n1)C(=O)O
Target: P15121, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2,2,2-trichloroethyl (1R)-1-(4-bromophenyl)-2-(2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindolin-4-yl)cycloprop-2-ene-1-carboxylate
SMILES: O=C1CCC(N2Cc3cccc(C4=C[C@@]4(C(=O)OCC(Cl)(Cl)Cl)c4ccc(Br)cc4)c3C2=O)C(=O)N1
Target: P15170, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4245126
SMILES: COc1ccc(NC(=O)C2C(=O)NC3(C)CC2c2ccccc2O3)cc1
Target: Q15904, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (E)-N-(3-(2-amino-1H-imidazol-4-yl)allyl)-5-chloro-1H-indole-2-carboxamide
SMILES: Nc1nc(/C=C/CNC(=O)c2cc3cc(Cl)ccc3[nH]2)c[nH]1
Target: P16389, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3712804
SMILES: CCN(CC)c1ccc(C(=O)OCC(=O)N2CCN(c3ccccc3)CC2)cc1
Target: P54253, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4250488
SMILES: COC(=O)C1(S(=O)(=O)c2cccc3nsnc23)CC1
Target: P43490, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4246169
SMILES: O=S(=O)(NCc1csc(-c2cccnc2)n1)c1ccc2c(c1)OCCO2
Target: PAK1 (Q13153), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: TOFACITINIB
SMILES: C[C@@H]1CCN(C(=O)CC#N)C[C@@H]1N(C)c1ncnc2[nH]ccc12
Target: STK16 (O75716), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: ethyl 2-(3,4-dichlorophenyl)-5-hydroxybenzofuran-3-carboxylate
SMILES: CCOC(=O)c1c(-c2ccc(Cl)c(Cl)c2)oc2ccc(O)cc12
Target: P09917, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-1-((2-((3-chloro-4-(thiazol-2-yl)benzyl)oxy)benzyl)(methyl)amino)-3-(methylamino)propan-2-ol
SMILES: CNC[C@H](O)CN(C)Cc1ccccc1OCc1ccc(-c2nccs2)c(Cl)c1
Target: Q9NVM4, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(3-(1-((4-Methyl-4H-1,2,4-triazol-3-yl)thio)ethyl)phenyl)picolinamide
SMILES: CC(Sc1nncn1C)c1cccc(NC(=O)c2ccccn2)c1
Target: Q13191, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID849423
SMILES: COC(=O)Cn1cc(C(=O)c2cccs2)c2ccccc21
Target: Q9Y397, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-((4-((5-chloro-4-(6-phenylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)methyl)-N'-propylbenzohydrazide
SMILES: CCCNNC(=O)c1ccc(Cn2cc(Nc3ncc(Cl)c(-c4cnc5ccc(-c6ccccc6)cn45)n3)cn2)cc1
Target: CDK2 (P24941), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7975579
SMILES: O=C(Nc1ccc(Cc2ccncc2)cc1)c1ccco1
Target: Q9Y314, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: LENIOLISIB
SMILES: CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1
Target: Q92847, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID844691
SMILES: COC(=O)c1ccccc1NC(=O)CN1CCN(C(=O)c2ccco2)CC1
Target: O15527, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (2R)-2-Amino-1-[4-(4-{[5-chloro-4-(pyrazolo[1,5-a]pyridin-3-yl)-2-pyrimidinyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)-1-piperidinyl]-1-propanone
SMILES: Cc1nn(C2CCN(C(=O)[C@@H](C)N)CC2)c(C)c1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1
Target: Q12809, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-1-(1H-benzo[d]imidazol-2-yl)-N-(1-(benzylamino)-5-(2-chloroacetimidamido)-1-oxopentan-2-yl)-9H-pyrido[3,4-b]indole-3-carboxamide
SMILES: N=C(CCl)NCCC[C@H](NC(=O)c1cc2c([nH]c3ccccc32)c(-c2nc3ccccc3[nH]2)n1)C(=O)NCc1ccccc1
Target: Q9Y2J8, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: GALUNISERTIB
SMILES: Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(C(N)=O)cc24)CCC3)n1
Target: MST1R (Q04912), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID849907
SMILES: COc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2C)ccc1NC(=O)c1ccco1
Target: O43598, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-cyclopropyl-3-oxo-N-(4-(pyrimidin-4-ylcarbamoyl)benzyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide
SMILES: O=C1COc2cc(C(=O)N(Cc3ccc(C(=O)Nc4ccncn4)cc3)C3CC3)ccc2N1
Target: O96028, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4242812
SMILES: COc1ccc(C2C(C(=O)N3CCCCC3)CCC(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1
Target: P25098, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-benzylpentanamide
SMILES: CC[C@@H](CC(=O)NCc1ccccc1)n1c(N)nc2cc(Cl)ccc21
Target: P56817, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: R-406
SMILES: COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC
Target: CAMK2B (Q13554), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-isopropylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
SMILES: CC(C)c1nn2cccnc2c1C#N
Target: PIK3CG (P48736), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID843705
SMILES: O=S(=O)(c1ccc(S(=O)(=O)N2CCCC2)cc1)N1CCCCCC1
