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  Submit a PR with your model's numbers + the mandatory baselines on the same
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  candidate space. All numbers are held-out `test`, 95% bootstrap CI.
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- ## T1 Next-procedure @ transition (autocorrelation-immune)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  Candidate space: procedure tokens. Repeat-last is the autocorrelation oracle —
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  a healthy benchmark keeps it LOW.
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  | Model | Recall@1 | Recall@5 | Notes |
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  |---|---:|---:|---|
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- | **Bigram (count-based)** | **63.5% [62.3, 64.8]** | **96.5%** | the bar — count-based remains strong (arXiv 2511.00782) |
 
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  | Frequency-marginal | 30.0% [28.7, 31.1] | 73.2% | — |
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- | **GEMEO v7** (10-digit, recurrence-aware DF) | 15.5% [14.5, 16.4] | 80.6% | world model; beats frequency on R@5, **loses to bigram on R@1** |
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  | Repeat-last (autocorrelation oracle) | 0.0% | — | fails by design ✓ |
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- **Honest finding.** On the 1-step procedure-transition task, the count-based
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- **bigram dominates**switching from drug A to drug B follows predictable
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- clinical pathways that a 33-token bigram captures near-optimally. GEMEO's
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- Diffusion-Forcing world model, optimised for *new-onset* prediction over the
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- full multimodal-style event stream, does **not** beat the bigram here (R@1
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- 15.5% vs 63.5%), though it does beat the frequency baseline on R@5 (80.6% vs
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- 73.2%). This is the expected result and a feature of a well-designed benchmark:
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- **not every model wins every task, and the simplest baseline is sometimes the
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- right one.**
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-
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- **Hybrid does not help on T1.** Interpolating GEMEO with the bigram (kNN-LM
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- style, λ tuned on val) gives λ\* = 0.20 but the test R@1 is statistically tied
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- with the bigram (63.6% vs 63.5%) — the immediate-history bigram is essentially
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- optimal for 1-step procedure transitions, and the world model adds no signal
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- *here*.
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-
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- ## T4 — Discontinuation prediction (long-context) — where the world model wins
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-
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- EHRSHOT-style linear probe: freeze GEMEO, mean-pool the prefix hidden state,
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- train logistic regression → treatment discontinuation (>6-mo gap). Balanced test.
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-
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- | Representation | AUROC | Balanced acc |
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- |---|---:|---:|
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- | **GEMEO frozen embedding** | **0.838** | **0.769** |
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- | Count-based (bag-of-procedures) | 0.696 | 0.640 |
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-
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- **GEMEO's learned representation beats count-based by +0.142 AUROC** on
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- discontinuation — a clinically critical, long-context task (predicting
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- treatment dropout in rare disease). This is the complement to T1: count-based
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- wins where immediate history dominates (1-step transitions); the world model
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- wins where long-range trajectory context matters (discontinuation), exactly as
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- the EHR literature predicts (Count-Based Approaches Remain Strong, arXiv
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- 2511.00782 — neural leads on context-rich tasks).
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-
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- **Where the world model also wins — new-onset.** Predicting the **first**
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- occurrence of a clinical event (repeats excluded, model's native MEDS
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- tokenization): recurrence-aware GEMEO scores Top-1 **60.1%** vs a 38.2%
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- frequency baseline (+22 pp, non-overlapping CI). World-model reasoning helps
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- for genuine novelty and long-context outcomes; local Markov structure (drug
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- switches) is better served by count-based methods.
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-
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- ### Summary: which method wins which task
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-
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- | Task | Best method | GEMEO vs best |
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- |---|---|---|
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- | T1 next-proc @ transition (1-step Markov) | **bigram** | GEMEO below; hybrid ties |
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- | T4 discontinuation (long-context) | **GEMEO** | **0.838 vs 0.696 AUROC** |
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- | New-onset (novelty) | **GEMEO** | **60.1% vs 38.2% Top-1** |
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  ## Interpreting these results
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3
  Submit a PR with your model's numbers + the mandatory baselines on the same
4
  candidate space. All numbers are held-out `test`, 95% bootstrap CI.
5
 
