diff --git "a/data/ppi_llm/ppi_l2_dataset.jsonl" "b/data/ppi_llm/ppi_l2_dataset.jsonl"
new file mode 100644--- /dev/null
+++ "b/data/ppi_llm/ppi_l2_dataset.jsonl"
@@ -0,0 +1,500 @@
+{"question_id": "PPIL2-0000", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT3 and TOMM40: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT3", "protein_2": "TOMM40", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1483666], "include_positive": false}}
+{"question_id": "PPIL2-0001", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CASP8 and AP1S2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CASP8", "protein_2": "AP1S2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1404920], "include_positive": false}}
+{"question_id": "PPIL2-0002", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- INTS3 and CHMP7: no interaction detected\n- HUS1 and KAT5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "INTS3", "protein_2": "CHMP7", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HUS1", "protein_2": "KAT5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [899764, 518631], "include_positive": false}}
+{"question_id": "PPIL2-0003", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ERGIC3 and ITFG2: no interaction detected\n- NLGN3 and CDC25B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ERGIC3", "protein_2": "ITFG2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NLGN3", "protein_2": "CDC25B", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [610492, 1942430], "include_positive": false}}
+{"question_id": "PPIL2-0004", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COLEC11 and SRPRA: no interaction detected\n- PRKCZ and AURKB: no interaction detected\n- IFNLR1 and NLGN1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COLEC11", "protein_2": "SRPRA", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PRKCZ", "protein_2": "AURKB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "IFNLR1", "protein_2": "NLGN1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1476040, 968042, 1032325], "include_positive": false}}
+{"question_id": "PPIL2-0005", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RIPPLY3 and PDE4DIP: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RIPPLY3", "protein_2": "PDE4DIP", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2001239], "include_positive": true}}
+{"question_id": "PPIL2-0006", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SFMBT2 and NREP: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SFMBT2", "protein_2": "NREP", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2066283], "include_positive": false}}
+{"question_id": "PPIL2-0007", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- AGA and DYNC2I2: no interaction detected\n- DNALI1 and HSD17B13: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AGA", "protein_2": "DYNC2I2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "DNALI1", "protein_2": "HSD17B13", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1924546, 1793538], "include_positive": false}}
+{"question_id": "PPIL2-0008", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DDX6 and SUPV3L1: no interaction detected\n- ASCC1 and S100A8: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DDX6", "protein_2": "SUPV3L1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ASCC1", "protein_2": "S100A8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [981842, 1124053], "include_positive": false}}
+{"question_id": "PPIL2-0009", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RXRB and MNAT1: no interaction detected\n- CKMT2 and MYDGF: no interaction detected\n- ELP6 and IFNG: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RXRB", "protein_2": "MNAT1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CKMT2", "protein_2": "MYDGF", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "ELP6", "protein_2": "IFNG", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1194326, 172168, 1184016], "include_positive": true}}
+{"question_id": "PPIL2-0010", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SRPRB and SRCAP: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SRPRB", "protein_2": "SRCAP", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1677912], "include_positive": true}}
+{"question_id": "PPIL2-0011", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- KHDRBS3 and CIITA: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KHDRBS3", "protein_2": "CIITA", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1838544], "include_positive": false}}
+{"question_id": "PPIL2-0012", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TRAF2 and ARL6IP1: no interaction detected\n- LAMA3 and CENPW: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRAF2", "protein_2": "ARL6IP1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "LAMA3", "protein_2": "CENPW", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [289862, 1343554], "include_positive": false}}
+{"question_id": "PPIL2-0013", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ITGB7 and FRAT2: no interaction detected\n- WDR82 and DCAF8L2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ITGB7", "protein_2": "FRAT2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "WDR82", "protein_2": "DCAF8L2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [511005, 1893089], "include_positive": true}}
+{"question_id": "PPIL2-0014", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- OPN1MW2 and IL27: no interaction detected\n- PRR5 and CHMP2B: no interaction detected\n- STMN1 and SYNPO2L: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "OPN1MW2", "protein_2": "IL27", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PRR5", "protein_2": "CHMP2B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "STMN1", "protein_2": "SYNPO2L", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1897430, 731429, 169874], "include_positive": false}}
+{"question_id": "PPIL2-0015", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- EVA1A and DLGAP4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EVA1A", "protein_2": "DLGAP4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [488985], "include_positive": false}}
+{"question_id": "PPIL2-0016", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- AKAP7 and ARMCX3: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AKAP7", "protein_2": "ARMCX3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [65706], "include_positive": false}}
+{"question_id": "PPIL2-0017", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SSX3 and UNG: no interaction detected\n- ALOX15B and SLC23A3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SSX3", "protein_2": "UNG", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ALOX15B", "protein_2": "SLC23A3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1905673, 1804666], "include_positive": true}}
+{"question_id": "PPIL2-0018", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TRAPPC13 and APC: no interaction detected\n- KIF3C and TRAPPC2L: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRAPPC13", "protein_2": "APC", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KIF3C", "protein_2": "TRAPPC2L", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1006554, 579739], "include_positive": true}}
+{"question_id": "PPIL2-0019", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PDGFRB and MCM2: no interaction detected\n- IFNG and ATF7-NPFF: no interaction detected\n- MCOLN2 and FAM193A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PDGFRB", "protein_2": "MCM2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "IFNG", "protein_2": "ATF7-NPFF", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MCOLN2", "protein_2": "FAM193A", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [742207, 1780340, 2013539], "include_positive": false}}
+{"question_id": "PPIL2-0020", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ITGAV and RPA3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ITGAV", "protein_2": "RPA3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [758923], "include_positive": true}}
+{"question_id": "PPIL2-0021", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CHST13 and ATP6V0B: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHST13", "protein_2": "ATP6V0B", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [428499], "include_positive": true}}
+{"question_id": "PPIL2-0022", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- DESI1 and WDR73: no interaction detected\n- ADIPOR2 and HMGB4: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DESI1", "protein_2": "WDR73", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ADIPOR2", "protein_2": "HMGB4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2109301, 2144479], "include_positive": false}}
+{"question_id": "PPIL2-0023", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TNFRSF9 and PGLYRP2: no interaction detected\n- UGP2 and CCDC158: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TNFRSF9", "protein_2": "PGLYRP2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "UGP2", "protein_2": "CCDC158", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [282141, 327220], "include_positive": false}}
+{"question_id": "PPIL2-0024", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT2 and DYNC1LI2: no interaction detected\n- CELF6 and LYAR: no interaction detected\n- CFAP44 and GKN1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT2", "protein_2": "DYNC1LI2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CELF6", "protein_2": "LYAR", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CFAP44", "protein_2": "GKN1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1296717, 461742, 466308], "include_positive": true}}
+{"question_id": "PPIL2-0025", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PLCB4 and LRRC40: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PLCB4", "protein_2": "LRRC40", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [314431], "include_positive": true}}
+{"question_id": "PPIL2-0026", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- MRPS14 and GOLGA8T: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MRPS14", "protein_2": "GOLGA8T", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1776890], "include_positive": true}}
+{"question_id": "PPIL2-0027", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PTCD3 and TOMM22: no interaction detected\n- VPS37A and AXIN2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PTCD3", "protein_2": "TOMM22", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "VPS37A", "protein_2": "AXIN2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1627938, 559008], "include_positive": true}}
+{"question_id": "PPIL2-0028", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SDC1 and RPL36A: no interaction detected\n- HOXB7 and SLC36A1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SDC1", "protein_2": "RPL36A", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "HOXB7", "protein_2": "SLC36A1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1919379, 145510], "include_positive": false}}
+{"question_id": "PPIL2-0029", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- UBA2 and CPSF2: no interaction detected\n- BLOC1S2 and HAUS6: no interaction detected\n- VAMP1 and MACROH2A2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "UBA2", "protein_2": "CPSF2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "BLOC1S2", "protein_2": "HAUS6", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "VAMP1", "protein_2": "MACROH2A2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1275261, 645437, 185804], "include_positive": false}}
+{"question_id": "PPIL2-0030", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- RPL7L1 and ZNF692: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RPL7L1", "protein_2": "ZNF692", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [361954], "include_positive": false}}
+{"question_id": "PPIL2-0031", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP5MJ and WDR5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP5MJ", "protein_2": "WDR5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [751125], "include_positive": false}}
+{"question_id": "PPIL2-0032", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SCT and BMERB1: no interaction detected\n- HEXB and CFB: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SCT", "protein_2": "BMERB1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "HEXB", "protein_2": "CFB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [145937, 771257], "include_positive": false}}
+{"question_id": "PPIL2-0033", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- YIPF1 and CYYR1: no interaction detected\n- FANCA and ARID1B: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "YIPF1", "protein_2": "CYYR1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "FANCA", "protein_2": "ARID1B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2206106, 679512], "include_positive": true}}
+{"question_id": "PPIL2-0034", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GPAA1 and ABCA8: no interaction detected\n- CDK13 and JAK2: no interaction detected\n- MYB and BBS5: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GPAA1", "protein_2": "ABCA8", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CDK13", "protein_2": "JAK2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MYB", "protein_2": "BBS5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1810995, 1234995, 797710], "include_positive": false}}
+{"question_id": "PPIL2-0035", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BCL2L1 and ATF2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BCL2L1", "protein_2": "ATF2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1185026], "include_positive": false}}
+{"question_id": "PPIL2-0036", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ZFR and SOS2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZFR", "protein_2": "SOS2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2030167], "include_positive": false}}
+{"question_id": "PPIL2-0037", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RNH1 and CBX8: no interaction detected\n- GTF2H5 and ZNF329: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNH1", "protein_2": "CBX8", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "GTF2H5", "protein_2": "ZNF329", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1906260, 383148], "include_positive": true}}
+{"question_id": "PPIL2-0038", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- KRTAP5-9 and TRIB3: no interaction detected\n- PRIM1 and COMMD3: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KRTAP5-9", "protein_2": "TRIB3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PRIM1", "protein_2": "COMMD3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [189676, 227372], "include_positive": false}}
+{"question_id": "PPIL2-0039", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SCRIB and TIMM29: no interaction detected\n- DDOST and PDHB: no interaction detected\n- IFT122 and SUCLG1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SCRIB", "protein_2": "TIMM29", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DDOST", "protein_2": "PDHB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "IFT122", "protein_2": "SUCLG1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1231347, 680863, 1045172], "include_positive": false}}
+{"question_id": "PPIL2-0040", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TSPAN8 and TBPL1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSPAN8", "protein_2": "TBPL1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [174938], "include_positive": false}}
+{"question_id": "PPIL2-0041", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- IL7R and NEK3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IL7R", "protein_2": "NEK3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1914606], "include_positive": true}}
+{"question_id": "PPIL2-0042", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMARCC1 and ARID4A: no interaction detected\n- CBX3 and DLG5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMARCC1", "protein_2": "ARID4A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CBX3", "protein_2": "DLG5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1076761, 545028], "include_positive": false}}
+{"question_id": "PPIL2-0043", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DLD and SOS1: no interaction detected\n- KLRC2 and PIGM: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DLD", "protein_2": "SOS1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KLRC2", "protein_2": "PIGM", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [790124, 1491752], "include_positive": false}}
+{"question_id": "PPIL2-0044", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GRIN3A and WRAP73: no interaction detected\n- EIF3A and PATJ: no interaction detected\n- ZNF19 and PNMA5: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GRIN3A", "protein_2": "WRAP73", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "EIF3A", "protein_2": "PATJ", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZNF19", "protein_2": "PNMA5", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2184573, 1469125, 170333], "include_positive": false}}
+{"question_id": "PPIL2-0045", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- HACD1 and MOB3B: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HACD1", "protein_2": "MOB3B", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [19306], "include_positive": false}}
+{"question_id": "PPIL2-0046", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- BLK and DEPTOR: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BLK", "protein_2": "DEPTOR", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [233352], "include_positive": true}}
+{"question_id": "PPIL2-0047", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PSEN1 and POLE3: no interaction detected\n- SARNP and IGHG4: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PSEN1", "protein_2": "POLE3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SARNP", "protein_2": "IGHG4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1597791, 585771], "include_positive": true}}
+{"question_id": "PPIL2-0048", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SKIL and ZIC5: no interaction detected\n- CCDC51 and CYSLTR2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SKIL", "protein_2": "ZIC5", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CCDC51", "protein_2": "CYSLTR2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1905047, 457459], "include_positive": false}}
+{"question_id": "PPIL2-0049", "task": "ppi-l2", "split": "fewshot", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- FAM3C and ELMO1: no interaction detected\n- CCNC and CDC20: no interaction detected\n- F10 and MED17: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FAM3C", "protein_2": "ELMO1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CCNC", "protein_2": "CDC20", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "F10", "protein_2": "MED17", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [444920, 655286, 605368], "include_positive": false}}
+{"question_id": "PPIL2-0050", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATF4 and BMAL1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATF4", "protein_2": "BMAL1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1189061], "include_positive": true}}
+{"question_id": "PPIL2-0051", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- FLT4 and KLRG2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FLT4", "protein_2": "KLRG2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1741817], "include_positive": false}}
+{"question_id": "PPIL2-0052", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CCSER1 and DNAJC8: no interaction detected\n- ZP3 and LRSAM1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CCSER1", "protein_2": "DNAJC8", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ZP3", "protein_2": "LRSAM1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1844604, 180801], "include_positive": false}}
+{"question_id": "PPIL2-0053", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- KIAA1143 and AP3S1: no interaction detected\n- REL and PRKAA1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KIAA1143", "protein_2": "AP3S1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "REL", "protein_2": "PRKAA1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2193812, 1195257], "include_positive": true}}
+{"question_id": "PPIL2-0054", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- NCS1 and TMEM254: no interaction detected\n- NR1H2 and KCND3: no interaction detected\n- APH1B and FARSA: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NCS1", "protein_2": "TMEM254", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "NR1H2", "protein_2": "KCND3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "APH1B", "protein_2": "FARSA", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2009531, 866646, 1166400], "include_positive": false}}
+{"question_id": "PPIL2-0055", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SIPA1L3 and C2CD4A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SIPA1L3", "protein_2": "C2CD4A", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1821820], "include_positive": false}}
+{"question_id": "PPIL2-0056", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- EIF4EBP3 and USF2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EIF4EBP3", "protein_2": "USF2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [74929], "include_positive": false}}
+{"question_id": "PPIL2-0057", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NFIL3 and CEP152: no interaction detected\n- UBE2V1 and GABBR1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NFIL3", "protein_2": "CEP152", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "UBE2V1", "protein_2": "GABBR1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [976132, 1252770], "include_positive": false}}
+{"question_id": "PPIL2-0058", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LDHA and HTR3C: no interaction detected\n- MTX2 and EDC4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LDHA", "protein_2": "HTR3C", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MTX2", "protein_2": "EDC4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [502101, 702084], "include_positive": false}}
+{"question_id": "PPIL2-0059", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- DEPTOR and SETDB2: no interaction detected\n- ATG14 and GUCY2C: no interaction detected\n- VPS39 and SIRT1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DEPTOR", "protein_2": "SETDB2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ATG14", "protein_2": "GUCY2C", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "VPS39", "protein_2": "SIRT1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2182622, 1933416, 810315], "include_positive": true}}
+{"question_id": "PPIL2-0060", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ZNF84 and PPP6R1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZNF84", "protein_2": "PPP6R1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1987909], "include_positive": false}}
+{"question_id": "PPIL2-0061", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ITGA6 and PRKCSH: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ITGA6", "protein_2": "PRKCSH", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [960362], "include_positive": true}}
+{"question_id": "PPIL2-0062", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HSPA8 and PER2: no interaction detected\n- IL6R and CTSO: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HSPA8", "protein_2": "PER2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "IL6R", "protein_2": "CTSO", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [524651, 1887372], "include_positive": false}}