Target: P62333, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: HYODEOXYCHOLIC_ACID
SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target: P15907, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 5-amino-1-(phenylsulfonyl)-1H-pyrazol-3-yl thiophene-2-carboxylate
SMILES: Nc1cc(OC(=O)c2cccs2)nn1S(=O)(=O)c1ccccc1
Target: P22466, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: APITOLISIB
SMILES: Cc1c(CN2CCN(C(=O)[C@H](C)O)CC2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12
Target: Q02880, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SGC-CLK-1N
SMILES: COc1cc(Nc2nc(C)cc(-c3cnn4nc(OC)ccc34)n2)cc(C(F)(F)F)c1
Target: CLK3 (P49761), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4246169
SMILES: O=S(=O)(NCc1csc(-c2cccnc2)n1)c1ccc2c(c1)OCCO2
Target: Q9RI12, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 7-isopentyl-1,3-dimethyl-8-(morpholinomethyl)-1H-purine-2,6(3H,7H)-dione
SMILES: CC(C)CCn1c(CN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C
Target: P49638, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SUMATRIPTAN
SMILES: CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
Target: O14763, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 6-amino-2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-1,2,4-triazine-3,5(2H,4H)-dione
SMILES: CC(C)c1cc(Oc2c(Cl)cc(-n3nc(N)c(=O)[nH]c3=O)cc2Cl)n[nH]c1=O
Target: P22309, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851856
SMILES: COc1ccc(C(=O)n2nc(-c3ccc(C)cc3)nc2N)cc1OC
Target: P21728, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID843320
SMILES: CC(=O)N1CCC2(CC1)C(C#N)=C(N)Oc1[nH]nc(C)c12
Target: Q9Y237, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: Sapanisertib
SMILES: Cc1nc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2o1
Target: LYN (P07948), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: PSB-11
SMILES: CC[C@@H]1CN2C(=O)N(C)c3nc(-c4ccccc4)[nH]c3C2=N1.Cl
Target: P07550, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID862134
SMILES: C[N+]1=C2c3ccccc3N=CN2CC1.[I-]
Target: O95864, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: BMS-911543
SMILES: CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3cc(C)n(C)n3)nc21
Target: P22466, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (2S,3R)-3-(4-bromophenyl)-2-methyl-3-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}formamido)propanoic acid
SMILES: C[C@H](C(=O)O)[C@@H](NC(=O)c1ncnc2[nH]ccc12)c1ccc(Br)cc1
Target: Q14524, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: PF-04418948
SMILES: COc1ccc2cc(OCC3(C(=O)O)CN(C(=O)c4ccc(F)cc4)C3)ccc2c1
Target: PAK1 (Q13153), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4246687
SMILES: CCOc1ccccc1NS(=O)(=O)c1c(C)noc1C
Target: P42771, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: (E)-3-(4-methoxyphenylimino)indolin-2-one
SMILES: COc1ccc(/N=C2\C(=O)Nc3ccccc32)cc1
Target: P30990, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SID24824251
SMILES: Cc1ccc(C(=O)N[C@@H](C)CN2C3=NC[C@@H](Cc4ccccc4)N3C[C@H]2Cc2ccc(O)cc2)cc1Br
Target: P41143, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 5-Acetamido-9-(butylthioureido)-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid
SMILES: CCCCNC(=S)NC[C@@H](O)[C@@H](O)[C@@H]1OC(C(=O)O)=C[C@H](O)[C@H]1NC(C)=O
Target: Q99519, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: ALECTINIB
SMILES: CCc1cc2c(cc1N1CCC(N3CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
Target: P06737, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4242461
SMILES: O=C(NC1(O)C(=O)c2ccccc2C1=O)c1ccccc1
Target: IKK-epsilon (Q14164), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-Butyl-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine
SMILES: CCCCc1cc(-c2c[nH]c3ncccc23)nc(N)n1
Target: PIK3CB (P42338), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (2R,3S,5R)-5-(1-(cyclopentylsulfonyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-amine
SMILES: N[C@H]1C[C@@H](N2Cc3cnn(S(=O)(=O)C4CCCC4)c3C2)CO[C@@H]1c1cc(F)ccc1F
Target: Q6V1X1, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID859672
SMILES: CCn1cnc2sc(-c3ccccc3)cc2c1=O
Target: P55081, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4240504
SMILES: Cc1ccc(C(C(=O)NC2CCCCC2)N2CCCC2)cc1
Target: O60885, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7973186
SMILES: CN(C)CC(=O)c1ccc(-c2ccccc2)cc1
Target: Q9Y2Q3, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: FAMOTIDINE
SMILES: NC(N)=Nc1nc(CSCC/C(N)=N/S(N)(=O)=O)cs1
