| Year Title Role Notes |
| 1978 The Big Fix Pool Man |
| 1979 French Postcards Sayyid |
| 1979 Last Embrace First Commuter |
| 1980 Night of the Juggler Allesandro the Cabbie |
| 1981 Ragtime Tateh |
| 1983 Yentl Avigdor Nominated—Golden Globe Award for Best Actor – Motion Picture Musical or Comedy |
| 1983 Daniel Paul Isaacson |
| 1985 Maxie Nick |
| 1986 Tenkû no shiro Rapyuta Louis |
| 1987 The Princess Bride Inigo Montoya |
| 1988 Alien Nation Detective Samuel 'George' Francisco Nominated—Saturn Award for Best Supporting Actor |
| 1988 The House on Carroll Street Ray Salwen |
| 1990 Dick Tracy 88 Keys |
| 1991 True Colors John Palmeri |
| 1991 Impromptu Alfred de Musset |
| 1991 The Doctor Dr. Murray Kaplan |
| 1993 The Music of Chance Jim Nashe |
| 1993 Life with Mikey Irate Man |
| 1994 Squanto: A Warrior's Tale Brother Daniel |
| 1998 Lulu On The Bridge Philip Kleinman |
| 1998 Men with Guns Andrew |
| 1999 The Adventures of Elmo in Grouchland Huxley |
| 2001 Piñero Joseph Papp |
| 2002 Run Ronnie Run Himself |
| 2003 Celebrity Train Layouts: Mandy Patinkin Himself |
| 2005 The Choking Man Rick |
| 2006 Everyone's Hero Stanley Irving |
| 2010 4.3.2.1 ... The Countdown Begins Jago L |
| 2014 Wish I Was Here Saul Bloom |
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