+{"question_id": "PPIL2-0063", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TSPYL2 and BOLA2: no interaction detected\n- APH1A and TFB2M: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSPYL2", "protein_2": "BOLA2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "APH1A", "protein_2": "TFB2M", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [486240, 1176978], "include_positive": true}}
+{"question_id": "PPIL2-0064", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CAMLG and STT3B: no interaction detected\n- NAA40 and MTRNR2L5: no interaction detected\n- ZNF415 and MARVELD2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CAMLG", "protein_2": "STT3B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NAA40", "protein_2": "MTRNR2L5", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ZNF415", "protein_2": "MARVELD2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [654415, 1895214, 285789], "include_positive": false}}
+{"question_id": "PPIL2-0065", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PRKCZ and SPCS3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PRKCZ", "protein_2": "SPCS3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1061168], "include_positive": false}}
+{"question_id": "PPIL2-0066", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PLOD3 and CFAP20: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PLOD3", "protein_2": "CFAP20", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [75737], "include_positive": false}}
+{"question_id": "PPIL2-0067", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CHMP7 and YEATS2: no interaction detected\n- TENM4 and ZNG1A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHMP7", "protein_2": "YEATS2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TENM4", "protein_2": "ZNG1A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [509774, 365630], "include_positive": true}}
+{"question_id": "PPIL2-0068", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SLC16A13 and COMMD9: no interaction detected\n- LIPF and DYNC2LI1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLC16A13", "protein_2": "COMMD9", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "LIPF", "protein_2": "DYNC2LI1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [387585, 135950], "include_positive": false}}
+{"question_id": "PPIL2-0069", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP8A1 and CWC15: no interaction detected\n- FGA and KCNJ5: no interaction detected\n- DLGAP1 and CLDND2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP8A1", "protein_2": "CWC15", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "FGA", "protein_2": "KCNJ5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DLGAP1", "protein_2": "CLDND2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [819216, 1634765, 34453], "include_positive": false}}
+{"question_id": "PPIL2-0070", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RNF34 and EFHB: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNF34", "protein_2": "EFHB", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2168241], "include_positive": false}}
+{"question_id": "PPIL2-0071", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- INTS3 and KCNJ3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "INTS3", "protein_2": "KCNJ3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1157135], "include_positive": true}}
+{"question_id": "PPIL2-0072", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RNF19B and DNAJB12: no interaction detected\n- PRKAG2 and COL11A2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNF19B", "protein_2": "DNAJB12", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PRKAG2", "protein_2": "COL11A2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2126168, 1466776], "include_positive": false}}
+{"question_id": "PPIL2-0073", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MAX and VPS18: no interaction detected\n- HBG1 and ATF6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MAX", "protein_2": "VPS18", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HBG1", "protein_2": "ATF6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [600571, 804779], "include_positive": false}}
+{"question_id": "PPIL2-0074", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CENPK and UQCR11: no interaction detected\n- ZBTB8B and RNF183: no interaction detected\n- KLF3 and HPGD: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CENPK", "protein_2": "UQCR11", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZBTB8B", "protein_2": "RNF183", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "KLF3", "protein_2": "HPGD", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1371683, 424582, 1911512], "include_positive": true}}
+{"question_id": "PPIL2-0075", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SLC9A6 and ZNF560: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLC9A6", "protein_2": "ZNF560", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2193882], "include_positive": false}}
+{"question_id": "PPIL2-0076", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GOLGA8T and USP42: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GOLGA8T", "protein_2": "USP42", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1776939], "include_positive": false}}
+{"question_id": "PPIL2-0077", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ABHD11 and TCP11: no interaction detected\n- TULP2 and CIPC: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ABHD11", "protein_2": "TCP11", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "TULP2", "protein_2": "CIPC", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [429727, 28922], "include_positive": false}}
+{"question_id": "PPIL2-0078", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ANKRD55 and FDXACB1: no interaction detected\n- SMARCE1 and MUS81: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ANKRD55", "protein_2": "FDXACB1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SMARCE1", "protein_2": "MUS81", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [332462, 1415936], "include_positive": false}}
+{"question_id": "PPIL2-0079", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- NDUFAB1 and GNE: no interaction detected\n- KYAT1 and SLC13A5: no interaction detected\n- LAMB1 and CTNNB1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NDUFAB1", "protein_2": "GNE", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "KYAT1", "protein_2": "SLC13A5", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "LAMB1", "protein_2": "CTNNB1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [36797, 326577, 1493568], "include_positive": false}}
+{"question_id": "PPIL2-0080", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MTX2 and TSEN2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MTX2", "protein_2": "TSEN2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [858300], "include_positive": false}}
+{"question_id": "PPIL2-0081", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SLITRK3 and OR7G3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLITRK3", "protein_2": "OR7G3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1850416], "include_positive": false}}
+{"question_id": "PPIL2-0082", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PGGT1B and ANKRA2: no interaction detected\n- HPS5 and CDRT15L2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PGGT1B", "protein_2": "ANKRA2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "HPS5", "protein_2": "CDRT15L2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [239695, 1761564], "include_positive": false}}
+{"question_id": "PPIL2-0083", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SLC10A2 and FAM124A: no interaction detected\n- DARS2 and CAMK2A: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLC10A2", "protein_2": "FAM124A", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "DARS2", "protein_2": "CAMK2A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [289743, 371742], "include_positive": false}}
+{"question_id": "PPIL2-0084", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TSEN54 and HTR3D: no interaction detected\n- XPOT and CD163L1: no interaction detected\n- TFPT and SOD2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSEN54", "protein_2": "HTR3D", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "XPOT", "protein_2": "CD163L1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "TFPT", "protein_2": "SOD2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [748046, 1814905, 1875687], "include_positive": false}}
+{"question_id": "PPIL2-0085", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PXT1 and CYP4V2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PXT1", "protein_2": "CYP4V2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2130749], "include_positive": true}}
+{"question_id": "PPIL2-0086", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CHRAC1 and F2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHRAC1", "protein_2": "F2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [697977], "include_positive": false}}
+{"question_id": "PPIL2-0087", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ZNF778 and TRNT1: no interaction detected\n- SNRPB and E2F2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZNF778", "protein_2": "TRNT1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SNRPB", "protein_2": "E2F2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2209407, 641558], "include_positive": false}}
+{"question_id": "PPIL2-0088", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- FNTB and LSM5: no interaction detected\n- PPP3R2 and SRPRA: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FNTB", "protein_2": "LSM5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PPP3R2", "protein_2": "SRPRA", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1483954, 1282153], "include_positive": true}}
+{"question_id": "PPIL2-0089", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TJAP1 and STRIP1: no interaction detected\n- MYPOP and CD200R1: no interaction detected\n- GPIHBP1 and ANAPC7: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TJAP1", "protein_2": "STRIP1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MYPOP", "protein_2": "CD200R1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "GPIHBP1", "protein_2": "ANAPC7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2088792, 396273, 1356787], "include_positive": true}}
+{"question_id": "PPIL2-0090", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NCAPH2 and KIF3B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NCAPH2", "protein_2": "KIF3B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1524171], "include_positive": false}}
+{"question_id": "PPIL2-0091", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- LIMK1 and ELMO1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LIMK1", "protein_2": "ELMO1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [239922], "include_positive": false}}
+{"question_id": "PPIL2-0092", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CDR2 and ZNF276: no interaction detected\n- SCNN1B and KIF3A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDR2", "protein_2": "ZNF276", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SCNN1B", "protein_2": "KIF3A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2022180, 710145], "include_positive": false}}
+{"question_id": "PPIL2-0093", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- AACS and TBL1XR1: no interaction detected\n- RBCK1 and BBS2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AACS", "protein_2": "TBL1XR1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "RBCK1", "protein_2": "BBS2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [396025, 798586], "include_positive": false}}
+{"question_id": "PPIL2-0094", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- AQP7 and CACNA2D3: no interaction detected\n- SMARCC1 and MEFV: no interaction detected\n- RAD51D and WDR45: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AQP7", "protein_2": "CACNA2D3", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SMARCC1", "protein_2": "MEFV", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RAD51D", "protein_2": "WDR45", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1791784, 957904, 1841804], "include_positive": true}}
+{"question_id": "PPIL2-0095", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KPNA5 and ITGA7: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KPNA5", "protein_2": "ITGA7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1139399], "include_positive": false}}
+{"question_id": "PPIL2-0096", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ARHGEF39 and MOCOS: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ARHGEF39", "protein_2": "MOCOS", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [417545], "include_positive": false}}
+{"question_id": "PPIL2-0097", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HAUS8 and ATP6V1C1: no interaction detected\n- KPNA4 and RABIF: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HAUS8", "protein_2": "ATP6V1C1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KPNA4", "protein_2": "RABIF", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [940504, 33399], "include_positive": false}}
+{"question_id": "PPIL2-0098", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- GET3 and CDK12: no interaction detected\n- CHMP1B and CARD17P: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GET3", "protein_2": "CDK12", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CHMP1B", "protein_2": "CARD17P", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [967906, 2103870], "include_positive": true}}
+{"question_id": "PPIL2-0099", "task": "ppi-l2", "split": "val", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ORC1 and ATF6B: no interaction detected\n- SUV39H1 and STAT5A: no interaction detected\n- KHDC3L and NR1I2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ORC1", "protein_2": "ATF6B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SUV39H1", "protein_2": "STAT5A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KHDC3L", "protein_2": "NR1I2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [529310, 734091, 633068], "include_positive": false}}
+{"question_id": "PPIL2-0100", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- OR1J4 and ECHDC3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "OR1J4", "protein_2": "ECHDC3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2179392], "include_positive": true}}
+{"question_id": "PPIL2-0101", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CCT7 and MIS18A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CCT7", "protein_2": "MIS18A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1325466], "include_positive": false}}
+{"question_id": "PPIL2-0102", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- YBX1 and NFRKB: no interaction detected\n- MYL12B and RPL6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "YBX1", "protein_2": "NFRKB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MYL12B", "protein_2": "RPL6", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [669558, 1798667], "include_positive": false}}
+{"question_id": "PPIL2-0103", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ZNF835 and SDK1: no interaction detected\n- RNF31 and ZC3H3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZNF835", "protein_2": "SDK1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RNF31", "protein_2": "ZC3H3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2138675, 964994], "include_positive": false}}
+{"question_id": "PPIL2-0104", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CCNE1 and IFT25: no interaction detected\n- EXOC5 and GABRA6: no interaction detected\n- SDHD and TERF2IP: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CCNE1", "protein_2": "IFT25", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "EXOC5", "protein_2": "GABRA6", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SDHD", "protein_2": "TERF2IP", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [187358, 644635, 570720], "include_positive": true}}
+{"question_id": "PPIL2-0105", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- VIRMA and SPCS2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VIRMA", "protein_2": "SPCS2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1024590], "include_positive": false}}
+{"question_id": "PPIL2-0106", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RBM5 and COX7B2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM5", "protein_2": "COX7B2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1992197], "include_positive": false}}
+{"question_id": "PPIL2-0107", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CPSF4 and TAF5L: no interaction detected\n- TFDP1 and CSF2RA: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CPSF4", "protein_2": "TAF5L", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TFDP1", "protein_2": "CSF2RA", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1298849, 684771], "include_positive": false}}
+{"question_id": "PPIL2-0108", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MICOS10 and EIF3K: no interaction detected\n- RER1 and BYSL: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MICOS10", "protein_2": "EIF3K", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RER1", "protein_2": "BYSL", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1216017, 50547], "include_positive": false}}
+{"question_id": "PPIL2-0109", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- EIF4E2 and CTH: no interaction detected\n- SKA3 and TRAC: no interaction detected\n- PDE5A and FKBP1A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EIF4E2", "protein_2": "CTH", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SKA3", "protein_2": "TRAC", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PDE5A", "protein_2": "FKBP1A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1825554, 823281, 97791], "include_positive": false}}
+{"question_id": "PPIL2-0110", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CDK5RAP3 and SH3BGR: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDK5RAP3", "protein_2": "SH3BGR", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1999052], "include_positive": false}}
+{"question_id": "PPIL2-0111", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CLDN2 and DPPA3: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLDN2", "protein_2": "DPPA3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [250156], "include_positive": false}}
+{"question_id": "PPIL2-0112", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- MID1IP1 and ABCA13: no interaction detected\n- CPSF1 and TLR1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MID1IP1", "protein_2": "ABCA13", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CPSF1", "protein_2": "TLR1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2143720, 1352593], "include_positive": false}}
+{"question_id": "PPIL2-0113", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- AFG1L and DIRAS2: no interaction detected\n- MCM4 and CUL4A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AFG1L", "protein_2": "DIRAS2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "MCM4", "protein_2": "CUL4A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [440112, 1227001], "include_positive": true}}
+{"question_id": "PPIL2-0114", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- KHK and TIGD7: no interaction detected\n- CDH24 and PAQR4: no interaction detected\n- PRMT6 and CLK4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KHK", "protein_2": "TIGD7", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CDH24", "protein_2": "PAQR4", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PRMT6", "protein_2": "CLK4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [230327, 2143572, 464315], "include_positive": false}}
+{"question_id": "PPIL2-0115", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- APLNR and IST1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "APLNR", "protein_2": "IST1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1961064], "include_positive": false}}
+{"question_id": "PPIL2-0116", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PRKRA and C8A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PRKRA", "protein_2": "C8A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1158628], "include_positive": true}}
+{"question_id": "PPIL2-0117", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TSN and DNMT3L: no interaction detected\n- HRAS and KRTAP21-2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSN", "protein_2": "DNMT3L", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HRAS", "protein_2": "KRTAP21-2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [654027, 120735], "include_positive": false}}
+{"question_id": "PPIL2-0118", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- EIPR1 and NXT2: no interaction detected\n- MIS12 and CPSF2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EIPR1", "protein_2": "NXT2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "MIS12", "protein_2": "CPSF2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [340600, 1263924], "include_positive": false}}
+{"question_id": "PPIL2-0119", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RCOR3 and RMP24: no interaction detected\n- HRG and GABARAPL1: no interaction detected\n- SMARCB1 and CDK5R1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RCOR3", "protein_2": "RMP24", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "HRG", "protein_2": "GABARAPL1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SMARCB1", "protein_2": "CDK5R1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2074159, 128507, 873097], "include_positive": false}}
+{"question_id": "PPIL2-0120", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RBM42 and IDH3A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM42", "protein_2": "IDH3A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1525039], "include_positive": false}}
+{"question_id": "PPIL2-0121", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DBP and CRB2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DBP", "protein_2": "CRB2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1575630], "include_positive": true}}
+{"question_id": "PPIL2-0122", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- P2RX6 and PIF1: no interaction detected\n- RFC5 and ATP6V0E2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "P2RX6", "protein_2": "PIF1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RFC5", "protein_2": "ATP6V0E2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1808406, 827778], "include_positive": false}}
+{"question_id": "PPIL2-0123", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- EXOC3L2 and SYTL1: no interaction detected\n- PALB2 and SIN3A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EXOC3L2", "protein_2": "SYTL1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PALB2", "protein_2": "SIN3A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [329698, 1091663], "include_positive": true}}
+{"question_id": "PPIL2-0124", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATG5 and UXT: no interaction detected\n- RPN1 and PFDN2: no interaction detected\n- NLRP5 and THOC5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATG5", "protein_2": "UXT", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RPN1", "protein_2": "PFDN2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NLRP5", "protein_2": "THOC5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1258649, 1566021, 786781], "include_positive": false}}
+{"question_id": "PPIL2-0125", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- IARS1 and NFATC4: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IARS1", "protein_2": "NFATC4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1969138], "include_positive": true}}