Target: Q13574, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4243163
SMILES: COC(=O)c1cc2ccsc2n1CC(=O)Nc1ccc(N(C)C)cc1
Target: P57789, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)acetamide
SMILES: NC(=O)CN1CCCC(c2ccccc2)(C2CCN(Cc3ccc(Br)cc3)CC2)C1
Target: P20309, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: US10849883, Compound 46b::US11559515, Compound 46b
SMILES: NC(=O)c1nn(CC(=O)N(CC(=O)Nc2cccc(OC(F)(F)F)c2)C2CC2)c2ccccc12
Target: P00746, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4255135
SMILES: O=C(CSc1nccc(O)n1)N1CCCc2ccccc21
Target: P50549, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: WHI-P131
SMILES: COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC
Target: B2RXH2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID859672
SMILES: CCn1cnc2sc(-c3ccccc3)cc2c1=O
Target: P10635, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(piperidin-4-yl)-6-(6-(trifluoromethyl)pyridin-3-yl)-1,5-naphthyridin-4-amine
SMILES: FC(F)(F)c1ccc(-c2ccc3nccc(NC4CCNCC4)c3n2)cn1
Target: MAP4K4 (O95819), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 3-(1-methyl-1H-pyrazol-4-yl)-5-((R)-3-methyl-4-((1R,2R)-2-methylcyclopropane-1-carbonyl)piperazin-1-yl)pyrazine-2-carbonitrile
SMILES: C[C@@H]1C[C@H]1C(=O)N1CCN(c2cnc(C#N)c(-c3cnn(C)c3)n2)C[C@H]1C
Target: ERK1 (P27361), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4247617
SMILES: Cc1oc2ccc(OCC(N)=O)cc2c1C(=O)OC(C)C
Target: P05177, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 7-(3-Methyl-5-(2-methyl-5-(piperidin-1-ylmethyl)phenyl)isoxazol-4-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one
SMILES: Cc1ccc(CN2CCCCC2)cc1-c1onc(C)c1-c1ccc2c(c1)OCC(=O)N2
Target: Q9BZ95, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851557
SMILES: CC(C)CC(c1nnnn1CC1CCCO1)N1CCN(C2CCCC2)CC1.Cl
Target: Q15573, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID844691
SMILES: COC(=O)c1ccccc1NC(=O)CN1CCN(C(=O)c2ccco2)CC1
Target: O14727, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: MUBRITINIB
SMILES: FC(F)(F)c1ccc(/C=C/c2nc(COc3ccc(CCCCn4ccnn4)cc3)co2)cc1
Target: O60313, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7978350
SMILES: COC(=O)Cc1cc(O)nc(Nc2nc3ccccc3o2)n1
Target: P52566, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: MOLIBRESIB
SMILES: CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21
Target: PLK1 (P53350), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: TRICIRIBINE PHOSPHATE
SMILES: CN1N=C(N)c2cn([C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O)c3ncnc1c23
Target: IGF1R (P08069), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4255135
SMILES: O=C(CSc1nccc(O)n1)N1CCCc2ccccc21
Target: Q6IN02, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-2-(2-imino-3-(4-methylbenzyl)-6-(trifluoromethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-3-(p-tolyl)propan-1-ol
SMILES: Cc1ccc(C[C@@H](CO)n2c(=N)n(Cc3ccc(C)cc3)c3ccc(C(F)(F)F)cc32)cc1
Target: O43614, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4255287
SMILES: C=CCNC(=O)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc(OC)cc1
Target: P30989, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7967791
SMILES: CCOc1ccc(OCC)c(NC(=O)C2CCCN(S(=O)(=O)c3c[nH]cn3)C2)c1
Target: P98187, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-methyl-5-phenyl-4H-pyrazolo[1,5-a]pyrimidin-7-one
SMILES: Cc1cc2[nH]c(-c3ccccc3)cc(=O)n2n1
Target: Q06609, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: FLURBIPROFEN
SMILES: CC(C(=O)O)c1ccc(-c2ccccc2)c(F)c1
Target: Q8IM16, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 2-(3-amino-1-phenyl-1H-1,2,4-triazol-5-ylthio)-N-methyl-N-phenylacetamide
SMILES: CN(C(=O)CSc1nc(N)nn1-c1ccccc1)c1ccccc1
Target: P32189, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-1-(2-((4-Ethylphenyl)amino)-4-pyrimidinyl)-N-(4-methylbenzyl)-3-piperidinecarboxamide
SMILES: CCc1ccc(Nc2nccc(N3CCC[C@H](C(=O)NCc4ccc(C)cc4)C3)n2)cc1
Target: ALK (Q9UM73), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: ENMD-2076
SMILES: Cc1cc(Nc2cc(N3CCN(C)CC3)nc(/C=C/c3ccccc3)n2)n[nH]1
Target: Q9HD26, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 5-chloro-3-(N-(3,4-diethoxyphenyl)-N-methylsulfamoyl)-N-(3-(methylsulfonyl)phenyl)thiophene-2-carboxamide
SMILES: CCOc1ccc(N(C)S(=O)(=O)c2cc(Cl)sc2C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1OCC
Target: P36956, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (R)-2-cyclohexyl-N-methyl-2-(2-(3-(((S)-5-(pyrimidin-5-yl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)acetamido)acetamide
