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---
license: cc-by-4.0
task_categories:
- feature-extraction
language:
- en
tags:
- biology
- siRNA
- oligonucleotide-therapeutics
- chemical-modification
- sequence-modeling
- patent
pretty_name: Patent-linked modified siRNA sequences
size_categories:
- 1M<n<10M
---
🧬 **Dataset Summary**

Patent-linked nucleotide sequence records focused RNAi therapeutics patent portfolio. Each record pairs a raw nucleotide sequence with its source patent number, publication date, and global patent family coverage.

**🚀 Key Features**

- **Patent Linkage:** Each sequence is tied to a patent number (`pn`) and publication date (`pbdt`), enabling sequence-to-IP traceability.
- **Global Family Coverage:** `family_country` lists all jurisdictions in the patent family (e.g., US, EP, CN, JP, WO).
- **Patent Status:** `status` field tracks the current patent lifecycle state.
- **Modification Tracking:** `modified_info` captures amendment history where available (~8.6% of records).

**💻 Quick Start & MCP Integration**

```python
from datasets import load_dataset

dataset = load_dataset("your-org/alnylam-sequences", split="train")
print(dataset[0]["sequence"])
# Output: 'atcacacgcacacacaaaagaag'
print(dataset[0]["pn"])
# Output: 'EP4416284A1'
print(dataset[0]["family_country"])
# Output: ['JP', 'NZ', 'EA', 'SG', 'CN', 'MX', 'AU', 'IN', 'US', 'EP', 'WO', 'HK', 'IL', 'ZA', 'CA', 'KR']
```

---

## 🔗 Resources
- **Developer Portal**: [open.patsnap.com](https://open.patsnap.com)
- **PatSnap Life Sciences**: [patsnap.com/solutions/life-sciences](https://www.patsnap.com/solutions/life-sciences/)
- **GitHub**: [github.com/patsnap](https://github.com/patsnap)