+{"question_id": "PPIL2-0126", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CASP8 and TMEM258: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CASP8", "protein_2": "TMEM258", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1270235], "include_positive": true}}
+{"question_id": "PPIL2-0127", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- FRYL and PRR4: no interaction detected\n- CREB3 and ATP8B3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FRYL", "protein_2": "PRR4", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CREB3", "protein_2": "ATP8B3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1850052, 1534287], "include_positive": false}}
+{"question_id": "PPIL2-0128", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- DTNBP1 and PDCD6: no interaction detected\n- H3C1 and EMC1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DTNBP1", "protein_2": "PDCD6", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "H3C1", "protein_2": "EMC1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [84923, 1663055], "include_positive": false}}
+{"question_id": "PPIL2-0129", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KPNB1 and ITGA11: no interaction detected\n- ZNF20 and USP20: no interaction detected\n- LBX1 and TAF13: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KPNB1", "protein_2": "ITGA11", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZNF20", "protein_2": "USP20", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "LBX1", "protein_2": "TAF13", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1536627, 170438, 239019], "include_positive": false}}
+{"question_id": "PPIL2-0130", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PRPH and CAPZA3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PRPH", "protein_2": "CAPZA3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1968475], "include_positive": false}}
+{"question_id": "PPIL2-0131", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COG5 and TAF7: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COG5", "protein_2": "TAF7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1517630], "include_positive": true}}
+{"question_id": "PPIL2-0132", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- KRTAP19-3 and FUBP3: no interaction detected\n- SVOPL and ZNF234: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KRTAP19-3", "protein_2": "FUBP3", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SVOPL", "protein_2": "ZNF234", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2137964, 2052486], "include_positive": true}}
+{"question_id": "PPIL2-0133", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HGS and ATG101: no interaction detected\n- ZNF35 and RORC: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HGS", "protein_2": "ATG101", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZNF35", "protein_2": "RORC", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1210413, 160960], "include_positive": false}}
+{"question_id": "PPIL2-0134", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMARCA2 and H3C1: no interaction detected\n- RAD51 and CHRNA9: no interaction detected\n- POLD1 and POT1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMARCA2", "protein_2": "H3C1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RAD51", "protein_2": "CHRNA9", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "POLD1", "protein_2": "POT1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1499372, 518215, 730690], "include_positive": true}}
+{"question_id": "PPIL2-0135", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- NUP133 and L7N2F9: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NUP133", "protein_2": "L7N2F9", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1781198], "include_positive": false}}
+{"question_id": "PPIL2-0136", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CLCN7 and OBSL1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLCN7", "protein_2": "OBSL1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [951110], "include_positive": false}}
+{"question_id": "PPIL2-0137", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COX5A and USP39: no interaction detected\n- TUBA8 and CHMP3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COX5A", "protein_2": "USP39", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TUBA8", "protein_2": "CHMP3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1521461, 495901], "include_positive": false}}
+{"question_id": "PPIL2-0138", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CPSF6 and SNUPN: no interaction detected\n- SELL and HENMT1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CPSF6", "protein_2": "SNUPN", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SELL", "protein_2": "HENMT1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1466308, 162248], "include_positive": false}}
+{"question_id": "PPIL2-0139", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- LAPTM5 and RAB30: no interaction detected\n- PSEN2 and RBPJ: no interaction detected\n- ICE2 and TRGC2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LAPTM5", "protein_2": "RAB30", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PSEN2", "protein_2": "RBPJ", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ICE2", "protein_2": "TRGC2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [299315, 1554490, 985213], "include_positive": false}}
+{"question_id": "PPIL2-0140", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ERLIN1 and SMARCA1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ERLIN1", "protein_2": "SMARCA1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [687899], "include_positive": false}}
+{"question_id": "PPIL2-0141", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SPTSSA and HTATSF1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SPTSSA", "protein_2": "HTATSF1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1085012], "include_positive": true}}
+{"question_id": "PPIL2-0142", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BCL2L11 and EMC3: no interaction detected\n- TMEM242 and PSD3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BCL2L11", "protein_2": "EMC3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TMEM242", "protein_2": "PSD3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1651059, 2234489], "include_positive": true}}
+{"question_id": "PPIL2-0143", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP6V1G2 and BAZ1A: no interaction detected\n- HAUS3 and HSP90AA1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP6V1G2", "protein_2": "BAZ1A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HAUS3", "protein_2": "HSP90AA1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1037536, 947016], "include_positive": false}}
+{"question_id": "PPIL2-0144", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ERLIN1 and EXOC4: no interaction detected\n- TRAF3IP1 and TOE1: no interaction detected\n- CFAP206 and NPVF: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ERLIN1", "protein_2": "EXOC4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRAF3IP1", "protein_2": "TOE1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CFAP206", "protein_2": "NPVF", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [826456, 2185774, 2157375], "include_positive": false}}
+{"question_id": "PPIL2-0145", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CHMP1B and GABRA2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHMP1B", "protein_2": "GABRA2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [819090], "include_positive": false}}
+{"question_id": "PPIL2-0146", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ASCC1 and MPC1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ASCC1", "protein_2": "MPC1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [874982], "include_positive": false}}
+{"question_id": "PPIL2-0147", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TSN and BBS5: no interaction detected\n- PAEP and TFPI2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSN", "protein_2": "BBS5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PAEP", "protein_2": "TFPI2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [887520, 1889078], "include_positive": true}}
+{"question_id": "PPIL2-0148", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- VGLL2 and KDM4E: no interaction detected\n- SAP30L and JADE2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VGLL2", "protein_2": "KDM4E", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SAP30L", "protein_2": "JADE2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1763713, 886620], "include_positive": false}}
+{"question_id": "PPIL2-0149", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- WWP2 and NSG1: no interaction detected\n- PDCD6 and PAAT: no interaction detected\n- CCNK and UBL4A: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "WWP2", "protein_2": "NSG1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PDCD6", "protein_2": "PAAT", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CCNK", "protein_2": "UBL4A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [29281, 84944, 707965], "include_positive": false}}
+{"question_id": "PPIL2-0150", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PTP4A2 and DHRS2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PTP4A2", "protein_2": "DHRS2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [290371], "include_positive": true}}
+{"question_id": "PPIL2-0151", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NFYB and BARD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NFYB", "protein_2": "BARD1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [641749], "include_positive": false}}
+{"question_id": "PPIL2-0152", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- F10 and SF3B1: no interaction detected\n- VPS4A and IBA57: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "F10", "protein_2": "SF3B1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "VPS4A", "protein_2": "IBA57", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [501504, 1597020], "include_positive": true}}
+{"question_id": "PPIL2-0153", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP6V1G1 and SPTLC1: no interaction detected\n- ZMYND12 and DCBLD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP6V1G1", "protein_2": "SPTLC1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZMYND12", "protein_2": "DCBLD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [783241, 2169546], "include_positive": false}}
+{"question_id": "PPIL2-0154", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TOX and SSR3: no interaction detected\n- JUNB and CDKL3: no interaction detected\n- RELA and F5: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TOX", "protein_2": "SSR3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "JUNB", "protein_2": "CDKL3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "RELA", "protein_2": "F5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [100523, 171793, 1083517], "include_positive": false}}
+{"question_id": "PPIL2-0155", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GJA1 and SNRNP25: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GJA1", "protein_2": "SNRNP25", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1916325], "include_positive": false}}
+{"question_id": "PPIL2-0156", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RARS1 and ITGA10: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RARS1", "protein_2": "ITGA10", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1465259], "include_positive": false}}
+{"question_id": "PPIL2-0157", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PHF20 and TFPI2: no interaction detected\n- NCAPG and GUCY1A1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PHF20", "protein_2": "TFPI2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "NCAPG", "protein_2": "GUCY1A1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1978442, 1429667], "include_positive": false}}
+{"question_id": "PPIL2-0158", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP6V0E1 and RRP8: no interaction detected\n- SNRNP200 and SPTLC2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP6V0E1", "protein_2": "RRP8", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SNRNP200", "protein_2": "SPTLC2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1086828, 1685521], "include_positive": false}}
+{"question_id": "PPIL2-0159", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NR1I2 and INTU: no interaction detected\n- ZDHHC17 and GFM2: no interaction detected\n- ENPP7 and GRIA2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NR1I2", "protein_2": "INTU", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZDHHC17", "protein_2": "GFM2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "ENPP7", "protein_2": "GRIA2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [757468, 402581, 1970163], "include_positive": false}}
+{"question_id": "PPIL2-0160", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CFAP96 and POU3F1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CFAP96", "protein_2": "POU3F1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1757456], "include_positive": false}}
+{"question_id": "PPIL2-0161", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CASP9 and FIP1L1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CASP9", "protein_2": "FIP1L1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1534712], "include_positive": false}}
+{"question_id": "PPIL2-0162", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- GRIN1 and ITFG2: no interaction detected\n- VPS16 and GANAB: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GRIN1", "protein_2": "ITFG2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "VPS16", "protein_2": "GANAB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [519426, 979150], "include_positive": true}}
+{"question_id": "PPIL2-0163", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RBM18 and EPHA1: no interaction detected\n- RHEBL1 and SPRYD4: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM18", "protein_2": "EPHA1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RHEBL1", "protein_2": "SPRYD4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1925834, 431974], "include_positive": false}}
+{"question_id": "PPIL2-0164", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BLOC1S4 and PIK3CB: no interaction detected\n- ABCC9 and YTHDF1: no interaction detected\n- NFKB1 and NFE2L1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BLOC1S4", "protein_2": "PIK3CB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ABCC9", "protein_2": "YTHDF1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "NFKB1", "protein_2": "NFE2L1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [841036, 1827071, 526876], "include_positive": true}}
+{"question_id": "PPIL2-0165", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- FGFBP3 and THSD1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FGFBP3", "protein_2": "THSD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2182220], "include_positive": true}}
+{"question_id": "PPIL2-0166", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RBM4B and LINC03042: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM4B", "protein_2": "LINC03042", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2129481], "include_positive": false}}
+{"question_id": "PPIL2-0167", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP6V0D1 and NELFB: no interaction detected\n- MCM7 and UBL4A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP6V0D1", "protein_2": "NELFB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MCM7", "protein_2": "UBL4A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [612890, 1019555], "include_positive": false}}
+{"question_id": "PPIL2-0168", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- POLE4 and PRPF4: no interaction detected\n- RBBP5 and YEATS2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "POLE4", "protein_2": "PRPF4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RBBP5", "protein_2": "YEATS2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1420812, 694864], "include_positive": true}}
+{"question_id": "PPIL2-0169", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BOLA3 and IGHD: no interaction detected\n- E2F2 and MED26: no interaction detected\n- ESAM and PLK3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BOLA3", "protein_2": "IGHD", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "E2F2", "protein_2": "MED26", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ESAM", "protein_2": "PLK3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1516694, 741374, 452068], "include_positive": false}}
+{"question_id": "PPIL2-0170", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KLRC3 and COL5A2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KLRC3", "protein_2": "COL5A2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [608482], "include_positive": false}}
+{"question_id": "PPIL2-0171", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CASP1 and ATP8B4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CASP1", "protein_2": "ATP8B4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1636879], "include_positive": false}}
+{"question_id": "PPIL2-0172", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NELFCD and HBG1: no interaction detected\n- SNU13 and CPSF3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NELFCD", "protein_2": "HBG1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SNU13", "protein_2": "CPSF3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1126960, 1150555], "include_positive": true}}
+{"question_id": "PPIL2-0173", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COG6 and IGLC7: no interaction detected\n- POLD1 and ACTR5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COG6", "protein_2": "IGLC7", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "POLD1", "protein_2": "ACTR5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1347304, 775034], "include_positive": false}}
+{"question_id": "PPIL2-0174", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CACNB1 and EXOSC9: no interaction detected\n- DPY30 and STRAP: no interaction detected\n- ECSIT and ITGA11: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CACNB1", "protein_2": "EXOSC9", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DPY30", "protein_2": "STRAP", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ECSIT", "protein_2": "ITGA11", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1183535, 1542325, 1602514], "include_positive": false}}
+{"question_id": "PPIL2-0175", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CLDN20 and EML5: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLDN20", "protein_2": "EML5", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2000871], "include_positive": false}}
+{"question_id": "PPIL2-0176", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- U2SURP and ADCY2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "U2SURP", "protein_2": "ADCY2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1800194], "include_positive": true}}
+{"question_id": "PPIL2-0177", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NAA10 and CENPM: no interaction detected\n- NSMCE2 and SDC1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NAA10", "protein_2": "CENPM", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NSMCE2", "protein_2": "SDC1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1266521, 785327], "include_positive": true}}
+{"question_id": "PPIL2-0178", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KCNJ11 and KNTC1: no interaction detected\n- COG2 and PFDN5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KCNJ11", "protein_2": "KNTC1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "COG2", "protein_2": "PFDN5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [946238, 1232830], "include_positive": false}}
+{"question_id": "PPIL2-0179", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BBS2 and DDB1: no interaction detected\n- CDX4 and SLC39A3: no interaction detected\n- HIGD2A and AIRE: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BBS2", "protein_2": "DDB1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CDX4", "protein_2": "SLC39A3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "HIGD2A", "protein_2": "AIRE", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [830665, 37739, 1819743], "include_positive": false}}
+{"question_id": "PPIL2-0180", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CYBA and GABRG2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CYBA", "protein_2": "GABRG2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1097551], "include_positive": true}}
+{"question_id": "PPIL2-0181", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KAT7 and FOXO3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KAT7", "protein_2": "FOXO3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [969418], "include_positive": true}}
+{"question_id": "PPIL2-0182", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ZNF177 and AKAP8L: no interaction detected\n- SH3D19 and DRICH1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZNF177", "protein_2": "AKAP8L", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SH3D19", "protein_2": "DRICH1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [295948, 344295], "include_positive": false}}
+{"question_id": "PPIL2-0183", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CHMP2A and BCL2: no interaction detected\n- EGR2 and DCAF8: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHMP2A", "protein_2": "BCL2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "EGR2", "protein_2": "DCAF8", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [673170, 155389], "include_positive": true}}
+{"question_id": "PPIL2-0184", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- C6orf89 and FBXL18: no interaction detected\n- SNX18 and HAPLN2: no interaction detected\n- GFER and PFKFB4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "C6orf89", "protein_2": "FBXL18", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SNX18", "protein_2": "HAPLN2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "GFER", "protein_2": "PFKFB4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [375944, 469750, 245852], "include_positive": false}}
+{"question_id": "PPIL2-0185", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TFPT and KPTN: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TFPT", "protein_2": "KPTN", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [566095], "include_positive": true}}
+{"question_id": "PPIL2-0186", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TOM1 and SELENOM: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TOM1", "protein_2": "SELENOM", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1827901], "include_positive": true}}
+{"question_id": "PPIL2-0187", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- EXOC6 and ERLIN2: no interaction detected\n- ZW10 and CTSB: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EXOC6", "protein_2": "ERLIN2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZW10", "protein_2": "CTSB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [675020, 1197510], "include_positive": false}}
+{"question_id": "PPIL2-0188", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BCL2L1 and CHMP3: no interaction detected\n- CDH24 and KAZALD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BCL2L1", "protein_2": "CHMP3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CDH24", "protein_2": "KAZALD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [749723, 2143581], "include_positive": false}}