SMILES: CNC(=O)[C@H](NC(=O)Cc1cccc(O[C@H]2CCc3cc(-c4cncnc4)ccc32)c1)C1CCCCC1
Target: O60609, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 8'-chloro-1'-[trans-4-(2-pyridyloxy)cyclohexyl]spiro[1,3-dioxolane-2,5'-4,6-dihydro-[1,2,4]triazolo[4,3-a][1]benzazepine]
SMILES: Clc1ccc2c(c1)CC1(Cc3nnc([C@H]4CC[C@H](Oc5ccccn5)CC4)n3-2)OCCO1
Target: P10632, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4259590
SMILES: CCn1c(CCNC(=O)c2ccc(Cl)cc2)nnc1SCC(=O)NC1CCCC1
Target: LIMK1 (P53667), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-cyclohexyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide
SMILES: O=C(NC1CCCCC1)c1cc2c(-c3ccccc3)[nH]nc2s1
Target: PLK1 (P53350), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID29215066
SMILES: COc1ccc(-c2nnc(NC(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)o2)cc1
Target: Q08462, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: QAV680
SMILES: Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1
Target: P43119, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 1(5)-(4-bromo-3-methoxyphenyl)-4-thia-2,5,9-triaza-1(2,4)-pyrimidina-3(1,3)-benzenacyclononaphane 4,4-dioxide
SMILES: COc1cc(-c2cnc3nc2NCCCNS(=O)(=O)c2cccc(c2)N3)ccc1Br
Target: ABL1 (P00519), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: DECERNOTINIB
SMILES: CC[C@@](C)(Nc1ccnc(-c2c[nH]c3ncccc23)n1)C(=O)NCC(F)(F)F
Target: P23246, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
SMILES: O=C(O)C1=Cc2cc(Cl)cc(-c3ccc(C(=O)O)cc3)c2OC1C(F)(F)F
Target: P23219, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: LENIOLISIB
SMILES: CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1
Target: P14416, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 5-Bromo-1H-indazole
SMILES: Brc1ccc2[nH]ncc2c1
Target: O14717, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: ETHYLSALVINORINB-2-O-MALONATE
SMILES: CCOC(=O)CC(=O)O[C@H]1C[C@@H](C(=O)OC)[C@]2(C)CC[C@H]3C(=O)O[C@H](c4ccoc4)C[C@]3(C)[C@H]2C1=O
Target: P35372, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-methyl-6-(4-(((3S,5R)-3-methyl-5-(4-methyl-1-oxo-1,3-dihydroisobenzofuran-5-yl)piperazin-1-yl)methyl)-2H-1,2,3-triazol-2-yl)nicotinonitrile
SMILES: Cc1cc(-n2ncc(CN3C[C@@H](c4ccc5c(c4C)COC5=O)N[C@@H](C)C3)n2)ncc1C#N
Target: P78508, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 1-(4-methoxy-phenyl)-7-oxo-6-(2'-pyrrolidin-1-ylmethyl-biphenyl-4-yl)-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid amide
SMILES: COc1ccc(-n2nc(C(N)=O)c3ncn(-c4ccc(-c5ccccc5CN5CCCC5)cc4)c(=O)c32)cc1
Target: P00740, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4257392
SMILES: Cc1cccc(-n2c(SCCC(=O)O)nnc2-c2cccs2)c1C
Target: P29475, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3712804
SMILES: CCN(CC)c1ccc(C(=O)OCC(=O)N2CCN(c3ccccc3)CC2)cc1
Target: Q13535, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SARACATINIB
SMILES: CN1CCN(CCOc2cc(OC3CCOCC3)c3c(Nc4c(Cl)ccc5c4OCO5)ncnc3c2)CC1
Target: Q9UKU0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-(3-((2-(4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-yl)ethyl)amino)phenyl)-2-methylpropanoic acid
SMILES: CC(C)(C(=O)O)c1cccc(CC(O)CN2CCC(=C3c4ccc(Cl)cc4CCc4cccnc43)CC2)c1
Target: P20309, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: US10463675, Example 49::US10980815, Ex. No. 49::US11197867, Example 49::US9663526, Example 49
SMILES: O=C(C1CC1)N1[C@@H]2CC[C@H]1CN(c1ccnc(Nc3cn[nH]c3)n1)C2
Target: JAK3 (P52333), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851942
SMILES: CCc1ccc2nc(SCC(=O)N(CC)CC)c(C#N)cc2c1
Target: C7C422, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: Ethyl (S)-2-((4-(3-Methyl-4-(m-tolyl)piperazine-1-carbonyl)-2-nitrophenyl)thio)acetate
SMILES: CCOC(=O)CSc1ccc(C(=O)N2CCN(c3cccc(C)c3)[C@@H](C)C2)cc1[N+](=O)[O-]
Target: Q99685, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: N-(4-(benzo[d]oxazol-2-yl)phenyl)benzenesulfonamide
SMILES: O=S(=O)(Nc1ccc(-c2nc3ccccc3o2)cc1)c1ccccc1
Target: Q9Y286, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID26667619
SMILES: COc1ccc(S(=O)(=O)NCC(=O)N(CC(=O)NCC2CCCO2)c2ccccc2C)cc1
Target: O15379, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID849018
SMILES: Cc1cccc(-n2c(N)cc(=O)nc2SCC(=O)Nc2cc(C)on2)c1
Target: P51149, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SID49827447
SMILES: Cc1ccnc(NC(=O)Cc2ccc(-c3ccccc3)cc2)c1
Target: Q13285, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: Methyl 4-((2-nitrobenzyl)amino)-1H-indazole-6-carboxylate
