Year	Title	Role	Notes
1993	Class of '61	Lily Magraw	TV movie
1993	Blind Spot	Phoebe	TV movie
1993	Tales of the City	Mary Ann Singleton	Miniseries; 7 episodes
1994	Law & Order	Martha Bowen	Episode: "Blue Bamboo"
1998	More Tales of the City	Mary Ann Singleton	Miniseries; 6 episodes
1999	Love Letters	Melisa Gardner Cobb	TV movie
2000	Running Mates	Lauren Hartman	TV movie
2001	Further Tales of the City	Mary Ann Singleton	Miniseries; 3 episodes
2001	Wild Iris	Iris Bravard	TV movie
2002	King of the Hill	Marlene	Voice; Episode: "Dang Ol' Love"
2003–2004	Frasier	Mindy / Charlotte	6 episodes
2006	American Dad!	Doctor Gupta	Voice; Episode: "Roger 'n' Me"
2008	John Adams	Abigail Adams	Miniseries; 7 episodes
2010–2013	The Big C	Cathy Jamison	40 episodes, also executive producer
2016	Inside Amy Schumer	Herself	Episode: "Brave"
2017	Red Nose Day Actually	Sarah	Television short film
2017	Last Week Tonight with John Oliver	Florence Harding	Segment: "Harding"
2017–present	Ozark	Wendy Byrde	20 episodes
2017	Sink Sank Sunk	Mitzi Mills	TV movie
2018	BoJack Horseman	Herself	Voice; Episode: "The Dog Days Are Over"
2019	Tales of the City	Mary Ann Singleton	Main cast
2019	Portrait Artist of the Year	Herself	Sitter for the finale