+{"question_id": "PPIL2-0189", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PIK3CB and BBS7: no interaction detected\n- AKAP17A and ASPH: no interaction detected\n- FNDC8 and SETD4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PIK3CB", "protein_2": "BBS7", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "AKAP17A", "protein_2": "ASPH", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "FNDC8", "protein_2": "SETD4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1062332, 275469, 434651], "include_positive": false}}
+{"question_id": "PPIL2-0190", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDK13 and KATNAL2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDK13", "protein_2": "KATNAL2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1408504], "include_positive": false}}
+{"question_id": "PPIL2-0191", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- IFT74 and SGCE: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IFT74", "protein_2": "SGCE", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1619989], "include_positive": false}}
+{"question_id": "PPIL2-0192", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- C5 and STAG3: no interaction detected\n- ATP6V1H and TTN: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "C5", "protein_2": "STAG3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ATP6V1H", "protein_2": "TTN", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1512157, 577054], "include_positive": false}}
+{"question_id": "PPIL2-0193", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- C1QA and MCM9: no interaction detected\n- CGB3 and ATP6V1F: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "C1QA", "protein_2": "MCM9", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CGB3", "protein_2": "ATP6V1F", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [854712, 732378], "include_positive": true}}
+{"question_id": "PPIL2-0194", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TMEM30A and IFT122: no interaction detected\n- GPR119 and IGDCC3: no interaction detected\n- ITGAL and GLRX3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TMEM30A", "protein_2": "IFT122", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "GPR119", "protein_2": "IGDCC3", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ITGAL", "protein_2": "GLRX3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [701233, 2152667, 1059495], "include_positive": false}}
+{"question_id": "PPIL2-0195", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ECH1 and LDLRAP1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ECH1", "protein_2": "LDLRAP1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [290808], "include_positive": false}}
+{"question_id": "PPIL2-0196", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TMEM151A and SEMA3D: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TMEM151A", "protein_2": "SEMA3D", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1851516], "include_positive": false}}
+{"question_id": "PPIL2-0197", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SNRPD3 and PARD6G: no interaction detected\n- PIGS and ATP8B1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SNRPD3", "protein_2": "PARD6G", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PIGS", "protein_2": "ATP8B1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1584719, 1343150], "include_positive": true}}
+{"question_id": "PPIL2-0198", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HAUS8 and SAP30L: no interaction detected\n- TFPT and LUZP4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HAUS8", "protein_2": "SAP30L", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TFPT", "protein_2": "LUZP4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [851114, 795515], "include_positive": false}}
+{"question_id": "PPIL2-0199", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ABCC1 and AHCYL2: no interaction detected\n- ITGA6 and CACNA1C: no interaction detected\n- SYCE1L and ALOX12: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ABCC1", "protein_2": "AHCYL2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ITGA6", "protein_2": "CACNA1C", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SYCE1L", "protein_2": "ALOX12", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1947874, 543874, 1759038], "include_positive": false}}
+{"question_id": "PPIL2-0200", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CLDN4 and PRPF38A: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLDN4", "protein_2": "PRPF38A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [34677], "include_positive": false}}
+{"question_id": "PPIL2-0201", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MASP2 and PKD1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MASP2", "protein_2": "PKD1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1249754], "include_positive": true}}
+{"question_id": "PPIL2-0202", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TRAPPC13 and PER1: no interaction detected\n- NFIL3 and MTREX: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRAPPC13", "protein_2": "PER1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NFIL3", "protein_2": "MTREX", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1095945, 985092], "include_positive": true}}
+{"question_id": "PPIL2-0203", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PRR5L and C22orf23: no interaction detected\n- ZNHIT2 and EXOC7: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PRR5L", "protein_2": "C22orf23", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "ZNHIT2", "protein_2": "EXOC7", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [365567, 498570], "include_positive": false}}
+{"question_id": "PPIL2-0204", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MED15 and IL12B: no interaction detected\n- MX2 and NR3C1: no interaction detected\n- MOB2 and SLC7A8: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MED15", "protein_2": "IL12B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MX2", "protein_2": "NR3C1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MOB2", "protein_2": "SLC7A8", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [886303, 1875590, 383648], "include_positive": true}}
+{"question_id": "PPIL2-0205", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PCCA and FANCL: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PCCA", "protein_2": "FANCL", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1085108], "include_positive": false}}
+{"question_id": "PPIL2-0206", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- RBM3 and GJB4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM3", "protein_2": "GJB4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [271880], "include_positive": false}}
+{"question_id": "PPIL2-0207", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- POLE and TRAF3IP1: no interaction detected\n- MAD2L1 and NXT1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "POLE", "protein_2": "TRAF3IP1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MAD2L1", "protein_2": "NXT1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1652007, 678993], "include_positive": true}}
+{"question_id": "PPIL2-0208", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- VPS52 and SNTG1: no interaction detected\n- STAT6 and NUF2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VPS52", "protein_2": "SNTG1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "STAT6", "protein_2": "NUF2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1289103, 1388350], "include_positive": false}}
+{"question_id": "PPIL2-0209", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TMEM141 and TAS2R39: no interaction detected\n- TLR4 and IFT70B: no interaction detected\n- TAS2R39 and TIA1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TMEM141", "protein_2": "TAS2R39", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "TLR4", "protein_2": "IFT70B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TAS2R39", "protein_2": "TIA1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2004008, 1205740, 1945111], "include_positive": false}}
+{"question_id": "PPIL2-0210", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RNASEK and HAUS1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNASEK", "protein_2": "HAUS1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [534799], "include_positive": false}}
+{"question_id": "PPIL2-0211", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CTAG2 and BRD7: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CTAG2", "protein_2": "BRD7", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [91079], "include_positive": true}}
+{"question_id": "PPIL2-0212", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HBG2 and SMC5: no interaction detected\n- CHMP2A and LAMA2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HBG2", "protein_2": "SMC5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CHMP2A", "protein_2": "LAMA2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [638082, 1044310], "include_positive": true}}
+{"question_id": "PPIL2-0213", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ACSL3 and SPACA4: no interaction detected\n- GLI1 and UIMC1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ACSL3", "protein_2": "SPACA4", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "GLI1", "protein_2": "UIMC1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1859499, 1100606], "include_positive": false}}
+{"question_id": "PPIL2-0214", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PCYOX1 and EXOC3L4: no interaction detected\n- NDUFB6 and MAF1: no interaction detected\n- TADA3 and PKLR: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PCYOX1", "protein_2": "EXOC3L4", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "NDUFB6", "protein_2": "MAF1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "TADA3", "protein_2": "PKLR", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2069208, 103055, 89009], "include_positive": true}}
+{"question_id": "PPIL2-0215", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RBM42 and COQ4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM42", "protein_2": "COQ4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1667803], "include_positive": false}}
+{"question_id": "PPIL2-0216", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SF1 and MED28: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SF1", "protein_2": "MED28", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [676888], "include_positive": true}}
+{"question_id": "PPIL2-0217", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- BEND6 and ZNF112: no interaction detected\n- VN1R1 and GPR179: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BEND6", "protein_2": "ZNF112", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "VN1R1", "protein_2": "GPR179", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2092881, 2118530], "include_positive": false}}
+{"question_id": "PPIL2-0218", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PRKAG3 and TIMM29: no interaction detected\n- PARD6G and NUBP1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PRKAG3", "protein_2": "TIMM29", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PARD6G", "protein_2": "NUBP1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1186832, 1667389], "include_positive": false}}
+{"question_id": "PPIL2-0219", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PTAR1 and OPHN1: no interaction detected\n- GTF2F1 and MED13: no interaction detected\n- CYB5R1 and ZNF346: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PTAR1", "protein_2": "OPHN1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "GTF2F1", "protein_2": "MED13", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CYB5R1", "protein_2": "ZNF346", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1829157, 548137, 498542], "include_positive": false}}
+{"question_id": "PPIL2-0220", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- GINS4 and JUND: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GINS4", "protein_2": "JUND", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [545467], "include_positive": true}}
+{"question_id": "PPIL2-0221", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SAP18 and DTWD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SAP18", "protein_2": "DTWD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1787009], "include_positive": false}}
+{"question_id": "PPIL2-0222", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMAD4 and CRY1: no interaction detected\n- AP1B1 and COQ6: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMAD4", "protein_2": "CRY1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "AP1B1", "protein_2": "COQ6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1152048, 1366779], "include_positive": true}}
+{"question_id": "PPIL2-0223", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PCSK9 and NCAPH: no interaction detected\n- RAMP1 and TMEM186: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PCSK9", "protein_2": "NCAPH", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RAMP1", "protein_2": "TMEM186", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1570615, 1421047], "include_positive": false}}
+{"question_id": "PPIL2-0224", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TFG and CLDN16: no interaction detected\n- RAF1 and C12orf50: no interaction detected\n- SEC23A and FAIM2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TFG", "protein_2": "CLDN16", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RAF1", "protein_2": "C12orf50", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SEC23A", "protein_2": "FAIM2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2194651, 127456, 2060370], "include_positive": true}}
+{"question_id": "PPIL2-0225", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ASAP2 and CHCHD2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ASAP2", "protein_2": "CHCHD2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1808845], "include_positive": false}}
+{"question_id": "PPIL2-0226", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TMA16 and ATP5PD: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TMA16", "protein_2": "ATP5PD", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1844744], "include_positive": false}}
+{"question_id": "PPIL2-0227", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- FOSL2 and BAG6: no interaction detected\n- HBA1 and TIMM50: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FOSL2", "protein_2": "BAG6", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HBA1", "protein_2": "TIMM50", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [819377, 1723492], "include_positive": true}}
+{"question_id": "PPIL2-0228", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- HOXB1 and DHRS4L2: no interaction detected\n- LAP3 and HSPB9: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HOXB1", "protein_2": "DHRS4L2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "LAP3", "protein_2": "HSPB9", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1909435, 1939215], "include_positive": false}}
+{"question_id": "PPIL2-0229", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- FNTB and BBC3: no interaction detected\n- DDX21 and AP3M1: no interaction detected\n- GRPEL1 and CHTOP: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FNTB", "protein_2": "BBC3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DDX21", "protein_2": "AP3M1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "GRPEL1", "protein_2": "CHTOP", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1655528, 1158719, 489974], "include_positive": true}}
+{"question_id": "PPIL2-0230", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT5A and PIGX: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT5A", "protein_2": "PIGX", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1717373], "include_positive": false}}
+{"question_id": "PPIL2-0231", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- MFSD6 and TM4SF1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MFSD6", "protein_2": "TM4SF1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1942539], "include_positive": false}}
+{"question_id": "PPIL2-0232", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CRYBA2 and RNASE11: no interaction detected\n- EXOC6 and F5: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CRYBA2", "protein_2": "RNASE11", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "EXOC6", "protein_2": "F5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [239982, 885457], "include_positive": false}}
+{"question_id": "PPIL2-0233", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CASP9 and EXTL1: no interaction detected\n- PIK3R6 and CEBPD: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CASP9", "protein_2": "EXTL1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PIK3R6", "protein_2": "CEBPD", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [244893, 1447051], "include_positive": false}}
+{"question_id": "PPIL2-0234", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ITGAM and DAD1: no interaction detected\n- DLG3 and CXXC1: no interaction detected\n- LRRC4C and CFDP1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ITGAM", "protein_2": "DAD1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DLG3", "protein_2": "CXXC1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "LRRC4C", "protein_2": "CFDP1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [899961, 1381118, 490723], "include_positive": true}}
+{"question_id": "PPIL2-0235", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- FLNA and RIDA: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FLNA", "protein_2": "RIDA", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [179889], "include_positive": false}}
+{"question_id": "PPIL2-0236", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- UQCRB and TAF4B: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "UQCRB", "protein_2": "TAF4B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1141307], "include_positive": true}}
+{"question_id": "PPIL2-0237", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NAA16 and MRPS35: no interaction detected\n- EIF4A2 and SF3B6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NAA16", "protein_2": "MRPS35", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "EIF4A2", "protein_2": "SF3B6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1554821, 790155], "include_positive": false}}
+{"question_id": "PPIL2-0238", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TEAD1 and SNU13: no interaction detected\n- ATXN7 and IKBKB: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TEAD1", "protein_2": "SNU13", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ATXN7", "protein_2": "IKBKB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1586918, 1696505], "include_positive": false}}
+{"question_id": "PPIL2-0239", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PABPC1 and CASTOR2: no interaction detected\n- BCL2L11 and UBE2N: no interaction detected\n- SPATA18 and ASB3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PABPC1", "protein_2": "CASTOR2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "BCL2L11", "protein_2": "UBE2N", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SPATA18", "protein_2": "ASB3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1703931, 1453163, 434468], "include_positive": false}}
+{"question_id": "PPIL2-0240", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- POLE2 and AP3M1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "POLE2", "protein_2": "AP3M1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1211973], "include_positive": true}}
+{"question_id": "PPIL2-0241", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PPY and LEG1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PPY", "protein_2": "LEG1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1870215], "include_positive": false}}
+{"question_id": "PPIL2-0242", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CCND1 and RAD23B: no interaction detected\n- HOOK2 and GCK: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CCND1", "protein_2": "RAD23B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HOOK2", "protein_2": "GCK", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [736482, 207651], "include_positive": false}}
+{"question_id": "PPIL2-0243", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PADI1 and AIRE: no interaction detected\n- ITGB1 and MRPS31: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PADI1", "protein_2": "AIRE", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ITGB1", "protein_2": "MRPS31", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1819753, 1203604], "include_positive": false}}
+{"question_id": "PPIL2-0244", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- NUCB2 and H3-4: no interaction detected\n- CDK6 and C6: no interaction detected\n- USF1 and CCT8: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NUCB2", "protein_2": "H3-4", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CDK6", "protein_2": "C6", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "USF1", "protein_2": "CCT8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [268505, 902332, 1530605], "include_positive": true}}
+{"question_id": "PPIL2-0245", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RFTN2 and ZIC2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RFTN2", "protein_2": "ZIC2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1857321], "include_positive": true}}
+{"question_id": "PPIL2-0246", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NAA15 and VPS28: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NAA15", "protein_2": "VPS28", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1261175], "include_positive": true}}
+{"question_id": "PPIL2-0247", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TCF4 and CEACAM8: no interaction detected\n- VWC2 and ZDHHC7: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TCF4", "protein_2": "CEACAM8", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "VWC2", "protein_2": "ZDHHC7", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1912450, 330689], "include_positive": false}}
+{"question_id": "PPIL2-0248", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- BEX1 and COMMD10: no interaction detected\n- NPRL3 and VPS72: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BEX1", "protein_2": "COMMD10", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "NPRL3", "protein_2": "VPS72", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [490208, 544715], "include_positive": true}}
+{"question_id": "PPIL2-0249", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RBM26 and IGHG1: no interaction detected\n- DESI2 and NDUFB9: no interaction detected\n- PCYT1A and S1PR3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM26", "protein_2": "IGHG1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DESI2", "protein_2": "NDUFB9", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PCYT1A", "protein_2": "S1PR3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1063496, 476931, 226912], "include_positive": false}}
+{"question_id": "PPIL2-0250", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DKC1 and YEATS2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DKC1", "protein_2": "YEATS2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [613925], "include_positive": true}}
+{"question_id": "PPIL2-0251", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- UBE2D1 and STMN3: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "UBE2D1", "protein_2": "STMN3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [234564], "include_positive": false}}
+{"question_id": "PPIL2-0252", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RABIF and TNFRSF13C: no interaction detected\n- COL8A2 and IGHG2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RABIF", "protein_2": "TNFRSF13C", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "COL8A2", "protein_2": "IGHG2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1976094, 1678540], "include_positive": false}}