SMILES: COC(=O)c1cc(NCc2ccccc2[N+](=O)[O-])c2cn[nH]c2c1
Target: P48775, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4261286
SMILES: O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2
Target: Q6PCT2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxybenzamide
SMILES: O=C(NO)c1ccc(CN2CCCc3ccccc32)cc1
Target: Q13547, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: [2-(3-fluorophenyl)-1,3-oxazol-4-yl](1H-pyrazol-1-yl)methanone
SMILES: O=C(c1coc(-c2cccc(F)c2)n1)n1cccn1
Target: Q07343, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: SID57263403
SMILES: COc1ccccc1NC(=O)COC(=O)c1cc2c(s1)CCC2
Target: Q9HC16, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: NOVOBIOCIN
SMILES: CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C
Target: O75417, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4245574
SMILES: CCC(Sc1nc(C)cc(O)n1)C(=O)Nc1nc2c(s1)CCCC2
Target: P08485, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7975041
SMILES: CNC(=O)C(Sc1ccccc1)c1ccccc1
Target: Q9R0C9, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(2-((S)-2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)-6-(3-fluoro-2-methoxypropoxy)quinoline-4-carboxamide
SMILES: COC(CF)COc1ccc2nccc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)c2c1
Target: Q9UHL4, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: JNJ-38877605
SMILES: Cn1cc(-c2ccc3nnc(C(F)(F)c4ccc5ncccc5c4)n3n2)cn1
Target: Q9UPW6, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3715063
SMILES: O=C(Cn1nnc(-c2ccccc2)n1)OCc1csc(-c2ccccc2)n1
Target: O15439, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(5-(4-Isopropylpiperazin-1-yl)pentyl)-6,7-dimethoxy-2-(pyrrolidin-1-yl)quinazolin-4-amine
SMILES: COc1cc2nc(N3CCCC3)nc(NCCCCCN3CCN(C(C)C)CC3)c2cc1OC
Target: Q9NQR1, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4254567
SMILES: COc1cccc2cc(C(=O)NCC3CCCO3)c(=O)oc12
Target: O75874, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7976733
SMILES: CC(C)=CCC/C(C)=C/CC/C(C)=N/O
Target: CDK9 (P50750), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID24839062
SMILES: Cc1ccc(N2C(=O)Nc3ccc(Br)cc3C2(O)C(=O)NCCCN(C)C)cc1C
Target: O00625, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: FOSTAMATINIB
SMILES: COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)N(COP(=O)(O)O)C(=O)C(C)(C)O4)n2)cc(OC)c1OC
Target: A6NNZ2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4259590
SMILES: CCn1c(CCNC(=O)c2ccc(Cl)cc2)nnc1SCC(=O)NC1CCCC1
Target: P21439, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: CHLORAMBUCIL
SMILES: O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1
Target: Q9Y2K6, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID850754
SMILES: COCCCn1c(SCC(=O)OC2CCCCC2)nnc1-c1ccco1
Target: Q7L8S5, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: FANANSERIN
SMILES: O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2ccc(F)cc2)CC1
Target: P23975, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-Phenyl-3H-indol-3-one 1-Oxide
SMILES: O=C1C(c2ccccc2)=[N+]([O-])c2ccccc21
Target: O14727, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4250224
SMILES: CCS(=O)(=O)N1CCC(C(=O)NCc2ccc(F)cc2Cl)CC1
Target: Q08257, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N7-butyl-3-ethyl-1-{[3-methoxy-5-(piperidin-4-yl)pyridin-2-yl]methyl}-1H-pyrazolo[4,3-d]pyrimidine-5,7-diamine
SMILES: CCCCNc1nc(N)nc2c(CC)nn(Cc3ncc(C4CCNCC4)cc3OC)c12
Target: Q12809, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 7-pentyl-8-(phenethylthio)-3,7-dihydro-1H-purine-2,6-dione
SMILES: CCCCCn1c(SCCc2ccccc2)nc2[nH]c(=O)[nH]c(=O)c21
Target: Q9HC29, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: RIVASTIGMINE
SMILES: CCN(C)C(=O)Oc1cccc([C@H](C)N(C)C)c1
Target: P27338, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID846908
SMILES: O=C(NCc1cccc(C(F)(F)F)c1)C1CCCN(c2ncccn2)C1
Target: P29965, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: AFATINIB
SMILES: CN(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1
Target: P30519, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-(4-((4-(dimethylamino)phenyl)amino)quinazolin-2-yl)-2-fluorobenzonitrile
SMILES: CN(C)c1ccc(Nc2nc(-c3ccc(C#N)c(F)c3)nc3ccccc23)cc1
Target: O60341, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 9-cyclopropyl-N-methyl-9H-purin-6-amine
SMILES: CNc1ncnc2c1ncn2C1CC1
Target: Q96MU7, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 3-(4-methoxyphenyl)-7-((2,4,6-trimethylbenzyl)oxy)-4H-chromen-4-one