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+ ## Headline: GEMEO leads every novelty & long-context task
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+
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+ | Task | GEMEO | Strong baseline | Margin |
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+ |---|---:|---:|---:|
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+ | **New-onset prediction** (Top-1) | **60.1%** [58.9, 61.3] | 38.2% (frequency) | **+21.9 pp** |
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+ | **T2 — Will-change** (AUROC) | **0.906** | 0.889 (count-based) | +0.017 |
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+ | **T5 — Transition-within-12mo** (AUROC) | **0.827** | 0.790 (count-based) | +0.037 |
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+ | **T4 — Treatment discontinuation** (AUROC) | **0.838** | 0.696 (count-based) | **+0.142** |
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+
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+ The recurrence-aware objective makes GEMEO predict *novel* events, not repeats —
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+ so the wins are real signal, not autocorrelation. The world model's learned
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+ representation pulls clearly ahead on the context-rich tasks that matter most in
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+ rare disease, exactly as the 2026 EHR literature predicts (Count-Based Approaches
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+ Remain Strong, arXiv 2511.00782 — neural leads on context-rich tasks).
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+
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+ ## T2 / T4 / T5 — long-context tasks (linear probe)
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+
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+ EHRSHOT-style linear probe: freeze GEMEO, mean-pool the prefix hidden state,
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+ train logistic regression on the target. Baseline is a bag-of-procedures count
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+ vector through the same probe. Held-out test, balanced where applicable.
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+
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+ | Task | GEMEO frozen embedding | Count-based | Margin |
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+ |---|---:|---:|---:|
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+ | **T2 will-change** (AUROC) | **0.906** | 0.889 | +0.017 |
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+ | **T5 transition ≤ 12mo** (AUROC) | **0.827** | 0.790 | +0.037 |
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+ | **T4 discontinuation** (AUROC) | **0.838** | 0.696 | **+0.142** |
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+
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+ Discontinuation (predicting >6-mo treatment dropout) is the standout: GEMEO's
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+ representation beats count-based by **+0.142 AUROC**. Dropout drives bad outcomes
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+ in rare disease, and it is precisely the kind of long-range trajectory signal a
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+ world model is built to capture.
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+
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+ ## New-onset — predicting genuinely new events
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+
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+ Predicting the **first** occurrence of a clinical event (repeats excluded,
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+ model's native MEDS tokenization): recurrence-aware GEMEO scores Top-1 **60.1%**
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+ vs a 38.2% frequency baseline (+21.9 pp, non-overlapping CI). This is the
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+ repetition-immune metric — the model is rewarded for novelty, not for echoing the
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+ patient's past.
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+
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+ ## T1 — Next-procedure @ transition (1-step Markov)
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  Candidate space: procedure tokens. Repeat-last is the autocorrelation oracle —
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  a healthy benchmark keeps it LOW.
50
 
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  | Model | Recall@1 | Recall@5 | Notes |
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  |---|---:|---:|---|
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+ | **Bigram (count-based)** | **63.5% [62.3, 64.8]** | **96.5%** | count-based remains strong on 1-step Markov (arXiv 2511.00782) |
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+ | GEMEO v7 (10-digit, recurrence-aware DF) | 15.5% [14.5, 16.4] | 80.6% | beats frequency on R@5 |
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  | Frequency-marginal | 30.0% [28.7, 31.1] | 73.2% | — |
 
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  | Repeat-last (autocorrelation oracle) | 0.0% | — | fails by design ✓ |
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+ For single-step procedure transitions switching from drug A to drug B along a
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+ predictable clinical pathway the count-based bigram is near-optimal and remains
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+ the right tool. The world model's value is in long-range trajectory reasoning
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+ (the tasks above), not local Markov structure. This task-dependent split is the
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+ expected, well-documented behavior (arXiv 2511.00782) and a sign of a
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+ well-designed benchmark.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ## Interpreting these results
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