+{"question_id": "PPIL2-0253", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- FAM91A1 and OR2T34: no interaction detected\n- RORA and IGLON5: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FAM91A1", "protein_2": "OR2T34", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RORA", "protein_2": "IGLON5", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2104679, 1749123], "include_positive": false}}
+{"question_id": "PPIL2-0254", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TMEM72 and PTCD3: no interaction detected\n- AKR1B15 and TNFAIP8: no interaction detected\n- DYNC1I2 and CNOT9: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TMEM72", "protein_2": "PTCD3", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "AKR1B15", "protein_2": "TNFAIP8", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "DYNC1I2", "protein_2": "CNOT9", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1737024, 1768046, 1301407], "include_positive": false}}
+{"question_id": "PPIL2-0255", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PEX5L and SPRR4: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PEX5L", "protein_2": "SPRR4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2156477], "include_positive": true}}
+{"question_id": "PPIL2-0256", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ETV1 and HMGN2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ETV1", "protein_2": "HMGN2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1879194], "include_positive": true}}
+{"question_id": "PPIL2-0257", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PLEKHG2 and ZFP14: no interaction detected\n- H3C15 and TAGAP: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PLEKHG2", "protein_2": "ZFP14", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "H3C15", "protein_2": "TAGAP", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [488541, 2131584], "include_positive": true}}
+{"question_id": "PPIL2-0258", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- KCNA4 and NDUFAF4: no interaction detected\n- E2F6 and INS: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KCNA4", "protein_2": "NDUFAF4", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "E2F6", "protein_2": "INS", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [182457, 1837645], "include_positive": false}}
+{"question_id": "PPIL2-0259", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- GTF2A2 and SMAD1: no interaction detected\n- NAA15 and GABRB3: no interaction detected\n- SNAPIN and MED9: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GTF2A2", "protein_2": "SMAD1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NAA15", "protein_2": "GABRB3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SNAPIN", "protein_2": "MED9", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1041745, 1424507, 1022185], "include_positive": false}}
+{"question_id": "PPIL2-0260", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TRMT11 and KAT8: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRMT11", "protein_2": "KAT8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [908413], "include_positive": false}}
+{"question_id": "PPIL2-0261", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- USP17L12 and KMT5A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "USP17L12", "protein_2": "KMT5A", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1767853], "include_positive": false}}
+{"question_id": "PPIL2-0262", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- FADD and AURKAIP1: no interaction detected\n- KRT10 and ATP8B3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FADD", "protein_2": "AURKAIP1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KRT10", "protein_2": "ATP8B3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1682079, 1330704], "include_positive": false}}
+{"question_id": "PPIL2-0263", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- S100A10 and NACA: no interaction detected\n- PPP1R2C and C5orf24: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "S100A10", "protein_2": "NACA", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PPP1R2C", "protein_2": "C5orf24", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1134294, 45727], "include_positive": false}}
+{"question_id": "PPIL2-0264", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- GRIN2B and PIGG: no interaction detected\n- GNPDA1 and CD300LG: no interaction detected\n- SLC46A2 and SCN1A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GRIN2B", "protein_2": "PIGG", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "GNPDA1", "protein_2": "CD300LG", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SLC46A2", "protein_2": "SCN1A", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [660510, 220841, 1961378], "include_positive": false}}
+{"question_id": "PPIL2-0265", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CHRNB4 and ABCC8: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHRNB4", "protein_2": "ABCC8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [826222], "include_positive": true}}
+{"question_id": "PPIL2-0266", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CLEC2A and CDC14A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLEC2A", "protein_2": "CDC14A", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2120345], "include_positive": false}}
+{"question_id": "PPIL2-0267", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TLE6 and C1QA: no interaction detected\n- CCDC78 and XRCC4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TLE6", "protein_2": "C1QA", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CCDC78", "protein_2": "XRCC4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [611266, 9125], "include_positive": false}}
+{"question_id": "PPIL2-0268", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PIK3CG and CHRNA7: no interaction detected\n- LDHA and SKA1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PIK3CG", "protein_2": "CHRNA7", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "LDHA", "protein_2": "SKA1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1373682, 939503], "include_positive": false}}
+{"question_id": "PPIL2-0269", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- MPP2 and PPP3R2: no interaction detected\n- APOBEC1 and ITGA9: no interaction detected\n- IGHG4 and CEP192: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MPP2", "protein_2": "PPP3R2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "APOBEC1", "protein_2": "ITGA9", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "IGHG4", "protein_2": "CEP192", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [304852, 572978, 1516189], "include_positive": false}}
+{"question_id": "PPIL2-0270", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CD8A and TLN1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CD8A", "protein_2": "TLN1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1632995], "include_positive": false}}
+{"question_id": "PPIL2-0271", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RNASEL and GSC: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNASEL", "protein_2": "GSC", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2000908], "include_positive": true}}
+{"question_id": "PPIL2-0272", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDC23 and DYNC1H1: no interaction detected\n- SLC47A1 and MAMLD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDC23", "protein_2": "DYNC1H1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SLC47A1", "protein_2": "MAMLD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1463814, 2043733], "include_positive": false}}
+{"question_id": "PPIL2-0273", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CFAP65 and ABHD8: no interaction detected\n- TRAF3 and MSH6: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CFAP65", "protein_2": "ABHD8", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "TRAF3", "protein_2": "MSH6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [381987, 725194], "include_positive": false}}
+{"question_id": "PPIL2-0274", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT5B and STT3A: no interaction detected\n- MED25 and CIAO2A: no interaction detected\n- CDK6 and CLPX: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT5B", "protein_2": "STT3A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MED25", "protein_2": "CIAO2A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CDK6", "protein_2": "CLPX", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1565308, 858857, 587437], "include_positive": true}}
+{"question_id": "PPIL2-0275", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PROSER2 and FOLR2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PROSER2", "protein_2": "FOLR2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1908335], "include_positive": false}}
+{"question_id": "PPIL2-0276", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- RPA2 and TTC9C: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RPA2", "protein_2": "TTC9C", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [167601], "include_positive": false}}
+{"question_id": "PPIL2-0277", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PRKRA and CREBZF: no interaction detected\n- PTPMT1 and SMOC1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PRKRA", "protein_2": "CREBZF", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PTPMT1", "protein_2": "SMOC1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1574611, 439351], "include_positive": false}}
+{"question_id": "PPIL2-0278", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CENPS and CHST14: no interaction detected\n- AP1S2 and BAZ1A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CENPS", "protein_2": "CHST14", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "AP1S2", "protein_2": "BAZ1A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2162460, 1325484], "include_positive": true}}
+{"question_id": "PPIL2-0279", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TP73 and ASAH1: no interaction detected\n- CCNL2 and JAK1: no interaction detected\n- RAP2B and F5H3D4: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TP73", "protein_2": "ASAH1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CCNL2", "protein_2": "JAK1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RAP2B", "protein_2": "F5H3D4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1805024, 908725, 1772275], "include_positive": false}}
+{"question_id": "PPIL2-0280", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- NF2 and GET4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NF2", "protein_2": "GET4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [206403], "include_positive": false}}
+{"question_id": "PPIL2-0281", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KARS1 and CHRNA7: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KARS1", "protein_2": "CHRNA7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1277436], "include_positive": false}}
+{"question_id": "PPIL2-0282", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SCT and LIPJ: no interaction detected\n- FAM25C and RHOT2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SCT", "protein_2": "LIPJ", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "FAM25C", "protein_2": "RHOT2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1890088, 20453], "include_positive": false}}
+{"question_id": "PPIL2-0283", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ZFYVE26 and SLC13A3: no interaction detected\n- NDOR1 and CALY: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZFYVE26", "protein_2": "SLC13A3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "NDOR1", "protein_2": "CALY", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [360170, 2235485], "include_positive": false}}
+{"question_id": "PPIL2-0284", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PDYN and ARK2C: no interaction detected\n- GLI1 and CEBPB: no interaction detected\n- TRAC and GABRB2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PDYN", "protein_2": "ARK2C", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "GLI1", "protein_2": "CEBPB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRAC", "protein_2": "GABRB2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1869725, 659115, 598582], "include_positive": false}}
+{"question_id": "PPIL2-0285", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PPP1R26 and RNF38: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PPP1R26", "protein_2": "RNF38", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2096248], "include_positive": false}}
+{"question_id": "PPIL2-0286", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CFAP65 and HIPK4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CFAP65", "protein_2": "HIPK4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [381976], "include_positive": false}}
+{"question_id": "PPIL2-0287", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PLPP6 and ANKK1: no interaction detected\n- SCG3 and CFAP97: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PLPP6", "protein_2": "ANKK1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SCG3", "protein_2": "CFAP97", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [407782, 2191451], "include_positive": false}}
+{"question_id": "PPIL2-0288", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- AP1S1 and NUBP1: no interaction detected\n- ORC2 and CDK5R1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AP1S1", "protein_2": "NUBP1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ORC2", "protein_2": "CDK5R1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1307711, 726912], "include_positive": true}}
+{"question_id": "PPIL2-0289", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PFDN6 and PDGFB: no interaction detected\n- DARS1 and EMC6: no interaction detected\n- DEK and IFT25: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PFDN6", "protein_2": "PDGFB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DARS1", "protein_2": "EMC6", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DEK", "protein_2": "IFT25", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1340038, 1605154, 1408391], "include_positive": false}}
+{"question_id": "PPIL2-0290", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- LCE1D and ULBP2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LCE1D", "protein_2": "ULBP2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [351636], "include_positive": false}}
+{"question_id": "PPIL2-0291", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- LDAF1 and RNH1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LDAF1", "protein_2": "RNH1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [160273], "include_positive": false}}
+{"question_id": "PPIL2-0292", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CASS4 and RBAK: no interaction detected\n- UBE2C and DPPA3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CASS4", "protein_2": "RBAK", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "UBE2C", "protein_2": "DPPA3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [492212, 34221], "include_positive": true}}
+{"question_id": "PPIL2-0293", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CNOT9 and ATF5: no interaction detected\n- SLC10A2 and NEDD9: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CNOT9", "protein_2": "ATF5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SLC10A2", "protein_2": "NEDD9", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1717854, 2036744], "include_positive": false}}
+{"question_id": "PPIL2-0294", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT5B and DHDDS: no interaction detected\n- SDC1 and INCENP: no interaction detected\n- MRPS18B and MDH1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT5B", "protein_2": "DHDDS", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SDC1", "protein_2": "INCENP", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MRPS18B", "protein_2": "MDH1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1414007, 1074421, 1436422], "include_positive": true}}
+{"question_id": "PPIL2-0295", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GMNN and UMPS: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GMNN", "protein_2": "UMPS", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1838300], "include_positive": true}}
+{"question_id": "PPIL2-0296", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDC37 and TAPBP: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDC37", "protein_2": "TAPBP", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [582091], "include_positive": false}}
+{"question_id": "PPIL2-0297", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TEX11 and SLC7A6: no interaction detected\n- RTRAF and EIF3L: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TEX11", "protein_2": "SLC7A6", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "RTRAF", "protein_2": "EIF3L", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [408813, 1182099], "include_positive": false}}
+{"question_id": "PPIL2-0298", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HEXB and ATP6V1C2: no interaction detected\n- YEATS4 and DLG1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HEXB", "protein_2": "ATP6V1C2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "YEATS4", "protein_2": "DLG1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [723279, 1513376], "include_positive": false}}
+{"question_id": "PPIL2-0299", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SS18 and RPP38: no interaction detected\n- URI1 and F13A1: no interaction detected\n- DNTTIP1 and ATP10D: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SS18", "protein_2": "RPP38", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "URI1", "protein_2": "F13A1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DNTTIP1", "protein_2": "ATP10D", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1466393, 1329503, 1123853], "include_positive": true}}
+{"question_id": "PPIL2-0300", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- NXPE2 and MRAP: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NXPE2", "protein_2": "MRAP", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2184706], "include_positive": false}}
+{"question_id": "PPIL2-0301", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BORCS8 and DIS3L: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BORCS8", "protein_2": "DIS3L", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1443949], "include_positive": true}}
+{"question_id": "PPIL2-0302", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- VPS25 and EIF4G3: no interaction detected\n- DNAJB1 and CDC14A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VPS25", "protein_2": "EIF4G3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DNAJB1", "protein_2": "CDC14A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1086497, 188254], "include_positive": false}}
+{"question_id": "PPIL2-0303", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ITGB1 and TRMT112: no interaction detected\n- KRTAP5-8 and KAZALD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ITGB1", "protein_2": "TRMT112", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KRTAP5-8", "protein_2": "KAZALD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [920674, 1841087], "include_positive": false}}
+{"question_id": "PPIL2-0304", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ASB12 and SLC28A2: no interaction detected\n- CCT8 and ZNF501: no interaction detected\n- TLE6 and PATJ: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ASB12", "protein_2": "SLC28A2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CCT8", "protein_2": "ZNF501", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "TLE6", "protein_2": "PATJ", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1818989, 1986602, 757788], "include_positive": false}}
+{"question_id": "PPIL2-0305", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- LATS1 and FCER1G: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LATS1", "protein_2": "FCER1G", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1862719], "include_positive": false}}
+{"question_id": "PPIL2-0306", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LDHA and TRGC2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LDHA", "protein_2": "TRGC2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [735569], "include_positive": true}}
+{"question_id": "PPIL2-0307", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CLC and NRP1: no interaction detected\n- AIMP2 and TOMM5: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLC", "protein_2": "NRP1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "AIMP2", "protein_2": "TOMM5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1795906, 1594293], "include_positive": false}}
+{"question_id": "PPIL2-0308", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TAF12 and PCDHB14: no interaction detected\n- ZDHHC16 and UBE2E2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TAF12", "protein_2": "PCDHB14", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "ZDHHC16", "protein_2": "UBE2E2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [323133, 450653], "include_positive": true}}
+{"question_id": "PPIL2-0309", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- DPEP1 and ARHGEF1: no interaction detected\n- SMPX and CPNE5: no interaction detected\n- TERF1 and CADM2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DPEP1", "protein_2": "ARHGEF1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "SMPX", "protein_2": "CPNE5", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "TERF1", "protein_2": "CADM2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [169179, 2230883, 1995146], "include_positive": false}}
+{"question_id": "PPIL2-0310", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- UBQLNL and SIRT4: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "UBQLNL", "protein_2": "SIRT4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2157759], "include_positive": false}}
+{"question_id": "PPIL2-0311", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MTX2 and ACTB: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MTX2", "protein_2": "ACTB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [816906], "include_positive": true}}
+{"question_id": "PPIL2-0312", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDK7 and GP5: no interaction detected\n- BLOC1S2 and INTS1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDK7", "protein_2": "GP5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "BLOC1S2", "protein_2": "INTS1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1685626, 771476], "include_positive": false}}
+{"question_id": "PPIL2-0313", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RBM8A and PATJ: no interaction detected\n- CREB1 and EXOC8: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM8A", "protein_2": "PATJ", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CREB1", "protein_2": "EXOC8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [623442, 1032652], "include_positive": false}}
+{"question_id": "PPIL2-0314", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ACTL6B and MED26: no interaction detected\n- TRMT10B and BACH2: no interaction detected\n- KLHDC8B and MT1HL1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ACTL6B", "protein_2": "MED26", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRMT10B", "protein_2": "BACH2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KLHDC8B", "protein_2": "MT1HL1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1126842, 1599172, 1896731], "include_positive": true}}
+{"question_id": "PPIL2-0315", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NLRP5 and PARD6B: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NLRP5", "protein_2": "PARD6B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [949279], "include_positive": true}}