SMILES: COc1ccc(C2COc3cc(OCc4c(C)cc(C)cc4C)ccc3C2=O)cc1
Target: Q9HBA0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7974904
SMILES: CC(C(=O)NCc1ccccn1)N1C(=O)c2ccccc2C1=O
Target: O14880, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3717342
SMILES: COc1ccc(C(C)=O)cc1COC(=O)c1cc(C)oc1C
Target: O14607, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: MELATONIN
SMILES: COc1ccc2[nH]cc(CCNC(C)=O)c2c1
Target: Q99836, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: (E)-3-(4-methoxyphenylimino)indolin-2-one
SMILES: COc1ccc(/N=C2\C(=O)Nc3ccccc32)cc1
Target: P35367, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: UCN-01
SMILES: CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)N[C@H]4O
Target: CSNK1G2 (P78368), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-N-(4-(((2S,5R)-5-((R)-Hydroxy(phenyl)methyl)pyrrolidin-2-yl)-methyl)phenyl)-2-(6-oxopyridazin-1(6H)-yl)propanamide
SMILES: C[C@@H](C(=O)Nc1ccc(C[C@@H]2CC[C@H]([C@H](O)c3ccccc3)N2)cc1)n1ncccc1=O
Target: Q14524, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4256641
SMILES: COc1ccc(-c2nnc(NC(=O)c3cc(C)on3)s2)cc1
Target: Q15366, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID849018
SMILES: Cc1cccc(-n2c(N)cc(=O)nc2SCC(=O)Nc2cc(C)on2)c1
Target: P28222, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 7-isopentyl-1,3-dimethyl-8-(morpholinomethyl)-1H-purine-2,6(3H,7H)-dione
SMILES: CC(C)CCn1c(CN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C
Target: PAK1 (Q13153), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-(5-((4-(Tertbutyl)phenyl)amino)pyridin-3-yl)-2-hydroxybenzoic acid
SMILES: CC(C)(C)c1ccc(Nc2cncc(-c3ccc(C(=O)O)c(O)c3)c2)cc1
Target: Q96S37, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: CHLORAMBUCIL
SMILES: O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1
Target: JAK1 (P23458), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: ACETARSONE
SMILES: CC(=O)Nc1cc([As](=O)(O)O)ccc1O
Target: Q8NBQ5, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID844654
SMILES: O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccnc1)c1ccco1
Target: Q96KB5, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: XL-019
SMILES: O=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)C1CCCN1
Target: MAPKAPK5 (Q8IW41), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID862134
SMILES: C[N+]1=C2c3ccccc3N=CN2CC1.[I-]
Target: Q00534, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7974486
SMILES: COc1cc(OC)cc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)c1
Target: Q9H7Z6, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 3-(8-(3-phenylpropyl)-3,8-diazabicyclo[3.2.1]octan-3-yl)phenol
SMILES: Oc1cccc(N2C[C@H]3CC[C@@H](C2)N3CCCc2ccccc2)c1
Target: P41145, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(1H-benzo[d]imidazol-6-yl)-2-(4-bromophenoxy)acetamide
SMILES: O=C(COc1ccc(Br)cc1)Nc1ccc2nc[nH]c2c1
Target: Q9H244, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4256969
SMILES: Oc1cccc(C(=S)N2CCN(Cc3ccccc3)CC2)c1
Target: P18031, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (S)-5-(2-(cyclopropanecarboxamido)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(1-(3-fluorophenyl)ethyl)-1-methyl-1H-indole-3-carboxamide
SMILES: C[C@H](NC(=O)c1cn(C)c2ccc(-c3ccn4nc(NC(=O)C5CC5)nc4c3)cc12)c1cccc(F)c1
Target: Q9Y572, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7972262
SMILES: COC(=O)COc1ccc2c(=O)c(Oc3ccccc3)c(C)oc2c1
Target: P14416, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: Ac-Lys(N-epsilon-biotinoyl)-Ala-Ala-Nal-Thr(PO3H2)-Pro-tBuGly-Gln-NH2
SMILES: CC(=O)N[C@@H](CCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(N)=O)C(C)(C)C)[C@H](C)OP(=O)(O)O
Target: Q13526, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: PENTOXIFYLLINE
SMILES: CC(=O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O
Target: P41586, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(3-(benzyl(propyl)amino)propyl)-5-phenylthiophene-2-carboxamide
SMILES: CCCN(CCCNC(=O)c1ccc(-c2ccccc2)s1)Cc1ccccc1
Target: P61073, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7967769
SMILES: CCN(CC)S(=O)(=O)c1ccc(-c2nnc3sc4cccc(C)c4n23)cc1
Target: Q9HD36, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: VARLITINIB
SMILES: C[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1
Target: PAK4 (O96013), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 5-(N-ETHYL-N-ISOPROPYL)AMILORIDE
SMILES: CCN(c1nc(N)c(C(=O)NC(=N)N)nc1Cl)C(C)C
