Datasets:
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<p align="center">
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<img src="figures/data_overview.png" alt="Dataset overview" width="750"/>
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<em>Overview of the benchmark setting: experimental batches contain perturbed samples and negative controls, enabling control-stabilized adaptation under batch effects and label shift.</em>
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[](https://arxiv.org/abs/2604.20824)
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[](https://github.com/ml-jku/cs-arm-bn)
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# Multi-Source Domain Adaptation for Bioimaging Data (MSCDA-BioIm)
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**MSCDA-BioIm** is a biomedical microscopy benchmark for evaluating test-time and in-context domain adaptation under realistic batch effects. Built from the large-scale JUMP-CP dataset, it targets mechanism-of-action (MoA) classification using five-channel images of compounds associated with eight well-defined MoA classes. The dataset is organized by experimental batches and imaging sources, enabling controlled evaluation of generalization to unseen batches, cross-source transfer, small target context sizes, and label-shifted target batches.
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[](https://arxiv.org/abs/2604.20824)
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[](https://github.com/ml-jku/cs-arm-bn)
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<p align="center">
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<img src="figures/data_overview.png" alt="Dataset overview" width="750"/>
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</p>
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<p align="center">
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</p>
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# Multi-Source Domain Adaptation for Bioimaging Data (MSCDA-BioIm)
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**MSCDA-BioIm** is a biomedical microscopy benchmark for evaluating test-time and in-context domain adaptation under realistic batch effects. Built from the large-scale JUMP-CP dataset, it targets mechanism-of-action (MoA) classification using five-channel images of compounds associated with eight well-defined MoA classes. The dataset is organized by experimental batches and imaging sources, enabling controlled evaluation of generalization to unseen batches, cross-source transfer, small target context sizes, and label-shifted target batches.
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