+{"question_id": "PPIL2-0316", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MED19 and CREBZF: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MED19", "protein_2": "CREBZF", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [555941], "include_positive": true}}
+{"question_id": "PPIL2-0317", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MTREX and NAA30: no interaction detected\n- DMRT3 and DDX49: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MTREX", "protein_2": "NAA30", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DMRT3", "protein_2": "DDX49", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1701374, 492426], "include_positive": false}}
+{"question_id": "PPIL2-0318", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- VCL and ATF6B: no interaction detected\n- KATNB1 and FANCE: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VCL", "protein_2": "ATF6B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KATNB1", "protein_2": "FANCE", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1364326, 1121232], "include_positive": false}}
+{"question_id": "PPIL2-0319", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MED19 and BACH1: no interaction detected\n- AP2A2 and ITGA1: no interaction detected\n- CNOT4 and LAMA2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MED19", "protein_2": "BACH1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "AP2A2", "protein_2": "ITGA1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CNOT4", "protein_2": "LAMA2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [809025, 1476378, 1387256], "include_positive": true}}
+{"question_id": "PPIL2-0320", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMARCC1 and MCM3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMARCC1", "protein_2": "MCM3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [512871], "include_positive": true}}
+{"question_id": "PPIL2-0321", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CLNS1A and DDB1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLNS1A", "protein_2": "DDB1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [508383], "include_positive": false}}
+{"question_id": "PPIL2-0322", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LAMA1 and JAK2: no interaction detected\n- GUCD1 and IFNE: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LAMA1", "protein_2": "JAK2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "GUCD1", "protein_2": "IFNE", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [781387, 2146880], "include_positive": false}}
+{"question_id": "PPIL2-0323", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- INTS10 and MTA3: no interaction detected\n- PSTPIP1 and RPL8: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "INTS10", "protein_2": "MTA3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PSTPIP1", "protein_2": "RPL8", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [587439, 1814821], "include_positive": false}}
+{"question_id": "PPIL2-0324", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KANSL1 and AP3B2: no interaction detected\n- MX1 and M0QYV0: no interaction detected\n- MAFF and IDH3G: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KANSL1", "protein_2": "AP3B2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MX1", "protein_2": "M0QYV0", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MAFF", "protein_2": "IDH3G", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1013628, 1781450, 1594027], "include_positive": false}}
+{"question_id": "PPIL2-0325", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SPAG1 and SUPT20H: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SPAG1", "protein_2": "SUPT20H", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [714584], "include_positive": true}}
+{"question_id": "PPIL2-0326", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- GAL and CD163: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GAL", "protein_2": "CD163", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [182608], "include_positive": false}}
+{"question_id": "PPIL2-0327", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TRAPPC5 and TIMM21: no interaction detected\n- RUVBL1 and MRPS12: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRAPPC5", "protein_2": "TIMM21", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RUVBL1", "protein_2": "MRPS12", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1510723, 1516319], "include_positive": false}}
+{"question_id": "PPIL2-0328", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- EIF3C and TCEAL2: no interaction detected\n- OR5B17 and MFSD6L: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EIF3C", "protein_2": "TCEAL2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "OR5B17", "protein_2": "MFSD6L", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2214588, 2153345], "include_positive": true}}
+{"question_id": "PPIL2-0329", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- DRC8 and SYNE3: no interaction detected\n- CAB39L and MRGBP: no interaction detected\n- IGLC3 and IBA57: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DRC8", "protein_2": "SYNE3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CAB39L", "protein_2": "MRGBP", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "IGLC3", "protein_2": "IBA57", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [355475, 860106, 1501451], "include_positive": false}}
+{"question_id": "PPIL2-0330", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DEPDC5 and EIF4G1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DEPDC5", "protein_2": "EIF4G1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [705138], "include_positive": false}}
+{"question_id": "PPIL2-0331", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP1A1 and TAF3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP1A1", "protein_2": "TAF3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1581498], "include_positive": false}}
+{"question_id": "PPIL2-0332", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RPN2 and IFT80: no interaction detected\n- PIK3R3 and GABRA4: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RPN2", "protein_2": "IFT80", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PIK3R3", "protein_2": "GABRA4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1630862, 1385636], "include_positive": true}}
+{"question_id": "PPIL2-0333", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SGSM3 and BACH2: no interaction detected\n- BLOC1S2 and RAD9A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SGSM3", "protein_2": "BACH2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "BLOC1S2", "protein_2": "RAD9A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2205218, 809816], "include_positive": false}}
+{"question_id": "PPIL2-0334", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- COMP and NACC1: no interaction detected\n- PIMREG and C19orf73: no interaction detected\n- CLDN2 and GAS2L3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COMP", "protein_2": "NACC1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PIMREG", "protein_2": "C19orf73", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CLDN2", "protein_2": "GAS2L3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1982678, 476672, 250163], "include_positive": false}}
+{"question_id": "PPIL2-0335", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- NIPA1 and RTN4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NIPA1", "protein_2": "RTN4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [386910], "include_positive": false}}
+{"question_id": "PPIL2-0336", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- VCAM1 and MTR: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VCAM1", "protein_2": "MTR", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1920350], "include_positive": false}}
+{"question_id": "PPIL2-0337", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMARCD2 and AP3D1: no interaction detected\n- NPPA and ENDOU: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMARCD2", "protein_2": "AP3D1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NPPA", "protein_2": "ENDOU", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [651064, 1869521], "include_positive": true}}
+{"question_id": "PPIL2-0338", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COL1A2 and THUMPD2: no interaction detected\n- KCTD21 and NDFIP1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COL1A2", "protein_2": "THUMPD2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KCTD21", "protein_2": "NDFIP1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [817748, 337005], "include_positive": true}}
+{"question_id": "PPIL2-0339", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATXN7L3 and GABBR1: no interaction detected\n- UBXN2A and PTCD3: no interaction detected\n- NR4A1 and VSIG10L: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATXN7L3", "protein_2": "GABBR1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "UBXN2A", "protein_2": "PTCD3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "NR4A1", "protein_2": "VSIG10L", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1374613, 265433, 1928743], "include_positive": false}}
+{"question_id": "PPIL2-0340", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- MELTF and MRPL18: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MELTF", "protein_2": "MRPL18", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1886459], "include_positive": true}}
+{"question_id": "PPIL2-0341", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TOMM7 and TAF5: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TOMM7", "protein_2": "TAF5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1556540], "include_positive": false}}
+{"question_id": "PPIL2-0342", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDK7 and ITGA11: no interaction detected\n- LENG9 and THAP9: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDK7", "protein_2": "ITGA11", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "LENG9", "protein_2": "THAP9", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1234892, 2199489], "include_positive": false}}
+{"question_id": "PPIL2-0343", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TSC2 and NBAS: no interaction detected\n- FBXW10 and SARAF: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSC2", "protein_2": "NBAS", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "FBXW10", "protein_2": "SARAF", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1605285, 2103995], "include_positive": false}}
+{"question_id": "PPIL2-0344", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RBCK1 and SAP130: no interaction detected\n- TIMM10B and TSPAN3: no interaction detected\n- RAD50 and SPTSSB: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBCK1", "protein_2": "SAP130", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TIMM10B", "protein_2": "TSPAN3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "RAD50", "protein_2": "SPTSSB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [749523, 22831, 1440875], "include_positive": false}}
+{"question_id": "PPIL2-0345", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- VPS53 and PPP1R3F: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VPS53", "protein_2": "PPP1R3F", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2099337], "include_positive": false}}
+{"question_id": "PPIL2-0346", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- HDAC8 and DNAH5: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HDAC8", "protein_2": "DNAH5", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2186515], "include_positive": true}}
+{"question_id": "PPIL2-0347", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- APH1A and CACNA2D1: no interaction detected\n- SNX32 and TMEM167A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "APH1A", "protein_2": "CACNA2D1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SNX32", "protein_2": "TMEM167A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1243862, 399400], "include_positive": false}}
+{"question_id": "PPIL2-0348", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DEK and CCNB2: no interaction detected\n- PHF20 and MAST4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DEK", "protein_2": "CCNB2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PHF20", "protein_2": "MAST4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1504360, 1799956], "include_positive": false}}
+{"question_id": "PPIL2-0349", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PATJ and KANSL3: no interaction detected\n- UFD1 and APC: no interaction detected\n- PFDN6 and IFT81: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PATJ", "protein_2": "KANSL3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "UFD1", "protein_2": "APC", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PFDN6", "protein_2": "IFT81", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [745240, 615690, 1584662], "include_positive": false}}
+{"question_id": "PPIL2-0350", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RAD9A and KCNIP2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RAD9A", "protein_2": "KCNIP2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [770784], "include_positive": true}}
+{"question_id": "PPIL2-0351", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BRCC3 and MT-ATP8: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BRCC3", "protein_2": "MT-ATP8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1101341], "include_positive": false}}
+{"question_id": "PPIL2-0352", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BID and INTS9: no interaction detected\n- SFTPA1 and CCDC142: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BID", "protein_2": "INTS9", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SFTPA1", "protein_2": "CCDC142", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1083652, 2069318], "include_positive": true}}
+{"question_id": "PPIL2-0353", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- DYNC1I1 and CHRDL2: no interaction detected\n- CHRNB3 and RMI1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DYNC1I1", "protein_2": "CHRDL2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CHRNB3", "protein_2": "RMI1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [36957, 1429920], "include_positive": true}}
+{"question_id": "PPIL2-0354", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- DDIT3 and ATP5F1EP2: no interaction detected\n- NLRC4 and SGCE: no interaction detected\n- ERICH1 and LLPH: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DDIT3", "protein_2": "ATP5F1EP2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NLRC4", "protein_2": "SGCE", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ERICH1", "protein_2": "LLPH", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [544403, 1292451, 399172], "include_positive": true}}
+{"question_id": "PPIL2-0355", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ME1 and SHLD2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ME1", "protein_2": "SHLD2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1150702], "include_positive": false}}
+{"question_id": "PPIL2-0356", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TULP3 and RHOBTB1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TULP3", "protein_2": "RHOBTB1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1836127], "include_positive": true}}
+{"question_id": "PPIL2-0357", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SLC8A3 and ACCS: no interaction detected\n- TAF9 and HPS6: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLC8A3", "protein_2": "ACCS", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "TAF9", "protein_2": "HPS6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [249612, 535646], "include_positive": true}}
+{"question_id": "PPIL2-0358", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NCBP1 and MAGOHB: no interaction detected\n- TYK2 and GABRA5: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NCBP1", "protein_2": "MAGOHB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TYK2", "protein_2": "GABRA5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [834960, 1369102], "include_positive": true}}
+{"question_id": "PPIL2-0359", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- NKX2-6 and ZNG1B: no interaction detected\n- LYG2 and Q5VWM5: no interaction detected\n- IFNA8 and SHISAL2A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NKX2-6", "protein_2": "ZNG1B", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "LYG2", "protein_2": "Q5VWM5", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "IFNA8", "protein_2": "SHISAL2A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1744855, 2101751, 203532], "include_positive": true}}
+{"question_id": "PPIL2-0360", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NABP2 and CENPC: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NABP2", "protein_2": "CENPC", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1577459], "include_positive": false}}
+{"question_id": "PPIL2-0361", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- FDCSP and REV1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FDCSP", "protein_2": "REV1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2177284], "include_positive": true}}
+{"question_id": "PPIL2-0362", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GBP5 and ELANE: no interaction detected\n- COL11A2 and IMMT: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GBP5", "protein_2": "ELANE", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "COL11A2", "protein_2": "IMMT", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1885578, 1170155], "include_positive": true}}
+{"question_id": "PPIL2-0363", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- MFHAS1 and UNG: no interaction detected\n- VTN and CD3G: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MFHAS1", "protein_2": "UNG", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "VTN", "protein_2": "CD3G", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1905688, 717241], "include_positive": false}}
+{"question_id": "PPIL2-0364", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TRIP13 and KLRF1: no interaction detected\n- PPP1R21 and DOP1A: no interaction detected\n- FASN and TSHZ2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRIP13", "protein_2": "KLRF1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PPP1R21", "protein_2": "DOP1A", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "FASN", "protein_2": "TSHZ2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [318636, 2089683, 225693], "include_positive": false}}
+{"question_id": "PPIL2-0365", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SUPV3L1 and SLF1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SUPV3L1", "protein_2": "SLF1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1117179], "include_positive": false}}
+{"question_id": "PPIL2-0366", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CCT6A and ITGAX: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CCT6A", "protein_2": "ITGAX", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1358917], "include_positive": false}}
+{"question_id": "PPIL2-0367", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- IRAK1BP1 and RPS4X: no interaction detected\n- ATP6V1B2 and IGHA2: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IRAK1BP1", "protein_2": "RPS4X", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ATP6V1B2", "protein_2": "IGHA2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2010727, 936972], "include_positive": true}}
+{"question_id": "PPIL2-0368", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CDK17 and VTCN1: no interaction detected\n- ABRAXAS1 and CCNB1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDK17", "protein_2": "VTCN1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ABRAXAS1", "protein_2": "CCNB1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2019692, 670418], "include_positive": false}}
+{"question_id": "PPIL2-0369", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDC45 and NSFL1C: no interaction detected\n- NSMCE2 and PLRG1: no interaction detected\n- PLEKHA2 and DCAF13: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDC45", "protein_2": "NSFL1C", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NSMCE2", "protein_2": "PLRG1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PLEKHA2", "protein_2": "DCAF13", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [814353, 867546, 2230150], "include_positive": true}}
+{"question_id": "PPIL2-0370", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- XRCC5 and BCL9: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "XRCC5", "protein_2": "BCL9", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1788708], "include_positive": false}}
+{"question_id": "PPIL2-0371", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- IFNGR1 and AIMP1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IFNGR1", "protein_2": "AIMP1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1533542], "include_positive": false}}
+{"question_id": "PPIL2-0372", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- YPEL2 and TP53INP2: no interaction detected\n- SNRPD1 and EIF4G1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "YPEL2", "protein_2": "TP53INP2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SNRPD1", "protein_2": "EIF4G1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2154906, 739023], "include_positive": true}}
+{"question_id": "PPIL2-0373", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BACH2 and BLM: no interaction detected\n- FNDC8 and SPACA1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BACH2", "protein_2": "BLM", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "FNDC8", "protein_2": "SPACA1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1338423, 434649], "include_positive": false}}
+{"question_id": "PPIL2-0374", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- VPS33B and STAG3: no interaction detected\n- CDK16 and MNAT1: no interaction detected\n- SYN3 and BORCS6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VPS33B", "protein_2": "STAG3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CDK16", "protein_2": "MNAT1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SYN3", "protein_2": "BORCS6", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1660282, 1453587, 45859], "include_positive": false}}
+{"question_id": "PPIL2-0375", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- PHOSPHO1 and TSPYL4: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PHOSPHO1", "protein_2": "TSPYL4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [435143], "include_positive": false}}
+{"question_id": "PPIL2-0376", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ERP29 and TMEM134: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ERP29", "protein_2": "TMEM134", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1941476], "include_positive": false}}
+{"question_id": "PPIL2-0377", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- UXT and COQ5: no interaction detected\n- NFIL3 and TTI1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "UXT", "protein_2": "COQ5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NFIL3", "protein_2": "TTI1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1458938, 610070], "include_positive": false}}
+{"question_id": "PPIL2-0378", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CACNA1S and CENPS: no interaction detected\n- CRTC1 and OTOG: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CACNA1S", "protein_2": "CENPS", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CRTC1", "protein_2": "OTOG", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1149959, 2120205], "include_positive": true}}