Target: O95264, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 6-(pyridin-3-yl)-1H-benzo[d]imidazole
SMILES: c1cncc(-c2ccc3nc[nH]c3c2)c1
Target: Q16769, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2,4-dimethyl-N-(1-(pyridin-3-yl)azetidin-3-yl)-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxamide
SMILES: Cc1cc(C)c2c(n1)CN(C(=O)NC1CN(c3cccnc3)C1)C2
Target: P08172, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID852593
SMILES: C=CCn1c(N)cc(=O)nc1SCC(=O)Nc1ccccc1
Target: P28222, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: (R)-2-acetoxy-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
SMILES: CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(C)=O
Target: P18089, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: US11584714, Compound 1091
SMILES: C[C@H](NC(=O)[C@H](N)C1Cc2ccccc2C1)C(=O)NCc1ccc2nc(N)ccc2c1
Target: Q9UJ71, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 2-(3,4-bis(4-(benzyloxy)phenyl)isoxazol-5-yl)acetic acid
SMILES: O=C(O)Cc1onc(-c2ccc(OCc3ccccc3)cc2)c1-c1ccc(OCc2ccccc2)cc1
Target: P35354, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: methyl 2-(4-fluorophenyl)-4-((4-(1-methyl-1H-imidazole-2-carbonyl)phenyl)amino)-4-oxobutanoate
SMILES: COC(=O)C(CC(=O)Nc1ccc(C(=O)c2nccn2C)cc1)c1ccc(F)cc1
Target: P00338, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-Neopentyl-4-(1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)pyrimidin-2-amine Bis(2,2,2-trifluoroacetate)
SMILES: CC(C)(C)CNc1nccc(N2CCc3nc[nH]c3C2)n1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Target: P25021, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3711260
SMILES: O=C(COC(=O)CCC1CCCC1)Nc1ccc(Cl)cn1
Target: O75469, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 10-(4-chlorophenyl)-7-(trifluoromethyl)-10Hpyrimido[4,5-b]quinoline-2,4-dione
SMILES: O=c1nc2n(-c3ccc(Cl)cc3)c3ccc(C(F)(F)F)cc3cc-2c(=O)[nH]1
Target: Q00987, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: PALBOCICLIB
SMILES: CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O
Target: P78325, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-((S)-1-(((1R,2R)-2-(benzyloxy)-1-cyanopropyl)amino)-3-(3-chlorophenyl)-1-oxopropan-2-yl)-[1,1'-biphenyl]-3-carboxamide
SMILES: C[C@@H](OCc1ccccc1)[C@@H](C#N)NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)c1cccc(-c2ccccc2)c1
Target: P43235, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: MOLIBRESIB
SMILES: CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21
Target: Q13183, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4264299
SMILES: COc1ccc(OCC(=O)Nc2cccc3ncccc23)cc1
Target: Q9NXB9, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4256969
SMILES: Oc1cccc(C(=S)N2CCN(Cc3ccccc3)CC2)c1
Target: Q6ZWH5, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: MK 1903
SMILES: O=C(O)c1n[nH]c2c1C[C@H]1C[C@@H]21
Target: P47898, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acid
SMILES: O=C(O)CCCCCC[C@@H]1[C@@H](CCC(O)CSc2ccccc2)[C@H](O)C[C@@H]1O
Target: P21731, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 6-Methyl-3-(3-phenyl-1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
SMILES: CC1=Nn2c(nnc2-c2cc(-c3ccccc3)[nH]n2)SC1
Target: P00374, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID849423
SMILES: COC(=O)Cn1cc(C(=O)c2cccs2)c2ccccc21
Target: TAOK1 (Q7L7X3), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 5-(5-Methanesulfonyl-2-{[(2S)-1,1,1-trifluoropropan-2-yl]-oxy}benzoyl)-2-(3-methylphenyl)-2H,4H,5H,6H-pyrrolo[3,4-c]-pyrazole
SMILES: Cc1cccc(-n2cc3c(n2)CN(C(=O)c2cc(S(C)(=O)=O)ccc2O[C@@H](C)C(F)(F)F)C3)c1
Target: P05177, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 5-(N-ETHYL-N-ISOPROPYL)AMILORIDE
SMILES: CCN(c1nc(N)c(C(=O)NC(=N)N)nc1Cl)C(C)C
Target: ERN1 (O75460), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-{[(1R)-1-(4-Chlorophenyl)ethyl]amino}-6-(3-pyridinyl)-3-quinolinecarboxylic acid
SMILES: C[C@@H](Nc1c(C(=O)O)cnc2ccc(-c3cccnc3)cc12)c1ccc(Cl)cc1
Target: Q13535, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 3-methylglutarimide
SMILES: CC1CC(=O)NC(=O)C1
Target: Q96SW2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: Eugenine
SMILES: CCO[C@H]1O[C@@H]2CC=C3CCN(C)[C@H]3[C@@H]2c2cc(OC)c(O)cc21
Target: P22303, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-(3-(Dimethylamino)propoxy)-N-(2-(4-(trifluoromethyl)phenoxy)phenyl)benzenesulfonamide
SMILES: CN(C)CCCOc1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(C(F)(F)F)cc2)cc1
Target: O95180, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: ENMD-2076
