| Year,Title,Role,Notes | |
| 2001,Crust,Receptionist,- | |
| 2002,Living In Hope,Ginny,- | |
| 2002,Anansi,Carla,- | |
| 2002,28 Days Later,Selena,- | |
| 2004,Trauma,Elisa,- | |
| 2004,After the Sunset,Sophie,- | |
| 2006,Pirates of the Caribbean: Dead Man's Chest,Tia Dalma,- | |
| 2006,Miami Vice,Trudy Joplin,- | |
| 2006,A Cock and Bull Story,Jennie,- | |
| 2007,Pirates of the Caribbean: At World's End,Tia Dalma / Calypso,- | |
| 2008,Street Kings,Linda Washington,- | |
| 2008,Explicit Ills,Jill,- | |
| 2008,August,Sarah,- | |
| 2009,Morris: A Life with Bells On,Sonja,- | |
| 2009,Ninja Assassin,Mika Coretti,- | |
| 2009,Sex & Drugs & Rock & Roll,Denise,- | |
| 2009,My Last Five Girlfriends,Gemma,- | |
| 2010,The First Grader,Jane Obinchu,- | |
| 2012,Skyfall,Eve Moneypenny,- | |
| 2013,Mandela: Long Walk to Freedom,Winnie Mandela,- | |
| 2015,Southpaw,Angela Rivera,- | |
| 2015,Spectre,Eve Moneypenny,- | |
| 2016,Our Kind of Traitor,Gail Perkins,- | |
| 2016,Moonlight,Paula,- | |
| 2016,Collateral Beauty,Madeleine,- | |
| 2018,Rampage,Dr. Kate Caldwell,- | |
| 2018,Mowgli: Legend of the Jungle,Nisha,Motion-capture and voice | |
| 2019,Black and Blue,-,Post-production | |
| 2020,Bond 25,Eve Moneypenny,Filming | |