+{"question_id": "PPIL2-0379", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMARCA1 and TRRAP: no interaction detected\n- PMF1 and STT3A: no interaction detected\n- TRMT61B and ALCAM: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMARCA1", "protein_2": "TRRAP", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PMF1", "protein_2": "STT3A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRMT61B", "protein_2": "ALCAM", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [984216, 1439925, 2046093], "include_positive": true}}
+{"question_id": "PPIL2-0380", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CYTIP and CAND2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CYTIP", "protein_2": "CAND2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [78095], "include_positive": false}}
+{"question_id": "PPIL2-0381", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- LCE2D and HMGCS2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LCE2D", "protein_2": "HMGCS2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1996567], "include_positive": false}}
+{"question_id": "PPIL2-0382", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TIMM8A and COPS7B: no interaction detected\n- ADGRF4 and DDX19B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TIMM8A", "protein_2": "COPS7B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ADGRF4", "protein_2": "DDX19B", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [580479, 411390], "include_positive": false}}
+{"question_id": "PPIL2-0383", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LPL and BICRA: no interaction detected\n- NTN4 and TMPRSS11B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LPL", "protein_2": "BICRA", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NTN4", "protein_2": "TMPRSS11B", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1182073, 2141817], "include_positive": false}}
+{"question_id": "PPIL2-0384", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- FGF17 and DEUP1: no interaction detected\n- NR4A2 and RIPK4: no interaction detected\n- CDC37 and CD8B: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FGF17", "protein_2": "DEUP1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "NR4A2", "protein_2": "RIPK4", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CDC37", "protein_2": "CD8B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [72240, 217508, 1450510], "include_positive": false}}
+{"question_id": "PPIL2-0385", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- NR4A2 and CERS6: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NR4A2", "protein_2": "CERS6", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [217536], "include_positive": false}}
+{"question_id": "PPIL2-0386", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RXRB and POP7: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RXRB", "protein_2": "POP7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1300556], "include_positive": false}}
+{"question_id": "PPIL2-0387", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- RBM22 and RRP9: no interaction detected\n- F3 and KCNIP1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RBM22", "protein_2": "RRP9", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "F3", "protein_2": "KCNIP1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1818158, 524780], "include_positive": false}}
+{"question_id": "PPIL2-0388", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- FBXL2 and AFG2B: no interaction detected\n- ATP6V0D1 and ARID1A: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FBXL2", "protein_2": "AFG2B", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ATP6V0D1", "protein_2": "ARID1A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2220006, 1115192], "include_positive": false}}
+{"question_id": "PPIL2-0389", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LAMA4 and TSHB: no interaction detected\n- ITGB5 and COL4A4: no interaction detected\n- LEF1 and PAGR1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LAMA4", "protein_2": "TSHB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ITGB5", "protein_2": "COL4A4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "LEF1", "protein_2": "PAGR1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1517544, 1331228, 1146618], "include_positive": false}}
+{"question_id": "PPIL2-0390", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BRIP1 and IARS1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BRIP1", "protein_2": "IARS1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1729402], "include_positive": false}}
+{"question_id": "PPIL2-0391", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT3 and TADA2B: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT3", "protein_2": "TADA2B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [684299], "include_positive": true}}
+{"question_id": "PPIL2-0392", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- INTS9 and MTOR: no interaction detected\n- SNRPD3 and TAF11: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "INTS9", "protein_2": "MTOR", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SNRPD3", "protein_2": "TAF11", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [658841, 1671692], "include_positive": false}}
+{"question_id": "PPIL2-0393", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- IGSF23 and FBXO31: no interaction detected\n- SMARCD3 and IGLC6: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IGSF23", "protein_2": "FBXO31", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SMARCD3", "protein_2": "IGLC6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1738395, 1543736], "include_positive": false}}
+{"question_id": "PPIL2-0394", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CENPT and POP4: no interaction detected\n- LAPTM4B and OR9A2: no interaction detected\n- ITGB5 and NCOA6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CENPT", "protein_2": "POP4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "LAPTM4B", "protein_2": "OR9A2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "ITGB5", "protein_2": "NCOA6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1417177, 2145225, 1501081], "include_positive": false}}
+{"question_id": "PPIL2-0395", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- STAT3 and IFT70B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STAT3", "protein_2": "IFT70B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1637228], "include_positive": false}}
+{"question_id": "PPIL2-0396", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- KCNK1 and METTL25B: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KCNK1", "protein_2": "METTL25B", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1783552], "include_positive": false}}
+{"question_id": "PPIL2-0397", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- NXT2 and CYBA: no interaction detected\n- RARS1 and TAF5: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "NXT2", "protein_2": "CYBA", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RARS1", "protein_2": "TAF5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [910930, 1364753], "include_positive": true}}
+{"question_id": "PPIL2-0398", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LHB and SUPT3H: no interaction detected\n- HOXD10 and C9orf72: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LHB", "protein_2": "SUPT3H", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HOXD10", "protein_2": "C9orf72", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1616166, 1395097], "include_positive": false}}
+{"question_id": "PPIL2-0399", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- VPS18 and MAFF: no interaction detected\n- PSMA4 and CRYBB3: no interaction detected\n- SMARCD1 and TFB2M: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "VPS18", "protein_2": "MAFF", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PSMA4", "protein_2": "CRYBB3", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SMARCD1", "protein_2": "TFB2M", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1086610, 1934339, 1710717], "include_positive": false}}
+{"question_id": "PPIL2-0400", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- REP15 and ZNF107: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "REP15", "protein_2": "ZNF107", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [361800], "include_positive": false}}
+{"question_id": "PPIL2-0401", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- FADD and CACNB1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FADD", "protein_2": "CACNB1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1464087], "include_positive": true}}
+{"question_id": "PPIL2-0402", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ZNF12 and HCST: no interaction detected\n- ERGIC2 and PIK3R5: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZNF12", "protein_2": "HCST", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "ERGIC2", "protein_2": "PIK3R5", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [169977, 874584], "include_positive": false}}
+{"question_id": "PPIL2-0403", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- EIF3I and VPS51: no interaction detected\n- AP1B1 and NCOA6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EIF3I", "protein_2": "VPS51", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "AP1B1", "protein_2": "NCOA6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1402844, 1268423], "include_positive": false}}
+{"question_id": "PPIL2-0404", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BARD1 and DDX23: no interaction detected\n- SPSB3 and FARSA: no interaction detected\n- RABGGTA and RNASEH2A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BARD1", "protein_2": "DDX23", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SPSB3", "protein_2": "FARSA", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "RABGGTA", "protein_2": "RNASEH2A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1633019, 372343, 1581128], "include_positive": false}}
+{"question_id": "PPIL2-0405", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KRT36 and TAF7: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KRT36", "protein_2": "TAF7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1236749], "include_positive": false}}
+{"question_id": "PPIL2-0406", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SPMIP6 and RAB1B: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SPMIP6", "protein_2": "RAB1B", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [426323], "include_positive": false}}
+{"question_id": "PPIL2-0407", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TOP3B and SNRPA1: no interaction detected\n- ATP5MC3 and MVB12B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TOP3B", "protein_2": "SNRPA1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ATP5MC3", "protein_2": "MVB12B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1033766, 1065454], "include_positive": false}}
+{"question_id": "PPIL2-0408", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CHCHD1 and GEMIN8: no interaction detected\n- TCL1A and CD200R1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CHCHD1", "protein_2": "GEMIN8", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TCL1A", "protein_2": "CD200R1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1528650, 246900], "include_positive": false}}
+{"question_id": "PPIL2-0409", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HBD and INO80: no interaction detected\n- MAFG and KMT2D: no interaction detected\n- SLC18A3 and GABRQ: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HBD", "protein_2": "INO80", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "MAFG", "protein_2": "KMT2D", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SLC18A3", "protein_2": "GABRQ", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [647395, 1387295, 324332], "include_positive": false}}
+{"question_id": "PPIL2-0410", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SUV39H1 and CHRNA1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SUV39H1", "protein_2": "CHRNA1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [727227], "include_positive": true}}
+{"question_id": "PPIL2-0411", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TSC1 and SSPN: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSC1", "protein_2": "SSPN", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1261738], "include_positive": false}}
+{"question_id": "PPIL2-0412", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- IL12A and KANSL3: no interaction detected\n- ATP6V1B2 and INTS6: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IL12A", "protein_2": "KANSL3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ATP6V1B2", "protein_2": "INTS6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [916711, 957429], "include_positive": false}}
+{"question_id": "PPIL2-0413", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CFP and POLD4: no interaction detected\n- CSNK2A2 and STT3A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CFP", "protein_2": "POLD4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CSNK2A2", "protein_2": "STT3A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [602347, 1169728], "include_positive": false}}
+{"question_id": "PPIL2-0414", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- MBD3L3 and CBS: no interaction detected\n- MTA1 and CCNT1: no interaction detected\n- SMARCC2 and SF3A1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MBD3L3", "protein_2": "CBS", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "MTA1", "protein_2": "CCNT1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SMARCC2", "protein_2": "SF3A1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [12475, 1117352, 1667049], "include_positive": false}}
+{"question_id": "PPIL2-0415", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- B4GALT1 and A0A088AWK7: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "B4GALT1", "protein_2": "A0A088AWK7", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1732289], "include_positive": true}}
+{"question_id": "PPIL2-0416", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SLC43A2 and PTPRM: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLC43A2", "protein_2": "PTPRM", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1939153], "include_positive": true}}
+{"question_id": "PPIL2-0417", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MCM4 and KPNB1: no interaction detected\n- HRAS and RPTOR: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MCM4", "protein_2": "KPNB1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "HRAS", "protein_2": "RPTOR", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1631442, 801519], "include_positive": false}}
+{"question_id": "PPIL2-0418", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- CDC37 and MRPS14: no interaction detected\n- SF3B2 and FOXD4L1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CDC37", "protein_2": "MRPS14", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SF3B2", "protein_2": "FOXD4L1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1535615, 297271], "include_positive": true}}
+{"question_id": "PPIL2-0419", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- DOCK3 and ALDH1B1: no interaction detected\n- CSNK2B and KANSL1: no interaction detected\n- VAT1L and ZNF175: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DOCK3", "protein_2": "ALDH1B1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "CSNK2B", "protein_2": "KANSL1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "VAT1L", "protein_2": "ZNF175", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1943395, 727543, 2230972], "include_positive": false}}
+{"question_id": "PPIL2-0420", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- MED16 and ADAD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MED16", "protein_2": "ADAD1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2208808], "include_positive": false}}
+{"question_id": "PPIL2-0421", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- FARSB and IFT70B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "FARSB", "protein_2": "IFT70B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1645937], "include_positive": false}}
+{"question_id": "PPIL2-0422", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- MICOS10 and ENAH: no interaction detected\n- PRKAG1 and BCKDHA: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MICOS10", "protein_2": "ENAH", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "PRKAG1", "protein_2": "BCKDHA", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [354136, 1568308], "include_positive": true}}
+{"question_id": "PPIL2-0423", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MED20 and ATP6V1B1: no interaction detected\n- GTPBP10 and CDC34: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MED20", "protein_2": "ATP6V1B1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "GTPBP10", "protein_2": "CDC34", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [902192, 10438], "include_positive": true}}
+{"question_id": "PPIL2-0424", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MTA1 and KCNIP1: no interaction detected\n- TSNAX and ATP8B4: no interaction detected\n- AP1M1 and COLEC11: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MTA1", "protein_2": "KCNIP1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TSNAX", "protein_2": "ATP8B4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "AP1M1", "protein_2": "COLEC11", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [948179, 745676, 1147186], "include_positive": false}}
+{"question_id": "PPIL2-0425", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SDC2 and MAP3K7CL: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SDC2", "protein_2": "MAP3K7CL", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [204905], "include_positive": false}}
+{"question_id": "PPIL2-0426", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- POLA2 and NOTCH1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "POLA2", "protein_2": "NOTCH1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1544262], "include_positive": false}}
+{"question_id": "PPIL2-0427", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- AARSD1 and LINS1: no interaction detected\n- DEFB1 and ERRFI1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AARSD1", "protein_2": "LINS1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "DEFB1", "protein_2": "ERRFI1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2177782, 252304], "include_positive": false}}
+{"question_id": "PPIL2-0428", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- HGS and PHF10: no interaction detected\n- DLGAP3 and CGREF1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "HGS", "protein_2": "PHF10", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "DLGAP3", "protein_2": "CGREF1", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1157027, 115870], "include_positive": false}}
+{"question_id": "PPIL2-0429", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- RNASEK and GATAD2A: no interaction detected\n- SERPINA7 and A4GALT: no interaction detected\n- HCFC1 and NFE2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNASEK", "protein_2": "GATAD2A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SERPINA7", "protein_2": "A4GALT", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "HCFC1", "protein_2": "NFE2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [611616, 1879871, 1728182], "include_positive": false}}
+{"question_id": "PPIL2-0430", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ENTPD4 and KLK3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ENTPD4", "protein_2": "KLK3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1882442], "include_positive": false}}
+{"question_id": "PPIL2-0431", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- CYB5RL and AGAP4: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CYB5RL", "protein_2": "AGAP4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2110131], "include_positive": false}}
+{"question_id": "PPIL2-0432", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COX5A and COQ4: no interaction detected\n- NR0B2 and STK24: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COX5A", "protein_2": "COQ4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NR0B2", "protein_2": "STK24", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1290935, 317007], "include_positive": true}}
+{"question_id": "PPIL2-0433", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP5F1D and AP4B1: no interaction detected\n- TRMT6 and SIRT1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP5F1D", "protein_2": "AP4B1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRMT6", "protein_2": "SIRT1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [701217, 606851], "include_positive": true}}
+{"question_id": "PPIL2-0434", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MYC and NUBP2: no interaction detected\n- FGA and IGKC: no interaction detected\n- PRDM15 and TSSK4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MYC", "protein_2": "NUBP2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "FGA", "protein_2": "IGKC", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PRDM15", "protein_2": "TSSK4", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1327474, 1559172, 2001471], "include_positive": false}}
+{"question_id": "PPIL2-0435", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SCAI and C5AR2: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SCAI", "protein_2": "C5AR2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [2170365], "include_positive": false}}
+{"question_id": "PPIL2-0436", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP5F1E and NFE2L3: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP5F1E", "protein_2": "NFE2L3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [618614], "include_positive": true}}
+{"question_id": "PPIL2-0437", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- RPA2 and TTC39B: no interaction detected\n- C11orf68 and ADCY5: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RPA2", "protein_2": "TTC39B", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "C11orf68", "protein_2": "ADCY5", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [167585, 1859793], "include_positive": true}}
+{"question_id": "PPIL2-0438", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COL11A1 and TTI1: no interaction detected\n- KLRD1 and MRPS15: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COL11A1", "protein_2": "TTI1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KLRD1", "protein_2": "MRPS15", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1062534, 1448715], "include_positive": false}}
+{"question_id": "PPIL2-0439", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- P62158 and KATNA1: no interaction detected\n- PIK3R1 and DBNDD2: no interaction detected\n- PRR23B and PAQR5: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "P62158", "protein_2": "KATNA1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PIK3R1", "protein_2": "DBNDD2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PRR23B", "protein_2": "PAQR5", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [930429, 1937286, 381018], "include_positive": true}}
+{"question_id": "PPIL2-0440", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SH3RF1 and BAIAP2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SH3RF1", "protein_2": "BAIAP2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [391398], "include_positive": false}}
+{"question_id": "PPIL2-0441", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MCM3 and BACH1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MCM3", "protein_2": "BACH1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1609338], "include_positive": false}}