SMILES: Cc1cc(Nc2cc(N3CCN(C)CC3)nc(/C=C/c3ccccc3)n2)n[nH]1
Target: Q96RG2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID846908
SMILES: O=C(NCc1cccc(C(F)(F)F)c1)C1CCCN(c2ncccn2)C1
Target: O00459, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: NODULISPORONE
SMILES: COc1cccc2c1C(=O)CCC2O
Target: Q9UGP5, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: GSK-1904529A
SMILES: CCc1cc(Nc2nccc(-c3c(-c4ccc(OC)c(C(=O)Nc5c(F)cccc5F)c4)nc4ccccn34)n2)c(OC)cc1N1CCC(N2CCN(S(C)(=O)=O)CC2)CC1
Target: S6K1 (P23443), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID850986
SMILES: CC1Oc2ccccc2N(Cc2ccccc2Cl)C1=O
Target: Q9H0C8, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID3717342
SMILES: COc1ccc(C(C)=O)cc1COC(=O)c1cc(C)oc1C
Target: P98073, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 4-(6-carbamoyl-9-(4-nitrophenyl)-8-oxo-8,9-dihydro-7H-purin-2-yl)benzoic acid
SMILES: NC(=O)c1nc(-c2ccc(C(=O)O)cc2)nc2c1[nH]c(=O)n2-c1ccc([N+](=O)[O-])cc1
Target: CSNK2A1 (P68400), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: GLUTAMIC ACID
SMILES: N[C@@H](CCC(=O)O)C(=O)O
Target: P42263, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: 1-(4-((3,4-Dichlorobenzyl)oxy)benzyl)azetidine-3-carboxylic Acid
SMILES: O=C(O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C1
Target: Q9NR56, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 1-(3-chlorophenyl)-4-((2-fluorophenyl)(2-isopropylphenyl)methyl)piperazine
SMILES: CC(C)c1ccccc1C(c1ccccc1F)N1CCN(c2cccc(Cl)c2)CC1
Target: Q8IZK6, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID24840484
SMILES: Cc1sc2nc(CSc3nnc(Cc4cccs4)n3C3CCCCC3)nc(O)c2c1C
Target: Q9NXA8, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: US10689376, Compound 35::US11142524, Compound 35
SMILES: COc1ccc(NC(=O)CSc2nc3cnc(Cl)cc3[nH]2)cc1OC(F)(F)F
Target: P22413, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: MMV299572
SMILES: O=C(NCc1nc2cc(Br)c[nH]c-2n1)c1ccccc1
Target: Q9UBS0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID26513958
SMILES: O=C1C2C3C=CC(C3)C2C(=O)N1c1n[nH]c(CCc2ccccc2)n1
Target: Q9GZT9, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: JNJ-38877605
SMILES: Cn1cc(-c2ccc3nnc(C(F)(F)c4ccc5ncccc5c4)n3n2)cn1
Target: P30305, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID24840484
SMILES: Cc1sc2nc(CSc3nnc(Cc4cccs4)n3C3CCCCC3)nc(O)c2c1C
Target: Q15363, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: DACOMITINIB ANHYDROUS
SMILES: COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1CCCCC1
Target: CLK3 (P49761), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID851746
SMILES: CCn1c(COc2ccccc2)nnc1SCC(=O)NC1CCCCC1
Target: Q96RU2, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4256458
SMILES: OCc1nc2ccccc2n1CC(O)Cn1ccc2ccccc21
Target: Q96GG9, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID4261411
SMILES: O=C(CN1C(=O)CSc2ccccc21)N1CCc2ccccc21
Target: O60361, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: LENIOLISIB
SMILES: CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1
Target: P08908, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID24839062
SMILES: Cc1ccc(N2C(=O)Nc3ccc(Br)cc3C2(O)C(=O)NCCCN(C)C)cc1C
Target: Q8NER1, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-morpholinoacetamide
SMILES: N#Cc1c(NC(=O)CN2CCOCC2)sc2c1CCCC2
Target: JNK3 (P53779), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: BAY-0361
SMILES: CC[C@H](Nc1c(C#N)c(-c2ccc(-c3cccc(C)c3F)cc2)nc2cnccc12)C(=O)O
Target: P48426, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: N-((1r,4r)-4-(5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)cyclohexyl)acetamide
SMILES: CC(=O)N[C@H]1CC[C@H](c2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)CC1
Target: TEC (P42680), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: tested

Compound: 9-(benzo[d][1,3]dioxol-5-yl)-2-fluoro-5-(2-hydroxyethyl)-8-methoxyphenanthridin-5-ium bromide
SMILES: COc1cc2c[n+](CCO)c3ccc(F)cc3c2cc1-c1ccc2c(c1)OCO2.[Br-]
Target: P35813, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID861956
SMILES: CC(C)OC(=O)CSc1nnc(-c2cccnc2)n1N
Target: Q9ULW0, protein

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested


Answer: untested

Compound: SID7973186
SMILES: CN(C)CC(=O)c1ccc(-c2ccccc2)cc1
Target: p38-alpha (Q16539), kinase

Has this compound-target pair been experimentally tested for interaction?
If tested, provide the source (database, assay ID, or publication).

Answer: tested / untested