---
license: other
license_name: penn-license
license_link: LICENSE
viewer: false
tags:
- SpatialTranscriptomics
- VirtualPrediction
---
**AURORA (Architecture Unveiling through RNA Omics and Routine Histology Analysis)**

- `trained_models`: Pretrained AURORA models for LUAD, KIRC and BRCA.
  - `*.pth`: model weight;
  - `*.json`: parameters for the AURORA model;
  - `*.csv`: supporting information (cell types, gene names and normalizing factors) used by `*.json`.

- `predictions_112um`: Virtual spatial transcriptomics at 112 μm * 112 μm by AURORA of TCGA-LUAD, TCGA-KIRC, TCGA-BRCA and BRCA pre-chemotherapy (https://doi.org/10.1038/s41586-021-04278-5) samples. 
  - `*.h5` file: virtual spatial transcriptomics
    - `pos`: spatial coordinates of patches (224 pixels * 224 pixels). This is the coordinates of the upper left corner of each patch.
    - `gene_exp`: gene expressions. The names of the genes are stored in `genes.csv`.
    - `celltype_prop`: cell type proportions in **log** scales. The name of the cell types are stored in `celltypes.csv`.
  - `genes.csv`: names of predicted genes.
  - `celltypes.csv`: names of predicted cell types.