+{"question_id": "PPIL2-0442", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- WWOX and PLEKHF1: no interaction detected\n- TMEM186 and OR5K3: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "WWOX", "protein_2": "PLEKHF1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "TMEM186", "protein_2": "OR5K3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [470372, 1746993], "include_positive": false}}
+{"question_id": "PPIL2-0443", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- COX4I1 and LAMC1: no interaction detected\n- NFYC and INTS7: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "COX4I1", "protein_2": "LAMC1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "NFYC", "protein_2": "INTS7", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1282425, 669237], "include_positive": false}}
+{"question_id": "PPIL2-0444", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CAMK2D and FETUB: no interaction detected\n- TSPAN15 and PIP4P1: no interaction detected\n- POLE3 and DROSHA: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CAMK2D", "protein_2": "FETUB", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "TSPAN15", "protein_2": "PIP4P1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "POLE3", "protein_2": "DROSHA", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [299006, 114748, 1240210], "include_positive": false}}
+{"question_id": "PPIL2-0445", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- LSM2 and SSPN: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LSM2", "protein_2": "SSPN", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1571667], "include_positive": false}}
+{"question_id": "PPIL2-0446", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- LGALS7 and RUVBL2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "LGALS7", "protein_2": "RUVBL2", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [221901], "include_positive": false}}
+{"question_id": "PPIL2-0447", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- SMARCD2 and TGFBR1: no interaction detected\n- TOMM20 and GFRA1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SMARCD2", "protein_2": "TGFBR1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TOMM20", "protein_2": "GFRA1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [837319, 1999255], "include_positive": false}}
+{"question_id": "PPIL2-0448", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- P2RY14 and NT5DC1: no interaction detected\n- BLZF1 and TCF21: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "P2RY14", "protein_2": "NT5DC1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "BLZF1", "protein_2": "TCF21", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2059804, 65299], "include_positive": false}}
+{"question_id": "PPIL2-0449", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- KRT79 and NOX5: no interaction detected\n- PPP4R1 and QRSL1: no interaction detected\n- BCL2 and ATP5F1A: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KRT79", "protein_2": "NOX5", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PPP4R1", "protein_2": "QRSL1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "BCL2", "protein_2": "ATP5F1A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2103789, 1168879, 875738], "include_positive": true}}
+{"question_id": "PPIL2-0450", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CD69 and ALKBH4: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CD69", "protein_2": "ALKBH4", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [282327], "include_positive": true}}
+{"question_id": "PPIL2-0451", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TIMM10 and CFH: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TIMM10", "protein_2": "CFH", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1559493], "include_positive": true}}
+{"question_id": "PPIL2-0452", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BORCS8 and CCNL1: no interaction detected\n- SHISAL2A and C15orf62: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BORCS8", "protein_2": "CCNL1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SHISAL2A", "protein_2": "C15orf62", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1308457, 1758133], "include_positive": true}}
+{"question_id": "PPIL2-0453", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- EIF2S3 and SDC1: no interaction detected\n- ZKSCAN4 and RAB2A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EIF2S3", "protein_2": "SDC1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ZKSCAN4", "protein_2": "RAB2A", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [682686, 254888], "include_positive": false}}
+{"question_id": "PPIL2-0454", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- AIMP2 and COG4: no interaction detected\n- RBM15 and STIMATE-MUSTN1: no interaction detected\n- RAD21 and KCNIP2: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AIMP2", "protein_2": "COG4", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RBM15", "protein_2": "STIMATE-MUSTN1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RAD21", "protein_2": "KCNIP2", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1213307, 1774600, 597045], "include_positive": false}}
+{"question_id": "PPIL2-0455", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- STPG3 and TSHR: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STPG3", "protein_2": "TSHR", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1914138], "include_positive": false}}
+{"question_id": "PPIL2-0456", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- KCNIP1 and ARID4A: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "KCNIP1", "protein_2": "ARID4A", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [698419], "include_positive": false}}
+{"question_id": "PPIL2-0457", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BIN1 and SPTSSB: no interaction detected\n- CNOT3 and MRPS14: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BIN1", "protein_2": "SPTSSB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CNOT3", "protein_2": "MRPS14", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1241962, 1537795], "include_positive": false}}
+{"question_id": "PPIL2-0458", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP1A1 and A0A024RAD5: no interaction detected\n- RNF128 and ERBB3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP1A1", "protein_2": "A0A024RAD5", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RNF128", "protein_2": "ERBB3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [1310115, 1926300], "include_positive": false}}
+{"question_id": "PPIL2-0459", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- STARD13 and UQCC1: no interaction detected\n- KAT2A and CD8B: no interaction detected\n- ISCA2 and BICRA: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "STARD13", "protein_2": "UQCC1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "KAT2A", "protein_2": "CD8B", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "ISCA2", "protein_2": "BICRA", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2234141, 1368050, 1569538], "include_positive": false}}
+{"question_id": "PPIL2-0460", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PIGS and C4B: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PIGS", "protein_2": "C4B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1487163], "include_positive": true}}
+{"question_id": "PPIL2-0461", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- POLR2E and GPAA1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "POLR2E", "protein_2": "GPAA1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1430877], "include_positive": true}}
+{"question_id": "PPIL2-0462", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MAFG and PIDD1: no interaction detected\n- PRIM2 and ITGAX: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MAFG", "protein_2": "PIDD1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "PRIM2", "protein_2": "ITGAX", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [808058, 1677366], "include_positive": false}}
+{"question_id": "PPIL2-0463", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ETV6 and PLD3: no interaction detected\n- KAT2A and MBTD1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ETV6", "protein_2": "PLD3", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "KAT2A", "protein_2": "MBTD1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [213727, 619414], "include_positive": false}}
+{"question_id": "PPIL2-0464", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ACTR5 and AP3B2: no interaction detected\n- RANBP9 and TMEM74: no interaction detected\n- EIF2AK2 and AP1AR: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ACTR5", "protein_2": "AP3B2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RANBP9", "protein_2": "TMEM74", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "EIF2AK2", "protein_2": "AP1AR", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [796188, 467218, 175977], "include_positive": true}}
+{"question_id": "PPIL2-0465", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- RNASEH1 and DYNLT5: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "RNASEH1", "protein_2": "DYNLT5", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [81081], "include_positive": true}}
+{"question_id": "PPIL2-0466", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- SGK1 and RAP2C: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SGK1", "protein_2": "RAP2C", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [25672], "include_positive": false}}
+{"question_id": "PPIL2-0467", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- DELE1 and RNF38: no interaction detected\n- ZNF581 and NAGA: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "DELE1", "protein_2": "RNF38", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "ZNF581", "protein_2": "NAGA", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [304463, 1915738], "include_positive": true}}
+{"question_id": "PPIL2-0468", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- IFNL4 and ETFB: no interaction detected\n- RRM1 and EXOC4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IFNL4", "protein_2": "ETFB", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RRM1", "protein_2": "EXOC4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [977182, 658099], "include_positive": false}}
+{"question_id": "PPIL2-0469", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- ITM2C and PCDHGB6: no interaction detected\n- SLC25A35 and SNX5: no interaction detected\n- KMT2D and ACTR6: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ITM2C", "protein_2": "PCDHGB6", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "SLC25A35", "protein_2": "SNX5", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "KMT2D", "protein_2": "ACTR6", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2232482, 332662, 1216049], "include_positive": false}}
+{"question_id": "PPIL2-0470", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TOP3B and CHMP1B: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TOP3B", "protein_2": "CHMP1B", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [594913], "include_positive": false}}
+{"question_id": "PPIL2-0471", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- MAFG and CRBN: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MAFG", "protein_2": "CRBN", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [810278], "include_positive": false}}
+{"question_id": "PPIL2-0472", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- IGFN1 and RAB7B: no interaction detected\n- BRCA1 and AP3D1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "IGFN1", "protein_2": "RAB7B", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "BRCA1", "protein_2": "AP3D1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2145008, 1374245], "include_positive": false}}
+{"question_id": "PPIL2-0473", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- MTCL2 and BLMH: no interaction detected\n- CCNY and TRAPPC11: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "MTCL2", "protein_2": "BLMH", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CCNY", "protein_2": "TRAPPC11", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [101122, 1482354], "include_positive": false}}
+{"question_id": "PPIL2-0474", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- PIK3R3 and MTA3: no interaction detected\n- SNRPA1 and CEBPG: no interaction detected\n- CENPK and BATF3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PIK3R3", "protein_2": "MTA3", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SNRPA1", "protein_2": "CEBPG", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "CENPK", "protein_2": "BATF3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [777063, 516829, 1293018], "include_positive": false}}
+{"question_id": "PPIL2-0475", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP6AP2 and FSHB: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP6AP2", "protein_2": "FSHB", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [766585], "include_positive": false}}
+{"question_id": "PPIL2-0476", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ACTMAP and AKAP14: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ACTMAP", "protein_2": "AKAP14", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [342388], "include_positive": true}}
+{"question_id": "PPIL2-0477", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- CLEC18A and CD151: no interaction detected\n- EFCAB12 and G3V4G9: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "CLEC18A", "protein_2": "CD151", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "EFCAB12", "protein_2": "G3V4G9", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [10940, 1774097], "include_positive": false}}
+{"question_id": "PPIL2-0478", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- POLD1 and HBG2: no interaction detected\n- SCNN1A and CSNK1A1: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "POLD1", "protein_2": "HBG2", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "SCNN1A", "protein_2": "CSNK1A1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [815225, 791919], "include_positive": false}}
+{"question_id": "PPIL2-0479", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- AKR1C1 and RABEP1: no interaction detected\n- MED11 and FYTTD1: no interaction detected\n- RRP8 and INTS1: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AKR1C1", "protein_2": "RABEP1", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MED11", "protein_2": "FYTTD1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "RRP8", "protein_2": "INTS1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [2026673, 974857, 926130], "include_positive": false}}
+{"question_id": "PPIL2-0480", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GCSH and SLC26A6: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GCSH", "protein_2": "SLC26A6", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1930181], "include_positive": false}}
+{"question_id": "PPIL2-0481", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- GSDME and SMC3: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GSDME", "protein_2": "SMC3", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1823692], "include_positive": false}}
+{"question_id": "PPIL2-0482", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SAMD9 and FGFR2: no interaction detected\n- MEN1 and IGLC1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SAMD9", "protein_2": "FGFR2", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MEN1", "protein_2": "IGLC1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [1926117, 646292], "include_positive": true}}
+{"question_id": "PPIL2-0483", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- L3MBTL4 and FAM200A: no interaction detected\n- HPS6 and MBOAT2: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "L3MBTL4", "protein_2": "FAM200A", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "HPS6", "protein_2": "MBOAT2", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [423962, 2130764], "include_positive": false}}
+{"question_id": "PPIL2-0484", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TRA2A and SEC16B: no interaction detected\n- HSBP1L1 and RAP2C: no interaction detected\n- FNTA and ATP6V0D1: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRA2A", "protein_2": "SEC16B", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "HSBP1L1", "protein_2": "RAP2C", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "FNTA", "protein_2": "ATP6V0D1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "huri", "result_ids": [299787, 21733, 919912], "include_positive": false}}
+{"question_id": "PPIL2-0485", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TSPAN7 and NRK: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TSPAN7", "protein_2": "NRK", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1969656], "include_positive": false}}
+{"question_id": "PPIL2-0486", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ATP10D and ITGB3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ATP10D", "protein_2": "ITGB3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1070851], "include_positive": false}}
+{"question_id": "PPIL2-0487", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- AP1G1 and SLC6A15: no interaction detected\n- DPY30 and FCN1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "AP1G1", "protein_2": "SLC6A15", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "DPY30", "protein_2": "FCN1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [67443, 1509564], "include_positive": true}}
+{"question_id": "PPIL2-0488", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- THAP3 and MUC13: no interaction detected\n- RPL36AL and CTRC: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "THAP3", "protein_2": "MUC13", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "RPL36AL", "protein_2": "CTRC", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2187950, 449920], "include_positive": false}}
+{"question_id": "PPIL2-0489", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- TRAPPC2L and MTOR: no interaction detected\n- TRAF3IP1 and MRPL40: no interaction detected\n- CFAP157 and CPN1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRAPPC2L", "protein_2": "MTOR", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRAF3IP1", "protein_2": "MRPL40", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "CFAP157", "protein_2": "CPN1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [1123027, 436454, 1910768], "include_positive": true}}
+{"question_id": "PPIL2-0490", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- TRA2A and TMEM212: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TRA2A", "protein_2": "TMEM212", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "string", "result_ids": [1755402], "include_positive": false}}
+{"question_id": "PPIL2-0491", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- GUCY1A1 and MSL3: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "GUCY1A1", "protein_2": "MSL3", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1551004], "include_positive": false}}
+{"question_id": "PPIL2-0492", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ZBTB4 and NKX1-2: no interaction detected\n- LSM6 and SPC25: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZBTB4", "protein_2": "NKX1-2", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "LSM6", "protein_2": "SPC25", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [497079, 1655209], "include_positive": true}}
+{"question_id": "PPIL2-0493", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- EPC1 and ICE1: no interaction detected\n- TRIM14 and SERPINB7: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "EPC1", "protein_2": "ICE1", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "TRIM14", "protein_2": "SERPINB7", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "humap", "result_ids": [737200, 1840347], "include_positive": false}}
+{"question_id": "PPIL2-0494", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- PPP1CC and VCPKMT: no interaction detected\n- MAX and BAZ2A: no interaction detected\n- H2AB2 and SP1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "PPP1CC", "protein_2": "VCPKMT", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "MAX", "protein_2": "BAZ2A", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "H2AB2", "protein_2": "SP1", "method": "binding assay", "evidence_strength": "weak"}], "total_negative_count": 3, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 3, "source_db": "string", "result_ids": [1964354, 1658267, 1884652], "include_positive": true}}
+{"question_id": "PPIL2-0495", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- ZZZ3 and ATP6V1C1: no interaction detected\n- Several other tested pairs showed positive interactions", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZZZ3", "protein_2": "ATP6V1C1", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 1, "positive_interactions_mentioned": true}, "metadata": {"n_pairs": 1, "source_db": "humap", "result_ids": [1013798], "include_positive": true}}
+{"question_id": "PPIL2-0496", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- TCTA and BTBD3: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "TCTA", "protein_2": "BTBD3", "method": "binding assay", "evidence_strength": "strong"}], "total_negative_count": 1, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 1, "source_db": "huri", "result_ids": [250131], "include_positive": false}}
+{"question_id": "PPIL2-0497", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "An integrated analysis across multiple evidence channels evaluated potential interactions between several protein pairs.\n\n- SLC16A9 and HRH4: no interaction detected\n- PLRG1 and PIGG: no interaction detected", "gold_answer": "binding assay", "gold_category": "string", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "SLC16A9", "protein_2": "HRH4", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "PLRG1", "protein_2": "PIGG", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "string", "result_ids": [2135350, 1089893], "include_positive": false}}
+{"question_id": "PPIL2-0498", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "A systematic yeast two-hybrid screen tested a panel of human protein pairs for binary interactions.\n\n- ZDHHC23 and CALCOCO1: no interaction detected\n- UBE2V2 and TAF8: no interaction detected", "gold_answer": "binding assay", "gold_category": "huri", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "ZDHHC23", "protein_2": "CALCOCO1", "method": "binding assay", "evidence_strength": "strong"}, {"protein_1": "UBE2V2", "protein_2": "TAF8", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 2, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 2, "source_db": "huri", "result_ids": [409632, 1490604], "include_positive": false}}
+{"question_id": "PPIL2-0499", "task": "ppi-l2", "split": "test", "difficulty": "medium", "context_text": "Computational analysis of co-fractionation proteomics data was used to predict protein complex membership for multiple protein pairs.\n\n- BLOC1S2 and PSMC3IP: no interaction detected\n- KCNE4 and SLC26A10P: no interaction detected\n- BLZF1 and LAMTOR4: no interaction detected", "gold_answer": "binding assay", "gold_category": "humap", "gold_extraction": {"non_interacting_pairs": [{"protein_1": "BLOC1S2", "protein_2": "PSMC3IP", "method": "binding assay", "evidence_strength": "moderate"}, {"protein_1": "KCNE4", "protein_2": "SLC26A10P", "method": "binding assay", "evidence_strength": "weak"}, {"protein_1": "BLZF1", "protein_2": "LAMTOR4", "method": "binding assay", "evidence_strength": "moderate"}], "total_negative_count": 3, "positive_interactions_mentioned": false}, "metadata": {"n_pairs": 3, "source_db": "humap", "result_ids": [960891, 2177630, 777023], "include_positive": false}}